#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P28737 uniprotkb:Q12421 intact:EBI-11435|ensemblfungi:YGR028W|uniprotkb:D6VUG3 intact:EBI-34768|uniprotkb:Q03939|uniprotkb:D6VS08|ensemblfungi:YDR022C psi-mi:msp1_yeast(display_long)|uniprotkb:MSP1(gene name)|psi-mi:MSP1(display_short)|uniprotkb:YTA4(gene name synonym)|uniprotkb:Tat-binding homolog 4(gene name synonym)|uniprotkb:YGR028W(locus name)|uniprotkb:Mitochondrial sorting of proteins(gene name synonym) psi-mi:atg31_yeast(display_long)|uniprotkb:ATG31(gene name)|psi-mi:ATG31(display_short)|uniprotkb:CIK1 suppressor protein 1(gene name synonym)|uniprotkb:CIS1(gene name synonym)|uniprotkb:Protein CIS1(gene name synonym)|uniprotkb:PZD196(orf name)|uniprotkb:YD9335.08c(orf name)|uniprotkb:YDR022C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Weidberg et al. (2018) pubmed:29650645|imex:IM-26772 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20620276|imex:IM-26772-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR028W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|ensemblfungi:YGR028W(gene)|go:"GO:0034214"(protein hexamerization)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:5W0T|reactome:R-SCE-9603798|refseq:NP_011542.3|sgd:S000003260|mint:P28737|dip:DIP-8029N refseq:NP_010305.1|sgd:S000002429|mint:Q12421|dip:DIP-2667N|ensemblfungi:YDR022C(gene)|ensemblfungi:YDR022C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000741"(karyogamy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018621 - - crc64:CC2396854F29D250 figure legend:Fig 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/09 2018/07/09 rogid:UFZA88NVrknmWX1JBM1aeE0xUt8559292 rogid:qwAx0SPS9A+ufGaQrt+hF2/tggg559292 rigid:WG7zxXMYtzQD/Y53GNK5RdEGWPk false mutation:193-193|flag tag:c-c v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P28737 uniprotkb:Q12421 intact:EBI-11435|ensemblfungi:YGR028W|uniprotkb:D6VUG3 intact:EBI-34768|uniprotkb:Q03939|uniprotkb:D6VS08|ensemblfungi:YDR022C psi-mi:msp1_yeast(display_long)|uniprotkb:MSP1(gene name)|psi-mi:MSP1(display_short)|uniprotkb:YTA4(gene name synonym)|uniprotkb:Tat-binding homolog 4(gene name synonym)|uniprotkb:YGR028W(locus name)|uniprotkb:Mitochondrial sorting of proteins(gene name synonym) psi-mi:atg31_yeast(display_long)|uniprotkb:ATG31(gene name)|psi-mi:ATG31(display_short)|uniprotkb:CIK1 suppressor protein 1(gene name synonym)|uniprotkb:CIS1(gene name synonym)|uniprotkb:Protein CIS1(gene name synonym)|uniprotkb:PZD196(orf name)|uniprotkb:YD9335.08c(orf name)|uniprotkb:YDR022C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Weidberg et al. (2018) pubmed:29650645|imex:IM-26772 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20620282|imex:IM-26772-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR028W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|ensemblfungi:YGR028W(gene)|go:"GO:0034214"(protein hexamerization)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:5W0T|reactome:R-SCE-9603798|refseq:NP_011542.3|sgd:S000003260|mint:P28737|dip:DIP-8029N refseq:NP_010305.1|sgd:S000002429|mint:Q12421|dip:DIP-2667N|ensemblfungi:YDR022C(gene)|ensemblfungi:YDR022C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000741"(karyogamy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018621 - - crc64:CC2396854F29D250 figure legend:Fig S6-A & Fig S6-B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/09 2018/07/10 rogid:UFZA88NVrknmWX1JBM1aeE0xUt8559292 rogid:qwAx0SPS9A+ufGaQrt+hF2/tggg559292 rigid:WG7zxXMYtzQD/Y53GNK5RdEGWPk false flag tag:c-c|mutation:193-193 v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12421 uniprotkb:P07213 intact:EBI-34768|uniprotkb:Q03939|uniprotkb:D6VS08|ensemblfungi:YDR022C intact:EBI-12551|uniprotkb:D6W162|ensemblfungi:YNL121C|uniprotkb:B0KZR5|uniprotkb:B0KZS4|uniprotkb:B0KZU2|uniprotkb:B0KZY7|uniprotkb:B0KZZ6|uniprotkb:B0L005|uniprotkb:B0L023 psi-mi:atg31_yeast(display_long)|uniprotkb:ATG31(gene name)|psi-mi:ATG31(display_short)|uniprotkb:CIK1 suppressor protein 1(gene name synonym)|uniprotkb:CIS1(gene name synonym)|uniprotkb:Protein CIS1(gene name synonym)|uniprotkb:PZD196(orf name)|uniprotkb:YD9335.08c(orf name)|uniprotkb:YDR022C(locus name) psi-mi:tom70_yeast(display_long)|uniprotkb:TOM70(gene name)|psi-mi:TOM70(display_short)|uniprotkb:MAS70(gene name synonym)|uniprotkb:YNL121C(locus name)|uniprotkb:N1905(orf name)|uniprotkb:OMP1(gene name synonym)|uniprotkb:70 kDa mitochondrial outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Weidberg et al. (2018) pubmed:29650645|imex:IM-26772 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20620286|imex:IM-26772-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010305.1|sgd:S000002429|mint:Q12421|dip:DIP-2667N|ensemblfungi:YDR022C(gene)|ensemblfungi:YDR022C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000741"(karyogamy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018621 go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR005687(Mitochondrial import translocase, subunit Tom70)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2GW1|ensemblfungi:YNL121C(gene)|ensemblfungi:YNL121C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_014278.3|sgd:S000005065|dip:DIP-2301N|mint:P07213 - crc64:CC2396854F29D250 crc64:664B8FC32CCE39A2 figure legend:Fig 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/09 2018/07/10 rogid:qwAx0SPS9A+ufGaQrt+hF2/tggg559292 rogid:0AbL99N4pd8IencG4+mcRH/QKOU559292 rigid:6rns6Lk5rCljeV4//hq0NNcqmPw false v5 tag:c-c green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12421 uniprotkb:P28737 intact:EBI-34768|uniprotkb:Q03939|uniprotkb:D6VS08|ensemblfungi:YDR022C intact:EBI-11435|ensemblfungi:YGR028W|uniprotkb:D6VUG3 psi-mi:atg31_yeast(display_long)|uniprotkb:ATG31(gene name)|psi-mi:ATG31(display_short)|uniprotkb:CIK1 suppressor protein 1(gene name synonym)|uniprotkb:CIS1(gene name synonym)|uniprotkb:Protein CIS1(gene name synonym)|uniprotkb:PZD196(orf name)|uniprotkb:YD9335.08c(orf name)|uniprotkb:YDR022C(locus name) psi-mi:msp1_yeast(display_long)|uniprotkb:MSP1(gene name)|psi-mi:MSP1(display_short)|uniprotkb:YTA4(gene name synonym)|uniprotkb:Tat-binding homolog 4(gene name synonym)|uniprotkb:YGR028W(locus name)|uniprotkb:Mitochondrial sorting of proteins(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Weidberg et al. (2018) pubmed:29650645|imex:IM-26772 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20620286|imex:IM-26772-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010305.1|sgd:S000002429|mint:Q12421|dip:DIP-2667N|ensemblfungi:YDR022C(gene)|ensemblfungi:YDR022C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000741"(karyogamy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018621 ensemblfungi:YGR028W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|ensemblfungi:YGR028W(gene)|go:"GO:0034214"(protein hexamerization)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:5W0T|reactome:R-SCE-9603798|refseq:NP_011542.3|sgd:S000003260|mint:P28737|dip:DIP-8029N - crc64:CC2396854F29D250 - figure legend:Fig 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/09 2018/07/10 rogid:qwAx0SPS9A+ufGaQrt+hF2/tggg559292 rogid:UFZA88NVrknmWX1JBM1aeE0xUt8559292 rigid:6rns6Lk5rCljeV4//hq0NNcqmPw false v5 tag:c-c mutation:193-193|flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P07213 uniprotkb:P28737 intact:EBI-12551|uniprotkb:D6W162|ensemblfungi:YNL121C|uniprotkb:B0KZR5|uniprotkb:B0KZS4|uniprotkb:B0KZU2|uniprotkb:B0KZY7|uniprotkb:B0KZZ6|uniprotkb:B0L005|uniprotkb:B0L023 intact:EBI-11435|ensemblfungi:YGR028W|uniprotkb:D6VUG3 psi-mi:tom70_yeast(display_long)|uniprotkb:TOM70(gene name)|psi-mi:TOM70(display_short)|uniprotkb:MAS70(gene name synonym)|uniprotkb:YNL121C(locus name)|uniprotkb:N1905(orf name)|uniprotkb:OMP1(gene name synonym)|uniprotkb:70 kDa mitochondrial outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym) psi-mi:msp1_yeast(display_long)|uniprotkb:MSP1(gene name)|psi-mi:MSP1(display_short)|uniprotkb:YTA4(gene name synonym)|uniprotkb:Tat-binding homolog 4(gene name synonym)|uniprotkb:YGR028W(locus name)|uniprotkb:Mitochondrial sorting of proteins(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Weidberg et al. (2018) pubmed:29650645|imex:IM-26772 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20620291|imex:IM-26772-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR005687(Mitochondrial import translocase, subunit Tom70)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2GW1|ensemblfungi:YNL121C(gene)|ensemblfungi:YNL121C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_014278.3|sgd:S000005065|dip:DIP-2301N|mint:P07213 ensemblfungi:YGR028W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|ensemblfungi:YGR028W(gene)|go:"GO:0034214"(protein hexamerization)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:5W0T|reactome:R-SCE-9603798|refseq:NP_011542.3|sgd:S000003260|mint:P28737|dip:DIP-8029N - crc64:664B8FC32CCE39A2 - figure legend:Fig 7D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/09 2018/08/21 rogid:0AbL99N4pd8IencG4+mcRH/QKOU559292 rogid:UFZA88NVrknmWX1JBM1aeE0xUt8559292 rigid:WeN4BVcq4TrratfqnHk8L4Cyb98 false green fluorescent protein tag:c-c mutation:193-193|flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)