#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:29105"	uniprotkb:P0A700	intact:EBI-968340	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	psi-mi:"zinc(2+)"(display_short)|psi-mi:"CHEBI:29105"(display_long)	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:"MI:0091"(chromatography technology)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230370|imex:IM-27918-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	-	-	-	figure legend:Table 1, Fig. 4|comment:Although the amount of zinc detected in HypA suggested that there were two zinc ions bound per dimer, 2 full equivalents were not detected immediately following purification. This ratio, however, was confirmed by incubation with several equivalents of zinc. Interaction observed by titrating with the metallochromic indicator PAR. Trace levels of Nickel were also observed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/28	2019/11/28	-	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	-	false	-	his tag:n-n	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A700	uniprotkb:P0A700	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:"MI:0091"(chromatography technology)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230441|imex:IM-27918-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	-	-	-	figure legend:Table 1|comment:Only low levels of zinc were observed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/28	2019/11/28	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	rigid:elGE4DXMcHVZlCVrUJSXs7Y1FN4	false	his tag:n-n	his tag:n-n	5	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:48828"	uniprotkb:P0A700	intact:EBI-22230464|chebi:"CHEBI:48827"|chebi:"CHEBI:23337"	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	psi-mi:"cobalt(2+)"(display_short)|psi-mi:"CHEBI:48828"(display_long)|intact:"Co(II)"(synonym)|intact:"Co(2+)"(synonym)|intact:Co2+(synonym)|intact:"COBALT (II) ION"(synonym)|intact:"Cobalt(2+)"(synonym)|intact:"cobalt(2+) ion"(synonym)|intact:"cobalt(II) cation"(synonym)|intact:cobaltous ion(synonym)|intact:"cobalt(II) cation"(iupac name)|intact:"cobalt(2+) ion"(iupac name)|intact:"cobalt(2+)"(iupac name)	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:"MI:0091"(chromatography technology)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230479|imex:IM-27918-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	-	-	-	figure legend:Table 1, Fig. 5|comment:A difference spectrum of cobalt-substituted HypA was generated by subtracting the spectrum of the zinc-containing HypA from the cobalt-loaded protein|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/28	2019/11/28	-	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	-	false	-	his tag:n-n	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A700	uniprotkb:P0A700	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:"MI:0071"(molecular sieving)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230454|imex:IM-27918-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	-	-	-	figure legend:Fig. 3|comment:Protein purified in the presence of EDTA|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/28	2019/11/28	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	rigid:elGE4DXMcHVZlCVrUJSXs7Y1FN4	false	his tag:n-n	his tag:n-n	5	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A700	uniprotkb:P0A700	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:"MI:0071"(molecular sieving)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230458|imex:IM-27918-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	-	-	-	figure legend:Fig. 3|comment:Protein purified in the presence of zinc|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/28	2019/11/28	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	rigid:elGE4DXMcHVZlCVrUJSXs7Y1FN4	false	his tag:n-n	his tag:n-n	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:29105"	uniprotkb:P0A700	intact:EBI-968340	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	psi-mi:"zinc(2+)"(display_short)|psi-mi:"CHEBI:29105"(display_long)	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230499|imex:IM-27918-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	-	-	-	figure legend:Fig. 6|comment:Kd was measured by titrating with the metallochromic indicator PAR.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:9.0x10^-10(molar)	2019/11/28	2019/11/28	-	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	-	false	-	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:49786"	uniprotkb:P0A700	intact:EBI-2296617	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	psi-mi:"nickel(2+)"(display_short)|psi-mi:"CHEBI:49786"(display_long)	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230529|imex:IM-27918-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	-	-	-	figure legend:Fig. 7|comment:Kd was measured by titrating with the metallochromic indicator PAR.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.3x10^-5(molar)	2019/11/28	2019/11/28	-	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	-	false	-	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AAN3	uniprotkb:P0A700	intact:EBI-558261|uniprotkb:P24190|uniprotkb:Q2MAA2|uniprotkb:Q46884|ensemblbacteria:AAC75769|ensemblbacteria:BAE76804	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	psi-mi:hypb_ecoli(display_long)|uniprotkb:hypB(gene name)|psi-mi:hypB(display_short)|uniprotkb:Hydrogenase isoenzymes nickel incorporation protein HypB(gene name synonym)|uniprotkb:JW2697(locus name)|uniprotkb:b2727(locus name)	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:"MI:0030"(cross-linking study)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230545|imex:IM-27918-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417207.1|refseq:WP_000337665.1|dip:DIP-36428N|ensemblbacteria:AAC75769(transcript)|ensemblbacteria:b2727(gene)|ensemblbacteria:BAE76804(gene)|ensemblbacteria:BAE76804(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0051604"(protein maturation)|interpro:IPR003495("Cobalamin (vitamin B12) biosynthesis CobW-like")|interpro:IPR004392(Hydrogenase accessory protein HypB)|interpro:IPR027417	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	-	-	-	figure legend:Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/28	2019/11/28	rogid:bg58XWiAv28fGfbHi898yF5HN8o83333	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	rigid:B2lmKy/pyh70l90VZyRfvOBBj6U	false	his tag:n-n	his tag:n-n	1	1	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P0AAN3	uniprotkb:P0AAN3	intact:EBI-558261|uniprotkb:P24190|uniprotkb:Q2MAA2|uniprotkb:Q46884|ensemblbacteria:AAC75769|ensemblbacteria:BAE76804	intact:EBI-558261|uniprotkb:P24190|uniprotkb:Q2MAA2|uniprotkb:Q46884|ensemblbacteria:AAC75769|ensemblbacteria:BAE76804	psi-mi:hypb_ecoli(display_long)|uniprotkb:hypB(gene name)|psi-mi:hypB(display_short)|uniprotkb:Hydrogenase isoenzymes nickel incorporation protein HypB(gene name synonym)|uniprotkb:JW2697(locus name)|uniprotkb:b2727(locus name)	psi-mi:hypb_ecoli(display_long)|uniprotkb:hypB(gene name)|psi-mi:hypB(display_short)|uniprotkb:Hydrogenase isoenzymes nickel incorporation protein HypB(gene name synonym)|uniprotkb:JW2697(locus name)|uniprotkb:b2727(locus name)	psi-mi:"MI:0030"(cross-linking study)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230558|imex:IM-27918-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417207.1|refseq:WP_000337665.1|dip:DIP-36428N|ensemblbacteria:AAC75769(transcript)|ensemblbacteria:b2727(gene)|ensemblbacteria:BAE76804(gene)|ensemblbacteria:BAE76804(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0051604"(protein maturation)|interpro:IPR003495("Cobalamin (vitamin B12) biosynthesis CobW-like")|interpro:IPR004392(Hydrogenase accessory protein HypB)|interpro:IPR027417	refseq:NP_417207.1|refseq:WP_000337665.1|dip:DIP-36428N|ensemblbacteria:AAC75769(transcript)|ensemblbacteria:b2727(gene)|ensemblbacteria:BAE76804(gene)|ensemblbacteria:BAE76804(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0051604"(protein maturation)|interpro:IPR003495("Cobalamin (vitamin B12) biosynthesis CobW-like")|interpro:IPR004392(Hydrogenase accessory protein HypB)|interpro:IPR027417	-	-	-	figure legend:Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/28	2019/11/28	rogid:bg58XWiAv28fGfbHi898yF5HN8o83333	rogid:bg58XWiAv28fGfbHi898yF5HN8o83333	rigid:QUALfHpUNoQTGaK3geFSvjW1XrQ	false	his tag:n-n	his tag:n-n	2	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0113"(western blot)
uniprotkb:P0A700	uniprotkb:P0A700	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	intact:EBI-6290024|ensemblbacteria:AAC75768|ensemblbacteria:BAE76803|uniprotkb:P24189|uniprotkb:Q2MAA3	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:hypa_ecoli(display_long)|uniprotkb:hypA(gene name)|psi-mi:hypA(display_short)|uniprotkb:b2726(locus name)|uniprotkb:JW2696(locus name)	psi-mi:"MI:0030"(cross-linking study)	Atanassova et al. (2005)	imex:IM-27918|pubmed:15995183	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22230563|imex:IM-27918-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	ensemblbacteria:AAC75768(transcript)|ensemblbacteria:b2726(gene)|ensemblbacteria:BAE76803(gene)|ensemblbacteria:BAE76803(transcript)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016151"(nickel cation binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR000688(Hydrogenase expression/synthesis, HypA)|interpro:IPR020538|refseq:WP_001299100.1|dip:DIP-48022N|refseq:NP_417206.1	-	-	-	figure legend:Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/28	2019/11/28	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	rogid:Ean6OfcE8MFqbj2442Oswl0KWBA83333	rigid:elGE4DXMcHVZlCVrUJSXs7Y1FN4	false	his tag:n-n	his tag:n-n	2	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)