#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06881	uniprotkb:Q16602	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-962878|ensembl:ENSP00000376177|ensembl:ENSP00000386972|ensembl:ENSP00000387190|uniprotkb:A8KAD3|uniprotkb:A8K6G5|uniprotkb:Q53S02|uniprotkb:Q53TS5	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:calrl_human(display_long)|uniprotkb:CALCRL(gene name)|psi-mi:CALCRL(display_short)|uniprotkb:CGRPR(gene name synonym)|uniprotkb:Calcitonin receptor-like receptor(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25750477|emdb:EMD-8978|wwpdb:6E3Y|imex:IM-28263-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003287(GPCR, family 2, calcitonin receptor-like)|interpro:IPR003289(GPCR, family 2, calcitonin gene-related peptide, type 1 receptor)|interpro:IPR017981|interpro:IPR017983|interpro:IPR036445|rcsb pdb:3AQF|rcsb pdb:3N7P|rcsb pdb:3N7R|rcsb pdb:3N7S|go:"GO:1990410"(adrenomedullin receptor signaling pathway)|rcsb pdb:4RWF|rcsb pdb:4RWG|rcsb pdb:5V6Y|rcsb pdb:6D1U|rcsb pdb:6E3Y|rcsb pdb:6UMG|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6V2E|rcsb pdb:6ZHO|rcsb pdb:6ZIS|rcsb pdb:7KNT|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|ensembl:ENSG00000064989(gene)|ensembl:ENST00000392370(transcript)|ensembl:ENST00000409998(transcript)|ensembl:ENST00000410068(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001605"(adrenomedullin receptor activity)|go:"GO:0001635"(calcitonin gene-related peptide receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004948"(calcitonin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0015031"(protein transport)|go:"GO:0031623"(receptor internalization)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071329"(cellular response to sucrose stimulus)|go:"GO:1903143"(adrenomedullin receptor complex)|go:"GO:1990406"(CGRP receptor complex)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|go:"GO:1990409"(adrenomedullin binding)|go:"GO:0005886"(plasma membrane)|refseq:NP_005786.1|refseq:NP_001258680.1|dip:DIP-37674N	-	-	-	figure legend:Fig 1, Extended Data Fig 1, Supplementary Information Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/07	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:CezdatTOyGz/AEKWvRS/lTOrl9A9606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	flag tag:n-n|his tag:c-c|binding-associated region:22-461	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P06881	uniprotkb:P62873	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-357130|ensembl:ENSP00000367872|ensembl:ENSP00000481878|uniprotkb:P04901|uniprotkb:P04697|uniprotkb:B1AJZ7|uniprotkb:Q1RMY8	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:gbb1_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25750477|emdb:EMD-8978|wwpdb:6E3Y|imex:IM-28263-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62873|rcsb pdb:4KFM|rcsb pdb:4PNK|rcsb pdb:5HE0|rcsb pdb:5HE1|rcsb pdb:5HE2|rcsb pdb:5HE3|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UKM|rcsb pdb:5UZ7|rcsb pdb:6B3J|rcsb pdb:6CRK|rcsb pdb:6D9H|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6E3Y|rcsb pdb:6EG8|rcsb pdb:6G79|rcsb pdb:6GDG|rcsb pdb:6KPF|rcsb pdb:6KPG|go:"GO:1903561"(extracellular vesicle)|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6M8S|rcsb pdb:6N4B|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6OIJ|rcsb pdb:6OIK|rcsb pdb:6OMM|rcsb pdb:6ORV|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VMS|rcsb pdb:6VN7|rcsb pdb:6WHA|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:6XOX|rcsb pdb:7AUE|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX4|rcsb pdb:7D76|rcsb pdb:7D77|rcsb pdb:7D7M|rcsb pdb:7DFL|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7E9H|rcsb pdb:7CX3|rcsb pdb:7EB2|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7JVR|rcsb pdb:7K7L|rcsb pdb:7K7Z|rcsb pdb:7KH0|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7L1U|rcsb pdb:7L1V|rcsb pdb:7LCI|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-381676|reactome:R-HSA-381753|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|ensembl:ENST00000610897(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097381"(photoreceptor disc membrane)|ensembl:ENSG00000078369(gene)|ensembl:ENST00000378609(transcript)|refseq:NP_001269467.1|refseq:NP_001269468.1|dip:DIP-599N|refseq:NP_002065.1|refseq:XP_016856548.1|refseq:XP_016856549.1|refseq:XP_016856550.1	-	-	-	figure legend:Fig 1, Extended Data Fig 1, Supplementary Information Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/07	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk9606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	binding-associated region:2-340|his tag:?-?	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P06881	uniprotkb:P59768	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-602681|uniprotkb:Q6P9A9|uniprotkb:Q5JPE2|ensembl:ENSP00000334448|ensembl:ENSP00000451102|ensembl:ENSP00000451231|ensembl:ENSP00000451576|ensembl:ENSP00000452014|ensembl:ENSP00000484021	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:gbg2_human(display_long)|uniprotkb:G gamma-I(gene name synonym)|uniprotkb:GNG2(gene name)|psi-mi:GNG2(display_short)	psi-mi:"MI:0410"(3D electron microscopy)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25750477|emdb:EMD-8978|wwpdb:6E3Y|imex:IM-28263-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	refseq:NP_001230702.1|refseq:NP_001230703.1|refseq:NP_444292.1|refseq:XP_011535148.1|refseq:XP_016876865.1|refseq:XP_016876866.1|refseq:XP_006720236.1|dip:DIP-33949N|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VMS|rcsb pdb:6VN7|rcsb pdb:6WHA|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WWZ|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:6XOX|rcsb pdb:7AUE|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7D76|rcsb pdb:7D77|rcsb pdb:7D7M|rcsb pdb:7DFL|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7E9H|rcsb pdb:7EB2|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7JVR|rcsb pdb:7K7L|rcsb pdb:7K7Z|rcsb pdb:7KH0|rcsb pdb:7L1U|rcsb pdb:7L1V|rcsb pdb:7LCI|rcsb pdb:7MBX|rcsb pdb:7MBY|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|ensembl:ENSG00000186469(gene)|ensembl:ENST00000335281(transcript)|ensembl:ENST00000554736(transcript)|ensembl:ENST00000555472(transcript)|ensembl:ENST00000556752(transcript)|ensembl:ENST00000556766(transcript)|ensembl:ENST00000615906(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6M8S|rcsb pdb:6N4B|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6OIJ|rcsb pdb:6OIK|rcsb pdb:6OMM|rcsb pdb:6ORV|rcsb pdb:6K42|rcsb pdb:6OS9|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|rcsb pdb:4KFM|rcsb pdb:5HE0|rcsb pdb:5HE1|rcsb pdb:5HE2|rcsb pdb:5HE3|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UKM|rcsb pdb:5UZ7|rcsb pdb:6B3J|rcsb pdb:6CRK|rcsb pdb:6D9H|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6E3Y|rcsb pdb:6EG8|rcsb pdb:6G79|rcsb pdb:6GDG|rcsb pdb:6K41	-	-	-	figure legend:Fig 1, Extended Data Fig 1, Supplementary Information Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/07	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:8asTjDtSU6sCPSMwcXMbV340Rt49606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	his tag:n-n	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P06881	uniprotkb:P63092	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-1047114|uniprotkb:P04895|uniprotkb:Q12927|uniprotkb:Q5JWD2|uniprotkb:Q5JWD4|uniprotkb:Q5JWD5|uniprotkb:Q6NR75|uniprotkb:Q6NXS0|uniprotkb:Q8TBC0|uniprotkb:Q96H70|uniprotkb:Q14433|uniprotkb:Q32P26|uniprotkb:E1P5G5|ensembl:ENSP00000360126|uniprotkb:A6NI00|intact:EBI-10977858	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:gnas2_human(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:GSP(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25750477|emdb:EMD-8978|wwpdb:6E3Y|imex:IM-28263-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	refseq:NP_001070958.1|refseq:NP_001296769.1|refseq:NP_536350.2|refseq:NP_000507.1|refseq:NP_001070956.1|refseq:NP_001070957.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371085(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63092|rcsb pdb:5G53|rcsb pdb:5UZ7|rcsb pdb:5VAI|rcsb pdb:6AU6|rcsb pdb:6B3J|rcsb pdb:6E3Y|rcsb pdb:6E67|rcsb pdb:6EG8|rcsb pdb:6GDG|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LPB|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6ORV|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VN7|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XOX|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7BPH|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D7M|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7KH0|rcsb pdb:7LCI|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821|refseq:NP_536351.1	-	-	-	figure legend:Fig 1, Extended Data Fig 1, Supplementary Information Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/07	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:fUnrdxwx4bBAqE3iO2cCB3UInyg9606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P06881	uniprotkb:O60894	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-962893|ensembl:ENSP00000254661|uniprotkb:Q6FGS5	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:ramp1_human(display_long)|uniprotkb:RAMP1(gene name)|psi-mi:RAMP1(display_short)|uniprotkb:Calcitonin-receptor-like receptor activity-modifying protein 1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25750477|emdb:EMD-8978|wwpdb:6E3Y|imex:IM-28263-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	ensembl:ENSG00000132329(gene)|ensembl:ENST00000254661(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001635"(calcitonin gene-related peptide receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0015026"(coreceptor activity)|go:"GO:0015031"(protein transport)|go:"GO:0031623"(receptor internalization)|go:"GO:0005886"(plasma membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0043235"(receptor complex)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0097643"(amylin receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:0150056"(amylin receptor complex 1)|go:"GO:1990406"(CGRP receptor complex)|go:"GO:1990407"(calcitonin gene-related peptide binding)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|interpro:IPR006985(Receptor activity modifying protein)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|interpro:IPR038126|rcsb pdb:2YX8|rcsb pdb:3N7P|rcsb pdb:3N7R|rcsb pdb:3N7S|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|rcsb pdb:4RWG|rcsb pdb:5V6Y|rcsb pdb:6D1U|rcsb pdb:6E3Y|rcsb pdb:6UMG|rcsb pdb:6ZHO|go:"GO:0009986"(cell surface)|rcsb pdb:6ZIS|rcsb pdb:7KNT|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_005846.1|dip:DIP-37675N	-	-	-	figure legend:Fig 1, Extended Data Fig 1, Supplementary Information Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/07	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:AjPlwP60HYwVhzaZc86mkP6XjYQ9606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P06881	uniprotkb:Q16602	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-962878|ensembl:ENSP00000376177|ensembl:ENSP00000386972|ensembl:ENSP00000387190|uniprotkb:A8KAD3|uniprotkb:A8K6G5|uniprotkb:Q53S02|uniprotkb:Q53TS5	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:calrl_human(display_long)|uniprotkb:CALCRL(gene name)|psi-mi:CALCRL(display_short)|uniprotkb:CGRPR(gene name synonym)|uniprotkb:Calcitonin receptor-like receptor(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25751555|imex:IM-28263-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003287(GPCR, family 2, calcitonin receptor-like)|interpro:IPR003289(GPCR, family 2, calcitonin gene-related peptide, type 1 receptor)|interpro:IPR017981|interpro:IPR017983|interpro:IPR036445|rcsb pdb:3AQF|rcsb pdb:3N7P|rcsb pdb:3N7R|rcsb pdb:3N7S|go:"GO:1990410"(adrenomedullin receptor signaling pathway)|rcsb pdb:4RWF|rcsb pdb:4RWG|rcsb pdb:5V6Y|rcsb pdb:6D1U|rcsb pdb:6E3Y|rcsb pdb:6UMG|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6V2E|rcsb pdb:6ZHO|rcsb pdb:6ZIS|rcsb pdb:7KNT|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|ensembl:ENSG00000064989(gene)|ensembl:ENST00000392370(transcript)|ensembl:ENST00000409998(transcript)|ensembl:ENST00000410068(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001605"(adrenomedullin receptor activity)|go:"GO:0001635"(calcitonin gene-related peptide receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004948"(calcitonin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0015031"(protein transport)|go:"GO:0031623"(receptor internalization)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071329"(cellular response to sucrose stimulus)|go:"GO:1903143"(adrenomedullin receptor complex)|go:"GO:1990406"(CGRP receptor complex)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|go:"GO:1990409"(adrenomedullin binding)|go:"GO:0005886"(plasma membrane)|refseq:NP_005786.1|refseq:NP_001258680.1|dip:DIP-37674N	-	-	-	figure legend:Extended Data Fig 2c, d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/08	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:CezdatTOyGz/AEKWvRS/lTOrl9A9606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	binding-associated region:22-461|flag tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P06881	uniprotkb:P62873	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-357130|ensembl:ENSP00000367872|ensembl:ENSP00000481878|uniprotkb:P04901|uniprotkb:P04697|uniprotkb:B1AJZ7|uniprotkb:Q1RMY8	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:gbb1_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25751555|imex:IM-28263-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62873|rcsb pdb:4KFM|rcsb pdb:4PNK|rcsb pdb:5HE0|rcsb pdb:5HE1|rcsb pdb:5HE2|rcsb pdb:5HE3|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UKM|rcsb pdb:5UZ7|rcsb pdb:6B3J|rcsb pdb:6CRK|rcsb pdb:6D9H|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6E3Y|rcsb pdb:6EG8|rcsb pdb:6G79|rcsb pdb:6GDG|rcsb pdb:6KPF|rcsb pdb:6KPG|go:"GO:1903561"(extracellular vesicle)|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6M8S|rcsb pdb:6N4B|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6OIJ|rcsb pdb:6OIK|rcsb pdb:6OMM|rcsb pdb:6ORV|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VMS|rcsb pdb:6VN7|rcsb pdb:6WHA|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:6XOX|rcsb pdb:7AUE|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX4|rcsb pdb:7D76|rcsb pdb:7D77|rcsb pdb:7D7M|rcsb pdb:7DFL|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7E9H|rcsb pdb:7CX3|rcsb pdb:7EB2|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7JVR|rcsb pdb:7K7L|rcsb pdb:7K7Z|rcsb pdb:7KH0|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7L1U|rcsb pdb:7L1V|rcsb pdb:7LCI|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-381676|reactome:R-HSA-381753|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|ensembl:ENST00000610897(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097381"(photoreceptor disc membrane)|ensembl:ENSG00000078369(gene)|ensembl:ENST00000378609(transcript)|refseq:NP_001269467.1|refseq:NP_001269468.1|dip:DIP-599N|refseq:NP_002065.1|refseq:XP_016856548.1|refseq:XP_016856549.1|refseq:XP_016856550.1	-	-	-	figure legend:Extended Data Fig 2c, d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/08	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk9606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	binding-associated region:2-340|his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P06881	uniprotkb:P59768	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-602681|uniprotkb:Q6P9A9|uniprotkb:Q5JPE2|ensembl:ENSP00000334448|ensembl:ENSP00000451102|ensembl:ENSP00000451231|ensembl:ENSP00000451576|ensembl:ENSP00000452014|ensembl:ENSP00000484021	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:gbg2_human(display_long)|uniprotkb:G gamma-I(gene name synonym)|uniprotkb:GNG2(gene name)|psi-mi:GNG2(display_short)	psi-mi:"MI:0071"(molecular sieving)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25751555|imex:IM-28263-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	refseq:NP_001230702.1|refseq:NP_001230703.1|refseq:NP_444292.1|refseq:XP_011535148.1|refseq:XP_016876865.1|refseq:XP_016876866.1|refseq:XP_006720236.1|dip:DIP-33949N|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VMS|rcsb pdb:6VN7|rcsb pdb:6WHA|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WWZ|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:6XOX|rcsb pdb:7AUE|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7D76|rcsb pdb:7D77|rcsb pdb:7D7M|rcsb pdb:7DFL|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7E9H|rcsb pdb:7EB2|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7JVR|rcsb pdb:7K7L|rcsb pdb:7K7Z|rcsb pdb:7KH0|rcsb pdb:7L1U|rcsb pdb:7L1V|rcsb pdb:7LCI|rcsb pdb:7MBX|rcsb pdb:7MBY|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|ensembl:ENSG00000186469(gene)|ensembl:ENST00000335281(transcript)|ensembl:ENST00000554736(transcript)|ensembl:ENST00000555472(transcript)|ensembl:ENST00000556752(transcript)|ensembl:ENST00000556766(transcript)|ensembl:ENST00000615906(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6M8S|rcsb pdb:6N4B|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6OIJ|rcsb pdb:6OIK|rcsb pdb:6OMM|rcsb pdb:6ORV|rcsb pdb:6K42|rcsb pdb:6OS9|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|rcsb pdb:4KFM|rcsb pdb:5HE0|rcsb pdb:5HE1|rcsb pdb:5HE2|rcsb pdb:5HE3|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UKM|rcsb pdb:5UZ7|rcsb pdb:6B3J|rcsb pdb:6CRK|rcsb pdb:6D9H|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6E3Y|rcsb pdb:6EG8|rcsb pdb:6G79|rcsb pdb:6GDG|rcsb pdb:6K41	-	-	-	figure legend:Extended Data Fig 2c, d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/08	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:8asTjDtSU6sCPSMwcXMbV340Rt49606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P06881	uniprotkb:P63092	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-1047114|uniprotkb:P04895|uniprotkb:Q12927|uniprotkb:Q5JWD2|uniprotkb:Q5JWD4|uniprotkb:Q5JWD5|uniprotkb:Q6NR75|uniprotkb:Q6NXS0|uniprotkb:Q8TBC0|uniprotkb:Q96H70|uniprotkb:Q14433|uniprotkb:Q32P26|uniprotkb:E1P5G5|ensembl:ENSP00000360126|uniprotkb:A6NI00|intact:EBI-10977858	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:gnas2_human(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:GSP(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25751555|imex:IM-28263-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	refseq:NP_001070958.1|refseq:NP_001296769.1|refseq:NP_536350.2|refseq:NP_000507.1|refseq:NP_001070956.1|refseq:NP_001070957.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371085(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63092|rcsb pdb:5G53|rcsb pdb:5UZ7|rcsb pdb:5VAI|rcsb pdb:6AU6|rcsb pdb:6B3J|rcsb pdb:6E3Y|rcsb pdb:6E67|rcsb pdb:6EG8|rcsb pdb:6GDG|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LPB|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6ORV|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VN7|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XOX|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7BPH|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D7M|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7KH0|rcsb pdb:7LCI|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821|refseq:NP_536351.1	-	-	-	figure legend:Extended Data Fig 2c, d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/08	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:fUnrdxwx4bBAqE3iO2cCB3UInyg9606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	-	-	-	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P06881	uniprotkb:O60894	intact:EBI-962928|ensembl:ENSP00000354286|ensembl:ENSP00000417833|uniprotkb:Q93048|uniprotkb:Q9UCP0	intact:EBI-962893|ensembl:ENSP00000254661|uniprotkb:Q6FGS5	psi-mi:calca_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)|uniprotkb:Calcitonin gene-related peptide I(gene name synonym)|uniprotkb:Alpha-type CGRP(gene name synonym)	psi-mi:ramp1_human(display_long)|uniprotkb:RAMP1(gene name)|psi-mi:RAMP1(display_short)|uniprotkb:Calcitonin-receptor-like receptor activity-modifying protein 1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Liang et al. (2018)	pubmed:30209400|imex:IM-28263	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25751555|imex:IM-28263-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000361010(transcript)|ensembl:ENST00000486207(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001944"(vasculature development)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|ensembl:ENSG00000110680(gene)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031623"(receptor internalization)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042311"(vasodilation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|interpro:IPR001693(Calcitonin-like)|interpro:IPR015476(Calcitonin gene related peptide)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|rcsb pdb:1LS7|rcsb pdb:6E3Y|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_001029125.1	ensembl:ENSG00000132329(gene)|ensembl:ENST00000254661(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001635"(calcitonin gene-related peptide receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0015026"(coreceptor activity)|go:"GO:0015031"(protein transport)|go:"GO:0031623"(receptor internalization)|go:"GO:0005886"(plasma membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0043235"(receptor complex)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0097643"(amylin receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0097647"(amylin receptor signaling pathway)|go:"GO:0150056"(amylin receptor complex 1)|go:"GO:1990406"(CGRP receptor complex)|go:"GO:1990407"(calcitonin gene-related peptide binding)|go:"GO:1990408"(calcitonin gene-related peptide receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|interpro:IPR006985(Receptor activity modifying protein)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|interpro:IPR038126|rcsb pdb:2YX8|rcsb pdb:3N7P|rcsb pdb:3N7R|rcsb pdb:3N7S|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|rcsb pdb:4RWG|rcsb pdb:5V6Y|rcsb pdb:6D1U|rcsb pdb:6E3Y|rcsb pdb:6UMG|rcsb pdb:6ZHO|go:"GO:0009986"(cell surface)|rcsb pdb:6ZIS|rcsb pdb:7KNT|rcsb pdb:7KNU|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|refseq:NP_005846.1|dip:DIP-37675N	-	-	-	figure legend:Extended Data Fig 2c, d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2018/10/02	2020/07/08	rogid:gM1XX8NUOJKraSnqNoX6NO0oH8E9606	rogid:AjPlwP60HYwVhzaZc86mkP6XjYQ9606	rigid:wx75x6GXWf+I0JYL2/JMsr7+HBk	false	binding-associated region:83-119	-	-	-	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)