#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P08069	uniprotkb:P05556-1	intact:EBI-475981|uniprotkb:Q14CV2|uniprotkb:B1B5Y2|uniprotkb:Q9UCC0|ensembl:ENSP00000497069	intact:EBI-6082935|intact:EBI-8610683|intact:MINT-140124|intact:EBI-8610426|intact:EBI-8610873|intact:EBI-8611331|intact:EBI-8610721|intact:EBI-8611781|intact:EBI-8612236|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444	psi-mi:igf1r_human(display_long)|uniprotkb:Insulin-like growth factor I receptor(gene name synonym)|uniprotkb:IGF1R(gene name)|psi-mi:IGF1R(display_short)	psi-mi:p05556-1(display_long)|uniprotkb:Glycoprotein IIa(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:Beta-1A(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Goel et al. (2004)	pubmed:15289498|imex:IM-27093	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21454941|imex:IM-27093-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000866.1|ensembl:ENSG00000140443(gene)|ensembl:ENST00000650285(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005009"(insulin-activated receptor activity)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0043560"(insulin receptor substrate binding)|rcsb pdb:1JQH|go:"GO:0006955"(immune response)|refseq:NP_001278787.1|dip:DIP-476N|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035867"(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043559"(insulin binding)|go:"GO:0045056"(transcytosis)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051389"(obsolete inactivation of MAPKK activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140318"(protein transporter activity)|go:"GO:1902911"(protein kinase complex)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016246(Insulin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036941|mint:P08069|rcsb pdb:1IGR|rcsb pdb:1K3A|rcsb pdb:1M7N|rcsb pdb:1P4O|rcsb pdb:2OJ9|rcsb pdb:2ZM3|rcsb pdb:3D94|rcsb pdb:3F5P|rcsb pdb:3I81|rcsb pdb:3LVP|rcsb pdb:3LW0|rcsb pdb:3NW5|rcsb pdb:3NW6|rcsb pdb:3NW7|rcsb pdb:3O23|rcsb pdb:3QQU|rcsb pdb:4D2R|rcsb pdb:4XSS|rcsb pdb:5FXQ|rcsb pdb:5FXR|rcsb pdb:5FXS|rcsb pdb:5HZN|rcsb pdb:5U8R|rcsb pdb:6JK8|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|reactome:R-HSA-2404192|reactome:R-HSA-2428928|reactome:R-HSA-2428933|reactome:R-HSA-9009391|rcsb pdb:5U8Q	intact:EBI-703066(isoform-parent)|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)	-	-	-	figure legend:Fig. 6D, Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2019/06/19	2019/06/19	rogid:5RlIkDngFFJ/IO9tyZQnh1Riz0s9606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rigid:g1mfxxaED9SewbW8nqYbbkc/NyM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08069	uniprotkb:P05556-3	intact:EBI-475981|uniprotkb:Q14CV2|uniprotkb:B1B5Y2|uniprotkb:Q9UCC0|ensembl:ENSP00000497069	intact:EBI-21454988|ensembl:ENSP00000503538|ensembl:ENSP00000504508	psi-mi:igf1r_human(display_long)|uniprotkb:Insulin-like growth factor I receptor(gene name synonym)|uniprotkb:IGF1R(gene name)|psi-mi:IGF1R(display_short)	psi-mi:p05556-3(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:Beta-1C(isoform synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Goel et al. (2004)	pubmed:15289498|imex:IM-27093	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21454980|imex:IM-27093-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000866.1|ensembl:ENSG00000140443(gene)|ensembl:ENST00000650285(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005009"(insulin-activated receptor activity)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0043560"(insulin receptor substrate binding)|rcsb pdb:1JQH|go:"GO:0006955"(immune response)|refseq:NP_001278787.1|dip:DIP-476N|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035867"(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043559"(insulin binding)|go:"GO:0045056"(transcytosis)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051389"(obsolete inactivation of MAPKK activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140318"(protein transporter activity)|go:"GO:1902911"(protein kinase complex)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016246(Insulin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036941|mint:P08069|rcsb pdb:1IGR|rcsb pdb:1K3A|rcsb pdb:1M7N|rcsb pdb:1P4O|rcsb pdb:2OJ9|rcsb pdb:2ZM3|rcsb pdb:3D94|rcsb pdb:3F5P|rcsb pdb:3I81|rcsb pdb:3LVP|rcsb pdb:3LW0|rcsb pdb:3NW5|rcsb pdb:3NW6|rcsb pdb:3NW7|rcsb pdb:3O23|rcsb pdb:3QQU|rcsb pdb:4D2R|rcsb pdb:4XSS|rcsb pdb:5FXQ|rcsb pdb:5FXR|rcsb pdb:5FXS|rcsb pdb:5HZN|rcsb pdb:5U8R|rcsb pdb:6JK8|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|reactome:R-HSA-2404192|reactome:R-HSA-2428928|reactome:R-HSA-2428933|reactome:R-HSA-9009391|rcsb pdb:5U8Q	intact:EBI-703066(isoform-parent)|ensembl:ENSG00000150093(gene)|ensembl:ENST00000677310(transcript)|ensembl:ENST00000678766(transcript)	-	-	-	figure legend:Fig. 6D, Fig. 7A|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2019/06/19	2019/06/19	rogid:5RlIkDngFFJ/IO9tyZQnh1Riz0s9606	rogid:0fUaFE/P52gVW+b4PQdZ3gKguTo9606	rigid:OvOnSvCAvxGBcCd59pJ3myiRH1U	false	-	mutation causing an interaction:802-825|sufficient binding region:1-801	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08069	uniprotkb:P05556	intact:EBI-475981|uniprotkb:Q14CV2|uniprotkb:B1B5Y2|uniprotkb:Q9UCC0|ensembl:ENSP00000497069	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:igf1r_human(display_long)|uniprotkb:Insulin-like growth factor I receptor(gene name synonym)|uniprotkb:IGF1R(gene name)|psi-mi:IGF1R(display_short)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Goel et al. (2004)	pubmed:15289498|imex:IM-27093	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21455008|imex:IM-27093-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000866.1|ensembl:ENSG00000140443(gene)|ensembl:ENST00000650285(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005009"(insulin-activated receptor activity)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0043560"(insulin receptor substrate binding)|rcsb pdb:1JQH|go:"GO:0006955"(immune response)|refseq:NP_001278787.1|dip:DIP-476N|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035867"(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043559"(insulin binding)|go:"GO:0045056"(transcytosis)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051389"(obsolete inactivation of MAPKK activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140318"(protein transporter activity)|go:"GO:1902911"(protein kinase complex)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016246(Insulin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036941|mint:P08069|rcsb pdb:1IGR|rcsb pdb:1K3A|rcsb pdb:1M7N|rcsb pdb:1P4O|rcsb pdb:2OJ9|rcsb pdb:2ZM3|rcsb pdb:3D94|rcsb pdb:3F5P|rcsb pdb:3I81|rcsb pdb:3LVP|rcsb pdb:3LW0|rcsb pdb:3NW5|rcsb pdb:3NW6|rcsb pdb:3NW7|rcsb pdb:3O23|rcsb pdb:3QQU|rcsb pdb:4D2R|rcsb pdb:4XSS|rcsb pdb:5FXQ|rcsb pdb:5FXR|rcsb pdb:5FXS|rcsb pdb:5HZN|rcsb pdb:5U8R|rcsb pdb:6JK8|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|reactome:R-HSA-2404192|reactome:R-HSA-2428928|reactome:R-HSA-2428933|reactome:R-HSA-9009391|rcsb pdb:5U8Q	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191	-	-	-	figure legend:Fig. 6D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2019/06/19	2019/06/19	rogid:5RlIkDngFFJ/IO9tyZQnh1Riz0s9606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rigid:g1mfxxaED9SewbW8nqYbbkc/NyM	false	-	sufficient binding region:1-777	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A0A3L7I1U0	uniprotkb:P05556-3	intact:EBI-21455058	intact:EBI-21454988|ensembl:ENSP00000503538|ensembl:ENSP00000504508	psi-mi:a0a3l7i1u0_crigr(display_long)|uniprotkb:CgPICR_020130(orf name)	psi-mi:p05556-3(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:Beta-1C(isoform synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Goel et al. (2004)	pubmed:15289498|imex:IM-27093	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21455019|imex:IM-27093-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)	intact:EBI-703066(isoform-parent)|ensembl:ENSG00000150093(gene)|ensembl:ENST00000677310(transcript)|ensembl:ENST00000678766(transcript)	-	-	-	figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2019/06/19	2019/06/19	rogid:6gifWbTzQjsVCaNxjtXJ5GlKrUs10029	rogid:0fUaFE/P52gVW+b4PQdZ3gKguTo9606	rigid:fglPz8OmeIjLwItbZMb25mBPdpY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:G3I658	uniprotkb:P05556-1	intact:EBI-21455072|ensembl:ENSCGRP00001013475|ensembl:ENSCGRP00015014025	intact:EBI-6082935|intact:EBI-8610683|intact:MINT-140124|intact:EBI-8610426|intact:EBI-8610873|intact:EBI-8611331|intact:EBI-8610721|intact:EBI-8611781|intact:EBI-8612236|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444	psi-mi:g3i658_crigr(display_long)|uniprotkb:CgPICR_017317(orf name)|uniprotkb:I79_018970(orf name)	psi-mi:p05556-1(display_long)|uniprotkb:Glycoprotein IIa(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:Beta-1A(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Goel et al. (2004)	pubmed:15289498|imex:IM-27093	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21455066|imex:IM-27093-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_007649442.1|ensembl:ENSCGRG00001014601(gene)|ensembl:ENSCGRG00015010788(gene)|ensembl:ENSCGRT00001017712(transcript)|ensembl:ENSCGRT00015017175(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011	intact:EBI-703066(isoform-parent)|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)	-	-	-	figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2019/06/19	2019/06/19	rogid:nKc3r+H8ShWFwTXf1z7vZPfgOgk10029	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rigid:/wswWkoitfW3Xwi61AAoopSUxSA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A0A3L7I1U0	intact:EBI-21455102	intact:EBI-21455058	-	psi-mi:a0a3l7i1u0_crigr(display_long)|uniprotkb:CgPICR_020130(orf name)	psi-mi:ptn11_crigr_protein(display_short)|psi-mi:EBI-21455102(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Goel et al. (2004)	pubmed:15289498|imex:IM-27093	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21455086|imex:IM-27093-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)	-	-	-	comment:similar to human UniProt Q06124	figure legend:Fig. 7E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2019/06/19	2019/06/19	rogid:6gifWbTzQjsVCaNxjtXJ5GlKrUs10029	-	-	false	-	O4'-phospho-L-tyrosine:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A0A3L7I1U0	uniprotkb:P05556-1	intact:EBI-21455058	intact:EBI-6082935|intact:EBI-8610683|intact:MINT-140124|intact:EBI-8610426|intact:EBI-8610873|intact:EBI-8611331|intact:EBI-8610721|intact:EBI-8611781|intact:EBI-8612236|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444	psi-mi:a0a3l7i1u0_crigr(display_long)|uniprotkb:CgPICR_020130(orf name)	psi-mi:p05556-1(display_long)|uniprotkb:Glycoprotein IIa(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:Beta-1A(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Goel et al. (2004)	pubmed:15289498|imex:IM-27093	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21455086|imex:IM-27093-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)	intact:EBI-703066(isoform-parent)|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)	-	-	-	figure legend:Fig. 7E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2019/06/19	2019/06/19	rogid:6gifWbTzQjsVCaNxjtXJ5GlKrUs10029	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	-	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08069-PRO_0000016682	uniprotkb:P05556-1	intact:EBI-22054038	intact:EBI-6082935|intact:EBI-8610683|intact:MINT-140124|intact:EBI-8610426|intact:EBI-8610873|intact:EBI-8611331|intact:EBI-8610721|intact:EBI-8611781|intact:EBI-8612236|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444	psi-mi:p08069-pro_0000016682(display_long)|uniprotkb:Insulin-like growth factor I receptor(gene name synonym)|uniprotkb:IGF1R(gene name)|psi-mi:IGF1R(display_short)	psi-mi:p05556-1(display_long)|uniprotkb:Glycoprotein IIa(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:Beta-1A(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Goel et al. (2004)	pubmed:15289498|imex:IM-27093	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22054032|imex:IM-27093-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-475981(chain-parent)	intact:EBI-703066(isoform-parent)|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)	-	chain-seq-start:741|chain-seq-end:1367	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-pc3)|taxid:9606(Human PC3 Caucasian prostate adenocarcinoma)	-	2019/06/19	2019/09/27	rogid:+53U5n/aRfkfMdAsqsYgGE1hznM9606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rigid:kedS6FWqEtIEeBNngu+DF/lTD3E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08069-PRO_0000016682	uniprotkb:P05556	intact:EBI-22054038	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:p08069-pro_0000016682(display_long)|uniprotkb:Insulin-like growth factor I receptor(gene name synonym)|uniprotkb:IGF1R(gene name)|psi-mi:IGF1R(display_short)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Goel et al. (2004)	pubmed:15289498|imex:IM-27093	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22054060|imex:IM-27093-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-475981(chain-parent)	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191	-	chain-seq-start:741|chain-seq-end:1367	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-pc3)|taxid:9606(Human PC3 Caucasian prostate adenocarcinoma)	-	2019/06/19	2019/09/27	rogid:+53U5n/aRfkfMdAsqsYgGE1hznM9606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rigid:kedS6FWqEtIEeBNngu+DF/lTD3E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)