#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:C4QZQ7	uniprotkb:C4R009	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800218|ensemblfungi:CAY68833	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r009_kompg(display_long)|uniprotkb:PAS_chr2-1_0223(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY68833(transcript)|ensemblfungi:PAS_chr2-1_0223(gene)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002491113.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR023580|interpro:IPR020789|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:1ay4K0OWVYfU09LaWaEKYqDEXuk644223	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R1V1	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800134|ensemblfungi:CAY69475	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r1v1_kompg(display_long)|uniprotkb:PAS_chr2-2_0434(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY69475(transcript)|ensemblfungi:PAS_chr2-2_0434(gene)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002491755.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR020708|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR028363|interpro:IPR036161|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:sOgXLbXs4iRGdaUFfb88ZVm1W98644223	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R273	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800178|ensemblfungi:CAY69597	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r273_kompg(display_long)|uniprotkb:PAS_chr2-2_0309(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY69597(transcript)|ensemblfungi:PAS_chr2-2_0309(gene)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002491877.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR005570(RNA polymerase, Rpb8)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:MnvasHhqga4MIKsh8kH1/bpM0wc644223	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R2U9	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800081|ensemblfungi:CAY69823	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r2u9_kompg(display_long)|uniprotkb:PAS_chr2-2_0104(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|ensemblfungi:CAY69823(transcript)|ensemblfungi:PAS_chr2-2_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|rcsb pdb:6INQ|refseq:XP_002492103.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR010997(HRDC-like)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR038324|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:/017Xpkf83C3N7U8UYAXzDWDlv8644223	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R3P8	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800108|ensemblfungi:CAY70112	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r3p8_kompg(display_long)|uniprotkb:PAS_chr3_0157(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6J50|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J51|ensemblfungi:CAY70112(transcript)|ensemblfungi:PAS_chr3_0157(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|rcsb pdb:6INQ|refseq:XP_002492363.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR036710|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR020608|interpro:IPR035913|interpro:IPR020609|interpro:IPR039531|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:uvHyo3JNliA/f1LdlRdTrLHAhu8644223	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R3Z5	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800241|ensemblfungi:CAY70274	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r3z5_kompg(display_long)|uniprotkb:PAS_chr3_0244(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY70274(transcript)|ensemblfungi:PAS_chr3_0244(gene)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6INQ|refseq:XP_002492460.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR037685|interpro:IPR036603|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:Bcxi1i7CjZerdkNw1zlStjnDbGA644223	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R4Y0	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20799999|ensemblfungi:CAY70616	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r4y0_kompg(display_long)|uniprotkb:PAS_chr3_0568(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	interpro:IPR042102|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY70616(transcript)|ensemblfungi:PAS_chr3_0568(gene)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002492795.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR038593|interpro:IPR038120|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:/Iegq8f+rYdUcNLjKKqdngz4RxI644223	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R7L2	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800059|ensemblfungi:CAY71587	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r7l2_kompg(display_long)|uniprotkb:PAS_chr4_0344(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY71587(transcript)|ensemblfungi:PAS_chr4_0344(gene)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6INQ|refseq:XP_002493766.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:aRUBPn6vT0brJH8ce/7n4CfRPV8644223	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:C4R9A1	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800159|ensemblfungi:CAY72176	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:c4r9a1_kompg(display_long)|uniprotkb:PAS_chr4_0906(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CAY72176(transcript)|ensemblfungi:PAS_chr4_0906(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0010590"(regulation of septum digestion after cytokinesis)|go:"GO:0097394"(telomeric repeat-containing RNA transcription by RNA polymerase II)|rcsb pdb:6INQ|refseq:XP_002494355.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036898|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR003029(S1, RNA binding)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:uE/3Z3mElfHD6zyWFofgkpflFOg644223	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:F2QMI1	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800261|ensemblfungi:CCA36628	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:f2qmi1_kompc(display_long)|uniprotkb:RPC10(gene name)|psi-mi:RPC10(display_short)|uniprotkb:PP7435_Chr1-0476(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:981350(kompc)|taxid:981350("Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CCA36628(transcript)|ensemblfungi:PP7435_CHR1-0476(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:6INQ|rcsb pdb:5XOG|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:XNaJRCB6Mz0dez4DoFiRGfxeoZA981350	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:F2QPE6	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-20800198|ensemblfungi:CCA37274	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:f2qpe6_kompc(display_long)|uniprotkb:RPB9(gene name)|psi-mi:RPB9(display_short)|uniprotkb:PP7435_Chr1-1144(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:981350(kompc)|taxid:981350("Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|ensemblfungi:CCA37274(transcript)|ensemblfungi:PP7435_CHR1-1144(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:6INQ|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|interpro:IPR019761|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR034012|interpro:IPR001222(Zinc finger, TFIIS-type)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:K8GCq9GcWsMRVlapEcuaLTOLJfc981350	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:P04908	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:4Qno1mMYZB6FdNoojrzulWLVq849606	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	2	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:P06899	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	2	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:P84243	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	2	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:C4QZQ7	uniprotkb:P62805	intact:EBI-20800027|ensemblfungi:CAY68731	intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567	psi-mi:c4qzq7_kompg(display_long)|uniprotkb:PAS_chr2-1_0125(locus name)	psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Kujirai et al. (2018)	pubmed:30287617|imex:IM-26718	taxid:644223(picpg)|taxid:644223("Komagataella pastoris (strain GS115 / ATCC 20864)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20800289|wwpdb:6A5O|wwpdb:6A5T|wwpdb:6A5L|wwpdb:6A5V|emdb:EMD-6981|emdb:EMD-6982|emdb:EMD-6983|emdb:EMD-6985|emdb:EMD-6986|wwpdb:6A5U|wwpdb:6A5R|emdb:EMD-6980|emdb:EMD-6984|wwpdb:6A5P|imex:IM-26718-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|ensemblfungi:CAY68731(transcript)|ensemblfungi:PAS_chr2-1_0125(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6INQ|refseq:XP_002491011.1|rcsb pdb:5X4Z|rcsb pdb:5X50|rcsb pdb:5X51|rcsb pdb:5XOG|rcsb pdb:5XON|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U	ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225	-	-	-	figure legend:Fig 1A, Table S1-S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/10/24	2018/10/24	rogid:gcT/MsMEB3P8v3j3Pppq08HpzZU644223	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606	rigid:87BNOQXXpArE2suhdzZvU/5G5eU	false	-	-	1	2	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)