#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P14621 uniprotkb:P14621 intact:EBI-10198377|ensembl:ENSP00000378161 intact:EBI-10198377|ensembl:ENSP00000378161 psi-mi:acyp2_human(display_long)|uniprotkb:ACYP2(gene name)|psi-mi:ACYP2(display_short)|uniprotkb:ACYP(gene name synonym)|uniprotkb:Acylphosphatase, muscle type isozyme(gene name synonym)|uniprotkb:Acylphosphate phosphohydrolase 2(gene name synonym) psi-mi:acyp2_human(display_long)|uniprotkb:ACYP2(gene name)|psi-mi:ACYP2(display_short)|uniprotkb:ACYP(gene name synonym)|uniprotkb:Acylphosphatase, muscle type isozyme(gene name synonym)|uniprotkb:Acylphosphate phosphohydrolase 2(gene name synonym) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Chiti et al. (2002) pubmed:12374855|imex:IM-27412 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-22079385|imex:IM-27412-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612457.1|ensembl:ENSG00000170634(gene)|ensembl:ENST00000394666(transcript)|go:"GO:0003998"(acylphosphatase activity)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR001792(Acylphosphatase)|interpro:IPR017968|interpro:IPR020456|interpro:IPR036046|dip:DIP-48449N refseq:NP_612457.1|ensembl:ENSG00000170634(gene)|ensembl:ENST00000394666(transcript)|go:"GO:0003998"(acylphosphatase activity)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR001792(Acylphosphatase)|interpro:IPR017968|interpro:IPR020456|interpro:IPR036046|dip:DIP-48449N - - - figure legend:Table 1, Fig. 3A|comment:Fig.3a describes the increase of ThT fluorescence resulting from aggregation of wild-type AcP and some representative mutants under these conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/10/07 2019/10/14 rogid:k5waNYAUowKldZHlWsCBsuSN9n89606 rogid:k5waNYAUowKldZHlWsCBsuSN9n89606 rigid:W0GQ7UX5Vl6ZhLcCS4SeDdc+s1Q false mutation decreasing interaction strength:30-30|mutation decreasing interaction strength:30-30|mutation decreasing interaction strength:30-30|mutation with no effect:9-9|mutation with no effect:56-56|mutation with no effect:98-98|mutation increasing interaction strength:24-24|mutation increasing interaction strength:44-44|mutation increasing interaction strength:78-78|mutation decreasing interaction strength:89-89|mutation decreasing interaction strength:89-89|mutation decreasing interaction strength:91-91|mutation decreasing interaction strength:93-93|mutation increasing interaction strength:98-98 mutation decreasing interaction strength:30-30|mutation decreasing interaction strength:30-30|mutation decreasing interaction strength:30-30|mutation with no effect:9-9|mutation with no effect:56-56|mutation with no effect:98-98|mutation increasing interaction strength:24-24|mutation increasing interaction strength:44-44|mutation increasing interaction strength:78-78|mutation decreasing interaction strength:89-89|mutation decreasing interaction strength:89-89|mutation decreasing interaction strength:91-91|mutation decreasing interaction strength:93-93|mutation increasing interaction strength:98-98 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)