#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y5B0 uniprotkb:P35269 intact:EBI-2807555|ensembl:ENSP00000484525|uniprotkb:Q9Y6F5|uniprotkb:Q7Z644|uniprotkb:Q96BZ1|uniprotkb:A8MY97 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 psi-mi:ctdp1_human(display_long)|uniprotkb:CTDP1(gene name)|psi-mi:CTDP1(display_short)|uniprotkb:FCP1(gene name synonym)|uniprotkb:TFIIF-associating CTD phosphatase(gene name synonym) psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Nguyen et al. (2003) pubmed:12732728|imex:IM-27421 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-21943541|imex:IM-27421-1|pdbe:1onv - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000060069(gene)|ensembl:ENST00000613122(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0030496"(midbody)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR001357(BRCT)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011947(FCP1-like phosphatase, phosphatase domain)|interpro:IPR015388(FCP1-like phosphatase, C-terminal)|interpro:IPR023214|interpro:IPR036412|interpro:IPR036420|interpro:IPR039189|rcsb pdb:1J2X|rcsb pdb:1ONV|rcsb pdb:2K7L|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_001189433.1|refseq:NP_004706.3|refseq:NP_430255.2|dip:DIP-41788N go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N - - - figure legend:Fig.1-3, table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/07/30 2019/07/30 rogid:LEqMeYJjhIWOx3RZtX3ljR5IZS49606 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 rigid:NudPeuTE2mpioZgsznOm4VmMWaw false sufficient binding region:945-961|13c label:?-?|15n label:?-? sufficient binding region:451-517|13c label:?-?|15n label:?-? 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35269 uniprotkb:Q9Y5B0 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 intact:EBI-2807555|ensembl:ENSP00000484525|uniprotkb:Q9Y6F5|uniprotkb:Q7Z644|uniprotkb:Q96BZ1|uniprotkb:A8MY97 psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:ctdp1_human(display_long)|uniprotkb:CTDP1(gene name)|psi-mi:CTDP1(display_short)|uniprotkb:FCP1(gene name synonym)|uniprotkb:TFIIF-associating CTD phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) Nguyen et al. (2003) pubmed:12732728|imex:IM-27421 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-21943575|imex:IM-27421-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N ensembl:ENSG00000060069(gene)|ensembl:ENST00000613122(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0030496"(midbody)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR001357(BRCT)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011947(FCP1-like phosphatase, phosphatase domain)|interpro:IPR015388(FCP1-like phosphatase, C-terminal)|interpro:IPR023214|interpro:IPR036412|interpro:IPR036420|interpro:IPR039189|rcsb pdb:1J2X|rcsb pdb:1ONV|rcsb pdb:2K7L|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_001189433.1|refseq:NP_004706.3|refseq:NP_430255.2|dip:DIP-41788N - - - figure legend:Fig.4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/07/30 2019/07/30 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 rogid:LEqMeYJjhIWOx3RZtX3ljR5IZS49606 rigid:NudPeuTE2mpioZgsznOm4VmMWaw false sufficient binding region:436-517 glutathione s tranferase tag:?-?|sufficient binding region:879-961|mutation decreasing interaction:956-957 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)