#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16836	uniprotkb:Q16836	intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4	intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4	psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym)	psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Barycki et al. (1999)	pubmed:10231530|imex:IM-27363	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21453749|wwpdb:2HDH|wwpdb:3HAD|imex:IM-27363-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3	interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3	-	-	-	figure legend:Fig 1, Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/06/13	2019/06/17	rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606	rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606	rigid:E21LOCvBOzSc6DqP/td7CFBHCks	false	his tag:c-c	his tag:c-c	2	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)