#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5Y4Y6 uniprotkb:Q5Y4Y6 intact:EBI-20627698|uniprotkb:A2A4X5|ensembl:ENSMUSP00000073022 intact:EBI-20627698|uniprotkb:A2A4X5|ensembl:ENSMUSP00000073022 psi-mi:gsda3_mouse(display_long)|uniprotkb:Gasdermin-3(gene name synonym)|uniprotkb:Gsdma3(gene name)|psi-mi:Gsdma3(display_short)|uniprotkb:Gsdm3(gene name synonym) psi-mi:gsda3_mouse(display_long)|uniprotkb:Gasdermin-3(gene name synonym)|uniprotkb:Gsdma3(gene name)|psi-mi:Gsdma3(display_short)|uniprotkb:Gsdm3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Ruan et al. (2018) pubmed:29695864|imex:IM-26752 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-20627727|wwpdb:6CB8|emdb:EMD-7449|emdb:EMD-7450|emdb:EMD-7451|imex:IM-26752-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007462.1|refseq:XP_006533737.1|ensembl:ENSMUSG00000064224(gene)|ensembl:ENSMUST00000073295(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001942"(hair follicle development)|go:"GO:0001949"(sebaceous gland cell differentiation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012501"(programmed cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022829"(wide pore channel activity)|go:"GO:0030879"(mammary gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036331"(avascular cornea development in camera-type eye)|go:"GO:0042633"(hair cycle)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051886"(negative regulation of timing of anagen)|go:"GO:0070269"(pyroptosis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901612"(cardiolipin binding)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR007677(DFNA5 protein)|interpro:IPR040460|interpro:IPR041263|rcsb pdb:5B5R|rcsb pdb:6CB8 refseq:NP_001007462.1|refseq:XP_006533737.1|ensembl:ENSMUSG00000064224(gene)|ensembl:ENSMUST00000073295(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001942"(hair follicle development)|go:"GO:0001949"(sebaceous gland cell differentiation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012501"(programmed cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022829"(wide pore channel activity)|go:"GO:0030879"(mammary gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036331"(avascular cornea development in camera-type eye)|go:"GO:0042633"(hair cycle)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051886"(negative regulation of timing of anagen)|go:"GO:0070269"(pyroptosis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901612"(cardiolipin binding)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR007677(DFNA5 protein)|interpro:IPR040460|interpro:IPR041263|rcsb pdb:5B5R|rcsb pdb:6CB8 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2018/07/18 2018/07/23 rogid:h2V3iwMONv0gPZZy5BUVAOEVq4o10090 rogid:h2V3iwMONv0gPZZy5BUVAOEVq4o10090 rigid:1Moi8JC021qLoTkYoKjePLlHM6k false binding-associated region:1-262 binding-associated region:1-262 26 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:2287"(identification by structure determination)