#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O00429-3 uniprotkb:Q96C03-1 intact:EBI-6896746|ensembl:ENSP00000415131|intact:EBI-8515094|intact:MINT-1394240|intact:EBI-8515126|intact:EBI-8514952|intact:EBI-8515016|intact:EBI-8514903|intact:EBI-8514984|intact:EBI-8515069 intact:EBI-20719773|ensembl:ENSP00000323591|ensembl:ENSP00000491181 psi-mi:o00429-3(display_long)|uniprotkb:DLP1a(isoform synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym) psi-mi:q96c03-1(display_long)|uniprotkb:MIEF2(gene name)|psi-mi:MIEF2(display_short)|uniprotkb:MID49(gene name synonym)|uniprotkb:SMCR7(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 49 kDa(gene name synonym)|uniprotkb:Mitochondrial elongation factor 2(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Kalia et al. (2018) pubmed:29899447|imex:IM-26855 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-20719771|imex:IM-26855-1|wwpdb:5WP9|emdb:EMD-8874 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087470(gene)|ensembl:ENST00000452533(transcript)|intact:EBI-724571(isoform-parent)|uniprotkb:O00429-3(isoform-parent) ensembl:ENSG00000177427(gene)|ensembl:ENSG00000284495(gene)|ensembl:ENST00000323019(transcript)|ensembl:ENST00000640122(transcript)|intact:EBI-750153(isoform-parent) - - - figure legend:Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/15 2018/09/21 rogid:mupIoP90J2TzjhVbd3DSB3q0elY9606 rogid:6/vE89OUApM4jmEn3byKeAkZKEw9606 rigid:wDVB/foNf6TDLd+sZ5Sw+r+deDA false - binding-associated region:126-454 8 8 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00429-3 uniprotkb:O00429-3 intact:EBI-6896746|ensembl:ENSP00000415131|intact:EBI-8515094|intact:MINT-1394240|intact:EBI-8515126|intact:EBI-8514952|intact:EBI-8515016|intact:EBI-8514903|intact:EBI-8514984|intact:EBI-8515069 intact:EBI-6896746|ensembl:ENSP00000415131|intact:EBI-8515094|intact:MINT-1394240|intact:EBI-8515126|intact:EBI-8514952|intact:EBI-8515016|intact:EBI-8514903|intact:EBI-8514984|intact:EBI-8515069 psi-mi:o00429-3(display_long)|uniprotkb:DLP1a(isoform synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym) psi-mi:o00429-3(display_long)|uniprotkb:DLP1a(isoform synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kalia et al. (2018) pubmed:29899447|imex:IM-26855 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-20719801|imex:IM-26855-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087470(gene)|ensembl:ENST00000452533(transcript)|intact:EBI-724571(isoform-parent)|uniprotkb:O00429-3(isoform-parent)|go:"GO:0051260"(protein homooligomerization) ensembl:ENSG00000087470(gene)|ensembl:ENST00000452533(transcript)|intact:EBI-724571(isoform-parent)|uniprotkb:O00429-3(isoform-parent) - - - figure legend:Extended Data Fig 8a-d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2018/08/15 2019/01/09 rogid:mupIoP90J2TzjhVbd3DSB3q0elY9606 rogid:mupIoP90J2TzjhVbd3DSB3q0elY9606 rigid:25RA7Shz2foZSRjY7BbU00KSCQs false mutation disrupting interaction:190-190 mutation decreasing interaction:221-221 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00429-3 uniprotkb:O00429-3 intact:EBI-6896746|ensembl:ENSP00000415131|intact:EBI-8515094|intact:MINT-1394240|intact:EBI-8515126|intact:EBI-8514952|intact:EBI-8515016|intact:EBI-8514903|intact:EBI-8514984|intact:EBI-8515069 intact:EBI-6896746|ensembl:ENSP00000415131|intact:EBI-8515094|intact:MINT-1394240|intact:EBI-8515126|intact:EBI-8514952|intact:EBI-8515016|intact:EBI-8514903|intact:EBI-8514984|intact:EBI-8515069 psi-mi:o00429-3(display_long)|uniprotkb:DLP1a(isoform synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym) psi-mi:o00429-3(display_long)|uniprotkb:DLP1a(isoform synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kalia et al. (2018) pubmed:29899447|imex:IM-26855 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-20719801|imex:IM-26855-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087470(gene)|ensembl:ENST00000452533(transcript)|intact:EBI-724571(isoform-parent)|uniprotkb:O00429-3(isoform-parent)|go:"GO:0051260"(protein homooligomerization) ensembl:ENSG00000087470(gene)|ensembl:ENST00000452533(transcript)|intact:EBI-724571(isoform-parent)|uniprotkb:O00429-3(isoform-parent) - - - figure legend:Extended Data Fig 8a-d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2018/08/15 2019/01/09 rogid:mupIoP90J2TzjhVbd3DSB3q0elY9606 rogid:mupIoP90J2TzjhVbd3DSB3q0elY9606 rigid:25RA7Shz2foZSRjY7BbU00KSCQs false mutation disrupting interaction:190-190 mutation disrupting interaction:362-362 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)