#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P22891	uniprotkb:Q9UK55	intact:EBI-22220337|uniprotkb:A6NMB4|uniprotkb:Q15213|uniprotkb:Q5JVF5|uniprotkb:Q5JVF6|ensembl:ENSP00000364697	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:proz_human(display_long)|uniprotkb:PROZ(gene name)|psi-mi:PROZ(display_short)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22224199|wwpdb:3h5c|imex:IM-27863-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243063.1|refseq:NP_003882.1|ensembl:ENSG00000126231(gene)|ensembl:ENST00000375547(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR035972|interpro:IPR043504|rcsb pdb:3F1S|rcsb pdb:3H5C|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	-	-	figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/18	2020/04/09	rogid:a3TU2GY7jzWdoqC2rQow8qraOaA9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:1j0+q7IHp0Bx22yajBp/S4aQZRY	false	sufficient binding region:84-400	sufficient binding region:22-444	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22891	uniprotkb:Q9UK55	intact:EBI-22220337|uniprotkb:A6NMB4|uniprotkb:Q15213|uniprotkb:Q5JVF5|uniprotkb:Q5JVF6|ensembl:ENSP00000364697	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:proz_human(display_long)|uniprotkb:PROZ(gene name)|psi-mi:PROZ(display_short)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22224218|imex:IM-27863-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243063.1|refseq:NP_003882.1|ensembl:ENSG00000126231(gene)|ensembl:ENST00000375547(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR035972|interpro:IPR043504|rcsb pdb:3F1S|rcsb pdb:3H5C|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	-	-	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/18	2019/12/12	rogid:a3TU2GY7jzWdoqC2rQow8qraOaA9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:1j0+q7IHp0Bx22yajBp/S4aQZRY	false	sufficient binding region:84-400	mutation disrupting interaction strength:95-95,259-260,404-404|sufficient binding region:22-444|mutation with no effect:334-334,404-404|mutation with no effect:334-334|mutation with no effect:404-404	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P00742	uniprotkb:Q9UK55	intact:EBI-719750|uniprotkb:Q14340|ensembl:ENSP00000364709	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:fa10_human(display_long)|uniprotkb:Stuart factor(gene name synonym)|uniprotkb:Stuart-Prower factor(gene name synonym)|uniprotkb:F10(gene name)|psi-mi:F10(display_short)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22304181|imex:IM-27863-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000495.1|ensembl:ENSG00000126218(gene)|ensembl:ENST00000375559(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035972|interpro:IPR043504|mint:P00742|rcsb pdb:1C5M|rcsb pdb:1EZQ|rcsb pdb:1F0R|rcsb pdb:1F0S|rcsb pdb:1FAX|rcsb pdb:1FJS|rcsb pdb:1FXY|rcsb pdb:1G2L|rcsb pdb:1G2M|rcsb pdb:1HCG|rcsb pdb:1IOE|rcsb pdb:1IQE|rcsb pdb:1IQF|rcsb pdb:1IQG|rcsb pdb:1IQH|rcsb pdb:1IQI|rcsb pdb:1IQJ|rcsb pdb:1IQK|rcsb pdb:1IQL|rcsb pdb:1IQM|rcsb pdb:1IQN|rcsb pdb:1KSN|rcsb pdb:1LPG|rcsb pdb:1LPK|rcsb pdb:1LPZ|rcsb pdb:1LQD|rcsb pdb:1MQ5|rcsb pdb:1MQ6|rcsb pdb:1MSX|rcsb pdb:1NFU|rcsb pdb:1NFW|rcsb pdb:1NFX|rcsb pdb:1NFY|rcsb pdb:1NL8|rcsb pdb:1P0S|rcsb pdb:1V3X|rcsb pdb:1WU1|rcsb pdb:1XKA|rcsb pdb:1XKB|rcsb pdb:1Z6E|rcsb pdb:2BMG|rcsb pdb:2BOH|rcsb pdb:2BOK|rcsb pdb:2BQ6|rcsb pdb:2BQ7|rcsb pdb:2BQW|rcsb pdb:2CJI|rcsb pdb:2D1J|rcsb pdb:2EI6|rcsb pdb:2EI7|rcsb pdb:2EI8|rcsb pdb:2FZZ|rcsb pdb:2G00|rcsb pdb:2GD4|rcsb pdb:2H9E|rcsb pdb:2J2U|rcsb pdb:2J34|rcsb pdb:2J38|rcsb pdb:2J4I|rcsb pdb:2J94|rcsb pdb:2J95|rcsb pdb:2P16|rcsb pdb:2P3F|rcsb pdb:2P3T|rcsb pdb:2P3U|rcsb pdb:2P93|rcsb pdb:2P94|rcsb pdb:2P95|rcsb pdb:2PHB|rcsb pdb:2PR3|rcsb pdb:2Q1J|rcsb pdb:2RA0|rcsb pdb:2UWL|rcsb pdb:2UWO|rcsb pdb:2UWP|rcsb pdb:2VH0|rcsb pdb:2VH6|rcsb pdb:2VVC|rcsb pdb:2VVU|rcsb pdb:2VVV|rcsb pdb:2VWL|rcsb pdb:2VWM|rcsb pdb:2VWN|rcsb pdb:2VWO|rcsb pdb:2W26|rcsb pdb:2W3I|rcsb pdb:2W3K|rcsb pdb:2WYG|rcsb pdb:2WYJ|rcsb pdb:2XBV|rcsb pdb:2XBW|rcsb pdb:2XBX|rcsb pdb:2XBY|rcsb pdb:2XC0|rcsb pdb:2JKH|rcsb pdb:2XC4|rcsb pdb:2XC5|rcsb pdb:2Y5F|rcsb pdb:2Y5G|rcsb pdb:2Y5H|rcsb pdb:2Y7X|rcsb pdb:2Y7Z|rcsb pdb:2Y80|rcsb pdb:2Y81|rcsb pdb:2Y82|rcsb pdb:3CEN|rcsb pdb:3CS7|rcsb pdb:3ENS|rcsb pdb:3FFG|rcsb pdb:3HPT|rcsb pdb:3IIT|rcsb pdb:3K9X|rcsb pdb:3KL6|rcsb pdb:3KQB|rcsb pdb:3KQC|rcsb pdb:3KQD|rcsb pdb:3KQE|rcsb pdb:3LIW|rcsb pdb:3M36|rcsb pdb:3M37|rcsb pdb:3Q3K|rcsb pdb:3SW2|rcsb pdb:3TK6|rcsb pdb:4A7I|rcsb pdb:4BTI|rcsb pdb:4BTT|rcsb pdb:4BTU|rcsb pdb:4Y6D|rcsb pdb:4Y71|rcsb pdb:4Y76|rcsb pdb:4Y79|rcsb pdb:4Y7A|rcsb pdb:4Y7B|rcsb pdb:4ZH8|rcsb pdb:4ZHA|rcsb pdb:5JQY|rcsb pdb:5JTC|rcsb pdb:5JZ8|rcsb pdb:5JZU|rcsb pdb:5K0H|rcsb pdb:5VOE|rcsb pdb:5VOF|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6RK9|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|rcsb pdb:3TK5|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|refseq:NP_001299603.1|refseq:NP_001299604.1|dip:DIP-29896N	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	-	-	figure legend:Fig. 8|comment:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/18	2019/12/12	rogid:EiG38fLKwrbGJftF5k4xjLvlYhA9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:sWTi9ZWQW3KCPVNcegEIa+Ta+GM	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P00742	uniprotkb:Q9UK55	intact:EBI-719750|uniprotkb:Q14340|ensembl:ENSP00000364709	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:fa10_human(display_long)|uniprotkb:Stuart factor(gene name synonym)|uniprotkb:Stuart-Prower factor(gene name synonym)|uniprotkb:F10(gene name)|psi-mi:F10(display_short)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0400"(affinity technology)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22224303|imex:IM-27863-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000495.1|ensembl:ENSG00000126218(gene)|ensembl:ENST00000375559(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035972|interpro:IPR043504|mint:P00742|rcsb pdb:1C5M|rcsb pdb:1EZQ|rcsb pdb:1F0R|rcsb pdb:1F0S|rcsb pdb:1FAX|rcsb pdb:1FJS|rcsb pdb:1FXY|rcsb pdb:1G2L|rcsb pdb:1G2M|rcsb pdb:1HCG|rcsb pdb:1IOE|rcsb pdb:1IQE|rcsb pdb:1IQF|rcsb pdb:1IQG|rcsb pdb:1IQH|rcsb pdb:1IQI|rcsb pdb:1IQJ|rcsb pdb:1IQK|rcsb pdb:1IQL|rcsb pdb:1IQM|rcsb pdb:1IQN|rcsb pdb:1KSN|rcsb pdb:1LPG|rcsb pdb:1LPK|rcsb pdb:1LPZ|rcsb pdb:1LQD|rcsb pdb:1MQ5|rcsb pdb:1MQ6|rcsb pdb:1MSX|rcsb pdb:1NFU|rcsb pdb:1NFW|rcsb pdb:1NFX|rcsb pdb:1NFY|rcsb pdb:1NL8|rcsb pdb:1P0S|rcsb pdb:1V3X|rcsb pdb:1WU1|rcsb pdb:1XKA|rcsb pdb:1XKB|rcsb pdb:1Z6E|rcsb pdb:2BMG|rcsb pdb:2BOH|rcsb pdb:2BOK|rcsb pdb:2BQ6|rcsb pdb:2BQ7|rcsb pdb:2BQW|rcsb pdb:2CJI|rcsb pdb:2D1J|rcsb pdb:2EI6|rcsb pdb:2EI7|rcsb pdb:2EI8|rcsb pdb:2FZZ|rcsb pdb:2G00|rcsb pdb:2GD4|rcsb pdb:2H9E|rcsb pdb:2J2U|rcsb pdb:2J34|rcsb pdb:2J38|rcsb pdb:2J4I|rcsb pdb:2J94|rcsb pdb:2J95|rcsb pdb:2P16|rcsb pdb:2P3F|rcsb pdb:2P3T|rcsb pdb:2P3U|rcsb pdb:2P93|rcsb pdb:2P94|rcsb pdb:2P95|rcsb pdb:2PHB|rcsb pdb:2PR3|rcsb pdb:2Q1J|rcsb pdb:2RA0|rcsb pdb:2UWL|rcsb pdb:2UWO|rcsb pdb:2UWP|rcsb pdb:2VH0|rcsb pdb:2VH6|rcsb pdb:2VVC|rcsb pdb:2VVU|rcsb pdb:2VVV|rcsb pdb:2VWL|rcsb pdb:2VWM|rcsb pdb:2VWN|rcsb pdb:2VWO|rcsb pdb:2W26|rcsb pdb:2W3I|rcsb pdb:2W3K|rcsb pdb:2WYG|rcsb pdb:2WYJ|rcsb pdb:2XBV|rcsb pdb:2XBW|rcsb pdb:2XBX|rcsb pdb:2XBY|rcsb pdb:2XC0|rcsb pdb:2JKH|rcsb pdb:2XC4|rcsb pdb:2XC5|rcsb pdb:2Y5F|rcsb pdb:2Y5G|rcsb pdb:2Y5H|rcsb pdb:2Y7X|rcsb pdb:2Y7Z|rcsb pdb:2Y80|rcsb pdb:2Y81|rcsb pdb:2Y82|rcsb pdb:3CEN|rcsb pdb:3CS7|rcsb pdb:3ENS|rcsb pdb:3FFG|rcsb pdb:3HPT|rcsb pdb:3IIT|rcsb pdb:3K9X|rcsb pdb:3KL6|rcsb pdb:3KQB|rcsb pdb:3KQC|rcsb pdb:3KQD|rcsb pdb:3KQE|rcsb pdb:3LIW|rcsb pdb:3M36|rcsb pdb:3M37|rcsb pdb:3Q3K|rcsb pdb:3SW2|rcsb pdb:3TK6|rcsb pdb:4A7I|rcsb pdb:4BTI|rcsb pdb:4BTT|rcsb pdb:4BTU|rcsb pdb:4Y6D|rcsb pdb:4Y71|rcsb pdb:4Y76|rcsb pdb:4Y79|rcsb pdb:4Y7A|rcsb pdb:4Y7B|rcsb pdb:4ZH8|rcsb pdb:4ZHA|rcsb pdb:5JQY|rcsb pdb:5JTC|rcsb pdb:5JZ8|rcsb pdb:5JZU|rcsb pdb:5K0H|rcsb pdb:5VOE|rcsb pdb:5VOF|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6RK9|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|rcsb pdb:3TK5|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|refseq:NP_001299603.1|refseq:NP_001299604.1|dip:DIP-29896N	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	-	-	figure legend:Table 1-3, Figs. 5, 8|comment:In the presence of PROZ, lipid, and Ca2+ cofactors, there was a 10-fold reduction in F10-SERPINA10 binding for the F10 p.Glu334Ala mutant but the Glu404Ala mutant still had no effect.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/18	2019/11/18	rogid:EiG38fLKwrbGJftF5k4xjLvlYhA9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:sWTi9ZWQW3KCPVNcegEIa+Ta+GM	false	-	mutation with no effect:334-334|mutation with no effect:404-404|mutation with no effect:334-334,404-404|mutation with no effect:95-95,259-260,314-314|mutation decreasing interaction strength:408-408	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P03951-PRO_0000027825	uniprotkb:P03951-PRO_0000027826	intact:EBI-25507318	intact:EBI-25507345	psi-mi:p03951-pro_0000027825(display_long)|uniprotkb:F11(gene name)|psi-mi:F11(display_short)|uniprotkb:Plasma thromboplastin antecedent(gene name synonym)	psi-mi:p03951-pro_0000027826(display_long)|uniprotkb:F11(gene name)|psi-mi:F11(display_short)|uniprotkb:Plasma thromboplastin antecedent(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25507323|imex:IM-27863-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1041019(chain-parent)	intact:EBI-1041019(chain-parent)	-	chain-seq-start:19|chain-seq-end:387	chain-seq-start:388|chain-seq-end:625	figure legend:Table 2|comment:Carried out in the absence of cofactors.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.2x10^-5(molar)	2019/11/18	2020/04/14	rogid:F81n5bjCf98mrgUeoRV/i89g5Dw9606	rogid:gpfv2F42/b+GHFCkSTzc/UPNdhE9606	rigid:MJw3eAUC4ixME3BBouJ1zVzOFOc	false	binding-associated region:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P03951-PRO_0000027825	uniprotkb:Q9UK55	intact:EBI-25507318	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:p03951-pro_0000027825(display_long)|uniprotkb:F11(gene name)|psi-mi:F11(display_short)|uniprotkb:Plasma thromboplastin antecedent(gene name synonym)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0400"(affinity technology)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25507323|imex:IM-27863-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1041019(chain-parent)	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	chain-seq-start:19|chain-seq-end:387	-	figure legend:Table 2|comment:Carried out in the absence of cofactors.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.2x10^-5(molar)	2019/11/18	2020/04/14	rogid:F81n5bjCf98mrgUeoRV/i89g5Dw9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:MJw3eAUC4ixME3BBouJ1zVzOFOc	false	binding-associated region:?-?	mutation decreasing interaction strength:408-408	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22891	uniprotkb:Q9UK55	intact:EBI-22220337|uniprotkb:A6NMB4|uniprotkb:Q15213|uniprotkb:Q5JVF5|uniprotkb:Q5JVF6|ensembl:ENSP00000364697	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:proz_human(display_long)|uniprotkb:PROZ(gene name)|psi-mi:PROZ(display_short)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0400"(affinity technology)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22273709|imex:IM-27863-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243063.1|refseq:NP_003882.1|ensembl:ENSG00000126231(gene)|ensembl:ENST00000375547(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR035972|interpro:IPR043504|rcsb pdb:3F1S|rcsb pdb:3H5C|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	-	-	figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/18	2019/12/12	rogid:a3TU2GY7jzWdoqC2rQow8qraOaA9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:1j0+q7IHp0Bx22yajBp/S4aQZRY	false	sufficient binding region:84-400	mutation disrupting interaction strength:259-260,404-404,95-95|sufficient binding region:22-444	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22891	uniprotkb:Q9UK55	intact:EBI-22220337|uniprotkb:A6NMB4|uniprotkb:Q15213|uniprotkb:Q5JVF5|uniprotkb:Q5JVF6|ensembl:ENSP00000364697	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:proz_human(display_long)|uniprotkb:PROZ(gene name)|psi-mi:PROZ(display_short)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22304073|imex:IM-27863-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243063.1|refseq:NP_003882.1|ensembl:ENSG00000126231(gene)|ensembl:ENST00000375547(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR035972|interpro:IPR043504|rcsb pdb:3F1S|rcsb pdb:3H5C|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.0x10^-9(molar)	2019/11/18	2019/12/12	rogid:a3TU2GY7jzWdoqC2rQow8qraOaA9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:1j0+q7IHp0Bx22yajBp/S4aQZRY	false	sufficient binding region:84-400	sufficient binding region:22-444|mutation:402-402|fluorescent dye label:402-402	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22891	uniprotkb:Q9UK55	intact:EBI-22220337|uniprotkb:A6NMB4|uniprotkb:Q15213|uniprotkb:Q5JVF5|uniprotkb:Q5JVF6|ensembl:ENSP00000364697	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:proz_human(display_long)|uniprotkb:PROZ(gene name)|psi-mi:PROZ(display_short)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22304120|imex:IM-27863-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243063.1|refseq:NP_003882.1|ensembl:ENSG00000126231(gene)|ensembl:ENST00000375547(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR035972|interpro:IPR043504|rcsb pdb:3F1S|rcsb pdb:3H5C|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:5.0x10^-9(molar)	2019/11/18	2019/12/12	rogid:a3TU2GY7jzWdoqC2rQow8qraOaA9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:1j0+q7IHp0Bx22yajBp/S4aQZRY	false	sufficient binding region:84-400	sufficient binding region:22-444|mutation:143-143|fluorescent dye label:143-143	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22891	uniprotkb:Q9UK55	intact:EBI-22220337|uniprotkb:A6NMB4|uniprotkb:Q15213|uniprotkb:Q5JVF5|uniprotkb:Q5JVF6|ensembl:ENSP00000364697	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:proz_human(display_long)|uniprotkb:PROZ(gene name)|psi-mi:PROZ(display_short)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22304144|imex:IM-27863-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243063.1|refseq:NP_003882.1|ensembl:ENSG00000126231(gene)|ensembl:ENST00000375547(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR035972|interpro:IPR043504|rcsb pdb:3F1S|rcsb pdb:3H5C|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	-	-	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/18	2019/12/12	rogid:a3TU2GY7jzWdoqC2rQow8qraOaA9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:1j0+q7IHp0Bx22yajBp/S4aQZRY	false	sufficient binding region:84-400	sufficient binding region:22-444|mutation:402-402	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22891	uniprotkb:Q9UK55	intact:EBI-22220337|uniprotkb:A6NMB4|uniprotkb:Q15213|uniprotkb:Q5JVF5|uniprotkb:Q5JVF6|ensembl:ENSP00000364697	intact:EBI-3941758|uniprotkb:Q86U20|uniprotkb:A5Z2A5|uniprotkb:Q6UWX9|ensembl:ENSP00000261994|ensembl:ENSP00000376809|ensembl:ENSP00000450971|ensembl:ENSP00000484632	psi-mi:proz_human(display_long)|uniprotkb:PROZ(gene name)|psi-mi:PROZ(display_short)	psi-mi:zpi_human(display_long)|uniprotkb:SERPINA10(gene name)|psi-mi:SERPINA10(display_short)|uniprotkb:ZPI(gene name synonym)|uniprotkb:Serpin A10(gene name synonym)|uniprotkb:UNQ707/PRO1358(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Huang et al. (2010)	imex:IM-27863|pubmed:20427285	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22304157|imex:IM-27863-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243063.1|refseq:NP_003882.1|ensembl:ENSG00000126231(gene)|ensembl:ENST00000375547(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR035972|interpro:IPR043504|rcsb pdb:3F1S|rcsb pdb:3H5C|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782	ensembl:ENSG00000140093(gene)|ensembl:ENSG00000278767(gene)|ensembl:ENST00000261994(transcript)|ensembl:ENST00000393096(transcript)|ensembl:ENST00000554173(transcript)|ensembl:ENST00000614630(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR033835|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:3F1S|rcsb pdb:3H5C|rcsb pdb:4AFX|rcsb pdb:4AJU|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001094077.1|refseq:NP_057270.1|refseq:XP_005267790.1	-	-	-	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/18	2019/12/12	rogid:a3TU2GY7jzWdoqC2rQow8qraOaA9606	rogid:w0lFb4g2YwlRuSLWQWchQ4FwhlQ9606	rigid:1j0+q7IHp0Bx22yajBp/S4aQZRY	false	sufficient binding region:84-400	sufficient binding region:22-444|mutation:143-143	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)