#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8IIJ8 uniprotkb:Q8IKC8 intact:EBI-827905|ensemblprotists:CZT98829 intact:EBI-823508|ensemblprotists:CZU00408 psi-mi:q8iij8_plaf7(display_long)|uniprotkb:PF3D7_1116800(orf name) psi-mi:q8ikc8_plaf7(display_long)|uniprotkb:PF3D7_1471100(orf name) psi-mi:"MI:0410"(3D electron microscopy) Ho et al. (2018) pubmed:30150771|imex:IM-26825 taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20738603|imex:IM-26825-1|emdb:EMD-8951|emdb:EMD-8952|wwpdb:6E10|wwpdb:6E11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:XP_001347846.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR028299|rcsb pdb:4IOD|rcsb pdb:4IRF|interpro:IPR036628|rcsb pdb:6E10|rcsb pdb:6E11|interpro:IPR041546|ensemblprotists:CZT98829(transcript)|ensemblprotists:PF3D7_1116800(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0020007"(apical complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0097619"(PTEX complex) refseq:XP_001348852.1|dip:DIP-42909N|ensemblprotists:CZU00408(transcript)|ensemblprotists:PF3D7_1471100(gene)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0097619"(PTEX complex)|rcsb pdb:6E10|rcsb pdb:6E11 - - - figure legend:Fig. 1, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") - 2018/09/11 2018/09/11 rogid:moSqM3k4ToZ7k86HPMX8Jd21KiA36329 rogid:bFAzNnIs/b7tvgsvMjrEjbhQGy036329 rigid:AJCSB1BVzas0Oau7cT7pbn30gjo false flag tag:c-c - 6 7 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q8IIJ8 uniprotkb:Q8ILA1 intact:EBI-827905|ensemblprotists:CZT98829 intact:EBI-823576|ensemblprotists:CZU00061 psi-mi:q8iij8_plaf7(display_long)|uniprotkb:PF3D7_1116800(orf name) psi-mi:q8ila1_plaf7(display_long)|uniprotkb:PF3D7_1436300(orf name) psi-mi:"MI:0410"(3D electron microscopy) Ho et al. (2018) pubmed:30150771|imex:IM-26825 taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20738603|imex:IM-26825-1|emdb:EMD-8951|emdb:EMD-8952|wwpdb:6E10|wwpdb:6E11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:XP_001347846.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR028299|rcsb pdb:4IOD|rcsb pdb:4IRF|interpro:IPR036628|rcsb pdb:6E10|rcsb pdb:6E11|interpro:IPR041546|ensemblprotists:CZT98829(transcript)|ensemblprotists:PF3D7_1116800(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0020007"(apical complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0097619"(PTEX complex) refseq:XP_001348518.1|dip:DIP-43130N|ensemblprotists:CZU00061(transcript)|ensemblprotists:PF3D7_1436300(gene)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0020007"(apical complex)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0097619"(PTEX complex)|rcsb pdb:6E10|rcsb pdb:6E11 - - - figure legend:Fig. 1, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") - 2018/09/11 2018/09/11 rogid:moSqM3k4ToZ7k86HPMX8Jd21KiA36329 rogid:Zl88nWg8wn/86/Tr5bVk1gP4VLU36329 rigid:AJCSB1BVzas0Oau7cT7pbn30gjo false flag tag:c-c - 6 7 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q8IIJ8 uniprotkb:Q8IJX8 intact:EBI-827905|ensemblprotists:CZT98829 intact:EBI-826658|ensemblprotists:CZT98311 psi-mi:q8iij8_plaf7(display_long)|uniprotkb:PF3D7_1116800(orf name) psi-mi:q8ijx8_plaf7(display_long)|uniprotkb:PF3D7_1006200(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ho et al. (2018) pubmed:30150771|imex:IM-26825 taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20738635|imex:IM-26825-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:XP_001347846.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR028299|rcsb pdb:4IOD|rcsb pdb:4IRF|interpro:IPR036628|rcsb pdb:6E10|rcsb pdb:6E11|interpro:IPR041546|ensemblprotists:CZT98829(transcript)|ensemblprotists:PF3D7_1116800(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0020007"(apical complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0097619"(PTEX complex) interpro:IPR002775(Alba, DNA/RNA-binding protein)|refseq:XP_001347348.1|interpro:IPR036882|interpro:IPR014560(Uncharacterised conserved protein UCP030333, DNA/RNA-binding Alba-related)|ensemblprotists:CZT98311(transcript)|ensemblprotists:PF3D7_1006200(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus) - - - figure legend:Extended Data Fig. 1e, f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") - 2018/09/11 2018/09/11 rogid:moSqM3k4ToZ7k86HPMX8Jd21KiA36329 rogid:qBApNxcHhUnedVFMgbVyYEGC6GY36329 rigid:5LBx2SPjoBiUF2s3DoGjzR4/KeQ false flag tag:c-c - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IIJ8 uniprotkb:Q8ILA1 intact:EBI-827905|ensemblprotists:CZT98829 intact:EBI-823576|ensemblprotists:CZU00061 psi-mi:q8iij8_plaf7(display_long)|uniprotkb:PF3D7_1116800(orf name) psi-mi:q8ila1_plaf7(display_long)|uniprotkb:PF3D7_1436300(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ho et al. (2018) pubmed:30150771|imex:IM-26825 taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20738635|imex:IM-26825-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:XP_001347846.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR028299|rcsb pdb:4IOD|rcsb pdb:4IRF|interpro:IPR036628|rcsb pdb:6E10|rcsb pdb:6E11|interpro:IPR041546|ensemblprotists:CZT98829(transcript)|ensemblprotists:PF3D7_1116800(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0020007"(apical complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0097619"(PTEX complex) refseq:XP_001348518.1|dip:DIP-43130N|ensemblprotists:CZU00061(transcript)|ensemblprotists:PF3D7_1436300(gene)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0020007"(apical complex)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0097619"(PTEX complex)|rcsb pdb:6E10|rcsb pdb:6E11 - - - figure legend:Extended Data Fig. 1e, f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") - 2018/09/11 2018/09/11 rogid:moSqM3k4ToZ7k86HPMX8Jd21KiA36329 rogid:Zl88nWg8wn/86/Tr5bVk1gP4VLU36329 rigid:5LBx2SPjoBiUF2s3DoGjzR4/KeQ false flag tag:c-c - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q8IIJ8 uniprotkb:Q8IKC8 intact:EBI-827905|ensemblprotists:CZT98829 intact:EBI-823508|ensemblprotists:CZU00408 psi-mi:q8iij8_plaf7(display_long)|uniprotkb:PF3D7_1116800(orf name) psi-mi:q8ikc8_plaf7(display_long)|uniprotkb:PF3D7_1471100(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ho et al. (2018) pubmed:30150771|imex:IM-26825 taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20738635|imex:IM-26825-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:XP_001347846.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR028299|rcsb pdb:4IOD|rcsb pdb:4IRF|interpro:IPR036628|rcsb pdb:6E10|rcsb pdb:6E11|interpro:IPR041546|ensemblprotists:CZT98829(transcript)|ensemblprotists:PF3D7_1116800(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0020007"(apical complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0097619"(PTEX complex) refseq:XP_001348852.1|dip:DIP-42909N|ensemblprotists:CZU00408(transcript)|ensemblprotists:PF3D7_1471100(gene)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0097619"(PTEX complex)|rcsb pdb:6E10|rcsb pdb:6E11 - - - figure legend:Extended Data Fig. 1e, f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") - 2018/09/11 2018/09/11 rogid:moSqM3k4ToZ7k86HPMX8Jd21KiA36329 rogid:bFAzNnIs/b7tvgsvMjrEjbhQGy036329 rigid:5LBx2SPjoBiUF2s3DoGjzR4/KeQ false flag tag:c-c - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q8IIJ8 uniprotkb:Q8I2X4 intact:EBI-827905|ensemblprotists:CZT98829 intact:EBI-825198|ensemblprotists:CAD51861 psi-mi:q8iij8_plaf7(display_long)|uniprotkb:PF3D7_1116800(orf name) psi-mi:q8i2x4_plaf7(display_long)|uniprotkb:PF3D7_0917900(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ho et al. (2018) pubmed:30150771|imex:IM-26825 taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20738635|imex:IM-26825-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:XP_001347846.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR028299|rcsb pdb:4IOD|rcsb pdb:4IRF|interpro:IPR036628|rcsb pdb:6E10|rcsb pdb:6E11|interpro:IPR041546|ensemblprotists:CZT98829(transcript)|ensemblprotists:PF3D7_1116800(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0020007"(apical complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0097619"(PTEX complex) interpro:IPR043129|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|refseq:XP_001352050.1|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|ensemblprotists:CAD51861(transcript)|ensemblprotists:PF3D7_0917900(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding) - - - figure legend:Extended Data Fig. 1e, f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:36329(plaf7)|taxid:36329("Plasmodium falciparum (isolate 3D7)") - 2018/09/11 2018/09/11 rogid:moSqM3k4ToZ7k86HPMX8Jd21KiA36329 rogid:vESr33zpjGABbo9zQ0ewlRr8rRY36329 rigid:5LBx2SPjoBiUF2s3DoGjzR4/KeQ false flag tag:c-c - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology)