#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9TU32 uniprotkb:Q8NI22 intact:EBI-25399342 intact:EBI-2689785|uniprotkb:Q8N3M5|uniprotkb:Q53SS3|uniprotkb:A8K7W2|uniprotkb:E9PD95|uniprotkb:Q68D61|uniprotkb:D6W5A9|ensembl:ENSP00000317271|ensembl:ENSP00000386261|ensembl:ENSP00000386279|ensembl:ENSP00000386386|ensembl:ENSP00000386651|ensembl:ENSP00000402717 psi-mi:lman1_chlae(display_long)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym) psi-mi:mcfd2_human(display_long)|uniprotkb:SDNSF(gene name synonym)|uniprotkb:Neural stem cell-derived neuronal survival protein(gene name synonym)|uniprotkb:MCFD2(gene name)|psi-mi:MCFD2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2003) pubmed:12717434|imex:IM-27366 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-22050722|imex:IM-27366-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR005052(Legume-like lectin)|interpro:IPR033085|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding) refseq:NP_001164977.1|refseq:NP_001164978.1|refseq:NP_001164979.1|refseq:NP_001164980.1|refseq:NP_001164981.1|refseq:NP_001164982.1|refseq:NP_644808.1|ensembl:ENSG00000180398(gene)|ensembl:ENST00000319466(transcript)|ensembl:ENST00000409105(transcript)|ensembl:ENST00000409207(transcript)|ensembl:ENST00000409218(transcript)|ensembl:ENST00000409973(transcript)|ensembl:ENST00000412438(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:2VRG|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-948021|dip:DIP-56233N - - - figure legend:Figure 5|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2019/09/24 2020/01/17 rogid:Kp1xrlqkvhzEuVoXF9Y0C+azcWI9534 rogid:Sq83HLKrA00mHO758Ib/PsAd1kc9606 rigid:C9yH4AhbRkTkdL1tGdf6zd8Hwrs false - mutation disrupting interaction strength:136-136|mutation decreasing interaction strength:136-136|myc tag:?-?|mutation disrupting interaction strength:129-129|35s radiolabel:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-25399399 uniprotkb:Q9TU32 - intact:EBI-25399342 psi-mi:mcfd2(display_short)|psi-mi:EBI-25399399(display_long) psi-mi:lman1_chlae(display_long)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2003) pubmed:12717434|imex:IM-27366 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25399396|imex:IM-27366-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8NI22(see-also) interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR005052(Legume-like lectin)|interpro:IPR033085|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding) - - - figure legend:Fig. 5|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2019/09/24 2020/01/17 - rogid:Kp1xrlqkvhzEuVoXF9Y0C+azcWI9534 - false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9TU32 uniprotkb:Q8NI22 intact:EBI-25399342 intact:EBI-2689785|uniprotkb:Q8N3M5|uniprotkb:Q53SS3|uniprotkb:A8K7W2|uniprotkb:E9PD95|uniprotkb:Q68D61|uniprotkb:D6W5A9|ensembl:ENSP00000317271|ensembl:ENSP00000386261|ensembl:ENSP00000386279|ensembl:ENSP00000386386|ensembl:ENSP00000386651|ensembl:ENSP00000402717 psi-mi:lman1_chlae(display_long)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym) psi-mi:mcfd2_human(display_long)|uniprotkb:SDNSF(gene name synonym)|uniprotkb:Neural stem cell-derived neuronal survival protein(gene name synonym)|uniprotkb:MCFD2(gene name)|psi-mi:MCFD2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2003) pubmed:12717434|imex:IM-27366 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25766312|imex:IM-27366-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR005052(Legume-like lectin)|interpro:IPR033085|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding) refseq:NP_001164977.1|refseq:NP_001164978.1|refseq:NP_001164979.1|refseq:NP_001164980.1|refseq:NP_001164981.1|refseq:NP_001164982.1|refseq:NP_644808.1|ensembl:ENSG00000180398(gene)|ensembl:ENST00000319466(transcript)|ensembl:ENST00000409105(transcript)|ensembl:ENST00000409207(transcript)|ensembl:ENST00000409218(transcript)|ensembl:ENST00000409973(transcript)|ensembl:ENST00000412438(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:2VRG|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-948021|dip:DIP-56233N - - - figure legend:Figure 5|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2019/09/24 2020/08/03 rogid:Kp1xrlqkvhzEuVoXF9Y0C+azcWI9534 rogid:Sq83HLKrA00mHO758Ib/PsAd1kc9606 rigid:C9yH4AhbRkTkdL1tGdf6zd8Hwrs false - mutation disrupting interaction strength:136-136|mutation decreasing interaction strength:136-136|myc tag:?-?|mutation disrupting interaction strength:129-129|35s radiolabel:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)