#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UHC1	uniprotkb:P40692	intact:EBI-3893094|uniprotkb:P49751|uniprotkb:Q56DK9|uniprotkb:Q9P292|uniprotkb:Q9UHC0|ensembl:ENSP00000348020	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:mlh3_human(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0916"(lexa vp16 complementation)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267047|imex:IM-27543-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016876708.1|refseq:XP_006720179.1|refseq:NP_001035197.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005712"(chiasma)|go:"GO:0006298"(mismatch repair)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007144"(female meiosis I)|go:"GO:0008104"(protein localization)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|reactome:R-HSA-912446|ensembl:ENSG00000119684(gene)|ensembl:ENST00000355774(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	-	-	-	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/12/04	2019/12/04	rogid:8FpSX4YxQWxM9HBykG4bJME7HzQ9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:Vh8KQeZs8OGxkZ/p+BfX5eEp9bs	false	-	necessary binding region:695-756|sufficient binding region:492-742(IPR032189)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54277	uniprotkb:P40692	intact:EBI-2893308|ensembl:ENSP00000406490|uniprotkb:D3DPI1|uniprotkb:Q4VAL4|uniprotkb:Q5FBZ8|uniprotkb:Q5FBZ3|uniprotkb:Q5FBZ6	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:pms1_human(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:PMSL1(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS1(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0916"(lexa vp16 complementation)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267057|imex:IM-27543-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000525.1|ensembl:ENSG00000064933(gene)|ensembl:ENST00000441310(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR036910|interpro:IPR038973|mint:P54277|rcsb pdb:2CS1|refseq:NP_001276337.1|refseq:XP_016859833.1|refseq:XP_016859837.1|refseq:NP_001121616.1|refseq:NP_001121615.1|refseq:NP_001307974.1|refseq:NP_001307975.1|refseq:NP_001307976.1|refseq:NP_001307977.1	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	-	-	-	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/12/04	2019/12/04	rogid:URnCj+2/Inh5Wsc1UFHYh1gowFQ9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:ljeIUHcYUPkX13gD2L/B7Yp9JlE	false	-	necessary binding region:695-756|sufficient binding region:492-742(IPR032189)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54278	uniprotkb:P40692	intact:EBI-1162561|uniprotkb:Q5FBW9|uniprotkb:Q5FBX1|uniprotkb:Q5FBX2|uniprotkb:Q52LH6|uniprotkb:Q75MR2|uniprotkb:B2R610|ensembl:ENSP00000265849	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:pms2_human(display_long)|uniprotkb:PMS1 protein homolog 2(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS2(gene name synonym)|uniprotkb:PMS2(gene name)|psi-mi:PMS2(display_short)|uniprotkb:PMSL2(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0916"(lexa vp16 complementation)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267065|imex:IM-27543-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000122512(gene)|ensembl:ENST00000265849(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006298"(mismatch repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0032138"(single base insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|mint:P54278|rcsb pdb:1H7S|rcsb pdb:1H7U|rcsb pdb:5U5R|rcsb pdb:6MFQ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|rcsb pdb:1EA6|refseq:NP_000526.2|refseq:NP_001308932.1|refseq:NP_001308933.1|refseq:NP_001308934.1|refseq:NP_001308935.1|refseq:NP_001308936.1|refseq:NP_001308937.1|refseq:NP_001308938.1|refseq:NP_001308939.1|refseq:NP_001308940.1|refseq:NP_001308941.1|refseq:NP_001308942.1|refseq:NP_001308943.1|refseq:NP_001308944.1|refseq:XP_016885888.1|dip:DIP-46295N	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	-	-	-	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/12/04	2019/12/04	rogid:ZEPZOzJgtNSaYyRonkvr/+/30AE9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:V+h9QsGaEB7a1kNJz2tPPj4Yzzw	false	-	necessary binding region:695-756|sufficient binding region:492-742(IPR032189)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54278	uniprotkb:P40692	intact:EBI-1162561|uniprotkb:Q5FBW9|uniprotkb:Q5FBX1|uniprotkb:Q5FBX2|uniprotkb:Q52LH6|uniprotkb:Q75MR2|uniprotkb:B2R610|ensembl:ENSP00000265849	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:pms2_human(display_long)|uniprotkb:PMS1 protein homolog 2(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS2(gene name synonym)|uniprotkb:PMS2(gene name)|psi-mi:PMS2(display_short)|uniprotkb:PMSL2(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0916"(lexa vp16 complementation)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267073|imex:IM-27543-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000122512(gene)|ensembl:ENST00000265849(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006298"(mismatch repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0032138"(single base insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|mint:P54278|rcsb pdb:1H7S|rcsb pdb:1H7U|rcsb pdb:5U5R|rcsb pdb:6MFQ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|rcsb pdb:1EA6|refseq:NP_000526.2|refseq:NP_001308932.1|refseq:NP_001308933.1|refseq:NP_001308934.1|refseq:NP_001308935.1|refseq:NP_001308936.1|refseq:NP_001308937.1|refseq:NP_001308938.1|refseq:NP_001308939.1|refseq:NP_001308940.1|refseq:NP_001308941.1|refseq:NP_001308942.1|refseq:NP_001308943.1|refseq:NP_001308944.1|refseq:XP_016885888.1|dip:DIP-46295N	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	-	-	-	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/12/04	2019/12/04	rogid:ZEPZOzJgtNSaYyRonkvr/+/30AE9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:V+h9QsGaEB7a1kNJz2tPPj4Yzzw	false	sufficient binding region:612-647|necessary binding region:612-625	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54277	uniprotkb:P40692	intact:EBI-2893308|ensembl:ENSP00000406490|uniprotkb:D3DPI1|uniprotkb:Q4VAL4|uniprotkb:Q5FBZ8|uniprotkb:Q5FBZ3|uniprotkb:Q5FBZ6	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:pms1_human(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:PMSL1(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS1(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0916"(lexa vp16 complementation)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267190|imex:IM-27543-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000525.1|ensembl:ENSG00000064933(gene)|ensembl:ENST00000441310(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR036910|interpro:IPR038973|mint:P54277|rcsb pdb:2CS1|refseq:NP_001276337.1|refseq:XP_016859833.1|refseq:XP_016859837.1|refseq:NP_001121616.1|refseq:NP_001121615.1|refseq:NP_001307974.1|refseq:NP_001307975.1|refseq:NP_001307976.1|refseq:NP_001307977.1	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	-	-	-	figure legend:Fig. 4, Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/12/04	2019/12/04	rogid:URnCj+2/Inh5Wsc1UFHYh1gowFQ9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:ljeIUHcYUPkX13gD2L/B7Yp9JlE	false	necessary binding region:693-728|sufficient binding region:693-728	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHC1	uniprotkb:P40692	intact:EBI-3893094|uniprotkb:P49751|uniprotkb:Q56DK9|uniprotkb:Q9P292|uniprotkb:Q9UHC0|ensembl:ENSP00000348020	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:mlh3_human(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0916"(lexa vp16 complementation)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267202|imex:IM-27543-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016876708.1|refseq:XP_006720179.1|refseq:NP_001035197.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005712"(chiasma)|go:"GO:0006298"(mismatch repair)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007144"(female meiosis I)|go:"GO:0008104"(protein localization)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|reactome:R-HSA-912446|ensembl:ENSG00000119684(gene)|ensembl:ENST00000355774(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	-	-	-	figure legend:Fig. 4, Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/12/04	2019/12/04	rogid:8FpSX4YxQWxM9HBykG4bJME7HzQ9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:Vh8KQeZs8OGxkZ/p+BfX5eEp9bs	false	sufficient binding region:860-895|sufficient binding region:1399-1453	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54278	uniprotkb:P40692	intact:EBI-1162561|uniprotkb:Q5FBW9|uniprotkb:Q5FBX1|uniprotkb:Q5FBX2|uniprotkb:Q52LH6|uniprotkb:Q75MR2|uniprotkb:B2R610|ensembl:ENSP00000265849	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:pms2_human(display_long)|uniprotkb:PMS1 protein homolog 2(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS2(gene name synonym)|uniprotkb:PMS2(gene name)|psi-mi:PMS2(display_short)|uniprotkb:PMSL2(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267095|imex:IM-27543-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000122512(gene)|ensembl:ENST00000265849(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006298"(mismatch repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0032138"(single base insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|mint:P54278|rcsb pdb:1H7S|rcsb pdb:1H7U|rcsb pdb:5U5R|rcsb pdb:6MFQ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|rcsb pdb:1EA6|refseq:NP_000526.2|refseq:NP_001308932.1|refseq:NP_001308933.1|refseq:NP_001308934.1|refseq:NP_001308935.1|refseq:NP_001308936.1|refseq:NP_001308937.1|refseq:NP_001308938.1|refseq:NP_001308939.1|refseq:NP_001308940.1|refseq:NP_001308941.1|refseq:NP_001308942.1|refseq:NP_001308943.1|refseq:NP_001308944.1|refseq:XP_016885888.1|dip:DIP-46295N	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	-	-	-	figure legend:Fig. 2, Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hec1a)|taxid:9606(Homo sapiens)	-	2019/12/04	2019/12/04	rogid:ZEPZOzJgtNSaYyRonkvr/+/30AE9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:V+h9QsGaEB7a1kNJz2tPPj4Yzzw	false	sufficient binding region:612-674|necessary binding region:612-625|flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40692	uniprotkb:P54278	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-1162561|uniprotkb:Q5FBW9|uniprotkb:Q5FBX1|uniprotkb:Q5FBX2|uniprotkb:Q52LH6|uniprotkb:Q75MR2|uniprotkb:B2R610|ensembl:ENSP00000265849	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:pms2_human(display_long)|uniprotkb:PMS1 protein homolog 2(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS2(gene name synonym)|uniprotkb:PMS2(gene name)|psi-mi:PMS2(display_short)|uniprotkb:PMSL2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267119|imex:IM-27543-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	ensembl:ENSG00000122512(gene)|ensembl:ENST00000265849(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006298"(mismatch repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0032138"(single base insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|mint:P54278|rcsb pdb:1H7S|rcsb pdb:1H7U|rcsb pdb:5U5R|rcsb pdb:6MFQ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|rcsb pdb:1EA6|refseq:NP_000526.2|refseq:NP_001308932.1|refseq:NP_001308933.1|refseq:NP_001308934.1|refseq:NP_001308935.1|refseq:NP_001308936.1|refseq:NP_001308937.1|refseq:NP_001308938.1|refseq:NP_001308939.1|refseq:NP_001308940.1|refseq:NP_001308941.1|refseq:NP_001308942.1|refseq:NP_001308943.1|refseq:NP_001308944.1|refseq:XP_016885888.1|dip:DIP-46295N	-	-	-	figure legend:Fig. 2, Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/12/04	2019/12/04	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:ZEPZOzJgtNSaYyRonkvr/+/30AE9606	rigid:V+h9QsGaEB7a1kNJz2tPPj4Yzzw	false	glutathione s tranferase tag:?-?	sufficient binding region:612-647|necessary binding region:612-625|35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P40692	uniprotkb:P54277	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-2893308|ensembl:ENSP00000406490|uniprotkb:D3DPI1|uniprotkb:Q4VAL4|uniprotkb:Q5FBZ8|uniprotkb:Q5FBZ3|uniprotkb:Q5FBZ6	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:pms1_human(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:PMSL1(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267210|imex:IM-27543-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	refseq:NP_000525.1|ensembl:ENSG00000064933(gene)|ensembl:ENST00000441310(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR036910|interpro:IPR038973|mint:P54277|rcsb pdb:2CS1|refseq:NP_001276337.1|refseq:XP_016859833.1|refseq:XP_016859837.1|refseq:NP_001121616.1|refseq:NP_001121615.1|refseq:NP_001307974.1|refseq:NP_001307975.1|refseq:NP_001307976.1|refseq:NP_001307977.1	-	-	-	figure legend:Fig. 8|comment:Both hPMS1 and hMLH3 compete with hPMS2 for the binding to hMLH1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/12/04	2019/12/04	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:URnCj+2/Inh5Wsc1UFHYh1gowFQ9606	rigid:a/YSUN+B0TNqSs1NsZff2CbJzV8	false	glutathione s tranferase tag:?-?	his tag:?-?|v5 tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P40692	uniprotkb:P54278	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-1162561|uniprotkb:Q5FBW9|uniprotkb:Q5FBX1|uniprotkb:Q5FBX2|uniprotkb:Q52LH6|uniprotkb:Q75MR2|uniprotkb:B2R610|ensembl:ENSP00000265849	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:pms2_human(display_long)|uniprotkb:PMS1 protein homolog 2(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS2(gene name synonym)|uniprotkb:PMS2(gene name)|psi-mi:PMS2(display_short)|uniprotkb:PMSL2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267210|imex:IM-27543-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	ensembl:ENSG00000122512(gene)|ensembl:ENST00000265849(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006298"(mismatch repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0032138"(single base insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|mint:P54278|rcsb pdb:1H7S|rcsb pdb:1H7U|rcsb pdb:5U5R|rcsb pdb:6MFQ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|rcsb pdb:1EA6|refseq:NP_000526.2|refseq:NP_001308932.1|refseq:NP_001308933.1|refseq:NP_001308934.1|refseq:NP_001308935.1|refseq:NP_001308936.1|refseq:NP_001308937.1|refseq:NP_001308938.1|refseq:NP_001308939.1|refseq:NP_001308940.1|refseq:NP_001308941.1|refseq:NP_001308942.1|refseq:NP_001308943.1|refseq:NP_001308944.1|refseq:XP_016885888.1|dip:DIP-46295N	-	-	-	figure legend:Fig. 8|comment:Both hPMS1 and hMLH3 compete with hPMS2 for the binding to hMLH1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/12/04	2019/12/04	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:ZEPZOzJgtNSaYyRonkvr/+/30AE9606	rigid:a/YSUN+B0TNqSs1NsZff2CbJzV8	false	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P40692	uniprotkb:Q9UHC1	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-3893094|uniprotkb:P49751|uniprotkb:Q56DK9|uniprotkb:Q9P292|uniprotkb:Q9UHC0|ensembl:ENSP00000348020	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:mlh3_human(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267228|imex:IM-27543-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	refseq:XP_016876708.1|refseq:XP_006720179.1|refseq:NP_001035197.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005712"(chiasma)|go:"GO:0006298"(mismatch repair)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007144"(female meiosis I)|go:"GO:0008104"(protein localization)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|reactome:R-HSA-912446|ensembl:ENSG00000119684(gene)|ensembl:ENST00000355774(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)	-	-	-	figure legend:Fig. 8|comment:Both hPMS1 and hMLH3 compete with hPMS2 for the binding to hMLH1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/12/04	2019/12/04	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:8FpSX4YxQWxM9HBykG4bJME7HzQ9606	rigid:41D2iPRZ/n8tsEYT1ZO/VcioN4Q	false	glutathione s tranferase tag:?-?	his tag:?-?|v5 tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P40692	uniprotkb:P54278	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-1162561|uniprotkb:Q5FBW9|uniprotkb:Q5FBX1|uniprotkb:Q5FBX2|uniprotkb:Q52LH6|uniprotkb:Q75MR2|uniprotkb:B2R610|ensembl:ENSP00000265849	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:pms2_human(display_long)|uniprotkb:PMS1 protein homolog 2(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS2(gene name synonym)|uniprotkb:PMS2(gene name)|psi-mi:PMS2(display_short)|uniprotkb:PMSL2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kondo et al. (2001)	pubmed:11292842|imex:IM-27543	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22267228|imex:IM-27543-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	ensembl:ENSG00000122512(gene)|ensembl:ENST00000265849(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006298"(mismatch repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0032138"(single base insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|mint:P54278|rcsb pdb:1H7S|rcsb pdb:1H7U|rcsb pdb:5U5R|rcsb pdb:6MFQ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|rcsb pdb:1EA6|refseq:NP_000526.2|refseq:NP_001308932.1|refseq:NP_001308933.1|refseq:NP_001308934.1|refseq:NP_001308935.1|refseq:NP_001308936.1|refseq:NP_001308937.1|refseq:NP_001308938.1|refseq:NP_001308939.1|refseq:NP_001308940.1|refseq:NP_001308941.1|refseq:NP_001308942.1|refseq:NP_001308943.1|refseq:NP_001308944.1|refseq:XP_016885888.1|dip:DIP-46295N	-	-	-	figure legend:Fig. 8|comment:Both hPMS1 and hMLH3 compete with hPMS2 for the binding to hMLH1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/12/04	2019/12/04	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:ZEPZOzJgtNSaYyRonkvr/+/30AE9606	rigid:41D2iPRZ/n8tsEYT1ZO/VcioN4Q	false	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)