#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P53549	uniprotkb:P40327	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13901|uniprotkb:D6VRY1|ensemblfungi:YDL007W	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:prs4_yeast(display_long)|uniprotkb:RPT2(gene name)|psi-mi:RPT2(display_short)|uniprotkb:YHS4(gene name synonym)|uniprotkb:YTA5(gene name synonym)|uniprotkb:YDL007W(locus name)|uniprotkb:D2920(orf name)|uniprotkb:Tat-binding homolog 5(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	refseq:NP_010277.1|sgd:S000002165|ensemblfungi:YDL007W(gene)|ensemblfungi:YDL007W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0034629"|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:4CR2|rcsb pdb:3JCP|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-532668|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P40327|dip:DIP-6282N	-	crc64:0EA42A599E2B2E2A	crc64:EB735354C3A0EBD4	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:nSy31Q+snoZMZrFmXscv8/HQYk0559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P33297	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N	-	crc64:0EA42A599E2B2E2A	crc64:C215422033FCE830	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P33298	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13905|ensemblfungi:YDR394W|uniprotkb:D6VT28	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:prs6b_yeast(display_long)|uniprotkb:RPT3(gene name)|psi-mi:RPT3(display_short)|uniprotkb:YNT1(gene name synonym)|uniprotkb:YTA2(gene name synonym)|uniprotkb:YDR394W(locus name)|uniprotkb:D9509.14(orf name)|uniprotkb:Protein YNT1(gene name synonym)|uniprotkb:Tat-binding homolog 2(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	sgd:S000002802|ensemblfungi:YDR394W(gene)|ensemblfungi:YDR394W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:NP_010682.3|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|rcsb pdb:2DZN|rcsb pdb:2DZO|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33298|dip:DIP-1587N|interpro:IPR003960(AAA ATPase, conserved site)	-	crc64:0EA42A599E2B2E2A	crc64:E12F0995A60732BD	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:teaQwAlS0ruTNKbLkX7kP4lkn7o559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P33299	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N	-	crc64:0EA42A599E2B2E2A	crc64:8454BBC9D549EC5C	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:Q01939	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N	-	crc64:0EA42A599E2B2E2A	crc64:9C59E92A0794F60F	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P21243	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13975|uniprotkb:P15708|ensemblfungi:YGL011C|uniprotkb:D6VUC6	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psa1_yeast(display_long)|uniprotkb:SCL1(gene name)|psi-mi:SCL1(display_short)|uniprotkb:PRC2(gene name synonym)|uniprotkb:PRS2(gene name synonym)|uniprotkb:YGL011C(locus name)|uniprotkb:Proteasome component C7-alpha(gene name synonym)|uniprotkb:Macropain subunit C7-alpha(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex C7(gene name synonym)|uniprotkb:Proteasome component Y8(gene name synonym)|uniprotkb:SCL1 suppressor protein(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	sgd:S000002979|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|ensemblfungi:YGL011C(gene)|ensemblfungi:YGL011C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y69|rcsb pdb:4Y8K|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y8L|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|refseq:NP_011504.3|mint:P21243|dip:DIP-2810N	-	crc64:0EA42A599E2B2E2A	crc64:5B938C862BC8D7EB	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:CIMZa9bvEUzZ4k7XGnaC4irMOpo559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P23639	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13959|ensemblfungi:YML092C|uniprotkb:D6W0J3	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psa2_yeast(display_long)|uniprotkb:PRE8(gene name)|psi-mi:PRE8(display_short)|uniprotkb:PRS4(gene name synonym)|uniprotkb:YML092C(locus name)|uniprotkb:Proteasome component Y7(gene name synonym)|uniprotkb:Macropain subunit Y7(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y7(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:2ZCY|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3OEV|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4INU|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5CZ5|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5JHR|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QV4|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:5MPC|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6EF3|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWF|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HVY|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-983168|reactome:R-SCE-8948751|ensemblfungi:YML092C(gene)|ensemblfungi:YML092C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|refseq:NP_013618.1|sgd:S000004557|mint:P23639|dip:DIP-2822N	-	crc64:0EA42A599E2B2E2A	crc64:12D7DFB1AA10E9FE	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:HiJr+UwwGu+wQImwgq3TiHYELx8559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P23638	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13967|ensemblfungi:YGR135W|uniprotkb:D6VUR7	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psa3_yeast(display_long)|uniprotkb:PRE9(gene name)|psi-mi:PRE9(display_short)|uniprotkb:YGR135W(locus name)|uniprotkb:PRS5(gene name synonym)|uniprotkb:Proteasome component Y13(gene name synonym)|uniprotkb:Macropain subunit Y13(gene name synonym)|uniprotkb:Proteinase YSCE subunit 13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y13(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	sgd:S000003367|ensemblfungi:YGR135W(gene)|ensemblfungi:YGR135W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0080129"(proteasome core complex assembly)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:3OKJ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NO1|rcsb pdb:4NNN|rcsb pdb:4NO6|rcsb pdb:4NNW|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|rcsb pdb:6J2Q|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QVL|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|reactome:R-SCE-983168|reactome:R-SCE-8948751|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4QZ2|rcsb pdb:4Y70|rcsb pdb:4Y8H|rcsb pdb:4Y74|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y75|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y8R|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:4YA3|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:3OEV|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5FGF|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L60|rcsb pdb:5L5Z|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|refseq:NP_011651.3|mint:P23638|dip:DIP-2823N	-	crc64:0EA42A599E2B2E2A	crc64:B43BB05233A01A9E	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:5F6HrO7MputR68OA/1SAdFfJa4g559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P40303	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13980|ensemblfungi:YOL038W|uniprotkb:D6W229	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psa4_yeast(display_long)|uniprotkb:PRE6(gene name)|psi-mi:PRE6(display_short)|uniprotkb:YOL038W(locus name)|uniprotkb:Proteasome component PRE6(gene name synonym)|uniprotkb:Macropain subunit PRE6(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE6(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE6(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	ensemblfungi:YOL038W(gene)|ensemblfungi:YOL038W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4QZ0|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4Y8G|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXL|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FG7|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5L6C|rcsb pdb:6FVW|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6FVX|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6HWD|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4HNP|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QV0|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|refseq:NP_014604.1|sgd:S000005398|mint:P40303|dip:DIP-4844N	-	crc64:0EA42A599E2B2E2A	crc64:73AEE63B836E618A	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:G8IQr0G8FhiWc0DYUlh3vecHQsU559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P32379	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13971|ensemblfungi:YGR253C|uniprotkb:D6VV33	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psa5_yeast(display_long)|uniprotkb:PUP2(gene name)|psi-mi:PUP2(display_short)|uniprotkb:DOA5(gene name synonym)|uniprotkb:YGR253C(locus name)|uniprotkb:G9155(orf name)|uniprotkb:Proteasome component PUP2(gene name synonym)|uniprotkb:Macropain subunit PUP2(gene name synonym)|uniprotkb:Proteinase YSCE subunit PUP2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PUP2(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y69|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|refseq:NP_011769.1|sgd:S000003485|ensemblfungi:YGR253C(gene)|ensemblfungi:YGR253C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2Z5C|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:3UN4|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QVN|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QLV|rcsb pdb:4QVY|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|mint:P32379|dip:DIP-1193N	-	crc64:0EA42A599E2B2E2A	crc64:E8EDEB212BF4EC6E	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:d9WDpDu+8VHYVXV0dRDCcL6UaSk559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P40302	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	crc64:0EA42A599E2B2E2A	crc64:C43CBCC1C6B9E39E	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P21242	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13963|ensemblfungi:YOR362C|uniprotkb:D6W357	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psa7_yeast(display_long)|uniprotkb:PRE10(gene name)|psi-mi:PRE10(display_short)|uniprotkb:PRC1(gene name synonym)|uniprotkb:PRS1(gene name synonym)|uniprotkb:O6650(orf name)|uniprotkb:YOR362C(locus name)|uniprotkb:Proteasome component C1(gene name synonym)|uniprotkb:Macropain subunit C1(gene name synonym)|uniprotkb:Proteinase YSCE subunit 1(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	ensemblfungi:YOR362C(gene)|ensemblfungi:YOR362C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR037555|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:1FNT|interpro:IPR023332|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QW6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4Y7Y|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5A5B|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5D0X|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L5E|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5L67|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6HTC|rcsb pdb:6FVW|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6FVX|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6HV4|rcsb pdb:6G8M|rcsb pdb:6HV5|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|rcsb pdb:6HW5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-5668541|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:1G0U|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3SDI|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QLS|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|refseq:NP_015007.1|sgd:S000005889|mint:P21242|dip:DIP-1526N	-	crc64:0EA42A599E2B2E2A	crc64:1E51D904CF336747	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:tVLLjztJDttaRM40dHah/J06g0E559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P38624	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-14005|ensemblfungi:YJL001W|uniprotkb:D6VWH4	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psb1_yeast(display_long)|uniprotkb:PRE3(gene name)|psi-mi:PRE3(display_short)|uniprotkb:YJL001W(locus name)|uniprotkb:J1407(orf name)|uniprotkb:Macropain subunit PRE3(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE3(gene name synonym)|uniprotkb:Proteasome component PRE3(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	ensemblfungi:YJL001W(gene)|ensemblfungi:YJL001W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037559|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QV5|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:4Y8Q|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5CZ4|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5CZ5|rcsb pdb:5L52|rcsb pdb:5CZ6|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L54|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5L5Z|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:5NIF|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4QZ5|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|refseq:NP_012533.1|sgd:S000003538|mint:P38624|dip:DIP-1527N	-	crc64:0EA42A599E2B2E2A	crc64:BD1FCE649678D86B	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:CGl4wdsYSRNO3iXRKjgJw/W+qrQ559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P25043	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-14009|ensemblfungi:YOR157C|uniprotkb:D6W2L4	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psb2_yeast(display_long)|uniprotkb:PUP1(gene name)|psi-mi:PUP1(display_short)|uniprotkb:YOR157C(locus name)|uniprotkb:Macropain subunit PUP1(gene name synonym)|uniprotkb:Proteinase YSCE subunit PUP1(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PUP1(gene name synonym)|uniprotkb:Proteasome component PUP1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	sgd:S000005683|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5WVK|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6FVW|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:5MPB|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|rcsb pdb:6HW7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-174113|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QZ2|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y8M|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|ensemblfungi:YOR157C(gene)|ensemblfungi:YOR157C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|refseq:NP_014800.3|mint:P25043|dip:DIP-2818N	-	crc64:0EA42A599E2B2E2A	crc64:13A8F2B75584539A	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:tQLgAHq3RInD/qP9hIqISxdNd7w559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P25451	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13993|ensemblfungi:YER094C|uniprotkb:D3DM02	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psb3_yeast(display_long)|uniprotkb:PUP3(gene name)|psi-mi:PUP3(display_short)|uniprotkb:Proteasome component PUP3(gene name synonym)|uniprotkb:YER094C(locus name)|uniprotkb:Macropain subunit PUP3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PUP3(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4QWK|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|go:"GO:0004175"(endopeptidase activity)|ensemblfungi:YER094C(gene)|ensemblfungi:YER094C_mRNA(transcript)|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y80|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061133"(endopeptidase activator activity)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:2F16|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5BXN|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5FGG|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5MPC|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5NIF|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:3SDI|rcsb pdb:4INR|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4INT|rcsb pdb:4QLT|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2C|sgd:S000000896|refseq:NP_011020.3|mint:P25451|dip:DIP-2039N	-	crc64:0EA42A599E2B2E2A	crc64:5AA92D746454BCB7	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:T49ZHqQs5rEDpaoe/mE2E8pEeSg559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P22141	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13988|ensemblfungi:YER012W|uniprotkb:D3DLQ9	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psb4_yeast(display_long)|uniprotkb:PRE1(gene name)|psi-mi:PRE1(display_short)|uniprotkb:YER012W(locus name)|uniprotkb:Proteasome component C11(gene name synonym)|uniprotkb:Macropain subunit C11(gene name synonym)|uniprotkb:Proteinase YSCE subunit 11(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C11(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|ensemblfungi:YER012W(gene)|ensemblfungi:YER012W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061133"(endopeptidase activator activity)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|refseq:NP_010928.1|sgd:S000000814|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|reactome:R-SCE-983168|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|mint:P22141|dip:DIP-2808N	-	crc64:0EA42A599E2B2E2A	crc64:ED43D319A5895B40	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:tzWxNgSLM/MVJpa7jSoNaS0I12Q559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P30656	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-14001|ensemblfungi:YPR103W|uniprotkb:D6W4A1	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psb5_yeast(display_long)|uniprotkb:PRE2(gene name)|psi-mi:PRE2(display_short)|uniprotkb:DOA3(gene name synonym)|uniprotkb:PRG1(gene name synonym)|uniprotkb:YPR103W(locus name)|uniprotkb:P8283.10(orf name)|uniprotkb:Macropain subunit PRE2(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE2(gene name synonym)|uniprotkb:Proteasome component PRE2(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HUV|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6HWF|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8J|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXN|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5CGF|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5FGE|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L63|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4R00|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QW7|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|go:"GO:0080129"(proteasome core complex assembly)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|ensemblfungi:YPR103W(gene)|ensemblfungi:YPR103W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3DY3|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:4Q1S|rcsb pdb:4NO9|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|refseq:NP_015428.1|sgd:S000006307|mint:P30656|dip:DIP-2806N	-	crc64:0EA42A599E2B2E2A	crc64:D0EBAC611F7A4F37	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:brv4JvZPOIqABrJ9xWTCx+npeLs559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P23724	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13984|ensemblfungi:YBL041W|uniprotkb:D6VPV7	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psb6_yeast(display_long)|uniprotkb:PRE7(gene name)|psi-mi:PRE7(display_short)|uniprotkb:PRS3(gene name synonym)|uniprotkb:PTS1(gene name synonym)|uniprotkb:YBL0407(orf name)|uniprotkb:YBL041W(locus name)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|ensemblfungi:YBL041W(gene)|rcsb pdb:3JCP|ensemblfungi:YBL041W_mRNA(transcript)|rcsb pdb:3MG0|go:"GO:0004175"(endopeptidase activity)|rcsb pdb:3MG4|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:3MG6|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:3MG7|rcsb pdb:3MG8|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:5L68|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HTB|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-69601|refseq:NP_009512.1|sgd:S000000137|mint:P23724|dip:DIP-2821N	-	crc64:0EA42A599E2B2E2A	crc64:770A4DF1DF0A0F0E	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:WzmtcPCO24lWABFyM7pXZaI9wj0559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P30657	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-13997|uniprotkb:E9P8Z8|ensemblfungi:YFR050C|uniprotkb:D6VTT3	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:psb7_yeast(display_long)|uniprotkb:PRE4(gene name)|psi-mi:PRE4(display_short)|uniprotkb:YFR050C(locus name)|uniprotkb:Macropain subunit PRE4(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE4(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE4(gene name synonym)|uniprotkb:Proteasome component PRE4(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5FGD|rcsb pdb:5L5U|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:5L60|rcsb pdb:6G7F|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:6G8M|rcsb pdb:5L64|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:6H39|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:6HTB|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:6HTC|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HUU|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HW7|rcsb pdb:6HV4|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|rcsb pdb:1FNT|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:2ZCY|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:6ZP6|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4G4S|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QLV|rcsb pdb:4QZ2|rcsb pdb:4QW7|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QZ7|rcsb pdb:4QWI|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4QWJ|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4QWK|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4QWL|rcsb pdb:4X6Z|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4Y69|rcsb pdb:4QWU|rcsb pdb:4Y6A|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4Y6V|rcsb pdb:4QZ1|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:6ZP8|rcsb pdb:7LS5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4Y7X|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:4YA3|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|ensemblfungi:YFR050C(gene)|ensemblfungi:YFR050C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|refseq:NP_116708.1|sgd:S000001946|mint:P30657|dip:DIP-2807N	-	crc64:0EA42A599E2B2E2A	crc64:E585BB3B5D0C8E2C	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:y7+7rEZc9fqBZrHR4CvsFLoT0O4559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	uniprotkb:P43588	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	intact:EBI-11219|uniprotkb:Q8J0T5|uniprotkb:D6VTN4|ensemblfungi:YFR004W	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:rpn11_yeast(display_long)|uniprotkb:YFR004W(locus name)|uniprotkb:RPN11(gene name)|psi-mi:RPN11(display_short)|uniprotkb:MPR1(gene name synonym)|uniprotkb:Protein MPR1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	ensemblfungi:YFR004W(gene)|ensemblfungi:YFR004W_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016559"(peroxisome fission)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070628"(proteasome binding)|go:"GO:1902906"(proteasome storage granule assembly)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|go:"GO:0070122"(isopeptidase activity)|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_116659.1|sgd:S000001900|mint:P43588|dip:DIP-1573N	-	crc64:0EA42A599E2B2E2A	crc64:9DDE8BD74890894D	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:f3lAMY9siMcO2dAOfKvVrvKzfNM559292	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	flag tag:?-?	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P53549	intact:EBI-19797	intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C	dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96	psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name)	psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	de et al. (2018)	pubmed:30309908|imex:IM-27185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20798754|wwpdb:6EF3|emdb:EMD-9042|emdb:EMD-9043|emdb:EMD-9044|emdb:EMD-9045|imex:IM-27185-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549	sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI	-	crc64:0EA42A599E2B2E2A	no-uniprot-update:obsolete protein	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/10/17	2018/10/22	rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292	rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932	rigid:CPsUzUqU+eyux+tLOLB49er1kgQ	false	-	-	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)