#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Z0S9 uniprotkb:Q9WUU9 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-8458361|uniprotkb:Q7TS87|intact:MINT-4101590|ensembl:ENSMUSP00000125960 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:ganp_mouse(display_long)|uniprotkb:GC-associated DNA primase(gene name synonym)|uniprotkb:Mcm3ap(gene name)|psi-mi:Mcm3ap(display_short)|uniprotkb:Ganp(gene name synonym)|uniprotkb:Map80(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974677|imex:IM-26645-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_062307.2|ensembl:ENSMUST00000170795(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|ensembl:ENSMUSG00000001150(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0015031"(protein transport)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0034728"(nucleosome organization)|go:"GO:0042393"(histone binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0070390"(transcription export complex 2)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR031907|interpro:IPR031908|interpro:IPR031910|interpro:IPR034265|interpro:IPR035979|mint:Q9WUU9|go:"GO:0005737"(cytoplasm)|refseq:NM_019434.3 (identity) - - comment:mint|function:May be involved in the nuclear localization pathway of MCM3 figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:luT5z03YUaij2qdyKC5yHLJ6ZSs10090 rigid:Z3sxoItVPekLthp6sxd3l8eS9gk false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q8K3H0 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-400377|uniprotkb:Q3UJP7|uniprotkb:Q69ZJ9|uniprotkb:Q8BWZ8|uniprotkb:Q8VCJ8|uniprotkb:Q9CUW4|ensembl:ENSMUSP00000042875 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:dp13a_mouse(display_long)|uniprotkb:Appl1(gene name)|psi-mi:Appl1(display_short)|uniprotkb:Dip13a(gene name synonym)|uniprotkb:Kiaa1428(gene name synonym)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974701|imex:IM-26645-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_660256.1|ensembl:ENSMUSG00000040760(gene)|ensembl:ENSMUST00000036570(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR037929|mint:Q8K3H0|reactome:R-MMU-418889|refseq:MF113398.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:1ZML/W0Qi+jMAeZQ7PXfiHA6YBE10090 rigid:dYt4EG9DozEHyY9dXjsigbuwXg0 false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O70343 uniprotkb:Q9Z0S9 intact:EBI-1371053|uniprotkb:L0AM20|uniprotkb:L0AN96|uniprotkb:L0APB0|uniprotkb:Q3UP72|ensembl:ENSMUSP00000117040 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 psi-mi:prgc1_mouse(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym) psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974689|imex:IM-26645-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032930.1|dip:DIP-38447N|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014823"(response to activity)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|ensembl:ENSMUST00000132734(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0031325"(positive regulation of cellular metabolic process)|ensembl:ENSMUSG00000029167(gene)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|rcsb pdb:3F7D|refseq:NM_008904.2 (identity) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rigid:ZcvXAFB8J/nY8Jre3mjFKF8D35w false nub:n-n cub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q04750 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-6666222|ensembl:ENSMUSP00000105094|uniprotkb:A2A4B7 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:top1_mouse(display_long)|uniprotkb:Top1(gene name)|psi-mi:Top1(display_short)|uniprotkb:Top-1(gene name synonym)|uniprotkb:DNA topoisomerase I(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974713|imex:IM-26645-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000070544(gene)|ensembl:ENSMUST00000109468(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0003682"(chromatin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|reactome:R-MMU-4615885|mint:Q04750|refseq:NP_033434.2|refseq:NM_009408.2(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:nY84yAtfGCI/k+B2u3mM151r+zU10090 rigid:z2qY4FMLvDl+O8hVpHBNS9ROoBY false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q8CCS2 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20974810|ensembl:ENSMUSP00000106596|uniprotkb:Q149R3 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:f155a_mouse(display_long)|uniprotkb:Fam155a(gene name)|psi-mi:Fam155a(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974826|imex:IM-26645-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0098703"(calcium ion import across plasma membrane)|interpro:IPR029604|rcsb pdb:7CU3|ensembl:ENSMUST00000110969(transcript)|ensembl:ENSMUSG00000079157(gene)|refseq:NP_001334056.1|refseq:NP_775622.1|refseq:AC160456.8(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:IqQU8xd8e/sKc+wWi+YElWulVfA10090 rigid:cZa/SYz5+Yruku2ucXYIQASYq/A false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q9JIB0 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-309406|uniprotkb:Q9CWZ0|ensembl:ENSMUSP00000038485 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:mog1_mouse(display_long)|uniprotkb:Rangrf(gene name)|psi-mi:Rangrf(display_short)|uniprotkb:Rangnrf(gene name synonym)|uniprotkb:Mog1(gene name synonym)|uniprotkb:Ran-binding protein MOG1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974786|imex:IM-26645-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_067304.1|refseq:NP_001272370.1|refseq:NP_001272372.1|ensembl:ENSMUSG00000032892(gene)|ensembl:ENSMUST00000038644(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090226"(regulation of microtubule nucleation by Ran protein signal transduction)|go:"GO:0098905"(regulation of bundle of His cell action potential)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR007681(Ran-interacting Mog1 protein)|interpro:IPR016123(Mog1/PsbP, alpha/beta/alpha sandwich)|reactome:R-MMU-5576892|refseq:NM_021329.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:XokpBjXOQhfSlb4curkFG1EW6QU10090 rigid:oCMFvDD0k/XvuevrRCF00WRO0lA false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:P00848 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20974749|ensembl:ENSMUSP00000080996 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:atp6_mouse(display_long)|uniprotkb:F-ATPase protein 6(gene name synonym)|uniprotkb:Mtatp6(gene name)|psi-mi:Mtatp6(display_short)|uniprotkb:Atp6(gene name synonym)|uniprotkb:Atpase6(gene name synonym)|uniprotkb:mt-Atp6(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974774|imex:IM-26645-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000064357(gene)|ensembl:ENSMUST00000082408(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0007568"(aging)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR000568(ATPase, F0 complex, subunit A)|interpro:IPR023011|interpro:IPR035908|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_904333.1|refseq:AF093677.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:I0GrZQSSPpmdcToXNzANeLG2Yxc10090 rigid:NpFsuLEvBGQ8MeCCPAKTTgUKeZQ false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 intact:EBI-16882370 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 - psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:calm1_calm2_calm3_mouse(display_short)|psi-mi:EBI-16882370(display_long)|intact:CALM(author assigned name) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974737|imex:IM-26645-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:1304"(molecule set) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) uniprotkb:P0DP26(set member)|uniprotkb:P0DP27(set member)|uniprotkb:P0DP28(set member)|refseq:NM_007590.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 - - false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q8BJF9 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-8586771|ensembl:ENSMUSP00000004965|uniprotkb:Q9CT65|intact:UNK-5506442|uniprotkb:Q80UZ4 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:chm2b_mouse(display_long)|uniprotkb:Chromatin-modifying protein 2b(gene name synonym)|uniprotkb:Chmp2b(gene name)|psi-mi:Chmp2b(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974725|imex:IM-26645-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) reactome:R-MMU-1632852|reactome:R-MMU-5620971|reactome:R-MMU-917729|reactome:R-MMU-9668328|ensembl:ENSMUSG00000004843(gene)|ensembl:ENSMUST00000004965(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0050890"(cognition)|go:"GO:0061952"(midbody abscission)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR005024(Snf7)|refseq:NP_081155.1|refseq:NM_026879.3(identity) - - function:"Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo"|comment:mint figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:2GwXwnlmN5GXP5mwePyufUiYrww10090 rigid:M+yO3fivqfUjs0tFCyi62/XBHl8 false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q68EF0 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-16730154|ensembl:ENSMUSP00000020375 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:rab3i_mouse(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:Rab3ip(gene name)|psi-mi:Rab3ip(display_short)|uniprotkb:Rabin8(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974798|imex:IM-26645-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000064181(gene)|ensembl:ENSMUST00000020375(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990635"(proximal dendrite)|interpro:IPR040351|mint:Q68EF0|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-5620922|reactome:R-MMU-8876198|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|refseq:NP_001003950.1|refseq:NM_001359645.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:vJqpNpn2gSYd/89uDKCBOO/KQDs10090 rigid:rCWD4Drw3O7oFD8ddxhIKOSOMYo false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q6XUX1 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-17170963|ensembl:ENSMUSP00000035358|uniprotkb:Q3ULK4|uniprotkb:Q5EBN5|uniprotkb:Q8C7D4|uniprotkb:Q8C923|uniprotkb:Q9CTP7 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:dusty_mouse(display_long)|uniprotkb:Dusty protein kinase(gene name synonym)|uniprotkb:Receptor-interacting serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:Dstyk(gene name)|psi-mi:Dstyk(display_short)|uniprotkb:Ripk5(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974850|imex:IM-26645-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000042046(gene)|ensembl:ENSMUST00000045110(transcript)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0005524"(ATP binding)|refseq:NP_766104.2|refseq:NM_172516.4(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:0Qq+16GF206jlZu+1LvUfpX2wro10090 rigid:VLMgSUpml4qGEZFLhlOEUrMKjYo false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:O89113 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20974862|ensembl:ENSMUSP00000056948|uniprotkb:Q8CGI0 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:ier5_mouse(display_long)|uniprotkb:Ier5(gene name)|psi-mi:Ier5(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974880|imex:IM-26645-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000056708(gene)|ensembl:ENSMUST00000055322(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response)|refseq:NP_034630.1|refseq:NM_010500.2(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:eVNmRlFhkIb7XbdfiFzIYVfHgOA10090 rigid:pZ3s+k610Vg0hf/oI9tx2U/55NI false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:P60060 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20974892|ensembl:ENSMUSP00000105269|ensembl:ENSMUSP00000105270|ensembl:ENSMUSP00000105271|ensembl:ENSMUSP00000137362|uniprotkb:P38384 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:sc61g_mouse(display_long)|uniprotkb:Sec61g(gene name)|psi-mi:Sec61g(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974920|imex:IM-26645-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000078974(gene)|ensembl:ENSMUST00000109641(transcript)|ensembl:ENSMUST00000109642(transcript)|ensembl:ENSMUST00000109643(transcript)|ensembl:ENSMUST00000178855(transcript)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|reactome:R-MMU-9609523|refseq:NP_001103441.1|refseq:NP_001103442.1|refseq:NP_035473.2|refseq:XP_006496454.1|refseq:XP_006514454.1|refseq:NM_011343.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:zWwGsMkSqZ4mZP7YH1E9WI2QETs10090 rigid:W49KfvfSiN3g0QdZuvGG1a961Uw false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:O35678 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-8321042|uniprotkb:Q9D9G8|uniprotkb:Q3V2R0|intact:MINT-1856023|ensembl:ENSMUSP00000086872|ensembl:ENSMUSP00000109215 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:mgll_mouse(display_long)|uniprotkb:Mgll(gene name)|psi-mi:Mgll(display_short)|uniprotkb:Monoacylglycerol lipase(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974932|imex:IM-26645-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_035974.1|refseq:NP_001159721.1|refseq:NP_001159722.1|refseq:NP_001159723.1|ensembl:ENSMUSG00000033174(gene)|ensembl:ENSMUST00000089449(transcript)|ensembl:ENSMUST00000113585(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043196"(varicosity)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046464"(acylglycerol catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0052651"(monoacylglycerol catabolic process)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR022742|interpro:IPR029058|mint:O35678|reactome:R-MMU-1482883|reactome:R-MMU-426048|go:"GO:0045202"(synapse)|refseq:XM_011241332.1(identity) - - comment:mint|function:"Hydrolyzes 2-arachidonoylglycerol, a putative endocannabinoid (By similarity). Converts monoacylglycerides to free fatty acids and glycerol" figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:lAA6+66UELy1hzM67dCsNMzRfJQ10090 rigid:X0TZxMode0XPRxt7MEZdeqmAJ5E false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:O35657 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-16826908|ensembl:ENSMUSP00000007253|uniprotkb:O55220|uniprotkb:Q99KG9 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:neur1_mouse(display_long)|uniprotkb:Neu1(gene name)|psi-mi:Neu1(display_short)|uniprotkb:Neu(gene name synonym)|uniprotkb:G9 sialidase(gene name synonym)|uniprotkb:Lysosomal sialidase(gene name synonym)|uniprotkb:N-acetyl-alpha-neuraminidase 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974944|imex:IM-26645-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000007038(gene)|ensembl:ENSMUST00000007253(transcript)|go:"GO:0004308"(exo-alpha-sialidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006689"(ganglioside catabolic process)|go:"GO:0009313"(oligosaccharide catabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016997"(alpha-sialidase activity)|go:"GO:0030054"(cell junction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0052794"("exo-alpha-(2->3)-sialidase activity")|go:"GO:0052795"("exo-alpha-(2->6)-sialidase activity")|go:"GO:0052796"("exo-alpha-(2->8)-sialidase activity")|go:"GO:2000291"(regulation of myoblast proliferation)|interpro:IPR011040(Neuraminidase)|interpro:IPR026856|interpro:IPR036278|reactome:R-MMU-1660662|reactome:R-MMU-4085001|reactome:R-MMU-6798695|refseq:NP_035023.3|refseq:U93702.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:LjcKs289dTSQBKTfShveeza1CdA10090 rigid:UPkjdz8IDDD0NfISmVWNgROGrtw false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q9JHS3 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-1038198|ensembl:ENSMUSP00000029698 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:ltor2_mouse(display_long)|uniprotkb:Lamtor2(gene name)|psi-mi:Lamtor2(display_short)|uniprotkb:Late endosomal/lysosomal Mp1-interacting protein(gene name synonym)|uniprotkb:Endosomal adaptor protein p14(gene name synonym)|uniprotkb:Mapbpip(gene name synonym)|uniprotkb:Roadblock domain-containing protein 3(gene name synonym)|uniprotkb:Robld3(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2(gene name synonym)|uniprotkb:Mitogen-activated protein-binding protein-interacting protein(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974838|imex:IM-26645-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_112538.1|ensembl:ENSMUSG00000028062(gene)|ensembl:ENSMUST00000029698(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0010761"(fibroblast migration)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0150116"(regulation of cell-substrate junction organization)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR037587|mint:Q9JHS3|rcsb pdb:1SKO|rcsb pdb:1SZV|rcsb pdb:1VET|rcsb pdb:1VEU|rcsb pdb:2ZL1|rcsb pdb:3CPT|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-5674135|reactome:R-MMU-6798695|reactome:R-MMU-8943724|reactome:R-MMU-9639288|refseq:NM_031248.4(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:KrmdNGhK/FO3ifZrNSEQnV+DPys10090 rigid:Ov/7yHfDivtbIScpYmgwInjviZE false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q9QZ23 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-8353745|uniprotkb:Q6VNZ7|uniprotkb:Q8CF80|uniprotkb:Q3ULE0|intact:MINT-1853650|uniprotkb:Q9D1B7|intact:UNK-5414301|ensembl:ENSMUSP00000113332 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:nfu1_mouse(display_long)|uniprotkb:Nfu1(gene name)|psi-mi:Nfu1(display_short)|uniprotkb:Hirip5(gene name synonym)|uniprotkb:HIRA-interacting protein 5(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975087|imex:IM-26645-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_064429.2|refseq:NP_001164062.1|refseq:XP_006506482.1|refseq:XP_006506483.1|ensembl:ENSMUSG00000029993(gene)|ensembl:ENSMUST00000117583(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001075(NIF system FeS cluster assembly, NifU, C-terminal)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR034904|interpro:IPR036498|rcsb pdb:1VEH|mint:Q9QZ23|refseq:NM_020045.3(identity) - - comment:mint figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:tcHBsLvZluYI+gHdnsedlbiEuTw10090 rigid:U5y3TmP+lWVnlmVxiIJUnTYfAwk false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q8CE22 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20974956|ensembl:ENSMUSP00000071815|uniprotkb:P70413|uniprotkb:Q3TUR9|uniprotkb:Q80VR8|uniprotkb:Q8BQX6|uniprotkb:Q8CA56|uniprotkb:Q8CCZ0 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:dmtf1_mouse(display_long)|uniprotkb:Cyclin-D-interacting Myb-like protein 1(gene name synonym)|uniprotkb:Dmtf1(gene name)|psi-mi:Dmtf1(display_short)|uniprotkb:Dmp1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20974994|imex:IM-26645-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000042508(gene)|ensembl:ENSMUST00000071921(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|refseq:NP_001103797.1|refseq:NP_035936.3|refseq:XP_011238970.1|refseq:NR_152859.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:MHzF0BuEoRUvKXNOqnv86CvNwhw10090 rigid:0sjOeAsgq7RsAQ5Cbg4iwtWQAYA false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q8K1S2 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975006|ensembl:ENSMUSP00000128521|uniprotkb:B9EHC0 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:unc5d_mouse(display_long)|uniprotkb:Protein unc-5 homolog 4(gene name synonym)|uniprotkb:Protein unc-5 homolog D(gene name synonym)|uniprotkb:Unc5d(gene name)|psi-mi:Unc5d(display_short)|uniprotkb:Unc5h4(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975038|imex:IM-26645-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000063626(gene)|ensembl:ENSMUST00000168630(transcript)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021859"(pyramidal neuron differentiation)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042058|refseq:NP_694775.1|refseq:NM_001347498.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:QBfvznOKgPGmwzsK7682/BP9eF010090 rigid:BDXHtfhjmmqEBh3kuy1lDCpB0UQ false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q80TM9 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-6908752|ensembl:ENSMUSP00000022469|uniprotkb:Q2YDV7|uniprotkb:Q8C354|uniprotkb:Q8C4X9|uniprotkb:Q8CBH0|uniprotkb:Q91XW6|uniprotkb:Q99LG6|uniprotkb:Q9EPW8|uniprotkb:Q9WUM6 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:nisch_mouse(display_long)|uniprotkb:Nisch(gene name)|psi-mi:Nisch(display_short)|uniprotkb:Kiaa0975(gene name synonym)|uniprotkb:Imidazoline receptor 1(gene name synonym)|uniprotkb:Imidazoline receptor I-1-like protein(gene name synonym)|uniprotkb:Imidazoline-1 receptor(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975050|imex:IM-26645-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000021910(gene)|ensembl:ENSMUST00000022469(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048243"(norepinephrine secretion)|go:"GO:0055037"(recycling endosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001683(Phox-like)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036871|interpro:IPR037904|mint:Q80TM9|reactome:R-MMU-9013149|reactome:R-MMU-9696264|reactome:R-MMU-9696270|refseq:NP_073147.2|refseq:NM_022656.2(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:4WK1HdDSTowpkrUNW9iMr+WB4t010090 rigid:YabqL2PTB1Gi09nAPwGtOH+xwLA false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q8K3A4 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975062|uniprotkb:Q3U0N5|uniprotkb:Q3UK55|uniprotkb:Q99JS2 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:rhno1_mouse(display_long)|uniprotkb:Rhno1(gene name)|psi-mi:Rhno1(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975075|imex:IM-26645-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) reactome:R-MMU-5685938|reactome:R-MMU-5693607|reactome:R-MMU-5693616|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0007049"(cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR029293|reactome:R-MMU-6804756|reactome:R-MMU-69473|refseq:NM_001326585.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:VGe+qBOn9iFofXoQB8h90yP12E010090 rigid:kbUPi0ZMvBqbrDhjDaiwHwWEmxQ false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q99JX4 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-8312665|ensembl:ENSMUSP00000028592|intact:MINT-1869888|uniprotkb:Q5EBI5|uniprotkb:Q3TI04 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:eif3m_mouse(display_long)|uniprotkb:Pcid1(gene name synonym)|uniprotkb:Eif3m(gene name)|psi-mi:Eif3m(display_short)|uniprotkb:PCI domain-containing protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975099|imex:IM-26645-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) reactome:R-MMU-72706|reactome:R-MMU-72702|ensembl:ENSMUSG00000027170(gene)|ensembl:ENSMUST00000028592(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027528|interpro:IPR036390|interpro:IPR040750|mint:Q99JX4|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|refseq:NP_663355.1|dip:DIP-59784N|refseq:NM_145380.2(identity) - - function:Component of the eIF-3 complex, which binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:b2PpL8mxfJDS47A/ZSr163bG4dg10090 rigid:FyLhbEI85CVwwxma1Ly0ftp6TKk false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q9DB07 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975111|ensembl:ENSMUSP00000002099|ensembl:ENSMUSP00000113845|ensembl:ENSMUSP00000159011|uniprotkb:Q91Z06|uniprotkb:Q9JHT1 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:ift46_mouse(display_long)|uniprotkb:Ift46(gene name)|psi-mi:Ift46(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975142|imex:IM-26645-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000002031(gene)|ensembl:ENSMUST00000002099(transcript)|ensembl:ENSMUST00000118186(transcript)|ensembl:ENSMUST00000239014(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0015031"(protein transport)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0031514"(motile cilium)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035082"(axoneme assembly)|go:"GO:0042073"(intraciliary transport)|go:"GO:0044782"(cilium organization)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0097546"(ciliary base)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR022088|reactome:R-MMU-5620924|refseq:NP_076320.2|refseq:XP_006510734.1|refseq:NM_023831.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:wb9qO+0K6yT8IP58PGoGwOYkBZU10090 rigid:Ch7mXCV1piG/i8LwMdeTtqRtLYI false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q9D8M3 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975154|ensembl:ENSMUSP00000112644|uniprotkb:Q3UU69|uniprotkb:Q9DCK0 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:hrg1_mouse(display_long)|uniprotkb:Heme-responsive gene 1 protein homolog(gene name synonym)|uniprotkb:Solute carrier family 48 member 1(gene name synonym)|uniprotkb:Slc48a1(gene name)|psi-mi:Slc48a1(display_short)|uniprotkb:Hrg1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975173|imex:IM-26645-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000081534(gene)|ensembl:ENSMUST00000117892(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|interpro:IPR026218|refseq:NP_080629.1|refseq:NM_026353.4(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:9rzR3Kzz/tN7j4dCPa/L5I925TQ10090 rigid:GUCjl7V0c7cn+kUNxv/404gGU/Y false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:P39654 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975185|ensembl:ENSMUSP00000019068|uniprotkb:Q4FJY9|uniprotkb:Q5F2E3|uniprotkb:Q6PHB2 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:lox15_mouse(display_long)|uniprotkb:12/15-lipoxygenase(gene name synonym)|uniprotkb:Arachidonate 12-lipoxygenase, leukocyte-type(gene name synonym)|uniprotkb:Arachidonate omega-6 lipoxygenase(gene name synonym)|uniprotkb:Arachidonate 15-lipoxygenase(gene name synonym)|uniprotkb:Hepoxilin A3 synthase Alox15(gene name synonym)|uniprotkb:Linoleate 13S-lipoxygenase(gene name synonym)|uniprotkb:Alox15(gene name)|psi-mi:Alox15(display_short)|uniprotkb:Alox12l(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975245|imex:IM-26645-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000018924(gene)|ensembl:ENSMUST00000019068(transcript)|go:"GO:0001503"(ossification)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0004052"("arachidonate 12(S)-lipoxygenase activity")|go:"GO:0005506"(iron ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016165"(linoleate 13S-lipoxygenase activity)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030282"(bone mineralization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034440"(lipid oxidation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035963"(cellular response to interleukin-13)|go:"GO:0042060"(wound healing)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0047977"(hepoxilin-epoxide hydrolase activity)|go:"GO:0050473"(arachidonate 15-lipoxygenase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051120"(hepoxilin A3 synthase activity)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901074"(regulation of engulfment of apoptotic cell)|go:"GO:2001303"(lipoxin A4 biosynthetic process)|interpro:IPR000907(Lipoxygenase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|reactome:R-MMU-2142691|reactome:R-MMU-2142712|reactome:R-MMU-2142770|reactome:R-MMU-9018677|reactome:R-MMU-9018681|reactome:R-MMU-9018896|reactome:R-MMU-9023661|reactome:R-MMU-9025106|reactome:R-MMU-9026286|refseq:NP_033790.3|refseq:EU007907.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:MGqQExEYrYEMHlarv1Q2so9q6wg10090 rigid:j/ICpYdu+eAzBhj3baQclX7JIOI false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q91VC9 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975269|ensembl:ENSMUSP00000046212|ensembl:ENSMUSP00000129712|uniprotkb:Q3TGB7|uniprotkb:Q3UA74|uniprotkb:Q8N9T5 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:ghitm_mouse(display_long)|uniprotkb:Mitochondrial morphology and cristae structure 1(gene name synonym)|uniprotkb:Ghitm(gene name)|psi-mi:Ghitm(display_short)|uniprotkb:Mics1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975291|imex:IM-26645-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000041028(gene)|ensembl:ENSMUST00000042564(transcript)|ensembl:ENSMUST00000165649(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR006214(Protein of unknown function UPF0005)|interpro:IPR035871|refseq:NP_510963.1|refseq:XP_006519435.1|refseq:NP_001186051.1|refseq:NM_001359902.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:x8UDTctBcoo3uzYdtB/nKrhh6s810090 rigid:uuJA5lftTn7SDcSi4Z3l+lP1VaM false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q8R2U7 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975303|ensembl:ENSMUSP00000030360|uniprotkb:Q3TE62|uniprotkb:Q9CTP9 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:lrc42_mouse(display_long)|uniprotkb:Lrrc42(gene name)|psi-mi:Lrrc42(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975316|imex:IM-26645-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000028617(gene)|ensembl:ENSMUST00000030360(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR039631|refseq:NP_084261.1|refseq:NM_029985.2(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:Igi1aUPq8kdWPGfGBDlJ86mRscY10090 rigid:ueFU9N4c5hOsVnJFiEz0WMrV0U4 false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:O35621 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975328|ensembl:ENSMUSP00000023112 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:pmm1_mouse(display_long)|uniprotkb:Pmm1(gene name)|psi-mi:Pmm1(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975351|imex:IM-26645-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000022474(gene)|ensembl:ENSMUST00000023112(transcript)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR005002(Eukaryotic phosphomannomutase)|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR023214|interpro:IPR036412|mint:O35621|reactome:R-MMU-446205|interpro:IPR043169|refseq:NP_038900.1|refseq:NM_001282040.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:a8YXtBGRJLhB/BVRD3SX+8QRUgw10090 rigid:/FtEpGNIgKHQjHXV+3tjav8AVPQ false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:O35739 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-12591632 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:klf9_mouse(display_long)|uniprotkb:Klf9(gene name)|psi-mi:Klf9(display_short)|uniprotkb:Bteb(gene name synonym)|uniprotkb:Bteb-1(gene name synonym)|uniprotkb:Bteb1(gene name synonym)|uniprotkb:Basic transcription element-binding protein 1(gene name synonym)|uniprotkb:GC-box-binding protein 1(gene name synonym)|uniprotkb:Transcription factor BTEB1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975363|imex:IM-26645-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007566"(embryo implantation)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0071387"(cellular response to cortisol stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NM_010638.4 (identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:Djegi76L43gige+6CTDtxQ/aTa410090 rigid:tqaCQgQgI/93hPVK5sbY6I4Rc+U false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:P61924 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-8458149|intact:MINT-1864573|uniprotkb:Q9Y3C3|ensembl:ENSMUSP00000097738 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:copz1_mouse(display_long)|uniprotkb:Copz1(gene name)|psi-mi:Copz1(display_short)|uniprotkb:Copz(gene name synonym)|uniprotkb:Zeta-1-coat protein(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975375|imex:IM-26645-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_062791.1|ensembl:ENSMUSG00000060992(gene)|ensembl:ENSMUST00000100162(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:1901998"(toxin transport)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|mint:P61924|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-MMU-6807878|reactome:R-MMU-6811434|refseq:NM_019817.2(identity) - - comment:mint|function:"The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors"|function:The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/23 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:1/IgMqSz7ThLUzNhR4ARUq+Gr6I10090 rigid:1Roiad98qpZdTcljV0J7aTgCM8c false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q60817 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-494674|uniprotkb:Q3THR6|uniprotkb:Q4FZL8|ensembl:ENSMUSP00000073532 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:naca_mouse(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:Alpha-NAC/1.9.2(gene name synonym)|uniprotkb:Naca(gene name)|psi-mi:Naca(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975387|imex:IM-26645-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_001269905.1|refseq:NP_038636.2|ensembl:ENSMUSG00000061315(gene)|ensembl:ENSMUST00000073868(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042060"(wound healing)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051451"(myoblast migration)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:1901227"(negative regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|refseq:NM_013608.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:baQnjY8mAho/qN+/clg+YBjE8zw10090 rigid:Avfb0QMje+47eHKa2sJwO18iMaQ false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q7TMY8 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-646786|uniprotkb:A2AFQ1|uniprotkb:Q4G2Z1|uniprotkb:Q5BMM7|uniprotkb:Q6NS61|uniprotkb:Q8BNJ7|uniprotkb:Q8CFH2|uniprotkb:Q8VD14|uniprotkb:Q921M5|uniprotkb:Q9R0P2|ensembl:ENSMUSP00000108241 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:huwe1_mouse(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:E3Histone(gene name synonym)|uniprotkb:Huwe1(gene name)|psi-mi:Huwe1(display_short)|uniprotkb:Kiaa0312(gene name synonym)|uniprotkb:Ureb1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975257|imex:IM-26645-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_067498.4|ensembl:ENSMUSG00000025261(gene)|ensembl:ENSMUST00000112622(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061025"(membrane fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7TMY8|reactome:R-MMU-6798695|reactome:R-MMU-983168|refseq:AY772010.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:bfiYTxkedQUu7pdjryOi5z+tYP410090 rigid:MsG1EnSXC6+qO1uQLbF2hC2D1+M false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:P12710 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-4282834|ensembl:ENSMUSP00000064655 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:fabpl_mouse(display_long)|uniprotkb:Fabp1(gene name)|psi-mi:Fabp1(display_short)|uniprotkb:Fabpl(gene name synonym)|uniprotkb:14 kDa selenium-binding protein(gene name synonym)|uniprotkb:Fatty acid-binding protein 1(gene name synonym)|uniprotkb:Liver-type fatty acid-binding protein(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975399|imex:IM-26645-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016209"(antioxidant activity)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032052"(bile acid binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036094"(small molecule binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051345"(positive regulation of hydrolase activity)|ensembl:ENSMUSG00000054422(gene)|ensembl:ENSMUST00000067492(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|refseq:NP_059095.1|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR012674(Calycin)|interpro:IPR031259|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR031276|mint:P12710|reactome:R-MMU-163560|reactome:R-MMU-189483|reactome:R-MMU-400206|reactome:R-MMU-9707564|refseq:NM_017399.5(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:cB3Av7VZvtWsvsnH2gTjx5Kwc/U10090 rigid:I0arNaSaFmNerSwzbO0mSgHaG48 false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:P60487 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975411|ensembl:ENSMUSP00000086796 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:plpp_mouse(display_long)|uniprotkb:Pdxp(gene name)|psi-mi:Pdxp(display_short)|uniprotkb:Cin(gene name synonym)|uniprotkb:Plp(gene name synonym)|uniprotkb:Plpp(gene name synonym)|uniprotkb:Pyridoxal 5'-phosphate phosphatase(gene name synonym)|uniprotkb:Pyridoxal phosphate phosphatase(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975455|imex:IM-26645-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000116165(gene)|ensembl:ENSMUST00000089378(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006114"(glycerol biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019838"(growth factor binding)|go:"GO:0030496"(midbody)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031247"(actin rod assembly)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032361"(pyridoxal phosphate catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033883"(pyridoxal phosphatase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043136"(glycerol-3-phosphatase activity)|go:"GO:0070938"(contractile ring)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR006349(2-phosphoglycolate phosphatase, eukaryotic)|interpro:IPR006357(HAD-superfamily hydrolase, subfamily IIA)|interpro:IPR023214|interpro:IPR036412|rcsb pdb:4BKM|rcsb pdb:4BX0|rcsb pdb:4BX2|rcsb pdb:4BX3|rcsb pdb:5AES|refseq:NP_064667.2|refseq:NM_020271.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:BcbfjKeoC4MEWR35ggHwUEDsl1810090 rigid:Zs9uRiJFy+VZbwUVhiwdV2xjaIw false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q6PIE5 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975467|imex:IM-26645-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N|refseq:NM_178405.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090 rigid:PxD6y/jqxac4g0eOteuK4rJkJsk false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q9CZU6 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-773122|uniprotkb:Q3UDP3|ensembl:ENSMUSP00000005826 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:cisy_mouse(display_long)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym)|uniprotkb:Cs(gene name)|psi-mi:Cs(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975628|imex:IM-26645-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_080720.1|ensembl:ENSMUSG00000005683(gene)|ensembl:ENSMUST00000005826(transcript)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0046912"(acyltransferase, acyl groups converted into alkyl on transfer)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|mint:Q9CZU6|rcsb pdb:3NZI|reactome:R-MMU-71403|refseq:NM_026444.4(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:0Ct6UHozD3vl5QxB0YOeKsSEUQw10090 rigid:W6igTrXcIuHeQ1FOTbpbuKUhSUw false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q8BXK8 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975584|ensembl:ENSMUSP00000027521|uniprotkb:Q3UHA0|uniprotkb:Q6ZPX9|uniprotkb:Q8BZG0 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:agap1_mouse(display_long)|uniprotkb:Centaurin-gamma-2(gene name synonym)|uniprotkb:Agap1(gene name)|psi-mi:Agap1(display_short)|uniprotkb:Centg2(gene name synonym)|uniprotkb:Kiaa1099(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975616|imex:IM-26645-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000055013(gene)|ensembl:ENSMUST00000027521(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|refseq:NP_001032213.1|refseq:NP_835220.1|refseq:NM_178119.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:O3E2sxo8cbxygZiWvNWKxUkhkmg10090 rigid:AAdv11Hr8MjPHNev5VOAE/v4V1U false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q9JLJ5 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975535|ensembl:ENSMUSP00000006557|ensembl:ENSMUSP00000064816|ensembl:ENSMUSP00000126685|uniprotkb:Q9D1B2 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:elov1_mouse(display_long)|uniprotkb:3-keto acyl-CoA synthase Elovl1(gene name synonym)|uniprotkb:ELOVL fatty acid elongase 1(gene name synonym)|uniprotkb:Very long chain 3-ketoacyl-CoA synthase 1(gene name synonym)|uniprotkb:Very long chain 3-oxoacyl-CoA synthase 1(gene name synonym)|uniprotkb:Elovl1(gene name)|psi-mi:Elovl1(display_short)|uniprotkb:Ssc1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975572|imex:IM-26645-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000006390(gene)|ensembl:ENSMUST00000006557(transcript)|ensembl:ENSMUST00000067896(transcript)|ensembl:ENSMUST00000167636(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0009922"(fatty acid elongase activity)|go:"GO:0019367"(fatty acid elongation, saturated fatty acid)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034625"(fatty acid elongation, monounsaturated fatty acid)|go:"GO:0034626"(fatty acid elongation, polyunsaturated fatty acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0102336"(3-oxo-arachidoyl-CoA synthase activity)|go:"GO:0102337"(3-oxo-cerotoyl-CoA synthase activity)|go:"GO:0102338"(3-oxo-lignoceronyl-CoA synthase activity)|go:"GO:0102756"(very-long-chain 3-ketoacyl-CoA synthase activity)|interpro:IPR002076(GNS1/SUR4 membrane protein)|interpro:IPR030457|interpro:IPR033681|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|refseq:NP_001034264.1|refseq:NP_001034265.1|refseq:NP_062295.1|refseq:XP_006503296.1|refseq:NM_019422.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:J7brMSLe35A6/LGN/lfWzICT7UI10090 rigid:TaI+TnY4fza7iqFFrHovxEv9zG8 false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:P97401 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975479|ensembl:ENSMUSP00000028389|uniprotkb:O09075|uniprotkb:O09093|uniprotkb:Q91W58 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:sfrp3_mouse(display_long)|uniprotkb:Frezzled(gene name synonym)|uniprotkb:Fritz(gene name synonym)|uniprotkb:Frizzled-related protein 1(gene name synonym)|uniprotkb:FrzB-1(gene name synonym)|uniprotkb:Frzb(gene name)|psi-mi:Frzb(display_short)|uniprotkb:Fiz(gene name synonym)|uniprotkb:Fre(gene name synonym)|uniprotkb:Frzb1(gene name synonym)|uniprotkb:Sfrp3(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975523|imex:IM-26645-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000027004(gene)|ensembl:ENSMUST00000028389(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010721"(negative regulation of cell development)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0070367"(negative regulation of hepatocyte differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR015526(Frizzled related)|interpro:IPR018933|interpro:IPR020067|interpro:IPR026556|interpro:IPR035813|interpro:IPR036790|interpro:IPR041759|rcsb pdb:1IJX|refseq:NP_035486.1|refseq:NM_011356.4(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:qD8HKutWHh1dc1w2SO0I0D49Gxs10090 rigid:QpsqyTzbIBRH2d853NtcbAz7yUY false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:Q3UV70 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-20975652|ensembl:ENSMUSP00000050521|ensembl:ENSMUSP00000103932 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:pdp1_mouse(display_long)|uniprotkb:Protein phosphatase 2C(gene name synonym)|uniprotkb:Pyruvate dehydrogenase phosphatase catalytic subunit 1(gene name synonym)|uniprotkb:Pdp1(gene name)|psi-mi:Pdp1(display_short)|uniprotkb:Ppm2c(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975682|imex:IM-26645-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) ensembl:ENSMUSG00000049225(gene)|ensembl:ENSMUST00000056050(transcript)|ensembl:ENSMUST00000108297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004741"("[pyruvate dehydrogenase (lipoamide)] phosphatase activity")|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1904184"(positive regulation of pyruvate dehydrogenase activity)|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|reactome:R-MMU-204174|refseq:NP_001028625.1|refseq:NP_001091700.1|refseq:NP_001091701.1|refseq:NP_001277316.1|refseq:NP_001277320.1|refseq:NM_001098231.1(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:scci13XiiO2gO++kxqbm9HBcJbY10090 rigid:kdsoLeALK73C5EU8gRk5yycgdv0 false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:O89051 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-777528|uniprotkb:Q545S7|ensembl:ENSMUSP00000022704 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:itm2b_mouse(display_long)|uniprotkb:Protein E25B(gene name synonym)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975640|imex:IM-26645-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1|refseq:NM_010261.2(identity) refseq:NP_032436.1|ensembl:ENSMUSG00000022108(gene)|ensembl:ENSMUST00000022704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|refseq:NM_008410.3(identity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/11/06 2018/11/30 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:JJmwqKAmZ6AGiFHXltZdO80MUnI10090 rigid:n82+LpgDUqpuypzSB7bDJuqpjOY false cub:n-n nub:n-n - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0S9 uniprotkb:P61924 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-8458149|intact:MINT-1864573|uniprotkb:Q9Y3C3|ensembl:ENSMUSP00000097738 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:copz1_mouse(display_long)|uniprotkb:Copz1(gene name)|psi-mi:Copz1(display_short)|uniprotkb:Copz(gene name synonym)|uniprotkb:Zeta-1-coat protein(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975750|imex:IM-26645-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1 refseq:NP_062791.1|ensembl:ENSMUSG00000060992(gene)|ensembl:ENSMUST00000100162(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:1901998"(toxin transport)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|mint:P61924|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-MMU-6807878|reactome:R-MMU-6811434 - - comment:mint|function:"The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors"|function:The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2018/11/06 2018/11/22 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:1/IgMqSz7ThLUzNhR4ARUq+Gr6I10090 rigid:1Roiad98qpZdTcljV0J7aTgCM8c false n-venus:c-c|flag tag:n-n c-venus:c-c|ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0S9 uniprotkb:Q9JHS3 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 intact:EBI-1038198|ensembl:ENSMUSP00000029698 psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:ltor2_mouse(display_long)|uniprotkb:Lamtor2(gene name)|psi-mi:Lamtor2(display_short)|uniprotkb:Late endosomal/lysosomal Mp1-interacting protein(gene name synonym)|uniprotkb:Endosomal adaptor protein p14(gene name synonym)|uniprotkb:Mapbpip(gene name synonym)|uniprotkb:Roadblock domain-containing protein 3(gene name synonym)|uniprotkb:Robld3(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2(gene name synonym)|uniprotkb:Mitogen-activated protein-binding protein-interacting protein(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975764|imex:IM-26645-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1 refseq:NP_112538.1|ensembl:ENSMUSG00000028062(gene)|ensembl:ENSMUST00000029698(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0010761"(fibroblast migration)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0150116"(regulation of cell-substrate junction organization)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR037587|mint:Q9JHS3|rcsb pdb:1SKO|rcsb pdb:1SZV|rcsb pdb:1VET|rcsb pdb:1VEU|rcsb pdb:2ZL1|rcsb pdb:3CPT|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-5674135|reactome:R-MMU-6798695|reactome:R-MMU-8943724|reactome:R-MMU-9639288 - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2018/11/06 2018/11/22 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 rogid:KrmdNGhK/FO3ifZrNSEQnV+DPys10090 rigid:Ov/7yHfDivtbIScpYmgwInjviZE false n-venus:c-c|flag tag:n-n c-venus:c-c|ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0S9 intact:EBI-16882370 intact:EBI-476965|ensembl:ENSMUSP00000076227|uniprotkb:Q3TDB4 - psi-mi:praf1_mouse(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:Prenylin(gene name synonym)|uniprotkb:Rabac1(gene name)|psi-mi:Rabac1(display_short)|uniprotkb:Pra(gene name synonym)|uniprotkb:Pra1(gene name synonym)|uniprotkb:Praf1(gene name synonym) psi-mi:calm1_calm2_calm3_mouse(display_short)|psi-mi:EBI-16882370(display_long)|intact:CALM(author assigned name) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Abu et al. (2019) pubmed:30925931|imex:IM-26645 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20975774|imex:IM-26645-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:1304"(molecule set) ensembl:ENSMUSG00000003380(gene)|ensembl:ENSMUST00000076961(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_034391.1 uniprotkb:P0DP26(set member)|uniprotkb:P0DP27(set member)|uniprotkb:P0DP28(set member) - - - figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2018/11/06 2018/11/23 rogid:cBDA6mrObxTPZRfwXIJSP3YkNIc10090 - - false n-venus:c-c|flag tag:n-n c-venus:c-c|ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)