#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q1XA76	uniprotkb:Q1XA76	intact:EBI-15659618|ensembl:ENSGALP00000057289	intact:EBI-15659618|ensembl:ENSGALP00000057289	psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym)	psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Yoder et al. (2018)	pubmed:29513651|imex:IM-26873	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21003240|imex:IM-26873-1|wwpdb:5WKU|wwpdb:5WKV	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N	ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N	-	-	-	figure legend:Fig 1, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/12/05	2018/12/12	rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031	rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031	rigid:EfvUqVuFP+M1HaBwoRP7WURMwwI	false	binding-associated region:25-463	binding-associated region:25-463	3	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q1XA76	uniprotkb:Q1XA76	intact:EBI-15659618|ensembl:ENSGALP00000057289	intact:EBI-15659618|ensembl:ENSGALP00000057289	psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym)	psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Yoder et al. (2018)	pubmed:29513651|imex:IM-26873	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21003254|imex:IM-26873-3|wwpdb:6AVE|emdb:EMD-7009	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N	ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N	-	-	-	figure legend:Fig 1, Extended Data Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/12/05	2018/12/12	rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031	rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031	rigid:EfvUqVuFP+M1HaBwoRP7WURMwwI	false	-	-	3	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)