#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P30086	uniprotkb:Q9NS68	intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800339|imex:IM-26547-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f3a|comment:"Moreover, in the lysates of the cultured U87 cells, the endogenous interactions of TROY with RKIP, prohibitin, or RhoGDIα were detected. The data suggest that TROY interacts with RKIP, prohibitin and RhoGDIα in glioma cells (Fig. 3a–f)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:FZyt9iO7am5KUd9qR4ufe8nYqes	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P30086	uniprotkb:Q9NS68	intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800344|imex:IM-26547-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:FZyt9iO7am5KUd9qR4ufe8nYqes	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35232	uniprotkb:Q9NS68	intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800349|imex:IM-26547-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:UgL+6G24BGXJW/8gOESEZFfLRMo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35232	uniprotkb:Q9NS68	intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800354|imex:IM-26547-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f3d F4a|comment:the FBS treatment did not affect the association of TROY with prohibitin or RhoGDIα.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:UgL+6G24BGXJW/8gOESEZFfLRMo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P52565	uniprotkb:Q9NS68	intact:EBI-712693|intact:EBI-718039|ensembl:ENSP00000269321|ensembl:ENSP00000441348|ensembl:ENSP00000464205|intact:EBI-2840752|uniprotkb:A8MXW0|uniprotkb:B4DDD3|uniprotkb:B4DUV9|uniprotkb:B2R5X1|uniprotkb:Q6IBM5	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:gdir1_human(display_long)|uniprotkb:Rho-GDI alpha(gene name synonym)|uniprotkb:ARHGDIA(gene name)|psi-mi:ARHGDIA(display_short)|uniprotkb:GDIA1(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800359|imex:IM-26547-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141522(gene)|ensembl:ENST00000269321(transcript)|ensembl:ENST00000541078(transcript)|ensembl:ENST00000580685(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071461"(cellular response to redox state)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52565|rcsb pdb:1CC0|rcsb pdb:1FSO|rcsb pdb:1FST|rcsb pdb:1FT0|rcsb pdb:1FT3|rcsb pdb:1HH4|rcsb pdb:1KMT|rcsb pdb:1QVY|rcsb pdb:1RHO|rcsb pdb:2BXW|rcsb pdb:2JHS|rcsb pdb:2JHT|rcsb pdb:2JHU|rcsb pdb:2JHV|rcsb pdb:2JHW|rcsb pdb:2JHX|rcsb pdb:2JHY|rcsb pdb:2JHZ|rcsb pdb:2JI0|rcsb pdb:2N80|reactome:R-HSA-193634|reactome:R-HSA-209563|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013407|reactome:R-HSA-9013408|go:"GO:0005634"(nucleus)|refseq:NP_001172006.1|refseq:NP_001172007.1|refseq:NP_004300.1|refseq:NP_001288169.1|refseq:NP_001288170.1|refseq:NP_001288171.1|refseq:NP_001288172.1	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f3e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:nHmwosTUeo1R72Mp5uHLYdcBofk9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:bs6JpDTj2RvFNg1MtcSweqCnzRc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P52565	uniprotkb:Q9NS68	intact:EBI-712693|intact:EBI-718039|ensembl:ENSP00000269321|ensembl:ENSP00000441348|ensembl:ENSP00000464205|intact:EBI-2840752|uniprotkb:A8MXW0|uniprotkb:B4DDD3|uniprotkb:B4DUV9|uniprotkb:B2R5X1|uniprotkb:Q6IBM5	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:gdir1_human(display_long)|uniprotkb:Rho-GDI alpha(gene name synonym)|uniprotkb:ARHGDIA(gene name)|psi-mi:ARHGDIA(display_short)|uniprotkb:GDIA1(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800364|imex:IM-26547-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141522(gene)|ensembl:ENST00000269321(transcript)|ensembl:ENST00000541078(transcript)|ensembl:ENST00000580685(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071461"(cellular response to redox state)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52565|rcsb pdb:1CC0|rcsb pdb:1FSO|rcsb pdb:1FST|rcsb pdb:1FT0|rcsb pdb:1FT3|rcsb pdb:1HH4|rcsb pdb:1KMT|rcsb pdb:1QVY|rcsb pdb:1RHO|rcsb pdb:2BXW|rcsb pdb:2JHS|rcsb pdb:2JHT|rcsb pdb:2JHU|rcsb pdb:2JHV|rcsb pdb:2JHW|rcsb pdb:2JHX|rcsb pdb:2JHY|rcsb pdb:2JHZ|rcsb pdb:2JI0|rcsb pdb:2N80|reactome:R-HSA-193634|reactome:R-HSA-209563|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013407|reactome:R-HSA-9013408|go:"GO:0005634"(nucleus)|refseq:NP_001172006.1|refseq:NP_001172007.1|refseq:NP_004300.1|refseq:NP_001288169.1|refseq:NP_001288170.1|refseq:NP_001288171.1|refseq:NP_001288172.1	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f3f f4a|comment:the FBS treatment did not affect the association of TROY with prohibitin or RhoGDIα.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:nHmwosTUeo1R72Mp5uHLYdcBofk9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:bs6JpDTj2RvFNg1MtcSweqCnzRc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P30086	uniprotkb:Q9NS68	intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800391|imex:IM-26547-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f4a|comment:we examined the interaction of TROY with RKIP, prohibitin, and RhoGDIα in glioma cells after FBS exposure. As shown in Fig. 4a–d, the interaction of TROY with RKIP was significantly enhanced after FBS exposure in the glioma cells.|agonist:FBS|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:FZyt9iO7am5KUd9qR4ufe8nYqes	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35232	uniprotkb:Q9NS68	intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800376|imex:IM-26547-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f3g|comment:"We also examined if TROY and its binding-partners were co-localized in the glioma cells. TROY and the binding partners were observed to be co-expressed in the glioma cells through immunocytochemical staining (Fig. 3g)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:UgL+6G24BGXJW/8gOESEZFfLRMo	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P30086	uniprotkb:Q9NS68	intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800381|imex:IM-26547-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f3g|comment:"We also examined if TROY and its binding-partners were co-localized in the glioma cells. TROY and the binding partners were observed to be co-expressed in the glioma cells through immunocytochemical staining (Fig. 3g)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:FZyt9iO7am5KUd9qR4ufe8nYqes	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P52565	uniprotkb:Q9NS68	intact:EBI-712693|intact:EBI-718039|ensembl:ENSP00000269321|ensembl:ENSP00000441348|ensembl:ENSP00000464205|intact:EBI-2840752|uniprotkb:A8MXW0|uniprotkb:B4DDD3|uniprotkb:B4DUV9|uniprotkb:B2R5X1|uniprotkb:Q6IBM5	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:gdir1_human(display_long)|uniprotkb:Rho-GDI alpha(gene name synonym)|uniprotkb:ARHGDIA(gene name)|psi-mi:ARHGDIA(display_short)|uniprotkb:GDIA1(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800386|imex:IM-26547-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141522(gene)|ensembl:ENST00000269321(transcript)|ensembl:ENST00000541078(transcript)|ensembl:ENST00000580685(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071461"(cellular response to redox state)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52565|rcsb pdb:1CC0|rcsb pdb:1FSO|rcsb pdb:1FST|rcsb pdb:1FT0|rcsb pdb:1FT3|rcsb pdb:1HH4|rcsb pdb:1KMT|rcsb pdb:1QVY|rcsb pdb:1RHO|rcsb pdb:2BXW|rcsb pdb:2JHS|rcsb pdb:2JHT|rcsb pdb:2JHU|rcsb pdb:2JHV|rcsb pdb:2JHW|rcsb pdb:2JHX|rcsb pdb:2JHY|rcsb pdb:2JHZ|rcsb pdb:2JI0|rcsb pdb:2N80|reactome:R-HSA-193634|reactome:R-HSA-209563|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013407|reactome:R-HSA-9013408|go:"GO:0005634"(nucleus)|refseq:NP_001172006.1|refseq:NP_001172007.1|refseq:NP_004300.1|refseq:NP_001288169.1|refseq:NP_001288170.1|refseq:NP_001288171.1|refseq:NP_001288172.1	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:f3g|comment:"We also examined if TROY and its binding-partners were co-localized in the glioma cells. TROY and the binding partners were observed to be co-expressed in the glioma cells through immunocytochemical staining (Fig. 3g)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line)	-	2018/10/25	2018/10/25	rogid:nHmwosTUeo1R72Mp5uHLYdcBofk9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:bs6JpDTj2RvFNg1MtcSweqCnzRc	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q9JLL3	uniprotkb:P30086	intact:EBI-20800437|ensembl:ENSMUSP00000106865|ensembl:ENSMUSP00000106867|uniprotkb:Q80T13|uniprotkb:Q812G3|uniprotkb:Q9JHF1|uniprotkb:Q9JJH6|uniprotkb:Q9JLL2|uniprotkb:Q9QXW7	intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313	psi-mi:tnr19_mouse(display_long)|uniprotkb:Tnfrsf19(gene name)|psi-mi:Tnfrsf19(display_short)|uniprotkb:Taj(gene name synonym)|uniprotkb:Troy(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:Toxicity and JNK inducer(gene name synonym)	psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800435|imex:IM-26547-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUST00000111234(transcript)|ensembl:ENSMUST00000111236(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9JLL3|ensembl:ENSMUSG00000060548(gene)|refseq:NP_001157627.1|refseq:NP_038897.4	refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N	-	-	-	figure legend:f5a f5c|comment:"We further examined whether TROY (234–371 aa) could disrupt the interaction between TROY and RKIP. We prepared TROY (234–371 aa) protein tagged with TAT peptide. The GST-TROY-ICD and His-RKIP fusion proteins were incubated with the TAT protein (10 μM). Then, the GST pull-down assay was performed. RKIP bound to TROY was remarkably decreased when the TAT protein was applied (Fig. 5c, d), suggesting that the TAT-TROY (234–371 aa) protein can disrupt the interaction of TROY/RKIP in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/25	2018/10/25	rogid:+IJNpFX3QemkckKIS7frZysZupk10090	rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606	rigid:DyWxgtYbP2k/5fRVYy7SXcLe74w	false	binding-associated region:194-416|glutathione s tranferase tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9JLL3	uniprotkb:Q9JLL3	intact:EBI-20800437|ensembl:ENSMUSP00000106865|ensembl:ENSMUSP00000106867|uniprotkb:Q80T13|uniprotkb:Q812G3|uniprotkb:Q9JHF1|uniprotkb:Q9JJH6|uniprotkb:Q9JLL2|uniprotkb:Q9QXW7	intact:EBI-20800437|ensembl:ENSMUSP00000106865|ensembl:ENSMUSP00000106867|uniprotkb:Q80T13|uniprotkb:Q812G3|uniprotkb:Q9JHF1|uniprotkb:Q9JJH6|uniprotkb:Q9JLL2|uniprotkb:Q9QXW7	psi-mi:tnr19_mouse(display_long)|uniprotkb:Tnfrsf19(gene name)|psi-mi:Tnfrsf19(display_short)|uniprotkb:Taj(gene name synonym)|uniprotkb:Troy(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:Toxicity and JNK inducer(gene name synonym)	psi-mi:tnr19_mouse(display_long)|uniprotkb:Tnfrsf19(gene name)|psi-mi:Tnfrsf19(display_short)|uniprotkb:Taj(gene name synonym)|uniprotkb:Troy(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:Toxicity and JNK inducer(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-20800435|imex:IM-26547-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUST00000111234(transcript)|ensembl:ENSMUST00000111236(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9JLL3|ensembl:ENSMUSG00000060548(gene)|refseq:NP_001157627.1|refseq:NP_038897.4	ensembl:ENSMUST00000111234(transcript)|ensembl:ENSMUST00000111236(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9JLL3|ensembl:ENSMUSG00000060548(gene)|refseq:NP_001157627.1|refseq:NP_038897.4	-	-	-	figure legend:f5a f5c|comment:"We further examined whether TROY (234–371 aa) could disrupt the interaction between TROY and RKIP. We prepared TROY (234–371 aa) protein tagged with TAT peptide. The GST-TROY-ICD and His-RKIP fusion proteins were incubated with the TAT protein (10 μM). Then, the GST pull-down assay was performed. RKIP bound to TROY was remarkably decreased when the TAT protein was applied (Fig. 5c, d), suggesting that the TAT-TROY (234–371 aa) protein can disrupt the interaction of TROY/RKIP in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/25	2018/10/25	rogid:+IJNpFX3QemkckKIS7frZysZupk10090	rogid:+IJNpFX3QemkckKIS7frZysZupk10090	rigid:DyWxgtYbP2k/5fRVYy7SXcLe74w	false	binding-associated region:194-416|glutathione s tranferase tag:?-?	transactivating tag:?-?|binding-associated region:234-371	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P30086	uniprotkb:Q9JLL3	intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313	intact:EBI-20800437|ensembl:ENSMUSP00000106865|ensembl:ENSMUSP00000106867|uniprotkb:Q80T13|uniprotkb:Q812G3|uniprotkb:Q9JHF1|uniprotkb:Q9JJH6|uniprotkb:Q9JLL2|uniprotkb:Q9QXW7	psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym)	psi-mi:tnr19_mouse(display_long)|uniprotkb:Tnfrsf19(gene name)|psi-mi:Tnfrsf19(display_short)|uniprotkb:Taj(gene name synonym)|uniprotkb:Troy(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:Toxicity and JNK inducer(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20813096|imex:IM-26547-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N	ensembl:ENSMUST00000111234(transcript)|ensembl:ENSMUST00000111236(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9JLL3|ensembl:ENSMUSG00000060548(gene)|refseq:NP_001157627.1|refseq:NP_038897.4	-	-	-	figure legend:sf4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/10/25	2018/10/30	rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606	rogid:+IJNpFX3QemkckKIS7frZysZupk10090	rigid:DyWxgtYbP2k/5fRVYy7SXcLe74w	false	green fluorescent protein tag:n-n	ha tag:?-?|binding-associated region:234-371	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P30086	uniprotkb:Q9JLL3	intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313	intact:EBI-20800437|ensembl:ENSMUSP00000106865|ensembl:ENSMUSP00000106867|uniprotkb:Q80T13|uniprotkb:Q812G3|uniprotkb:Q9JHF1|uniprotkb:Q9JJH6|uniprotkb:Q9JLL2|uniprotkb:Q9QXW7	psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym)	psi-mi:tnr19_mouse(display_long)|uniprotkb:Tnfrsf19(gene name)|psi-mi:Tnfrsf19(display_short)|uniprotkb:Taj(gene name synonym)|uniprotkb:Troy(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:Toxicity and JNK inducer(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20813112|imex:IM-26547-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N	ensembl:ENSMUST00000111234(transcript)|ensembl:ENSMUST00000111236(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9JLL3|ensembl:ENSMUSG00000060548(gene)|refseq:NP_001157627.1|refseq:NP_038897.4	-	-	-	figure legend:sf4b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/10/25	2018/10/30	rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606	rogid:+IJNpFX3QemkckKIS7frZysZupk10090	rigid:DyWxgtYbP2k/5fRVYy7SXcLe74w	false	green fluorescent protein tag:n-n	ha tag:?-?|binding-associated region:234-371	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35232	uniprotkb:Q9JLL3	intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113	intact:EBI-20800437|ensembl:ENSMUSP00000106865|ensembl:ENSMUSP00000106867|uniprotkb:Q80T13|uniprotkb:Q812G3|uniprotkb:Q9JHF1|uniprotkb:Q9JJH6|uniprotkb:Q9JLL2|uniprotkb:Q9QXW7	psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym)	psi-mi:tnr19_mouse(display_long)|uniprotkb:Tnfrsf19(gene name)|psi-mi:Tnfrsf19(display_short)|uniprotkb:Taj(gene name synonym)|uniprotkb:Troy(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:Toxicity and JNK inducer(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20813122|imex:IM-26547-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948	ensembl:ENSMUST00000111234(transcript)|ensembl:ENSMUST00000111236(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9JLL3|ensembl:ENSMUSG00000060548(gene)|refseq:NP_001157627.1|refseq:NP_038897.4	-	-	-	figure legend:sf4d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/10/25	2018/10/30	rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606	rogid:+IJNpFX3QemkckKIS7frZysZupk10090	rigid:csM7iHFVS8GmACbY/1M35OnnoZw	false	green fluorescent protein tag:n-n	ha tag:?-?|binding-associated region:234-371	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35232	uniprotkb:Q9JLL3	intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113	intact:EBI-20800437|ensembl:ENSMUSP00000106865|ensembl:ENSMUSP00000106867|uniprotkb:Q80T13|uniprotkb:Q812G3|uniprotkb:Q9JHF1|uniprotkb:Q9JJH6|uniprotkb:Q9JLL2|uniprotkb:Q9QXW7	psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym)	psi-mi:tnr19_mouse(display_long)|uniprotkb:Tnfrsf19(gene name)|psi-mi:Tnfrsf19(display_short)|uniprotkb:Taj(gene name synonym)|uniprotkb:Troy(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:Toxicity and JNK inducer(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20813132|imex:IM-26547-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948	ensembl:ENSMUST00000111234(transcript)|ensembl:ENSMUST00000111236(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9JLL3|ensembl:ENSMUSG00000060548(gene)|refseq:NP_001157627.1|refseq:NP_038897.4	-	-	-	figure legend:sf4c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/10/25	2018/10/30	rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606	rogid:+IJNpFX3QemkckKIS7frZysZupk10090	rigid:csM7iHFVS8GmACbY/1M35OnnoZw	false	green fluorescent protein tag:n-n	ha tag:?-?|binding-associated region:234-371	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P30086	uniprotkb:Q9JLL3	intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313	intact:EBI-20800437|ensembl:ENSMUSP00000106865|ensembl:ENSMUSP00000106867|uniprotkb:Q80T13|uniprotkb:Q812G3|uniprotkb:Q9JHF1|uniprotkb:Q9JJH6|uniprotkb:Q9JLL2|uniprotkb:Q9QXW7	psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym)	psi-mi:tnr19_mouse(display_long)|uniprotkb:Tnfrsf19(gene name)|psi-mi:Tnfrsf19(display_short)|uniprotkb:Taj(gene name synonym)|uniprotkb:Troy(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:Toxicity and JNK inducer(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20813151|imex:IM-26547-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N	ensembl:ENSMUST00000111234(transcript)|ensembl:ENSMUST00000111236(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9JLL3|ensembl:ENSMUSG00000060548(gene)|refseq:NP_001157627.1|refseq:NP_038897.4	-	-	-	figure legend:sf4e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/10/25	2018/10/30	rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606	rogid:+IJNpFX3QemkckKIS7frZysZupk10090	rigid:DyWxgtYbP2k/5fRVYy7SXcLe74w	false	green fluorescent protein tag:n-n	glutathione s tranferase tag:?-?|binding-associated region:234-371	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35232	uniprotkb:Q9JLL3	intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113	intact:EBI-20800437|ensembl:ENSMUSP00000106865|ensembl:ENSMUSP00000106867|uniprotkb:Q80T13|uniprotkb:Q812G3|uniprotkb:Q9JHF1|uniprotkb:Q9JJH6|uniprotkb:Q9JLL2|uniprotkb:Q9QXW7	psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym)	psi-mi:tnr19_mouse(display_long)|uniprotkb:Tnfrsf19(gene name)|psi-mi:Tnfrsf19(display_short)|uniprotkb:Taj(gene name synonym)|uniprotkb:Troy(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:Toxicity and JNK inducer(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liu et al. (2018)	pubmed:30337686|imex:IM-26547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20813161|imex:IM-26547-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948	ensembl:ENSMUST00000111234(transcript)|ensembl:ENSMUST00000111236(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9JLL3|ensembl:ENSMUSG00000060548(gene)|refseq:NP_001157627.1|refseq:NP_038897.4	-	-	-	figure legend:sf4f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/10/25	2018/10/30	rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606	rogid:+IJNpFX3QemkckKIS7frZysZupk10090	rigid:csM7iHFVS8GmACbY/1M35OnnoZw	false	green fluorescent protein tag:n-n	glutathione s tranferase tag:?-?|binding-associated region:234-371	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)