#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9EPK7 uniprotkb:Q8N4P3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-750003|ensembl:ENSP00000377814|ensembl:ENSP00000493549 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:mesh1_human(display_long)|uniprotkb:HDDC3(gene name)|psi-mi:HDDC3(display_short)|uniprotkb:MESH1(gene name synonym)|uniprotkb:HD domain-containing protein 3(gene name synonym)|uniprotkb:Metazoan SpoT homolog 1(gene name synonym)|uniprotkb:Penta-phosphate guanosine-3'-pyrophosphohydrolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168916|imex:IM-26378-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001273380.1|refseq:NP_940929.1|ensembl:ENSG00000184508(gene)|ensembl:ENST00000394272(transcript)|ensembl:ENST00000646620(transcript)|go:"GO:0008893"("guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity")|go:"GO:0046872"(metal ion binding)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|rcsb pdb:3NR1|rcsb pdb:5VXA - - - figure legend:Figure 1A, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:XVvrKb69+wdsrrj9sCG0YW5cQ5w9606 rigid:ngygWgcBG3EDVbpWi7vkinddp6k false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9NTM9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-714918|uniprotkb:Q5TCZ8|uniprotkb:Q9Y321|ensembl:ENSP00000359507 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:cutc_human(display_long)|uniprotkb:CUTC(gene name)|psi-mi:CUTC(display_short)|uniprotkb:CGI-32(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168916|imex:IM-26378-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSG00000119929(gene)|ensembl:ENST00000370476(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006825"(copper ion transport)|go:"GO:0051262"(protein tetramerization)|go:"GO:0055070"(copper ion homeostasis)|interpro:IPR005627(CutC)|interpro:IPR023648|interpro:IPR036822|mint:Q9NTM9|refseq:NP_057044.2|reactome:R-HSA-936837|rcsb pdb:3IWP - - - figure legend:Figure 1A, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:MkxQTQ5IGq+/IZzPy3wSurdtB6w9606 rigid:ngygWgcBG3EDVbpWi7vkinddp6k false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q53HV7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-749970|uniprotkb:O95862|uniprotkb:Q8NB71|uniprotkb:Q9BWC8|uniprotkb:A8K2K9|uniprotkb:Q0D2M0|ensembl:ENSP00000338606|ensembl:ENSP00000424191|ensembl:ENSP00000507590|ensembl:ENSP00000384828|intact:EBI-16429121 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:smug1_human(display_long)|uniprotkb:SMUG1(gene name)|psi-mi:SMUG1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168916|imex:IM-26378-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_055126.1|refseq:XP_011536411.1|refseq:XP_011536412.1|refseq:XP_011536413.1|refseq:XP_011536414.1|refseq:XP_011536415.1|refseq:XP_011536416.1|refseq:XP_011536417.1|refseq:XP_011536418.1|refseq:XP_011536419.1|refseq:XP_011536420.1|refseq:XP_011536421.1|refseq:XP_011536422.1|refseq:XP_011536423.1|refseq:NP_001230716.1|refseq:NP_001230717.1|refseq:NP_001230718.1|refseq:NP_001230719.1|refseq:NP_001230720.1|refseq:XP_006719382.1|refseq:XP_006719383.1|refseq:XP_006719384.1|refseq:XP_016874602.1|refseq:XP_016874603.1|refseq:XP_016874604.1|refseq:XP_016874605.1|refseq:XP_016874608.1|ensembl:ENSG00000123415(gene)|ensembl:ENST00000337581(transcript)|ensembl:ENST00000401977(transcript)|ensembl:ENST00000508394(transcript)|ensembl:ENST00000682136(transcript)|go:"GO:0000703"(oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0017065"(single-strand selective uracil DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045008"(depyrimidination)|interpro:IPR036895|interpro:IPR039134|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|refseq:XP_006719385.1|refseq:XP_011536424.1|refseq:XP_016874606.1|refseq:XP_016874607.1|refseq:XP_016874609.1 - - - figure legend:Figure 1A, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:spkw9KcBN2lpT8wBFBWzIdlhgtg9606 rigid:ngygWgcBG3EDVbpWi7vkinddp6k false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9BY41 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6598095|uniprotkb:A6ND12|uniprotkb:A6ND61|ensembl:ENSP00000362674|uniprotkb:A6NET3|uniprotkb:A8MQ62|uniprotkb:B4DKN0|uniprotkb:B4DV22|uniprotkb:Q86VC8|uniprotkb:Q9NP76|uniprotkb:Q9NYH4|uniprotkb:A6NJR3 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hdac8_human(display_long)|uniprotkb:HDAC8(gene name)|psi-mi:HDAC8(display_short)|uniprotkb:HDACL1(gene name synonym)|uniprotkb:CDA07(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168916|imex:IM-26378-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSG00000147099(gene)|ensembl:ENST00000373573(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR037138|mint:Q9BY41|rcsb pdb:1T64|rcsb pdb:1T67|rcsb pdb:1T69|rcsb pdb:1VKG|rcsb pdb:1W22|rcsb pdb:2V5W|rcsb pdb:2V5X|rcsb pdb:3EW8|rcsb pdb:3EWF|rcsb pdb:3EZP|rcsb pdb:3EZT|rcsb pdb:3F06|rcsb pdb:3F07|rcsb pdb:3F0R|rcsb pdb:3MZ3|rcsb pdb:3MZ4|rcsb pdb:3MZ6|rcsb pdb:3MZ7|rcsb pdb:3RQD|rcsb pdb:3SFF|interpro:IPR023801|rcsb pdb:3SFH|rcsb pdb:4QA0|rcsb pdb:4QA1|rcsb pdb:4QA2|rcsb pdb:4QA3|rcsb pdb:4QA4|rcsb pdb:4QA5|rcsb pdb:4QA6|rcsb pdb:4QA7|rcsb pdb:4RN0|rcsb pdb:4RN1|rcsb pdb:4RN2|rcsb pdb:5BWZ|rcsb pdb:5D1B|rcsb pdb:5D1C|rcsb pdb:5D1D|rcsb pdb:5DC5|rcsb pdb:5DC6|rcsb pdb:5DC7|rcsb pdb:5DC8|rcsb pdb:5FCW|rcsb pdb:5THS|rcsb pdb:5THT|rcsb pdb:5THU|rcsb pdb:5THV|rcsb pdb:5VI6|rcsb pdb:6HSK|rcsb pdb:6ODA|rcsb pdb:6ODB|rcsb pdb:6ODC|rcsb pdb:7JVU|rcsb pdb:7JVV|rcsb pdb:7JVW|reactome:R-HSA-2122947|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|refseq:NP_001159890.1|refseq:NP_001159891.1|refseq:NP_060956.1|refseq:NP_001159894.1|refseq:NP_001159920.1|refseq:NP_001159892.1 - - - figure legend:Figure 1A, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ox+oBoLdr03D6tPUroV2PpavrhE9606 rigid:ngygWgcBG3EDVbpWi7vkinddp6k false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P08397 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-9090148|uniprotkb:G3V1P4|uniprotkb:G5EA58|uniprotkb:A8K2L0|uniprotkb:Q16012|uniprotkb:P08396|ensembl:ENSP00000498786 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hem3_human(display_long)|uniprotkb:Hydroxymethylbilane synthase(gene name synonym)|uniprotkb:PBGD(gene name synonym)|uniprotkb:Pre-uroporphyrinogen synthase(gene name synonym)|uniprotkb:UPS(gene name synonym)|uniprotkb:HMBS(gene name)|psi-mi:HMBS(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168916|imex:IM-26378-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_000181.2|refseq:NP_001019553.1|refseq:NP_001245137.1|refseq:NP_001245138.1|refseq:XP_005271588.1|refseq:XP_005271589.1|refseq:XP_016873118.1|ensembl:ENSG00000256269(gene)|go:"GO:0004418"(hydroxymethylbilane synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0018160"(peptidyl-pyrromethane cofactor linkage)|interpro:IPR000860(Tetrapyrrole biosynthesis, hydroxymethylbilane synthase)|interpro:IPR022417|interpro:IPR022418|interpro:IPR022419|interpro:IPR036803|rcsb pdb:3ECR|ensembl:ENST00000652429(transcript)|rcsb pdb:5M6R|rcsb pdb:5M7F|rcsb pdb:7AAJ|rcsb pdb:7AAK|rcsb pdb:7CCX|rcsb pdb:7CCY|rcsb pdb:7CCZ|rcsb pdb:7CD0|reactome:R-HSA-189451|rcsb pdb:3EQ1 - - - figure legend:Figure 1A, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:aTjyl498kJtf2NyY0oQFyz00ogc9606 rigid:ngygWgcBG3EDVbpWi7vkinddp6k false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O14929 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168916|imex:IM-26378-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 - - - figure legend:Figure 1A, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rigid:ngygWgcBG3EDVbpWi7vkinddp6k false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q16576 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168916|imex:IM-26378-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - - figure legend:Figure 1A, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:ngygWgcBG3EDVbpWi7vkinddp6k false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P43490 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168916|imex:IM-26378-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N - - - figure legend:Figure 1A, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606 rigid:ngygWgcBG3EDVbpWi7vkinddp6k false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O60502 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-715814|uniprotkb:O75166|uniprotkb:Q86WV0|uniprotkb:Q8IV98|uniprotkb:Q9BVA5|uniprotkb:Q9HAR0|uniprotkb:B7WPB9|uniprotkb:D3DR79|uniprotkb:E9PGF9|ensembl:ENSP00000354850 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:oga_human(display_long)|uniprotkb:OGA(gene name)|psi-mi:OGA(display_short)|uniprotkb:Beta-N-acetylglucosaminidase(gene name synonym)|uniprotkb:Beta-N-acetylhexosaminidase(gene name synonym)|uniprotkb:Beta-hexosaminidase(gene name synonym)|uniprotkb:HEXC(gene name synonym)|uniprotkb:KIAA0679(gene name synonym)|uniprotkb:MEA5(gene name synonym)|uniprotkb:MGEA5(gene name synonym)|uniprotkb:Meningioma-expressed antigen 5(gene name synonym)|uniprotkb:N-acetyl-beta-D-glucosaminidase(gene name synonym)|uniprotkb:N-acetyl-beta-glucosaminidase(gene name synonym)|uniprotkb:Nuclear cytoplasmic O-GlcNAcase and acetyltransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168916|imex:IM-26378-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001135906.1|refseq:NP_036347.1|ensembl:ENSG00000198408(gene)|ensembl:ENST00000361464(transcript)|go:"GO:0004415"(hyalurononglucosaminidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006044"(N-acetylglucosamine metabolic process)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016231"(beta-N-acetylglucosaminidase activity)|go:"GO:0102166"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity")|go:"GO:0102167"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity")|go:"GO:0102571"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity")|interpro:IPR011496(Hyaluronidase eukaryotic/prokaryotic)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:2YDQ|rcsb pdb:5M7R|rcsb pdb:5M7S|rcsb pdb:5M7T|rcsb pdb:5M7U|rcsb pdb:5TKE|rcsb pdb:5UHK|rcsb pdb:5UHL|rcsb pdb:5UHO|rcsb pdb:5UHP|rcsb pdb:5UN8|rcsb pdb:5UN9|rcsb pdb:5VVO|rcsb pdb:5VVT|rcsb pdb:5VVU|rcsb pdb:5VVV|rcsb pdb:5VVX|rcsb pdb:6HKI|rcsb pdb:6PM9|go:"GO:0005634"(nucleus) - - - figure legend:Figure 1A, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:KEvP6+2BWwsxrs8hsIjQhKAQGVo9606 rigid:ngygWgcBG3EDVbpWi7vkinddp6k false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P68371 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168930|imex:IM-26378-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:figure 1A-2, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 rigid:HTozGVhNvRFsRNtin7k09OPPLd4 false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P68366 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|ensembl:ENSP00000248437|uniprotkb:B3KNQ6|intact:EBI-11134566 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168930|imex:IM-26378-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_005991.1|ensembl:ENSG00000127824(gene)|ensembl:ENST00000248437(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001265481.1 - - - figure legend:figure 1A-2, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606 rigid:HTozGVhNvRFsRNtin7k09OPPLd4 false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9UBQ0 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168930|imex:IM-26378-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N - - - figure legend:figure 1A-2, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:xjo28jAH7expkdli0DENjzLXpjw9606 rigid:HTozGVhNvRFsRNtin7k09OPPLd4 false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O75436 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168930|imex:IM-26378-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N - - - figure legend:figure 1A-2, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rigid:HTozGVhNvRFsRNtin7k09OPPLd4 false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q96QK1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168930|imex:IM-26378-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N - - - figure legend:figure 1A-2, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:EXkMduDQKNCdp876vGF5vna9t389606 rigid:HTozGVhNvRFsRNtin7k09OPPLd4 false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P31947 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168930|imex:IM-26378-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N - - - figure legend:figure 1A-2, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606 rigid:HTozGVhNvRFsRNtin7k09OPPLd4 false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q07960 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168930|imex:IM-26378-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_004299.1|refseq:XP_011518397.1|dip:DIP-6081N|ensembl:ENSG00000175220(gene)|ensembl:ENST00000311956(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696270 - - - figure legend:figure 1A-2, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ceA3oLsnddhLiSbylS89P64mYBo9606 rigid:HTozGVhNvRFsRNtin7k09OPPLd4 false protein a tag:?-?|his tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62826 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17168930|imex:IM-26378-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:figure 1A-2, Supp. file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/10 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:HTozGVhNvRFsRNtin7k09OPPLd4 false protein a tag:?-?|his tag:?-? mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CWZ3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1993805|uniprotkb:Q9D6U5|uniprotkb:Q3UT38|uniprotkb:Q6GTD4|uniprotkb:A0A023T672|ensembl:ENSMUSP00000143190 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rbm8a_mouse(display_long)|uniprotkb:Rbm8a(gene name)|psi-mi:Rbm8a(display_short)|uniprotkb:Rbm8(gene name synonym)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001095877.1|refseq:NP_080151.2|ensembl:ENSMUSG00000038374(gene)|ensembl:ENSMUST00000196456(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9CWZ3|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-975957 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q64378 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-492796|ensembl:ENSMUSP00000078382|ensembl:ENSMUSP00000110440|ensembl:ENSMUSP00000136245|ensembl:ENSMUSP00000156418 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:fkbp5_mouse(display_long)|uniprotkb:FK506-binding protein 5(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Fkbp5(gene name)|psi-mi:Fkbp5(display_short)|uniprotkb:Fkbp51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_034350.1|ensembl:ENSMUSG00000024222(gene)|ensembl:ENSMUST00000079413(transcript)|ensembl:ENSMUST00000114792(transcript)|ensembl:ENSMUST00000177939(transcript)|ensembl:ENSMUST00000233102(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031210|mint:Q64378|reactome:R-MMU-3371497|reactome:R-MMU-8939211 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ihh8rfBDWGjo3gceXNl406Y50pU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BH64 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1994334|uniprotkb:Q8BL28|ensembl:ENSMUSP00000096397 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ehd2_mouse(display_long)|uniprotkb:Ehd2(gene name)|psi-mi:Ehd2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:XP_011248884.1|refseq:NP_694708.2|dip:DIP-46806N|ensembl:ENSMUSG00000074364(gene)|ensembl:ENSMUST00000098799(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006897"(endocytosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029945|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|rcsb pdb:2QPT|rcsb pdb:4CID|reactome:R-MMU-983231 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Y6gH2n3nnVFeqaZE0T6T2gGqtyw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P54823 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-3647041|ensembl:ENSMUSP00000128421|ensembl:ENSMUSP00000149620|uniprotkb:O54979|uniprotkb:Q3UFI3|uniprotkb:Q8BW68 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ddx6_mouse(display_long)|uniprotkb:Ddx6(gene name)|psi-mi:Ddx6(display_short)|uniprotkb:Hlr2(gene name synonym)|uniprotkb:Rck(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:Oncogene RCK homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|mint:P54823|reactome:R-MMU-430039|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|ensembl:ENSMUSG00000032097(gene)|ensembl:ENSMUST00000170489(transcript)|ensembl:ENSMUST00000217034(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_001104296.1|refseq:NP_031867.1|refseq:NP_851841.2|refseq:XP_011240693.1|refseq:XP_011240694.1|refseq:XP_017168613.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Q80hxmsbz9kQgOP9Gflto87Sp/M10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BP48 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-3870579|ensembl:ENSMUSP00000029804 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:map11_mouse(display_long)|uniprotkb:Metap1(gene name)|psi-mi:Metap1(display_short)|uniprotkb:Peptidase M 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_780433.1|ensembl:ENSMUSG00000005813(gene)|ensembl:ENSMUST00000029804(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|interpro:IPR031615|interpro:IPR036005|mint:Q8BP48|reactome:R-MMU-2514859 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:gfQHRxpM/VdAT4JEKmIWEJ94c6M10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9QZD9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7466616|intact:MINT-1869798|ensembl:ENSMUSP00000099653 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3i_mouse(display_long)|uniprotkb:Eif3i(gene name)|psi-mi:Eif3i(display_short)|uniprotkb:Trip1(gene name synonym)|uniprotkb:Eif3s2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_061269.1|ensembl:ENSMUSG00000028798(gene)|ensembl:ENSMUST00000102593(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q9QZD9|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 - - function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:R7AzLvRTsjnmue48odsUwRAUIsM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q61249 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7002233|ensembl:ENSMUSP00000033570|intact:MINT-4597261 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:igbp1_mouse(display_long)|uniprotkb:Igbp1(gene name)|psi-mi:Igbp1(display_short)|uniprotkb:Pc52(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:Alpha4 phosphoprotein(gene name synonym)|uniprotkb:Lymphocyte signal transduction molecule alpha 4(gene name synonym)|uniprotkb:p52(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000031221(gene)|ensembl:ENSMUST00000033570(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042113"(B cell activation)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:Q61249|rcsb pdb:3QC1|refseq:NP_032810.4 - - comment:mint|comment:homomint|function:Associated to surface IgM-receptor; may be involved in signal transduction. May be involved in regulation of the catalytic activity of type 2A-related serine/threonine phosphatases figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ff6HGCQCC1YpTFCUPDMACHww2E010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:A2AWA9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8418832|uniprotkb:Q8R312|uniprotkb:Q8C8W3|uniprotkb:Q8CD74|uniprotkb:Q5DTN1|uniprotkb:Q8BQ32|intact:MINT-5095880|ensembl:ENSMUSP00000061624|ensembl:ENSMUSP00000108542 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rbgp1_mouse(display_long)|uniprotkb:Rabgap1(gene name)|psi-mi:Rabgap1(display_short)|uniprotkb:Kiaa4104(gene name synonym)|uniprotkb:Rab6 GTPase-activating protein GAPCenA(gene name synonym)|uniprotkb:GAP and centrosome-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_666233.2|refseq:NP_001029132.1|refseq:XP_006498057.1|refseq:XP_017172964.1|ensembl:ENSMUSG00000035437(gene)|ensembl:ENSMUST00000061179(transcript)|ensembl:ENSMUST00000112920(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022164|interpro:IPR033185|interpro:IPR035969|mint:A2AWA9|reactome:R-MMU-8854214 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:4wzsJeO0BAoMAsqYrdl87InNkzM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q3TCH7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8320699|uniprotkb:Q3THM3|uniprotkb:Q91Z44|intact:MINT-4122171|ensembl:ENSMUSP00000016680 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:cul4a_mouse(display_long)|uniprotkb:Cul4a(gene name)|psi-mi:Cul4a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_666319.2|ensembl:ENSMUSG00000031446(gene)|ensembl:ENSMUST00000016680(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q3TCH7|reactome:R-MMU-110314|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664 - - function:"Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. DCX(DET1-COP1) directs ubiquitination of JUN. DCX(DDB2) directs ubiquitination of XPC. In association with RBX1, DDB1 and DDB2 is required for histone H3 and histone H4 ubiquitination in response to ultraviolet and may be important for subsequent DNA repair. DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitiantion of TP53 in response to radiation-induced DNA damage and during DNA replication. In association with DDB1 and SKP2 probably is involved in ubiquitination of CDKN1B/p27kip. Is involved in ubiquitination of HOXA9"|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:nGMM2MrmponVO+86aankGqgUIVY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6A0A9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8327719|intact:MINT-1858841|uniprotkb:Q91Z16|uniprotkb:B3DFJ0|uniprotkb:A0PJK6|ensembl:ENSMUSP00000053877 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:f120a_mouse(display_long)|uniprotkb:Kiaa0183(gene name synonym)|uniprotkb:Ossa(gene name synonym)|uniprotkb:Oxidative stress-associated Src activator(gene name synonym)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001028440.2|ensembl:ENSMUSG00000038014(gene)|ensembl:ENSMUST00000060805(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q6A0A9 - - comment:"fragmentation type: fragment"|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:tZj0TOhfuvvF4GaEPHI7jWpKyl810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9WV54 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8400422|intact:MINT-4088419|ensembl:ENSMUSP00000034000 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:asah1_mouse(display_long)|uniprotkb:Asah1(gene name)|psi-mi:Asah1(display_short)|uniprotkb:Asah(gene name synonym)|uniprotkb:Acylsphingosine deacylase(gene name synonym)|uniprotkb:N-acylsphingosine amidohydrolase(gene name synonym)|uniprotkb:N-acylethanolamine hydrolase ASAH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_062708.1|refseq:XP_017168016.1|refseq:XP_017168017.1|refseq:XP_017168018.1|refseq:XP_017168019.1|refseq:XP_017168020.1|refseq:XP_017168021.1|ensembl:ENSMUSG00000031591(gene)|ensembl:ENSMUST00000034000(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017040"(N-acylsphingosine amidohydrolase activity)|go:"GO:0017064"(fatty acid amide hydrolase activity)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046514"(ceramide catabolic process)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0062098"(regulation of programmed necrotic cell death)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0102121"(ceramidase activity)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR016699(Acid ceramidase-like)|interpro:IPR029130|interpro:IPR029132|mint:Q9WV54|reactome:R-MMU-1660662|reactome:R-MMU-6798695 - - comment:mint|function:Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:BGzmEP8nXDEYxUKI09Bxxi8yXyA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6P7W2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7713890|ensembl:ENSMUSP00000003857|uniprotkb:Q9ES31|intact:MINT-1893516|uniprotkb:Q3TUN8 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:shkb1_mouse(display_long)|uniprotkb:Shkbp1(gene name)|psi-mi:Shkbp1(display_short)|uniprotkb:Sb1(gene name synonym)|uniprotkb:SETA-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000089832(gene)|ensembl:ENSMUST00000003857(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q6P7W2|reactome:R-MMU-9013148|refseq:NP_619617.2 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:pREcReRnt1Xn0/F0TFgKj/SK3Lg10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q08879 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8394126|uniprotkb:Q91ZC9|uniprotkb:Q08878|intact:MINT-245863|uniprotkb:Q8C3B1|uniprotkb:Q922K8|ensembl:ENSMUSP00000054583 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:fbln1_mouse(display_long)|uniprotkb:Fbln1(gene name)|psi-mi:Fbln1(display_short)|uniprotkb:Basement-membrane protein 90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_034310.2|refseq:NP_001334017.1|ensembl:ENSMUSG00000006369(gene)|ensembl:ENSMUST00000057410(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0071953"(elastic fiber)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904188"(negative regulation of transformation of host cell by virus)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017048(Fibulin-1)|interpro:IPR018097|interpro:IPR026823|mint:Q08879|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site) - - comment:mint|function:"Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:wsHVgwYdck7EFaz0SUX1lQgrgOU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8C5R8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8334614|intact:MINT-4114466|ensembl:ENSMUSP00000133931 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:q8c5r8_mouse(display_long)|uniprotkb:Prps1l1(gene name)|psi-mi:Prps1l1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_083570.1|ensembl:ENSMUSG00000092305(gene)|ensembl:ENSMUST00000134550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0008584"(male gonad development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|mint:Q8C5R8 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:eOLJeiWr9SSRHiyhjjcrJSamnjA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VEH3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8313699|ensembl:ENSMUSP00000027684|uniprotkb:Q9CTB0|intact:MINT-4120060|uniprotkb:Q99KS1 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:arl8a_mouse(display_long)|uniprotkb:Arl8a(gene name)|psi-mi:Arl8a(display_short)|uniprotkb:Arl10b(gene name synonym)|uniprotkb:Gie2(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 10B(gene name synonym)|uniprotkb:Novel small G protein indispensable for equal chromosome segregation 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000026426(gene)|ensembl:ENSMUST00000027684(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0045202"(synapse)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044154|mint:Q8VEH3|reactome:R-MMU-6798695|refseq:NP_081099.1 - - function:May play a role in lysosomes motility. Alternatively, may play a role in chromosomes segregation|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:8+7GJ2m7t5/hsw0XdfgZmxYV+bs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P25976 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7364139|intact:MINT-4084181 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ubf1_mouse(display_long)|uniprotkb:Ubtf(gene name)|psi-mi:Ubtf(display_short)|uniprotkb:Tcfubf(gene name synonym)|uniprotkb:Ubf1(gene name synonym)|uniprotkb:Ubf-1(gene name synonym)|uniprotkb:Upstream-binding factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 mint:P25976|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001165"(RNA polymerase I cis-regulatory region sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR029215|interpro:IPR036910|rcsb pdb:1V63|rcsb pdb:1V64|rcsb pdb:1WGF|reactome:R-MMU-73728|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|dip:DIP-29977N - - comment:mint|function:UBF recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor SL1. It binds specifically to the upstream control element figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:TJRBUUHHZDYhIRdbtsijzuOSbAo10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CWL8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8338374|uniprotkb:Q8VHE3|intact:MINT-4092455|uniprotkb:Q3UL41|uniprotkb:Q80X64|ensembl:ENSMUSP00000029178 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ctbl1_mouse(display_long)|uniprotkb:Ctnnbl1(gene name)|psi-mi:Ctnnbl1(display_short)|uniprotkb:Nuclear-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_079956.3|ensembl:ENSMUSG00000027649(gene)|ensembl:ENSMUST00000029178(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0019899"(enzyme binding)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013180(Protein of unknown function DUF1716, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039678|mint:Q9CWL8|reactome:R-MMU-72163 - - function:Induces apoptosis in CHO cells|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:RnoDTJHBaLzvuDxK1rtk6c3mFNM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P83510 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7280013|intact:MINT-4138101|ensembl:ENSMUSP00000124681 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tnik_mouse(display_long)|uniprotkb:Tnik(gene name)|psi-mi:Tnik(display_short)|uniprotkb:Kiaa0551(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001156480.1|ensembl:ENSMUSG00000027692(gene)|ensembl:ENSMUST00000159236(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007256"(obsolete activation of JNKK activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P83510|reactome:R-MMU-2559580|go:"GO:0055037"(recycling endosome)|dip:DIP-57467N - - comment:mint|function:Stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in cytoskeletal regulation figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:+Hdc1nFS32RS9/n1kdeF66gw2zs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9ERA6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8338752|intact:MINT-4137591|uniprotkb:Q8VD06|ensembl:ENSMUSP00000031288 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tfp11_mouse(display_long)|uniprotkb:Tfip11(gene name)|psi-mi:Tfip11(display_short)|uniprotkb:Tip39(gene name synonym)|uniprotkb:Stip(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)|uniprotkb:Tuftelin-interacting protein 39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_061253.2|ensembl:ENSMUSG00000029345(gene)|ensembl:ENSMUST00000031288(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9ERA6|reactome:R-MMU-72163 - - comment:mint|function:May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix. May also be involved in pre-mRNA splicing figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:p51lkjhae2QI5PvI1yAO42Y1uI010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q02614 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8458227|intact:MINT-4119830|uniprotkb:Q8VDJ5|ensembl:ENSMUSP00000114844 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:s30bp_mouse(display_long)|uniprotkb:Sap30bp(gene name)|psi-mi:Sap30bp(display_short)|uniprotkb:Hcngp(gene name synonym)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_065229.2|ensembl:ENSMUSG00000020755(gene)|ensembl:ENSMUST00000140991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q02614 - - comment:mint|function:"Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival (By similarity). May be involved in the regulation of beta-2-microglobulin genes" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:WI5iNVKs+YvBfV1rwLaMcUwddEs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O54865 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8312524|ensembl:ENSMUSP00000029635|intact:MINT-4105057 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:gcyb1_mouse(display_long)|uniprotkb:Gucy1b1(gene name)|psi-mi:Gucy1b1(display_short)|uniprotkb:Guanylate cyclase soluble subunit beta-3(gene name synonym)|uniprotkb:Gucy1b3(gene name synonym)|uniprotkb:Soluble guanylate cyclase small subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000028005(gene)|ensembl:ENSMUST00000029635(transcript)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0004383"(guanylate cyclase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006182"(cGMP biosynthetic process)|go:"GO:0008074"(guanylate cyclase complex, soluble)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0020037"(heme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043167"(ion binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047805"(cytidylate cyclase activity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099555"(trans-synaptic signaling by nitric oxide, modulating synaptic transmission)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR011644(Haem NO binding)|interpro:IPR011645(Haem NO binding associated)|interpro:IPR018297|interpro:IPR024096|interpro:IPR029787|interpro:IPR038158|go:"GO:0038060"(nitric oxide-cGMP-mediated signaling pathway)|interpro:IPR042463|mint:O54865|refseq:NP_059497.1 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:3pc+RzhGlK9BC07aLmSxY1tDjT410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P52430 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8383843|uniprotkb:Q91X30|intact:MINT-4121591|intact:MINT-1863898|ensembl:ENSMUSP00000002663 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pon1_mouse(display_long)|uniprotkb:Pon1(gene name)|psi-mi:Pon1(display_short)|uniprotkb:Pon(gene name synonym)|uniprotkb:Serum aryldialkylphosphatase 1(gene name synonym)|uniprotkb:Aromatic esterase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035264.2|ensembl:ENSMUSG00000002588(gene)|ensembl:ENSMUST00000002663(transcript)|go:"GO:0004063"(aryldialkylphosphatase activity)|go:"GO:0004064"(arylesterase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0008015"(blood circulation)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046395"(carboxylic acid catabolic process)|go:"GO:0046434"(organophosphate catabolic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0102007"(acyl-L-homoserine-lactone lactonohydrolase activity)|go:"GO:1902617"(response to fluoride)|interpro:IPR002640(Arylesterase)|interpro:IPR008363(Paraoxonase1)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|mint:P52430|reactome:R-MMU-2142688 - - function:Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:jOf9eLE5gkwqW/5pqIMax3fmXO810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62315 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7229109|uniprotkb:Q3UYM0|uniprotkb:P13641|intact:MINT-124808|ensembl:ENSMUSP00000002551 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:smd1_mouse(display_long)|uniprotkb:Snrpd1(gene name)|psi-mi:Snrpd1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033252.1|ensembl:ENSMUSG00000002477(gene)|ensembl:ENSMUST00000002551(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034102|mint:P62315|reactome:R-MMU-191859|reactome:R-MMU-72163|reactome:R-MMU-72165 - - function:May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:bfXwsV+IOjDPCoOJOoMQgECyiII10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8N7N5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8392331|uniprotkb:Q8CII7|intact:MINT-4118058|uniprotkb:Q8CIK6|ensembl:ENSMUSP00000073778|ensembl:ENSMUSP00000141731|ensembl:ENSMUSP00000141732 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dcaf8_mouse(display_long)|uniprotkb:D1Ucla4(gene name synonym)|uniprotkb:H326(gene name synonym)|uniprotkb:Dcaf8(gene name)|psi-mi:Dcaf8(display_short)|uniprotkb:Wdr42a(gene name synonym)|uniprotkb:WD repeat-containing protein 42A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:XP_011237191.1|refseq:NP_705783.1|refseq:XP_006497128.1|ensembl:ENSMUSG00000026554(gene)|ensembl:ENSMUST00000074144(transcript)|ensembl:ENSMUST00000191689(transcript)|ensembl:ENSMUST00000192704(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q8N7N5|reactome:R-MMU-8951664 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6bs5FOYz3K84ojybQs6HGQQ+zqA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BIF9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8387101|uniprotkb:B9EHE2|intact:MINT-4110750|ensembl:ENSMUSP00000092468 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:zn787_mouse(display_long)|uniprotkb:Znf787(gene name)|psi-mi:Znf787(display_short)|uniprotkb:Zfp787(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001013030.1|refseq:XP_006540376.1|ensembl:ENSMUSG00000046792(gene)|ensembl:ENSMUST00000094870(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8BIF9 - - function:May be involved in transcriptional regulation|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:iSKCf1BsXS/iHQK+Dl5xGpzOPyA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q7TNG5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8317948|uniprotkb:Q9DAS8|intact:MINT-5085024|ensembl:ENSMUSP00000112447 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:emal2_mouse(display_long)|uniprotkb:Eml2(gene name)|psi-mi:Eml2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001156468.1|refseq:NP_082429.1|ensembl:ENSMUSG00000040811(gene)|ensembl:ENSMUST00000120595(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010968"(regulation of microtubule nucleation)|go:"GO:0015631"(tubulin binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR001680(WD40 repeat)|interpro:IPR005108(HELP)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR033016|mint:Q7TNG5 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:7/HcWLeFFlBXBDoxH/z9/Fv538o10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q920Q6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8316064|ensembl:ENSMUSP00000090470|intact:MINT-4102465|uniprotkb:Q920Q7|uniprotkb:Q8BQ90 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:msi2h_mouse(display_long)|uniprotkb:Msi2(gene name)|psi-mi:Msi2(display_short)|uniprotkb:Msi2h(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000069769(gene)|ensembl:ENSMUST00000092794(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048864"(stem cell development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034126|interpro:IPR034130|interpro:IPR035979|mint:Q920Q6|reactome:R-MMU-9013418|refseq:NP_473384.1|refseq:XP_006534505.1 - - comment:mint|function:RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:TcmTrRzmn33cxlF12WfnK//swMI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O55201 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8321883|intact:MINT-4105191|uniprotkb:Q3UJH1|uniprotkb:Q3UJ77|uniprotkb:Q3UKD7|uniprotkb:Q6PFR4|uniprotkb:Q6PB73|uniprotkb:Q6PDP0|uniprotkb:Q3UM54|ensembl:ENSMUSP00000003527|ensembl:ENSMUSP00000147164 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:spt5h_mouse(display_long)|uniprotkb:Supt5h(gene name)|psi-mi:Supt5h(display_short)|uniprotkb:Supt5(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_038704.1|ensembl:ENSMUSG00000003435(gene)|ensembl:ENSMUST00000003527(transcript)|ensembl:ENSMUST00000209141(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O55201|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-75955|reactome:R-MMU-77075 - - comment:mint|function:"Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:YOFTk5cUKQNJ/ApjpLqduHjivOI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D1H9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8357724|uniprotkb:Q5NCN1|intact:MINT-4126576|ensembl:ENSMUSP00000070848 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:mfap4_mouse(display_long)|uniprotkb:Mfap4(gene name)|psi-mi:Mfap4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001334474.1|refseq:NP_083844.1|ensembl:ENSMUSG00000042436(gene)|ensembl:ENSMUST00000064783(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0009650"(UV protection)|go:"GO:0010712"(regulation of collagen metabolic process)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0071953"(elastic fiber)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:0097435"(supramolecular fiber organization)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR036056|mint:Q9D1H9|reactome:R-MMU-2129379 - - function:Could be involved in calcium-dependent cell adhesion or intercellular interactions|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:2IxrCfLtF0OwHgd0FZvIgahCaIU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9R0U0 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8338686|uniprotkb:O70307|intact:MINT-4095399|uniprotkb:B1AV44|uniprotkb:O88468|uniprotkb:Q3TGW7|uniprotkb:B1AV45|uniprotkb:Q8CFZ1|uniprotkb:Q9R0T9|ensembl:ENSMUSP00000101479 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srs10_mouse(display_long)|uniprotkb:Srsf10(gene name)|psi-mi:Srsf10(display_short)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:Fusip1(gene name synonym)|uniprotkb:Neural-salient serine/arginine-rich protein(gene name synonym)|uniprotkb:Neural-specific SR protein(gene name synonym)|uniprotkb:Nssr(gene name synonym)|uniprotkb:Sfrs13a(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym)|uniprotkb:Srsf13a(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001271124.1|refseq:NP_001271125.1|refseq:NP_034308.1|refseq:NP_001073856.1|ensembl:ENSMUSG00000028676(gene)|ensembl:ENSMUST00000105853(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:Q9R0U0|reactome:R-MMU-72163 - - comment:mint|function:"Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRP70. Required for splicing repression in M-phase cells and after heat shock (By similarity). May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:abrRZLYWl3wlG2rHzVZMgej5EWk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q05117 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8381271|intact:MINT-1851665|ensembl:ENSMUSP00000065425|ensembl:ENSMUSP00000110970|ensembl:ENSMUSP00000127128|ensembl:ENSMUSP00000149597|ensembl:ENSMUSP00000150903 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ppa5_mouse(display_long)|uniprotkb:Acp5(gene name)|psi-mi:Acp5(display_short)|uniprotkb:T5ap(gene name synonym)|uniprotkb:Trap(gene name synonym)|uniprotkb:Tartrate-resistant acid ATPase(gene name synonym)|uniprotkb:Type 5 acid phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:XP_011240686.1|refseq:NP_031414.1|refseq:NP_001095874.1|refseq:NP_001095875.1|refseq:XP_006510007.1|refseq:XP_006510008.1|refseq:XP_006510009.1|ensembl:ENSMUSG00000001348(gene)|ensembl:ENSMUST00000069330(transcript)|ensembl:ENSMUST00000115315(transcript)|ensembl:ENSMUST00000165735(transcript)|ensembl:ENSMUST00000213815(transcript)|ensembl:ENSMUST00000217643(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0005764"(lysosome)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0034097"(response to cytokine)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060349"(bone morphogenesis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR024927|interpro:IPR029052|mint:Q05117|reactome:R-MMU-196843 - - comment:mint|function:May play a role in the process of bone resorption. The osteoclastic trap acts on nucleotide tri- and diphosphates with higher affinity, compared with other substrates figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:SJiFaGcrjWUU+z4TD2VupvEPfJ410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9Z1K5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8312579|ensembl:ENSMUSP00000126531|uniprotkb:Q8CFJ4|uniprotkb:Q6PF92|intact:MINT-4088309|uniprotkb:E9Q1X3 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ari1_mouse(display_long)|uniprotkb:Arih1(gene name)|psi-mi:Arih1(display_short)|uniprotkb:Ari(gene name synonym)|uniprotkb:Ubch7bp(gene name synonym)|uniprotkb:Uip77(gene name synonym)|uniprotkb:Protein ariadne-1 homolog(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-binding protein 1(gene name synonym)|uniprotkb:UbcH7-binding protein(gene name synonym)|uniprotkb:UbcM4-interacting protein 77(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ARIH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:Q9Z1K5|reactome:R-MMU-1169408|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSMUSG00000025234(gene)|ensembl:ENSMUST00000171975(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097413"(Lewy body)|refseq:NP_064311.2 - - comment:mint|function:Might act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ZYzYvLjbsUa6q1rOTaHWJatXliI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P54731 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8663987|ensembl:ENSMUSP00000099785|intact:MINT-1513304|uniprotkb:Q6P1F8 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:faf1_mouse(display_long)|uniprotkb:Faf1(gene name)|psi-mi:Faf1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000010517(gene)|ensembl:ENSMUST00000102724(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008219"(cell death)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR033043|interpro:IPR036249|interpro:IPR044541|refseq:NP_032009.2 - - comment:mint|function:Potentiates but cannot initiate FAS-induced apoptosis figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:wqnTbKeoS+2ORpxUY5LImiuC5W010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D0B0 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8459497|uniprotkb:Q9CRN3|intact:MINT-4126379|ensembl:ENSMUSP00000031513 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srsf9_mouse(display_long)|uniprotkb:Srsf9(gene name)|psi-mi:Srsf9(display_short)|uniprotkb:Sfrs9(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_079849.1|ensembl:ENSMUSG00000029538(gene)|ensembl:ENSMUST00000031513(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034503|interpro:IPR034995|interpro:IPR035979|mint:Q9D0B0|rcsb pdb:1WG4|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856 - - function:Plays a role in constitutive splicing and can modulate the selection of alternative splice sites|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:25t44o/3FTGaNAXdHibw1ibYdUc10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P24788 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8341078|intact:MINT-4090174|uniprotkb:Q7TST4|uniprotkb:Q8BP53|uniprotkb:Q61399|uniprotkb:Q3UI03|ensembl:ENSMUSP00000070527|ensembl:ENSMUSP00000101225 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:cd11b_mouse(display_long)|uniprotkb:Cdk11b(gene name)|psi-mi:Cdk11b(display_short)|uniprotkb:Cdc2l1(gene name synonym)|uniprotkb:Cdk11(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 1(gene name synonym)|uniprotkb:Cell division protein kinase 11(gene name synonym)|uniprotkb:Cyclin-dependent kinase 11(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001334237.1|refseq:XP_011248481.1|refseq:NP_031687.2|refseq:XP_017175418.1|refseq:XP_017175419.1|refseq:XP_006538571.1|refseq:XP_006538574.1|refseq:XP_017175422.1|refseq:XP_017175423.1|ensembl:ENSMUSG00000029062(gene)|ensembl:ENSMUST00000067081(transcript)|ensembl:ENSMUST00000105600(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P24788|reactome:R-MMU-380270 - - comment:mint|function:Acts as a negative regulator of the normal cell cycle progression. In vitro, this protein kinase has been shown to phosphorylate a number of substrates, including histone h1, casein, and galactosyltransferase. May function in regulating proliferation by the phosphorylation and subsequent plasma membrane targeting of galactosyltransferase figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ZSpex1pgx216ZntR9dgjyX85zFQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VE97 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8340598|uniprotkb:Q9JJC3|intact:MINT-4134372 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srsf4_mouse(display_long)|uniprotkb:Srsf4(gene name)|psi-mi:Srsf4(display_short)|uniprotkb:Sfrs4(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 4(gene name synonym)|uniprotkb:MNCb-2616(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR035585|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q8VE97|interpro:IPR035979|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|interpro:IPR000504(RNA recognition motif, RNP-1) - - comment:mint|function:A probable role in alternative splice site selection during pre-mRNA splicing figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:0ZmqFkGQj7wji2l3o1xa5CEbp/410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9DBZ5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7466644|uniprotkb:Q8K3A1|uniprotkb:Q58EU9|intact:MINT-4098437|ensembl:ENSMUSP00000066038 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3k_mouse(display_long)|uniprotkb:Eif3k(gene name)|psi-mi:Eif3k(display_short)|uniprotkb:Eif3s12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001272871.1|refseq:NP_082935.1|ensembl:ENSMUSG00000053565(gene)|ensembl:ENSMUST00000066070(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9DBZ5|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 - - function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6inN9+78GHgwKiXC/s5lDjTbKsw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CX97 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8459001|uniprotkb:A2RS10|intact:MINT-4125732|ensembl:ENSMUSP00000039010 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:wdr55_mouse(display_long)|uniprotkb:Wdr55(gene name)|psi-mi:Wdr55(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_080740.2|ensembl:ENSMUSG00000042660(gene)|ensembl:ENSMUST00000049323(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017422(WD repeat protein 55)|interpro:IPR019775|interpro:IPR024977|interpro:IPR036322|mint:Q9CX97 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:vvo19drasx/Cwhjq7r+A8TKO+1w10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q3UMU9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7627961|intact:MINT-8300358|uniprotkb:Q99L92|uniprotkb:Q3UIH6|uniprotkb:D6CHX5|intact:UNK-5536871|uniprotkb:O35540|intact:MINT-4104792|ensembl:ENSMUSP00000152948 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hdgr2_mouse(display_long)|uniprotkb:Hdgfl2(gene name)|psi-mi:Hdgfl2(display_short)|uniprotkb:Hdgfrp2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001317982.1|refseq:NP_001291713.1|refseq:NP_001291714.1|refseq:NP_032259.1|ensembl:ENSMUSG00000002833(gene)|ensembl:ENSMUST00000226053(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030307"(positive regulation of cell growth)|interpro:IPR000313(PWWP)|interpro:IPR021567|interpro:IPR035441|interpro:IPR035496|interpro:IPR036218|mint:Q3UMU9 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:p7C/kgoFDDAsp0NllmASyHV8DYw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8C1D8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8387298|uniprotkb:Q3UWB0|uniprotkb:Q8BY73|uniprotkb:Q6NVD1|uniprotkb:Q9D9H4|intact:MINT-4114051|uniprotkb:Q3TQ25|ensembl:ENSMUSP00000025243 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:iws1_mouse(display_long)|uniprotkb:Iws1(gene name)|psi-mi:Iws1(display_short)|uniprotkb:Iws1l(gene name synonym)|uniprotkb:IWS1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_775617.1|ensembl:ENSMUSG00000024384(gene)|ensembl:ENSMUST00000025243(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0090239"(regulation of histone H4 acetylation)|go:"GO:2001253"(regulation of histone H3-K36 trimethylation)|interpro:IPR017923|interpro:IPR035441|mint:Q8C1D8|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:r9aQ40EqQpf32tyzOSEBZYOT4CY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P97822 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8357774|uniprotkb:Q8BPF8|uniprotkb:Q3TH89|uniprotkb:Q9CZD2|uniprotkb:Q8C7Q8|uniprotkb:Q8C2L4|intact:MINT-4087684|intact:EBI-17172721|uniprotkb:E9Q5H9|uniprotkb:Q3TX26|ensembl:ENSMUSP00000128483 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:an32e_mouse(display_long)|uniprotkb:Anp32e(gene name)|psi-mi:Anp32e(display_short)|uniprotkb:Cpd1(gene name synonym)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:Cerebellar postnatal development protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001240687.1|refseq:NP_001240686.1|refseq:NP_075699.3|ensembl:ENSMUSG00000015749(gene)|ensembl:ENSMUST00000165307(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043486"(histone exchange)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P97822 - - function:"Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity"|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:KMIegWYJxkmzPWUNdDHwxRm+A1Y10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O54984 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8316929|uniprotkb:Q3TAQ4|intact:MINT-4088407|ensembl:ENSMUSP00000065337 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:get3_mouse(display_long)|uniprotkb:Get3(gene name)|psi-mi:Get3(display_short)|uniprotkb:Arsa(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Asna1(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_062626.1|ensembl:ENSMUSG00000052456(gene)|ensembl:ENSMUST00000064314(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O54984 - - comment:mint|function:Anion-transporting ATPase. Catalyzes the extrusion of arsenite figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:D9pDUhGLHmu5RhWaee3xfk3GKE410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62305 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8340154|uniprotkb:Q15498|intact:MINT-1853918|uniprotkb:P08578|ensembl:ENSMUSP00000128400 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ruxe_mouse(display_long)|uniprotkb:Snrpe(gene name)|psi-mi:Snrpe(display_short)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033253.1|ensembl:ENSMUSG00000090553(gene)|ensembl:ENSMUST00000166915(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62305|reactome:R-MMU-111367|reactome:R-MMU-191859|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-73856|reactome:R-MMU-77588|interpro:IPR001163(Like-Sm ribonucleoprotein, core) - - function:Associated with snRNP U1, U2, U4/U6 and U5|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62996 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8320461|uniprotkb:O15449|uniprotkb:Q64283|intact:MINT-4138402|uniprotkb:Q15815|ensembl:ENSMUSP00000124846 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tra2b_mouse(display_long)|uniprotkb:Silg41(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym)|uniprotkb:Silica-induced gene 41 protein(gene name synonym)|uniprotkb:Tra2b(gene name)|psi-mi:Tra2b(display_short)|uniprotkb:Sfrs10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033212.1|refseq:NP_001317483.1|refseq:NP_001317484.1|ensembl:ENSMUSG00000022858(gene)|ensembl:ENSMUST00000161286(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P62996|reactome:R-MMU-72163|reactome:R-MMU-9013418|reactome:R-MMU-9013422 - - comment:mint|function:Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8C0E2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8314940|ensembl:ENSMUSP00000034470|uniprotkb:Q8K2V3|uniprotkb:Q3TN45|intact:MINT-3253852 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vp26b_mouse(display_long)|uniprotkb:Vps26b(gene name)|psi-mi:Vps26b(display_short)|uniprotkb:Vesicle protein sorting 26B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000031988(gene)|ensembl:ENSMUST00000034470(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:Q8C0E2|rcsb pdb:2R51|rcsb pdb:3LH8|rcsb pdb:3LH9|rcsb pdb:3LHA|refseq:NP_821170.1 - - comment:mint|function:"Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:0ldtjq7g6fEiaFTAusA8J+Xy4Qg10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BHA3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8346856|intact:MINT-4127045|uniprotkb:Q9D4Q5|uniprotkb:Q9D363|ensembl:ENSMUSP00000021339 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dtd2_mouse(display_long)|uniprotkb:Dtd2(gene name)|psi-mi:Dtd2(display_short)|uniprotkb:Animalia-specific tRNA deacylase(gene name synonym)|uniprotkb:D-tyrosyl-tRNA deacylase 2(gene name synonym)|uniprotkb:L-alanyl-tRNA deacylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001334333.1|refseq:NP_083821.1|ensembl:ENSMUSG00000020956(gene)|ensembl:ENSMUST00000021339(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006399"(tRNA metabolic process)|go:"GO:0051500"("D-tyrosyl-tRNA(Tyr) deacylase activity")|go:"GO:0106074"(aminoacyl-tRNA metabolism involved in translational fidelity)|go:"GO:0106105"("Ala-tRNA(Thr) hydrolase activity")|interpro:IPR003732("D-tyrosyl-tRNA(Tyr) deacylase")|interpro:IPR023509|mint:Q8BHA3|rcsb pdb:5XAQ - - comment:mint|function:"Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:SUJwEE0jTeYS9G6Xae7UkzRQ+uA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9QZ88 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome) - - function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VE09 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8365622|intact:MINT-4390945|uniprotkb:Q9CYV6 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tt39c_mouse(display_long)|uniprotkb:Ttc39c(gene name)|psi-mi:Ttc39c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_082617.2|interpro:IPR019412|mint:Q8VE09|go:"GO:0032474"(otolith morphogenesis)|go:"GO:0060271"(cilium assembly) - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:PkuhPjB0mc5z/Sl+y98wdJhSi1s10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O08848 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8322484|intact:MINT-4132821|uniprotkb:Q9QYD8|ensembl:ENSMUSP00000125623 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ro60_mouse(display_long)|uniprotkb:RO60(gene name)|psi-mi:RO60(display_short)|uniprotkb:Ssa2(gene name synonym)|uniprotkb:TROVE domain family member 2(gene name synonym)|uniprotkb:Trove2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_038863.1|refseq:XP_017174940.1|ensembl:ENSMUSG00000018199(gene)|ensembl:ENSMUST00000159879(transcript)|go:"GO:0002520"(immune system development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0009411"(response to UV)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0034336"(misfolded RNA binding)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR008858(TROVE)|interpro:IPR036465|interpro:IPR037214|interpro:IPR040322|mint:O08848 - - comment:mint|function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:aWkAAnWO4Q8288vrhtKGEh3/ZcY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9Z204 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8339380|uniprotkb:Q3TLB5|intact:MINT-1864181|uniprotkb:Q501Q3|uniprotkb:Q8C2G5|uniprotkb:Q9CY83|uniprotkb:Q9CQT3|uniprotkb:Q99KE2|ensembl:ENSMUSP00000107237|ensembl:ENSMUSP00000133052 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hnrpc_mouse(display_long)|uniprotkb:Hnrnpc(gene name)|psi-mi:Hnrnpc(display_short)|uniprotkb:Hnrpc(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001164453.1|refseq:NP_001164455.1|refseq:NP_058580.1|refseq:NP_001164454.1|refseq:NP_001164452.1|refseq:XP_006518634.1|refseq:XP_006518635.1|refseq:XP_006518637.1|refseq:XP_006518641.1|refseq:XP_006518644.1|refseq:XP_017171338.1|refseq:XP_017171339.1|refseq:XP_017171340.1|refseq:XP_017171344.1|refseq:XP_017171345.1|refseq:XP_017171346.1|refseq:XP_017171347.1|refseq:XP_017171348.1|dip:DIP-59747N|ensembl:ENSMUSG00000060373(gene)|ensembl:ENSMUST00000111610(transcript)|ensembl:ENSMUST00000164655(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045120"(pronucleus)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090367"(negative regulation of mRNA modification)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990826"(nucleoplasmic periphery of the nuclear pore complex)|go:"GO:1990827"(deaminase binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:Q9Z204|reactome:R-MMU-4570464|reactome:R-MMU-72163|reactome:R-MMU-72203|reactome:R-MMU-9013418|reactome:R-MMU-9013422 - - comment:mint|function:Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:HJSd0uE4v3/gPiN//x5YLfpskKM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q91WK2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7466721|intact:MINT-4098428|ensembl:ENSMUSP00000022925 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3h_mouse(display_long)|uniprotkb:Eif3h(gene name)|psi-mi:Eif3h(display_short)|uniprotkb:Eif3s3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_542366.1|ensembl:ENSMUSG00000022312(gene)|ensembl:ENSMUST00000022925(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:Q91WK2|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 - - comment:mint|function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. Associates with the p170 subunit of EIF3 figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:mKyE784VSiEMqBaCyG2Vt9FhynM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P29788 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8354207|uniprotkb:Q8VII4|intact:MINT-4121605|uniprotkb:Q5SYG4|uniprotkb:Q91X32|intact:MINT-1522239|uniprotkb:Q9D080|ensembl:ENSMUSP00000017488 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vtnc_mouse(display_long)|uniprotkb:Vtn(gene name)|psi-mi:Vtn(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:S-protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035837.1|ensembl:ENSMUSG00000017344(gene)|ensembl:ENSMUST00000017488(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006955"(immune response)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097421"(liver regeneration)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P29788|reactome:R-MMU-2129379|reactome:R-MMU-216083|reactome:R-MMU-3000170|reactome:R-MMU-3000178|reactome:R-MMU-977606 - - function:Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:rxXmLGr5Ww3egoJqUmxAAEKSWVM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q00PI9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8586171|ensembl:ENSMUSP00000094515|uniprotkb:F8VPM4|intact:UNK-5385063 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hnrl2_mouse(display_long)|uniprotkb:Manp(gene name synonym)|uniprotkb:Hnrpul2(gene name synonym)|uniprotkb:MLF1-associated nuclear protein(gene name synonym)|uniprotkb:Hnrnpul2(gene name)|psi-mi:Hnrnpul2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000071659(gene)|ensembl:ENSMUST00000096753(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|refseq:NP_001074665.1 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:oPTke2/M1XC8ou8Lcc4UY4Qz8sw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VDM6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8322348|uniprotkb:Q3U201|uniprotkb:Q3UPB0|uniprotkb:Q8K365|uniprotkb:Q8BY45|intact:MINT-4119866|uniprotkb:Q6AZA7|ensembl:ENSMUSP00000146263 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hnrl1_mouse(display_long)|uniprotkb:Hnrnpul1(gene name)|psi-mi:Hnrnpul1(display_short)|uniprotkb:Hnrpul1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_659171.1|refseq:NP_835190.1|refseq:XP_006539918.1|refseq:XP_006539919.1|ensembl:ENSMUSG00000040725(gene)|ensembl:ENSMUST00000206832(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q8VDM6|reactome:R-MMU-72163 - - comment:mint|function:"Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:byU8hqFDp+qxXKbkevj3IJ0LpWQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8K4G1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8394098|uniprotkb:Q8K4G0|intact:MINT-4100656|uniprotkb:E9QPD9|ensembl:ENSMUSP00000037536 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ltbp4_mouse(display_long)|uniprotkb:Ltbp4(gene name)|psi-mi:Ltbp4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001107021.1|refseq:NP_783572.2|ensembl:ENSMUSG00000040488(gene)|ensembl:ENSMUST00000038618(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0046879"(hormone secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|mint:Q8K4G1|reactome:R-MMU-2129379 - - comment:mint|function:"May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM)" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:/dbUhp21QnBm+vJolZ3VEj8nkU410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q60960 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8573008|ensembl:ENSMUSP00000004054|uniprotkb:Q3TF32|intact:MINT-4597096 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ima5_mouse(display_long)|uniprotkb:Kpna1(gene name)|psi-mi:Kpna1(display_short)|uniprotkb:Rch2(gene name synonym)|uniprotkb:Importin alpha-S1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:XP_006521877.1|ensembl:ENSMUSG00000022905(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|ensembl:ENSMUST00000004054(transcript)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|reactome:R-MMU-140342|reactome:R-MMU-909733|refseq:NP_032491.2|dip:DIP-48614N - - comment:mint|function:"Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:V2skjc1VDIOFauddcuTX4cR01ek10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8QZY1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7770074|ensembl:ENSMUSP00000038839|intact:MINT-249281|uniprotkb:Q3THF8|uniprotkb:Q91YE4|uniprotkb:Q3TJ04 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3l_mouse(display_long)|uniprotkb:Eif3l(gene name)|psi-mi:Eif3l(display_short)|uniprotkb:Eif3eip(gene name synonym)|uniprotkb:Eif3s6ip(gene name synonym)|uniprotkb:Paf67(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit E-interacting protein(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6-interacting protein(gene name synonym)|uniprotkb:67 kDa polymerase-associated factor(gene name synonym)|uniprotkb:PAF67(gene name synonym)|uniprotkb:66 kDa tyrosine-rich heat shock protein(gene name synonym)|uniprotkb:HSP-66Y(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000033047(gene)|ensembl:ENSMUST00000040518(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019382|mint:Q8QZY1|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|refseq:NP_660121.2 - - comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:EFn/tQ3iRCMEDBdNQ71CDhC8nQ010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q921I9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8357473|intact:MINT-4094786|ensembl:ENSMUSP00000050940 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:exos4_mouse(display_long)|uniprotkb:Exosc4(gene name)|psi-mi:Exosc4(display_short)|uniprotkb:Rrp41(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_780608.1|ensembl:ENSMUSG00000034259(gene)|ensembl:ENSMUST00000059045(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q921I9|reactome:R-MMU-429958|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226 - - function:"Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity"|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Lw4r2cg7uP8F3oCLwlVKo6u7ZY410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CQ49 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8586642|ensembl:ENSMUSP00000023460|uniprotkb:Q3UI86|intact:MINT-4613350|uniprotkb:Q0VF93 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ncbp2_mouse(display_long)|uniprotkb:Ncbp2(gene name)|psi-mi:Ncbp2(display_short)|uniprotkb:Cbp20(gene name synonym)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR027157|interpro:IPR034148|interpro:IPR035979|reactome:R-MMU-111367|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-674695|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72187|reactome:R-MMU-72203|reactome:R-MMU-73856|reactome:R-MMU-77588|reactome:R-MMU-77595|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0034518"(RNA cap binding complex)|ensembl:ENSMUSG00000022774(gene)|ensembl:ENSMUST00000023460(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|refseq:NP_080830.1 - - comment:mint|function:Involved in mediating U snRNA export from the nucleus. Binds to 5' capped mRNA figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:AM46TpEPMDC2Ix3BtphOehTwju410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8R1B4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7466674|uniprotkb:Q8R3M7|intact:MINT-4608642|ensembl:ENSMUSP00000032992 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3c_mouse(display_long)|uniprotkb:Eif3c(gene name)|psi-mi:Eif3c(display_short)|uniprotkb:Eif3s8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_666312.1|ensembl:ENSMUSG00000030738(gene)|ensembl:ENSMUST00000032992(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q8R1B4|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 - - function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:t9Y/py75bSvLshPOxGcfrNASqeI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O88456 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8319447|uniprotkb:Q8VEK4|uniprotkb:Q3V0X5|uniprotkb:Q8CEI2|intact:MINT-4091916|uniprotkb:Q5BKQ2|uniprotkb:Q9R1C5 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:cpns1_mouse(display_long)|uniprotkb:Capns1(gene name)|psi-mi:Capns1(display_short)|uniprotkb:Capn4(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR018247|refseq:NP_033925.2|refseq:XP_006539551.1|interpro:IPR029642|mint:O88456|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0044877"(protein-containing complex binding)|reactome:R-MMU-1474228 - - function:Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction|comment:mint figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:oqdh38NnMwhwCJg6u+FTLv8ecd810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q501J6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-911206|uniprotkb:Q6P5G1|uniprotkb:Q8BIN2|ensembl:ENSMUSP00000155307 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ddx17_mouse(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:Ddx17(gene name)|psi-mi:Ddx17(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001035277.1|refseq:NP_951061.1|refseq:NP_951062.1|ensembl:ENSMUSG00000055065(gene)|ensembl:ENSMUST00000229877(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0061614"(miRNA transcription)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q501J6|reactome:R-MMU-3899300 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:uGXMsVmy7MWcTaJPNlkof05dS8I10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q99LF4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6261036|ensembl:ENSMUSP00000001834|uniprotkb:Q3UDW6|uniprotkb:Q3TI25|uniprotkb:Q3TA04 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rtcb_mouse(display_long)|uniprotkb:Rtcb(gene name)|psi-mi:Rtcb(display_short)|uniprotkb:D10Wsu52e(gene name synonym)|uniprotkb:Focal adhesion-associated protein(gene name synonym)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000001783(gene)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q99LF4|ensembl:ENSMUST00000001834(transcript)|refseq:NP_663397.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ISQNiLQA7DCcgBkTueMDhUHrkFQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BUN5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2337983|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q8BX84|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|ensembl:ENSMUSP00000034973 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:smad3_mouse(display_long)|uniprotkb:Smad3(gene name)|psi-mi:Smad3(display_short)|uniprotkb:Madh3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_058049.3|dip:DIP-29717N|ensembl:ENSMUSG00000032402(gene)|ensembl:ENSMUST00000034973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|reactome:R-MMU-1181150|reactome:R-MMU-1502540|reactome:R-MMU-2173788|reactome:R-MMU-2173789|reactome:R-MMU-2173795|reactome:R-MMU-2173796|reactome:R-MMU-5689880|reactome:R-MMU-8941855|reactome:R-MMU-9617828 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:47/62Iz3MOJAyDNCYtisL+unRDg10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q91V41 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-3869482|ensembl:ENSMUSP00000028238 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rab14_mouse(display_long)|uniprotkb:Rab14(gene name)|psi-mi:Rab14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_080973.1|ensembl:ENSMUST00000028238(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045176"(apical protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|mint:Q91V41|reactome:R-MMU-1660499|reactome:R-MMU-6798695|reactome:R-MMU-8873719|reactome:R-MMU-8876198|ensembl:ENSMUSG00000026878(gene) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:qFP8UXDCPt/RcLTWlZLaitH2LF410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62141 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-352338|uniprotkb:P37140|uniprotkb:Q3TBE5|uniprotkb:Q3TL90|uniprotkb:Q542E7|uniprotkb:Q8C285|uniprotkb:Q9DBY2|ensembl:ENSMUSP00000015100|ensembl:ENSMUSP00000144047 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pp1b_mouse(display_long)|uniprotkb:Ppp1cb(gene name)|psi-mi:Ppp1cb(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_766295.2|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62141|reactome:R-MMU-2565942|reactome:R-MMU-5625740|reactome:R-MMU-5627123|reactome:R-MMU-5673000|ensembl:ENSMUSG00000014956(gene)|ensembl:ENSMUST00000015100(transcript)|ensembl:ENSMUST00000201360(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:VtNJVyimeiEuRDDWtGswTqoSOH810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q61823 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-296473|uniprotkb:P97296|uniprotkb:Q3T9A9|ensembl:ENSMUSP00000025931|ensembl:ENSMUSP00000073975|ensembl:ENSMUSP00000133135 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pdcd4_mouse(display_long)|uniprotkb:Pdcd4(gene name)|psi-mi:Pdcd4(display_short)|uniprotkb:Ma3(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed protein(gene name synonym)|uniprotkb:Protein MA-3(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007569"(cell aging)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0005829"(cytosol)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|ensembl:ENSMUSG00000024975(gene)|ensembl:ENSMUST00000025931(transcript)|ensembl:ENSMUST00000074371(transcript)|ensembl:ENSMUST00000165617(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039778|mint:Q61823|rcsb pdb:2HM8|rcsb pdb:2IOL|rcsb pdb:2ION|rcsb pdb:2IOS|rcsb pdb:2KZT|rcsb pdb:2NSZ|rcsb pdb:3EIQ|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|refseq:NP_001161963.1|refseq:NP_001161964.1|refseq:NP_035180.2|refseq:XP_006526825.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ruEZtMgfVyIslPFdsTmuOfZhwuM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q3UIK4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-16089028|ensembl:ENSMUSP00000029759|uniprotkb:Q6ZPL2|uniprotkb:Q80UR9 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:met14_mouse(display_long)|uniprotkb:Mettl14(gene name)|psi-mi:Mettl14(display_short)|uniprotkb:Kiaa1627(gene name synonym)|uniprotkb:Methyltransferase-like protein 14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000028114(gene)|ensembl:ENSMUST00000029759(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|reactome:R-MMU-72203|refseq:NP_964000.2|dip:DIP-60725N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:GkIq08a+ap+vZiqnQ/dOGbnCUww10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P16627 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1183684|uniprotkb:O88686|uniprotkb:Q61693|ensembl:ENSMUSP00000007248 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hs71l_mouse(display_long)|uniprotkb:Heat shock 70 kDa-like protein 1(gene name synonym)|uniprotkb:Spermatid-specific heat shock protein 70(gene name synonym)|uniprotkb:Hspa1l(gene name)|psi-mi:Hspa1l(display_short)|uniprotkb:Hsc70t(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_038586.2|ensembl:ENSMUSG00000007033(gene)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|ensembl:ENSMUST00000007248(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|reactome:R-MMU-3371453|reactome:R-MMU-3371497|reactome:R-MMU-3371568|reactome:R-MMU-3371571 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:9AyTRM+TusngYdweWsTK46QlIgk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O88487 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-776055|uniprotkb:Q3TGH7|ensembl:ENSMUSP00000080410|ensembl:ENSMUSP00000107766 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dc1i2_mouse(display_long)|uniprotkb:Cytoplasmic dynein intermediate chain 2(gene name synonym)|uniprotkb:Dynein intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:Dync1i2(gene name)|psi-mi:Dync1i2(display_short)|uniprotkb:Dncic2(gene name synonym)|uniprotkb:Dnci2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001185805.1|refseq:NP_001185806.1|refseq:NP_001185807.1|refseq:NP_034194.1|ensembl:ENSMUSG00000027012(gene)|ensembl:ENSMUST00000081710(transcript)|ensembl:ENSMUST00000112138(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0010970"(transport along microtubule)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0031982"(vesicle)|go:"GO:0036157"(outer dynein arm)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025956|interpro:IPR036322|mint:O88487|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:HNendRwA8vyel0CUvmphdxZ7psk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q60817 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-494674|uniprotkb:Q3THR6|uniprotkb:Q4FZL8|ensembl:ENSMUSP00000073532 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:naca_mouse(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:Alpha-NAC/1.9.2(gene name synonym)|uniprotkb:Naca(gene name)|psi-mi:Naca(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001269905.1|refseq:NP_038636.2|ensembl:ENSMUSG00000061315(gene)|ensembl:ENSMUST00000073868(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042060"(wound healing)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051451"(myoblast migration)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:1901227"(negative regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:baQnjY8mAho/qN+/clg+YBjE8zw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9EQ32 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-643949|uniprotkb:Q2KHL6|uniprotkb:Q3TBW6|uniprotkb:Q3TC39|uniprotkb:Q3U5J3|uniprotkb:Q8BN25|uniprotkb:Q8C2Y4|ensembl:ENSMUSP00000052777 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:bcap_mouse(display_long)|uniprotkb:Bcap(gene name synonym)|uniprotkb:B-cell phosphoinositide 3-kinase adapter protein 1(gene name synonym)|uniprotkb:B-cell adapter for phosphoinositide 3-kinase(gene name synonym)|uniprotkb:Pik3ap1(gene name)|psi-mi:Pik3ap1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_113553.1|ensembl:ENSMUSG00000025017(gene)|ensembl:ENSMUST00000059672(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034123"(positive regulation of toll-like receptor signaling pathway)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0050727"(regulation of inflammatory response)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR017893|interpro:IPR035897|interpro:IPR041340|mint:Q9EQ32|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-983695|go:"GO:0016020"(membrane)|refseq:XP_006527535.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:v5h9ImhUFjH726+rFktPxbfsgA810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O09012 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-646301|uniprotkb:Q3UM58|uniprotkb:Q8K2V5|uniprotkb:Q91YC7|ensembl:ENSMUSP00000049132|ensembl:ENSMUSP00000108151 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pex5_mouse(display_long)|uniprotkb:Peroxisome receptor 1(gene name synonym)|uniprotkb:Peroxisomal C-terminal targeting signal import receptor(gene name synonym)|uniprotkb:PTS1-BP(gene name synonym)|uniprotkb:Peroxin-5(gene name synonym)|uniprotkb:PXR1P(gene name synonym)|uniprotkb:Pex5(gene name)|psi-mi:Pex5(display_short)|uniprotkb:Pxr1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033021.2|refseq:NP_787947.1|refseq:NP_001264734.1|refseq:XP_006505821.1|refseq:XP_006505822.1|refseq:NP_001264259.1|refseq:XP_017176951.1|ensembl:ENSMUSG00000005069(gene)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|ensembl:ENSMUST00000035861(transcript)|ensembl:ENSMUST00000112532(transcript)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051262"(protein tetramerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|interpro:IPR024113|reactome:R-MMU-8866654|go:"GO:0000038"(very long-chain fatty acid metabolic process)|reactome:R-MMU-9033241|reactome:R-MMU-9664873|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0001764"(neuron migration)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:GqfIILxRcIiR64Sc7t0ElWui3dw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P68510 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-444641|uniprotkb:P11576|uniprotkb:P70198|uniprotkb:Q3TGZ9|ensembl:ENSMUSP00000019109 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:1433f_mouse(display_long)|uniprotkb:Ywhah(gene name)|psi-mi:Ywhah(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035868.1|ensembl:ENSMUSG00000018965(gene)|ensembl:ENSMUST00000019109(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P68510|rcsb pdb:5YQG|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Ew2uUYIXrZ8nnP52xMnGB6KOCqc10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:B2RXR6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-11566298|uniprotkb:B2RXN6|uniprotkb:B7ZWK8|ensembl:ENSMUSP00000137616 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:anr44_mouse(display_long)|uniprotkb:Ankyrin repeat domain-containing protein 44(gene name synonym)|uniprotkb:Ankrd44(gene name)|psi-mi:Ankrd44(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001074902.2|ensembl:ENSMUSG00000052331(gene)|ensembl:ENSMUST00000179030(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:u2gh8Mr3OLcC72DfwHC0bMCFj3c10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VBV3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-11518619|ensembl:ENSMUSP00000043519 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:exos2_mouse(display_long)|uniprotkb:Exosome component 2(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosc2(gene name)|psi-mi:Exosc2(display_short)|uniprotkb:Rrp4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_659135.1|ensembl:ENSMUSG00000039356(gene)|ensembl:ENSMUST00000038474(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|reactome:R-MMU-429958|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:klb8UR3JlUw0bF1VjYSY+RkcmR410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q7TQ62 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17171056|ensembl:ENSMUSP00000048962|ensembl:ENSMUSP00000102319|ensembl:ENSMUSP00000102320|uniprotkb:A2A8F3|uniprotkb:Q8BM45 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:podn_mouse(display_long)|uniprotkb:Podn(gene name)|psi-mi:Podn(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000028600(gene)|ensembl:ENSMUST00000044248(transcript)|ensembl:ENSMUST00000106708(transcript)|ensembl:ENSMUST00000106709(transcript)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR026906|interpro:IPR032675|refseq:NP_001272885.1|refseq:NP_001272887.1|refseq:NP_766462.2|refseq:XP_006503155.1|refseq:XP_011238834.1|refseq:XP_011238835.1|refseq:XP_011238836.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:JChprhnFQQEsp+PMS3OKMsZUFk010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O09110 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-400768|uniprotkb:P97293|uniprotkb:Q91VX1|ensembl:ENSMUSP00000019076 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:mp2k3_mouse(display_long)|uniprotkb:Map2k3(gene name)|psi-mi:Map2k3(display_short)|uniprotkb:Mkk3(gene name synonym)|uniprotkb:Prkmk3(gene name synonym)|uniprotkb:MAPK/ERK kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_032954.1|ensembl:ENSMUSG00000018932(gene)|ensembl:ENSMUST00000019076(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O09110|rcsb pdb:1LEZ|reactome:R-MMU-2559580|reactome:R-MMU-450302 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:f8I+CsCs0RRfsw8LzciofYcw89U10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6ZWX6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q5KU39 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-775832|uniprotkb:Q3TPS1|uniprotkb:Q80V99|uniprotkb:Q8BKK6|uniprotkb:Q8CG01|uniprotkb:Q8CJC3|uniprotkb:Q05AE9|ensembl:ENSMUSP00000072729 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vps41_mouse(display_long)|uniprotkb:VAM2 homolog(gene name synonym)|uniprotkb:Vps41(gene name)|psi-mi:Vps41(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_742118.3|ensembl:ENSMUSG00000041236(gene)|ensembl:ENSMUST00000072961(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0071439"(clathrin complex)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322|mint:Q5KU39 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:4BCbF9r5rJSrFJohG7Rc9/2FnMQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q505D1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4286346|ensembl:ENSMUSP00000014640 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:anr28_mouse(display_long)|uniprotkb:Ankrd28(gene name)|psi-mi:Ankrd28(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001019775.1|ensembl:ENSMUSG00000014496(gene)|ensembl:ENSMUST00000014640(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-MMU-171319|reactome:R-MMU-204005 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:jhZYM9tAWCCd4hV3c/YAyNi0Y3s10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9QYI5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170998|ensembl:ENSMUSP00000140566|uniprotkb:Q3TB24|uniprotkb:Q8BPF6|uniprotkb:Q921S2 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dnjb2_mouse(display_long)|uniprotkb:DnaJ homolog subfamily B member 10(gene name synonym)|uniprotkb:mDj8(gene name synonym)|uniprotkb:Dnajb2(gene name)|psi-mi:Dnajb2(display_short)|uniprotkb:Dnajb10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016234"(inclusion body)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042026"(protein refolding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070628"(proteasome binding)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0090086"(negative regulation of protein deubiquitination)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:1903644"(regulation of chaperone-mediated protein folding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR018253|interpro:IPR036869|interpro:IPR043183|ensembl:ENSMUSG00000026203(gene)|ensembl:ENSMUST00000188931(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001153355.1|refseq:NP_001153356.1|refseq:NP_001153357.1|refseq:NP_064662.2|refseq:NP_835156.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:LO4vDj/DySxSGJpizJWcRdmpiAQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q91VC3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2552399|ensembl:ENSMUSP00000026667|uniprotkb:Q3UD29|uniprotkb:Q3TEZ8|uniprotkb:B2RY38|uniprotkb:Q8BVY3 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:if4a3_mouse(display_long)|uniprotkb:Eif4a3(gene name)|psi-mi:Eif4a3(display_short)|uniprotkb:Ddx48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 reactome:R-MMU-975957|ensembl:ENSMUSG00000025580(gene)|ensembl:ENSMUST00000026667(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|refseq:NP_619610.1|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q91VC3|reactome:R-MMU-1169408|reactome:R-MMU-159236|reactome:R-MMU-429947|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6jjMHbLWWbe2j3Qv+g8b/PbY7Ps10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8C854 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4285350|uniprotkb:Q6ZPT3|uniprotkb:Q8QZZ1|uniprotkb:Q60690|uniprotkb:Q6P930|ensembl:ENSMUSP00000123088 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:myef2_mouse(display_long)|uniprotkb:Myef2(gene name)|psi-mi:Myef2(display_short)|uniprotkb:Kiaa1341(gene name synonym)|uniprotkb:Mef2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001155889.1|refseq:XP_006498947.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034630|interpro:IPR034631|interpro:IPR034632|interpro:IPR035979|interpro:IPR000504(RNA recognition motif, RNP-1)|mint:Q8C854|ensembl:ENSMUSG00000027201(gene)|ensembl:ENSMUST00000152367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|refseq:XP_017171620.1|refseq:XP_017171621.1|refseq:XP_017171623.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ZnM8NqQUhlLdO7gzhs09ckrZUPw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9DBR0 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4285802|uniprotkb:Q9R0L8|ensembl:ENSMUSP00000002699 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:akap8_mouse(display_long)|uniprotkb:Akap8(gene name)|psi-mi:Akap8(display_short)|uniprotkb:Akap95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000024045(gene)|ensembl:ENSMUST00000002699(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9DBR0|refseq:NP_062748.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:CboiIO6b/r8YM0jLmJbCdzg5S3U10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q62318 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-346909|uniprotkb:P70391|uniprotkb:Q8C283|uniprotkb:Q99PN4|ensembl:ENSMUSP00000005705 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tif1b_mouse(display_long)|uniprotkb:Trim28(gene name)|psi-mi:Trim28(display_short)|uniprotkb:Krip1(gene name synonym)|uniprotkb:Tif1b(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:KRAB-A-interacting protein(gene name synonym)|uniprotkb:KRIP-1(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:Kap1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035718.2|dip:DIP-31477N|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q62318|rcsb pdb:6O5K|reactome:R-MMU-212436|ensembl:ENSMUSG00000005566(gene)|ensembl:ENSMUST00000005705(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:DvGJxQNohVWs++QEAyrqe4ngcz810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O35737 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-299747|ensembl:ENSMUSP00000070503|ensembl:ENSMUSP00000104770 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hnrh1_mouse(display_long)|uniprotkb:Hnrnph1(gene name)|psi-mi:Hnrnph1(display_short)|uniprotkb:Hnrph(gene name synonym)|uniprotkb:Hnrph1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000007850(gene)|ensembl:ENSMUST00000069304(transcript)|ensembl:ENSMUST00000109142(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:O35737|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:NP_067485.1|refseq:XP_017170179.1|refseq:XP_017170180.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:nBSCiXDDfkwqslFAXPXlDzC+5e410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P05213 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9Z1D1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-642408|uniprotkb:Q9R079|ensembl:ENSMUSP00000004206 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3g_mouse(display_long)|uniprotkb:Eif3s4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym)|uniprotkb:Eif3g(gene name)|psi-mi:Eif3g(display_short)|uniprotkb:Eif3p42(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_058572.2|ensembl:ENSMUSG00000070319(gene)|ensembl:ENSMUST00000004206(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:Q9Z1D1|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Tg6eCPZZkVgKsOicPmasuzr8gYs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q5XJE5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2898760|uniprotkb:E9QPK8|ensembl:ENSMUSP00000046905|uniprotkb:Q640R1 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:leo1_mouse(display_long)|uniprotkb:Leo1(gene name)|psi-mi:Leo1(display_short)|uniprotkb:Gm185(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|reactome:R-MMU-112382|reactome:R-MMU-201722|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSMUSG00000042487(gene)|ensembl:ENSMUST00000048937(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|refseq:NP_001034611.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:OgXix8fD8tBcMPOSGVGv+j6XZCg10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6XUX1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170963|ensembl:ENSMUSP00000035358|uniprotkb:Q3ULK4|uniprotkb:Q5EBN5|uniprotkb:Q8C7D4|uniprotkb:Q8C923|uniprotkb:Q9CTP7 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dusty_mouse(display_long)|uniprotkb:Dusty protein kinase(gene name synonym)|uniprotkb:Receptor-interacting serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:Dstyk(gene name)|psi-mi:Dstyk(display_short)|uniprotkb:Ripk5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000042046(gene)|ensembl:ENSMUST00000045110(transcript)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0005524"(ATP binding)|refseq:NP_766104.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:0Qq+16GF206jlZu+1LvUfpX2wro10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q3ULZ2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170945|ensembl:ENSMUSP00000088525|ensembl:ENSMUSP00000103317|uniprotkb:B9EHC4|uniprotkb:Q69ZC2|uniprotkb:Q8C0A0 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:fhdc1_mouse(display_long)|uniprotkb:Inf1(gene name synonym)|uniprotkb:Inverted formin-1(gene name synonym)|uniprotkb:Fhdc1(gene name)|psi-mi:Fhdc1(display_short)|uniprotkb:Kiaa1727(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000041842(gene)|ensembl:ENSMUST00000091002(transcript)|ensembl:ENSMUST00000107689(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0008017"(microtubule binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0060271"(cilium assembly)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR042201|refseq:NP_001028473.2|refseq:NP_001192284.1|refseq:XP_006501391.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:C9wsoaRcOrR+PmsU1/3gpekhqWw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BK63 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-771679|uniprotkb:Q64506|uniprotkb:Q80XI2|uniprotkb:Q99LY3|uniprotkb:Q3UIL0|ensembl:ENSMUSP00000132083 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:kc1a_mouse(display_long)|uniprotkb:CK1(gene name synonym)|uniprotkb:Csnk1a1(gene name)|psi-mi:Csnk1a1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:XP_006526451.1|dip:DIP-32408N|ensembl:ENSMUSG00000024576(gene)|ensembl:ENSMUST00000165721(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042277"(peptide binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8BK63|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-4641262|reactome:R-MMU-5610785|reactome:R-MMU-5635838 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D2N9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-775818|uniprotkb:Q8BGT3|ensembl:ENSMUSP00000031388 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vp33a_mouse(display_long)|uniprotkb:Vps33a(gene name)|psi-mi:Vps33a(display_short)|uniprotkb:Bf(gene name synonym)|uniprotkb:Buff(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_084205.3|ensembl:ENSMUSG00000029434(gene)|ensembl:ENSMUST00000031388(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030220"(platelet formation)|go:"GO:0030897"(HOPS complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0033263"(CORVET complex)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043154|interpro:IPR043155 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:s6vAFad2GadGII3LbRmLS4UWw/o10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P29595 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-13953910|ensembl:ENSMUSP00000010520|ensembl:ENSMUSP00000130492 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:nedd8_mouse(display_long)|uniprotkb:Nedd8(gene name)|psi-mi:Nedd8(display_short)|uniprotkb:Nedd-8(gene name synonym)|uniprotkb:Neddylin(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 8(gene name synonym)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000010376(gene)|ensembl:ENSMUST00000010520(transcript)|ensembl:ENSMUST00000163750(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008104"(protein localization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045116"(protein neddylation)|refseq:NP_032709.1|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|reactome:R-MMU-2173789|reactome:R-MMU-5689603|reactome:R-MMU-8856825|reactome:R-MMU-8951664|reactome:R-MMU-917937 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:BaS58kNNexME0rwPEC5iquMorTM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P68369 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q61687 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2657527|intact:EBI-2658449|uniprotkb:A2ADH4|ensembl:ENSMUSP00000109203 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:atrx_mouse(display_long)|uniprotkb:Xnp(gene name synonym)|uniprotkb:ATP-dependent helicase ATRX(gene name synonym)|uniprotkb:HP1 alpha-interacting protein(gene name synonym)|uniprotkb:HP1-BP38 protein(gene name synonym)|uniprotkb:Heterochromatin protein 2(gene name synonym)|uniprotkb:X-linked nuclear protein(gene name synonym)|uniprotkb:Atrx(gene name)|psi-mi:Atrx(display_short)|uniprotkb:Hp1bp2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033556.2|interpro:IPR038718|interpro:IPR041430|mint:Q61687|reactome:R-MMU-9670095|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900112"(regulation of histone H3-K9 trimethylation)|go:"GO:1901581"(negative regulation of telomeric RNA transcription from RNA pol II promoter)|go:"GO:1901582"(positive regulation of telomeric RNA transcription from RNA pol II promoter)|go:"GO:1904908"(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025766|interpro:IPR027417|ensembl:ENSMUSG00000031229(gene)|ensembl:ENSMUST00000113573(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030900"(forebrain development)|go:"GO:0031297"(replication fork processing)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035128"(post-embryonic forelimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070615"|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0072711"(cellular response to hydroxyurea)|dip:DIP-55974N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:dZfE7Or8WAgkuHkmUcqC3UlWi7U10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q80TR8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4285919|uniprotkb:Q3UXD5|uniprotkb:Q6P1E2|uniprotkb:Q8CDY3|ensembl:ENSMUSP00000060025 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dcaf1_mouse(display_long)|uniprotkb:Dcaf1(gene name)|psi-mi:Dcaf1(display_short)|uniprotkb:Kiaa0800(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:Vprbp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001015507.1|ensembl:ENSMUSG00000040325(gene)|ensembl:ENSMUST00000055009(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990244"("histone kinase activity (H2A-T120 specific)")|go:"GO:1990245"(histone H2A-T120 phosphorylation)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|reactome:R-MMU-983168|refseq:XP_006511818.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:jD8ln64I0aDM46a1ga3PsXRZyzw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VCK3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170916|ensembl:ENSMUSP00000045901 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tbg2_mouse(display_long)|uniprotkb:Gamma-2-tubulin(gene name synonym)|uniprotkb:Tubg2(gene name)|psi-mi:Tubg2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000045007(gene)|ensembl:ENSMUST00000043654(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q8VCK3|reactome:R-MMU-380270|reactome:R-MMU-380320|refseq:NP_598789.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ebQHblMVkTKA8wnY1ae2fdPzx8I10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P99024 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9Z2X1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4283704|uniprotkb:Q5FWK2|uniprotkb:Q8BVU8|uniprotkb:Q8K2U9|uniprotkb:Q8R0E7|ensembl:ENSMUSP00000045048|ensembl:ENSMUSP00000126817|ensembl:ENSMUSP00000130023|ensembl:ENSMUSP00000136700|ensembl:ENSMUSP00000137632 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hnrpf_mouse(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001159899.1|refseq:NP_001159900.1|refseq:NP_001159901.1|refseq:NP_001159902.1|refseq:NP_001159903.1|refseq:NP_001159904.1|refseq:NP_598595.1|refseq:XP_006506892.1|ensembl:ENSMUSG00000042079(gene)|ensembl:ENSMUST00000035493(transcript)|ensembl:ENSMUST00000163168(transcript)|ensembl:ENSMUST00000167182(transcript)|ensembl:ENSMUST00000180020(transcript)|ensembl:ENSMUST00000180341(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|rcsb pdb:2DB1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|mint:Q9Z2X1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CQL1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-12514027|uniprotkb:Q78Y23 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:mgn2_mouse(display_long)|uniprotkb:Magohb(gene name)|psi-mi:Magohb(display_short)|uniprotkb:Magoh-rs1(gene name synonym)|uniprotkb:Magoh2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-975957|refseq:NP_079840.2|interpro:IPR004023(Mago nashi protein)|refseq:NP_001314789.1|interpro:IPR036605 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:jFLiWOV3BtMx29gvl2hWe3aZxpY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P09405 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-641864|uniprotkb:Q548M9|uniprotkb:Q61991|uniprotkb:Q8BQD8|uniprotkb:Q99K50|ensembl:ENSMUSP00000027438 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:nucl_mouse(display_long)|uniprotkb:Protein C23(gene name synonym)|uniprotkb:Ncl(gene name)|psi-mi:Ncl(display_short)|uniprotkb:Nuc(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035010.3|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990631"(ErbB-4 class receptor binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000232"(regulation of rRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P09405|reactome:R-MMU-6791226|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000026234(gene)|ensembl:ENSMUST00000027438(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:NkPifysnX6CafgtN+Ko/p4aBqGE10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q99NG0 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170894|uniprotkb:Q3UPJ1 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:arip4_mouse(display_long)|uniprotkb:Androgen receptor-interacting protein 4(gene name synonym)|uniprotkb:RAD54-like protein 2(gene name synonym)|uniprotkb:Steroid receptor-interacting SNF2 domain-containing protein-like(gene name synonym)|uniprotkb:Rad54l2(gene name)|psi-mi:Rad54l2(display_short)|uniprotkb:Arip4(gene name synonym)|uniprotkb:Srisnf2l(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_109655.2|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|interpro:IPR000330(SNF2-related)|interpro:IPR044573|interpro:IPR044574|interpro:IPR038718 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ixlrQv66YXsv8HCBBM5HUOcz3tA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P68372 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2553564|uniprotkb:P05217|uniprotkb:Q3UJ73|uniprotkb:Q3TKF0|uniprotkb:Q99JZ6|ensembl:ENSMUSP00000042342 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tbb4b_mouse(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000036752(gene)|ensembl:ENSMUST00000043584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045298"(tubulin complex)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68372|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|refseq:NP_666228.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P58043 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-9638431|ensembl:ENSMUSP00000030724 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:sesn2_mouse(display_long)|uniprotkb:Sesn2(gene name)|psi-mi:Sesn2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_659156.1|ensembl:ENSMUSG00000028893(gene)|ensembl:ENSMUST00000030724(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009749"(response to glucose)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032542"(sulfiredoxin activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046323"(glucose import)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070728"(leucine binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901031"(regulation of response to reactive oxygen species)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1990253"(cellular response to leucine starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|interpro:IPR006730("PA26 p53-induced protein (sestrin)")|interpro:IPR029032|mint:P58043|reactome:R-MMU-5628897|reactome:R-MMU-9639288 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6NEyjqFHWanDDNmCJ0P0y4IC7gM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BTW3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-3835562|uniprotkb:Q9CSR7|ensembl:ENSMUSP00000147696 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:exos6_mouse(display_long)|uniprotkb:Exosc6(gene name)|psi-mi:Exosc6(display_short)|uniprotkb:Mtr3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_082550.1|ensembl:ENSMUSG00000109941(gene)|ensembl:ENSMUST00000210390(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q8BTW3|reactome:R-MMU-429958|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:T1m4+ZV2a+vpfBOaDD8qU5cZ85c10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BJY1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-992094|uniprotkb:Q3UFV2|uniprotkb:Q8BMA9|uniprotkb:Q8VEE9|uniprotkb:A2AUB0|uniprotkb:Q5DU49|ensembl:ENSMUSP00000028225 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:psmd5_mouse(display_long)|uniprotkb:26S proteasome subunit S5B(gene name synonym)|uniprotkb:26S protease subunit S5 basic(gene name synonym)|uniprotkb:Psmd5(gene name)|psi-mi:Psmd5(display_short)|uniprotkb:Kiaa0072(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_542121.2|ensembl:ENSMUSG00000026869(gene)|ensembl:ENSMUST00000028225(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Dz/VLH1H3FYxw/hv1unwSHu1LCU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q920Q4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-775797|uniprotkb:A2BI91|uniprotkb:Q8R3C3|uniprotkb:Q99KZ4 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vps16_mouse(display_long)|uniprotkb:Vps16(gene name)|psi-mi:Vps16(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR016534(Vacuolar protein sorting-associated protein 16)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR006926(Vps16, N-terminal)|interpro:IPR038132|mint:Q920Q4|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030897"(HOPS complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033263"(CORVET complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051015"(actin filament binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0097352"(autophagosome maturation) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:7XQzmHj2pjKXXSGR6yOyO+cUjfg10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9JIX8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-3043817|uniprotkb:B8JJ87|ensembl:ENSMUSP00000022793|uniprotkb:Q9CSN7|uniprotkb:Q9CSR9|uniprotkb:Q9CSX7|uniprotkb:Q9R046|uniprotkb:Q9R047 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:acinu_mouse(display_long)|uniprotkb:Acin1(gene name)|psi-mi:Acin1(display_short)|uniprotkb:Acinus(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|ensembl:ENSMUSG00000022185(gene)|ensembl:ENSMUST00000022793(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032552|interpro:IPR034257|interpro:IPR035979|interpro:IPR036361|reactome:R-MMU-111465|mint:Q9JIX8|refseq:NP_001078942.2|refseq:NP_001229534.1|refseq:NP_062513.3|refseq:NP_075679.2|refseq:XP_006519361.1|refseq:XP_006519367.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:U5PP/rm/ISlOu/33tl61lOBoSBQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P68368 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2642970|uniprotkb:Q3TY31|uniprotkb:P05215|ensembl:ENSMUSP00000140657 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tba4a_mouse(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033473.1|ensembl:ENSMUSG00000026202(gene)|ensembl:ENSMUST00000186213(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68368|reactome:R-MMU-114608|reactome:R-MMU-190840|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-2132295 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:A2AQ19 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170863|ensembl:ENSMUSP00000028767|uniprotkb:Q08EC5 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rtf1_mouse(display_long)|uniprotkb:Rtf1(gene name)|psi-mi:Rtf1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000027304(gene)|ensembl:ENSMUST00000028767(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR004343(Plus-3)|interpro:IPR036128|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654|refseq:NP_084388.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:9rTZAKYCrvMcedfLtFjVIc4JtV810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q3UGC7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170843|ensembl:ENSMUSP00000028668 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ei3ja_mouse(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 1-A(gene name synonym)|uniprotkb:eIF-3-alpha-A(gene name synonym)|uniprotkb:eIF3 p35(gene name synonym)|uniprotkb:Eif3j1(gene name)|psi-mi:Eif3j1(display_short)|uniprotkb:Eif3s1-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000027236(gene)|ensembl:ENSMUST00000028668(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|mint:Q3UGC7|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|refseq:NP_653128.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:eibVbzmFcJ5qAD797IS+jZFKxvE10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O70172 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-644828|ensembl:ENSMUSP00000006912 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pi42a_mouse(display_long)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-alpha"(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-alpha(gene name synonym)|uniprotkb:Pip4k2a(gene name)|psi-mi:Pip4k2a(display_short)|uniprotkb:Pip5k2a(gene name synonym)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 5-Phosphate 4-Kinase(gene name synonym)|uniprotkb:Pi5p4ka(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_032871.3|ensembl:ENSMUSG00000026737(gene)|ensembl:ENSMUST00000006912(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090119"(vesicle-mediated cholesterol transport)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70172|reactome:R-MMU-1660499|reactome:R-MMU-6811555|reactome:R-MMU-6811558|reactome:R-MMU-8847453|dip:DIP-49438N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:tnXc4oMaOV1P8hQRrM6/4G5CPOQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P11672 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170801|ensembl:ENSMUSP00000053962|uniprotkb:Q3UE34 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ngal_mouse(display_long)|uniprotkb:Oncogene 24p3(gene name synonym)|uniprotkb:SV-40-induced 24p3 protein(gene name synonym)|uniprotkb:Lcn2(gene name)|psi-mi:Lcn2(display_short)|uniprotkb:Lipocalin-2(gene name synonym)|uniprotkb:Siderocalin LCN2(gene name synonym)|uniprotkb:p25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000026822(gene)|ensembl:ENSMUST00000050785(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0009617"(response to bacterium)|go:"GO:0009635"(response to herbicide)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015891"(siderophore transport)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0036094"(small molecule binding)|go:"GO:0042493"|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097577"(sequestering of iron ion)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903981"(enterobactin binding)|go:"GO:1904440"(positive regulation of iron ion import across plasma membrane)|go:"GO:1905956"(positive regulation of endothelial tube morphogenesis)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002345(Lipocalin)|interpro:IPR003087(Neutrophil gelatinase-associated lipocalin)|interpro:IPR012674(Calycin)|interpro:IPR022272|rcsb pdb:3S26|rcsb pdb:3U9P|reactome:R-MMU-6798695|reactome:R-MMU-6799990|reactome:R-MMU-917937|refseq:NP_032517.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:/1qxnGtMV08okrIVzR9F22V6bGU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O70456 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1544118|uniprotkb:Q3TEZ1|ensembl:ENSMUSP00000050374 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:1433s_mouse(display_long)|uniprotkb:Sfn(gene name)|psi-mi:Sfn(display_short)|uniprotkb:Mkrn3(gene name synonym)|uniprotkb:Stratifin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_061224.2|ensembl:ENSMUSG00000047281(gene)|ensembl:ENSMUST00000057311(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003334"(keratinocyte development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061436"(establishment of skin barrier)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR037435|mint:O70456|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-6804114|reactome:R-MMU-75035|reactome:R-MMU-9614399|go:"GO:0030307"(positive regulation of cell growth) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6B8XqFSuqdwWT6hYap/ecmwIuaY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62869 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2659323|uniprotkb:Q80W20|uniprotkb:Q63529|ensembl:ENSMUSP00000066210 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:elob_mouse(display_long)|uniprotkb:Elob(gene name)|psi-mi:Elob(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:Tceb2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_080581.1|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|go:"GO:0030891"(VCB complex)|interpro:IPR039049|mint:P62869|rcsb pdb:2FNJ|rcsb pdb:4JGH|reactome:R-MMU-112382|reactome:R-MMU-1234176|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-75955|reactome:R-MMU-8951664|reactome:R-MMU-9705462|reactome:R-MMU-983168|ensembl:ENSMUSG00000055839(gene)|ensembl:ENSMUST00000069579(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:7W4I9AcvS1GK89dMmBOImMYNgLY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62960 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-529779|uniprotkb:P22568|uniprotkb:P27817|uniprotkb:P43482|ensembl:ENSMUSP00000078589 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ybox1_mouse(display_long)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Ybx1(gene name)|psi-mi:Ybx1(display_short)|uniprotkb:Msy1(gene name synonym)|uniprotkb:Msy-1(gene name synonym)|uniprotkb:Yb1(gene name synonym)|uniprotkb:Nsep1(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035862.2|dip:DIP-34256N|ensembl:ENSMUSG00000028639(gene)|ensembl:ENSMUST00000079644(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P62960|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-9017802|go:"GO:0043025"(neuronal cell body) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:imkViHICtFj/0wQ8IDprza1b43010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q61074 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-642919|ensembl:ENSMUSP00000031032 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ppm1g_mouse(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:Fibroblast growth factor-inducible protein 13(gene name synonym)|uniprotkb:Ppm1g(gene name)|psi-mi:Ppm1g(display_short)|uniprotkb:Fin13(gene name synonym)|uniprotkb:Ppm1c(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_032040.1|ensembl:ENSMUSG00000029147(gene)|ensembl:ENSMUST00000031032(transcript)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q61074 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:OazpV/JqeZD+TpovURxYWY9t6VI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q60963 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2794278|uniprotkb:Q8BKM3|uniprotkb:Q921T4|ensembl:ENSMUSP00000024706 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pafa_mouse(display_long)|uniprotkb:Pla2g7(gene name)|psi-mi:Pla2g7(display_short)|uniprotkb:Pafah(gene name synonym)|uniprotkb:PAF 2-acylhydrolase(gene name synonym)|uniprotkb:LDL-associated phospholipase A2(gene name synonym)|uniprotkb:2-acetyl-1-alkylglycerophosphocholine esterase(gene name synonym)|uniprotkb:1-alkyl-2-acetylglycerophosphocholine esterase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_038765.2|refseq:XP_006524428.1|refseq:XP_006524429.1|ensembl:ENSMUSG00000023913(gene)|ensembl:ENSMUST00000024706(transcript)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034440"(lipid oxidation)|go:"GO:0034441"(plasma lipoprotein particle oxidation)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0062234"(platelet activating factor catabolic process)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR005065(Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II)|interpro:IPR016715(PAF acetylhydrolase)|interpro:IPR029058|reactome:R-MMU-422085 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:RVXoo2tSkq0UV2Ii+D82gPs76Ss10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P70372 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6877056|ensembl:ENSMUSP00000096549|ensembl:ENSMUSP00000146866|uniprotkb:Q60745|uniprotkb:Q78QY3 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:elav1_mouse(display_long)|uniprotkb:Elavl1(gene name)|psi-mi:Elavl1(display_short)|uniprotkb:Elra(gene name synonym)|uniprotkb:Hua(gene name synonym)|uniprotkb:Elav-like generic protein(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym)|uniprotkb:MelG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000040028(gene)|ensembl:ENSMUST00000098950(transcript)|ensembl:ENSMUST00000209010(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:P70372|reactome:R-MMU-450520|reactome:R-MMU-72163|go:"GO:0019901"(protein kinase binding)|refseq:XP_006508761.1|refseq:NP_034615.2|dip:DIP-46480N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:iKHrpZqi5b7EFLkfVJSRTpi9sj010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P97801 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-309807|uniprotkb:O09092|ensembl:ENSMUSP00000022147 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:smn_mouse(display_long)|uniprotkb:Smn1(gene name)|psi-mi:Smn1(display_short)|uniprotkb:Smn(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001239558.1|refseq:NP_035550.1|ensembl:ENSMUSG00000021645(gene)|ensembl:ENSMUST00000022147(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030018"(Z disc)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0032797"(SMN complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:P97801|reactome:R-MMU-191859 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:cTFjZc/daUP5J6lWPrCVM5ZsGeU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q80YR2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170789|ensembl:ENSMUSP00000022690|uniprotkb:Q6PED9|uniprotkb:Q8C1Y2 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:fhi2b_mouse(display_long)|uniprotkb:Fhip2b(gene name)|psi-mi:Fhip2b(display_short)|uniprotkb:Fam160b2(gene name synonym)|uniprotkb:Rai16(gene name synonym)|uniprotkb:Retinoic acid-induced protein 16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000022095(gene)|ensembl:ENSMUST00000022690(transcript)|interpro:IPR019384|refseq:NP_919326.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:rVqFodPZW1lM/PK6MH2FK4DS0YU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8CH77 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-16732405|uniprotkb:Q3U5B6|uniprotkb:Q68EE8|uniprotkb:Q6PB78|uniprotkb:Q80TI7|uniprotkb:Q8BKG2|uniprotkb:Q8BUT5|ensembl:ENSMUSP00000043803|ensembl:ENSMUSP00000067241 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:nav1_mouse(display_long)|uniprotkb:Pore membrane and/or filament-interacting-like protein 3(gene name synonym)|uniprotkb:Nav1(gene name)|psi-mi:Nav1(display_short)|uniprotkb:Kiaa1151(gene name synonym)|uniprotkb:Pomfil3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_775613.2|ensembl:ENSMUSG00000009418(gene)|ensembl:ENSMUST00000040599(transcript)|ensembl:ENSMUST00000067414(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007399"(nervous system development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043194"(axon initial segment)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR039041|mint:Q8CH77|go:"GO:0001578"(microtubule bundle formation) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6JEY5QgG5i9X72Lw1SklaXm186U10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BIX3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170766|ensembl:ENSMUSP00000028536|ensembl:ENSMUSP00000091409|uniprotkb:Q7TPE6|uniprotkb:Q9CZS0 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:al14e_mouse(display_long)|uniprotkb:Arl14ep(gene name)|psi-mi:Arl14ep(display_short)|uniprotkb:Arf7ep(gene name synonym)|uniprotkb:ARF7 effector protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000027122(gene)|ensembl:ENSMUST00000028536(transcript)|ensembl:ENSMUST00000093883(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR026515|interpro:IPR029264|refseq:NP_001020273.1|refseq:NP_776111.1|refseq:XP_006499149.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:MMERTRlru/43ctqyABHJ6HLUc6M10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P35279 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-444674|uniprotkb:Q542M6|uniprotkb:Q8R2Z7|uniprotkb:Q8VEE5|uniprotkb:Q9JJD4|ensembl:ENSMUSP00000032946 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rab6a_mouse(display_long)|uniprotkb:Rab6a(gene name)|psi-mi:Rab6a(display_short)|uniprotkb:Rab6(gene name synonym)|uniprotkb:MNCb-1660(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001157135.1|refseq:NP_077249.1|ensembl:ENSMUSG00000030704(gene)|ensembl:ENSMUST00000032946(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0018125"(peptidyl-cysteine methylation)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0051117"(ATPase binding)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P35279|reactome:R-MMU-6798695|reactome:R-MMU-6811436|reactome:R-MMU-6811440|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|dip:DIP-120N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:dvs8ZexwDDVZ3QFifBZ+id2D0+k10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P67871 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-348179|ensembl:ENSMUSP00000025246|ensembl:ENSMUSP00000134218|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q3TTJ7 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:csk2b_mouse(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Csnk2b(gene name)|psi-mi:Csnk2b(display_short)|uniprotkb:Ck2n(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000024387(gene)|ensembl:ENSMUST00000025246(transcript)|ensembl:ENSMUST00000173114(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67871|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6798695|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751|refseq:NP_034105.1|refseq:NP_001290374.1|dip:DIP-35573N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P61982 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-359843|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q4FK44|uniprotkb:Q3UFD6|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSMUSP00000051223|ensembl:ENSMUSP00000143631 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:1433g_mouse(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_061359.2|ensembl:ENSMUSG00000051391(gene)|ensembl:ENSMUST00000055808(transcript)|ensembl:ENSMUST00000198270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61982|reactome:R-MMU-111447|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-9614399 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q80T85 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170743|ensembl:ENSMUSP00000052755|uniprotkb:Q80VT3|uniprotkb:Q80ZW6|uniprotkb:Q8BIP8|uniprotkb:Q8BVK5|uniprotkb:Q8K0Q6 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dcaf5_mouse(display_long)|uniprotkb:Dcaf5(gene name)|psi-mi:Dcaf5(display_short)|uniprotkb:Kiaa1824(gene name synonym)|uniprotkb:Wdr22(gene name synonym)|uniprotkb:WD repeat-containing protein 22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000049106(gene)|ensembl:ENSMUST00000054145(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-MMU-8951664|refseq:NP_796241.3 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Vf9gw/cFaKtvaT0xEXa/Bh3cZB810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9ERD7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2255594|uniprotkb:Q3UF42|uniprotkb:Q5I036|ensembl:ENSMUSP00000071134 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tbb3_mouse(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_075768.1|dip:DIP-48419N|ensembl:ENSMUSG00000062380(gene)|ensembl:ENSMUST00000071134(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9ERD7|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q5SSL4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2310685|uniprotkb:Q3U5G0|uniprotkb:Q3UQJ6|uniprotkb:Q3UY38|uniprotkb:Q5SYJ5|uniprotkb:Q5SYJ7|uniprotkb:Q5SYJ8|uniprotkb:Q5SYJ9|uniprotkb:Q6PCY1|uniprotkb:Q6PDH3|ensembl:ENSMUSP00000072522 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:abr_mouse(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001333599.1|refseq:NP_001278115.1|refseq:NP_942597.1|refseq:NP_932135.1|refseq:NP_942598.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043314"(negative regulation of neutrophil degranulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060313"(negative regulation of blood vessel remodeling)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035892|interpro:IPR035899|interpro:IPR037769|interpro:IPR037865|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|ensembl:ENSMUSG00000017631(gene)|ensembl:ENSMUST00000072740(transcript)|go:"GO:0002692"(negative regulation of cellular extravasation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:rkYDNM1hPvcrtB4OrgtHGMK0NTs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P16254 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170722|ensembl:ENSMUSP00000009693|uniprotkb:Q3TIK2 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srp14_mouse(display_long)|uniprotkb:Srp14(gene name)|psi-mi:Srp14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000009549(gene)|ensembl:ENSMUST00000009693(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|rcsb pdb:1914|reactome:R-MMU-1799339|reactome:R-MMU-6798695|refseq:NP_033299.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:caCUnlTfiLv/3V45/vErqwIOn3o10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q99LL5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4285021|uniprotkb:Q9D6T6|ensembl:ENSMUSP00000001836 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pwp1_mouse(display_long)|uniprotkb:Pwp1(gene name)|psi-mi:Pwp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_598754.2|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q99LL5|ensembl:ENSMUSG00000001785(gene)|ensembl:ENSMUST00000001836(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:+p9Zt4WaArKLsgVszp/FIYBjhUU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CQR6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4286534|uniprotkb:A2ASL7|ensembl:ENSMUSP00000028087 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ppp6_mouse(display_long)|uniprotkb:Ppp6c(gene name)|psi-mi:Ppp6c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_077171.1|ensembl:ENSMUSG00000026753(gene)|ensembl:ENSMUST00000028087(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:Q9CQR6|reactome:R-MMU-171319|reactome:R-MMU-204005|go:"GO:0006470"(protein dephosphorylation) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:R0jsZoqJLoRaSNMNCLRkQ40CC+o10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:A2BDX3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170691|ensembl:ENSMUSP00000096670 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:mocs3_mouse(display_long)|uniprotkb:Mocs3(gene name)|psi-mi:Mocs3(display_short)|uniprotkb:Uba4(gene name synonym)|uniprotkb:Molybdenum cofactor synthesis protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000074576(gene)|ensembl:ENSMUST00000099071(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0042292"(URM1 activating enzyme activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0061604"(molybdopterin-synthase sulfurtransferase activity)|go:"GO:0061605"(molybdopterin-synthase adenylyltransferase activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR001763(Rhodanese-like)|interpro:IPR028885|interpro:IPR035985|interpro:IPR036873|reactome:R-MMU-947581|refseq:NP_001153802.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:MM7UhT5bTVjC1fAKhQkTykF12Aw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P59759 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-15626218 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:mrtfb_mouse(display_long)|uniprotkb:Mrtfb(gene name)|psi-mi:Mrtfb(display_short)|uniprotkb:MKL/myocardin-like protein 2(gene name synonym)|uniprotkb:Mkl2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001889"(liver development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051145"(smooth muscle cell differentiation)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004018(RPEL repeat)|interpro:IPR036361|interpro:IPR043451|refseq:NP_705816.2|dip:DIP-60885N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:cJN03eTsHX9mVW5HyxujbeTUSr010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P42669 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-773823|ensembl:ENSMUSP00000059404 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pura_mouse(display_long)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)|uniprotkb:Pura(gene name)|psi-mi:Pura(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033015.1|refseq:XP_006525787.1|refseq:XP_011245162.1|ensembl:ENSMUSG00000043991(gene)|ensembl:ENSMUST00000051301(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030500|mint:P42669 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:3LVZ5qdZYeJyeUVPhy3cozxROWs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P70333 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4282223|ensembl:ENSMUSP00000050838|ensembl:ENSMUSP00000074483|ensembl:ENSMUSP00000108827|ensembl:ENSMUSP00000108828|ensembl:ENSMUSP00000108829|uniprotkb:Q3THV9 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hnrh2_mouse(display_long)|uniprotkb:Hnrnph2(gene name)|psi-mi:Hnrnph2(display_short)|uniprotkb:Hnrph2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001300645.1|refseq:NP_001300646.1|uniprotkb:A2BDV8(uniprot-removed-ac)|ensembl:ENSMUST00000074950(transcript)|ensembl:ENSMUST00000113202(transcript)|ensembl:ENSMUST00000113203(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P70333|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUST00000059297(transcript)|ensembl:ENSMUSG00000045427(gene)|ensembl:ENSMUST00000050331(transcript)|refseq:NP_063921.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:BKLnU/p+g6hd6joRgjXU+BO5i7o10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BXR9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170664|ensembl:ENSMUSP00000107560|uniprotkb:Q8BYW2 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:osbl6_mouse(display_long)|uniprotkb:Osbpl6(gene name)|psi-mi:Osbpl6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000042359(gene)|ensembl:ENSMUST00000111929(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-MMU-192105|go:"GO:0005829"(cytosol)|refseq:NP_001277662.1|refseq:NP_001277663.1|refseq:NP_663500.2|refseq:XP_011238164.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:d4KJtVSPjJODK2Y3IfmTAb+FlYc10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q62093 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2550402|ensembl:ENSMUSP00000090059|ensembl:ENSMUSP00000120086|ensembl:ENSMUSP00000140016|uniprotkb:Q60701|uniprotkb:Q542L3 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srsf2_mouse(display_long)|uniprotkb:Sfrs2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym)|uniprotkb:Srsf2(gene name)|psi-mi:Srsf2(display_short)|uniprotkb:Pr264(gene name synonym)|uniprotkb:Sfrs10(gene name synonym)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:Putative myelin regulatory factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:XP_011247137.1|ensembl:ENSMUSG00000034120(gene)|ensembl:ENSMUST00000092404(transcript)|ensembl:ENSMUST00000136914(transcript)|ensembl:ENSMUST00000190993(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|interpro:IPR034893|interpro:IPR035979|mint:Q62093|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72187|reactome:R-MMU-73856|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_035488.1|dip:DIP-44831N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:/LUrJ8xa42APUsgH5ke590Kxsh810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CWF2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2794256|uniprotkb:Q3TG26|ensembl:ENSMUSP00000075178 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tbb2b_mouse(display_long)|uniprotkb:Tubb2b(gene name)|psi-mi:Tubb2b(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_076205.1|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9CWF2|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|ensembl:ENSMUSG00000045136(gene)|ensembl:ENSMUST00000075774(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:sluQMryNuOvp6xlV558+agiRwvE10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6WVG3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-16730134|uniprotkb:Q3T9E3 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:kcd12_mouse(display_long)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym)|uniprotkb:Kctd12(gene name)|psi-mi:Kctd12(display_short)|uniprotkb:Pfet1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043235"(receptor complex)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|mint:Q6WVG3|refseq:NP_808383.3|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:5S5rFCAvBhZVG47OqS29CXJxXP810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D6F9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-911077|uniprotkb:Q62364|uniprotkb:Q80Y54|ensembl:ENSMUSP00000071135 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tbb4a_mouse(display_long)|uniprotkb:Tubb4a(gene name)|psi-mi:Tubb4a(display_short)|uniprotkb:Tubb4(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033477.2|ensembl:ENSMUSG00000062591(gene)|ensembl:ENSMUST00000071135(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0030030"(cell projection organization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0033269"(internode region of axon)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR037103|mint:Q9D6F9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|interpro:IPR036525 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:mMveBNZkQs2x0dyHm/ghVWBe4/410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O08796 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170620|ensembl:ENSMUSP00000046595|ensembl:ENSMUSP00000102097|ensembl:ENSMUSP00000102098 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ef2k_mouse(display_long)|uniprotkb:Eef2k(gene name)|psi-mi:Eef2k(display_short)|uniprotkb:Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000035064(gene)|ensembl:ENSMUST00000047875(transcript)|ensembl:ENSMUST00000106488(transcript)|ensembl:ENSMUST00000106489(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004686"(elongation factor-2 kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990637"(response to prolactin)|interpro:IPR004166(MHCK/EF2 kinase)|interpro:IPR006597(Sel1-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR017400(Elongation factor 2 kinase)|reactome:R-MMU-166208|refseq:NP_001254639.1|refseq:NP_001254640.1|refseq:NP_031934.1|refseq:XP_006507405.1|refseq:XP_006507406.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ZY+VZtSEPfdyBdtngMDuhyKw5oA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62320 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2550316|ensembl:ENSMUSP00000020397|uniprotkb:P43331|uniprotkb:Q3TV81 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:smd3_mouse(display_long)|uniprotkb:Snrpd3(gene name)|psi-mi:Snrpd3(display_short)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000020180(gene)|ensembl:ENSMUST00000020397(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|reactome:R-MMU-73856|reactome:R-MMU-77588|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|mint:P62320|reactome:R-MMU-111367|reactome:R-MMU-191859|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_080371.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:WkrSZVfVmSQrJYfy7mwp48xjsVA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62259 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q920B9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2549823|uniprotkb:Q3TZ48|uniprotkb:Q3UFH0|uniprotkb:Q921H4 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:sp16h_mouse(display_long)|uniprotkb:Supt16h(gene name)|psi-mi:Supt16h(display_short)|uniprotkb:Fact140(gene name synonym)|uniprotkb:Factp140(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:Supt16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|interpro:IPR029148|reactome:R-MMU-6804756|reactome:R-MMU-75955|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|refseq:NP_291096.2|dip:DIP-55972N|mint:Q920B9 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:qcl0ckY0w3tIem/ezLyPtHVUnZA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9JLM8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-771719|uniprotkb:Q6P207|ensembl:ENSMUSP00000050034 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dclk1_mouse(display_long)|uniprotkb:Doublecortin-like and CAM kinase-like 1(gene name synonym)|uniprotkb:Dclk1(gene name)|psi-mi:Dclk1(display_short)|uniprotkb:Dclk(gene name synonym)|uniprotkb:Dcamkl1(gene name synonym)|uniprotkb:Doublecortin-like kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_064362.1|ensembl:ENSMUSG00000027797(gene)|ensembl:ENSMUST00000054237(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030900"(forebrain development)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036572|mint:Q9JLM8 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:P3ZZ2GyKcdMimAcekZ8OlLbuciM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q60737 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P07214 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1635010|ensembl:ENSMUSP00000018737|ensembl:ENSMUSP00000151000 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:sprc_mouse(display_long)|uniprotkb:Sparc(gene name)|psi-mi:Sparc(display_short)|uniprotkb:Secreted protein acidic and rich in cysteine(gene name synonym)|uniprotkb:Osteonectin(gene name synonym)|uniprotkb:Basement-membrane protein 40(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033268.1|ensembl:ENSMUSG00000018593(gene)|ensembl:ENSMUST00000018737(transcript)|ensembl:ENSMUST00000214685(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043473"(pigmentation)|go:"GO:0045202"(synapse)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001999(Osteonectin-like, conserved site)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|interpro:IPR037641|mint:P07214|reactome:R-MMU-114608|reactome:R-MMU-3000178|reactome:R-MMU-3000497 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:1bxIUD08asD8bUNWlQgC3ha5Jr010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9R020 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170596|ensembl:ENSMUSP00000101673|uniprotkb:Q3TI29|uniprotkb:Q3TLF5|uniprotkb:Q3TUB7|uniprotkb:Q3UD16 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:zrab2_mouse(display_long)|uniprotkb:Zranb2(gene name)|psi-mi:Zranb2(display_short)|uniprotkb:Zfp265(gene name synonym)|uniprotkb:Zis(gene name synonym)|uniprotkb:Znf265(gene name synonym)|uniprotkb:Zinc finger protein 265(gene name synonym)|uniprotkb:Zinc finger, splicing(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000028180(gene)|ensembl:ENSMUST00000106058(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR017337(Uncharacterised conserved protein UCP037956, zinc finger Ran-binding)|interpro:IPR036443|refseq:NP_059077.1|refseq:XP_017175137.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:I011hvNKqlA0Aik3EmXkL2HKQbc10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q0P678 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4285772|uniprotkb:Q3TKW3|uniprotkb:Q52KI3|uniprotkb:Q6KAL8|uniprotkb:Q9CU64|ensembl:ENSMUSP00000090761 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:zch18_mouse(display_long)|uniprotkb:Zc3h18(gene name)|psi-mi:Zc3h18(display_short)|uniprotkb:Nhn1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUST00000093073(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0050779"(RNA destabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|refseq:NP_001025164.1|refseq:NP_001025165.1|refseq:NP_001297579.1|ensembl:ENSMUSG00000017478(gene) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:yQXtDYpTOE6hdaKBFQskL/GDgvw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9QZ08 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-647173|ensembl:ENSMUSP00000042026 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:nagk_mouse(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:Nagk(gene name)|psi-mi:Nagk(display_short)|uniprotkb:Gnk(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_062415.1|ensembl:ENSMUSG00000034744(gene)|ensembl:ENSMUST00000037376(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0009384"(N-acylmannosamine kinase activity)|go:"GO:0019262"(N-acetylneuraminate catabolic process)|go:"GO:0045127"(N-acetylglucosamine kinase activity)|interpro:IPR002731(ATPase, BadF/BadG/BcrA/BcrD type)|interpro:IPR039758|interpro:IPR043129|reactome:R-MMU-446210|go:"GO:0006044"(N-acetylglucosamine metabolic process) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Zgfnld0VfSLTH+RsOAKYIlWhhv810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62317 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6665916|ensembl:ENSMUSP00000037597|uniprotkb:P43330 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:smd2_mouse(display_long)|uniprotkb:Snrpd2(gene name)|psi-mi:Snrpd2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000040824(gene)|ensembl:ENSMUST00000049294(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62317|reactome:R-MMU-191859|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_081219.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8K1R7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2553319|uniprotkb:Q148U2|ensembl:ENSMUSP00000049056|uniprotkb:Q8R3P1 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:nek9_mouse(display_long)|uniprotkb:Nek9(gene name)|psi-mi:Nek9(display_short)|uniprotkb:Nercc(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 9(gene name synonym)|uniprotkb:Nercc1 kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000034290(gene)|ensembl:ENSMUST00000040992(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007049"(cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011009(Protein kinase-like)|interpro:IPR042767|mint:Q8K1R7|rcsb pdb:5DE2|reactome:R-MMU-2980767|refseq:NP_660120.2|dip:DIP-56880N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:HVtKV0f4KRYqJ5BTuVohMgrJS6A10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O35381 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-643140|uniprotkb:P97437|ensembl:ENSMUSP00000082652 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:an32a_mouse(display_long)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Anp32a(gene name)|psi-mi:Anp32a(display_short)|uniprotkb:Anp32(gene name synonym)|uniprotkb:Lanp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033802.2|ensembl:ENSMUSG00000032249(gene)|ensembl:ENSMUST00000085519(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:O35381|rcsb pdb:2JQD|reactome:R-MMU-450520 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:flk6xO1N5PloQyQ9bOBHDzr3Hr010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8K2T8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-642477|uniprotkb:Q3UY97|uniprotkb:Q9CS63|uniprotkb:Q9JJ99|ensembl:ENSMUSP00000003529 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:paf1_mouse(display_long)|uniprotkb:Paf1(gene name)|psi-mi:Paf1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_062331.2|ensembl:ENSMUSG00000003437(gene)|ensembl:ENSMUST00000003529(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8K2T8|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:1cFGAVgb19bf33BaPcIowpXT5qc10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q62018 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-644452|uniprotkb:Q3UFF5|uniprotkb:Q3UY40|uniprotkb:Q66JX4|uniprotkb:Q7TPS6|uniprotkb:Q8BND9|uniprotkb:Q8BRD1|uniprotkb:Q8C9W7|uniprotkb:Q8C9Y3|uniprotkb:Q8CHI1|ensembl:ENSMUSP00000005749 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ctr9_mouse(display_long)|uniprotkb:SH2 domain-binding protein 1(gene name synonym)|uniprotkb:Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa(gene name synonym)|uniprotkb:Ctr9(gene name)|psi-mi:Ctr9(display_short)|uniprotkb:Kiaa0155(gene name synonym)|uniprotkb:Sh2bp1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033457.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0005634"(nucleus)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q62018|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654|go:"GO:0071222"(cellular response to lipopolysaccharide)|ensembl:ENSMUSG00000005609(gene)|ensembl:ENSMUST00000005749(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:D1n7ZSSSZL7dLYvcuEkIkttdmg810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q5FWK3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q08943 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2657613|uniprotkb:Q3U9Z2|uniprotkb:Q3UJ75|uniprotkb:Q4V9U4|uniprotkb:Q8CGA6|ensembl:ENSMUSP00000076971|ensembl:ENSMUSP00000127058 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ssrp1_mouse(display_long)|uniprotkb:Ssrp1(gene name)|psi-mi:Ssrp1(display_short)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001129553.1|refseq:NP_892035.2|refseq:XP_006499133.1|ensembl:ENSMUSG00000027067(gene)|ensembl:ENSMUST00000077798(transcript)|ensembl:ENSMUST00000168266(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08943|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6804756|reactome:R-MMU-75955 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:QLbUR9V6OGtMwfD2fiZy4wEJwWE10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9ES74 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-16193749|ensembl:ENSMUSP00000140635|ensembl:ENSMUSP00000140903|uniprotkb:Q3UEV7 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:nek7_mouse(display_long)|uniprotkb:Nek7(gene name)|psi-mi:Nek7(display_short)|uniprotkb:Never in mitosis A-related kinase 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000026393(gene)|ensembl:ENSMUST00000186017(transcript)|ensembl:ENSMUST00000187407(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0046872"(metal ion binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001298077.1|refseq:NP_067618.1|dip:DIP-61936N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:yBeflCTdZ/ulJfZ7zTfROYAd/FQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9ERF3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6094557|uniprotkb:Q3U562|uniprotkb:Q9CZP1|ensembl:ENSMUSP00000056359|ensembl:ENSMUSP00000113560 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:wdr61_mouse(display_long)|uniprotkb:Wdr61(gene name)|psi-mi:Wdr61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001020546.1|refseq:NP_075680.1|ensembl:ENSMUSG00000061559(gene)|ensembl:ENSMUST00000051822(transcript)|ensembl:ENSMUST00000121204(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERF3|reactome:R-MMU-112382|reactome:R-MMU-429958|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:r5TxJiuiFNk5dUDuhzCqFfFXX/M10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6PDM2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2550360|ensembl:ENSMUSP00000120595|uniprotkb:B2KGJ5|uniprotkb:Q3UCH2|uniprotkb:Q5SXC5|uniprotkb:Q8BJV3|uniprotkb:Q8C1H9 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srsf1_mouse(display_long)|uniprotkb:Sfrs1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym)|uniprotkb:Srsf1(gene name)|psi-mi:Srsf1(display_short)|uniprotkb:ASF/SF2(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRp30a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000018379(gene)|ensembl:ENSMUST00000139129(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0050733"(RS domain binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097398"(cellular response to interleukin-17)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:0110012"(protein localization to P-body)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q6PDM2|rcsb pdb:1X4C|go:"GO:0005654"(nucleoplasm)|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-72165|refseq:NP_001071635.1|refseq:NP_775550.2|dip:DIP-48723N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q922F4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2310445|ensembl:ENSMUSP00000001513 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tbb6_mouse(display_long)|uniprotkb:Tubb6(gene name)|psi-mi:Tubb6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_080749.2|ensembl:ENSMUSG00000001473(gene)|ensembl:ENSMUST00000001513(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q922F4|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:HJaJs+zsyUZjmGSYEmEbcln56Z410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O35295 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-647544|ensembl:ENSMUSP00000136957 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:purb_mouse(display_long)|uniprotkb:Purine-rich element-binding protein B(gene name synonym)|uniprotkb:Vascular actin single-stranded DNA-binding factor 2 p44 component(gene name synonym)|uniprotkb:Purb(gene name)|psi-mi:Purb(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000094483(gene)|ensembl:ENSMUST00000179343(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|refseq:NP_035351.1|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030499|mint:O35295 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ZeoADmerELfkQ00oZ1w7a+wgQeA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9EQU5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BFV2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170526|ensembl:ENSMUSP00000133204|uniprotkb:Q147Z6|uniprotkb:Q8C951 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pcid2_mouse(display_long)|uniprotkb:Pcid2(gene name)|psi-mi:Pcid2(display_short)|uniprotkb:CSN12-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000038542(gene)|ensembl:ENSMUST00000164416(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|refseq:NP_848823.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:SyT/2trRGDNBEooZNejTJFBjDaw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q62383 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1373250|uniprotkb:Q5SYM0|uniprotkb:Q6GQS3|uniprotkb:Q6ZQI0|uniprotkb:Q8BQY6|ensembl:ENSMUSP00000002121 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:spt6h_mouse(display_long)|uniprotkb:Supt6h(gene name)|psi-mi:Supt6h(display_short)|uniprotkb:Kiaa0162(gene name synonym)|uniprotkb:Supt6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033323.2|ensembl:ENSMUSG00000002052(gene)|ensembl:ENSMUST00000002121(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003677"(DNA binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045191"(regulation of isotype switching)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051028"(mRNA transport)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR000980(SH2 motif)|interpro:IPR003029(S1, RNA binding)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR022967|interpro:IPR023319|interpro:IPR023323|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR041692|interpro:IPR042066|mint:Q62383|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:h9yOnI51aroUlQNPlgQzPlOquJs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O54833 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1216452|ensembl:ENSMUSP00000055919|ensembl:ENSMUSP00000148404 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:csk22_mouse(display_long)|uniprotkb:Csnk2a2(gene name)|psi-mi:Csnk2a2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_034104.1|ensembl:ENSMUSG00000046707(gene)|ensembl:ENSMUST00000056919(transcript)|ensembl:ENSMUST00000212214(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031519"(PcG protein complex)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O54833|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6aE12BakwtzXfYRZ4EwCGSG5wBE10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P49962 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170507|ensembl:ENSMUSP00000027792|uniprotkb:Q9D085 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srp09_mouse(display_long)|uniprotkb:Srp9(gene name)|psi-mi:Srp9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000026511(gene)|ensembl:ENSMUST00000027792(transcript)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|rcsb pdb:1914|reactome:R-MMU-1799339|refseq:NP_036188.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6I3ZL6SAzV2hzWmBT4djOOA0ixA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q921F2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6876933|ensembl:ENSMUSP00000081142|uniprotkb:Q3U591|uniprotkb:Q3V0E7 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tadbp_mouse(display_long)|uniprotkb:Tardbp(gene name)|psi-mi:Tardbp(display_short)|uniprotkb:Tdp43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001003899.1|refseq:NP_001008545.1|refseq:NP_001008546.1|refseq:NP_001292354.1|ensembl:ENSMUSG00000041459(gene)|ensembl:ENSMUST00000084125(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q921F2|rcsb pdb:3D2W|refseq:NP_663531.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:j1U3NZd8O/lAclOPSRt10NY58e810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6XLQ8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170493|ensembl:ENSMUSP00000087967 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:q6xlq8_mouse(display_long)|uniprotkb:Calu(gene name)|psi-mi:Calu(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000029767(gene)|ensembl:ENSMUST00000090481(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:Q6XLQ8|refseq:NP_908942.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:iKkW8kLyVgMzA7Cc0rSxcDE0+jk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q7TMM9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2255578|ensembl:ENSMUSP00000060246 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tbb2a_mouse(display_long)|uniprotkb:Tubb2(gene name synonym)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033476.1|ensembl:ENSMUSG00000058672(gene)|ensembl:ENSMUST00000056427(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q7TMM9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O35887 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-688160|ensembl:ENSMUSP00000031779 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:calu_mouse(display_long)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:Calu(gene name)|psi-mi:Calu(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_031620.1|ensembl:ENSMUSG00000029767(gene)|ensembl:ENSMUST00000031779(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019899"(enzyme binding)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O35887|reactome:R-MMU-381426|reactome:R-MMU-8957275 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:JSG2x2O/Lpg1JYjpePi+aqwSx+g10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8JZM7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1216399|ensembl:ENSMUSP00000018337 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:cdc73_mouse(display_long)|uniprotkb:Cdc73(gene name)|psi-mi:Cdc73(display_short)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_666103.1|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q8JZM7|reactome:R-MMU-112382|reactome:R-MMU-201722|reactome:R-MMU-5632684|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|ensembl:ENSMUSG00000026361(gene)|ensembl:ENSMUST00000018337(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O35099 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-777493|uniprotkb:Q14AY5|ensembl:ENSMUSP00000093485 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:m3k5_mouse(display_long)|uniprotkb:MAPK/ERK kinase kinase 5(gene name synonym)|uniprotkb:Apoptosis signal-regulating kinase 1(gene name synonym)|uniprotkb:Map3k5(gene name)|psi-mi:Map3k5(display_short)|uniprotkb:Ask1(gene name synonym)|uniprotkb:Mekk5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_032606.4|dip:DIP-38055N|ensembl:ENSMUSG00000071369(gene)|ensembl:ENSMUST00000095806(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010941"(regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902170"(cellular response to reactive nitrogen species)|go:"GO:1902911"(protein kinase complex)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025136|interpro:IPR043969|mint:O35099|reactome:R-MMU-2559580 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:i1P8YtUNmpFauFUVVxzsMYoQYOw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q60855 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-529119|uniprotkb:Q3U0J3|uniprotkb:Q8CD90|ensembl:ENSMUSP00000021844|ensembl:ENSMUSP00000129831 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ripk1_mouse(display_long)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)|uniprotkb:Ripk1(gene name)|psi-mi:Ripk1(display_short)|uniprotkb:Rinp(gene name synonym)|uniprotkb:Rip(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033094.3|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0006954"(inflammatory response)|refseq:XP_006516670.1|refseq:XP_006516672.1|ensembl:ENSMUSG00000021408(gene)|ensembl:ENSMUST00000021844(transcript)|ensembl:ENSMUST00000167374(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|dip:DIP-34962N|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070513"(death domain binding)|go:"GO:0070926"("regulation of ATP:ADP antiporter activity")|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097342"(ripoptosome)|go:"GO:0097343"(ripoptosome assembly)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901026"(ripoptosome assembly involved in necroptotic process)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR025735|interpro:IPR037934|mint:Q60855|reactome:R-MMU-140534|reactome:R-MMU-2562578|reactome:R-MMU-3295583|reactome:R-MMU-3371378|reactome:R-MMU-5213460|reactome:R-MMU-5218900|reactome:R-MMU-5357786|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5675482|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-69416|reactome:R-MMU-75893|reactome:R-MMU-937041 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:GvihCfN74Xs5oEVwbSSzu/roj5A10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8R5H1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6909541|ensembl:ENSMUSP00000151244|uniprotkb:Q3TGF5|uniprotkb:Q3TTB2|uniprotkb:Q3UL25|uniprotkb:Q3UZH0|uniprotkb:Q80TY6|uniprotkb:Q80UK9 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ubp15_mouse(display_long)|uniprotkb:Usp15(gene name)|psi-mi:Usp15(display_short)|uniprotkb:Kiaa0529(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001288557.1|ensembl:ENSMUSG00000020124(gene)|ensembl:ENSMUST00000220377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q8R5H1|reactome:R-MMU-5689880|refseq:NP_081880.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:vvaDGXL6KpPnD9139IhT7RNCExs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BL97 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-913123|uniprotkb:Q8BMC6|uniprotkb:Q8BUR2|uniprotkb:Q8R2N4|uniprotkb:Q8R3E9|uniprotkb:Q91YS1 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srsf7_mouse(display_long)|uniprotkb:Srsf7(gene name)|psi-mi:Srsf7(display_short)|uniprotkb:Sfrs7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|reactome:R-MMU-73856|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72187|refseq:NP_001182414.1|refseq:NP_001182415.1|refseq:NP_001182416.1|refseq:NP_666195.1|refseq:XP_006524253.1|mint:Q8BL97|dip:DIP-36580N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:dgBF3NFB/dJM+SEsycw66i4Z86g10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P84104 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2550426|ensembl:ENSMUSP00000117045|uniprotkb:O08831|uniprotkb:P23152|uniprotkb:Q564E9 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srsf3_mouse(display_long)|uniprotkb:Sfrs3(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 3(gene name synonym)|uniprotkb:Srsf3(gene name)|psi-mi:Srsf3(display_short)|uniprotkb:Srp20(gene name synonym)|uniprotkb:X16(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRP20(gene name synonym)|uniprotkb:Protein X16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000071172(gene)|ensembl:ENSMUST00000130216(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P84104|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|refseq:NP_038691.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:BcfyCj2cNNTH1igANKpvh4IHDVU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VEJ1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170475|ensembl:ENSMUSP00000030661|uniprotkb:A2A9E9 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:gpn2_mouse(display_long)|uniprotkb:Gpn2(gene name)|psi-mi:Gpn2(display_short)|uniprotkb:Atpbd1b(gene name synonym)|uniprotkb:ATP-binding domain 1 family member B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000028848(gene)|ensembl:ENSMUST00000030661(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030231|refseq:NP_598645.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:U/SEbX3K0gbkoTwJzFRnl77yYuM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9WVJ9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170450|ensembl:ENSMUSP00000128827|ensembl:ENSMUSP00000133016 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:fbln4_mouse(display_long)|uniprotkb:Efemp2(gene name)|psi-mi:Efemp2(display_short)|uniprotkb:Fbln4(gene name synonym)|uniprotkb:Mbp1(gene name synonym)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Mutant p53-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000024909(gene)|ensembl:ENSMUST00000165485(transcript)|ensembl:ENSMUST00000166303(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0060840"(artery development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|reactome:R-MMU-2129379|refseq:NP_067449.3|refseq:XP_006531871.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:nd2kQjGuio52R3CAeqoQ0H233lM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BMJ3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170425|ensembl:ENSMUSP00000084387|uniprotkb:Q3UY50|uniprotkb:Q6ZWL8|uniprotkb:Q8BJZ2|uniprotkb:Q8BMH8|uniprotkb:Q9CSL9 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:if1ax_mouse(display_long)|uniprotkb:Eif1ax(gene name)|psi-mi:Eif1ax(display_short)|uniprotkb:Eif1ay(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000067194(gene)|ensembl:ENSMUST00000087143(transcript)|go:"GO:0003743"(translation initiation factor activity)|interpro:IPR001253("Eukaryotic initiation factor 1A (eIF-1A)")|interpro:IPR006196(S1, IF1 type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018104|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|refseq:NP_079713.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:C/YFiphF76YhqKYoM7ybw320ihw10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VCE2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170404|ensembl:ENSMUSP00000076217 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:gpn1_mouse(display_long)|uniprotkb:Gpn1(gene name)|psi-mi:Gpn1(display_short)|uniprotkb:Mbdin(gene name synonym)|uniprotkb:Xab1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000064037(gene)|ensembl:ENSMUST00000076949(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|refseq:NP_598517.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:QsNvVutIiDD20I99c65U1XUXy1g10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6PFR5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-913075 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tra2a_mouse(display_long)|uniprotkb:Transformer-2 protein homolog A(gene name synonym)|uniprotkb:Tra2a(gene name)|psi-mi:Tra2a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q6PFR5|interpro:IPR035979 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:sI1aKVOABu0cBLl+Nv3kORRqzcg10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CYP7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170378|ensembl:ENSMUSP00000146362|uniprotkb:Q3U2A0 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:sesn3_mouse(display_long)|uniprotkb:Sesn3(gene name)|psi-mi:Sesn3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000032009(gene)|ensembl:ENSMUST00000208222(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0032868"(response to insulin)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070728"(leucine binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:1901031"(regulation of response to reactive oxygen species)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR006730("PA26 p53-induced protein (sestrin)")|interpro:IPR029032|reactome:R-MMU-5628897|reactome:R-MMU-9639288|refseq:NP_084537.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:9pJdL336YRN8hffRXyu+EG8YTIA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9Z0P7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CWR2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170344|ensembl:ENSMUSP00000117410|uniprotkb:Q6P7V6|uniprotkb:Q8BG90 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:smyd3_mouse(display_long)|uniprotkb:Smyd3(gene name)|psi-mi:Smyd3(display_short)|uniprotkb:Zmynd1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000055067(gene)|ensembl:ENSMUST00000128302(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|reactome:R-MMU-3214841|refseq:NP_081464.1|refseq:XP_006497045.1|refseq:XP_017167700.1|refseq:XP_017167702.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:QTEnl1tnx0UmirLb4sS+2D/Vm0Q10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8C1Z8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170313|uniprotkb:Q4KMM8|uniprotkb:Q5CZW9|uniprotkb:Q8VDF5 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tm10a_mouse(display_long)|uniprotkb:Trmt10a(gene name)|psi-mi:Trmt10a(display_short)|uniprotkb:Rg9mtd2(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 2"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase TRMT10A"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0000049"(tRNA binding)|go:"GO:0002939"(tRNA N1-guanine methylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030488"(tRNA methylation)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0090646"(mitochondrial tRNA processing)|refseq:NP_001335125.1|refseq:NP_001335126.1|refseq:NP_780598.2|refseq:XP_006500909.1|refseq:XP_006500910.1|refseq:XP_011238285.1|interpro:IPR028564|interpro:IPR038459|interpro:IPR016653("tRNA (guanine-N(1)-)-methyltransferase, metazoa")|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|refseq:XP_006500906.1|refseq:XP_006500907.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:VMjnCNdcoSM0aMwvXazBgCBsiu810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BP92 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-642694|uniprotkb:O70341|uniprotkb:A2RT07|ensembl:ENSMUSP00000109915 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rcn2_mouse(display_long)|uniprotkb:Taipoxin-associated calcium-binding protein 49(gene name synonym)|uniprotkb:Rcn2(gene name)|psi-mi:Rcn2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_036122.2|ensembl:ENSMUSG00000032320(gene)|ensembl:ENSMUST00000114276(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8BP92|dip:DIP-46963N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:vsMMmWAPrlDNQDUxzH4wrp1Jub410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BNL5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170285|ensembl:ENSMUSP00000022272|ensembl:ENSMUSP00000129059|uniprotkb:Q3TXX1 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:kctd6_mouse(display_long)|uniprotkb:Kctd6(gene name)|psi-mi:Kctd6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000021752(gene)|ensembl:ENSMUST00000022272(transcript)|ensembl:ENSMUST00000170111(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_001292865.1|refseq:NP_001292866.1|refseq:NP_082058.1|refseq:XP_006518168.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:14FoiobU4n/dXBS9MH5Tgufu+q410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62806 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-299632|ensembl:ENSMUSP00000085006|ensembl:ENSMUSP00000100029|ensembl:ENSMUSP00000100030|ensembl:ENSMUSP00000100032|ensembl:ENSMUSP00000100033|ensembl:ENSMUSP00000100036|ensembl:ENSMUSP00000100037|ensembl:ENSMUSP00000100042|ensembl:ENSMUSP00000100044|ensembl:ENSMUSP00000100048|ensembl:ENSMUSP00000100546|ensembl:ENSMUSP00000129930|ensembl:ENSMUSP00000136357|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q2M2Q5|intact:EBI-302111|uniprotkb:Q6PDS7|uniprotkb:Q811M0|uniprotkb:A0AUM5|uniprotkb:A4FUP8|uniprotkb:A4QMY0|uniprotkb:Q0VDL9|uniprotkb:Q9D0C9|uniprotkb:Q9D6Q8|uniprotkb:Q5T006 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:h4_mouse(display_long)|uniprotkb:H4c11(gene name)|psi-mi:H4c11(display_short)|uniprotkb:H4c12(gene name)|psi-mi:H4c12(display_short)|uniprotkb:H4c14(gene name)|psi-mi:H4c14(display_short)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4c3(gene name)|psi-mi:H4c3(display_short)|uniprotkb:H4c4(gene name)|psi-mi:H4c4(display_short)|uniprotkb:H4c6(gene name)|psi-mi:H4c6(display_short)|uniprotkb:H4c8(gene name)|psi-mi:H4c8(display_short)|uniprotkb:H4c9(gene name)|psi-mi:H4c9(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist1h4a(gene name synonym)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist1h4c(gene name synonym)|uniprotkb:Hist1h4d(gene name synonym)|uniprotkb:Hist1h4f(gene name synonym)|uniprotkb:Hist1h4h(gene name synonym)|uniprotkb:Hist1h4i(gene name synonym)|uniprotkb:Hist1h4j(gene name synonym)|uniprotkb:Hist1h4k(gene name synonym)|uniprotkb:Hist2h4a(gene name synonym)|uniprotkb:Hist2h4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4-53(gene name synonym)|uniprotkb:H4-12(gene name synonym)|uniprotkb:H4c1(gene name)|psi-mi:H4c1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000060093(gene)|ensembl:ENSMUSG00000060639(gene)|ensembl:ENSMUSG00000060678(gene)|ensembl:ENSMUSG00000060981(gene)|ensembl:ENSMUSG00000061482(gene)|ensembl:ENSMUSG00000064288(gene)|ensembl:ENSMUSG00000067455(gene)|ensembl:ENSMUSG00000069266(gene)|ensembl:ENSMUSG00000069274(gene)|ensembl:ENSMUSG00000069305(gene)|ensembl:ENSMUSG00000069306(gene)|ensembl:ENSMUSG00000091405(gene)|ensembl:ENSMUST00000087714(transcript)|ensembl:ENSMUST00000102964(transcript)|ensembl:ENSMUST00000102965(transcript)|ensembl:ENSMUST00000102967(transcript)|ensembl:ENSMUST00000102968(transcript)|ensembl:ENSMUST00000102971(transcript)|ensembl:ENSMUST00000102972(transcript)|ensembl:ENSMUST00000102977(transcript)|ensembl:ENSMUST00000102979(transcript)|ensembl:ENSMUST00000102983(transcript)|ensembl:ENSMUST00000104941(transcript)|ensembl:ENSMUST00000171473(transcript)|ensembl:ENSMUST00000179285(transcript)|go:"GO:0000228"(nuclear chromosome)|ensembl:ENSMUSG00000096010(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62806|rcsb pdb:1F66|rcsb pdb:1U35|rcsb pdb:2WP2|go:"GO:0003677"(DNA binding)|rcsb pdb:4AU7|rcsb pdb:4DOW|rcsb pdb:5B1L|rcsb pdb:5B1M|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-110330|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214842|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-4551638|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|refseq:NP_001182350.1|refseq:NP_291074.1|refseq:NP_694813.1|refseq:NP_783583.1|refseq:NP_783585.1|refseq:NP_783586.1|refseq:NP_783587.1|refseq:NP_783588.1|refseq:NP_835499.1|refseq:NP_835500.1|refseq:NP_835515.1|refseq:NP_835582.1|refseq:NP_835583.1|dip:DIP-45837N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9QVP9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-299061|ensembl:ENSMUSP00000022622|ensembl:ENSMUSP00000137008|uniprotkb:B2RQ16|uniprotkb:G3X8V1 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:fak2_mouse(display_long)|uniprotkb:Pyk2(gene name synonym)|uniprotkb:Raftk(gene name synonym)|uniprotkb:Ptk2b(gene name)|psi-mi:Ptk2b(display_short)|uniprotkb:Fak2(gene name synonym)|uniprotkb:Focal adhesion kinase 2(gene name synonym)|uniprotkb:Proline-rich tyrosine kinase 2(gene name synonym)|uniprotkb:Cell adhesion kinase beta(gene name synonym)|uniprotkb:Calcium-dependent tyrosine kinase(gene name synonym)|uniprotkb:Related adhesion focal tyrosine kinase(gene name synonym)|uniprotkb:Calcium-regulated non-receptor proline-rich tyrosine kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000059456(gene)|ensembl:ENSMUST00000022622(transcript)|ensembl:ENSMUST00000178730(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001525"(angiogenesis)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006968"(cellular defense response)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009725"(response to hormone)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0010752"(regulation of cGMP-mediated signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032960"(regulation of inositol trisphosphate biosynthetic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043423"(3-phosphoinositide-dependent protein kinase binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051591"(response to cAMP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000538"(positive regulation of B cell chemotaxis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR029071|interpro:IPR030610|interpro:IPR035963|interpro:IPR036137|interpro:IPR041390|interpro:IPR041784|mint:Q9QVP9|reactome:R-MMU-391160|reactome:R-MMU-4420097|reactome:R-MMU-9020558|refseq:XP_006518789.1|refseq:XP_011243296.1|refseq:NP_001155838.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:wFolkPm20C8WJ9CP/rnhc2FxqT410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O35326 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-15757617|ensembl:ENSMUSP00000105981|ensembl:ENSMUSP00000105985|ensembl:ENSMUSP00000131323|uniprotkb:Q640L9 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srsf5_mouse(display_long)|uniprotkb:Srsf5(gene name)|psi-mi:Srsf5(display_short)|uniprotkb:Hrs(gene name synonym)|uniprotkb:Sfrs5(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000021134(gene)|ensembl:ENSMUST00000094693(transcript)|ensembl:ENSMUST00000110356(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0009611"(response to wounding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|reactome:R-MMU-159236|reactome:R-MMU-72163|ensembl:ENSMUST00000110352(transcript)|reactome:R-MMU-72187|reactome:R-MMU-73856|refseq:NP_001073162.1|refseq:NP_001073163.1|refseq:NP_033185.2|refseq:NP_001334345.1|dip:DIP-48724N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:V72CLm6HmZh0zeg3n1k0r3aCOD410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8CHG3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-643470|uniprotkb:Q8BR44|uniprotkb:Q8R2Q5|uniprotkb:Q9CT45 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:gcc2_mouse(display_long)|uniprotkb:185 kDa Golgi coiled-coil protein(gene name synonym)|uniprotkb:Gcc2(gene name)|psi-mi:Gcc2(display_short)|uniprotkb:Kiaa0336(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR000237(GRIP)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0016020"(membrane)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034499"(late endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0070861"(regulation of protein exit from endoplasmic reticulum)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR032023|reactome:R-MMU-6811440 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:jx7CHCvebJMJveYd27Mhq56/So010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D3W4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170265|ensembl:ENSMUSP00000031420|uniprotkb:Q8BU32 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:gpn3_mouse(display_long)|uniprotkb:Gpn3(gene name)|psi-mi:Gpn3(display_short)|uniprotkb:Atpbd1c(gene name synonym)|uniprotkb:D5Ertd708e(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000029464(gene)|ensembl:ENSMUST00000031420(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|refseq:NP_077178.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:gMSlGVRYGHvsJ1/3q7+GfzO1qSA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q3TWW8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-9989273|uniprotkb:Q3UJV5|uniprotkb:Q921K3|uniprotkb:Q9DBP1|ensembl:ENSMUSP00000119065 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:srsf6_mouse(display_long)|uniprotkb:Srsf6(gene name)|psi-mi:Srsf6(display_short)|uniprotkb:Sfrs6(gene name synonym)|uniprotkb:Srp55(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_080775.3|ensembl:ENSMUSG00000016921(gene)|ensembl:ENSMUST00000130411(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|reactome:R-MMU-159236|go:"GO:0003723"(RNA binding)|reactome:R-MMU-72165|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-72163 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:/l6R/Dpz2RgXmBU+qQerM46ZnRU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9Z199 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170243 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:spt4b_mouse(display_long)|uniprotkb:Supt4h1b(gene name)|psi-mi:Supt4h1b(display_short)|uniprotkb:Gm3258(gene name synonym)|uniprotkb:Supt4b(gene name synonym)|uniprotkb:Supt4h2(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor small subunit 2(gene name synonym)|uniprotkb:Transcription elongation factor SPT4 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0006325"(chromatin organization)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038510|refseq:NP_035639.1|interpro:IPR029040|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:uCQwDpgaEoj76v/F7l7pk7pMzGQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D2Y4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-5401970|uniprotkb:Q8CIJ5|ensembl:ENSMUSP00000055521 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:mlkl_mouse(display_long)|uniprotkb:Mlkl(gene name)|psi-mi:Mlkl(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_083281.1|refseq:NP_001297542.1|refseq:XP_006531505.1|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0097528"(execution phase of necroptosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036537|rcsb pdb:4BTF|rcsb pdb:4M68|rcsb pdb:4M69|reactome:R-MMU-3295583|reactome:R-MMU-5213460|reactome:R-MMU-5675482|ensembl:ENSMUSG00000012519(gene)|ensembl:ENSMUST00000056157(transcript)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070266"(necroptotic process) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:psAtDkJEqy995YtXIt+xgMVYHWI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O55229 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17170223|ensembl:ENSMUSP00000023289 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:chkb_mouse(display_long)|uniprotkb:Chkb(gene name)|psi-mi:Chkb(display_short)|uniprotkb:Chetk(gene name synonym)|uniprotkb:Chkl(gene name synonym)|uniprotkb:Choline kinase beta(gene name synonym)|uniprotkb:Ethanolamine kinase(gene name synonym)|uniprotkb:choline/ethanolamine kinase beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000022617(gene)|ensembl:ENSMUST00000023289(transcript)|go:"GO:0004103"(choline kinase activity)|go:"GO:0004305"(ethanolamine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007517"(muscle organ development)|interpro:IPR011009(Protein kinase-like)|interpro:IPR026712|reactome:R-MMU-1483191|reactome:R-MMU-1483213|refseq:NP_031718.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:N6iIrwcyGtV6udN1SOMfcqwK02g10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9EQH3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q7TSI3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4286465|uniprotkb:Q80TJ4|ensembl:ENSMUSP00000066736 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pp6r1_mouse(display_long)|uniprotkb:Ppp6r1(gene name)|psi-mi:Ppp6r1(display_short)|uniprotkb:Kiaa1115(gene name synonym)|uniprotkb:Pp6r1(gene name synonym)|uniprotkb:Saps1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_766482.2|refseq:XP_011248858.1|ensembl:ENSMUSG00000052296(gene)|ensembl:ENSMUST00000064099(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|reactome:R-MMU-204005 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ET7IE429eaRNAHpRwjds5XF7nrA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P40336 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-775981|uniprotkb:Q3TGY3|uniprotkb:Q3THM5|uniprotkb:Q3TW99|uniprotkb:Q3UD54|uniprotkb:Q8C1E9|ensembl:ENSMUSP00000101087 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vp26a_mouse(display_long)|uniprotkb:Vesicle protein sorting 26A(gene name synonym)|uniprotkb:H58 protein(gene name synonym)|uniprotkb:Vps26a(gene name)|psi-mi:Vps26a(display_short)|uniprotkb:Vps26(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001106826.1|refseq:NP_598433.1|dip:DIP-32041N|ensembl:ENSMUSG00000020078(gene)|ensembl:ENSMUST00000105447(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:P40336|rcsb pdb:4P2A|rcsb pdb:6VAC|reactome:R-MMU-3238698 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:fzT+kSNk6/aqTm7hSsSbItmgyYE10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P62826 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9DCH4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1634316|uniprotkb:Q5XJV3|ensembl:ENSMUSP00000033342 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3f_mouse(display_long)|uniprotkb:Eif3f(gene name)|psi-mi:Eif3f(display_short)|uniprotkb:Eif3s5(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_079620.2|dip:DIP-42766N|ensembl:ENSMUSG00000031029(gene)|ensembl:ENSMUST00000033342(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:Q9DCH4|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:RTpmhLHfvqVe3dkVb7fImMfdeTA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P68254 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-400675|uniprotkb:P35216|uniprotkb:Q3TW69|uniprotkb:Q3UJN5|uniprotkb:Q5SP76|uniprotkb:Q5U423|uniprotkb:Q66JR6|ensembl:ENSMUSP00000100067|ensembl:ENSMUSP00000123605 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:1433t_mouse(display_long)|uniprotkb:Ywhaq(gene name)|psi-mi:Ywhaq(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035869.1|ensembl:ENSMUSG00000076432(gene)|ensembl:ENSMUST00000103002(transcript)|ensembl:ENSMUST00000135088(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P68254|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9614399 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:l8bki6QJJEH5S5NIwQdm/MAYcc010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P49312 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-642826|uniprotkb:P97312|uniprotkb:Q3V269|ensembl:ENSMUSP00000084609|ensembl:ENSMUSP00000155833 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:roa1_mouse(display_long)|uniprotkb:Hnrpa1(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:HDP-1(gene name synonym)|uniprotkb:Single-strand-binding protein(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed(gene name synonym)|uniprotkb:Hnrnpa1(gene name)|psi-mi:Hnrnpa1(display_short)|uniprotkb:Fli-2(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_034577.1|ensembl:ENSMUSG00000046434(gene)|ensembl:ENSMUST00000087351(transcript)|ensembl:ENSMUST00000230171(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0035198"(miRNA binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P49312|go:"GO:0008380"(RNA splicing)|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Co5hW3ZlIoa2k56GA2/9RJBNguI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O54724 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-645496|uniprotkb:Q2TAW6|ensembl:ENSMUSP00000058321 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:cavn1_mouse(display_long)|uniprotkb:Cavin1(gene name)|psi-mi:Cavin1(display_short)|uniprotkb:Cav-p60(gene name synonym)|uniprotkb:Cavin-1(gene name synonym)|uniprotkb:Polymerase I and transcript release factor(gene name synonym)|uniprotkb:Ptrf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033012.1|dip:DIP-40506N|ensembl:ENSMUSG00000004044(gene)|ensembl:ENSMUST00000060792(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009306"(protein secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR026752|interpro:IPR033297|mint:O54724|rcsb pdb:4QKV|reactome:R-MMU-73863|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:hPJHFyrpyl5yz+7Brojuu3W2bEA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P60122 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1634999|uniprotkb:O35753|ensembl:ENSMUSP00000032165 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ruvb1_mouse(display_long)|uniprotkb:Ruvbl1(gene name)|psi-mi:Ruvbl1(display_short)|uniprotkb:Tip49(gene name synonym)|uniprotkb:Tip49a(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:DNA helicase p50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_062659.1|ensembl:ENSMUSG00000030079(gene)|ensembl:ENSMUST00000032165(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:P60122|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5696394|reactome:R-MMU-606279 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:fZiQ7AurvKII0LYc+haBswAXfZ410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P14901 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-299000|ensembl:ENSMUSP00000005548 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hmox1_mouse(display_long)|uniprotkb:Hmox1(gene name)|psi-mi:Hmox1(display_short)|uniprotkb:P32 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0002246"(wound healing involved in inflammatory response)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006788"(heme oxidation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0034395"(regulation of transcription from RNA polymerase II promoter in response to iron)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042167"(heme catabolic process)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0043627"(response to estrogen)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097421"(liver regeneration)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P14901|reactome:R-MMU-189483|reactome:R-MMU-917937|reactome:R-MMU-9609523|reactome:R-MMU-9707564|reactome:R-MMU-9707587|ensembl:ENSMUSG00000005413(gene)|ensembl:ENSMUST00000005548(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|refseq:NP_034572.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:UqAfpYwWVllusAkONxCAZKyU0zQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D0M5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-767129|uniprotkb:A7M7R8|uniprotkb:Q3TFB4|ensembl:ENSMUSP00000020775|ensembl:ENSMUSP00000103556|ensembl:ENSMUSP00000136241 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dyl2_mouse(display_long)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym)|uniprotkb:Dynll2(gene name)|psi-mi:Dynll2(display_short)|uniprotkb:Dlc2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001161943.1|refseq:NP_001161944.1|refseq:NP_080832.1|ensembl:ENSMUSG00000020483(gene)|ensembl:ENSMUST00000020775(transcript)|ensembl:ENSMUST00000107923(transcript)|ensembl:ENSMUST00000178105(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q9D0M5|rcsb pdb:1RE6|reactome:R-MMU-139910|reactome:R-MMU-141444|reactome:R-MMU-1632852|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-5620924|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-9646399|reactome:R-MMU-9648025 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:4RFpJF40RBja5mOvt/aCv3miiDU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9WTX5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1202363|uniprotkb:Q8C5H6|ensembl:ENSMUSP00000038744|ensembl:ENSMUSP00000104700 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:skp1_mouse(display_long)|uniprotkb:Skp1(gene name)|psi-mi:Skp1(display_short)|uniprotkb:Skp1a(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035673.3|refseq:XP_006532849.1|go:"GO:0019904"(protein domain specific binding)|ensembl:ENSMUSG00000036309(gene)|ensembl:ENSMUST00000037324(transcript)|ensembl:ENSMUST00000109072(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:Q9WTX5|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168|dip:DIP-38596N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:qGk720KMKAbBPguy2tmUOZsLxRQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O70194 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-773893|uniprotkb:Q8BLH0|uniprotkb:Q8BWW1|ensembl:ENSMUSP00000098053 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3d_mouse(display_long)|uniprotkb:Eif3s7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym)|uniprotkb:Eif3d(gene name)|psi-mi:Eif3d(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_061219.2|refseq:XP_006521255.1|ensembl:ENSMUSG00000016554(gene)|ensembl:ENSMUST00000100484(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O70194|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:3AScEAsTKzZ+lSa6oU8pPy6UxgM10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P10630 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1634890|uniprotkb:Q61513|uniprotkb:Q61514|ensembl:ENSMUSP00000023599 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:if4a2_mouse(display_long)|uniprotkb:Eif4a2(gene name)|psi-mi:Eif4a2(display_short)|uniprotkb:Ddx2b(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001116509.1|refseq:NP_001116510.1|refseq:NP_038534.2|refseq:NP_001334108.1|ensembl:ENSMUSG00000022884(gene)|ensembl:ENSMUST00000023599(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900260"(negative regulation of RNA-directed 5'-3' RNA polymerase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P10630|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-429947|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:m9i/jWfsbU+6kQvj1h06x31+awg10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q80X95 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-10061024|uniprotkb:B1AXR0|uniprotkb:Q8C1S2|uniprotkb:Q8CFU3|ensembl:ENSMUSP00000088591 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rraga_mouse(display_long)|uniprotkb:Rraga(gene name)|psi-mi:Rraga(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_848463.1|ensembl:ENSMUSG00000070934(gene)|ensembl:ENSMUST00000091064(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042268"(regulation of cytolysis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903432"(regulation of TORC1 signaling)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990130"(GATOR1 complex)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8866654|reactome:R-MMU-8943724|reactome:R-MMU-9639288 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:1BxTVycwXop9+lViwQU5TyK/tlI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O88544 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-646659|ensembl:ENSMUSP00000048416 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:csn4_mouse(display_long)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym)|uniprotkb:Cops4(gene name)|psi-mi:Cops4(display_short)|uniprotkb:Csn4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_036131.1|ensembl:ENSMUSG00000035297(gene)|ensembl:ENSMUST00000045993(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:O88544|rcsb pdb:1UFM|reactome:R-MMU-5696394|reactome:R-MMU-6781823|reactome:R-MMU-8856825|reactome:R-MMU-8951664|reactome:R-MMU-9013422 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:oD7xaeBArd5bKxdEAWM/r+5KMb010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q1H9T6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-11104272|uniprotkb:A2A8B1|uniprotkb:Q99K15|ensembl:ENSMUSP00000067521 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tzap_mouse(display_long)|uniprotkb:Zbtb48(gene name)|psi-mi:Zbtb48(display_short)|uniprotkb:Hkr3(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein 3 homolog(gene name synonym)|uniprotkb:Tzap(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_598640.2|ensembl:ENSMUSG00000028952(gene)|ensembl:ENSMUST00000066715(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2DLQ|rcsb pdb:2YY9 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:pdshzPQ1o3vJ3TkzVKPi21ek23A10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P61965 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1247084|uniprotkb:Q91VA5|uniprotkb:Q922C9|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|ensembl:ENSMUSP00000109585 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:wdr5_mouse(display_long)|uniprotkb:Wdr5(gene name)|psi-mi:Wdr5(display_short)|uniprotkb:Big(gene name synonym)|uniprotkb:Big3(gene name synonym)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WD repeat-containing protein BIG-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_543124.1|refseq:XP_006497735.1|dip:DIP-38618N|ensembl:ENSMUSG00000026917(gene)|ensembl:ENSMUST00000113952(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61965|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-3214841|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-8936459|reactome:R-MMU-8951664 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CYA6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-5738935|uniprotkb:Q3TK71|uniprotkb:Q8CCB7|uniprotkb:Q91WQ1|ensembl:ENSMUSP00000031376|ensembl:ENSMUSP00000142363 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:zchc8_mouse(display_long)|uniprotkb:Zcchc8(gene name)|psi-mi:Zcchc8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_081770.3|ensembl:ENSMUSG00000029427(gene)|ensembl:ENSMUST00000031376(transcript)|ensembl:ENSMUST00000196282(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034470"(ncRNA processing)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR006568(PSP, proline-rich)|mint:Q9CYA6 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:wDsSWQ3jCutZRCk3H7jQnasAkyk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9WVP9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17171201|ensembl:ENSMUSP00000024112|uniprotkb:Q922L4 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:mx2_mouse(display_long)|uniprotkb:Myxovirus resistance protein 2(gene name synonym)|uniprotkb:Mx2(gene name)|psi-mi:Mx2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000023341(gene)|ensembl:ENSMUST00000024112(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|reactome:R-MMU-1169408|refseq:NP_038634.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:gSG3NwvSn+kVK9H5WXBPLLZA4do10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9DBC7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-645677|uniprotkb:Q3UKU7|uniprotkb:Q9JHR5|uniprotkb:Q9JHR6|ensembl:ENSMUSP00000056500|ensembl:ENSMUSP00000102288 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:kap0_mouse(display_long)|uniprotkb:Prkar1a(gene name)|psi-mi:Prkar1a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001300902.1|refseq:NP_001300903.1|refseq:NP_001300904.1|refseq:NP_001300905.1|refseq:NP_068680.1|refseq:XP_017169829.1|dip:DIP-32450N|ensembl:ENSMUSG00000020612(gene)|ensembl:ENSMUST00000049527(transcript)|ensembl:ENSMUST00000106677(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007507"(heart development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|reactome:R-MMU-983231|reactome:R-MMU-5610787|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:Q9DBC7|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-432040|go:"GO:0043949"(regulation of cAMP-mediated signaling)|reactome:R-MMU-442720 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:0KqlQxZjK8QfS6VPEiTDtvHNTj410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q922D4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4286373|uniprotkb:Q6ZPM9|uniprotkb:Q8BTW6|uniprotkb:Q9D2X9|ensembl:ENSMUSP00000025846 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pp6r3_mouse(display_long)|uniprotkb:Ppp6r3(gene name)|psi-mi:Ppp6r3(display_short)|uniprotkb:D19Ertd703e(gene name synonym)|uniprotkb:Kiaa1558(gene name synonym)|uniprotkb:Pp6r3(gene name synonym)|uniprotkb:Saps3(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001157631.1|refseq:NP_083275.1|refseq:NP_083732.1|ensembl:ENSMUSG00000024908(gene)|ensembl:ENSMUST00000025846(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q922D4|reactome:R-MMU-171319|reactome:R-MMU-204005|refseq:XP_006531859.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:cfyYAB9Ybqu8fRU64DNvVMI6zOE10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P36916 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17171182|ensembl:ENSMUSP00000084450|uniprotkb:E9QPZ9|uniprotkb:Q91Z20 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:gnl1_mouse(display_long)|uniprotkb:GTP-binding protein MMR1(gene name synonym)|uniprotkb:Gnl1(gene name)|psi-mi:Gnl1(display_short)|uniprotkb:Gna-rs1(gene name synonym)|uniprotkb:Mmr1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000024429(gene)|ensembl:ENSMUST00000087200(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006974"(cellular response to DNA damage stimulus)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358|mint:P36916|refseq:NP_032162.2 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:5GvOQdadvg4RmdDORomaCEW+7cc10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9WUK4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1180276|ensembl:ENSMUSP00000023867 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rfc2_mouse(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Rfc2(gene name)|psi-mi:Rfc2(display_short)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_064406.1|ensembl:ENSMUSG00000023104(gene)|ensembl:ENSMUST00000023867(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-174411|reactome:R-MMU-176187|reactome:R-MMU-5651801|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693616|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6804756|reactome:R-MMU-69091|reactome:R-MMU-69473|reactome:R-MMU-5693607 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:2j8wh6ZmnhZRPxiT9YkzZzfQXME10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P23116 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2552342|uniprotkb:E9QQ50|ensembl:ENSMUSP00000025955|uniprotkb:Q62162|uniprotkb:Q60697 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3a_mouse(display_long)|uniprotkb:Eif3a(gene name)|psi-mi:Eif3a(display_short)|uniprotkb:Csma(gene name synonym)|uniprotkb:Eif3(gene name synonym)|uniprotkb:Eif3s10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)|uniprotkb:p162(gene name synonym)|uniprotkb:Centrosomin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000024991(gene)|ensembl:ENSMUST00000025955(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:P23116|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|go:"GO:0014069"(postsynaptic density)|refseq:NP_034253.3 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:oL2Xlz5tghN0YkjvCd3nXOj15Hk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q80UW8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6094615|ensembl:ENSMUSP00000004786 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rpab1_mouse(display_long)|uniprotkb:Polr2e(gene name)|psi-mi:Polr2e(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_079830.2|ensembl:ENSMUSG00000004667(gene)|ensembl:ENSMUST00000004786(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|reactome:R-MMU-77075|reactome:R-MMU-9018519 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:NKA6+5grFwQn41K1TqXFHmmyXcs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q78PY7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-529864|uniprotkb:Q3TT46|uniprotkb:Q922L5|uniprotkb:Q9R0S1|ensembl:ENSMUSP00000001460 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:snd1_mouse(display_long)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:Snd1(gene name)|psi-mi:Snd1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_062750.2|dip:DIP-32118N|ensembl:ENSMUSG00000001424(gene)|ensembl:ENSMUST00000001460(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q78PY7|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold") - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:cqMQzuPhE4OOYZg5AuBiYjoHYjI10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q61166 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2027055|uniprotkb:Q7TN34|ensembl:ENSMUSP00000028981 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:mare1_mouse(display_long)|uniprotkb:Mapre1(gene name)|psi-mi:Mapre1(display_short)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_031922.1|dip:DIP-46795N|ensembl:ENSMUSG00000027479(gene)|ensembl:ENSMUST00000028981(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q61166|rcsb pdb:1V5K|rcsb pdb:6EVI|rcsb pdb:6EVQ|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-9648025 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:HQQfAZTgxRU4kb8LGRRwKkDpLx810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8R3Q2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4285597|uniprotkb:Q9CXB7 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pp6r2_mouse(display_long)|uniprotkb:Ppp6r2(gene name)|psi-mi:Ppp6r2(display_short)|uniprotkb:Kiaa0685(gene name synonym)|uniprotkb:Pp6r2(gene name synonym)|uniprotkb:Saps2(gene name synonym)|uniprotkb:SAPS domain family member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 mint:Q8R3Q2|interpro:IPR007587(SIT4 phosphatase-associated protein)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR016024(Armadillo-type fold) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:NKhCFgctjoEdJxqAxzU6GnXg4iQ10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BFR5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-299611|ensembl:ENSMUSP00000095656|uniprotkb:Q497E7|uniprotkb:Q6P919 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eftu_mouse(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000073838(gene)|ensembl:ENSMUST00000098048(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:Q8BFR5|go:"GO:0042645"(mitochondrial nucleoid)|refseq:NP_001157185.1|refseq:NP_766333.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ax4f72KkJMxjxZD3ZClHh/oby3k10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P17156 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-494667|intact:EBI-2942789|uniprotkb:Q99KD7|ensembl:ENSMUSP00000079306|ensembl:ENSMUSP00000151408 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hsp72_mouse(display_long)|uniprotkb:Hspa2(gene name)|psi-mi:Hspa2(display_short)|uniprotkb:Hcp70.2(gene name synonym)|uniprotkb:Hsp70-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001002012.1|refseq:NP_032327.2|refseq:XP_006515547.1|dip:DIP-42071N|ensembl:ENSMUSG00000059970(gene)|ensembl:ENSMUST00000080449(transcript)|ensembl:ENSMUST00000219555(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-MMU-3371568|go:"GO:0005739"(mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|go:"GO:0007286"(spermatid development)|interpro:IPR029048|interpro:IPR043129|reactome:R-MMU-3371453|reactome:R-MMU-3371497 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:wpWle7NX8ixNNq35mZt14enug4E10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P57784 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6877081|ensembl:ENSMUSP00000117947|uniprotkb:Q3U7R8|uniprotkb:Q8K2W4|uniprotkb:Q91YW1|uniprotkb:Q9JKQ3 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ru2a_mouse(display_long)|uniprotkb:Snrpa1(gene name)|psi-mi:Snrpa1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000030512(gene)|ensembl:ENSMUST00000153609(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR044640|mint:P57784|reactome:R-MMU-72163|refseq:NP_067311.4 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:AMQnbw028+3/guP4MfrfDJCFu6s10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VHN7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17171120|uniprotkb:Q6ZQ69|uniprotkb:Q810D2|uniprotkb:Q810D3|uniprotkb:Q91ZS0|uniprotkb:Q91ZS1 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:agrv1_mouse(display_long)|uniprotkb:Adgrv1(gene name)|psi-mi:Adgrv1(display_short)|uniprotkb:G-protein coupled receptor 98(gene name synonym)|uniprotkb:Gpr98(gene name synonym)|uniprotkb:Kiaa0686(gene name synonym)|uniprotkb:Mass1(gene name synonym)|uniprotkb:Monogenic audiogenic seizure susceptibility protein 1(gene name synonym)|uniprotkb:Neurepin(gene name synonym)|uniprotkb:Very large G-protein coupled receptor 1(gene name synonym)|uniprotkb:Vlgr1(gene name synonym)|uniprotkb:Protein rueda(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002141"(stereocilia ankle link)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009986"(cell surface)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010855"(adenylate cyclase inhibitor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017022"(myosin binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0043235"(receptor complex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0048839"(inner ear development)|go:"GO:0050877"(nervous system process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0097264"(self proteolysis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:1990696"(USH2 complex)|interpro:IPR038081|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR009039(EAR)|interpro:IPR005492(EPTP)|interpro:IPR017981|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR026919|interpro:IPR000203(GPS)|interpro:IPR006558(LamG-like jellyroll fold) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:fgVsOcm+0hF2lKoWHxDmmr3YKSs10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P63037 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-772408|uniprotkb:P54102|ensembl:ENSMUSP00000030118|ensembl:ENSMUSP00000129730 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dnja1_mouse(display_long)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:Dnaja1(gene name)|psi-mi:Dnaja1(display_short)|uniprotkb:Dnaj2(gene name synonym)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Hspf4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001158143.1|refseq:NP_001158144.1|refseq:NP_032324.1|dip:DIP-32350N|ensembl:ENSMUSG00000028410(gene)|ensembl:ENSMUST00000030118(transcript)|ensembl:ENSMUST00000164233(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P63037|reactome:R-MMU-3371497 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:gi42F7LF6CiylXZF4fRg/kuM/s010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8R5L3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2527842|uniprotkb:Q922I3|ensembl:ENSMUSP00000099559 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vps39_mouse(display_long)|uniprotkb:Vps39(gene name)|psi-mi:Vps39(display_short)|uniprotkb:Pldn(gene name synonym)|uniprotkb:Vam6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000027291(gene)|ensembl:ENSMUST00000102501(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001180(Citron-like)|interpro:IPR019452|interpro:IPR019453|interpro:IPR032914|refseq:NP_671495.1|refseq:NP_849182.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:u32ysqx9VEB8AuKHZPeszm16Cy410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D0E1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-773789|uniprotkb:Q6P1B2|uniprotkb:Q99JQ0|ensembl:ENSMUSP00000120115 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hnrpm_mouse(display_long)|uniprotkb:Hnrpm(gene name synonym)|uniprotkb:Hnrnpm(gene name)|psi-mi:Hnrnpm(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001103383.1|refseq:NP_084080.1|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904591"(positive regulation of protein import)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:Q9D0E1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000059208(gene)|ensembl:ENSMUST00000148178(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0048306"(calcium-dependent protein binding) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:VpoWJwPx1uDzAsBxM3/TfiCMGok10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8R307 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2527788|uniprotkb:Q8BGV6|uniprotkb:Q8BZX6|uniprotkb:Q8C126|ensembl:ENSMUSP00000036915 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:vps18_mouse(display_long)|uniprotkb:Vps18(gene name)|psi-mi:Vps18(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000034216(gene)|ensembl:ENSMUST00000037280(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)|refseq:NP_758473.3 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ZYg55QUg3B3pBixwuFUqaAsB+W410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:D3Z3N4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-11517461|ensembl:ENSMUSP00000020263 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:d3z3n4_mouse(display_long)|uniprotkb:Hnrnph3(gene name)|psi-mi:Hnrnph3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001073293.1|refseq:XP_006513900.1|refseq:XP_006513901.1|ensembl:ENSMUSG00000020069(gene)|ensembl:ENSMUST00000020263(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:0005634"(nucleus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:D3Z3N4 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Te+IJ76PZRXSgcY4YRpeaCE/Sjo10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q02257 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1751183|uniprotkb:Q8CGD3|intact:EBI-4280673|ensembl:ENSMUSP00000001592|ensembl:ENSMUSP00000103026 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:plak_mouse(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_034723.1|refseq:XP_006532378.1|refseq:XP_006532379.1|ensembl:ENSMUSG00000001552(gene)|ensembl:ENSMUST00000001592(transcript)|ensembl:ENSMUST00000107403(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:Q02257|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:vGVqOkILXpeS3KOS5oPBztoWuts10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6ZQ88 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1216284|ensembl:ENSMUSP00000111977|uniprotkb:Q6PB53|uniprotkb:Q8VEA1|uniprotkb:A3KG94 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:kdm1a_mouse(display_long)|uniprotkb:Kdm1a(gene name)|psi-mi:Kdm1a(display_short)|uniprotkb:Kiaa0601(gene name synonym)|uniprotkb:Lsd1(gene name synonym)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:Aof2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_598633.2|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0032991"(protein-containing complex)|ensembl:ENSMUSG00000036940(gene)|ensembl:ENSMUST00000116273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008134"(transcription factor binding)|dip:DIP-38599N|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034649"("obsolete histone demethylase activity (H3-monomethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046098"(guanine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0055001"(muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903827"|go:"GO:1990138"(neuron projection extension)|go:"GO:1990391"(DNA repair complex)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017366(Histone lysine-specific demethylase)|interpro:IPR036188|mint:Q6ZQ88|reactome:R-MMU-3214815|reactome:R-MMU-3214842|reactome:R-MMU-5625886|reactome:R-MMU-9018519|reactome:R-MMU-983231|interpro:IPR036388 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:4rlXgUzLs3mhV2FLX207Io9etU010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O08553 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q61990 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-644300|uniprotkb:Q61383|uniprotkb:Q62042|ensembl:ENSMUSP00000076294|ensembl:ENSMUSP00000077509 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pcbp2_mouse(display_long)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Putative heterogeneous nuclear ribonucleoprotein X(gene name synonym)|uniprotkb:CTBP(gene name synonym)|uniprotkb:Pcbp2(gene name)|psi-mi:Pcbp2(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Hnrnpx(gene name synonym)|uniprotkb:Hnrpx(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001096635.1|refseq:NP_001096636.1|refseq:NP_035172.2|ensembl:ENSMUST00000077037(transcript)|ensembl:ENSMUST00000078404(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1990829"(C-rich single-stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q61990|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000056851(gene) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:yU+DhZ+Fk16mrIjcAU4S2ttCOxo10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q3U1J4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2552275|ensembl:ENSMUSP00000025649|uniprotkb:Q99LV3|uniprotkb:Q9QYK0|uniprotkb:Q3U8G3|uniprotkb:Q9WV39|uniprotkb:Q3UJC4|uniprotkb:Q3U4D0 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ddb1_mouse(display_long)|uniprotkb:Ddb1(gene name)|psi-mi:Ddb1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000024740(gene)|ensembl:ENSMUST00000025649(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_056550.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|mint:Q3U1J4|reactome:R-MMU-110314|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|go:"GO:0005654"(nucleoplasm)|dip:DIP-56812N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:dvNwCrG9In1FV2j/+PrsSMvqFnk10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:E9Q557 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-688046|ensembl:ENSMUSP00000115062 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273 - - comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)" figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q80XI4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17171091|ensembl:ENSMUSP00000018691|uniprotkb:Q8VHB2 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pi42b_mouse(display_long)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-beta(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-beta(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II beta(gene name synonym)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-beta"(gene name synonym)|uniprotkb:Pip4k2b(gene name)|psi-mi:Pip4k2b(display_short)|uniprotkb:Pip5k2b(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000018547(gene)|ensembl:ENSMUST00000018691(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|reactome:R-MMU-1660499|reactome:R-MMU-6811555|reactome:R-MMU-6811558|reactome:R-MMU-8847453|refseq:NP_473392.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:55/FF0JicSSIAY3daFu0/LyRdY410090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q61656 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-643076|uniprotkb:E9Q105 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ddx5_mouse(display_long)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD1(gene name synonym)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Tnz2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-MMU-3899300|reactome:R-MMU-72163|reactome:R-MMU-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|dip:DIP-32293N|mint:Q61656 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:X5OQN/Gdq852njTrHnlDliAjrQY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8JZQ9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4286513|uniprotkb:Q922K2|ensembl:ENSMUSP00000098076 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eif3b_mouse(display_long)|uniprotkb:Eif3b(gene name)|psi-mi:Eif3b(display_short)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:Eif3s9(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_598677.1|ensembl:ENSMUSG00000056076(gene)|ensembl:ENSMUST00000100507(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045202"(synapse)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:Q8JZQ9|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Mi9GReY+V693P20QOUsHizsl5DY10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9DCR2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-9085419|uniprotkb:O88670|ensembl:ENSMUSP00000025357 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ap3s1_mouse(display_long)|uniprotkb:Ap3s1(gene name)|psi-mi:Ap3s1(display_short)|uniprotkb:AP-3 complex subunit sigma-3A(gene name synonym)|uniprotkb:Sigma-3A-adaptin(gene name synonym)|uniprotkb:Sigma-adaptin 3a(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit sigma-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033811.1|ensembl:ENSMUSG00000024480(gene)|ensembl:ENSMUST00000025357(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027155|reactome:R-MMU-432722|go:"GO:0048490"(anterograde synaptic vesicle transport) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:fRNNY4ETqt4Qv6CTQqFxeIk8Syc10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P60843 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6665935|ensembl:ENSMUSP00000127034|uniprotkb:P04765|uniprotkb:Q61516 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:if4a1_mouse(display_long)|uniprotkb:Eif4a1(gene name)|psi-mi:Eif4a1(display_short)|uniprotkb:Ddx2a(gene name synonym)|uniprotkb:Eif4a(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000059796(gene)|ensembl:ENSMUST00000163666(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60843|rcsb pdb:6XKI|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-429947|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706|refseq:NP_659207.1 - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q05144 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-642680|uniprotkb:Q3TBC4|uniprotkb:Q9D8X9|ensembl:ENSMUSP00000036384 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rac2_mouse(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Protein EN-7(gene name synonym)|uniprotkb:Rac2(gene name)|psi-mi:Rac2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033034.1|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q05144|reactome:R-MMU-114604|reactome:R-MMU-1222556|reactome:R-MMU-1257604|reactome:R-MMU-4086400|reactome:R-MMU-5668599|reactome:R-MMU-6811558|reactome:R-MMU-9013404|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSMUSG00000033220(gene)|ensembl:ENSMUST00000043214(transcript)|dip:DIP-41834N - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:e+jv1gu9ydUEvBgplFcRQ6APjw810090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q60953 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-3895605|uniprotkb:Q8CEJ1|uniprotkb:Q8VCC4|ensembl:ENSMUSP00000082816 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pml_mouse(display_long)|uniprotkb:Pml(gene name)|psi-mi:Pml(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17171503|imex:IM-26378-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_032910.3|refseq:NP_835188.2|dip:DIP-29279N|refseq:NP_001298017.1|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR021978|mint:Q60953|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-6804758|reactome:R-MMU-8934593|reactome:R-MMU-8948747|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|ensembl:ENSMUSG00000036986(gene)|ensembl:ENSMUST00000085673(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding) - - - figure legend:figure 1B, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:A1IYoBcjvvc01u8zfXWPo7ANLSo10090 rigid:oPVys8oNTrR2HrhRgj67qrb0e8c false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9WVH9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-7465688|intact:MINT-4094993|uniprotkb:Q541Z7|ensembl:ENSMUSP00000021603 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:fbln5_mouse(display_long)|uniprotkb:Fbln5(gene name)|psi-mi:Fbln5(display_short)|uniprotkb:Dance(gene name synonym)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035942.1|ensembl:ENSMUSG00000021186(gene)|ensembl:ENSMUST00000021603(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046903"(secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098867"(intramembranous bone growth)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR037288|mint:Q9WVH9|reactome:R-MMU-1566948|reactome:R-MMU-2129379 - - function:Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling|comment:mint figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:qSEP5mtYIyyHhSVNnG0DkIirMUc10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O70250 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8345874|intact:MINT-4107290|ensembl:ENSMUSP00000020768 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pgam2_mouse(display_long)|uniprotkb:Pgam2(gene name)|psi-mi:Pgam2(display_short)|uniprotkb:BPG-dependent PGAM 2(gene name synonym)|uniprotkb:Muscle-specific phosphoglycerate mutase(gene name synonym)|uniprotkb:Phosphoglycerate mutase isozyme M(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_061358.1|ensembl:ENSMUSG00000020475(gene)|ensembl:ENSMUST00000020768(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046538"(2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity)|go:"GO:0046689"(response to mercury ion)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:O70250|reactome:R-MMU-70171|reactome:R-MMU-70263 - - function:"Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity"|comment:mint figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:PdyQZ9OxuBEXxrCLBx7C/GYPvp010090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D7M1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8312972|ensembl:ENSMUSP00000029090|ensembl:ENSMUSP00000077753|intact:MINT-4092378 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:gid8_mouse(display_long)|uniprotkb:Gid8(gene name)|psi-mi:Gid8(display_short)|uniprotkb:Two hybrid-associated protein 1 with RanBPM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000027573(gene)|ensembl:ENSMUST00000029090(transcript)|ensembl:ENSMUST00000078687(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|mint:Q9D7M1|refseq:NP_083883.1|refseq:NP_001276580.1|refseq:NP_001276581.1 - - comment:mint figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:EEh4EgsBSQM3JfVheYmWB56VKnw10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8R3N6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8339876|uniprotkb:Q8BXY3|uniprotkb:Q8BWD5|intact:MINT-4137684|ensembl:ENSMUSP00000025137 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:thoc1_mouse(display_long)|uniprotkb:Thoc1(gene name)|psi-mi:Thoc1(display_short)|uniprotkb:Hpr1(gene name synonym)|uniprotkb:Nuclear matrix protein p84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_705780.1|ensembl:ENSMUSG00000024287(gene)|ensembl:ENSMUST00000025137(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048297"(negative regulation of isotype switching to IgA isotypes)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR021861|mint:Q8R3N6|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856 - - function:The THO/TREX complex is recruited to transcribed genes and travels with the RNA polymerase during elongation. It may physically link proteins that function in transcription and in RNA export|comment:mint figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Uz/HUphb7mFTNFZnJXumoC7r32010090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BKT7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8341251|intact:MINT-4111331|uniprotkb:Q8CHR3|uniprotkb:Q69ZU0 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:thoc5_mouse(display_long)|uniprotkb:Thoc5(gene name)|psi-mi:Thoc5(display_short)|uniprotkb:Fmip(gene name synonym)|uniprotkb:Kiaa0983(gene name synonym)|uniprotkb:Fms-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_766026.1|interpro:IPR019163|mint:Q8BKT7|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001824"(blastocyst development)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0017145"(stem cell division)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000035"(regulation of stem cell division)|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856 - - function:May be involved in the differentiation of granulocytes and adipocytes|comment:mint figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:2BPGcX+Efvb2o67V17No87ke2rM10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6NZJ6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8175606|uniprotkb:Q6NZN8|uniprotkb:Q8BW99|intact:MINT-1856450|ensembl:ENSMUSP00000047678|ensembl:ENSMUSP00000111120 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:if4g1_mouse(display_long)|uniprotkb:Eif4g1(gene name)|psi-mi:Eif4g1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001291361.1|refseq:NP_666053.2|refseq:XP_006522000.1|dip:DIP-42771N|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|reactome:R-MMU-975957|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q6NZJ6|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-450408|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|ensembl:ENSMUSG00000045983(gene)|ensembl:ENSMUST00000044783(transcript)|ensembl:ENSMUST00000115460(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process) - - comment:mint|function:Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:91tJB28zzWTM77Jg0kZ18KIUhmo10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9CQH8 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8585991|ensembl:ENSMUSP00000023924|intact:UNK-5539939 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rpp14_mouse(display_long)|uniprotkb:Rpp14(gene name)|psi-mi:Rpp14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000023156(gene)|ensembl:ENSMUST00000023924(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005730"(nucleolus)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR038085|refseq:NP_080214.1|refseq:XP_006518153.1|refseq:XP_006518154.1 - - comment:mint|function:Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:k9yRHHZPBx4ZIPAms5cQeMvLSUs10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9EQQ9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8321615|uniprotkb:Q8BK05|intact:MINT-2844950|uniprotkb:Q9CUR7|uniprotkb:Q6ZQ71|uniprotkb:Q8CFX2|uniprotkb:Q3ULY7|uniprotkb:Q8BTT2|uniprotkb:Q9CSJ4|ensembl:ENSMUSP00000026243 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:oga_mouse(display_long)|uniprotkb:Oga(gene name)|psi-mi:Oga(display_short)|uniprotkb:Beta-N-acetylhexosaminidase(gene name synonym)|uniprotkb:Beta-hexosaminidase(gene name synonym)|uniprotkb:Bifunctional protein NCOAT(gene name synonym)|uniprotkb:Hexc(gene name synonym)|uniprotkb:Kiaa0679(gene name synonym)|uniprotkb:Meningioma-expressed antigen 5(gene name synonym)|uniprotkb:Mgea5(gene name synonym)|uniprotkb:N-acetyl-beta-D-glucosaminidase(gene name synonym)|uniprotkb:N-acetyl-beta-glucosaminidase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_076288.1|ensembl:ENSMUSG00000025220(gene)|ensembl:ENSMUST00000026243(transcript)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006044"(N-acetylglucosamine metabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010616"(negative regulation of cardiac muscle adaptation)|go:"GO:0016231"(beta-N-acetylglucosaminidase activity)|go:"GO:0031343"(positive regulation of cell killing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046060"(dATP metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0051054"(positive regulation of DNA metabolic process)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060051"(negative regulation of protein glycosylation)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0070265"(necrotic cell death)|go:"GO:0102166"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity")|go:"GO:0102167"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity")|go:"GO:0102571"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity")|interpro:IPR011496(Hyaluronidase eukaryotic/prokaryotic)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|mint:Q9EQQ9 - - comment:mint|function:"Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity (By similarity). Acetylates 'Lys-8' of histone H4" figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:QoVXkyUs7cUp4tG7pVJ7Sz2vMEM10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q7TMY4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8340269|uniprotkb:Q80VT4|intact:MINT-4124784|uniprotkb:Q3UIA6|uniprotkb:Q9CQ50|ensembl:ENSMUSP00000065819 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:thoc7_mouse(display_long)|uniprotkb:Thoc7(gene name)|psi-mi:Thoc7(display_short)|uniprotkb:Nif3l1bp1(gene name synonym)|uniprotkb:Ngg1-interacting factor 3-like protein 1-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001272709.1|refseq:NP_079711.1|ensembl:ENSMUSG00000053453(gene)|ensembl:ENSMUST00000065865(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR008501(Protein of unknown function DUF783)|mint:Q7TMY4|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856 - - comment:mint figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:3UtTcx+bM9GhFs7wEszmdWTvGFw10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8K337 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8392483|ensembl:ENSMUSP00000092375|intact:MINT-4105144|uniprotkb:Q91ZF8|uniprotkb:O54996|uniprotkb:Q8CF65 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:i5p2_mouse(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short)|uniprotkb:Inositol polyphosphate-5-phosphatase B(gene name synonym)|uniprotkb:Phosphoinositide 5-phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000028894(gene)|ensembl:ENSMUST00000094782(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0070613"(regulation of protein processing)|interpro:IPR000198(RhoGAP)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR031896|interpro:IPR036691|interpro:IPR037793|mint:Q8K337|rcsb pdb:2KIG|reactome:R-MMU-1855183|reactome:R-MMU-1855204|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_032411.3 - - comment:mint figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VE80 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8337951|uniprotkb:Q9CWI8|intact:MINT-4137709|ensembl:ENSMUSP00000026990 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:thoc3_mouse(display_long)|uniprotkb:Thoc3(gene name)|psi-mi:Thoc3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_082873.2|ensembl:ENSMUSG00000025872(gene)|ensembl:ENSMUST00000026990(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|interpro:IPR040132|mint:Q8VE80|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856 - - function:The THO/TREX complex is recruited to transcribed genes and travels with the RNA polymerase during elongation. It may physically link proteins that function in transcription and in RNA export|comment:mint figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:f39XOseDnnlIzhWE90wr+/gYsm810090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9JLI6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8317751|intact:MINT-4130305|uniprotkb:Q8CB94|uniprotkb:Q8CB57|intact:UNK-5971267 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:scly_mouse(display_long)|uniprotkb:Scly(gene name)|psi-mi:Scly(display_short)|uniprotkb:Scl(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR016454(Cysteine desulphurase, NifS)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|refseq:NP_057926.2|mint:Q9JLI6|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|go:"GO:0001887"(selenium compound metabolic process)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009000"(selenocysteine lyase activity)|go:"GO:0016261"(selenocysteine catabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070279"(vitamin B6 binding)|go:"GO:1900408"(negative regulation of cellular response to oxidative stress)|go:"GO:1902494"(catalytic complex)|reactome:R-MMU-2408508 - - comment:mint|function:Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:4bfxTe3f7NlnnFsEKmiL/4Zd24Y10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O88796 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8459162|intact:MINT-4132955|ensembl:ENSMUSP00000025714 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rpp30_mouse(display_long)|uniprotkb:Rpp30(gene name)|psi-mi:Rpp30(display_short)|uniprotkb:Rnasep2(gene name synonym)|uniprotkb:RNase P subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_062301.3|ensembl:ENSMUSG00000024800(gene)|ensembl:ENSMUST00000025714(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:O88796|reactome:R-MMU-6791226 - - comment:mint|function:Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:qANO2qyNO6bx6Sj3ieBH17GUxZ810090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P22907 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8321919|intact:MINT-4097350|uniprotkb:Q3TIV0|ensembl:ENSMUSP00000076575 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hem3_mouse(display_long)|uniprotkb:Hmbs(gene name)|psi-mi:Hmbs(display_short)|uniprotkb:Uros1(gene name synonym)|uniprotkb:Pre-uroporphyrinogen synthase(gene name synonym)|uniprotkb:Hydroxymethylbilane synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_038579.2|ensembl:ENSMUSG00000032126(gene)|ensembl:ENSMUST00000077353(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004418"(hydroxymethylbilane synthase activity)|go:"GO:0004852"(uroporphyrinogen-III synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006778"(porphyrin-containing compound metabolic process)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0018160"(peptidyl-pyrromethane cofactor linkage)|go:"GO:0030424"(axon)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0033014"(tetrapyrrole biosynthetic process)|go:"GO:0042493"|go:"GO:0043176"(amine binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000860(Tetrapyrrole biosynthesis, hydroxymethylbilane synthase)|interpro:IPR022417|interpro:IPR022418|interpro:IPR022419|interpro:IPR036803|mint:P22907|reactome:R-MMU-189451 - - comment:mint|function:Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:vn2nkrOKUsrRLdP5f5BaXWKbIL010090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q99KQ4 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-8316571|ensembl:ENSMUSP00000020886|uniprotkb:Q8C3B5|uniprotkb:Q9JKM0|intact:MINT-4123932 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:nampt_mouse(display_long)|uniprotkb:Nampt(gene name)|psi-mi:Nampt(display_short)|uniprotkb:Pbef1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1 homolog(gene name synonym)|uniprotkb:Visfatin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000020572(gene)|ensembl:ENSMUST00000020886(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:Q99KQ4|rcsb pdb:2GVL|rcsb pdb:2H3B|rcsb pdb:2H3D|reactome:R-MMU-197264|refseq:NP_067499.2|dip:DIP-29217N - - comment:mint|function:Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:skRuq0lO53/e2q8+4nPgLyO5YkQ10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9R0L7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-4285401 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:akp8l_mouse(display_long)|uniprotkb:Akap8l(gene name)|psi-mi:Akap8l(display_short)|uniprotkb:Nakap(gene name synonym)|uniprotkb:Nakap95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 interpro:IPR034736|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|mint:Q9R0L7 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:k4vqjb0Ct+MAwtLNb4HzGRodDtI10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P16381 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-773139|ensembl:ENSMUSP00000035261 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ddx3l_mouse(display_long)|uniprotkb:D1Pas1(gene name)|psi-mi:D1Pas1(display_short)|uniprotkb:Pl10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_149068.1|ensembl:ENSMUSG00000039224(gene)|ensembl:ENSMUST00000045108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:8oOwLE3GJgEG16k1LZwqP8TmLqU10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P07310 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-299493|ensembl:ENSMUSP00000146972 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:kcrm_mouse(display_long)|uniprotkb:Ckm(gene name)|psi-mi:Ckm(display_short)|uniprotkb:Ckmm(gene name synonym)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000030399(gene)|ensembl:ENSMUST00000208710(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006603"(phosphocreatine metabolic process)|go:"GO:0009408"(response to heat)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P07310|reactome:R-MMU-71288|refseq:NP_031736.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:HUwtOLpKEeqrxa326Rz+yjZ6/Mo10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q75N62 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172332|ensembl:ENSMUSP00000145255|ensembl:ENSMUSP00000145286|uniprotkb:Q3UZ12 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:gima8_mouse(display_long)|uniprotkb:Gimap8(gene name)|psi-mi:Gimap8(display_short)|uniprotkb:Ian9(gene name synonym)|uniprotkb:Imap8(gene name synonym)|uniprotkb:Immune-associated nucleotide-binding protein 9(gene name synonym)|uniprotkb:Immunity-associated protein 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000064262(gene)|ensembl:ENSMUST00000203083(transcript)|ensembl:ENSMUST00000203509(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0070232"(regulation of T cell apoptotic process)|interpro:IPR006703(AIG1)|interpro:IPR027417|refseq:NP_001070878.1|refseq:NP_997651.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:BeciVXeNamT7GKdeZ77RGVu/HoQ10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8CEC0 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2553822|uniprotkb:Q80Z13|uniprotkb:Q8K090|ensembl:ENSMUSP00000048101 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:nup88_mouse(display_long)|uniprotkb:Nup88(gene name)|psi-mi:Nup88(display_short)|uniprotkb:Nucleoporin Nup88(gene name synonym)|uniprotkb:88 kDa nucleoporin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001076800.1|refseq:NP_765982.2|ensembl:ENSMUSG00000040667(gene)|ensembl:ENSMUST00000035283(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|interpro:IPR019321|interpro:IPR037700|mint:Q8CEC0|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|go:"GO:0000278"(mitotic cell cycle)|refseq:NP_001263335.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:QwnD9umRMrvYXsXq4TRnnMLrrwI10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9ERU9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-643756|uniprotkb:E9QM01|uniprotkb:Q61992|uniprotkb:Q8C9K9|ensembl:ENSMUSP00000003310 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rbp2_mouse(display_long)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Ranbp2(gene name)|psi-mi:Ranbp2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_035370.2|reactome:R-MMU-191859|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|ensembl:ENSMUSG00000003226(gene)|ensembl:ENSMUST00000003310(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|mint:Q9ERU9|reactome:R-MMU-141444|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:cjIAIF0uuxSMRXErJiJc+OBJpAw10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:F7BPW6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172314|ensembl:ENSMUSP00000122255 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:f7bpw6_mouse(display_long)|uniprotkb:Sec16a(gene name)|psi-mi:Sec16a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000026924(gene)|ensembl:ENSMUST00000156442(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:sUDY0ItpiG4k/jZ0mfJFlW3calc10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:E9PYH6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172269|ensembl:ENSMUSP00000037600|ensembl:ENSMUSP00000047672 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:set1a_mouse(display_long)|uniprotkb:SET domain-containing protein 1A(gene name synonym)|uniprotkb:Setd1a(gene name)|psi-mi:Setd1a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000042308(gene)|ensembl:ENSMUST00000047075(transcript)|ensembl:ENSMUST00000047157(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0048096"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034467|interpro:IPR035979|interpro:IPR037841|interpro:IPR044570|reactome:R-MMU-3214841|reactome:R-MMU-8936459|go:"GO:0035097"(histone methyltransferase complex)|refseq:NP_821172.2|refseq:XP_017177700.1|refseq:XP_017177701.1|refseq:XP_017177702.1|refseq:XP_017177703.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:vNh5u0JJkgYRFxgpRqRYG4AMxFE10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q505F5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2255533|uniprotkb:Q3U380|uniprotkb:Q6ZPW2|uniprotkb:Q9CUZ0|ensembl:ENSMUSP00000030894 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:lrc47_mouse(display_long)|uniprotkb:Kiaa1185(gene name synonym)|uniprotkb:Lrrc47(gene name)|psi-mi:Lrrc47(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_957678.1|ensembl:ENSMUSG00000029028(gene)|ensembl:ENSMUST00000030894(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR020825|interpro:IPR032675|mint:Q505F5 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:rPKKMiAYd+Dtcvc0CJAMiCDhF/E10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9WUA3 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-642245|uniprotkb:Q3TNA9|uniprotkb:Q3U4P1|uniprotkb:Q3U7G4|uniprotkb:Q4KUG1|uniprotkb:Q543K8|uniprotkb:Q8C5I6|uniprotkb:Q9JI86|ensembl:ENSMUSP00000117030 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pfkap_mouse(display_long)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:Pfkp(gene name)|psi-mi:Pfkp(display_short)|uniprotkb:Pfkc(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_062677.1|ensembl:ENSMUSG00000021196(gene)|ensembl:ENSMUST00000138703(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q9WUA3|reactome:R-MMU-70171|go:"GO:0042802"(identical protein binding)|refseq:NP_001278000.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Dz8hYnA4o2kETOSclerHtt7l/b810090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 intact:EBI-17172254 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 - psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:f8vq88_mouse(display_short)|psi-mi:EBI-17172254(display_long)|uniprotkb:Gm5145(gene name)|psi-mi:Gm5145(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 uniprotkb:F8VQ88(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6lUVHyKFTkmrKpFjyxNAi6MqieE10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q64337 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-645025|uniprotkb:Q99JM8|ensembl:ENSMUSP00000099835 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:sqstm_mouse(display_long)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:STONE14(gene name synonym)|uniprotkb:Sqstm1(gene name)|psi-mi:Sqstm1(display_short)|uniprotkb:A170(gene name synonym)|uniprotkb:STAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001277698.1|refseq:NP_035148.1|ensembl:ENSMUSG00000015837(gene)|ensembl:ENSMUST00000102774(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR033741|interpro:IPR034866|interpro:IPR043145|mint:Q64337|rcsb pdb:2RRU|rcsb pdb:2ZJD|rcsb pdb:3ADE|rcsb pdb:3B0F|rcsb pdb:3WDZ|reactome:R-MMU-205043|reactome:R-MMU-209543|reactome:R-MMU-209560|reactome:R-MMU-5205685|reactome:R-MMU-9020702|reactome:R-MMU-9664873|dip:DIP-38490N - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:/BktZPkmiLsU1fKVqPSQ8ae2+SY10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P18654 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-397744|ensembl:ENSMUSP00000033671|uniprotkb:Q03140|uniprotkb:Q8K3J8|uniprotkb:B1AXN4 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ks6a3_mouse(display_long)|uniprotkb:Rps6ka3(gene name)|psi-mi:Rps6ka3(display_short)|uniprotkb:Rps6ka-rs1(gene name synonym)|uniprotkb:Rsk2(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 3(gene name synonym)|uniprotkb:Mapkapk1b(gene name synonym)|uniprotkb:Ribosomal S6 kinase 2(gene name synonym)|uniprotkb:pp90RSK2(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1b(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000031309(gene)|ensembl:ENSMUST00000033671(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041905|interpro:IPR041906|mint:P18654|rcsb pdb:2QR7|rcsb pdb:2QR8|rcsb pdb:3G51|rcsb pdb:3UBD|rcsb pdb:4EL9|rcsb pdb:4GUE|rcsb pdb:4M8T|rcsb pdb:4MAO|rcsb pdb:5O1S|reactome:R-MMU-198753|reactome:R-MMU-199920|reactome:R-MMU-2559582|reactome:R-MMU-442742|reactome:R-MMU-444257|reactome:R-MMU-881907|refseq:NP_683747.1|dip:DIP-31554N - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:5h7ZnIO/ZD+MvfouRrhQzWM3Q0010090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P84089 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2551866|ensembl:ENSMUSP00000021559|ensembl:ENSMUSP00000147411|uniprotkb:Q14259|uniprotkb:P70659 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:erh_mouse(display_long)|uniprotkb:Erh(gene name)|psi-mi:Erh(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000021131(gene)|ensembl:ENSMUSG00000063412(gene)|ensembl:ENSMUST00000021559(transcript)|ensembl:ENSMUST00000080152(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84089|rcsb pdb:1WWQ|rcsb pdb:1WZ7|refseq:NP_031977.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P83940 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2323027|uniprotkb:Q63182|ensembl:ENSMUSP00000111009|ensembl:ENSMUSP00000139675|ensembl:ENSMUSP00000140422|ensembl:ENSMUSP00000140962 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:eloc_mouse(display_long)|uniprotkb:Eloc(gene name)|psi-mi:Eloc(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:Stromal membrane-associated protein SMAP1B homolog(gene name synonym)|uniprotkb:Tceb1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_080732.1|refseq:NP_001297399.1|refseq:XP_006495624.1|refseq:XP_006495625.1|refseq:XP_006495626.1|refseq:XP_006495627.1|dip:DIP-42814N|ensembl:ENSMUSG00000079658(gene)|ensembl:ENSMUST00000115352(transcript)|ensembl:ENSMUST00000185771(transcript)|ensembl:ENSMUST00000186948(transcript)|ensembl:ENSMUST00000188641(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030891"(VCB complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:P83940|rcsb pdb:2FNJ|rcsb pdb:2JZ3|rcsb pdb:4JGH|reactome:R-MMU-112382|reactome:R-MMU-1234176|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-75955|reactome:R-MMU-8951664|reactome:R-MMU-9705462|reactome:R-MMU-983168 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz410090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8CI94 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-773709|uniprotkb:Q8K283|ensembl:ENSMUSP00000035743 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pygb_mouse(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_722476.1|ensembl:ENSMUSG00000033059(gene)|ensembl:ENSMUST00000045441(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q8CI94|reactome:R-MMU-6798695 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:sX820CE/XNwY/LEnJx/j4IF44Lk10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q4VAA2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172236|ensembl:ENSMUSP00000044420|uniprotkb:Q6P6L7|uniprotkb:Q920C7|uniprotkb:Q920I4 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:cdv3_mouse(display_long)|uniprotkb:Cdv3(gene name)|psi-mi:Cdv3(display_short)|uniprotkb:Carnitine deficiency-associated protein 3(gene name synonym)|uniprotkb:Tyrosine-phosphorylated protein 36(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000032803(gene)|ensembl:ENSMUST00000035484(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR026806|refseq:NP_780774.1|refseq:NP_787027.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:J/cCqVFUAD9ER2XBwOUed+xK69k10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q5M956 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172215|uniprotkb:Q5EER9 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:kctd1_mouse(display_long)|uniprotkb:Kctd1(gene name)|psi-mi:Kctd1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|refseq:NP_598873.2|refseq:XP_006525548.1|reactome:R-MMU-8866904|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation) - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:mv4g8/+TuoNkCitdTYpsxJH52I010090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8R5G7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-621463|ensembl:ENSMUSP00000035662|uniprotkb:E9QMK7|uniprotkb:Q5DTN4|uniprotkb:Q6NVF1|uniprotkb:Q8R5G6 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:arap3_mouse(display_long)|uniprotkb:Arap3(gene name)|psi-mi:Arap3(display_short)|uniprotkb:Dual specificity Rho- and Arf-GTPase-activating protein 1(gene name synonym)|uniprotkb:Centd3(gene name synonym)|uniprotkb:Centaurin-delta-3(gene name synonym)|uniprotkb:Drag1(gene name synonym)|uniprotkb:Kiaa4097(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000024451(gene)|ensembl:ENSMUST00000042944(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029071|interpro:IPR037278|interpro:IPR037858|interpro:IPR038508|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013423|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|refseq:NP_001192265.1|refseq:NP_631945.2|refseq:XP_006525552.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:T6pzqRyYhNTPo62IU2JQcqE0rQk10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:B1AZI6 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-11518070|ensembl:ENSMUSP00000044677 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:thoc2_mouse(display_long)|uniprotkb:Thoc2(gene name)|psi-mi:Thoc2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001028594.1|ensembl:ENSMUSG00000037475(gene)|ensembl:ENSMUST00000047037(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017145"(stem cell division)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048666"(neuron development)|go:"GO:0048699"(generation of neurons)|interpro:IPR021418|interpro:IPR021726|go:"GO:0003729"(mRNA binding)|interpro:IPR032302|interpro:IPR040007|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:vf+nmdCqLR+zGo4kClflRR0eIwk10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8VH37 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172173|ensembl:ENSMUSP00000085226|uniprotkb:Q3V270|uniprotkb:Q9D0K6 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hdac8_mouse(display_long)|uniprotkb:Hdac8(gene name)|psi-mi:Hdac8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000067567(gene)|ensembl:ENSMUST00000087916(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019213"(deacetylase activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903496"(response to 11-deoxycorticosterone)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:2000616"(negative regulation of histone H3-K9 acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3214815|reactome:R-MMU-350054|refseq:NP_001300671.1|refseq:NP_081658.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:h/3rwfWdU9agfyNhK8FJ5Cmf0bM10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9DB28 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172149|ensembl:ENSMUSP00000080215|ensembl:ENSMUSP00000118408|uniprotkb:Q9CSC3|uniprotkb:Q9CSL4 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:pop5_mouse(display_long)|uniprotkb:Pop5(gene name)|psi-mi:Pop5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR016819(Ribonuclease P/MRP protein, subunit Pop5)|interpro:IPR038085|ensembl:ENSMUSG00000060152(gene)|ensembl:ENSMUST00000081497(transcript)|ensembl:ENSMUST00000135455(transcript)|go:"GO:0000171"(ribonuclease MRP activity)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|refseq:NP_080674.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:lUQH+sMvwBeLosaWxrxRgMLvTq410090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P63166 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-80152|uniprotkb:P55856|uniprotkb:Q3TX92|uniprotkb:Q93068|ensembl:ENSMUSP00000088935 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:sumo1_mouse(display_long)|uniprotkb:Sumo1(gene name)|psi-mi:Sumo1(display_short)|uniprotkb:Smt3c(gene name synonym)|uniprotkb:Smt3h3(gene name synonym)|uniprotkb:Ubl1(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_033486.1|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-69473|reactome:R-MMU-877312|reactome:R-MMU-8866904|reactome:R-MMU-9615933|ensembl:ENSMUSG00000026021(gene)|ensembl:ENSMUST00000091374(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030578"(PML body organization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0001741"(XY body)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045202"(synapse)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|reactome:R-MMU-3065676|reactome:R-MMU-3065678|reactome:R-MMU-3065679|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|reactome:R-MMU-4615885|reactome:R-MMU-4655427|dip:DIP-29278N - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:O08583 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-6464301|ensembl:ENSMUSP00000026125|uniprotkb:Q0VBL5|uniprotkb:Q8CBM4|uniprotkb:Q9JJW7 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:thoc4_mouse(display_long)|uniprotkb:Alyref(gene name)|psi-mi:Alyref(display_short)|uniprotkb:Aly(gene name synonym)|uniprotkb:Ref1(gene name synonym)|uniprotkb:Refbp1(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:REF1-I(gene name synonym)|uniprotkb:RNA and export factor-binding protein 1(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000025134(gene)|ensembl:ENSMUST00000026125(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0051028"(mRNA transport)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025715|interpro:IPR035979|mint:O08583|rcsb pdb:1NO8|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|refseq:NP_035698.1|dip:DIP-59977N - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:DZAvcQrp7S1uipKsc/Wpxgb+gJI10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q5U4D9 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1216467|ensembl:ENSMUSP00000038137|ensembl:ENSMUSP00000093239|ensembl:ENSMUSP00000111153 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:thoc6_mouse(display_long)|uniprotkb:Thoc6(gene name)|psi-mi:Thoc6(display_short)|uniprotkb:Wdr58(gene name synonym)|uniprotkb:WD repeat-containing protein 58(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001008425.1|refseq:XP_006524607.1|ensembl:ENSMUSG00000041319(gene)|ensembl:ENSMUST00000047436(transcript)|ensembl:ENSMUST00000095579(transcript)|ensembl:ENSMUST00000115490(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR042626|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:6y4QY1KVfg2G46AzmVpqV2V+yIQ10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9JMA2 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172126|ensembl:ENSMUSP00000002902|uniprotkb:Q80VS3 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:tgt_mouse(display_long)|uniprotkb:Qtrt1(gene name)|psi-mi:Qtrt1(display_short)|uniprotkb:Tgt(gene name synonym)|uniprotkb:Tgut(gene name synonym)|uniprotkb:Guanine insertion enzyme(gene name synonym)|uniprotkb:tRNA-guanine transglycosylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000002825(gene)|ensembl:ENSMUST00000002902(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006400"(tRNA modification)|go:"GO:0008479"(queuine tRNA-ribosyltransferase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0101030"(tRNA-guanine transglycosylation)|interpro:IPR002616(Queuine/other tRNA-ribosyltransferase)|interpro:IPR004803(Queuine tRNA-ribosyltransferase)|interpro:IPR036511|rcsb pdb:6H62|refseq:NP_068688.2 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ev72+tA1Pt0qhv7I7HoVWgM5yRg10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q69ZJ7 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172096|uniprotkb:A4GZ02|uniprotkb:Q3U0Q6|uniprotkb:Q3UWK1 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ric1_mouse(display_long)|uniprotkb:Ric1(gene name)|psi-mi:Ric1(display_short)|uniprotkb:Kiaa1432(gene name synonym)|uniprotkb:Protein RIC1 homolog(gene name synonym)|uniprotkb:RAB6A-GEF complex partner protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 reactome:R-MMU-6811438|reactome:R-MMU-6811440|reactome:R-MMU-8876198|go:"GO:0000139"(Golgi membrane)|go:"GO:0003330"(regulation of extracellular matrix constituent secretion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR009771(Protein of unknown function DUF1339)|interpro:IPR040096 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:MAJ+T5OnQ8BAjpbg7lN69Kx7UHg10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q60973 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-302297|ensembl:ENSMUSP00000033720|uniprotkb:Q3UX20|uniprotkb:A2AFJ0 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:rbbp7_mouse(display_long)|uniprotkb:Rbbp7(gene name)|psi-mi:Rbbp7(display_short)|uniprotkb:Rbap46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q60973|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-606279|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-8951664|reactome:R-MMU-8953750|ensembl:ENSMUSG00000031353(gene)|ensembl:ENSMUST00000033720(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_033057.3|dip:DIP-32856N - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:+OV9hWS13A8fAypZJAXf656Z25U10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q8BY71 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-2657967|ensembl:ENSMUSP00000028408 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:hat1_mouse(display_long)|uniprotkb:Hat1(gene name)|psi-mi:Hat1(display_short)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_080391.2|ensembl:ENSMUSG00000027018(gene)|ensembl:ENSMUST00000028408(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|reactome:R-MMU-3214847|go:"GO:0005739"(mitochondrion) - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:5qGzSmbZX85IkAq65CYnMV+inpc10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q6P5C5 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172069|uniprotkb:Q9DBV1|ensembl:ENSMUSP00000065835|ensembl:ENSMUSP00000155594|ensembl:ENSMUSP00000155700 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:smug1_mouse(display_long)|uniprotkb:Smug1(gene name)|psi-mi:Smug1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_082161.2|refseq:XP_006521478.1|refseq:XP_011244033.1|refseq:XP_011244034.1|refseq:XP_011244035.1|refseq:XP_017172241.1|ensembl:ENSMUSG00000036061(gene)|ensembl:ENSMUST00000064067(transcript)|ensembl:ENSMUST00000229371(transcript)|ensembl:ENSMUST00000229377(transcript)|go:"GO:0000702"(oxidized base lesion DNA N-glycosylase activity)|go:"GO:0000703"(oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0017065"(single-strand selective uracil DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR036895|interpro:IPR039134|reactome:R-MMU-110329|reactome:R-MMU-110357 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:+8LWTV3uaCvaZ2GmkpN15sjwqio10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P46061 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-1033051|uniprotkb:Q60801|uniprotkb:Q6NZB5|ensembl:ENSMUSP00000057771|ensembl:ENSMUSP00000126849|ensembl:ENSMUSP00000130046 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ragp1_mouse(display_long)|uniprotkb:Rangap1(gene name)|psi-mi:Rangap1(display_short)|uniprotkb:Fug1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001139646.1|refseq:NP_035371.4|ensembl:ENSMUSG00000022391(gene)|ensembl:ENSMUST00000052374(transcript)|ensembl:ENSMUST00000170134(transcript)|ensembl:ENSMUST00000171115(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46061|rcsb pdb:1KPS|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108232|reactome:R-MMU-4615885|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9615933|reactome:R-MMU-9648025|dip:DIP-17024N - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:XrJlIJ7cGqaUyNGBsK1ifk0YbmU10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:B8ZXI1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17172047|uniprotkb:A9C446|uniprotkb:Q5XK35 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:qtrt2_mouse(display_long)|uniprotkb:Qtrt2(gene name)|psi-mi:Qtrt2(display_short)|uniprotkb:Qtrtd1(gene name synonym)|uniprotkb:Queuine tRNA-ribosyltransferase domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_083404.2|interpro:IPR028592|interpro:IPR036511|interpro:IPR002616(Queuine/other tRNA-ribosyltransferase)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008479"(queuine tRNA-ribosyltransferase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0101030"(tRNA-guanine transglycosylation)|rcsb pdb:6FV5|refseq:XP_006521731.1|refseq:XP_006521733.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:ypVNsU45Xf/IGYqTpJNeCUmY6u010090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:P63280 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-80180|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q6RUT3|uniprotkb:Q86VB3|ensembl:ENSMUSP00000055714|ensembl:ENSMUSP00000134169|ensembl:ENSMUSP00000134261|ensembl:ENSMUSP00000134350|ensembl:ENSMUSP00000134450|ensembl:ENSMUSP00000134491 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:ubc9_mouse(display_long)|uniprotkb:Ube2i(gene name)|psi-mi:Ube2i(display_short)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:Ubce9(gene name synonym)|uniprotkb:Ubce2i(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 refseq:NP_001171080.1|refseq:NP_001171081.1|refseq:NP_035795.1|ensembl:ENSMUSG00000015120(gene)|ensembl:ENSMUST00000049911(transcript)|ensembl:ENSMUST00000172618(transcript)|ensembl:ENSMUST00000173084(transcript)|ensembl:ENSMUST00000173713(transcript)|ensembl:ENSMUST00000174001(transcript)|ensembl:ENSMUST00000174031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990234"(transferase complex)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63280|rcsb pdb:1U9A|rcsb pdb:1U9B|rcsb pdb:2UYZ|rcsb pdb:2VRR|reactome:R-MMU-196791|reactome:R-MMU-3065678|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-4655427|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-8866904|reactome:R-MMU-9615933|refseq:XP_006524111.1|refseq:XP_006524112.1|dip:DIP-29276N - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9EPK7 uniprotkb:Q9D8X1 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 intact:EBI-17171231|ensembl:ENSMUSP00000107678 psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:cutc_mouse(display_long)|uniprotkb:Cutc(gene name)|psi-mi:Cutc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172030|imex:IM-26378-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 ensembl:ENSMUSG00000025193(gene)|ensembl:ENSMUST00000112047(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0051262"(protein tetramerization)|go:"GO:0055070"(copper ion homeostasis)|interpro:IPR005627(CutC)|interpro:IPR023648|interpro:IPR036822|refseq:NP_001107034.1 - - - figure legend:figure 1B-2, Supp file 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rogid:AyBRtx+cCSBLnDNYCgg2YQSmxgY10090 rigid:ir5githLil+zlym4IfKGzXKFA7k false his tag:?-?|protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07960 uniprotkb:P62826 intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172410|imex:IM-26378-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004299.1|refseq:XP_011518397.1|dip:DIP-6081N|ensembl:ENSG00000175220(gene)|ensembl:ENST00000311956(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696270 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2A-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:ceA3oLsnddhLiSbylS89P64mYBo9606 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:nDagMsK80W+sVJVLOex2QgFDvhw false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q07960 uniprotkb:Q9UIA9 intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172410|imex:IM-26378-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004299.1|refseq:XP_011518397.1|dip:DIP-6081N|ensembl:ENSG00000175220(gene)|ensembl:ENST00000311956(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696270 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2A-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:ceA3oLsnddhLiSbylS89P64mYBo9606 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:nDagMsK80W+sVJVLOex2QgFDvhw false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q9UIA9 uniprotkb:Q9NTM9 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 intact:EBI-714918|uniprotkb:Q5TCZ8|uniprotkb:Q9Y321|ensembl:ENSP00000359507 psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:cutc_human(display_long)|uniprotkb:CUTC(gene name)|psi-mi:CUTC(display_short)|uniprotkb:CGI-32(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172443|imex:IM-26378-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 ensembl:ENSG00000119929(gene)|ensembl:ENST00000370476(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006825"(copper ion transport)|go:"GO:0051262"(protein tetramerization)|go:"GO:0055070"(copper ion homeostasis)|interpro:IPR005627(CutC)|interpro:IPR023648|interpro:IPR036822|mint:Q9NTM9|refseq:NP_057044.2|reactome:R-HSA-936837|rcsb pdb:3IWP - - - figure legend:2A-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rogid:MkxQTQ5IGq+/IZzPy3wSurdtB6w9606 rigid:2aGWiJMofw3u4Gqx3u/DmYbWusk false - his tag:n-n|zz tag:n-n|tag:n-n - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P43490 uniprotkb:Q9UIA9 intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172458|imex:IM-26378-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2A-3|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:pcOguf4C/9NKD9eoUzoaRlQ/czI false zz tag:n-n|tag:n-n|his tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P08397 uniprotkb:Q9UIA9 intact:EBI-9090148|uniprotkb:G3V1P4|uniprotkb:G5EA58|uniprotkb:A8K2L0|uniprotkb:Q16012|uniprotkb:P08396|ensembl:ENSP00000498786 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:hem3_human(display_long)|uniprotkb:Hydroxymethylbilane synthase(gene name synonym)|uniprotkb:PBGD(gene name synonym)|uniprotkb:Pre-uroporphyrinogen synthase(gene name synonym)|uniprotkb:UPS(gene name synonym)|uniprotkb:HMBS(gene name)|psi-mi:HMBS(display_short) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172469|imex:IM-26378-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000181.2|refseq:NP_001019553.1|refseq:NP_001245137.1|refseq:NP_001245138.1|refseq:XP_005271588.1|refseq:XP_005271589.1|refseq:XP_016873118.1|ensembl:ENSG00000256269(gene)|go:"GO:0004418"(hydroxymethylbilane synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0018160"(peptidyl-pyrromethane cofactor linkage)|interpro:IPR000860(Tetrapyrrole biosynthesis, hydroxymethylbilane synthase)|interpro:IPR022417|interpro:IPR022418|interpro:IPR022419|interpro:IPR036803|rcsb pdb:3ECR|ensembl:ENST00000652429(transcript)|rcsb pdb:5M6R|rcsb pdb:5M7F|rcsb pdb:7AAJ|rcsb pdb:7AAK|rcsb pdb:7CCX|rcsb pdb:7CCY|rcsb pdb:7CCZ|rcsb pdb:7CD0|reactome:R-HSA-189451|rcsb pdb:3EQ1 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2A-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:aTjyl498kJtf2NyY0oQFyz00ogc9606 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:yjKETSJX1W2cxYhHdmDRFoId7jY false zz tag:n-n|tag:n-n|his tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O60502 uniprotkb:Q9UIA9 intact:EBI-715814|uniprotkb:O75166|uniprotkb:Q86WV0|uniprotkb:Q8IV98|uniprotkb:Q9BVA5|uniprotkb:Q9HAR0|uniprotkb:B7WPB9|uniprotkb:D3DR79|uniprotkb:E9PGF9|ensembl:ENSP00000354850 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:oga_human(display_long)|uniprotkb:OGA(gene name)|psi-mi:OGA(display_short)|uniprotkb:Beta-N-acetylglucosaminidase(gene name synonym)|uniprotkb:Beta-N-acetylhexosaminidase(gene name synonym)|uniprotkb:Beta-hexosaminidase(gene name synonym)|uniprotkb:HEXC(gene name synonym)|uniprotkb:KIAA0679(gene name synonym)|uniprotkb:MEA5(gene name synonym)|uniprotkb:MGEA5(gene name synonym)|uniprotkb:Meningioma-expressed antigen 5(gene name synonym)|uniprotkb:N-acetyl-beta-D-glucosaminidase(gene name synonym)|uniprotkb:N-acetyl-beta-glucosaminidase(gene name synonym)|uniprotkb:Nuclear cytoplasmic O-GlcNAcase and acetyltransferase(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172480|imex:IM-26378-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135906.1|refseq:NP_036347.1|ensembl:ENSG00000198408(gene)|ensembl:ENST00000361464(transcript)|go:"GO:0004415"(hyalurononglucosaminidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006044"(N-acetylglucosamine metabolic process)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016231"(beta-N-acetylglucosaminidase activity)|go:"GO:0102166"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity")|go:"GO:0102167"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity")|go:"GO:0102571"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity")|interpro:IPR011496(Hyaluronidase eukaryotic/prokaryotic)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:2YDQ|rcsb pdb:5M7R|rcsb pdb:5M7S|rcsb pdb:5M7T|rcsb pdb:5M7U|rcsb pdb:5TKE|rcsb pdb:5UHK|rcsb pdb:5UHL|rcsb pdb:5UHO|rcsb pdb:5UHP|rcsb pdb:5UN8|rcsb pdb:5UN9|rcsb pdb:5VVO|rcsb pdb:5VVT|rcsb pdb:5VVU|rcsb pdb:5VVV|rcsb pdb:5VVX|rcsb pdb:6HKI|rcsb pdb:6PM9|go:"GO:0005634"(nucleus) refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2A-5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:KEvP6+2BWwsxrs8hsIjQhKAQGVo9606 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:y16gYQjz18Ip/uFfgEfCphdyo/E false zz tag:n-n|tag:n-n|his tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q9BY41 uniprotkb:Q9UIA9 intact:EBI-6598095|uniprotkb:A6ND12|uniprotkb:A6ND61|ensembl:ENSP00000362674|uniprotkb:A6NET3|uniprotkb:A8MQ62|uniprotkb:B4DKN0|uniprotkb:B4DV22|uniprotkb:Q86VC8|uniprotkb:Q9NP76|uniprotkb:Q9NYH4|uniprotkb:A6NJR3 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:hdac8_human(display_long)|uniprotkb:HDAC8(gene name)|psi-mi:HDAC8(display_short)|uniprotkb:HDACL1(gene name synonym)|uniprotkb:CDA07(orf name) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172490|imex:IM-26378-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147099(gene)|ensembl:ENST00000373573(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR037138|mint:Q9BY41|rcsb pdb:1T64|rcsb pdb:1T67|rcsb pdb:1T69|rcsb pdb:1VKG|rcsb pdb:1W22|rcsb pdb:2V5W|rcsb pdb:2V5X|rcsb pdb:3EW8|rcsb pdb:3EWF|rcsb pdb:3EZP|rcsb pdb:3EZT|rcsb pdb:3F06|rcsb pdb:3F07|rcsb pdb:3F0R|rcsb pdb:3MZ3|rcsb pdb:3MZ4|rcsb pdb:3MZ6|rcsb pdb:3MZ7|rcsb pdb:3RQD|rcsb pdb:3SFF|interpro:IPR023801|rcsb pdb:3SFH|rcsb pdb:4QA0|rcsb pdb:4QA1|rcsb pdb:4QA2|rcsb pdb:4QA3|rcsb pdb:4QA4|rcsb pdb:4QA5|rcsb pdb:4QA6|rcsb pdb:4QA7|rcsb pdb:4RN0|rcsb pdb:4RN1|rcsb pdb:4RN2|rcsb pdb:5BWZ|rcsb pdb:5D1B|rcsb pdb:5D1C|rcsb pdb:5D1D|rcsb pdb:5DC5|rcsb pdb:5DC6|rcsb pdb:5DC7|rcsb pdb:5DC8|rcsb pdb:5FCW|rcsb pdb:5THS|rcsb pdb:5THT|rcsb pdb:5THU|rcsb pdb:5THV|rcsb pdb:5VI6|rcsb pdb:6HSK|rcsb pdb:6ODA|rcsb pdb:6ODB|rcsb pdb:6ODC|rcsb pdb:7JVU|rcsb pdb:7JVV|rcsb pdb:7JVW|reactome:R-HSA-2122947|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|refseq:NP_001159890.1|refseq:NP_001159891.1|refseq:NP_060956.1|refseq:NP_001159894.1|refseq:NP_001159920.1|refseq:NP_001159892.1 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2A-6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:ox+oBoLdr03D6tPUroV2PpavrhE9606 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:3xfpJ8emtp2pBtJVzBomp9FLCg4 false zz tag:n-n|tag:n-n|his tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O14929 uniprotkb:Q9UIA9 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172500|imex:IM-26378-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2A-7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:k8pilGHoAmeHdX4YkSCPOHNL738 false zz tag:n-n|tag:n-n|his tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q53HV7 uniprotkb:Q9UIA9 intact:EBI-749970|uniprotkb:O95862|uniprotkb:Q8NB71|uniprotkb:Q9BWC8|uniprotkb:A8K2K9|uniprotkb:Q0D2M0|ensembl:ENSP00000338606|ensembl:ENSP00000424191|ensembl:ENSP00000507590|ensembl:ENSP00000384828|intact:EBI-16429121 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:smug1_human(display_long)|uniprotkb:SMUG1(gene name)|psi-mi:SMUG1(display_short) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172510|imex:IM-26378-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055126.1|refseq:XP_011536411.1|refseq:XP_011536412.1|refseq:XP_011536413.1|refseq:XP_011536414.1|refseq:XP_011536415.1|refseq:XP_011536416.1|refseq:XP_011536417.1|refseq:XP_011536418.1|refseq:XP_011536419.1|refseq:XP_011536420.1|refseq:XP_011536421.1|refseq:XP_011536422.1|refseq:XP_011536423.1|refseq:NP_001230716.1|refseq:NP_001230717.1|refseq:NP_001230718.1|refseq:NP_001230719.1|refseq:NP_001230720.1|refseq:XP_006719382.1|refseq:XP_006719383.1|refseq:XP_006719384.1|refseq:XP_016874602.1|refseq:XP_016874603.1|refseq:XP_016874604.1|refseq:XP_016874605.1|refseq:XP_016874608.1|ensembl:ENSG00000123415(gene)|ensembl:ENST00000337581(transcript)|ensembl:ENST00000401977(transcript)|ensembl:ENST00000508394(transcript)|ensembl:ENST00000682136(transcript)|go:"GO:0000703"(oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0017065"(single-strand selective uracil DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045008"(depyrimidination)|interpro:IPR036895|interpro:IPR039134|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|refseq:XP_006719385.1|refseq:XP_011536424.1|refseq:XP_016874606.1|refseq:XP_016874607.1|refseq:XP_016874609.1 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2A-8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:spkw9KcBN2lpT8wBFBWzIdlhgtg9606 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:nAwq/PPGFrk6KVHuT1ZhKEt8rrg false zz tag:n-n|tag:n-n|his tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q9D3W4 uniprotkb:P62826 intact:EBI-17170265|ensembl:ENSMUSP00000031420|uniprotkb:Q8BU32 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:gpn3_mouse(display_long)|uniprotkb:Gpn3(gene name)|psi-mi:Gpn3(display_short)|uniprotkb:Atpbd1c(gene name synonym)|uniprotkb:D5Ertd708e(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172527|imex:IM-26378-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029464(gene)|ensembl:ENSMUST00000031420(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|refseq:NP_077178.1 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:gMSlGVRYGHvsJ1/3q7+GfzO1qSA10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:fJeqlkCTJwmZJFQZAP9MWo62Ycg false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9D3W4 uniprotkb:Q9UIA9 intact:EBI-17170265|ensembl:ENSMUSP00000031420|uniprotkb:Q8BU32 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:gpn3_mouse(display_long)|uniprotkb:Gpn3(gene name)|psi-mi:Gpn3(display_short)|uniprotkb:Atpbd1c(gene name synonym)|uniprotkb:D5Ertd708e(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172527|imex:IM-26378-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029464(gene)|ensembl:ENSMUST00000031420(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|refseq:NP_077178.1 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:gMSlGVRYGHvsJ1/3q7+GfzO1qSA10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:fJeqlkCTJwmZJFQZAP9MWo62Ycg false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9CWR2 uniprotkb:P62826 intact:EBI-17170344|ensembl:ENSMUSP00000117410|uniprotkb:Q6P7V6|uniprotkb:Q8BG90 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:smyd3_mouse(display_long)|uniprotkb:Smyd3(gene name)|psi-mi:Smyd3(display_short)|uniprotkb:Zmynd1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172552|imex:IM-26378-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000055067(gene)|ensembl:ENSMUST00000128302(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|reactome:R-MMU-3214841|refseq:NP_081464.1|refseq:XP_006497045.1|refseq:XP_017167700.1|refseq:XP_017167702.1 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:QTEnl1tnx0UmirLb4sS+2D/Vm0Q10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:NUhdNNOAfDkn9qUKnmwKByFD9KA false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9CWR2 uniprotkb:Q9UIA9 intact:EBI-17170344|ensembl:ENSMUSP00000117410|uniprotkb:Q6P7V6|uniprotkb:Q8BG90 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:smyd3_mouse(display_long)|uniprotkb:Smyd3(gene name)|psi-mi:Smyd3(display_short)|uniprotkb:Zmynd1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172552|imex:IM-26378-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000055067(gene)|ensembl:ENSMUST00000128302(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|reactome:R-MMU-3214841|refseq:NP_081464.1|refseq:XP_006497045.1|refseq:XP_017167700.1|refseq:XP_017167702.1 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:QTEnl1tnx0UmirLb4sS+2D/Vm0Q10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:NUhdNNOAfDkn9qUKnmwKByFD9KA false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O35381 uniprotkb:P62826 intact:EBI-643140|uniprotkb:P97437|ensembl:ENSMUSP00000082652 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:an32a_mouse(display_long)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Anp32a(gene name)|psi-mi:Anp32a(display_short)|uniprotkb:Anp32(gene name synonym)|uniprotkb:Lanp(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172576|imex:IM-26378-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033802.2|ensembl:ENSMUSG00000032249(gene)|ensembl:ENSMUST00000085519(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:O35381|rcsb pdb:2JQD|reactome:R-MMU-450520 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:flk6xO1N5PloQyQ9bOBHDzr3Hr010090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:AM3H/+nRij/ZXPXoxYkl+2UOKYA false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O35381 uniprotkb:Q9UIA9 intact:EBI-643140|uniprotkb:P97437|ensembl:ENSMUSP00000082652 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:an32a_mouse(display_long)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Anp32a(gene name)|psi-mi:Anp32a(display_short)|uniprotkb:Anp32(gene name synonym)|uniprotkb:Lanp(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172576|imex:IM-26378-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033802.2|ensembl:ENSMUSG00000032249(gene)|ensembl:ENSMUST00000085519(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:O35381|rcsb pdb:2JQD|reactome:R-MMU-450520 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:flk6xO1N5PloQyQ9bOBHDzr3Hr010090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:AM3H/+nRij/ZXPXoxYkl+2UOKYA false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q61074 uniprotkb:P62826 intact:EBI-642919|ensembl:ENSMUSP00000031032 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:ppm1g_mouse(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:Fibroblast growth factor-inducible protein 13(gene name synonym)|uniprotkb:Ppm1g(gene name)|psi-mi:Ppm1g(display_short)|uniprotkb:Fin13(gene name synonym)|uniprotkb:Ppm1c(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172591|imex:IM-26378-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032040.1|ensembl:ENSMUSG00000029147(gene)|ensembl:ENSMUST00000031032(transcript)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q61074 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:OazpV/JqeZD+TpovURxYWY9t6VI10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:LbP0HsUFbEjBpdo1rGYR6O60MOs false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q61074 uniprotkb:Q9UIA9 intact:EBI-642919|ensembl:ENSMUSP00000031032 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:ppm1g_mouse(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:Fibroblast growth factor-inducible protein 13(gene name synonym)|uniprotkb:Ppm1g(gene name)|psi-mi:Ppm1g(display_short)|uniprotkb:Fin13(gene name synonym)|uniprotkb:Ppm1c(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172591|imex:IM-26378-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032040.1|ensembl:ENSMUSG00000029147(gene)|ensembl:ENSMUST00000031032(transcript)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q61074 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:OazpV/JqeZD+TpovURxYWY9t6VI10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:LbP0HsUFbEjBpdo1rGYR6O60MOs false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9EQU5 uniprotkb:P62826 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172606|imex:IM-26378-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:gTm30S3LS49LlTGOO5gr/0lYavY false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9EQU5 uniprotkb:Q9UIA9 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172606|imex:IM-26378-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:gTm30S3LS49LlTGOO5gr/0lYavY false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O09012 uniprotkb:P62826 intact:EBI-646301|uniprotkb:Q3UM58|uniprotkb:Q8K2V5|uniprotkb:Q91YC7|ensembl:ENSMUSP00000049132|ensembl:ENSMUSP00000108151 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:pex5_mouse(display_long)|uniprotkb:Peroxisome receptor 1(gene name synonym)|uniprotkb:Peroxisomal C-terminal targeting signal import receptor(gene name synonym)|uniprotkb:PTS1-BP(gene name synonym)|uniprotkb:Peroxin-5(gene name synonym)|uniprotkb:PXR1P(gene name synonym)|uniprotkb:Pex5(gene name)|psi-mi:Pex5(display_short)|uniprotkb:Pxr1(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172621|imex:IM-26378-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033021.2|refseq:NP_787947.1|refseq:NP_001264734.1|refseq:XP_006505821.1|refseq:XP_006505822.1|refseq:NP_001264259.1|refseq:XP_017176951.1|ensembl:ENSMUSG00000005069(gene)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|ensembl:ENSMUST00000035861(transcript)|ensembl:ENSMUST00000112532(transcript)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051262"(protein tetramerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|interpro:IPR024113|reactome:R-MMU-8866654|go:"GO:0000038"(very long-chain fatty acid metabolic process)|reactome:R-MMU-9033241|reactome:R-MMU-9664873|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0001764"(neuron migration)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion) refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:GqfIILxRcIiR64Sc7t0ElWui3dw10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:GrbF5d5NU38F22JYlbZKzwPLK/k false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O09012 uniprotkb:Q9UIA9 intact:EBI-646301|uniprotkb:Q3UM58|uniprotkb:Q8K2V5|uniprotkb:Q91YC7|ensembl:ENSMUSP00000049132|ensembl:ENSMUSP00000108151 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:pex5_mouse(display_long)|uniprotkb:Peroxisome receptor 1(gene name synonym)|uniprotkb:Peroxisomal C-terminal targeting signal import receptor(gene name synonym)|uniprotkb:PTS1-BP(gene name synonym)|uniprotkb:Peroxin-5(gene name synonym)|uniprotkb:PXR1P(gene name synonym)|uniprotkb:Pex5(gene name)|psi-mi:Pex5(display_short)|uniprotkb:Pxr1(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172621|imex:IM-26378-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033021.2|refseq:NP_787947.1|refseq:NP_001264734.1|refseq:XP_006505821.1|refseq:XP_006505822.1|refseq:NP_001264259.1|refseq:XP_017176951.1|ensembl:ENSMUSG00000005069(gene)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|ensembl:ENSMUST00000035861(transcript)|ensembl:ENSMUST00000112532(transcript)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051262"(protein tetramerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|interpro:IPR024113|reactome:R-MMU-8866654|go:"GO:0000038"(very long-chain fatty acid metabolic process)|reactome:R-MMU-9033241|reactome:R-MMU-9664873|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0001764"(neuron migration)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion) refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:GqfIILxRcIiR64Sc7t0ElWui3dw10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:GrbF5d5NU38F22JYlbZKzwPLK/k false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8VE09 uniprotkb:P62826 intact:EBI-8365622|intact:MINT-4390945|uniprotkb:Q9CYV6 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:tt39c_mouse(display_long)|uniprotkb:Ttc39c(gene name)|psi-mi:Ttc39c(display_short) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172636|imex:IM-26378-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_082617.2|interpro:IPR019412|mint:Q8VE09|go:"GO:0032474"(otolith morphogenesis)|go:"GO:0060271"(cilium assembly) refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - comment:mint - figure legend:2B-7|comment:"The authors have stated that binding in (Figure 2b) (-RanGTP) is negligible and the interaction between Ttc39c and Xpo7 is RanGTP dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:PkuhPjB0mc5z/Sl+y98wdJhSi1s10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:mGR5gibYH94uu+4y5XYZDvWppQk false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8VE09 uniprotkb:Q9UIA9 intact:EBI-8365622|intact:MINT-4390945|uniprotkb:Q9CYV6 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:tt39c_mouse(display_long)|uniprotkb:Ttc39c(gene name)|psi-mi:Ttc39c(display_short) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172636|imex:IM-26378-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_082617.2|interpro:IPR019412|mint:Q8VE09|go:"GO:0032474"(otolith morphogenesis)|go:"GO:0060271"(cilium assembly) refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - comment:mint - figure legend:2B-7|comment:"The authors have stated that binding in (Figure 2b) (-RanGTP) is negligible and the interaction between Ttc39c and Xpo7 is RanGTP dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:PkuhPjB0mc5z/Sl+y98wdJhSi1s10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:mGR5gibYH94uu+4y5XYZDvWppQk false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8VCE2 uniprotkb:P62826 intact:EBI-17170404|ensembl:ENSMUSP00000076217 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:gpn1_mouse(display_long)|uniprotkb:Gpn1(gene name)|psi-mi:Gpn1(display_short)|uniprotkb:Mbdin(gene name synonym)|uniprotkb:Xab1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172666|imex:IM-26378-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000064037(gene)|ensembl:ENSMUST00000076949(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|refseq:NP_598517.1 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:QsNvVutIiDD20I99c65U1XUXy1g10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:O4GW8+18zRkqEAQZ1m1OBLWrn1A false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8VCE2 uniprotkb:Q9UIA9 intact:EBI-17170404|ensembl:ENSMUSP00000076217 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:gpn1_mouse(display_long)|uniprotkb:Gpn1(gene name)|psi-mi:Gpn1(display_short)|uniprotkb:Mbdin(gene name synonym)|uniprotkb:Xab1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172666|imex:IM-26378-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000064037(gene)|ensembl:ENSMUST00000076949(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|refseq:NP_598517.1 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:QsNvVutIiDD20I99c65U1XUXy1g10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:O4GW8+18zRkqEAQZ1m1OBLWrn1A false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Z0P7 uniprotkb:P62826 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172681|imex:IM-26378-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:Nbv/+N4caIJipjHoFphTEl171Dc false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Z0P7 uniprotkb:Q9UIA9 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172681|imex:IM-26378-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:Nbv/+N4caIJipjHoFphTEl171Dc false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P97822 uniprotkb:P62826 intact:EBI-8357774|uniprotkb:Q8BPF8|uniprotkb:Q3TH89|uniprotkb:Q9CZD2|uniprotkb:Q8C7Q8|uniprotkb:Q8C2L4|intact:MINT-4087684|intact:EBI-17172721|uniprotkb:E9Q5H9|uniprotkb:Q3TX26|ensembl:ENSMUSP00000128483 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:an32e_mouse(display_long)|uniprotkb:Anp32e(gene name)|psi-mi:Anp32e(display_short)|uniprotkb:Cpd1(gene name synonym)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:Cerebellar postnatal development protein 1(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172705|imex:IM-26378-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240687.1|refseq:NP_001240686.1|refseq:NP_075699.3|ensembl:ENSMUSG00000015749(gene)|ensembl:ENSMUST00000165307(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043486"(histone exchange)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P97822 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - function:"Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity"|comment:mint - figure legend:2B-10|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/07/05 rogid:KMIegWYJxkmzPWUNdDHwxRm+A1Y10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:YhWadEOtND1FzKAkbwGqu1jmymc false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P97822 uniprotkb:Q9UIA9 intact:EBI-8357774|uniprotkb:Q8BPF8|uniprotkb:Q3TH89|uniprotkb:Q9CZD2|uniprotkb:Q8C7Q8|uniprotkb:Q8C2L4|intact:MINT-4087684|intact:EBI-17172721|uniprotkb:E9Q5H9|uniprotkb:Q3TX26|ensembl:ENSMUSP00000128483 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:an32e_mouse(display_long)|uniprotkb:Anp32e(gene name)|psi-mi:Anp32e(display_short)|uniprotkb:Cpd1(gene name synonym)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:Cerebellar postnatal development protein 1(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172705|imex:IM-26378-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240687.1|refseq:NP_001240686.1|refseq:NP_075699.3|ensembl:ENSMUSG00000015749(gene)|ensembl:ENSMUST00000165307(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043486"(histone exchange)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P97822 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - function:"Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity"|comment:mint - figure legend:2B-10|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/07/05 rogid:KMIegWYJxkmzPWUNdDHwxRm+A1Y10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:YhWadEOtND1FzKAkbwGqu1jmymc false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Z1K5 uniprotkb:P62826 intact:EBI-8312579|ensembl:ENSMUSP00000126531|uniprotkb:Q8CFJ4|uniprotkb:Q6PF92|intact:MINT-4088309|uniprotkb:E9Q1X3 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:ari1_mouse(display_long)|uniprotkb:Arih1(gene name)|psi-mi:Arih1(display_short)|uniprotkb:Ari(gene name synonym)|uniprotkb:Ubch7bp(gene name synonym)|uniprotkb:Uip77(gene name synonym)|uniprotkb:Protein ariadne-1 homolog(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-binding protein 1(gene name synonym)|uniprotkb:UbcH7-binding protein(gene name synonym)|uniprotkb:UbcM4-interacting protein 77(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ARIH1(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172733|imex:IM-26378-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:Q9Z1K5|reactome:R-MMU-1169408|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSMUSG00000025234(gene)|ensembl:ENSMUST00000171975(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097413"(Lewy body)|refseq:NP_064311.2 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - comment:mint|function:Might act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates - figure legend:2B-11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:ZYzYvLjbsUa6q1rOTaHWJatXliI10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:b/HvCEmT/aG6W53N9Uj2JW6ggck false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Z1K5 uniprotkb:Q9UIA9 intact:EBI-8312579|ensembl:ENSMUSP00000126531|uniprotkb:Q8CFJ4|uniprotkb:Q6PF92|intact:MINT-4088309|uniprotkb:E9Q1X3 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:ari1_mouse(display_long)|uniprotkb:Arih1(gene name)|psi-mi:Arih1(display_short)|uniprotkb:Ari(gene name synonym)|uniprotkb:Ubch7bp(gene name synonym)|uniprotkb:Uip77(gene name synonym)|uniprotkb:Protein ariadne-1 homolog(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-binding protein 1(gene name synonym)|uniprotkb:UbcH7-binding protein(gene name synonym)|uniprotkb:UbcM4-interacting protein 77(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ARIH1(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172733|imex:IM-26378-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:Q9Z1K5|reactome:R-MMU-1169408|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSMUSG00000025234(gene)|ensembl:ENSMUST00000171975(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097413"(Lewy body)|refseq:NP_064311.2 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - comment:mint|function:Might act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates - figure legend:2B-11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:ZYzYvLjbsUa6q1rOTaHWJatXliI10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:b/HvCEmT/aG6W53N9Uj2JW6ggck false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P58043 uniprotkb:P62826 intact:EBI-9638431|ensembl:ENSMUSP00000030724 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:sesn2_mouse(display_long)|uniprotkb:Sesn2(gene name)|psi-mi:Sesn2(display_short) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172748|imex:IM-26378-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659156.1|ensembl:ENSMUSG00000028893(gene)|ensembl:ENSMUST00000030724(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009749"(response to glucose)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032542"(sulfiredoxin activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046323"(glucose import)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070728"(leucine binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901031"(regulation of response to reactive oxygen species)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1990253"(cellular response to leucine starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|interpro:IPR006730("PA26 p53-induced protein (sestrin)")|interpro:IPR029032|mint:P58043|reactome:R-MMU-5628897|reactome:R-MMU-9639288 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-12|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:6NEyjqFHWanDDNmCJ0P0y4IC7gM10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:GNABBwnICrmzvV9r/s/TRJbdDUw false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P58043 uniprotkb:Q9UIA9 intact:EBI-9638431|ensembl:ENSMUSP00000030724 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:sesn2_mouse(display_long)|uniprotkb:Sesn2(gene name)|psi-mi:Sesn2(display_short) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172748|imex:IM-26378-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659156.1|ensembl:ENSMUSG00000028893(gene)|ensembl:ENSMUST00000030724(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009749"(response to glucose)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032542"(sulfiredoxin activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046323"(glucose import)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070728"(leucine binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901031"(regulation of response to reactive oxygen species)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1990253"(cellular response to leucine starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|interpro:IPR006730("PA26 p53-induced protein (sestrin)")|interpro:IPR029032|mint:P58043|reactome:R-MMU-5628897|reactome:R-MMU-9639288 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-12|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:6NEyjqFHWanDDNmCJ0P0y4IC7gM10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:GNABBwnICrmzvV9r/s/TRJbdDUw false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8BP48 uniprotkb:P62826 intact:EBI-3870579|ensembl:ENSMUSP00000029804 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:map11_mouse(display_long)|uniprotkb:Metap1(gene name)|psi-mi:Metap1(display_short)|uniprotkb:Peptidase M 1(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172763|imex:IM-26378-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_780433.1|ensembl:ENSMUSG00000005813(gene)|ensembl:ENSMUST00000029804(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|interpro:IPR031615|interpro:IPR036005|mint:Q8BP48|reactome:R-MMU-2514859 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:gfQHRxpM/VdAT4JEKmIWEJ94c6M10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:KzLbSnFVSuBCYkStoySgG76HMeM false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8BP48 uniprotkb:Q9UIA9 intact:EBI-3870579|ensembl:ENSMUSP00000029804 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:map11_mouse(display_long)|uniprotkb:Metap1(gene name)|psi-mi:Metap1(display_short)|uniprotkb:Peptidase M 1(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172763|imex:IM-26378-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_780433.1|ensembl:ENSMUSG00000005813(gene)|ensembl:ENSMUST00000029804(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|interpro:IPR031615|interpro:IPR036005|mint:Q8BP48|reactome:R-MMU-2514859 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:gfQHRxpM/VdAT4JEKmIWEJ94c6M10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:KzLbSnFVSuBCYkStoySgG76HMeM false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P97822 uniprotkb:P62826 intact:EBI-8357774|uniprotkb:Q8BPF8|uniprotkb:Q3TH89|uniprotkb:Q9CZD2|uniprotkb:Q8C7Q8|uniprotkb:Q8C2L4|intact:MINT-4087684|intact:EBI-17172721|uniprotkb:E9Q5H9|uniprotkb:Q3TX26|ensembl:ENSMUSP00000128483 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:an32e_mouse(display_long)|uniprotkb:Anp32e(gene name)|psi-mi:Anp32e(display_short)|uniprotkb:Cpd1(gene name synonym)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:Cerebellar postnatal development protein 1(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172778|imex:IM-26378-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240687.1|refseq:NP_001240686.1|refseq:NP_075699.3|ensembl:ENSMUSG00000015749(gene)|ensembl:ENSMUST00000165307(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043486"(histone exchange)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P97822 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - function:"Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity"|comment:mint - figure legend:2B-14|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:KMIegWYJxkmzPWUNdDHwxRm+A1Y10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:YhWadEOtND1FzKAkbwGqu1jmymc false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P97822 uniprotkb:Q9UIA9 intact:EBI-8357774|uniprotkb:Q8BPF8|uniprotkb:Q3TH89|uniprotkb:Q9CZD2|uniprotkb:Q8C7Q8|uniprotkb:Q8C2L4|intact:MINT-4087684|intact:EBI-17172721|uniprotkb:E9Q5H9|uniprotkb:Q3TX26|ensembl:ENSMUSP00000128483 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:an32e_mouse(display_long)|uniprotkb:Anp32e(gene name)|psi-mi:Anp32e(display_short)|uniprotkb:Cpd1(gene name synonym)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:Cerebellar postnatal development protein 1(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172778|imex:IM-26378-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240687.1|refseq:NP_001240686.1|refseq:NP_075699.3|ensembl:ENSMUSG00000015749(gene)|ensembl:ENSMUST00000165307(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043486"(histone exchange)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P97822 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - function:"Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity"|comment:mint - figure legend:2B-14|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:KMIegWYJxkmzPWUNdDHwxRm+A1Y10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:YhWadEOtND1FzKAkbwGqu1jmymc false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UIA9 uniprotkb:P16381 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 intact:EBI-773139|ensembl:ENSMUSP00000035261 psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:ddx3l_mouse(display_long)|uniprotkb:D1Pas1(gene name)|psi-mi:D1Pas1(display_short)|uniprotkb:Pl10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-17172808|imex:IM-26378-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 refseq:NP_149068.1|ensembl:ENSMUSG00000039224(gene)|ensembl:ENSMUST00000045108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417 - - - figure legend:2B-18|comment:The authors state that they believe that RanGTP does not contribute to Xpo7-Ddx3xl interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/11 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rogid:8oOwLE3GJgEG16k1LZwqP8TmLqU10090 rigid:LjwhcW157DSl/8y95QjuLRHDRcA false - his tag:n-n|zz tag:n-n|tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q60737 uniprotkb:P62826 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172823|imex:IM-26378-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:2B-16|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:Secv6rvTlzIFpxzJboB5cxfqOII false his tag:n-n|zz tag:n-n|tag:n-n mutation:69-69|sufficient binding region:5-180 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q60737 uniprotkb:Q9UIA9 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512 psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aksu et al. (2018) pubmed:29748336|pubmed:unassigned1673|imex:IM-26378 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-17172823|imex:IM-26378-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9 - - - figure legend:2B-16|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/04/10 2018/04/12 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606 rigid:Secv6rvTlzIFpxzJboB5cxfqOII false his tag:n-n|zz tag:n-n|tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)