#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q86U44 uniprotkb:Q7Z6Z7 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q8N726 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-625922|uniprotkb:Q13195|uniprotkb:Q13399|uniprotkb:Q16360|uniprotkb:Q7KZR9|ensembl:ENSP00000432664|ensembl:ENSP00000462950|uniprotkb:D3DRK2 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:arf_human(display_long)|uniprotkb:p14ARF(gene name synonym)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:MLM(gene name synonym)|uniprotkb:Alternative reading frame(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000147889(gene)|ensembl:ENST00000530628(transcript)|ensembl:ENST00000579755(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0050821"(protein stabilization)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090398"(cellular senescence)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)|mint:Q8N726|reactome:R-HSA-111471|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-6804757|reactome:R-HSA-69541|reactome:R-HSA-8941858|reactome:R-HSA-9645722|reactome:R-HSA-9646303|reactome:R-HSA-9646304|refseq:NP_478102.2|dip:DIP-24171N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:zdbvJmkrI/zJFL+Enq5jTM1Csdw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9BVQ7 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-7950854|uniprotkb:Q9HA41|intact:MINT-4718214|uniprotkb:Q9H8W7|uniprotkb:C9JHR5|ensembl:ENSP00000305494 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:spa5l_human(display_long)|uniprotkb:SPATA5L1(gene name)|psi-mi:SPATA5L1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_076968.2|refseq:NP_001310569.1|ensembl:ENSG00000171763(gene)|ensembl:ENST00000305560(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|mint:Q9BVQ7 - - comment:mint|comment:homomint figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:8FTQdkGYS4xx3pmJDk9xNtPy3Ao9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q68DL7 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-11323181|uniprotkb:A6NME8|ensembl:ENSP00000464330 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:cr063_human(display_long)|uniprotkb:C18orf63(gene name)|psi-mi:C18orf63(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001167594.1|ensembl:ENSG00000206043(gene)|ensembl:ENST00000579455(transcript)|interpro:IPR031643 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:PJOEDQ5xaJ+48HJclZUnMLlpabA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01597 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-20595286|uniprotkb:A0A0B4J1Z7|uniprotkb:A0A0C4DH57|uniprotkb:A0A0U1RVJ5|uniprotkb:P01600|uniprotkb:P01606|uniprotkb:P01612|uniprotkb:P04431|ensembl:ENSP00000419058|ensembl:ENSP00000488680 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kv139_human(display_long)|uniprotkb:Ig kappa chain V-I region DEE(gene name synonym)|uniprotkb:Ig kappa chain V-I region Hau(gene name synonym)|uniprotkb:Ig kappa chain V-I region Mev(gene name synonym)|uniprotkb:Ig kappa chain V-I region OU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Walker(gene name synonym)|uniprotkb:IGKV1-39(gene name)|psi-mi:IGKV1-39(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000282120(gene)|ensembl:ENSG00000242371(gene)|ensembl:ENST00000498574(transcript)|ensembl:ENST00000631411(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1DGX|rcsb pdb:1F6L|rcsb pdb:3UPA|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:CuWhPlNprI6ZmYzfxYPQZAto6vk9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01602 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2371313|uniprotkb:A0A075B6S8|intact:EBI-4286966|uniprotkb:P01596|uniprotkb:P01598|uniprotkb:P01604|ensembl:ENSP00000420436|ensembl:ENSP00000488639 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kv105_human(display_long)|uniprotkb:IGKV1-5(gene name)|psi-mi:IGKV1-5(display_short)|uniprotkb:Ig kappa chain V-I region HK102(gene name synonym)|uniprotkb:Ig kappa chain V-I region CAR(gene name synonym)|uniprotkb:Ig kappa chain V-I region EU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Kue(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000243466(gene)|ensembl:ENSG00000282801(gene)|ensembl:ENST00000496168(transcript)|ensembl:ENST00000632205(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:WKovn0mvryvDbJqn6iNbiFvN+rw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01615 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1053880|ensembl:ENSP00000393492|uniprotkb:A0A0A0MTQ6|uniprotkb:P01616|uniprotkb:P01617|uniprotkb:P06309 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kvd28_human(display_long)|uniprotkb:IGKV2D-28(gene name)|psi-mi:IGKV2D-28(display_short)|uniprotkb:Ig kappa chain V-II region FR(gene name synonym)|uniprotkb:Ig kappa chain V-II region GM607(gene name synonym)|uniprotkb:Ig kappa chain V-II region MIL(gene name synonym)|uniprotkb:Ig kappa chain V-II region TEW(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000242534(gene)|ensembl:ENST00000453166(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1DH4|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:lSXOgurkuk3p5y9OwC0AdI77X2U9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01593 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-20594941|uniprotkb:P01613|uniprotkb:P80362|uniprotkb:A0A0B4J1U0|uniprotkb:P01595|uniprotkb:P01605|uniprotkb:P01607|uniprotkb:P01608|uniprotkb:P01609|ensembl:ENSP00000374800 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kvd33_human(display_long)|uniprotkb:Ig kappa chain V-I region AG(gene name synonym)|uniprotkb:Ig kappa chain V-I region Bi(gene name synonym)|uniprotkb:Ig kappa chain V-I region Lay(gene name synonym)|uniprotkb:Ig kappa chain V-I region Ni(gene name synonym)|uniprotkb:Ig kappa chain V-I region Rei(gene name synonym)|uniprotkb:Ig kappa chain V-I region Roy(gene name synonym)|uniprotkb:Ig kappa chain V-I region Scw(gene name synonym)|uniprotkb:Ig kappa chain V-I region WAT(gene name synonym)|uniprotkb:IGKV1D-33(gene name)|psi-mi:IGKV1D-33(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000239975(gene)|ensembl:ENST00000390265(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1AR2|rcsb pdb:1BWW|rcsb pdb:1REI|rcsb pdb:1WTL|rcsb pdb:4L1H|rcsb pdb:5XP1|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:+8FNYvbRPCc9GI9G4Tf+BdsBnd49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9UNM6 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:iOxE62MMeGx+aqsrir/LukJqeho9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9ULX6 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9HCU9 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-714781|uniprotkb:Q6IAI2|ensembl:ENSP00000353042 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:brms1_human(display_long)|uniprotkb:BRMS1(gene name)|psi-mi:BRMS1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000174744(gene)|ensembl:ENST00000359957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR013907(Sds3-like)|rcsb pdb:2XUS|rcsb pdb:4AUV|reactome:R-HSA-3214815|reactome:R-HSA-9679191|refseq:NP_056214.1|dip:DIP-24250N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:kuaR4dVP6xzSOMHwSd+CDrLU/uo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9H0D6 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-372110|uniprotkb:Q3L8N4|uniprotkb:Q6KGZ9|uniprotkb:Q9BQL1|uniprotkb:Q9NTW0|uniprotkb:Q9NXS6|uniprotkb:Q9UL53|ensembl:ENSP00000366396 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:xrn2_human(display_long)|uniprotkb:XRN2(gene name)|psi-mi:XRN2(display_short)|uniprotkb:DHM1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_036387.2|refseq:NP_001304889.1|ensembl:ENSG00000088930(gene)|ensembl:ENST00000377191(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|mint:Q9H0D6|reactome:R-HSA-390471|reactome:R-HSA-6791226|dip:DIP-31166N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Ui0NiU+fGe68hK5CYTolkhioQbQ9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9BZK7 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-765729|uniprotkb:Q14DC3|uniprotkb:Q9H2I1|uniprotkb:Q9H9A1|uniprotkb:D3DNQ9|ensembl:ENSP00000263964|ensembl:ENSP00000387849|ensembl:ENSP00000405574|ensembl:ENSP00000413251|ensembl:ENSP00000501274 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tbl1r_human(display_long)|uniprotkb:Transducin beta-like 1X-related protein 1(gene name synonym)|uniprotkb:Nuclear receptor corepressor/HDAC3 complex subunit TBLR1(gene name synonym)|uniprotkb:TBL1-related protein 1(gene name synonym)|uniprotkb:TBL1XR1(gene name)|psi-mi:TBL1XR1(display_short)|uniprotkb:IRA1(gene name synonym)|uniprotkb:TBLR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_078941.2|refseq:XP_011511443.1|refseq:XP_011511444.1|refseq:XP_011511445.1|refseq:NP_001308123.1|refseq:NP_001308124.1|refseq:NP_001308122.1|refseq:XP_005247832.1|refseq:XP_006713809.1|refseq:XP_016862674.1|dip:DIP-34582N|ensembl:ENSG00000177565(gene)|ensembl:ENST00000422442(transcript)|ensembl:ENST00000352800(transcript)|ensembl:ENST00000430069(transcript)|ensembl:ENST00000457928(transcript)|ensembl:ENST00000673974(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9BZK7|rcsb pdb:4LG9|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Sr6jJZT7jdfR/ps1xK1ySq9/TuI9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9BVP2 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-641642|uniprotkb:Q96SV6|uniprotkb:Q96SV7|uniprotkb:Q9UJY0|intact:EBI-2559594|intact:EBI-718302|uniprotkb:B2RDC1|uniprotkb:Q5PU80|intact:EBI-28973725|ensembl:ENSP00000395772 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:gnl3_human(display_long)|uniprotkb:Nucleolar GTP-binding protein 3(gene name synonym)|uniprotkb:Nucleostemin(gene name synonym)|uniprotkb:E2-induced gene 3 protein(gene name synonym)|uniprotkb:Novel nucleolar protein 47(gene name synonym)|uniprotkb:GNL3(gene name)|psi-mi:GNL3(display_short)|uniprotkb:E2IG3(gene name synonym)|uniprotkb:NS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENST00000394799|ensembl:ENSP00000378278|ensembl:ENSP00000395772|refseq:NP_055181.3|refseq:NP_996561.1|refseq:NP_996562.1|ensembl:ENSG00000163938(gene)|ensembl:ENST00000418458(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030496"(midbody)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR027417|interpro:IPR030378|mint:Q9BVP2|reactome:R-HSA-6791226 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:c1DgvQoZ51edxvnCa6GFhfNRR7M9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q92945 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_003676.2|ensembl:ENSG00000088247(gene)|ensembl:ENST00000398148(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:hlybJllTqSgPgtwwz3kc12zDYh49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q5T750 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2563033|ensembl:ENSP00000357764|uniprotkb:O14634 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:xp32_human(display_long)|uniprotkb:XP32(gene name)|psi-mi:XP32(display_short)|uniprotkb:C1orf68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001019850.1|ensembl:ENSG00000198854(gene)|ensembl:ENST00000368775(transcript)|go:"GO:0008544"(epidermis development)|interpro:IPR026078|mint:Q5T750 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:QHKngjyz/pqUrpu1XJ8NINDtmm49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q15370 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q12905 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q07021 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q01130 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P78527 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P78347 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P62854 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P52272 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-486809|uniprotkb:Q9Y492|uniprotkb:Q15584|uniprotkb:Q8WZ44|uniprotkb:Q96H56|uniprotkb:Q9BWL9|intact:EBI-28985795|ensembl:ENSP00000325376 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hnrpm_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005959.2|refseq:NP_112480.2|ensembl:ENSG00000099783(gene)|ensembl:ENST00000325495(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:P52272|rcsb pdb:2DGV|rcsb pdb:2DH9|rcsb pdb:2DO0|rcsb pdb:2OT8|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-29336N|ensembl:ENSP00000325376|ensembl:ENST00000348943|ensembl:ENSP00000325732 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:5FnCgrz0xltEkgw3yh70KP2jz5g9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P50750 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P35030 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P26373 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356849|uniprotkb:Q3KQT8|uniprotkb:Q9BPX0|uniprotkb:Q567Q8|uniprotkb:B4DLX3|uniprotkb:F5H1S2|ensembl:ENSP00000307889|ensembl:ENSP00000376811|ensembl:ENSP00000455009 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rl13_human(display_long)|uniprotkb:RPL13(gene name)|psi-mi:RPL13(display_short)|uniprotkb:BBC1(gene name synonym)|uniprotkb:Breast basic conserved protein 1(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL13(gene name synonym)|uniprotkb:OK/SW-cl.46(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000968.2|refseq:NP_150254.1|refseq:NP_001230059.1|refseq:NP_001230060.1|ensembl:ENSG00000167526(gene)|ensembl:ENST00000311528(transcript)|ensembl:ENST00000393099(transcript)|ensembl:ENST00000567815(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0060348"(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P26373|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-192823 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:2SZ+AEe41Ystwj9t9I0Z1cZ5GQ49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P26368 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-742339|uniprotkb:Q96HC5|intact:EBI-946034|ensembl:ENSP00000307863 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:u2af2_human(display_long)|uniprotkb:U2AF2(gene name)|psi-mi:U2AF2(display_short)|uniprotkb:U2AF65(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N go:"GO:0005634"(nucleus)|refseq:NP_001012496.1|refseq:NP_009210.1|ensembl:ENSG00000063244(gene)|ensembl:ENST00000308924(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|rcsb pdb:2HZC|rcsb pdb:2M0G|rcsb pdb:2U2F|rcsb pdb:2YH0|rcsb pdb:2YH1|rcsb pdb:3VAF|rcsb pdb:3VAG|rcsb pdb:3VAH|rcsb pdb:3VAI|rcsb pdb:3VAJ|rcsb pdb:3VAK|rcsb pdb:3VAL|rcsb pdb:3VAM|rcsb pdb:4FXW|rcsb pdb:4TU7|rcsb pdb:4TU8|rcsb pdb:4TU9|rcsb pdb:5EV1|rcsb pdb:5EV2|rcsb pdb:5EV3|rcsb pdb:5EV4|rcsb pdb:5W0G|rcsb pdb:5W0H|rcsb pdb:6TR0|rcsb pdb:6XLV|rcsb pdb:6XLW|rcsb pdb:6XLX|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:2G4B|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26368|rcsb pdb:1JMT|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:1U2F|go:"GO:0005654"(nucleoplasm)|dip:DIP-2154N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:HBYwOej94CoGGN7vPbk0AnbO61Q9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P25705 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P21817 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1221290|uniprotkb:Q16314|uniprotkb:Q16368|uniprotkb:Q9NPK1|uniprotkb:Q9P1U4|ensembl:ENSP00000352608 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ryr1_human(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:RYDR(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000531.2|refseq:NP_001036188.1|dip:DIP-29708N|ensembl:ENSG00000196218(gene)|ensembl:ENST00000359596(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031674"(I band)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:6UHI|rcsb pdb:6UHS|reactome:R-HSA-2672351|reactome:R-HSA-5578775 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:WHlPtd5++5f+9GX0IGshsqJCOTg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P14678 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-372458|uniprotkb:Q15490|uniprotkb:Q9UIS5|uniprotkb:Q6IB35|ensembl:ENSP00000412566 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rsmb_human(display_long)|uniprotkb:Sm protein B/B'(gene name synonym)|uniprotkb:SNRPB(gene name)|psi-mi:SNRPB(display_short)|uniprotkb:COD(gene name synonym)|uniprotkb:SNRPB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_003082.1|refseq:NP_937859.1|ensembl:ENSG00000125835(gene)|ensembl:ENST00000438552(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007420"(brain development)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:1990446"(U1 snRNP binding)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN)|mint:P14678|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|dip:DIP-31239N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:zm9vJCpHG8w5iKErbOphUDCXTPk9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P13639 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P12956 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P10599 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|uniprotkb:Q9UDG5|intact:EBI-1042712|ensembl:ENSP00000363641 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|ensembl:ENSG00000136810(gene)|ensembl:ENST00000374517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:1W1C|rcsb pdb:1W1E|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P08621 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1049228|uniprotkb:P78493|uniprotkb:P78494|uniprotkb:Q15364|uniprotkb:Q15686|uniprotkb:Q15687|uniprotkb:Q15689|uniprotkb:Q99377|uniprotkb:Q9UE45|uniprotkb:Q9UE46|uniprotkb:Q9UE47|uniprotkb:Q9UE48|uniprotkb:Q9UFQ6|intact:EBI-3190943|uniprotkb:B3KUA3|ensembl:ENSP00000472998 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ru17_human(display_long)|uniprotkb:SNRNP70(gene name)|psi-mi:SNRNP70(display_short)|uniprotkb:RPU1(gene name synonym)|uniprotkb:U1AP1(gene name synonym)|uniprotkb:RNPU1Z(gene name synonym)|uniprotkb:SNRP70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_003080.2|refseq:NP_001287998.1|ensembl:ENSG00000104852(gene)|ensembl:ENST00000598441(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:1904715"(negative regulation of chaperone-mediated autophagy)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR022023|interpro:IPR034143|interpro:IPR035979|mint:P08621|rcsb pdb:2L5I|rcsb pdb:2L5J|rcsb pdb:3CW1|rcsb pdb:3PGW|rcsb pdb:4PJO|rcsb pdb:4PKD|rcsb pdb:6QX9|rcsb pdb:7B0Y|reactome:R-HSA-72163|dip:DIP-29406N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:/P72B69q5f0TX4vTr4GuRrtgiRM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P04406 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O75525 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O14561 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1246261|uniprotkb:Q9UNV1|uniprotkb:B2R4M1|ensembl:ENSP00000007516|ensembl:ENSP00000458770 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:acpm_human(display_long)|uniprotkb:NDUFAB1(gene name)|psi-mi:NDUFAB1(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 9.6 kDa subunit(gene name synonym)|uniprotkb:CI-SDAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004994.1|ensembl:ENSG00000004779(gene)|ensembl:ENST00000007516(transcript)|ensembl:ENST00000570319(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|rcsb pdb:2DNW|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|rcsb pdb:6ODD|rcsb pdb:7A5H|rcsb pdb:7A5J|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7|reactome:R-HSA-389661|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-77289 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:I3NqGP/VaZP/6cwDFwVIgmu8lP89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O00712 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-10963452|ensembl:ENSP00000370346|uniprotkb:Q6ZNF9|uniprotkb:Q63HM5|uniprotkb:Q5VW29|uniprotkb:Q96J45|uniprotkb:O00166|uniprotkb:H7BYE8|uniprotkb:G3V1P1|uniprotkb:Q12858 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:nfib_human(display_long)|uniprotkb:NFIB(gene name)|psi-mi:NFIB(display_short)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:Nuclear factor I/B(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001177666.1|refseq:NP_001177667.1|refseq:NP_001269716.1|refseq:NP_005587.2|ensembl:ENSG00000147862(gene)|ensembl:ENST00000380959(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009617"(response to bacterium)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0030902"(hindbrain development)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0060689"(cell differentiation involved in salivary gland development)|go:"GO:0061141"(lung ciliated cell differentiation)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000791"(negative regulation of mesenchymal cell proliferation involved in lung development)|go:"GO:2000795"(negative regulation of epithelial cell proliferation involved in lung morphogenesis)|interpro:IPR000647(CTF/NF-I)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR019548|interpro:IPR019739|interpro:IPR020604|reactome:R-HSA-73980|reactome:R-HSA-749476|dip:DIP-61433N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:p8fys7dLTTxec3i2H14zfniMVaY9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9Y5Q8 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1045409|uniprotkb:Q8N2U7|uniprotkb:Q8N857|uniprotkb:Q96GD9|uniprotkb:Q9H4P2|uniprotkb:A6NI44|uniprotkb:A6NJB9|uniprotkb:Q5T7U2|uniprotkb:Q5T7U3|intact:EBI-2556713|ensembl:ENSP00000361169 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tf3c5_human(display_long)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:GTF3C5(gene name)|psi-mi:GTF3C5(display_short)|uniprotkb:CDABP0017(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001116295.1|refseq:NP_036219.2|ensembl:ENSG00000148308(gene)|ensembl:ENST00000372097(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q9Y5Q8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|refseq:NP_001273638.1|dip:DIP-50823N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Cb1wPs3qn4+Up/g7WgOMDEFtp+M9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9Y4Z0 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-372521|ensembl:ENSP00000469468 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:lsm4_human(display_long)|uniprotkb:Glycine-rich protein(gene name synonym)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_036453.1|ensembl:ENSG00000130520(gene)|ensembl:ENST00000593829(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033962"(P-body assembly)|go:"GO:0042731"(PH domain binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0043005"(neuron projection)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|dip:DIP-31209N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:FlaQveuBbixGvfX47pCm26xscT09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9Y2W1 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634|ensembl:ENSP00000433825 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005110.2|ensembl:ENSG00000054118(gene)|ensembl:ENST00000354618(transcript)|ensembl:ENST00000469141(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026667|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|refseq:NP_001308400.1|refseq:NP_001308402.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9UNE7 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:h4QyIM0TptgkQppPUgiKn68XjP49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9UN37 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1171942|uniprotkb:Q8TF07|uniprotkb:Q9UI03|uniprotkb:Q9Y582|uniprotkb:B2RCB7|ensembl:ENSP00000254950 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:vps4a_human(display_long)|uniprotkb:VPS4-1(gene name synonym)|uniprotkb:Protein SKD2(gene name synonym)|uniprotkb:VPS4A(gene name)|psi-mi:VPS4A(display_short)|uniprotkb:VPS4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_037377.1|ensembl:ENSG00000132612(gene)|ensembl:ENST00000254950(transcript)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009838"(abscission)|go:"GO:0010008"(endosome membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072319"(vesicle uncoating)|go:"GO:0090543"(Flemming body)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1903902"(positive regulation of viral life cycle)|go:"GO:1904896"(ESCRT complex disassembly)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569|mint:Q9UN37|rcsb pdb:1YXR|rcsb pdb:2JQ9|rcsb pdb:2K3W|reactome:R-HSA-162588|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9668328|interpro:IPR031255|dip:DIP-44585N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:kr3zmre/ELTm2b/fCytp8IlBUhs9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9UKN8 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1237240|uniprotkb:Q5VZJ7|ensembl:ENSP00000361219 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tf3c4_human(display_long)|uniprotkb:GTF3C4(gene name)|psi-mi:GTF3C4(display_short)|uniprotkb:Transcription factor IIIC subunit delta(gene name synonym)|uniprotkb:TF3C-delta(gene name synonym)|uniprotkb:Transcription factor IIIC 90 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_036336.2|ensembl:ENSG00000125484(gene)|ensembl:ENST00000372146(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR024761|interpro:IPR024764|interpro:IPR036322|interpro:IPR044230|mint:Q9UKN8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:OFldz80WMs7KQ59Of0rkkj80lyc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9UHX1 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9UGM3 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1044970|uniprotkb:Q59EX0|uniprotkb:Q5JR26|uniprotkb:Q6MZN4|uniprotkb:Q96DU4|uniprotkb:Q9UGM2|uniprotkb:Q9UJ57|uniprotkb:Q9UKJ4|uniprotkb:Q9Y211|uniprotkb:Q9Y4V9|uniprotkb:A6NDG4|uniprotkb:A6NDJ5|uniprotkb:A8E4R5|uniprotkb:B1ARE7|uniprotkb:B1ARE8|uniprotkb:B1ARE9|uniprotkb:B1ARF0|uniprotkb:B7Z8Y2|uniprotkb:F8WEF7|ensembl:ENSP00000357905|ensembl:ENSP00000484603|ensembl:ENSP00000498825 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dmbt1_human(display_long)|uniprotkb:Glycoprotein 340(gene name synonym)|uniprotkb:Surfactant pulmonary-associated D-binding protein(gene name synonym)|uniprotkb:Hensin(gene name synonym)|uniprotkb:DMBT1(gene name)|psi-mi:DMBT1(display_short)|uniprotkb:GP340(gene name synonym)|uniprotkb:Salivary agglutinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004397.2|refseq:NP_015568.2|refseq:NP_060049.2|refseq:XP_011537690.1|refseq:XP_011537693.1|refseq:XP_011537707.1|refseq:NP_001307573.1|dip:DIP-50763N|ensembl:ENSG00000187908(gene)|ensembl:ENST00000368909(transcript)|ensembl:ENST00000619379(transcript)|ensembl:ENST00000652446(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035375"(zymogen binding)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042494"(detection of bacterial lipoprotein)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1904399"(heparan sulfate binding)|interpro:IPR000859(CUB)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001507(Endoglin/CD105 antigen)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR017977|interpro:IPR035914|interpro:IPR036772|interpro:IPR042235|mint:Q9UGM3|rcsb pdb:6SA4|rcsb pdb:6SA5|rcsb pdb:6SAN|reactome:R-HSA-5683826 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:A0Aw2F/rHW8mFmPDg4xOTy8NGzg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9NWZ5 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2466660|ensembl:ENSP00000346155|uniprotkb:Q9H3Z2|uniprotkb:Q8N524|uniprotkb:Q70AQ5|uniprotkb:Q5JWV0|uniprotkb:B7Z8N2 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:uckl1_human(display_long)|uniprotkb:F538(orf name)|uniprotkb:UCKL1(gene name)|psi-mi:UCKL1(display_short)|uniprotkb:URKL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000198276(gene)|ensembl:ENST00000354216(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043097"(pyrimidine nucleoside salvage)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|interpro:IPR029933|mint:Q9NWZ5|reactome:R-HSA-73614|refseq:NP_060329.2|refseq:NP_001180308.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:FkKO/bZUZfOV2Fe8iGuOzC+Stpg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9BSV6 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-11017932|uniprotkb:B0V3J1|uniprotkb:A6NNB1|uniprotkb:Q9H6H5|uniprotkb:Q9BVT1|ensembl:ENSP00000305524|ensembl:ENSP00000379667|ensembl:ENSP00000379671|ensembl:ENSP00000397402|ensembl:ENSP00000400743|ensembl:ENSP00000477766|ensembl:ENSP00000478156|ensembl:ENSP00000478622|ensembl:ENSP00000479576|ensembl:ENSP00000479654|ensembl:ENSP00000480422|ensembl:ENSP00000480503|ensembl:ENSP00000480899|ensembl:ENSP00000480964|ensembl:ENSP00000481068|ensembl:ENSP00000481374|ensembl:ENSP00000481639|ensembl:ENSP00000482084|ensembl:ENSP00000482527|ensembl:ENSP00000483266|ensembl:ENSP00000483436|ensembl:ENSP00000484225|ensembl:ENSP00000484465|ensembl:ENSP00000484694|ensembl:ENSP00000484865|ensembl:ENSP00000484964 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:sen34_human(display_long)|uniprotkb:TSEN34(gene name)|psi-mi:TSEN34(display_short)|uniprotkb:LENG5(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 5(gene name synonym)|uniprotkb:SEN34(gene name synonym)|uniprotkb:tRNA-intron endonuclease Sen34(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001070914.1|refseq:NP_001269261.1|refseq:NP_076980.2|refseq:XP_011525596.1|refseq:XP_011525597.1|ensembl:ENSG00000170892(gene)|ensembl:ENSG00000273896(gene)|ensembl:ENSG00000274078(gene)|ensembl:ENSG00000274129(gene)|ensembl:ENSG00000274672(gene)|ensembl:ENSG00000274796(gene)|ensembl:ENSG00000275165(gene)|ensembl:ENSG00000278605(gene)|ensembl:ENSG00000278622(gene)|ensembl:ENSG00000278712(gene)|ensembl:ENST00000302937(transcript)|ensembl:ENST00000396383(transcript)|ensembl:ENST00000396388(transcript)|ensembl:ENST00000429671(transcript)|ensembl:ENST00000455798(transcript)|ensembl:ENST00000611560(transcript)|ensembl:ENST00000611798(transcript)|ensembl:ENST00000612236(transcript)|ensembl:ENST00000612393(transcript)|ensembl:ENST00000613310(transcript)|ensembl:ENST00000613712(transcript)|ensembl:ENST00000613888(transcript)|ensembl:ENST00000614948(transcript)|ensembl:ENST00000614984(transcript)|ensembl:ENST00000615000(transcript)|ensembl:ENST00000615079(transcript)|ensembl:ENST00000615900(transcript)|ensembl:ENST00000615975(transcript)|ensembl:ENST00000616063(transcript)|ensembl:ENST00000616209(transcript)|ensembl:ENST00000617149(transcript)|ensembl:ENST00000617902(transcript)|ensembl:ENST00000618135(transcript)|ensembl:ENST00000619994(transcript)|ensembl:ENST00000622524(transcript)|ensembl:ENST00000622538(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0016829"(lyase activity)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR016690(tRNA-splicing endonuclease, SEN34 subunit)|interpro:IPR036167|rcsb pdb:6Z9U|reactome:R-HSA-6784531 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:4uEnLuOfSUb8jpuApGOMyuNgxCo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9BQA1 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:0q4wunYtHalObC8r1wphhelIpr49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q99873 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q96T37 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2514922|ensembl:ENSP00000358799|ensembl:ENSP00000483133|uniprotkb:Q96SC9|uniprotkb:Q5D058|uniprotkb:Q96SD0|uniprotkb:Q5T613|uniprotkb:Q96SC5|uniprotkb:Q96T38|uniprotkb:Q9BRA5|uniprotkb:Q96SC6|uniprotkb:Q9H9Y0|uniprotkb:Q96PE4|uniprotkb:Q9H6R8|uniprotkb:Q4V760|uniprotkb:A1A693|uniprotkb:Q3ZB86|uniprotkb:Q86VW9 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rbm15_human(display_long)|uniprotkb:RBM15(gene name)|psi-mi:RBM15(display_short)|uniprotkb:OTT(gene name synonym)|uniprotkb:OTT1(gene name synonym)|uniprotkb:RNA-binding motif protein 15(gene name synonym)|uniprotkb:One-twenty two protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000162775(gene)|ensembl:ENST00000369784(transcript)|ensembl:ENST00000618772(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0038163"(thrombopoietin-mediated signaling pathway)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0048536"(spleen development)|go:"GO:0060674"(placenta blood vessel development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034470|interpro:IPR034472|interpro:IPR034473|interpro:IPR035979|mint:Q96T37|go:"GO:0060412"(ventricular septum morphogenesis)|refseq:NP_001188474.1|refseq:NP_073605.4|ensembl:ENSP00000358799|ensembl:ENST00000487146|ensembl:ENSP00000473552|ensembl:ENST00000602849|ensembl:ENSP00000473638|ensembl:ENSP00000483133|ensembl:ENST00000652342|ensembl:ENSP00000498328|ensembl:ENST00000652747|ensembl:ENSP00000498634 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:t7EkMQbmDxPl/X8yPkBi1zCywac9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q92466 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1176171|uniprotkb:Q76E54|uniprotkb:Q76E55|uniprotkb:Q76E56|uniprotkb:Q76E57|uniprotkb:B2R875|ensembl:ENSP00000256996 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ddb2_human(display_long)|uniprotkb:Damage-specific DNA-binding protein 2(gene name synonym)|uniprotkb:DDB p48 subunit(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 2(gene name synonym)|uniprotkb:DDB2(gene name)|psi-mi:DDB2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000098.1|refseq:NP_001287663.1|ensembl:ENSG00000134574(gene)|ensembl:ENST00000256996(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0009411"(response to UV)|go:"GO:0030054"(cell junction)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR033312|interpro:IPR036322|rcsb pdb:3EI4|rcsb pdb:3I7L|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6796648|reactome:R-HSA-8951664|dip:DIP-36670N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:HkT35Q/boNG3Gc5ZH4PzTwrMebU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q8WZA2 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-948476|ensembl:ENSP00000380271|uniprotkb:O95636|uniprotkb:Q8IXK6|uniprotkb:Q8TAA4|uniprotkb:B2R7R3|uniprotkb:B7Z912|uniprotkb:B7Z283|uniprotkb:B7Z3T6 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rpgf4_human(display_long)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short)|uniprotkb:CGEF2(gene name synonym)|uniprotkb:EPAC2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001269828.1|refseq:NP_001269829.1|refseq:NP_001269830.1|ensembl:ENSG00000091428(gene)|ensembl:ENST00000397081(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|reactome:R-HSA-354192|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|refseq:NP_001093867.1|refseq:NP_008954.2|refseq:XP_006712268.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:cYq6CkJ34txlv5XggTyHhvQvcEw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q8WWY3 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1567797|uniprotkb:Q8N7F9|uniprotkb:Q9H271|uniprotkb:Q9Y439|uniprotkb:Q17RB4|intact:EBI-10177194|uniprotkb:F1T0A5|uniprotkb:E7ESA8|uniprotkb:F1T0A4|ensembl:ENSP00000324122|ensembl:ENSP00000483929 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:prp31_human(display_long)|uniprotkb:Pre-mRNA-processing factor 31(gene name synonym)|uniprotkb:U4/U6 snRNP 61 kDa protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-99(gene name synonym)|uniprotkb:PRPF31(gene name)|psi-mi:PRPF31(display_short)|uniprotkb:PRP31(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:XP_006723200.1|refseq:NP_056444.3|ensembl:ENSG00000105618(gene)|ensembl:ENSG00000275885(gene)|ensembl:ENST00000321030(transcript)|ensembl:ENST00000613693(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005690"(U4atac snRNP)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR012976(NOSIC)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070990"(snRNP binding)|interpro:IPR019175|interpro:IPR027105|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071166"(ribonucleoprotein complex localization)|interpro:IPR036070|interpro:IPR042239|mint:Q8WWY3|rcsb pdb:2OZB|rcsb pdb:3JCR|rcsb pdb:3SIU|rcsb pdb:3SIV|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:NsXY3tY7Y2EEK8rxoisqlfpzuf89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q8IX05 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-14259393|ensembl:ENSP00000259053|uniprotkb:A8K5G4|uniprotkb:B4E2T9|uniprotkb:Q15009 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:cd302_human(display_long)|uniprotkb:CD302(gene name)|psi-mi:CD302(display_short)|uniprotkb:C-type lectin BIMLEC(gene name synonym)|uniprotkb:C-type lectin domain family 13 member A(gene name synonym)|uniprotkb:CLEC13A(gene name synonym)|uniprotkb:DCL1(gene name synonym)|uniprotkb:DEC205-associated C-type lectin 1(gene name synonym)|uniprotkb:KIAA0022(gene name synonym)|uniprotkb:Type I transmembrane C-type lectin receptor DCL-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000241399(gene)|ensembl:ENST00000259053(transcript)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006909"(phagocytosis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030175"(filopodium)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|rcsb pdb:2NAN|go:"GO:0016020"(membrane)|refseq:NP_001185692.1|refseq:NP_055695.2 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:kcfdSSzh0trUfhk8ZV4ciy6OexI9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q8IV04 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-10261452|uniprotkb:G3V1D6|ensembl:ENSP00000443654 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tb10c_human(display_long)|uniprotkb:TBC1D10C(gene name)|psi-mi:TBC1D10C(display_short)|uniprotkb:TBC1 domain family member 10C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001243437.1|refseq:NP_940919.1|refseq:XP_006718601.1|refseq:XP_006718602.1|refseq:XP_006718603.1|ensembl:ENSG00000175463(gene)|ensembl:ENST00000542590(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|reactome:R-HSA-6798695|reactome:R-HSA-8854214|dip:DIP-60264N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:GgmTrnBwUHrZks4qEWHv9PmgO1E9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q6NXT2 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2868501|uniprotkb:E9P281|ensembl:ENSP00000339835 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:h3c_human(display_long)|uniprotkb:H3-5(gene name)|psi-mi:H3-5(display_short)|uniprotkb:H3F3C(gene name synonym)|uniprotkb:Histone H3.5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001013721.2|go:"GO:0006997"(nucleus organization)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0007566"(embryo implantation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:1902340"(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q6NXT2|rcsb pdb:2PUY|rcsb pdb:3KV4|rcsb pdb:4Z5T|rcsb pdb:5BWN|rcsb pdb:5BWO|rcsb pdb:5F6K|rcsb pdb:5I3L|rcsb pdb:6OI3|ensembl:ENSG00000188375(gene)|ensembl:ENST00000340398(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001740"(Barr body)|go:"GO:0005634"(nucleus) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:d8jgPwPl7fXRRpWh+ON9tiyrgnY9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q63HM1 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-13286382|ensembl:ENSP00000386890|uniprotkb:A2RUB3 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kfa_human(display_long)|uniprotkb:AFMID(gene name)|psi-mi:AFMID(display_short)|uniprotkb:Arylformamidase(gene name synonym)|uniprotkb:N-formylkynurenine formamidase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000183077(gene)|ensembl:ENST00000409257(transcript)|go:"GO:0004061"(arylformamidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|interpro:IPR013094(Alpha/beta hydrolase fold-3)|interpro:IPR027519|interpro:IPR029058|reactome:R-HSA-71240|refseq:NP_001010982.2|refseq:NP_001138998.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:+tis9xp48Ye+7YUzcYq4/pJOSyQ9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q5SNV9 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-20595058|uniprotkb:Q8NDA9|uniprotkb:Q8NDF3|ensembl:ENSP00000414909 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ca167_human(display_long)|uniprotkb:C1orf167(gene name)|psi-mi:C1orf167(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001010881.1|ensembl:ENSG00000215910(gene)|ensembl:ENST00000433342(transcript)|interpro:IPR031473 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:+cmBEGDJTqSSR7G63bQE+Hwr57M9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q5D862 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2952722|ensembl:ENSP00000373370|uniprotkb:Q9H4U1 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:fila2_human(display_long)|uniprotkb:FLG2(gene name)|psi-mi:FLG2(display_short)|uniprotkb:IFPS(gene name synonym)|uniprotkb:Intermediate filament-associated and psoriasis-susceptibility protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSP00000373370|ensembl:ENSG00000143520(gene)|ensembl:ENST00000388718(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003303(Filaggrin)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR034325|mint:Q5D862|reactome:R-HSA-6798695|go:"GO:0036457"(keratohyalin granule)|refseq:NP_001014364.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:b0VRX4uLQtUVeodRvtwEWgfmzZc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q16650 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1047158|ensembl:ENSP00000374205|uniprotkb:Q14DC5|uniprotkb:Q53TH0|uniprotkb:B2R6G5|uniprotkb:Q56A81|uniprotkb:B0AZS4 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tbr1_human(display_long)|uniprotkb:TES-56(gene name synonym)|uniprotkb:TBR1(gene name)|psi-mi:TBR1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006584.1|ensembl:ENSG00000136535(gene)|ensembl:ENST00000389554(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1902667"(regulation of axon guidance)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021764"(amygdala development)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030902"(hindbrain development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR032385|interpro:IPR036960|mint:Q16650 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:qD1euHkX/welvC2klFM95IiAiWE9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q16576 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q15773 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q15365 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q14103 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q13410 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2372803|uniprotkb:Q4VAN4|uniprotkb:Q9H458|uniprotkb:Q4VAN3|ensembl:ENSP00000244513|ensembl:ENSP00000507193 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:bt1a1_human(display_long)|uniprotkb:BTN1A1(gene name)|psi-mi:BTN1A1(display_short)|uniprotkb:BTN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001723.2|ensembl:ENSG00000124557(gene)|ensembl:ENST00000244513(transcript)|ensembl:ENST00000684113(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037958|interpro:IPR043136|reactome:R-HSA-8851680 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:3vJxfUEU8CgKp6iDHJvVC/2KNNU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q13148 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q08554 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2371346|uniprotkb:Q9HB01|ensembl:ENSP00000257198 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dsc1_human(display_long)|uniprotkb:DSC1(gene name)|psi-mi:DSC1(display_short)|uniprotkb:CDHF1(gene name synonym)|uniprotkb:Desmosomal glycoprotein 2/3(gene name synonym)|uniprotkb:Cadherin family member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004939.1|refseq:NP_077739.1|ensembl:ENSG00000134765(gene)|ensembl:ENST00000257198(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030057"(desmosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|rcsb pdb:5IRY|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:dxtPfdDnZFaelPwT5bV8k/ZobSw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q05707 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2528599|uniprotkb:B2RU07|uniprotkb:O00260|uniprotkb:O00261|uniprotkb:O00262|uniprotkb:Q05708|uniprotkb:Q5XJ18|uniprotkb:Q96C67|uniprotkb:Q9UDF6|ensembl:ENSP00000297848 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:coea1_human(display_long)|uniprotkb:COL14A1(gene name)|psi-mi:COL14A1(display_short)|uniprotkb:UND(gene name synonym)|uniprotkb:Undulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:XP_016869298.1|refseq:NP_066933.1|refseq:XP_005251116.1|refseq:XP_006716714.1|ensembl:ENSG00000187955(gene)|ensembl:ENST00000297848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005596"(collagen type XIV trimer)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001791(Laminin G)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036465|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8948216 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:8eQ55YOi3IK4OWPI57s3ak2q4bg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q01844 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P83731 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P63173 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-359141|uniprotkb:P23411|uniprotkb:B2R5A8|ensembl:ENSP00000309830|ensembl:ENSP00000390279|ensembl:ENSP00000434243 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rl38_human(display_long)|uniprotkb:RPL38(gene name)|psi-mi:RPL38(display_short)|uniprotkb:Large ribosomal subunit protein eL38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000990.1|refseq:NP_001030335.1|ensembl:ENSG00000172809(gene)|ensembl:ENST00000311111(transcript)|ensembl:ENST00000439590(transcript)|ensembl:ENST00000533498(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022618"(ribonucleoprotein complex assembly)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0033291"(eukaryotic 80S initiation complex)|go:"GO:0034463"(90S preribosome assembly)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0048318"(axial mesoderm development)|interpro:IPR002675(Ribosomal protein L38e)|interpro:IPR038464|mint:P63173|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:5AJ0|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:6kUSGJll3ldTTRzgVTSwBjgV19Y9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P63167 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P62318 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-372789|uniprotkb:P43331|uniprotkb:B5BU13|uniprotkb:B4DJP7|ensembl:ENSP00000215829|intact:EBI-10981086 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:smd3_human(display_long)|uniprotkb:SNRPD3(gene name)|psi-mi:SNRPD3(display_short)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004166.1|refseq:NP_001265585.1|ensembl:ENSG00000100028(gene)|ensembl:ENST00000215829(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|mint:P62318|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|rcsb pdb:7ABG|rcsb pdb:3VRI|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:3PGW|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|dip:DIP-31216N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:WkrSZVfVmSQrJYfy7mwp48xjsVA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P62263 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352783|ensembl:ENSP00000311028|ensembl:ENSP00000385425|uniprotkb:P06366|uniprotkb:Q5BJI0|uniprotkb:B2R5G5|uniprotkb:D3DQG5|ensembl:ENSP00000385958|ensembl:ENSP00000428509 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rs14_human(display_long)|uniprotkb:RPS14(gene name)|psi-mi:RPS14(display_short)|uniprotkb:Small ribosomal subunit protein uS11(gene name synonym)|uniprotkb:PRO2640(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000164587(gene)|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001020242.1|refseq:NP_005608.1|refseq:NP_001020241.1|ensembl:ENST00000312037(transcript)|ensembl:ENST00000401695(transcript)|ensembl:ENST00000407193(transcript)|ensembl:ENST00000521466(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P62263|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:ee3bJ5JYFaZXyCCRG9Wooopyz2o9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P61626 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355360|ensembl:ENSP00000261267|uniprotkb:P00695|uniprotkb:Q9UCF8|uniprotkb:Q13170 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:lysc_human(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:LZM(gene name synonym)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000090382(gene)|refseq:NP_000230.1|rcsb pdb:1GB7|rcsb pdb:1GB8|rcsb pdb:1GB9|rcsb pdb:1GBO|rcsb pdb:1GBW|rcsb pdb:1GBX|rcsb pdb:1GBY|rcsb pdb:1GBZ|rcsb pdb:1GDW|rcsb pdb:1GDX|rcsb pdb:1GE0|rcsb pdb:1GE1|rcsb pdb:1GE2|rcsb pdb:1GE3|rcsb pdb:1GE4|rcsb pdb:1GEV|rcsb pdb:1GEZ|rcsb pdb:1GF0|rcsb pdb:1GF3|rcsb pdb:1GF4|rcsb pdb:1GF5|rcsb pdb:1GF6|rcsb pdb:1GF7|rcsb pdb:1GF8|rcsb pdb:1GF9|rcsb pdb:1GFA|rcsb pdb:1GFE|rcsb pdb:1GFG|rcsb pdb:1GFH|rcsb pdb:1GFJ|rcsb pdb:1GFK|rcsb pdb:1GFR|rcsb pdb:1GFT|rcsb pdb:1GFU|rcsb pdb:1GFV|rcsb pdb:1HNL|rcsb pdb:1I1Z|rcsb pdb:1I20|rcsb pdb:1I22|rcsb pdb:1INU|rcsb pdb:1IOC|rcsb pdb:1IP1|rcsb pdb:1IP2|rcsb pdb:1IP3|rcsb pdb:1IP4|rcsb pdb:1IP5|rcsb pdb:1IP6|rcsb pdb:1IP7|rcsb pdb:1IWT|rcsb pdb:1IWU|rcsb pdb:1IWV|rcsb pdb:1IWW|rcsb pdb:1IWX|rcsb pdb:1IWY|rcsb pdb:1IWZ|rcsb pdb:1IX0|rcsb pdb:1IY3|rcsb pdb:1IY4|rcsb pdb:1JKA|rcsb pdb:1JKB|rcsb pdb:1JKC|rcsb pdb:1JKD|rcsb pdb:1JSF|rcsb pdb:1JWR|rcsb pdb:1LAA|rcsb pdb:1LHH|rcsb pdb:1LHI|rcsb pdb:1LHJ|rcsb pdb:1LHK|rcsb pdb:1LHL|rcsb pdb:1LHM|rcsb pdb:1LMT|rcsb pdb:1LOZ|rcsb pdb:1LYY|rcsb pdb:1LZ1|rcsb pdb:1LZ4|rcsb pdb:1LZ5|rcsb pdb:1LZ6|rcsb pdb:1LZR|rcsb pdb:1LZS|rcsb pdb:1OP9|rcsb pdb:1OUA|rcsb pdb:1OUB|rcsb pdb:1OUC|rcsb pdb:1OUD|rcsb pdb:1OUE|rcsb pdb:1OUF|rcsb pdb:1OUG|rcsb pdb:1OUH|rcsb pdb:1OUI|rcsb pdb:1OUJ|rcsb pdb:1QSW|rcsb pdb:1RE2|rcsb pdb:1REM|rcsb pdb:1REX|rcsb pdb:1REY|rcsb pdb:1REZ|rcsb pdb:1TAY|rcsb pdb:1TBY|rcsb pdb:1TCY|rcsb pdb:1TDY|rcsb pdb:1UBZ|rcsb pdb:5LVK|rcsb pdb:6LFH|reactome:R-HSA-6798695|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1W08|rcsb pdb:1WQM|rcsb pdb:1WQN|rcsb pdb:1WQO|rcsb pdb:1WQP|rcsb pdb:1WQQ|rcsb pdb:1WQR|rcsb pdb:1YAM|rcsb pdb:1YAN|rcsb pdb:1YAO|rcsb pdb:1YAP|rcsb pdb:1YAQ|rcsb pdb:207L|rcsb pdb:208L|rcsb pdb:2BQA|rcsb pdb:2BQB|rcsb pdb:2BQC|rcsb pdb:2BQD|rcsb pdb:2BQE|rcsb pdb:2BQF|rcsb pdb:2BQG|rcsb pdb:2BQH|rcsb pdb:2BQI|rcsb pdb:2BQJ|rcsb pdb:2BQK|rcsb pdb:2BQL|rcsb pdb:2BQM|rcsb pdb:2BQN|rcsb pdb:2BQO|rcsb pdb:2HEA|rcsb pdb:2HEB|rcsb pdb:2HEC|rcsb pdb:2HED|rcsb pdb:2HEE|rcsb pdb:2HEF|rcsb pdb:2LHM|rcsb pdb:2MEA|rcsb pdb:2MEB|rcsb pdb:2MEC|rcsb pdb:2MED|rcsb pdb:2MEE|rcsb pdb:2MEF|rcsb pdb:2MEG|rcsb pdb:2MEH|rcsb pdb:2MEI|rcsb pdb:2NWD|rcsb pdb:2ZIJ|rcsb pdb:2ZIK|rcsb pdb:2ZIL|rcsb pdb:2ZWB|rcsb pdb:3EBA|rcsb pdb:3FE0|rcsb pdb:3LHM|rcsb pdb:3LN2|rcsb pdb:4I0C|rcsb pdb:4ML7|rcsb pdb:4R0P|rcsb pdb:5LSH|rcsb pdb:1B5X|rcsb pdb:1B5Y|rcsb pdb:1B5Z|rcsb pdb:1B7L|rcsb pdb:1B7M|rcsb pdb:1B7N|rcsb pdb:1B7O|rcsb pdb:1B7P|rcsb pdb:1B7Q|rcsb pdb:1B7R|rcsb pdb:1B7S|rcsb pdb:1BB3|rcsb pdb:1BB4|rcsb pdb:1BB5|rcsb pdb:1C43|rcsb pdb:1C45|rcsb pdb:1C46|rcsb pdb:1C7P|rcsb pdb:1CJ6|rcsb pdb:1CJ7|rcsb pdb:1CJ8|ensembl:ENST00000261267(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003796"(lysozyme activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008152"(metabolic process)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019835"(cytolysis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|interpro:IPR030056|mint:P61626|rcsb pdb:133L|rcsb pdb:134L|rcsb pdb:1B5U|rcsb pdb:1B5V|rcsb pdb:1B5W|rcsb pdb:1CJ9|rcsb pdb:1CKC|rcsb pdb:1CKD|rcsb pdb:1CKF|rcsb pdb:1CKG|rcsb pdb:1CKH|rcsb pdb:1D6P|rcsb pdb:1D6Q|rcsb pdb:1DI3|rcsb pdb:1DI4|rcsb pdb:1DI5|rcsb pdb:1EQ4|rcsb pdb:1EQ5|rcsb pdb:1EQE|rcsb pdb:1GAY|rcsb pdb:1GAZ|rcsb pdb:1GB0|rcsb pdb:1GB2|rcsb pdb:1GB3|rcsb pdb:1GB5|rcsb pdb:1GB6 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:jydNN9yuU9EYvnth+kv115svRxw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P55072 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P51991 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P32119 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P27708 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P24752 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1051459|uniprotkb:B2R6H1|uniprotkb:G3XAB4|uniprotkb:Q96FG8|ensembl:ENSP00000265838 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:thil_human(display_long)|uniprotkb:Acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:T2(gene name synonym)|uniprotkb:ACAT1(gene name)|psi-mi:ACAT1(display_short)|uniprotkb:ACAT(gene name synonym)|uniprotkb:MAT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000010.1|ensembl:ENSG00000075239(gene)|ensembl:ENST00000265838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007420"(brain development)|go:"GO:0009725"(response to hormone)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016453"(C-acetyltransferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046356"(acetyl-CoA catabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072229"(metanephric proximal convoluted tubule development)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1902224"(ketone body metabolic process)|go:"GO:1902860"(propionyl-CoA biosynthetic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|rcsb pdb:2F2S|rcsb pdb:2IB7|rcsb pdb:2IB8|rcsb pdb:2IB9|rcsb pdb:2IBU|rcsb pdb:2IBW|rcsb pdb:2IBY|reactome:R-HSA-70895|reactome:R-HSA-77108|reactome:R-HSA-77111 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:UYAY+kDdcJqx/hrDFoXH9rgtm/E9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P23588 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P23246 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P04083 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:QKmqz+UsAof35B/so2qKLQjn2v09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P02788 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01594 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-15853604|ensembl:ENSP00000420020|ensembl:ENSP00000487732|uniprotkb:A0A087WZH9|uniprotkb:P01603 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kv133_human(display_long)|uniprotkb:IGKV1-33(gene name)|psi-mi:IGKV1-33(display_short)|uniprotkb:Ig kappa chain V-I region AU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Ka(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000242076(gene)|ensembl:ENSG00000282811(gene)|ensembl:ENST00000473726(transcript)|ensembl:ENST00000632835(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B0W|rcsb pdb:1JV5|rcsb pdb:1QP1|rcsb pdb:2Q20|rcsb pdb:3CDC|rcsb pdb:3CDF|rcsb pdb:3CDY|rcsb pdb:4K07|rcsb pdb:7CZQ|rcsb pdb:7CZU|rcsb pdb:7CZV|reactome:R-HSA-166663|reactome:R-HSA-173623|go:"GO:0005615"(extracellular space)|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|dip:DIP-58572N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:+8FNYvbRPCc9GI9G4Tf+BdsBnd49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01040 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O95817 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-747185|uniprotkb:Q3B763|uniprotkb:Q9NT20|uniprotkb:Q9P120|uniprotkb:A8K5L8|ensembl:ENSP00000358081 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:bag3_human(display_long)|uniprotkb:Bcl-2-associated athanogene 3(gene name synonym)|uniprotkb:Bcl-2-binding protein Bis(gene name synonym)|uniprotkb:Docking protein CAIR-1(gene name synonym)|uniprotkb:BAG3(gene name)|psi-mi:BAG3(display_short)|uniprotkb:BIS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004272.2|ensembl:ENSG00000151929(gene)|ensembl:ENST00000369085(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007420"(brain development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0021510"(spinal cord development)|go:"GO:0030018"(Z disc)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773|mint:O95817|reactome:R-HSA-3371453|go:"GO:0101031"(chaperone complex)|dip:DIP-41273N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Ld26VRSMJghXG/U98A76RijSDBc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O75643 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_054733.2|ensembl:ENSG00000144028(gene)|ensembl:ENST00000323853(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:XP_016859092.1|dip:DIP-31659N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O75190 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O60814 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O43809 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O43719 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:PttL+7D+505QAmcHRGNsc40haPY9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O43175 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O14744 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q99933 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1030678|uniprotkb:O75315|uniprotkb:Q14414|uniprotkb:Q96TG2|uniprotkb:Q9Y2V4|uniprotkb:Q53H32|uniprotkb:Q5VZE8|uniprotkb:Q5VZE9|uniprotkb:Q5VZF0|ensembl:ENSP00000489189 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:bag1_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:Bcl-2-associated athanogene 1(gene name synonym)|uniprotkb:HAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001165886.1|refseq:NP_004314.5|ensembl:ENSG00000107262(gene)|ensembl:ENST00000634734(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR029071|interpro:IPR036533|interpro:IPR039773|mint:Q99933|rcsb pdb:1HX1|rcsb pdb:1WXV|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|reactome:R-HSA-3371453|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|dip:DIP-3341N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:wDyAGECTy45td5tL4mnwa1txPO49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q69YZ2 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-20595042|uniprotkb:Q6P2G8|uniprotkb:Q6P2Q5|ensembl:ENSP00000428459|ensembl:ENSP00000428544 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:t200b_human(display_long)|uniprotkb:Transmembrane protein TTMA(gene name synonym)|uniprotkb:Two transmembrane domain-containing family member B(gene name synonym)|uniprotkb:TMEM200B(gene name)|psi-mi:TMEM200B(display_short)|uniprotkb:TTMB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001003682.1|refseq:NP_001165339.1|ensembl:ENSG00000253304(gene)|ensembl:ENST00000420504(transcript)|ensembl:ENST00000521452(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018787 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:nuAiZWBDNQuUiod2wJdk0o2dVEs9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q15369 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q13547 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q13435 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-749111|uniprotkb:A8K485|uniprotkb:B4DT19|uniprotkb:Q7Z627|uniprotkb:Q969K1|uniprotkb:Q96CM6|uniprotkb:Q9BWD2|intact:EBI-1052093|intact:EBI-2688256|uniprotkb:Q7L4T5|ensembl:ENSP00000318861 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:sf3b2_human(display_long)|uniprotkb:SF3B2(gene name)|psi-mi:SF3B2(display_short)|uniprotkb:SAP145(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 145 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 145(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006833.2|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006568(PSP, proline-rich)|ensembl:ENSG00000087365(gene)|ensembl:ENST00000322535(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR007180(Protein of unknown function DUF382)|rcsb pdb:2DO5|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|mint:Q13435|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Y9uCV2x4J5kqyxeO8iXjojkXocA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P62333 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P53365 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-638194|uniprotkb:D3DQT5|ensembl:ENSP00000254584|ensembl:ENSP00000379998|uniprotkb:B4E306|uniprotkb:B4DX86 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:arfp2_human(display_long)|uniprotkb:ADP-ribosylation factor-interacting protein 2(gene name synonym)|uniprotkb:Partner of RAC1(gene name synonym)|uniprotkb:ARFIP2(gene name)|psi-mi:ARFIP2(display_short)|uniprotkb:POR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001229784.1|refseq:NP_036534.1|ensembl:ENSG00000132254(gene)|ensembl:ENST00000254584(transcript)|ensembl:ENST00000396777(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|rcsb pdb:1I49|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:4DCN|reactome:R-HSA-6811440|refseq:NP_001229785.1|refseq:XP_005252897.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:q3QMUWlBIW82Szrv9jbMR6ikOZg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P35637 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P17980 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P0C0L4 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000388662|ensembl:ENSP00000396688|ensembl:ENSP00000372815 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_009224.2|refseq:NP_001002029.3|refseq:NP_001239133.1|ensembl:ENSG00000206340(gene)|ensembl:ENSG00000227746(gene)|ensembl:ENSG00000244731(gene)|ensembl:ENST00000383325(transcript)|ensembl:ENST00000421274(transcript)|ensembl:ENST00000428956(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|rcsb pdb:1HZF|rcsb pdb:4FXG|rcsb pdb:4FXK|rcsb pdb:4XAM|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01859 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1044662|uniprotkb:A6NE66|ensembl:ENSP00000374987|ensembl:ENSP00000480351 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ighg2_human(display_long)|uniprotkb:IGHG2(gene name)|psi-mi:IGHG2(display_short)|uniprotkb:Ig gamma-2 chain C region(gene name synonym)|uniprotkb:Ig gamma-2 chain C region DOT(gene name synonym)|uniprotkb:Ig gamma-2 chain C region TIL(gene name synonym)|uniprotkb:Ig gamma-2 chain C region ZIE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|rcsb pdb:4L4J|ensembl:ENSG00000211893(gene)|ensembl:ENSG00000274497(gene)|ensembl:ENST00000390545(transcript)|ensembl:ENST00000621803(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2QSC|rcsb pdb:4HAF|rcsb pdb:4HAG - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:EZkOg27Ga0FblVGpeMMQzW0s/xo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01611 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-20594998|uniprotkb:A0A0B4J2E7|ensembl:ENSP00000482464 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kvd12_human(display_long)|uniprotkb:Ig kappa chain V-I region Wes(gene name synonym)|uniprotkb:IGKV1D-12(gene name)|psi-mi:IGKV1D-12(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000278857(gene)|ensembl:ENST00000377032(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-2029482 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:sQr21ZmnYRkb2zmao+n64uIoIHA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O60812 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1046507|uniprotkb:B2RP44|ensembl:ENSP00000488130|ensembl:ENSP00000365370 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hnrc1_human(display_long)|uniprotkb:HNRPCL1(gene name synonym)|uniprotkb:HNRNPCL1(gene name)|psi-mi:HNRNPCL1(display_short)|uniprotkb:hnRNP core protein C-like 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENST00000317869(transcript)|ensembl:ENST00000634171(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:O60812|ensembl:ENSG00000179172(gene)|ensembl:ENSG00000282175(gene)|refseq:NP_001013653.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:yZcgZPlu3iuq0FR7hEQ0cvSo8K49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q86YZ3 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1047017|uniprotkb:Q5U1F4|ensembl:ENSP00000357791|uniprotkb:Q5DT20 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:horn_human(display_long)|uniprotkb:HRNR(gene name)|psi-mi:HRNR(display_short)|uniprotkb:S100A18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001009931.1|ensembl:ENSG00000197915(gene)|ensembl:ENST00000368801(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031424"(keratinization)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0043163"(cell envelope organization)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR033201|interpro:IPR034325|mint:Q86YZ3|reactome:R-HSA-6798695|ensembl:ENSP00000357791 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:j5ATFM7OQGbf5j+CZpJ3bJoadnc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q75N03 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|intact:EBI-28973894|ensembl:ENSP00000401277|uniprotkb:B7ZM03 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENST00000222597|ensembl:ENSP00000222597|ensembl:ENSP00000401277|ensembl:ENSG00000105879(gene)|ensembl:ENST00000440859(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|refseq:NP_079090.2|refseq:NP_001271220.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q5T200 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2679720|uniprotkb:Q7Z7J3|uniprotkb:Q5T1Z9|uniprotkb:O94936|uniprotkb:Q9H0L6|uniprotkb:Q8NDT6|uniprotkb:A2A323|ensembl:ENSP00000242848 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:zc3hd_human(display_long)|uniprotkb:KIAA0853(gene name synonym)|uniprotkb:ZC3H13(gene name)|psi-mi:ZC3H13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_055885.3|refseq:XP_005266369.1|ensembl:ENSG00000123200(gene)|ensembl:ENST00000242848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|mint:Q5T200|refseq:NP_001070256.1|refseq:NP_001317493.1|refseq:NP_001317494.1|refseq:NP_001317495.1|refseq:NP_001317496.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:uqLw8ZjXiweaBggvvS1ue4FvNf09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q15366 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q14865 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1210388|uniprotkb:B4DLB3|uniprotkb:Q05DG6|uniprotkb:Q32Q59|uniprotkb:Q6NZ42|uniprotkb:Q5VST4|uniprotkb:Q7Z3M4|uniprotkb:Q8N421|uniprotkb:Q9H786|ensembl:ENSP00000279873 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ari5b_human(display_long)|uniprotkb:ARID5B(gene name)|psi-mi:ARID5B(display_short)|uniprotkb:DESRT(gene name synonym)|uniprotkb:MRF2(gene name synonym)|uniprotkb:MRF1-like protein(gene name synonym)|uniprotkb:Modulator recognition factor 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_115575.1|refseq:NP_001231567.1|ensembl:ENSG00000150347(gene)|ensembl:ENST00000279873(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030325"(adrenal gland development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR030408|interpro:IPR036431|mint:Q14865|rcsb pdb:1IG6|rcsb pdb:2OEH|reactome:R-HSA-3214842|go:"GO:0005654"(nucleoplasm) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:B6FNUWNl796yE+jX/0cAknrAkuo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q02413 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1045757|intact:EBI-28968615|ensembl:ENSP00000257192|uniprotkb:B7Z845 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dsg1_human(display_long)|uniprotkb:CDHF4(gene name synonym)|uniprotkb:Desmosomal glycoprotein 1(gene name synonym)|uniprotkb:Pemphigus foliaceus antigen(gene name synonym)|uniprotkb:DSG1(gene name)|psi-mi:DSG1(display_short)|uniprotkb:Cadherin family member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSP00000257192|refseq:NP_001933.2|ensembl:ENSG00000134760(gene)|ensembl:ENST00000257192(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q02413|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:CiRFIJ9IWOol9bQpLJPxH8JArtE9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q01813 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-359022|uniprotkb:B3KS15|uniprotkb:Q5VSR7|uniprotkb:Q5VSR8|ensembl:ENSP00000370517 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:pfkap_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short)|uniprotkb:PFKF(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002618.1|ensembl:ENSG00000067057(gene)|ensembl:ENST00000381125(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q01813|rcsb pdb:4RH3|rcsb pdb:4U1R|rcsb pdb:4WL0|rcsb pdb:4XYJ|rcsb pdb:4XYK|rcsb pdb:4XZ2|reactome:R-HSA-70171|refseq:NP_001229268.1|dip:DIP-45850N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:GNmWbFrQsTMRdVphWG+3DK3wxaA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P81605 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P78395 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-348325|ensembl:ENSP00000381726|ensembl:ENSP00000381728|ensembl:ENSP00000384343|ensembl:ENSP00000385198|ensembl:ENSP00000445097|ensembl:ENSP00000445675|ensembl:ENSP00000484066|ensembl:ENSP00000486330|ensembl:ENSP00000486485|uniprotkb:O43481|uniprotkb:Q8IXN8|uniprotkb:B2R6Y7 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:prame_human(display_long)|uniprotkb:PRAME(gene name)|psi-mi:PRAME(display_short)|uniprotkb:MAPE(gene name synonym)|uniprotkb:Preferentially expressed antigen of melanoma(gene name synonym)|uniprotkb:OIP4(gene name synonym)|uniprotkb:Opa-interacting protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001278644.1|refseq:NP_001278645.1|refseq:NP_001278646.1|refseq:NP_001278648.1|ensembl:ENSG00000185686(gene)|ensembl:ENSG00000275013(gene)|interpro:IPR032675|interpro:IPR026271|ensembl:ENST00000398743(transcript)|ensembl:ENST00000402697(transcript)|ensembl:ENST00000405655(transcript)|ensembl:ENST00000539862(transcript)|ensembl:ENST00000543184(transcript)|ensembl:ENST00000617728(transcript)|ensembl:ENST00000626503(transcript)|ensembl:ENST00000628830(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|ensembl:ENST00000398741(transcript)|refseq:NP_006106.1|refseq:NP_996836.1|refseq:NP_996837.1|refseq:NP_996838.1|refseq:NP_996839.1|refseq:NP_001305056.1|refseq:NP_001305055.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:VdJSwUPADlQ09QZ6P/x7jEc3fRw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P62805 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P43686 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P43246 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P31944 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P12268 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P05783 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01602 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2371313|uniprotkb:A0A075B6S8|intact:EBI-4286966|uniprotkb:P01596|uniprotkb:P01598|uniprotkb:P01604|ensembl:ENSP00000420436|ensembl:ENSP00000488639 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kv105_human(display_long)|uniprotkb:IGKV1-5(gene name)|psi-mi:IGKV1-5(display_short)|uniprotkb:Ig kappa chain V-I region HK102(gene name synonym)|uniprotkb:Ig kappa chain V-I region CAR(gene name synonym)|uniprotkb:Ig kappa chain V-I region EU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Kue(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000243466(gene)|ensembl:ENSG00000282801(gene)|ensembl:ENST00000496168(transcript)|ensembl:ENST00000632205(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:WKovn0mvryvDbJqn6iNbiFvN+rw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01593 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-20594941|uniprotkb:P01613|uniprotkb:P80362|uniprotkb:A0A0B4J1U0|uniprotkb:P01595|uniprotkb:P01605|uniprotkb:P01607|uniprotkb:P01608|uniprotkb:P01609|ensembl:ENSP00000374800 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kvd33_human(display_long)|uniprotkb:Ig kappa chain V-I region AG(gene name synonym)|uniprotkb:Ig kappa chain V-I region Bi(gene name synonym)|uniprotkb:Ig kappa chain V-I region Lay(gene name synonym)|uniprotkb:Ig kappa chain V-I region Ni(gene name synonym)|uniprotkb:Ig kappa chain V-I region Rei(gene name synonym)|uniprotkb:Ig kappa chain V-I region Roy(gene name synonym)|uniprotkb:Ig kappa chain V-I region Scw(gene name synonym)|uniprotkb:Ig kappa chain V-I region WAT(gene name synonym)|uniprotkb:IGKV1D-33(gene name)|psi-mi:IGKV1D-33(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000239975(gene)|ensembl:ENST00000390265(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1AR2|rcsb pdb:1BWW|rcsb pdb:1REI|rcsb pdb:1WTL|rcsb pdb:4L1H|rcsb pdb:5XP1|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:+8FNYvbRPCc9GI9G4Tf+BdsBnd49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O95757 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:A6NHL2 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2954795|uniprotkb:Q9H6Z0|uniprotkb:Q4QQJ5|uniprotkb:B4DKL2|ensembl:ENSP00000369784 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tbal3_human(display_long)|uniprotkb:TUBAL3(gene name)|psi-mi:TUBAL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001165335.1|refseq:NP_079079.1|ensembl:ENSG00000178462(gene)|ensembl:ENST00000380419(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Yr8HihP2hK6YdLc8Xa9edSOOrA09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9NZL4 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356763|uniprotkb:O95351|uniprotkb:Q6ZNU5|uniprotkb:B3KQP0|uniprotkb:B4DG11|ensembl:ENSP00000255631|ensembl:ENSP00000398244|ensembl:ENSP00000467574 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hpbp1_human(display_long)|uniprotkb:HSPBP1(gene name)|psi-mi:HSPBP1(display_short)|uniprotkb:HSPBP(gene name synonym)|uniprotkb:PP1845(orf name)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym)|uniprotkb:Hsp70-binding protein 2(gene name synonym)|uniprotkb:Hsp70-interacting protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001123578.1|refseq:NP_036399.3|ensembl:ENSG00000133265(gene)|ensembl:ENST00000255631(transcript)|ensembl:ENST00000433386(transcript)|ensembl:ENST00000587922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q9NZL4|rcsb pdb:1XQR|rcsb pdb:1XQS|refseq:NP_001284529.1|refseq:XP_016882033.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:26Au2GesO5ysT/yhYX/0oOO9Md89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9C0C7 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2512975|ensembl:ENSP00000415327|ensembl:ENSP00000508322|uniprotkb:Q86XD6|uniprotkb:A6XN33|uniprotkb:Q9NXE7|uniprotkb:Q9H8Z0|intact:EBI-2556181|uniprotkb:D3DQP8|uniprotkb:G3V193 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:amra1_human(display_long)|uniprotkb:AMBRA1(gene name)|psi-mi:AMBRA1(display_short)|uniprotkb:DCAF3(gene name synonym)|uniprotkb:DDB1- and CUL4-associated factor 3(gene name synonym)|uniprotkb:KIAA1736(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000110497(gene)|ensembl:ENST00000458649(transcript)|ensembl:ENST00000683756(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|reactome:R-HSA-1632852|refseq:NP_001287660.1|refseq:NP_060219.2|refseq:NP_001254711.1|refseq:NP_001254712.1|refseq:XP_005253066.1|refseq:XP_005253068.1|refseq:XP_005253071.1|refseq:XP_006718322.1|dip:DIP-53597N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:h4yD2iL711peDzI4kttngSdTLQk9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P52701 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P49327 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P42166 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P25205 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9NSB2 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2372509|uniprotkb:B2RA43|uniprotkb:Q6ISB0|uniprotkb:Q701L6|ensembl:ENSP00000257951 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:krt84_human(display_long)|uniprotkb:KRT84(gene name)|psi-mi:KRT84(display_short)|uniprotkb:KRTHB4(gene name synonym)|uniprotkb:Type II hair keratin Hb4(gene name synonym)|uniprotkb:Keratin-84(gene name synonym)|uniprotkb:Type-II keratin Kb24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:XP_011536637.1|refseq:NP_149034.2|ensembl:ENSG00000161849(gene)|ensembl:ENST00000257951(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0035878"(nail development)|go:"GO:0045095"(keratin filament)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:j3FNHjfONdOzxrg2vXRURLaRoHI9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q92769 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q15233 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q14CN4 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1221280|uniprotkb:Q8NA87|uniprotkb:Q8WWZ0|uniprotkb:Q8WWY9|intact:EBI-11031454|uniprotkb:B4DEI8|uniprotkb:H9KV51|ensembl:ENSP00000293745|ensembl:ENSP00000441160 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k2c72_human(display_long)|uniprotkb:KRT72(gene name)|psi-mi:KRT72(display_short)|uniprotkb:Keratin-72(gene name synonym)|uniprotkb:K6IRS2(gene name synonym)|uniprotkb:KB35(gene name synonym)|uniprotkb:KRT6(gene name synonym)|uniprotkb:KRT6IRS2(gene name synonym)|uniprotkb:Cytokeratin-72(gene name synonym)|uniprotkb:Type-II keratin Kb35(gene name synonym)|uniprotkb:Type II inner root sheath-specific keratin-K6irs2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001139697.1|refseq:NP_001139698.1|refseq:NP_542785.1|ensembl:ENSG00000170486(gene)|ensembl:ENST00000293745(transcript)|ensembl:ENST00000537672(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:h6CpYy35iQ46Uka3QpurYjoGWBI9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P62191 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P52597 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P43243 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P25685 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P17844 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P15924 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|uniprotkb:D7RX09|ensembl:ENSP00000369129 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001305963.1|refseq:NP_001008844.1|refseq:NP_004406.2|go:"GO:0014704"(intercalated disc)|go:"GO:0005916"(fascia adherens)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-109N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P08670 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O00148 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9UDY4 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356960|uniprotkb:Q13431|uniprotkb:B2R824|ensembl:ENSP00000359799 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dnjb4_human(display_long)|uniprotkb:DNAJB4(gene name)|psi-mi:DNAJB4(display_short)|uniprotkb:DNAJW(gene name synonym)|uniprotkb:HLJ1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1 homolog(gene name synonym)|uniprotkb:Human liver DnaJ-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_008965.2|refseq:NP_001304028.1|refseq:NP_001304029.1|refseq:NP_001304030.1|refseq:NP_001304031.1|refseq:NP_001304032.1|ensembl:ENSG00000162616(gene)|ensembl:ENST00000370763(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UDY4 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:gN0zBtJQiTN+YYSAtMk1mddNWLU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q16531 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P62829 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P34932 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P31943 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O60506 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q13617 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P62195 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N - - crc64:29C6410C4A85A7F7 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P46379 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P02545 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O95218 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1051583|intact:EBI-1642120|intact:EBI-1163882|intact:EBI-1166395|uniprotkb:Q53GS3|uniprotkb:Q59F92|uniprotkb:Q5VV33|uniprotkb:Q8IXN6|uniprotkb:Q9UP63|uniprotkb:Q5VV34|uniprotkb:D3DQ75|ensembl:ENSP00000359958 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:zrab2_human(display_long)|uniprotkb:ZRANB2(gene name)|psi-mi:ZRANB2(display_short)|uniprotkb:ZIS(gene name synonym)|uniprotkb:ZNF265(gene name synonym)|uniprotkb:Zinc finger protein 265(gene name synonym)|uniprotkb:Zinc finger, splicing(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005446.2|refseq:NP_976225.1|ensembl:ENSG00000132485(gene)|ensembl:ENST00000370920(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR017337(Uncharacterised conserved protein UCP037956, zinc finger Ran-binding)|interpro:IPR036443|mint:O95218|rcsb pdb:1N0Z|rcsb pdb:2K1P|rcsb pdb:3G9Y - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:NSsZyRDwY5bF3I5OGvd1jGYTijY9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O15523 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2462220|uniprotkb:Q8IYV7|uniprotkb:B4DK29|uniprotkb:B4DXX7|ensembl:ENSP00000336725|ensembl:ENSP00000353284 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ddx3y_human(display_long)|uniprotkb:DDX3Y(gene name)|psi-mi:DDX3Y(display_short)|uniprotkb:DBY(gene name synonym)|uniprotkb:DEAD box protein 3, Y-chromosomal(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001116137.1|refseq:NP_004651.2|refseq:NP_001289481.1|ensembl:ENSG00000067048(gene)|ensembl:ENST00000336079(transcript)|ensembl:ENST00000360160(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007276"(gamete generation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O15523 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:dYhBr9Igq5eMq9U8g+c30nfdaKo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P31948 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006810.1|ensembl:ENSG00000168439(gene)|ensembl:ENST00000305218(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|reactome:R-HSA-3371497|reactome:R-HSA-9696273|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P26599 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-350540|ensembl:ENSP00000014112|intact:EBI-744534|uniprotkb:Q9BUQ0 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ptbp1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:PTB(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym)|uniprotkb:57 kDa RNA-binding protein PPTB-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002810.1|refseq:NP_114367.1|refseq:NP_114368.1|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0016020"(membrane)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034798|interpro:IPR035000|interpro:IPR035001|interpro:IPR035979|mint:P26599|rcsb pdb:1QM9|rcsb pdb:1SJQ|ensembl:ENSG00000011304(gene)|ensembl:ENST00000349038(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|rcsb pdb:2AD9|rcsb pdb:2ADB|rcsb pdb:2ADC|rcsb pdb:2EVZ|rcsb pdb:2N3O|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|rcsb pdb:1SJR - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:fkSnYJELgHxDP0oAQEjBmSX0HIs9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P28340 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-716569|uniprotkb:Q8NER3|uniprotkb:Q96H98|ensembl:ENSP00000406046|ensembl:ENSP00000472600|ensembl:ENSP00000473052 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dpod1_human(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase subunit delta p125(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short)|uniprotkb:POLD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002682.2|refseq:XP_011525340.1|refseq:NP_001243778.1|ensembl:ENSG00000062822(gene)|ensembl:ENST00000599857(transcript)|ensembl:ENST00000601098(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0009411"(response to UV)|ensembl:ENST00000440232(transcript)|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-5358606|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019899"(enzyme binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|mint:P28340|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-2564830|reactome:R-HSA-5358565|refseq:XP_016882370.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:bJ5Q0xOzHga/zxMOBHkuXaFXeLw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P06748 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P01857 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356114|ensembl:ENSP00000374991|ensembl:ENSP00000488387 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000211896(gene)|ensembl:ENSG00000277633(gene)|ensembl:ENST00000390549(transcript)|ensembl:ENST00000631466(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:1I7Z|rcsb pdb:3WJL|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:3WKN|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|reactome:R-HSA-166663|rcsb pdb:4XNZ|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:1YK8rrTDnOYYKW5wHI48/rYlr5o9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O43390 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q13263 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P0CG48 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-3390054|ensembl:ENSP00000344818|ensembl:ENSP00000441543|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5656121|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9613829|ensembl:ENSG00000150991(gene)|ensembl:ENST00000339647(transcript)|ensembl:ENST00000536769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:1ZO6|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|interpro:IPR000626(Ubiquitin)|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2MI8|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3PTF|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6EQI|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|refseq:NP_066289.3 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O00571 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9UL15 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P68032 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q8N163 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P68104 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9Y265 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9Y230 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q99615 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357552|ensembl:ENSP00000406463|uniprotkb:Q7Z784 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dnjc7_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)|uniprotkb:TPR2(gene name synonym)|uniprotkb:TTC2(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000168259(gene)|ensembl:ENST00000457167(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR036869|reactome:R-HSA-3371453|refseq:NP_003306.3|refseq:XP_011523469.1|refseq:XP_011523470.1|refseq:XP_011523471.1|refseq:NP_001138238.1|refseq:XP_016880483.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:eZ1/nlVA9bOU/N3yrJ3pWrnM1P09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P49411 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P10809 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q96S55 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2513471|ensembl:ENSP00000370150|ensembl:ENSP00000477551|uniprotkb:Q9NRJ6|uniprotkb:Q5W0E2|uniprotkb:Q53EP6|uniprotkb:Q8WV26|uniprotkb:Q5W0E4|uniprotkb:Q59ET8|uniprotkb:Q9H681|uniprotkb:B2RDB0 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:wrip1_human(display_long)|uniprotkb:WRNIP1(gene name)|psi-mi:WRNIP1(display_short)|uniprotkb:WHIP(gene name synonym)|uniprotkb:Werner helicase-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000124535(gene)|ensembl:ENST00000380773(transcript)|ensembl:ENST00000618555(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|interpro:IPR040539|mint:Q96S55|rcsb pdb:3VHS|rcsb pdb:3VHT|go:"GO:0017116"(single-stranded DNA helicase activity)|refseq:NP_064520.2|refseq:NP_569079.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Q8qVSqItgTO7sbWGAQ3XAoFFUr89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q00839 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P11021 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O95816 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P07355 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O95071 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P60709 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P02768 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-714423|ensembl:ENSP00000295897|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:1E78|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051087"(chaperone binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7JWN|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-879518|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|rcsb pdb:6WUW|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:1E7A|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6HSC|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|refseq:NP_000468.1|dip:DIP-29902N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P08238 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O60884 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P61978 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P08779 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356410|uniprotkb:P30654|uniprotkb:Q16402|uniprotkb:Q9UBG8|uniprotkb:A8K488|ensembl:ENSP00000301653 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k1c16_human(display_long)|uniprotkb:KRT16(gene name)|psi-mi:KRT16(display_short)|uniprotkb:KRT16A(gene name synonym)|uniprotkb:Keratin-16(gene name synonym)|uniprotkb:Cytokeratin-16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005548.2|ensembl:ENSG00000186832(gene)|ensembl:ENST00000301653(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007568"(aging)|go:"GO:0030216"(keratinocyte differentiation)|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031424"(keratinization)|go:"GO:0042633"(hair cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051546"(keratinocyte migration)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08779 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:NkPTLkWquNNlGYbrXaRkyRmKvmM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q15007 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P02533 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-702178|uniprotkb:Q14715|uniprotkb:Q53XY3|uniprotkb:Q9BUE3|uniprotkb:Q9UBN2|uniprotkb:Q9UBN3|uniprotkb:Q9UCY4|ensembl:ENSP00000167586 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k1c14_human(display_long)|uniprotkb:Cytokeratin-14(gene name synonym)|uniprotkb:KRT14(gene name)|psi-mi:KRT14(display_short)|uniprotkb:Keratin-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000517.2|dip:DIP-33874N|ensembl:ENSG00000186847(gene)|ensembl:ENST00000167586(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0008544"(epidermis development)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042633"(hair cycle)|go:"GO:0045095"(keratin filament)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990254"(keratin filament binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P02533|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:IO1k6S8FB65jQr4GNwhKuxZ1ohg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P38646 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P68366 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|ensembl:ENSP00000248437|uniprotkb:B3KNQ6|intact:EBI-11134566 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005991.1|ensembl:ENSG00000127824(gene)|ensembl:ENST00000248437(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001265481.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P04350 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P07900 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P31689 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9BQE3 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q92598 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q13885 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P68371 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q69YN4 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P02538 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-702198|uniprotkb:P48667|uniprotkb:Q08AR4|uniprotkb:Q6NT67|uniprotkb:Q96CL4|uniprotkb:A4QPC1|ensembl:ENSP00000369317 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k2c6a_human(display_long)|uniprotkb:Cytokeratin-6A(gene name synonym)|uniprotkb:Keratin-6A(gene name synonym)|uniprotkb:Cytokeratin-6D(gene name synonym)|uniprotkb:KRT6A(gene name)|psi-mi:KRT6A(display_short)|uniprotkb:K6A(gene name synonym)|uniprotkb:KRT6D(gene name synonym)|uniprotkb:Type-II keratin Kb6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005545.1|dip:DIP-533N|ensembl:ENSG00000205420(gene)|ensembl:ENST00000330722(transcript)|go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042060"(wound healing)|go:"GO:0045095"(keratin filament)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P02538|rcsb pdb:5KI0|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:feIxUFTSMnjattUda5vdGhiL9H89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P13647 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-702187|uniprotkb:Q6PI71|uniprotkb:Q6UBJ0|uniprotkb:Q8TA91|ensembl:ENSP00000252242 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k2c5_human(display_long)|uniprotkb:Cytokeratin-5(gene name synonym)|uniprotkb:58 kDa cytokeratin(gene name synonym)|uniprotkb:KRT5(gene name)|psi-mi:KRT5(display_short)|uniprotkb:Keratin-5(gene name synonym)|uniprotkb:Type-II keratin Kb5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000415.2|dip:DIP-39N|ensembl:ENSG00000186081(gene)|ensembl:ENST00000252242(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P13647|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:BdtVgSlWFYS/+zyXLNxvrcSWc4I9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q9HCE5 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P07437 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P50991 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P35527 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356382|uniprotkb:O00109|uniprotkb:Q0IJ47|uniprotkb:Q14665|ensembl:ENSP00000246662 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k1c9_human(display_long)|uniprotkb:KRT9(gene name)|psi-mi:KRT9(display_short)|uniprotkb:Keratin-9(gene name synonym)|uniprotkb:Cytokeratin-9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000217.2|ensembl:ENSG00000171403(gene)|ensembl:ENST00000246662(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0043588"(skin development)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P35527|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:m4EXfxbK2t1/EmI04YODKTJ02Zw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P13645 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-465144|ensembl:ENSP00000269576|uniprotkb:Q14664|uniprotkb:Q8N175 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k1c10_human(display_long)|uniprotkb:KRT10(gene name)|psi-mi:KRT10(display_short)|uniprotkb:Cytokeratin-10(gene name synonym)|uniprotkb:KPP(gene name synonym)|uniprotkb:Keratin-10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000186395(gene)|ensembl:ENST00000269576(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P13645|rcsb pdb:3ASW|rcsb pdb:4F1Z|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6EC0|rcsb pdb:6UUI|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000412.3 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:z100yyq3b63P0ARy2lE2ELyJeik9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 intact:EBI-11820565 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 - psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:1304"(molecule set) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N - - - comment:P0DMV8,P0DMV9 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 - - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P08107 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P48643 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P35908 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-1247312|uniprotkb:Q4VAQ2|ensembl:ENSP00000310861 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k22e_human(display_long)|uniprotkb:KRT2(gene name)|psi-mi:KRT2(display_short)|uniprotkb:KRT2A(gene name synonym)|uniprotkb:KRT2E(gene name synonym)|uniprotkb:Cytokeratin-2e(gene name synonym)|uniprotkb:Keratin-2e(gene name synonym)|uniprotkb:Type-II keratin Kb2(gene name synonym)|uniprotkb:Keratin-2 epidermis(gene name synonym)|uniprotkb:Epithelial keratin-2e(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_000414.2|ensembl:ENSG00000172867(gene)|ensembl:ENST00000309680(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003334"(keratinocyte development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|go:"GO:0032980"(keratinocyte activation)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045095"(keratin filament)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P35908|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0051546"(keratinocyte migration) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:T7LeB8nkZzNjUb8DWdkxbrl5f789606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P40227 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P17987 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P50990 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P49368 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P04264 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-298429|uniprotkb:Q14720|uniprotkb:Q6GSJ0|uniprotkb:B2RA01|uniprotkb:Q9H298|ensembl:ENSP00000252244|uniprotkb:P85925|uniprotkb:P86104 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:k2c1_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:KRTA(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Cytokeratin-1(gene name synonym)|uniprotkb:67 kDa cytokeratin(gene name synonym)|uniprotkb:Hair alpha protein(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006112.3|ensembl:ENSG00000167768(gene)|ensembl:ENST00000252244(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045095"(keratin filament)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR032449|interpro:IPR039008|mint:P04264|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6UUI|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:TeAC3i2hWTS2lgXT0i4agp9nv349606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q99832 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P11142 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:P78371 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:O95259 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2909270|ensembl:ENSP00000271751|uniprotkb:B1AQ26|uniprotkb:O76035|uniprotkb:Q14CL3 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:kcnh1_human(display_long)|uniprotkb:KCNH1(gene name)|psi-mi:KCNH1(display_short)|uniprotkb:EAG(gene name synonym)|uniprotkb:EAG1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv10.1(gene name synonym)|uniprotkb:Ether-a-go-go potassium channel 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20594935|imex:IM-26525-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N go:"GO:0030673"(axolemma)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003949(Potassium channel, voltage-dependent, EAG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR030170|interpro:IPR035965|rcsb pdb:5J7E|reactome:R-HSA-1296072|ensembl:ENSG00000143473(gene)|ensembl:ENST00000271751(transcript)|go:"GO:0001964"(startle response)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|refseq:NP_002229.1|refseq:NP_758872.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:jDc4JwcX74sosVPIU9k9weg8n3A9606 - false flag tag:n-n|his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P53999 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-998260|uniprotkb:Q96L29|ensembl:ENSP00000265073|ensembl:ENSP00000422078|ensembl:ENSP00000422806|ensembl:ENSP00000426850|ensembl:ENSP00000427100 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tcp4_human(display_long)|uniprotkb:SUB1 homolog(gene name synonym)|uniprotkb:Positive cofactor 4(gene name synonym)|uniprotkb:p14(gene name synonym)|uniprotkb:SUB1(gene name)|psi-mi:SUB1(display_short)|uniprotkb:PC4(gene name synonym)|uniprotkb:RPO2TC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:XP_011512246.1|ensembl:ENSG00000113387(gene)|ensembl:ENST00000265073(transcript)|ensembl:ENST00000502897(transcript)|ensembl:ENST00000506237(transcript)|ensembl:ENST00000512913(transcript)|ensembl:ENST00000515355(transcript)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003173(Transcriptional coactivator p15)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|mint:P53999|rcsb pdb:1PCF|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|rcsb pdb:2C62|rcsb pdb:2PHE|rcsb pdb:4USG|go:"GO:0003697"(single-stranded DNA binding)|rcsb pdb:6YCS|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0051053"(negative regulation of DNA metabolic process)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|refseq:NP_006704.3|refseq:XP_016864475.1|refseq:XP_016864476.1|dip:DIP-29044N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:FqBKBuLmQS+idbd68EdKsTCzPg89606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q68DL7 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-11323181|uniprotkb:A6NME8|ensembl:ENSP00000464330 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:cr063_human(display_long)|uniprotkb:C18orf63(gene name)|psi-mi:C18orf63(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001167594.1|ensembl:ENSG00000206043(gene)|ensembl:ENST00000579455(transcript)|interpro:IPR031643 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:PJOEDQ5xaJ+48HJclZUnMLlpabA9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P01593 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-20594941|uniprotkb:P01613|uniprotkb:P80362|uniprotkb:A0A0B4J1U0|uniprotkb:P01595|uniprotkb:P01605|uniprotkb:P01607|uniprotkb:P01608|uniprotkb:P01609|ensembl:ENSP00000374800 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:kvd33_human(display_long)|uniprotkb:Ig kappa chain V-I region AG(gene name synonym)|uniprotkb:Ig kappa chain V-I region Bi(gene name synonym)|uniprotkb:Ig kappa chain V-I region Lay(gene name synonym)|uniprotkb:Ig kappa chain V-I region Ni(gene name synonym)|uniprotkb:Ig kappa chain V-I region Rei(gene name synonym)|uniprotkb:Ig kappa chain V-I region Roy(gene name synonym)|uniprotkb:Ig kappa chain V-I region Scw(gene name synonym)|uniprotkb:Ig kappa chain V-I region WAT(gene name synonym)|uniprotkb:IGKV1D-33(gene name)|psi-mi:IGKV1D-33(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000239975(gene)|ensembl:ENST00000390265(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1AR2|rcsb pdb:1BWW|rcsb pdb:1REI|rcsb pdb:1WTL|rcsb pdb:4L1H|rcsb pdb:5XP1|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:+8FNYvbRPCc9GI9G4Tf+BdsBnd49606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P01602 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2371313|uniprotkb:A0A075B6S8|intact:EBI-4286966|uniprotkb:P01596|uniprotkb:P01598|uniprotkb:P01604|ensembl:ENSP00000420436|ensembl:ENSP00000488639 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:kv105_human(display_long)|uniprotkb:IGKV1-5(gene name)|psi-mi:IGKV1-5(display_short)|uniprotkb:Ig kappa chain V-I region HK102(gene name synonym)|uniprotkb:Ig kappa chain V-I region CAR(gene name synonym)|uniprotkb:Ig kappa chain V-I region EU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Kue(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000243466(gene)|ensembl:ENSG00000282801(gene)|ensembl:ENST00000496168(transcript)|ensembl:ENST00000632205(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:WKovn0mvryvDbJqn6iNbiFvN+rw9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q9NSB4 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1045341|ensembl:ENSP00000257974 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:krt82_human(display_long)|uniprotkb:Type II hair keratin Hb2(gene name synonym)|uniprotkb:Keratin-82(gene name synonym)|uniprotkb:KRT82(gene name)|psi-mi:KRT82(display_short)|uniprotkb:KRTHB2(gene name synonym)|uniprotkb:Type-II keratin Kb22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_149022.3|ensembl:ENSG00000161850(gene)|ensembl:ENST00000257974(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045095"(keratin filament)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:FME7rP4Rs4fHO5xDfPCq6IRc3IA9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q99943 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-3893468|uniprotkb:A2BFI5|uniprotkb:Q5BL03|ensembl:ENSP00000337463|ensembl:ENSP00000364245|ensembl:ENSP00000364248|ensembl:ENSP00000372782|ensembl:ENSP00000378874|ensembl:ENSP00000378875|ensembl:ENSP00000378877|ensembl:ENSP00000382721|ensembl:ENSP00000382723|ensembl:ENSP00000382725|ensembl:ENSP00000382726|ensembl:ENSP00000382728|ensembl:ENSP00000387810|ensembl:ENSP00000388090|ensembl:ENSP00000388253|ensembl:ENSP00000388815|ensembl:ENSP00000388870|ensembl:ENSP00000389516|ensembl:ENSP00000390988|ensembl:ENSP00000392083|ensembl:ENSP00000392820|ensembl:ENSP00000394919|ensembl:ENSP00000395613|ensembl:ENSP00000395863|ensembl:ENSP00000397765|ensembl:ENSP00000398016|ensembl:ENSP00000401287|ensembl:ENSP00000401410|ensembl:ENSP00000404106|ensembl:ENSP00000405565|ensembl:ENSP00000405864|ensembl:ENSP00000406582|ensembl:ENSP00000406614|ensembl:ENSP00000406615|ensembl:ENSP00000387738|ensembl:ENSP00000408032|ensembl:ENSP00000408842|ensembl:ENSP00000410831|ensembl:ENSP00000412304|ensembl:ENSP00000412805|ensembl:ENSP00000415015|ensembl:ENSP00000407189 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:plca_human(display_long)|uniprotkb:AGPAT1(gene name)|psi-mi:AGPAT1(display_short)|uniprotkb:G15(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 1(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase alpha(gene name synonym)|uniprotkb:Protein G15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:XP_011512536.1|refseq:NP_006402.1|refseq:NP_116130.2|refseq:XP_005248863.1|ensembl:ENSG00000204310(gene)|ensembl:ENSG00000206324(gene)|ensembl:ENSG00000226467(gene)|ensembl:ENSG00000227642(gene)|ensembl:ENSG00000228892(gene)|ensembl:ENSG00000235758(gene)|ensembl:ENSG00000236873(gene)|ensembl:ENST00000336984(transcript)|ensembl:ENST00000375104(transcript)|ensembl:ENST00000375107(transcript)|ensembl:ENST00000383294(transcript)|ensembl:ENST00000395496(transcript)|ensembl:ENST00000395497(transcript)|ensembl:ENST00000395499(transcript)|ensembl:ENST00000399825(transcript)|ensembl:ENST00000399827(transcript)|ensembl:ENST00000399829(transcript)|ensembl:ENST00000399830(transcript)|ensembl:ENST00000399833(transcript)|ensembl:ENST00000414520(transcript)|ensembl:ENST00000414933(transcript)|ensembl:ENST00000416363(transcript)|ensembl:ENST00000417388(transcript)|ensembl:ENST00000424030(transcript)|ensembl:ENST00000425204(transcript)|ensembl:ENST00000425572(transcript)|ensembl:ENST00000427763(transcript)|ensembl:ENST00000430226(transcript)|ensembl:ENST00000430777(transcript)|ensembl:ENST00000433376(transcript)|ensembl:ENST00000433896(transcript)|ensembl:ENST00000434614(transcript)|ensembl:ENST00000436149(transcript)|ensembl:ENST00000439774(transcript)|ensembl:ENST00000440840(transcript)|ensembl:ENST00000444369(transcript)|ensembl:ENST00000446323(transcript)|ensembl:ENST00000446463(transcript)|ensembl:ENST00000448196(transcript)|ensembl:ENST00000449776(transcript)|ensembl:ENST00000451833(transcript)|ensembl:ENST00000452393(transcript)|ensembl:ENST00000452427(transcript)|ensembl:ENST00000454929(transcript)|ensembl:ENST00000455898(transcript)|ensembl:ENST00000456421(transcript)|ensembl:ENST00000456679(transcript)|ensembl:ENST00000457923(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-HSA-1483166|reactome:R-HSA-163765|ensembl:ENST00000415173(transcript) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:79aLEXZSVTqCLBYxPUnUPT5n0ME9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P32119 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q9Y4Z0 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-372521|ensembl:ENSP00000469468 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:lsm4_human(display_long)|uniprotkb:Glycine-rich protein(gene name synonym)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_036453.1|ensembl:ENSG00000130520(gene)|ensembl:ENST00000593829(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033962"(P-body assembly)|go:"GO:0042731"(PH domain binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0043005"(neuron projection)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|dip:DIP-31209N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:FlaQveuBbixGvfX47pCm26xscT09606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q9ULV4 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-351384|uniprotkb:Q9NSK5|uniprotkb:B3KU12|ensembl:ENSP00000261401|ensembl:ENSP00000438341|intact:EBI-4404698|uniprotkb:A7MAP0|uniprotkb:A7MAP1 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:cor1c_human(display_long)|uniprotkb:CORO1C(gene name)|psi-mi:CORO1C(display_short)|uniprotkb:CRNN4(gene name synonym)|uniprotkb:Coronin-3(gene name synonym)|uniprotkb:hCRNN4(gene name synonym)|uniprotkb:CRN2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001263400.1|refseq:NP_055140.1|ensembl:ENSG00000110880(gene)|ensembl:ENST00000261401(transcript)|ensembl:ENST00000541050(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0090148"(membrane fission)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0016197"(endosomal transport)|go:"GO:0097750"(endosome membrane tubulation)|go:"GO:0140285"(endosome fission)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027333|interpro:IPR036322|mint:Q9ULV4|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|refseq:NP_001098707.1|refseq:XP_016874610.1|refseq:XP_016874611.1|refseq:XP_016874612.1|dip:DIP-33138N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:Em/LQxjBk9n4tobk5ksyDfFSyeU9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q9UBS4 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q9HCU9 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-714781|uniprotkb:Q6IAI2|ensembl:ENSP00000353042 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:brms1_human(display_long)|uniprotkb:BRMS1(gene name)|psi-mi:BRMS1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000174744(gene)|ensembl:ENST00000359957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR013907(Sds3-like)|rcsb pdb:2XUS|rcsb pdb:4AUV|reactome:R-HSA-3214815|reactome:R-HSA-9679191|refseq:NP_056214.1|dip:DIP-24250N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:kuaR4dVP6xzSOMHwSd+CDrLU/uo9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q9GZT3 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1050793|uniprotkb:J3KMY7|ensembl:ENSP00000450909|intact:EBI-10967524 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:slirp_human(display_long)|uniprotkb:SLIRP(gene name)|psi-mi:SLIRP(display_short)|uniprotkb:C14orf156(gene name synonym)|uniprotkb:DC23(orf name)|uniprotkb:DC50(orf name)|uniprotkb:PD04872(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_112487.1|refseq:NP_001254792.1|refseq:NP_001254793.1|ensembl:ENSG00000119705(gene)|ensembl:ENST00000557342(transcript)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0036126"(sperm flagellum)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034152|interpro:IPR035979|mint:Q9GZT3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:8sPWOtmxPTOVlthXwBiIIp/+6go9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q9BQD3 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-739657|uniprotkb:O76098|ensembl:ENSP00000472678|ensembl:ENSP00000472836|ensembl:ENSP00000222307|ensembl:ENSP00000438903|ensembl:ENSP00000443549|ensembl:ENSP00000468990|ensembl:ENSP00000471554 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:kxdl1_human(display_long)|uniprotkb:KXD1(gene name)|psi-mi:KXD1(display_short)|uniprotkb:C19orf50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001165419.1|refseq:NP_001165420.1|refseq:NP_076974.2|ensembl:ENST00000222307(transcript)|ensembl:ENST00000539106(transcript)|ensembl:ENST00000540691(transcript)|ensembl:ENST00000595073(transcript)|ensembl:ENST00000599319(transcript)|ensembl:ENST00000600654(transcript)|ensembl:ENST00000602094(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|ensembl:ENSG00000105700(gene)|refseq:XP_016882770.1|refseq:XP_011526574.1|refseq:XP_011526575.1|refseq:XP_006722946.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:5BoR6AN0Ywb1eI04Rw4chmlWVI09606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q99962 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q99714 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q92521 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-20595402|uniprotkb:Q53FF9|uniprotkb:Q8WVN7|ensembl:ENSP00000164305 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:pigb_human(display_long)|uniprotkb:GPI mannosyltransferase III(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class B protein(gene name synonym)|uniprotkb:PIGB(gene name)|psi-mi:PIGB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_004846.4|go:"GO:0004376"(glycolipid mannosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0097502"(mannosylation)|interpro:IPR005599(Alg9-like mannosyltransferase)|interpro:IPR039521|reactome:R-HSA-162710|ensembl:ENSG00000069943(gene)|ensembl:ENST00000164305(transcript)|go:"GO:0000026"(alpha-1,2-mannosyltransferase activity)|go:"GO:0000030"(mannosyltransferase activity) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:mPO1zjTksU2nXnYLmABQMRqAnvA9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q8N1N4 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1056564|uniprotkb:Q7RTT2|uniprotkb:Q5HYM7|uniprotkb:A8K4D6|ensembl:ENSP00000306261 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k2c78_human(display_long)|uniprotkb:KRT78(gene name)|psi-mi:KRT78(display_short)|uniprotkb:K5B(gene name synonym)|uniprotkb:KB40(gene name synonym)|uniprotkb:Cytokeratin-78(gene name synonym)|uniprotkb:Type-II keratin Kb40(gene name synonym)|uniprotkb:Keratin-5b(gene name synonym)|uniprotkb:Keratin-78(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001287743.1|refseq:NP_775487.2|ensembl:ENSG00000170423(gene)|ensembl:ENST00000304620(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:7DFQlPKPQ4Bu1Q5+nxLQufA7ghU9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q86XI8 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2682158|ensembl:ENSP00000331363|uniprotkb:A0A087WWL5 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:zswm9_human(display_long)|uniprotkb:ZSWIM9(gene name)|psi-mi:ZSWIM9(display_short)|uniprotkb:C19orf68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_955373.3|ensembl:ENSG00000185453(gene)|ensembl:ENST00000328759(transcript)|interpro:IPR040854|mint:Q86XI8|refseq:XP_006723268.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:4wOy3iLGFg7lgvbA8nWPUgIgS0w9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q6ZVX7 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2877737|ensembl:ENSP00000342137|uniprotkb:Q6NVV5 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:fbx50_human(display_long)|uniprotkb:NCCRP1(gene name)|psi-mi:NCCRP1(display_short)|uniprotkb:FBXO50(gene name synonym)|uniprotkb:NCC receptor protein 1 homolog(gene name synonym)|uniprotkb:Non-specific cytotoxic cell receptor protein 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000188505(gene)|ensembl:ENST00000339852(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR039752|refseq:NP_001001414.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:Gj02wJIGGIYTIMxQmqn5rIePVLQ9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q6NXT2 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2868501|uniprotkb:E9P281|ensembl:ENSP00000339835 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:h3c_human(display_long)|uniprotkb:H3-5(gene name)|psi-mi:H3-5(display_short)|uniprotkb:H3F3C(gene name synonym)|uniprotkb:Histone H3.5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001013721.2|go:"GO:0006997"(nucleus organization)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0007566"(embryo implantation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:1902340"(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q6NXT2|rcsb pdb:2PUY|rcsb pdb:3KV4|rcsb pdb:4Z5T|rcsb pdb:5BWN|rcsb pdb:5BWO|rcsb pdb:5F6K|rcsb pdb:5I3L|rcsb pdb:6OI3|ensembl:ENSG00000188375(gene)|ensembl:ENST00000340398(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001740"(Barr body)|go:"GO:0005634"(nucleus) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:d8jgPwPl7fXRRpWh+ON9tiyrgnY9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q5T750 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2563033|ensembl:ENSP00000357764|uniprotkb:O14634 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:xp32_human(display_long)|uniprotkb:XP32(gene name)|psi-mi:XP32(display_short)|uniprotkb:C1orf68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001019850.1|ensembl:ENSG00000198854(gene)|ensembl:ENST00000368775(transcript)|go:"GO:0008544"(epidermis development)|interpro:IPR026078|mint:Q5T750 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:QHKngjyz/pqUrpu1XJ8NINDtmm49606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q5K651 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2814750|uniprotkb:Q9NXS8|uniprotkb:Q5K649|uniprotkb:Q6P080|uniprotkb:A2RU68|uniprotkb:Q8IVG6|uniprotkb:Q75N21|ensembl:ENSP00000369292|ensembl:ENSP00000484636 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:samd9_human(display_long)|uniprotkb:SAMD9(gene name)|psi-mi:SAMD9(display_short)|uniprotkb:C7orf5(gene name synonym)|uniprotkb:DRIF1(gene name synonym)|uniprotkb:KIAA2004(gene name synonym)|uniprotkb:OEF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001180236.1|refseq:NP_060124.2|ensembl:ENSG00000205413(gene)|ensembl:ENST00000379958(transcript)|ensembl:ENST00000620985(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR027417 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:dMlEv0BW7qhY0m4QQZqxSSU7BSU9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q5D862 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2952722|ensembl:ENSP00000373370|uniprotkb:Q9H4U1 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:fila2_human(display_long)|uniprotkb:FLG2(gene name)|psi-mi:FLG2(display_short)|uniprotkb:IFPS(gene name synonym)|uniprotkb:Intermediate filament-associated and psoriasis-susceptibility protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSP00000373370|ensembl:ENSG00000143520(gene)|ensembl:ENST00000388718(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003303(Filaggrin)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR034325|mint:Q5D862|reactome:R-HSA-6798695|go:"GO:0036457"(keratohyalin granule)|refseq:NP_001014364.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:b0VRX4uLQtUVeodRvtwEWgfmzZc9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q15366 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q13867 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q05707 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2528599|uniprotkb:B2RU07|uniprotkb:O00260|uniprotkb:O00261|uniprotkb:O00262|uniprotkb:Q05708|uniprotkb:Q5XJ18|uniprotkb:Q96C67|uniprotkb:Q9UDF6|ensembl:ENSP00000297848 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:coea1_human(display_long)|uniprotkb:COL14A1(gene name)|psi-mi:COL14A1(display_short)|uniprotkb:UND(gene name synonym)|uniprotkb:Undulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:XP_016869298.1|refseq:NP_066933.1|refseq:XP_005251116.1|refseq:XP_006716714.1|ensembl:ENSG00000187955(gene)|ensembl:ENST00000297848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005596"(collagen type XIV trimer)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001791(Laminin G)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036465|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8948216 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:8eQ55YOi3IK4OWPI57s3ak2q4bg9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q00839 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P80748 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-20595355|uniprotkb:A0A075B6J7|uniprotkb:P01719|uniprotkb:P01720|ensembl:ENSP00000374843 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:lv321_human(display_long)|uniprotkb:Ig lambda chain V-III region LOI(gene name synonym)|uniprotkb:Ig lambda chain V-V region DEL(gene name synonym)|uniprotkb:Ig lambda chain V-VII region MOT(gene name synonym)|uniprotkb:IGLV3-21(gene name)|psi-mi:IGLV3-21(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000211662(gene)|ensembl:ENST00000390308(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2LOI|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:HXoRjP12EeTO//xTM5m89JvkceQ9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P63167 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P49411 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P47755 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-762451|uniprotkb:B4DG50|ensembl:ENSP00000354947 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_006127.1|ensembl:ENSG00000198898(gene)|ensembl:ENST00000361183(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|go:"GO:0016020"(membrane) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P43246 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P37108 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-353399|uniprotkb:Q6B0K5|intact:EBI-1053250|uniprotkb:Q96Q14|uniprotkb:B5BUF5|ensembl:ENSP00000267884 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:srp14_human(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:18 kDa Alu RNA-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_003125.3|dip:DIP-6152N|ensembl:ENSG00000140319(gene)|ensembl:ENST00000267884(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045047"(protein targeting to ER)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|mint:P37108|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYJ|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-6798695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:0xHelIgJbXaUrFsHGoj1wDQKdPs9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P35030 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P31944 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P15531 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P10599 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|uniprotkb:Q9UDG5|intact:EBI-1042712|ensembl:ENSP00000363641 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|ensembl:ENSG00000136810(gene)|ensembl:ENST00000374517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:1W1C|rcsb pdb:1W1E|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P0C0S5 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1199859|uniprotkb:P17317|uniprotkb:Q6I9U0|uniprotkb:B2RD56|ensembl:ENSP00000296417 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:h2az_human(display_long)|uniprotkb:H2AZ1(gene name)|psi-mi:H2AZ1(display_short)|uniprotkb:H2AFZ(gene name synonym)|uniprotkb:H2AZ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_002097.1|ensembl:ENSG00000164032(gene)|ensembl:ENST00000296417(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S5|rcsb pdb:1F66|rcsb pdb:3WA9|rcsb pdb:4CAY|rcsb pdb:4NFT|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5CHL|rcsb pdb:5FUG|rcsb pdb:5Z30|rcsb pdb:6JOU|rcsb pdb:6KO2|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-38593N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:0FrzM1TXlduSQ0NNVl0C9uqCUGI9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P0C0L4 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000388662|ensembl:ENSP00000396688|ensembl:ENSP00000372815 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_009224.2|refseq:NP_001002029.3|refseq:NP_001239133.1|ensembl:ENSG00000206340(gene)|ensembl:ENSG00000227746(gene)|ensembl:ENSG00000244731(gene)|ensembl:ENST00000383325(transcript)|ensembl:ENST00000421274(transcript)|ensembl:ENST00000428956(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|rcsb pdb:1HZF|rcsb pdb:4FXG|rcsb pdb:4FXK|rcsb pdb:4XAM|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P08670 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P08579 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1053651|uniprotkb:Q9UJD4|uniprotkb:B2R7J3|uniprotkb:D3DW21|ensembl:ENSP00000246071|ensembl:ENSP00000367178 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:ru2b_human(display_long)|uniprotkb:SNRPB2(gene name)|psi-mi:SNRPB2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_003083.1|refseq:NP_937863.1|ensembl:ENSG00000125870(gene)|ensembl:ENST00000246071(transcript)|ensembl:ENST00000377943(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070990"(snRNP binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034562|interpro:IPR034564|interpro:IPR035979|mint:P08579|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:AzDL3wfFG4HmOfTs8NJL6bWjgrc9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P07477 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P04083 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:QKmqz+UsAof35B/so2qKLQjn2v09606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P01594 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-15853604|ensembl:ENSP00000420020|ensembl:ENSP00000487732|uniprotkb:A0A087WZH9|uniprotkb:P01603 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:kv133_human(display_long)|uniprotkb:IGKV1-33(gene name)|psi-mi:IGKV1-33(display_short)|uniprotkb:Ig kappa chain V-I region AU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Ka(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000242076(gene)|ensembl:ENSG00000282811(gene)|ensembl:ENST00000473726(transcript)|ensembl:ENST00000632835(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B0W|rcsb pdb:1JV5|rcsb pdb:1QP1|rcsb pdb:2Q20|rcsb pdb:3CDC|rcsb pdb:3CDF|rcsb pdb:3CDY|rcsb pdb:4K07|rcsb pdb:7CZQ|rcsb pdb:7CZU|rcsb pdb:7CZV|reactome:R-HSA-166663|reactome:R-HSA-173623|go:"GO:0005615"(extracellular space)|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|dip:DIP-58572N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:+8FNYvbRPCc9GI9G4Tf+BdsBnd49606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P01593 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-20594941|uniprotkb:P01613|uniprotkb:P80362|uniprotkb:A0A0B4J1U0|uniprotkb:P01595|uniprotkb:P01605|uniprotkb:P01607|uniprotkb:P01608|uniprotkb:P01609|ensembl:ENSP00000374800 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:kvd33_human(display_long)|uniprotkb:Ig kappa chain V-I region AG(gene name synonym)|uniprotkb:Ig kappa chain V-I region Bi(gene name synonym)|uniprotkb:Ig kappa chain V-I region Lay(gene name synonym)|uniprotkb:Ig kappa chain V-I region Ni(gene name synonym)|uniprotkb:Ig kappa chain V-I region Rei(gene name synonym)|uniprotkb:Ig kappa chain V-I region Roy(gene name synonym)|uniprotkb:Ig kappa chain V-I region Scw(gene name synonym)|uniprotkb:Ig kappa chain V-I region WAT(gene name synonym)|uniprotkb:IGKV1D-33(gene name)|psi-mi:IGKV1D-33(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000239975(gene)|ensembl:ENST00000390265(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1AR2|rcsb pdb:1BWW|rcsb pdb:1REI|rcsb pdb:1WTL|rcsb pdb:4L1H|rcsb pdb:5XP1|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:+8FNYvbRPCc9GI9G4Tf+BdsBnd49606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P01040 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:O75865 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-743573|uniprotkb:Q9BQ45|uniprotkb:Q9P092|uniprotkb:K7ERB1|uniprotkb:K7ERQ4|ensembl:ENSP00000468612 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tpc6a_human(display_long)|uniprotkb:TRAPPC6A(gene name)|psi-mi:TRAPPC6A(display_short)|uniprotkb:HSPC289(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_077013.1|refseq:NP_001257821.1|refseq:NP_001257822.1|refseq:NP_001257820.1|ensembl:ENSG00000007255(gene)|ensembl:ENST00000585934(transcript)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR037992|mint:O75865|rcsb pdb:2C0J|rcsb pdb:2J3T|reactome:R-HSA-204005|reactome:R-HSA-8876198|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:1903232"(melanosome assembly)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|dip:DIP-37869N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:fj7bq0NxA91fevb0Iu/0+Hx05Tk9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:O60812 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1046507|uniprotkb:B2RP44|ensembl:ENSP00000488130|ensembl:ENSP00000365370 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hnrc1_human(display_long)|uniprotkb:HNRPCL1(gene name synonym)|uniprotkb:HNRNPCL1(gene name)|psi-mi:HNRNPCL1(display_short)|uniprotkb:hnRNP core protein C-like 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENST00000317869(transcript)|ensembl:ENST00000634171(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:O60812|ensembl:ENSG00000179172(gene)|ensembl:ENSG00000282175(gene)|refseq:NP_001013653.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:yZcgZPlu3iuq0FR7hEQ0cvSo8K49606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:O00148 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P48741 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-877656|uniprotkb:P19790 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hsp77_human(display_long)|uniprotkb:Heat shock 70 kDa protein B(gene name synonym)|uniprotkb:HSPA7(gene name)|psi-mi:HSPA7(display_short)|uniprotkb:HSP70B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|reactome:R-HSA-3371453|interpro:IPR043129 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:ZXOhfWYdKdW1ek+VsKZyF/Zo84o9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q9BQE3 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q96GS4 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-10193358|uniprotkb:Q9NXW8|uniprotkb:Q53HS4|ensembl:ENSP00000373669 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:borc6_human(display_long)|uniprotkb:BORCS6(gene name)|psi-mi:BORCS6(display_short)|uniprotkb:C17orf59(gene name synonym)|uniprotkb:Lysosome-dispersing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_060092.2|ensembl:ENSG00000196544(gene)|ensembl:ENST00000389017(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0099078"(BORC complex)|interpro:IPR019314|dip:DIP-29465N - - crc64:BBA89770528FA9E9 figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:ZAfDrF1Nb8RnQqg0T50TaEJ3Xp09606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q6NSZ9 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-9995630|uniprotkb:A4D290|uniprotkb:D6W5T5|uniprotkb:Q14C82|uniprotkb:Q14C99|uniprotkb:Q5EBM9|uniprotkb:Q6DJZ0|uniprotkb:Q6N032|uniprotkb:Q6ZML3|ensembl:ENSP00000334800|ensembl:ENSP00000377708 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:zsc25_human(display_long)|uniprotkb:ZSCAN25(gene name)|psi-mi:ZSCAN25(display_short)|uniprotkb:ZNF498(gene name synonym)|uniprotkb:Zinc finger protein 498(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_660090.2|refseq:XP_005250251.1|refseq:XP_016867313.1|refseq:XP_011514207.1|refseq:XP_011514208.1|refseq:XP_011514209.1|ensembl:ENSG00000197037(gene)|ensembl:ENST00000334715(transcript)|ensembl:ENST00000394152(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_011514210.1|refseq:XP_016867314.1|refseq:XP_016867315.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:oMQQw4jg3xovE7lw8kMxWCDzF109606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P81605 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P31943 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P22234 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P17844 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P02751 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P01602 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2371313|uniprotkb:A0A075B6S8|intact:EBI-4286966|uniprotkb:P01596|uniprotkb:P01598|uniprotkb:P01604|ensembl:ENSP00000420436|ensembl:ENSP00000488639 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:kv105_human(display_long)|uniprotkb:IGKV1-5(gene name)|psi-mi:IGKV1-5(display_short)|uniprotkb:Ig kappa chain V-I region HK102(gene name synonym)|uniprotkb:Ig kappa chain V-I region CAR(gene name synonym)|uniprotkb:Ig kappa chain V-I region EU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Kue(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000243466(gene)|ensembl:ENSG00000282801(gene)|ensembl:ENST00000496168(transcript)|ensembl:ENST00000632205(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:WKovn0mvryvDbJqn6iNbiFvN+rw9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:O60814 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q14532 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1044146|ensembl:ENSP00000225899 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k1h2_human(display_long)|uniprotkb:KRT32(gene name)|psi-mi:KRT32(display_short)|uniprotkb:HHA2(gene name synonym)|uniprotkb:HKA2(gene name synonym)|uniprotkb:Hair keratin, type I Ha2(gene name synonym)|uniprotkb:Keratin-32(gene name synonym)|uniprotkb:KRTHA2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000108759(gene)|ensembl:ENST00000225899(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002269.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:fbPhQU7W0HKcorCfIL28y6rckrc9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P62805 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q96T37 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2514922|ensembl:ENSP00000358799|ensembl:ENSP00000483133|uniprotkb:Q96SC9|uniprotkb:Q5D058|uniprotkb:Q96SD0|uniprotkb:Q5T613|uniprotkb:Q96SC5|uniprotkb:Q96T38|uniprotkb:Q9BRA5|uniprotkb:Q96SC6|uniprotkb:Q9H9Y0|uniprotkb:Q96PE4|uniprotkb:Q9H6R8|uniprotkb:Q4V760|uniprotkb:A1A693|uniprotkb:Q3ZB86|uniprotkb:Q86VW9 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:rbm15_human(display_long)|uniprotkb:RBM15(gene name)|psi-mi:RBM15(display_short)|uniprotkb:OTT(gene name synonym)|uniprotkb:OTT1(gene name synonym)|uniprotkb:RNA-binding motif protein 15(gene name synonym)|uniprotkb:One-twenty two protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000162775(gene)|ensembl:ENST00000369784(transcript)|ensembl:ENST00000618772(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0038163"(thrombopoietin-mediated signaling pathway)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0048536"(spleen development)|go:"GO:0060674"(placenta blood vessel development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034470|interpro:IPR034472|interpro:IPR034473|interpro:IPR035979|mint:Q96T37|go:"GO:0060412"(ventricular septum morphogenesis)|refseq:NP_001188474.1|refseq:NP_073605.4|ensembl:ENSP00000358799|ensembl:ENST00000487146|ensembl:ENSP00000473552|ensembl:ENST00000602849|ensembl:ENSP00000473638|ensembl:ENSP00000483133|ensembl:ENST00000652342|ensembl:ENSP00000498328|ensembl:ENST00000652747|ensembl:ENSP00000498634 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:t7EkMQbmDxPl/X8yPkBi1zCywac9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q96EK4 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q06830 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P07437 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P01611 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-20594998|uniprotkb:A0A0B4J2E7|ensembl:ENSP00000482464 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:kvd12_human(display_long)|uniprotkb:Ig kappa chain V-I region Wes(gene name synonym)|uniprotkb:IGKV1D-12(gene name)|psi-mi:IGKV1D-12(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000278857(gene)|ensembl:ENST00000377032(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-2029482 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:sQr21ZmnYRkb2zmao+n64uIoIHA9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q86YZ3 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1047017|uniprotkb:Q5U1F4|ensembl:ENSP00000357791|uniprotkb:Q5DT20 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:horn_human(display_long)|uniprotkb:HRNR(gene name)|psi-mi:HRNR(display_short)|uniprotkb:S100A18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001009931.1|ensembl:ENSG00000197915(gene)|ensembl:ENST00000368801(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031424"(keratinization)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0043163"(cell envelope organization)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR033201|interpro:IPR034325|mint:Q86YZ3|reactome:R-HSA-6798695|ensembl:ENSP00000357791 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:j5ATFM7OQGbf5j+CZpJ3bJoadnc9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q00059 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P68104 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P42704 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P15924 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|uniprotkb:D7RX09|ensembl:ENSP00000369129 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001305963.1|refseq:NP_001008844.1|refseq:NP_004406.2|go:"GO:0014704"(intercalated disc)|go:"GO:0005916"(fascia adherens)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-109N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P02545 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:O95071 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q13263 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P11021 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P0CG48 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-3390054|ensembl:ENSP00000344818|ensembl:ENSP00000441543|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5656121|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9613829|ensembl:ENSG00000150991(gene)|ensembl:ENST00000339647(transcript)|ensembl:ENST00000536769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:1ZO6|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|interpro:IPR000626(Ubiquitin)|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2MI8|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3PTF|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6EQI|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|refseq:NP_066289.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 intact:EBI-11820565 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 - psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:1304"(molecule set) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 - - - comment:P0DMV8,P0DMV9 figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 - - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P08107 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P61978 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P21333 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q04695 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-297873|ensembl:ENSP00000308452|uniprotkb:A5Z1M9|uniprotkb:A5Z1N0|uniprotkb:A5Z1N1|uniprotkb:A5Z1N2|uniprotkb:A6NDV6|uniprotkb:A6NKQ2|uniprotkb:Q6IP98|uniprotkb:Q8N1P6 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k1c17_human(display_long)|uniprotkb:KRT17(gene name)|psi-mi:KRT17(display_short)|uniprotkb:Cytokeratin-17(gene name synonym)|uniprotkb:39.1(gene name synonym)|uniprotkb:Keratin-17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000128422(gene)|ensembl:ENST00000311208(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031424"(keratinization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0071944"(cell periphery)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:Q04695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000413.1|dip:DIP-33093N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:cwKlvMqhQGUokThbIxgEkB6Wzxw9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P67936 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q93009 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P09493 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P07355 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P06753 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q75N03 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|intact:EBI-28973894|ensembl:ENSP00000401277|uniprotkb:B7ZM03 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENST00000222597|ensembl:ENSP00000222597|ensembl:ENSP00000401277|ensembl:ENSG00000105879(gene)|ensembl:ENST00000440859(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|refseq:NP_079090.2|refseq:NP_001271220.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P02768 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-714423|ensembl:ENSP00000295897|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:1E78|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051087"(chaperone binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7JWN|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-879518|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|rcsb pdb:6WUW|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:1E7A|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6HSC|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|refseq:NP_000468.1|dip:DIP-29902N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q9HCE5 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P01857 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-356114|ensembl:ENSP00000374991|ensembl:ENSP00000488387 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000211896(gene)|ensembl:ENSG00000277633(gene)|ensembl:ENST00000390549(transcript)|ensembl:ENST00000631466(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:1I7Z|rcsb pdb:3WJL|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:3WKN|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|reactome:R-HSA-166663|rcsb pdb:4XNZ|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:1YK8rrTDnOYYKW5wHI48/rYlr5o9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P11142 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q7Z794 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-3045529|intact:EBI-28984254|ensembl:ENSP00000342710|uniprotkb:Q7RTS8 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k2c1b_human(display_long)|uniprotkb:KRT77(gene name)|psi-mi:KRT77(display_short)|uniprotkb:KRT1B(gene name synonym)|uniprotkb:Cytokeratin-1B(gene name synonym)|uniprotkb:Keratin-77(gene name synonym)|uniprotkb:Type-II keratin Kb39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000189182(gene)|ensembl:ENST00000341809(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_778253.2|ensembl:ENSP00000342710 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:+gHbNvYkE7DhN5LqnFk9EY1/A409606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P08779 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-356410|uniprotkb:P30654|uniprotkb:Q16402|uniprotkb:Q9UBG8|uniprotkb:A8K488|ensembl:ENSP00000301653 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k1c16_human(display_long)|uniprotkb:KRT16(gene name)|psi-mi:KRT16(display_short)|uniprotkb:KRT16A(gene name synonym)|uniprotkb:Keratin-16(gene name synonym)|uniprotkb:Cytokeratin-16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_005548.2|ensembl:ENSG00000186832(gene)|ensembl:ENST00000301653(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007568"(aging)|go:"GO:0030216"(keratinocyte differentiation)|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031424"(keratinization)|go:"GO:0042633"(hair cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051546"(keratinocyte migration)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08779 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:NkPTLkWquNNlGYbrXaRkyRmKvmM9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P68032 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P04259 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-740907|ensembl:ENSP00000252252|uniprotkb:P48669 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k2c6b_human(display_long)|uniprotkb:Cytokeratin-6B(gene name synonym)|uniprotkb:Keratin-6B(gene name synonym)|uniprotkb:KRT6B(gene name)|psi-mi:KRT6B(display_short)|uniprotkb:K6B(gene name synonym)|uniprotkb:KRTL1(gene name synonym)|uniprotkb:Type-II keratin Kb10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_005546.2|ensembl:ENSG00000185479(gene)|ensembl:ENST00000252252(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0007398"(ectoderm development)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P04259|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:lFuNGZdQm4pftz53qbflLTyyAaQ9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q86U44 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P38646 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P02533 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-702178|uniprotkb:Q14715|uniprotkb:Q53XY3|uniprotkb:Q9BUE3|uniprotkb:Q9UBN2|uniprotkb:Q9UBN3|uniprotkb:Q9UCY4|ensembl:ENSP00000167586 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k1c14_human(display_long)|uniprotkb:Cytokeratin-14(gene name synonym)|uniprotkb:KRT14(gene name)|psi-mi:KRT14(display_short)|uniprotkb:Keratin-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_000517.2|dip:DIP-33874N|ensembl:ENSG00000186847(gene)|ensembl:ENST00000167586(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0008544"(epidermis development)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042633"(hair cycle)|go:"GO:0045095"(keratin filament)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990254"(keratin filament binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P02533|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:IO1k6S8FB65jQr4GNwhKuxZ1ohg9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q5T200 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2679720|uniprotkb:Q7Z7J3|uniprotkb:Q5T1Z9|uniprotkb:O94936|uniprotkb:Q9H0L6|uniprotkb:Q8NDT6|uniprotkb:A2A323|ensembl:ENSP00000242848 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:zc3hd_human(display_long)|uniprotkb:KIAA0853(gene name synonym)|uniprotkb:ZC3H13(gene name)|psi-mi:ZC3H13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_055885.3|refseq:XP_005266369.1|ensembl:ENSG00000123200(gene)|ensembl:ENST00000242848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|mint:Q5T200|refseq:NP_001070256.1|refseq:NP_001317493.1|refseq:NP_001317494.1|refseq:NP_001317495.1|refseq:NP_001317496.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:uqLw8ZjXiweaBggvvS1ue4FvNf09606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P02538 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-702198|uniprotkb:P48667|uniprotkb:Q08AR4|uniprotkb:Q6NT67|uniprotkb:Q96CL4|uniprotkb:A4QPC1|ensembl:ENSP00000369317 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k2c6a_human(display_long)|uniprotkb:Cytokeratin-6A(gene name synonym)|uniprotkb:Keratin-6A(gene name synonym)|uniprotkb:Cytokeratin-6D(gene name synonym)|uniprotkb:KRT6A(gene name)|psi-mi:KRT6A(display_short)|uniprotkb:K6A(gene name synonym)|uniprotkb:KRT6D(gene name synonym)|uniprotkb:Type-II keratin Kb6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_005545.1|dip:DIP-533N|ensembl:ENSG00000205420(gene)|ensembl:ENST00000330722(transcript)|go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042060"(wound healing)|go:"GO:0045095"(keratin filament)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P02538|rcsb pdb:5KI0|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:feIxUFTSMnjattUda5vdGhiL9H89606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q05682 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P13647 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-702187|uniprotkb:Q6PI71|uniprotkb:Q6UBJ0|uniprotkb:Q8TA91|ensembl:ENSP00000252242 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k2c5_human(display_long)|uniprotkb:Cytokeratin-5(gene name synonym)|uniprotkb:58 kDa cytokeratin(gene name synonym)|uniprotkb:KRT5(gene name)|psi-mi:KRT5(display_short)|uniprotkb:Keratin-5(gene name synonym)|uniprotkb:Type-II keratin Kb5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_000415.2|dip:DIP-39N|ensembl:ENSG00000186081(gene)|ensembl:ENST00000252242(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P13647|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:BdtVgSlWFYS/+zyXLNxvrcSWc4I9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P60709 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P35527 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-356382|uniprotkb:O00109|uniprotkb:Q0IJ47|uniprotkb:Q14665|ensembl:ENSP00000246662 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k1c9_human(display_long)|uniprotkb:KRT9(gene name)|psi-mi:KRT9(display_short)|uniprotkb:Keratin-9(gene name synonym)|uniprotkb:Cytokeratin-9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_000217.2|ensembl:ENSG00000171403(gene)|ensembl:ENST00000246662(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0043588"(skin development)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P35527|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:m4EXfxbK2t1/EmI04YODKTJ02Zw9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P35908 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-1247312|uniprotkb:Q4VAQ2|ensembl:ENSP00000310861 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k22e_human(display_long)|uniprotkb:KRT2(gene name)|psi-mi:KRT2(display_short)|uniprotkb:KRT2A(gene name synonym)|uniprotkb:KRT2E(gene name synonym)|uniprotkb:Cytokeratin-2e(gene name synonym)|uniprotkb:Keratin-2e(gene name synonym)|uniprotkb:Type-II keratin Kb2(gene name synonym)|uniprotkb:Keratin-2 epidermis(gene name synonym)|uniprotkb:Epithelial keratin-2e(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_000414.2|ensembl:ENSG00000172867(gene)|ensembl:ENST00000309680(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003334"(keratinocyte development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|go:"GO:0032980"(keratinocyte activation)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045095"(keratin filament)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P35908|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0051546"(keratinocyte migration) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:T7LeB8nkZzNjUb8DWdkxbrl5f789606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P13645 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-465144|ensembl:ENSP00000269576|uniprotkb:Q14664|uniprotkb:Q8N175 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k1c10_human(display_long)|uniprotkb:KRT10(gene name)|psi-mi:KRT10(display_short)|uniprotkb:Cytokeratin-10(gene name synonym)|uniprotkb:KPP(gene name synonym)|uniprotkb:Keratin-10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000186395(gene)|ensembl:ENST00000269576(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P13645|rcsb pdb:3ASW|rcsb pdb:4F1Z|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6EC0|rcsb pdb:6UUI|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000412.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:z100yyq3b63P0ARy2lE2ELyJeik9606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:Q69YN4 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15007 uniprotkb:P04264 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-298429|uniprotkb:Q14720|uniprotkb:Q6GSJ0|uniprotkb:B2RA01|uniprotkb:Q9H298|ensembl:ENSP00000252244|uniprotkb:P85925|uniprotkb:P86104 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:k2c1_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:KRTA(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Cytokeratin-1(gene name synonym)|uniprotkb:67 kDa cytokeratin(gene name synonym)|uniprotkb:Hair alpha protein(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595349|imex:IM-26525-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_006112.3|ensembl:ENSG00000167768(gene)|ensembl:ENST00000252244(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045095"(keratin filament)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR032449|interpro:IPR039008|mint:P04264|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6UUI|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2020/10/15 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:TeAC3i2hWTS2lgXT0i4agp9nv349606 - false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q8N726 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-625922|uniprotkb:Q13195|uniprotkb:Q13399|uniprotkb:Q16360|uniprotkb:Q7KZR9|ensembl:ENSP00000432664|ensembl:ENSP00000462950|uniprotkb:D3DRK2 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:arf_human(display_long)|uniprotkb:p14ARF(gene name synonym)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:MLM(gene name synonym)|uniprotkb:Alternative reading frame(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000147889(gene)|ensembl:ENST00000530628(transcript)|ensembl:ENST00000579755(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0050821"(protein stabilization)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090398"(cellular senescence)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)|mint:Q8N726|reactome:R-HSA-111471|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-6804757|reactome:R-HSA-69541|reactome:R-HSA-8941858|reactome:R-HSA-9645722|reactome:R-HSA-9646303|reactome:R-HSA-9646304|refseq:NP_478102.2|dip:DIP-24171N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:zdbvJmkrI/zJFL+Enq5jTM1Csdw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q6P2Q9 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-538479|uniprotkb:O14547|uniprotkb:O75965|ensembl:ENSP00000304350|ensembl:ENSP00000460348|ensembl:ENSP00000479194|ensembl:ENSP00000488611 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:prp8_human(display_long)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:PRP8 homolog(gene name synonym)|uniprotkb:220 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:p220(gene name synonym)|uniprotkb:PRPC8(gene name synonym)|uniprotkb:PRPF8(gene name)|psi-mi:PRPF8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006436.3|ensembl:ENSG00000174231(gene)|ensembl:ENSG00000274442(gene)|ensembl:ENST00000304992(transcript)|ensembl:ENST00000572621(transcript)|ensembl:ENST00000614672(transcript)|ensembl:ENST00000634039(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q6P2Q9|rcsb pdb:3E9L|rcsb pdb:3ENB|rcsb pdb:3JCR|rcsb pdb:3LRU|rcsb pdb:4JK7|rcsb pdb:4JK8|rcsb pdb:4JK9|rcsb pdb:4JKA|rcsb pdb:4JKB|rcsb pdb:4JKC|rcsb pdb:4JKD|rcsb pdb:4JKE|rcsb pdb:4JKF|rcsb pdb:4JKG|rcsb pdb:4JKH|rcsb pdb:4KIT|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5XJC|dip:DIP-29614N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:I0ot8b3pvieXRI66omFm145sGVA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P00403 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P53999 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-998260|uniprotkb:Q96L29|ensembl:ENSP00000265073|ensembl:ENSP00000422078|ensembl:ENSP00000422806|ensembl:ENSP00000426850|ensembl:ENSP00000427100 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tcp4_human(display_long)|uniprotkb:SUB1 homolog(gene name synonym)|uniprotkb:Positive cofactor 4(gene name synonym)|uniprotkb:p14(gene name synonym)|uniprotkb:SUB1(gene name)|psi-mi:SUB1(display_short)|uniprotkb:PC4(gene name synonym)|uniprotkb:RPO2TC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:XP_011512246.1|ensembl:ENSG00000113387(gene)|ensembl:ENST00000265073(transcript)|ensembl:ENST00000502897(transcript)|ensembl:ENST00000506237(transcript)|ensembl:ENST00000512913(transcript)|ensembl:ENST00000515355(transcript)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003173(Transcriptional coactivator p15)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|mint:P53999|rcsb pdb:1PCF|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|rcsb pdb:2C62|rcsb pdb:2PHE|rcsb pdb:4USG|go:"GO:0003697"(single-stranded DNA binding)|rcsb pdb:6YCS|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0051053"(negative regulation of DNA metabolic process)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|refseq:NP_006704.3|refseq:XP_016864475.1|refseq:XP_016864476.1|dip:DIP-29044N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:FqBKBuLmQS+idbd68EdKsTCzPg89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q7Z6Z7 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q68DL7 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-11323181|uniprotkb:A6NME8|ensembl:ENSP00000464330 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cr063_human(display_long)|uniprotkb:C18orf63(gene name)|psi-mi:C18orf63(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001167594.1|ensembl:ENSG00000206043(gene)|ensembl:ENST00000579455(transcript)|interpro:IPR031643 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:PJOEDQ5xaJ+48HJclZUnMLlpabA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P01602 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2371313|uniprotkb:A0A075B6S8|intact:EBI-4286966|uniprotkb:P01596|uniprotkb:P01598|uniprotkb:P01604|ensembl:ENSP00000420436|ensembl:ENSP00000488639 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:kv105_human(display_long)|uniprotkb:IGKV1-5(gene name)|psi-mi:IGKV1-5(display_short)|uniprotkb:Ig kappa chain V-I region HK102(gene name synonym)|uniprotkb:Ig kappa chain V-I region CAR(gene name synonym)|uniprotkb:Ig kappa chain V-I region EU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Kue(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000243466(gene)|ensembl:ENSG00000282801(gene)|ensembl:ENST00000496168(transcript)|ensembl:ENST00000632205(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:WKovn0mvryvDbJqn6iNbiFvN+rw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P01593 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-20594941|uniprotkb:P01613|uniprotkb:P80362|uniprotkb:A0A0B4J1U0|uniprotkb:P01595|uniprotkb:P01605|uniprotkb:P01607|uniprotkb:P01608|uniprotkb:P01609|ensembl:ENSP00000374800 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:kvd33_human(display_long)|uniprotkb:Ig kappa chain V-I region AG(gene name synonym)|uniprotkb:Ig kappa chain V-I region Bi(gene name synonym)|uniprotkb:Ig kappa chain V-I region Lay(gene name synonym)|uniprotkb:Ig kappa chain V-I region Ni(gene name synonym)|uniprotkb:Ig kappa chain V-I region Rei(gene name synonym)|uniprotkb:Ig kappa chain V-I region Roy(gene name synonym)|uniprotkb:Ig kappa chain V-I region Scw(gene name synonym)|uniprotkb:Ig kappa chain V-I region WAT(gene name synonym)|uniprotkb:IGKV1D-33(gene name)|psi-mi:IGKV1D-33(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000239975(gene)|ensembl:ENST00000390265(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1AR2|rcsb pdb:1BWW|rcsb pdb:1REI|rcsb pdb:1WTL|rcsb pdb:4L1H|rcsb pdb:5XP1|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:+8FNYvbRPCc9GI9G4Tf+BdsBnd49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9Y4Z0 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-372521|ensembl:ENSP00000469468 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:lsm4_human(display_long)|uniprotkb:Glycine-rich protein(gene name synonym)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_036453.1|ensembl:ENSG00000130520(gene)|ensembl:ENST00000593829(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033962"(P-body assembly)|go:"GO:0042731"(PH domain binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0043005"(neuron projection)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|dip:DIP-31209N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:FlaQveuBbixGvfX47pCm26xscT09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9Y3U8 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9Y2X3 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9UKM9 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-714796|uniprotkb:Q14621|uniprotkb:Q2M365|uniprotkb:Q5QPL8|uniprotkb:Q9BQX6|uniprotkb:Q9UJE3|ensembl:ENSP00000246194 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:raly_human(display_long)|uniprotkb:hnRNP associated with lethal yellow protein homolog(gene name synonym)|uniprotkb:Autoantigen p542(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 2(gene name synonym)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)|uniprotkb:P542(gene name synonym)|uniprotkb:HNRPCL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:XP_011526996.1|refseq:XP_011526997.1|ensembl:ENSG00000125970(gene)|ensembl:ENST00000246194(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR034502|interpro:IPR035979|mint:Q9UKM9|rcsb pdb:1WF1|refseq:NP_031393.2|refseq:NP_057951.1|refseq:XP_005260391.1|refseq:XP_005260393.1|refseq:XP_016883220.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:3hd0n2UW0FSRNvSJa2mqflVeorc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9UHX1 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9UHB6 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351479|uniprotkb:Q2TAN7|uniprotkb:Q9BVF2|uniprotkb:Q9H8J1|uniprotkb:Q9HBN5|uniprotkb:Q9NX96|uniprotkb:Q9NXC3|uniprotkb:Q9NXU6|uniprotkb:Q9P0H8|uniprotkb:Q9UHB5|uniprotkb:B2RB09|ensembl:ENSP00000340184|uniprotkb:Q59FE8 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:lima1_human(display_long)|uniprotkb:PP624(orf name)|uniprotkb:LIMA1(gene name)|psi-mi:LIMA1(display_short)|uniprotkb:SREBP3(gene name synonym)|uniprotkb:Epithelial protein lost in neoplasm(gene name synonym)|uniprotkb:EPLIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001107018.1|refseq:NP_001107019.1|refseq:NP_057441.1|refseq:XP_011536757.1|ensembl:ENSG00000050405(gene)|ensembl:ENST00000341247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031526"(brush border membrane)|go:"GO:0031529"(ruffle organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028740|mint:Q9UHB6|rcsb pdb:2D8Y|refseq:NP_001230704.1|refseq:XP_016874919.1|dip:DIP-29633N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:sHqhe21LVzLJXgDMH6IcWukKNHE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9NQC3 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-715945|intact:EBI-1753019|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y2Y7|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|ensembl:ENSP00000337838|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENST00000317610|ensembl:ENSP00000322147|ensembl:ENSP00000337838|ensembl:ENST00000357376|ensembl:ENSP00000349944|ensembl:ENST00000357732|ensembl:ENSP00000350365|ensembl:ENST00000394609|ensembl:ENSP00000378107|ensembl:ENST00000394611|ensembl:ENSP00000378109|ensembl:ENST00000404909|ensembl:ENSP00000385650|ensembl:ENST00000405240|ensembl:ENSP00000384471|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|ensembl:ENSG00000115310(gene)|ensembl:ENST00000337526(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:XP_005264491.1|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9HCU9 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-714781|uniprotkb:Q6IAI2|ensembl:ENSP00000353042 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:brms1_human(display_long)|uniprotkb:BRMS1(gene name)|psi-mi:BRMS1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000174744(gene)|ensembl:ENST00000359957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR013907(Sds3-like)|rcsb pdb:2XUS|rcsb pdb:4AUV|reactome:R-HSA-3214815|reactome:R-HSA-9679191|refseq:NP_056214.1|dip:DIP-24250N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:kuaR4dVP6xzSOMHwSd+CDrLU/uo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9C037 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-4307604|uniprotkb:Q9C036|uniprotkb:Q96F06|uniprotkb:A4D298|uniprotkb:Q75MK1|ensembl:ENSP00000348216 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:trim4_human(display_long)|uniprotkb:TRIM4(gene name)|psi-mi:TRIM4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM4(gene name synonym)|uniprotkb:Tripartite motif-containing protein 4(gene name synonym)|uniprotkb:RNF87(gene name synonym)|uniprotkb:RING finger protein 87(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_148977.2|refseq:NP_149082.1|ensembl:ENST00000355947(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000146833(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035829|interpro:IPR043136|reactome:R-HSA-983168 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:x0Ig4/YAD4KeGptdNhCbmNxsbas9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q99873 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q99848 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q99729 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q99623 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:h4pib54mBeQgOKCe/hib58LM26w9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q96S55 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2513471|ensembl:ENSP00000370150|ensembl:ENSP00000477551|uniprotkb:Q9NRJ6|uniprotkb:Q5W0E2|uniprotkb:Q53EP6|uniprotkb:Q8WV26|uniprotkb:Q5W0E4|uniprotkb:Q59ET8|uniprotkb:Q9H681|uniprotkb:B2RDB0 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:wrip1_human(display_long)|uniprotkb:WRNIP1(gene name)|psi-mi:WRNIP1(display_short)|uniprotkb:WHIP(gene name synonym)|uniprotkb:Werner helicase-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000124535(gene)|ensembl:ENST00000380773(transcript)|ensembl:ENST00000618555(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|interpro:IPR040539|mint:Q96S55|rcsb pdb:3VHS|rcsb pdb:3VHT|go:"GO:0017116"(single-stranded DNA helicase activity)|refseq:NP_064520.2|refseq:NP_569079.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Q8qVSqItgTO7sbWGAQ3XAoFFUr89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q96P63 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2553395|uniprotkb:Q3SYB4|ensembl:ENSP00000269491 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:spb12_human(display_long)|uniprotkb:SERPINB12(gene name)|psi-mi:SERPINB12(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001294857.1|refseq:XP_011524550.1|refseq:XP_011524551.1|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:Q96P63|reactome:R-HSA-6798695|refseq:NP_536722.1|ensembl:ENSG00000166634(gene)|ensembl:ENST00000269491(transcript)|refseq:XP_016881556.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:rjDNYwceRueAXnaDN3nJNMqwRxM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q96AG4 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q92499 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358474|ensembl:ENSP00000233084|ensembl:ENSP00000370745|ensembl:ENSP00000413767|ensembl:ENSP00000504080|uniprotkb:B4DME8|uniprotkb:B4DPN6 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ddx1_human(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:DEAD box protein retinoblastoma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000079785(gene)|ensembl:ENST00000233084(transcript)|ensembl:ENST00000381341(transcript)|ensembl:ENST00000434671(transcript)|ensembl:ENST00000677302(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|refseq:NP_004930.1|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071920"(cleavage body)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR043136|mint:Q92499|rcsb pdb:4XW3|reactome:R-HSA-6784531|dip:DIP-38163N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:n2Zv07BpuUDT32/ttDzIFXH3yIQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q8WUF8 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2556079|uniprotkb:Q9H0U8|uniprotkb:B2R7C6|uniprotkb:B4DJ14|uniprotkb:B4DLG5|ensembl:ENSP00000379294 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:f172a_human(display_long)|uniprotkb:C5orf21(gene name synonym)|uniprotkb:FAM172A(gene name)|psi-mi:FAM172A(display_short)|uniprotkb:Protein FAM172A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001156889.1|refseq:NP_001156890.1|refseq:NP_114431.2|refseq:XP_011541974.1|refseq:XP_006714780.1|refseq:XP_016865444.1|refseq:XP_016865445.1|ensembl:ENSG00000113391(gene)|ensembl:ENST00000395965(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014032"(neural crest cell development)|go:"GO:0031048"(heterochromatin assembly by small RNA)|interpro:IPR029058|interpro:IPR039929 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:6bDzV1sfpO3EGQ74VuWXY9g5p5A9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q8TEM1 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q8TDN6 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_060791.3|ensembl:ENSG00000113460(gene)|ensembl:ENST00000336767(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q8NC51 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q86UP2 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q7L014 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2555356|uniprotkb:Q96EI0|uniprotkb:O94894|uniprotkb:Q9Y658|ensembl:ENSP00000346236 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ddx46_human(display_long)|uniprotkb:KIAA0801(gene name synonym)|uniprotkb:DEAD box protein 46(gene name synonym)|uniprotkb:PRP5 homolog(gene name synonym)|uniprotkb:DDX46(gene name)|psi-mi:DDX46(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_055644.2|ensembl:ENSG00000145833(gene)|ensembl:ENST00000354283(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q7L014|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|reactome:R-HSA-72163|refseq:NP_001287789.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:spn1NOUIO6XjH4RRbtPsBgR5Wk09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q6PIJ6 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2513135|ensembl:ENSP00000342023|uniprotkb:Q9HC40|uniprotkb:Q86VN3|uniprotkb:Q7Z2U0|uniprotkb:Q9H837|uniprotkb:Q9BXY6|uniprotkb:Q6PK72 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:fbx38_human(display_long)|uniprotkb:FBXO38(gene name)|psi-mi:FBXO38(display_short)|uniprotkb:SP329(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|interpro:IPR042354|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000145868(gene)|ensembl:ENST00000340253(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|refseq:NP_110420.3|refseq:NP_001258652.1|refseq:XP_005268570.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/j2W7mAL7RdWukKthtgCaX3cV3k9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q5T750 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2563033|ensembl:ENSP00000357764|uniprotkb:O14634 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:xp32_human(display_long)|uniprotkb:XP32(gene name)|psi-mi:XP32(display_short)|uniprotkb:C1orf68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001019850.1|ensembl:ENSG00000198854(gene)|ensembl:ENST00000368775(transcript)|go:"GO:0008544"(epidermis development)|interpro:IPR026078|mint:Q5T750 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:QHKngjyz/pqUrpu1XJ8NINDtmm49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q5T749 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-10981970|ensembl:ENSP00000475216 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:kprp_human(display_long)|uniprotkb:KPRP(gene name)|psi-mi:KPRP(display_short)|uniprotkb:C1orf45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001020402.1|refseq:XP_011507873.1|ensembl:ENSG00000203786(gene)|ensembl:ENST00000606109(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0070062"(extracellular exosome)|mint:Q5T749 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:y5a5hbvzlv8VDmCY169of+RrNKo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q5T2N8 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2880061|ensembl:ENSP00000368062|uniprotkb:Q8N1Z5 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:atd3c_human(display_long)|uniprotkb:ATAD3C(gene name)|psi-mi:ATAD3C(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000215915(gene)|ensembl:ENST00000378785(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T2N8|refseq:NP_001034300.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:JP1/f7Mg8jNYnXeYRsoIxhk6t+s9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q5T200 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2679720|uniprotkb:Q7Z7J3|uniprotkb:Q5T1Z9|uniprotkb:O94936|uniprotkb:Q9H0L6|uniprotkb:Q8NDT6|uniprotkb:A2A323|ensembl:ENSP00000242848 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:zc3hd_human(display_long)|uniprotkb:KIAA0853(gene name synonym)|uniprotkb:ZC3H13(gene name)|psi-mi:ZC3H13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_055885.3|refseq:XP_005266369.1|ensembl:ENSG00000123200(gene)|ensembl:ENST00000242848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|mint:Q5T200|refseq:NP_001070256.1|refseq:NP_001317493.1|refseq:NP_001317494.1|refseq:NP_001317495.1|refseq:NP_001317496.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:uqLw8ZjXiweaBggvvS1ue4FvNf09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q5RHP9 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2681211|uniprotkb:Q8ND41|uniprotkb:Q6GMR8|uniprotkb:Q68DL8|uniprotkb:Q6ZSF9|ensembl:ENSP00000322609 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:eric3_human(display_long)|uniprotkb:ERICH3(gene name)|psi-mi:ERICH3(display_short)|uniprotkb:C1orf173(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001002912.4|refseq:XP_016855763.1|refseq:XP_016855767.1|refseq:XP_016855768.1|refseq:XP_016855769.1|refseq:XP_016855770.1|refseq:XP_016855771.1|refseq:XP_016855772.1|refseq:XP_016855773.1|refseq:XP_016855774.1|ensembl:ENSG00000178965(gene)|ensembl:ENST00000326665(transcript)|interpro:IPR027962 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:MbJ5ICx1bYgjOcXRlg7Lkr8ZkPU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q16658 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351076|uniprotkb:Q96IH1|uniprotkb:A6NI89|uniprotkb:Q96IC5|uniprotkb:Q9BRF1|uniprotkb:B2RE97|ensembl:ENSP00000371798 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:fscn1_human(display_long)|uniprotkb:FSCN1(gene name)|psi-mi:FSCN1(display_short)|uniprotkb:FAN1(gene name synonym)|uniprotkb:HSN(gene name synonym)|uniprotkb:SNL(gene name synonym)|uniprotkb:Singed-like protein(gene name synonym)|uniprotkb:55 kDa actin-bundling protein(gene name synonym)|uniprotkb:p55(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0044393"(microspike)|go:"GO:0045296"(cadherin binding)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010431(Fascin)|interpro:IPR022768|interpro:IPR024703|interpro:IPR030146|mint:Q16658|rcsb pdb:1DFC|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030035"(microspike assembly)|rcsb pdb:3LLP|refseq:NP_003079.1|ensembl:ENSG00000075618(gene)|ensembl:ENST00000382361(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008144"(obsolete drug binding)|rcsb pdb:3P53|rcsb pdb:4GOV|rcsb pdb:4GOY|rcsb pdb:4GP3|rcsb pdb:6B0T|rcsb pdb:6I0Z|rcsb pdb:6I10|rcsb pdb:6I11|rcsb pdb:6I12|rcsb pdb:6I13|rcsb pdb:6I14|rcsb pdb:6I15|rcsb pdb:6I16|rcsb pdb:6I17|rcsb pdb:6I18|reactome:R-HSA-6785807|rcsb pdb:4GP0|dip:DIP-33171N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:yc9EJDCKGJGGEcEueR/yAY/fxRg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q16630 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_008938.2|refseq:NP_001287876.1|ensembl:ENSG00000111605(gene)|ensembl:ENST00000435070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042382"(paraspeckles)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990448"(exon-exon junction complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|reactome:R-HSA-1839117|reactome:R-HSA-5655302|dip:DIP-34501N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q16576 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15427 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15369 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q14978 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q14697 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-348004|ensembl:ENSP00000349053|uniprotkb:A6NC20|uniprotkb:Q8WTS9|uniprotkb:Q9P0X0 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ganab_human(display_long)|uniprotkb:GANAB(gene name)|psi-mi:GANAB(display_short)|uniprotkb:G2AN(gene name synonym)|uniprotkb:KIAA0088(gene name synonym)|uniprotkb:Glucosidase II subunit alpha(gene name synonym)|uniprotkb:Alpha-glucosidase 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000089597(gene)|ensembl:ENST00000356638(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006491"(N-glycan processing)|go:"GO:0016020"(membrane)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0033919"(glucan 1,3-alpha-glucosidase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090599"(alpha-glucosidase activity)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|mint:Q14697|reactome:R-HSA-532668|reactome:R-HSA-901042|reactome:R-HSA-9694548|reactome:R-HSA-9683686|refseq:NP_938148.1|refseq:NP_938149.2|refseq:NP_001265121.1|refseq:NP_001265122.1|refseq:NP_001265123.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:663u1GYwNTZrodoVqwzFjSDGCqs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13867 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13765 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-712216|ensembl:ENSP00000349212|ensembl:ENSP00000377469|ensembl:ENSP00000446801|ensembl:ENSP00000447821|ensembl:ENSP00000503345|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|uniprotkb:F8VU71 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000196531(gene)|ensembl:ENST00000356769(transcript)|ensembl:ENST00000393891(transcript)|ensembl:ENST00000546392(transcript)|ensembl:ENST00000552540(transcript)|ensembl:ENST00000678066(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006412"(translation)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0015031"(protein transport)|go:"GO:0042060"(wound healing)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901227"(negative regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|go:"GO:0043403"(skeletal muscle tissue regeneration)|refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13435 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-749111|uniprotkb:A8K485|uniprotkb:B4DT19|uniprotkb:Q7Z627|uniprotkb:Q969K1|uniprotkb:Q96CM6|uniprotkb:Q9BWD2|intact:EBI-1052093|intact:EBI-2688256|uniprotkb:Q7L4T5|ensembl:ENSP00000318861 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sf3b2_human(display_long)|uniprotkb:SF3B2(gene name)|psi-mi:SF3B2(display_short)|uniprotkb:SAP145(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 145 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 145(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006833.2|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006568(PSP, proline-rich)|ensembl:ENSG00000087365(gene)|ensembl:ENST00000322535(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR007180(Protein of unknown function DUF382)|rcsb pdb:2DO5|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|mint:Q13435|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Y9uCV2x4J5kqyxeO8iXjojkXocA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13410 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2372803|uniprotkb:Q4VAN4|uniprotkb:Q9H458|uniprotkb:Q4VAN3|ensembl:ENSP00000244513|ensembl:ENSP00000507193 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:bt1a1_human(display_long)|uniprotkb:BTN1A1(gene name)|psi-mi:BTN1A1(display_short)|uniprotkb:BTN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001723.2|ensembl:ENSG00000124557(gene)|ensembl:ENST00000244513(transcript)|ensembl:ENST00000684113(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037958|interpro:IPR043136|reactome:R-HSA-8851680 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:3vJxfUEU8CgKp6iDHJvVC/2KNNU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13247 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-745230|uniprotkb:Q13244|uniprotkb:Q13245|uniprotkb:Q96J06|uniprotkb:Q9UJB8|uniprotkb:Q9Y3N7|uniprotkb:B7Z6J3|uniprotkb:E1P5W6|ensembl:ENSP00000244020 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:srsf6_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:SRSF6(gene name)|psi-mi:SRSF6(display_short)|uniprotkb:SRP55(gene name synonym)|uniprotkb:SFRS6(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006266.2|ensembl:ENSG00000124193(gene)|ensembl:ENST00000244020(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:Q13247|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:vU4nobP3g/hsgnll0mQgjJcME2k9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13185 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q12931 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q12874 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:fNjNguUOXqApr46rOAEpTs2geqY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q10713 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2514696|ensembl:ENSP00000360782|uniprotkb:Q8N513|uniprotkb:Q16639|uniprotkb:Q5SXM9|uniprotkb:B4DKL3|uniprotkb:E7ET61 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:mppa_human(display_long)|uniprotkb:PMPCA(gene name)|psi-mi:PMPCA(display_short)|uniprotkb:INPP5E(gene name synonym)|uniprotkb:KIAA0123(gene name synonym)|uniprotkb:MPPA(gene name synonym)|uniprotkb:Alpha-MPP(gene name synonym)|uniprotkb:P-55(gene name synonym)|uniprotkb:Inactive zinc metalloprotease alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001269875.1|ensembl:ENSG00000165688(gene)|ensembl:ENST00000371717(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-HSA-1268020|reactome:R-HSA-8949664|interpro:IPR037715|refseq:NP_001269873.1|refseq:NP_055975.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Kqz7qIyX2eUOcnNrfIsSPjc4Isw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q09666 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q08554 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2371346|uniprotkb:Q9HB01|ensembl:ENSP00000257198 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:dsc1_human(display_long)|uniprotkb:DSC1(gene name)|psi-mi:DSC1(display_short)|uniprotkb:CDHF1(gene name synonym)|uniprotkb:Desmosomal glycoprotein 2/3(gene name synonym)|uniprotkb:Cadherin family member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004939.1|refseq:NP_077739.1|ensembl:ENSG00000134765(gene)|ensembl:ENST00000257198(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030057"(desmosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|rcsb pdb:5IRY|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:dxtPfdDnZFaelPwT5bV8k/ZobSw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q02543 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-350523|ensembl:ENSP00000222247 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl18a_human(display_long)|uniprotkb:RPL18A(gene name)|psi-mi:RPL18A(display_short)|uniprotkb:Large ribosomal subunit protein eL20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000971.1|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:Q02543|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|go:"GO:0097327"(response to antineoplastic agent)|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|ensembl:ENSG00000105640(gene)|ensembl:ENST00000222247(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6ZME|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:O9XdW7Let2GcJpJLVuUtatVVv1I9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q00325 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P84098 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-916524|uniprotkb:P14118|uniprotkb:P22908|uniprotkb:Q502Y6|uniprotkb:Q7Z6E4|uniprotkb:B2R4K2|ensembl:ENSP00000225430 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl19_human(display_long)|uniprotkb:RPL19(gene name)|psi-mi:RPL19(display_short)|uniprotkb:Large ribosomal subunit protein eL19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000972.1|ensembl:ENSG00000108298(gene)|ensembl:ENST00000225430(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84098|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P67809 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P63244 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P63241 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62917 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62913 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354380|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q8TDH2|uniprotkb:Q9Y674|ensembl:ENSP00000496250 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl11_human(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000966.2|refseq:NP_001186731.1|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62913|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XXB|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y6X - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62899 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1053664|intact:EBI-3867511|uniprotkb:B7Z4K2|uniprotkb:P12947|uniprotkb:Q53SQ5|uniprotkb:Q6LBJ6|uniprotkb:D3DVJ4|uniprotkb:Q6IRZ0|ensembl:ENSP00000264258|ensembl:ENSP00000386681 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl31_human(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)|uniprotkb:Large ribosomal subunit protein eL31(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000984.1|refseq:NP_001092047.1|refseq:NP_001093163.1|ensembl:ENSG00000071082(gene)|ensembl:ENST00000264258(transcript)|ensembl:ENST00000409733(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62899|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:77LFR7/2somk6blVogZf1XFdJLk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62854 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62829 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62753 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:beDuXCIqL99V9JlVfpzx7MdpH689606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62316 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62314 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62304 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62280 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62277 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351850|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|uniprotkb:Q498Y0|uniprotkb:B2R549|ensembl:ENSP00000435777 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs13_human(display_long)|uniprotkb:RPS13(gene name)|psi-mi:RPS13(display_short)|uniprotkb:Small ribosomal subunit protein uS15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001008.1|ensembl:ENSG00000110700(gene)|ensembl:ENST00000525634(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62277|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6OM7|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62269 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62249 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352480|uniprotkb:P17008|uniprotkb:B2RDD5|ensembl:ENSP00000251453 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs16_human(display_long)|uniprotkb:RPS16(gene name)|psi-mi:RPS16(display_short)|uniprotkb:Small ribosomal subunit protein uS9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001011.1|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000105193(gene)|ensembl:ENST00000251453(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62249|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|dip:DIP-33200N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:OrKriR6HsATLaO+drdUa2w3Gpd09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62244 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-347895|ensembl:ENSP00000318646|ensembl:ENSP00000457000|ensembl:ENSP00000458115|ensembl:ENSP00000458528|uniprotkb:P39027|uniprotkb:P39031|uniprotkb:Q3MHD9|uniprotkb:Q8C023|uniprotkb:Q9BV24 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs15a_human(display_long)|uniprotkb:RPS15A(gene name)|psi-mi:RPS15A(display_short)|uniprotkb:Small ribosomal subunit protein uS8(gene name synonym)|uniprotkb:OK/SW-cl.82(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000134419(gene)|ensembl:ENST00000322989(transcript)|ensembl:ENST00000563390(transcript)|ensembl:ENST00000565420(transcript)|ensembl:ENST00000572008(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045787"(positive regulation of cell cycle)|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|go:"GO:0070062"(extracellular exosome)|rcsb pdb:6G4W|interpro:IPR000630(Ribosomal protein S8)|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|interpro:IPR035987|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|mint:P62244|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:4V6X|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-72695|reactome:R-HSA-975957|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZM7|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|refseq:NP_001010.2|refseq:NP_001025180.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Qdnhk7yvoFFYcRq5kEi7GQILaxs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P61313 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P61158 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P60660 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P51572 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-77683|ensembl:ENSP00000343458|ensembl:ENSP00000494052|ensembl:ENSP00000499882|uniprotkb:Q13836|uniprotkb:Q96CF0|uniprotkb:D3DWV5|uniprotkb:B3KQ79 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:bap31_human(display_long)|uniprotkb:BCAP31(gene name)|psi-mi:BCAP31(display_short)|uniprotkb:BAP31(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:6C6-AG tumor-associated antigen(gene name synonym)|uniprotkb:DXS1357E(gene name synonym)|uniprotkb:Protein CDM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001132913.1|refseq:NP_005736.3|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:P51572|rcsb pdb:4JZL|rcsb pdb:4JZP|reactome:R-HSA-111465|reactome:R-HSA-75153|reactome:R-HSA-8980692|reactome:R-HSA-983170|ensembl:ENSG00000185825(gene)|ensembl:ENST00000345046(transcript)|ensembl:ENST00000647529(transcript)|ensembl:ENST00000672675(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044877"(protein-containing complex binding)|refseq:NP_001243376.1|refseq:NP_001132929.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:m0aN00PLZJDWA/K1vEbla1W9+S89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P50914 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356746|uniprotkb:Q45RF0|uniprotkb:Q53G20|uniprotkb:Q8TBD5|uniprotkb:Q8WUT0|uniprotkb:Q92579|uniprotkb:Q96GR0|uniprotkb:Q9BSB8|uniprotkb:Q9BW65|uniprotkb:Q9BYF6|ensembl:ENSP00000345156|ensembl:ENSP00000379506 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl14_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short)|uniprotkb:CAG-ISL 7(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001030168.1|refseq:NP_003964.3|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|ensembl:ENSG00000188846(gene)|ensembl:ENST00000338970(transcript)|ensembl:ENST00000396203(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041985|mint:P50914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|interpro:IPR039660|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y2L - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:AjaguD5hgHtcBbJq5QfuG6XdTcE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P50454 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P50402 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P46977 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P46940 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P46782 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551|ensembl:ENSP00000470114|ensembl:ENSP00000472985 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:Small ribosomal subunit protein uS7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001000.2|rcsb pdb:6OLZ|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Z6M|rcsb pdb:6XA1|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6Y0G|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:5FLX|rcsb pdb:6OLG|rcsb pdb:6OLI|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|ensembl:ENSG00000083845(gene)|ensembl:ENST00000196551(transcript)|ensembl:ENST00000596046(transcript)|ensembl:ENST00000601521(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5AJ0|reactome:R-HSA-72702 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P46087 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356811|uniprotkb:A1A4Z3|uniprotkb:Q0P5S5|uniprotkb:Q58F30|uniprotkb:B3KPD6|uniprotkb:Q05BA7|uniprotkb:Q3KQS4|ensembl:ENSP00000313272|ensembl:ENSP00000444437 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:nop2_human(display_long)|uniprotkb:NOP2(gene name)|psi-mi:NOP2(display_short)|uniprotkb:NSUN1(gene name synonym)|uniprotkb:Proliferating-cell nucleolar antigen p120(gene name synonym)|uniprotkb:Proliferation-associated nucleolar protein p120(gene name synonym)|uniprotkb:NOL1(gene name synonym)|uniprotkb:Nucleolar protein 2 homolog(gene name synonym)|uniprotkb:Nucleolar protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001028886.1|refseq:NP_006161.2|refseq:NP_001245237.1|refseq:NP_001245238.1|refseq:NP_001245239.1|refseq:XP_005253748.1|ensembl:ENSG00000111641(gene)|ensembl:ENST00000322166(transcript)|ensembl:ENST00000537442(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR011023(Nop2p)|interpro:IPR012586(P120R)|interpro:IPR018314|interpro:IPR023267|interpro:IPR023273|interpro:IPR029063|interpro:IPR031341|mint:P46087|reactome:R-HSA-6790901|reactome:R-HSA-8869496 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:CvYaCDv8N8OvS0lPFy8jFEFaOTA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P43307 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-714168|uniprotkb:A8K685|uniprotkb:Q9TNQ8|uniprotkb:Q53GX2|uniprotkb:Q53H19|uniprotkb:Q5TAM3|uniprotkb:Q6IB43|uniprotkb:Q8NBH9|uniprotkb:Q96IA2|uniprotkb:Q9UN49|ensembl:ENSP00000244763 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ssra_human(display_long)|uniprotkb:Signal sequence receptor subunit alpha(gene name synonym)|uniprotkb:SSR1(gene name)|psi-mi:SSR1(display_short)|uniprotkb:TRAPA(gene name synonym)|uniprotkb:PSEC0262(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003135.2|ensembl:ENSG00000124783(gene)|ensembl:ENST00000244763(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005595("Translocon-associated protein (TRAP), alpha subunit")|mint:P43307|reactome:R-HSA-1799339|reactome:R-HSA-381038|refseq:NP_001278937.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:OhI1z1wbH8LEZaiv+OLChzMvT+A9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P42766 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P42677 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P39656 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P38117 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1056543|uniprotkb:Q6IBH7|uniprotkb:Q71RF6|uniprotkb:Q9Y3S7|uniprotkb:B3KNY2|uniprotkb:A8K766|ensembl:ENSP00000311930 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:etfb_human(display_long)|uniprotkb:ETFB(gene name)|psi-mi:ETFB(display_short)|uniprotkb:FP585(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001014763.1|refseq:NP_001976.1|dip:DIP-6162N|ensembl:ENSG00000105379(gene)|ensembl:ENST00000309244(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|interpro:IPR000049(Electron transfer flavoprotein, beta-subunit, core)|interpro:IPR012255(Electron transfer flavoprotein, beta subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR033948|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105|reactome:R-HSA-8876725 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Fip+C+sJJhYoSZXwU/FZvabPAEY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P36578 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-348313|ensembl:ENSP00000311430|uniprotkb:P39029|uniprotkb:Q4VBR0|uniprotkb:Q969Z9|uniprotkb:A8K502 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl4_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:RPL1(gene name synonym)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000174444(gene)|ensembl:ENST00000307961(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR025755|mint:P36578|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|interpro:IPR023574|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OM0|refseq:NP_000959.2|dip:DIP-27559N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:34il/jyrW0Dqj0eA8GBFgUk05XU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P32969 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358122|ensembl:ENSP00000346022|ensembl:ENSP00000400467|ensembl:ENSP00000494697 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl9_human(display_long)|uniprotkb:RPL9(gene name)|psi-mi:RPL9(display_short)|uniprotkb:RPL9P7(gene name)|psi-mi:RPL9P7(display_short)|uniprotkb:RPL9P8(gene name)|psi-mi:RPL9P8(display_short)|uniprotkb:RPL9P9(gene name)|psi-mi:RPL9P9(display_short)|uniprotkb:Large ribosomal subunit protein uL6(gene name synonym)|uniprotkb:OK/SW-cl.103(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000652.2|refseq:NP_001020092.1|ensembl:ENSG00000163682(gene)|ensembl:ENST00000295955(transcript)|ensembl:ENST00000449470(transcript)|ensembl:ENST00000645496(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|mint:P32969|rcsb pdb:2CQL|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:v0thFydYo0aEqBblJoqQX8b7JCA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P31040 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P30050 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:TNPEtl60cILofaPzUznvZiw6D7E9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P29692 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358607|uniprotkb:Q969J1|uniprotkb:D3DWK3|intact:EBI-748782|uniprotkb:Q96I38|ensembl:ENSP00000317399|ensembl:ENSP00000378551|ensembl:ENSP00000388261|ensembl:ENSP00000433412|ensembl:ENSP00000433611|ensembl:ENSP00000434448|ensembl:ENSP00000434872|ensembl:ENSP00000436542|ensembl:ENSP00000436933|ensembl:ENSP00000478340|ensembl:ENSP00000479653|ensembl:ENSP00000483527|ensembl:ENSP00000487680|intact:EBI-11048966|uniprotkb:Q4VBZ6|uniprotkb:B4DDU4|uniprotkb:E9PBQ9 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ef1d_human(display_long)|uniprotkb:EEF1D(gene name)|psi-mi:EEF1D(display_short)|uniprotkb:EF1D(gene name synonym)|uniprotkb:Antigen NY-CO-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001123528.1|refseq:NP_001123527.1|refseq:NP_001123529.1|refseq:NP_001951.2|refseq:XP_011515207.1|refseq:XP_011515208.1|ensembl:ENST00000419152(transcript)|ensembl:ENST00000529272(transcript)|ensembl:ENST00000530191(transcript)|ensembl:ENST00000530445(transcript)|ensembl:ENST00000531218(transcript)|ensembl:ENST00000533494(transcript)|ensembl:ENST00000534380(transcript)|ensembl:ENST00000614575(transcript)|ensembl:ENST00000615067(transcript)|ensembl:ENST00000615698(transcript)|ensembl:ENST00000632587(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0009299"(mRNA transcription)|go:"GO:0010941"(regulation of cell death)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|mint:P29692|rcsb pdb:2MVM|rcsb pdb:2MVN|rcsb pdb:2N51|rcsb pdb:5JPO|reactome:R-HSA-156842|ensembl:ENSG00000104529(gene)|ensembl:ENSG00000273594(gene)|ensembl:ENST00000317198(transcript)|ensembl:ENST00000395119(transcript)|refseq:NP_001304672.1|refseq:NP_001182132.1|refseq:NP_001276879.1|refseq:XP_006716585.1|refseq:XP_006716586.1|refseq:XP_006716587.1|refseq:XP_006716588.1|refseq:XP_005250880.1|refseq:NP_001317575.1|refseq:XP_016868659.1|refseq:NP_001123525.2|refseq:NP_115754.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:9Mzpfofeg2W/GQ/JfjFxcCFJnKg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P27695 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P26373 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356849|uniprotkb:Q3KQT8|uniprotkb:Q9BPX0|uniprotkb:Q567Q8|uniprotkb:B4DLX3|uniprotkb:F5H1S2|ensembl:ENSP00000307889|ensembl:ENSP00000376811|ensembl:ENSP00000455009 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl13_human(display_long)|uniprotkb:RPL13(gene name)|psi-mi:RPL13(display_short)|uniprotkb:BBC1(gene name synonym)|uniprotkb:Breast basic conserved protein 1(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL13(gene name synonym)|uniprotkb:OK/SW-cl.46(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000968.2|refseq:NP_150254.1|refseq:NP_001230059.1|refseq:NP_001230060.1|ensembl:ENSG00000167526(gene)|ensembl:ENST00000311528(transcript)|ensembl:ENST00000393099(transcript)|ensembl:ENST00000567815(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0060348"(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P26373|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-192823 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:2SZ+AEe41Ystwj9t9I0Z1cZ5GQ49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P25205 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P23588 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P23528 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629|ensembl:ENSP00000432660 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005498.1|ensembl:ENSG00000172757(gene)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|ensembl:ENST00000308162(transcript)|ensembl:ENST00000525451(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009615"(response to virus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0031258"(lamellipodium membrane)|dip:DIP-33000N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P20930 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1058782|ensembl:ENSP00000357789|uniprotkb:Q01720|uniprotkb:Q5T583|uniprotkb:Q9UC71 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:fila_human(display_long)|uniprotkb:FLG(gene name)|psi-mi:FLG(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENST00000368799(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007275"(multicellular organism development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0061436"(establishment of skin barrier)|ensembl:ENSG00000143631(gene)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003303(Filaggrin)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR034325|rcsb pdb:4PCW|reactome:R-HSA-6809371|go:"GO:0062023"(collagen-containing extracellular matrix)|refseq:NP_002007.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:RXgRbd4W6ydxD/M1cEUUzUFGuJ09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P20674 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-715032|uniprotkb:P30045|intact:EBI-1043629|uniprotkb:Q8TB65|ensembl:ENSP00000317780|ensembl:ENSP00000456386 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cox5a_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)|uniprotkb:COX5A(gene name)|psi-mi:COX5A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004246.2|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P20674|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178741(gene)|ensembl:ENST00000322347(transcript)|ensembl:ENST00000564811(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:dWvZKYawyJQwN29Mhkm44DXXqhg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P20042 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-711977|ensembl:ENSP00000364119|uniprotkb:Q9BVU0|uniprotkb:Q9UJE4 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:if2b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit beta(gene name synonym)|uniprotkb:EIF2S2(gene name)|psi-mi:EIF2S2(display_short)|uniprotkb:EIF2B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000125977(gene)|ensembl:ENST00000374980(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002176"(male germ cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008584"(male gonad development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:P20042|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_003899.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:64ZkCKZ5jRT6MEm9RK4AynY2ga49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P18077 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P15880 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P10599 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|uniprotkb:Q9UDG5|intact:EBI-1042712|ensembl:ENSP00000363641 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|ensembl:ENSG00000136810(gene)|ensembl:ENST00000374517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:1W1C|rcsb pdb:1W1E|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P09923 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1052631|uniprotkb:Q53S80|uniprotkb:Q9UBV5|uniprotkb:Q9UCL2|uniprotkb:B2R7Y4|ensembl:ENSP00000295463 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ppbi_human(display_long)|uniprotkb:ALPI(gene name)|psi-mi:ALPI(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001622.2|ensembl:ENSG00000163295(gene)|ensembl:ENST00000295463(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002020"(protease binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|reactome:R-HSA-1483166|reactome:R-HSA-163125|reactome:R-HSA-8935690 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:RVz6SrTgIp87b+FLyMYQuoQDsI49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08579 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1053651|uniprotkb:Q9UJD4|uniprotkb:B2R7J3|uniprotkb:D3DW21|ensembl:ENSP00000246071|ensembl:ENSP00000367178 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ru2b_human(display_long)|uniprotkb:SNRPB2(gene name)|psi-mi:SNRPB2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003083.1|refseq:NP_937863.1|ensembl:ENSG00000125870(gene)|ensembl:ENST00000246071(transcript)|ensembl:ENST00000377943(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070990"(snRNP binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034562|interpro:IPR034564|interpro:IPR035979|mint:P08579|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:AzDL3wfFG4HmOfTs8NJL6bWjgrc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08133 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352541|uniprotkb:B7Z8A7|uniprotkb:E9PGK1|uniprotkb:Q6ZT79|uniprotkb:D3DQH4|ensembl:ENSP00000346550 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:anxa6_human(display_long)|uniprotkb:ANXA6(gene name)|psi-mi:ANXA6(display_short)|uniprotkb:ANX6(gene name synonym)|uniprotkb:Annexin-6(gene name synonym)|uniprotkb:Annexin VI(gene name synonym)|uniprotkb:Lipocortin VI(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Protein III(gene name synonym)|uniprotkb:Chromobindin-20(gene name synonym)|uniprotkb:67 kDa calelectrin(gene name synonym)|uniprotkb:Calphobindin-II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001146.2|refseq:NP_001180473.1|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0008289"(lipid binding)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051283"(negative regulation of sequestering of calcium ion)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENSG00000197043(gene)|ensembl:ENST00000354546(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003418"(growth plate cartilage chondrocyte differentiation)|interpro:IPR001464(Annexin)|interpro:IPR002393(Annexin, type VI)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1M9I|reactome:R-HSA-445355 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:+1oKdgl2a0haedrMSJ8au35MF8c9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P07339 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P06733 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P04844 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001129243.1|refseq:NP_002942.2|ensembl:ENSG00000118705(gene)|ensembl:ENST00000237530(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007568"(aging)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042493"|go:"GO:0043022"(ribosome binding)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001311234.1|refseq:NP_001311235.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P04075 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P04040 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001743.1|ensembl:ENSG00000121691(gene)|ensembl:ENST00000241052(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P02788 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O75531 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1055977|uniprotkb:O60558|uniprotkb:Q6FGG7|ensembl:ENSP00000310275|ensembl:ENSP00000416128|ensembl:ENSP00000432867|ensembl:ENSP00000433760 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:baf_human(display_long)|uniprotkb:BANF1(gene name)|psi-mi:BANF1(display_short)|uniprotkb:BAF(gene name synonym)|uniprotkb:BCRG1(gene name synonym)|uniprotkb:Breakpoint cluster region protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001137457.1|refseq:NP_003851.1|ensembl:ENST00000445560(transcript)|ensembl:ENST00000527348(transcript)|ensembl:ENST00000533166(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0097726"(LEM domain binding)|interpro:IPR004122(Barrier to autointegration factor, BAF)|interpro:IPR036617|mint:O75531|rcsb pdb:1CI4|rcsb pdb:1QCK|rcsb pdb:2BZF|rcsb pdb:2EZX|rcsb pdb:2EZY|rcsb pdb:2EZZ|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:6UNT|rcsb pdb:6URE|rcsb pdb:6URJ|rcsb pdb:6URK|rcsb pdb:6URL|rcsb pdb:6URN|rcsb pdb:6URR|rcsb pdb:6URZ|rcsb pdb:6US0|rcsb pdb:6US1|rcsb pdb:6US7|rcsb pdb:6USB|rcsb pdb:6USD|rcsb pdb:6USI|rcsb pdb:7NDY|ensembl:ENSG00000175334(gene)|ensembl:ENST00000312175(transcript)|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|reactome:R-HSA-2980766|reactome:R-HSA-2995383|refseq:XP_016874003.1|refseq:XP_016874004.1|dip:DIP-50395N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:JSfPqQhIXIFEXNQn1+I8v5zG+Hw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O75525 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O75475 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1801773|uniprotkb:O00256|uniprotkb:O95368|uniprotkb:Q6P391|uniprotkb:Q86YB9|uniprotkb:Q9NZI3|uniprotkb:Q9UER6|uniprotkb:D3DRI9|ensembl:ENSP00000370109|ensembl:ENSP00000370114 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:psip1_human(display_long)|uniprotkb:PSIP1(gene name)|psi-mi:PSIP1(display_short)|uniprotkb:DFS70(gene name synonym)|uniprotkb:LEDGF(gene name synonym)|uniprotkb:PSIP2(gene name synonym)|uniprotkb:Lens epithelium-derived growth factor(gene name synonym)|uniprotkb:Transcriptional coactivator p75/p52(gene name synonym)|uniprotkb:Dense fine speckles 70 kDa protein(gene name synonym)|uniprotkb:CLL-associated antigen KW-7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001304827.1|refseq:NP_001304829.1|refseq:NP_001121689.1|refseq:NP_066967.3|refseq:NP_150091.2|dip:DIP-46656N|ensembl:ENSG00000164985(gene)|ensembl:ENST00000380733(transcript)|ensembl:ENST00000380738(transcript)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009408"(response to heat)|go:"GO:0034399"(nuclear periphery)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000313(PWWP)|interpro:IPR021567|interpro:IPR035441|interpro:IPR035496|interpro:IPR036218|mint:O75475|rcsb pdb:1Z9E|rcsb pdb:2B4J|rcsb pdb:2M16|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2N3A|rcsb pdb:3F9K|rcsb pdb:3HPG|rcsb pdb:3HPH|rcsb pdb:3U88|rcsb pdb:3ZEH|rcsb pdb:4FU6|rcsb pdb:5N88|rcsb pdb:5OYM|rcsb pdb:5YI9|rcsb pdb:6EMO|rcsb pdb:6EMP|rcsb pdb:6EMQ|rcsb pdb:6EMR|rcsb pdb:6S01|rcsb pdb:6TRJ|rcsb pdb:6TVM|rcsb pdb:6Z2Y|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:MRtOw4kH/FxVku25dO5RQiNTjDA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O75396 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1058865|ensembl:ENSP00000463393|uniprotkb:A8K1G0 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000265808(gene)|ensembl:ENST00000578049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|refseq:NP_004883.3|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|reactome:R-HSA-1236974|dip:DIP-50458N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:DRKtD169T9eYZ2kFufLapidvcKs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O75390 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-487493|ensembl:ENSP00000342056|uniprotkb:Q71UT9|uniprotkb:Q7KZH0|uniprotkb:Q96FZ8|uniprotkb:Q9BWN8 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cisy_human(display_long)|uniprotkb:CS(gene name)|psi-mi:CS(display_short)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0006101"(citrate metabolic process)|refseq:NP_004068.2|ensembl:ENSG00000062485(gene)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000351328(transcript)|rcsb pdb:5UZQ|rcsb pdb:5UZR|reactome:R-HSA-1268020|reactome:R-HSA-71403|go:"GO:0070062"(extracellular exosome)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|rcsb pdb:5UZP - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:XKpnEsGOlGRNIAXMk4tTBH2okzo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O60884 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O15523 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2462220|uniprotkb:Q8IYV7|uniprotkb:B4DK29|uniprotkb:B4DXX7|ensembl:ENSP00000336725|ensembl:ENSP00000353284 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ddx3y_human(display_long)|uniprotkb:DDX3Y(gene name)|psi-mi:DDX3Y(display_short)|uniprotkb:DBY(gene name synonym)|uniprotkb:DEAD box protein 3, Y-chromosomal(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001116137.1|refseq:NP_004651.2|refseq:NP_001289481.1|ensembl:ENSG00000067048(gene)|ensembl:ENST00000336079(transcript)|ensembl:ENST00000360160(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007276"(gamete generation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O15523 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:dYhBr9Igq5eMq9U8g+c30nfdaKo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O15042 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-310697|uniprotkb:A0PJ60|uniprotkb:Q0D2M1|uniprotkb:Q2NKQ7|uniprotkb:Q9BR70|intact:EBI-2555384|ensembl:ENSP00000418563 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sr140_human(display_long)|uniprotkb:KIAA0332(gene name synonym)|uniprotkb:U2SURP(gene name)|psi-mi:U2SURP(display_short)|uniprotkb:140 kDa Ser/Arg-rich domain protein(gene name synonym)|uniprotkb:SR140(gene name synonym)|uniprotkb:U2-associated protein SR140(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001073884.1|refseq:NP_001307148.1|refseq:NP_001307149.1|refseq:NP_001307151.1|ensembl:ENSG00000163714(gene)|ensembl:ENST00000473835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR035009|interpro:IPR035967|interpro:IPR035979|reactome:R-HSA-72163|refseq:XP_016861527.1|refseq:XP_016861528.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:STKTFD8Cu0GQMj+HSpn3qgIEw4c9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O14983 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-359186|uniprotkb:O14984|uniprotkb:A8K5J9|ensembl:ENSP00000349595|uniprotkb:B3KY17 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:at2a1_human(display_long)|uniprotkb:ATP2A1(gene name)|psi-mi:ATP2A1(display_short)|uniprotkb:Calcium pump 1(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004311.1|refseq:NP_775293.1|ensembl:ENSG00000196296(gene)|ensembl:ENST00000357084(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0031673"(H zone)|go:"GO:0031674"(I band)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034704"(calcium channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902082"(positive regulation of calcium ion import into sarcoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O14983|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001273004.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:3cHH/E8HuaFCoTd7hO/0SFTnqtg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:B2RPK0 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-13943428 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hgb1a_human(display_long)|uniprotkb:HMGB1P1(gene name)|psi-mi:HMGB1P1(display_short)|uniprotkb:HMG1L1(gene name synonym)|uniprotkb:HMGB1L1(gene name synonym)|uniprotkb:High mobility group protein B1 pseudogene 1(gene name synonym)|uniprotkb:Putative high mobility group protein 1-like 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|mint:B2RPK0|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR031076|interpro:IPR036910 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ppgkTWseGeSKMW8zLWwg1AmkhlY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9BUL8 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q86YV9 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-721349|uniprotkb:Q9H685|uniprotkb:Q5VV69|ensembl:ENSP00000299238 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hps6_human(display_long)|uniprotkb:Ruby-eye protein homolog(gene name synonym)|uniprotkb:HPS6(gene name)|psi-mi:HPS6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_079023.2|ensembl:ENSG00000166189(gene)|ensembl:ENST00000299238(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006996"(organelle organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031084"(BLOC-2 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR017218(BLOC-2 complex, Hps6 subunit) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:I+W2a3A5D9XIWztpoMXFxQod8/M9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q05707 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2528599|uniprotkb:B2RU07|uniprotkb:O00260|uniprotkb:O00261|uniprotkb:O00262|uniprotkb:Q05708|uniprotkb:Q5XJ18|uniprotkb:Q96C67|uniprotkb:Q9UDF6|ensembl:ENSP00000297848 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:coea1_human(display_long)|uniprotkb:COL14A1(gene name)|psi-mi:COL14A1(display_short)|uniprotkb:UND(gene name synonym)|uniprotkb:Undulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:XP_016869298.1|refseq:NP_066933.1|refseq:XP_005251116.1|refseq:XP_006716714.1|ensembl:ENSG00000187955(gene)|ensembl:ENST00000297848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005596"(collagen type XIV trimer)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001791(Laminin G)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036465|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8948216 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:8eQ55YOi3IK4OWPI57s3ak2q4bg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P35030 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P32119 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P0C0L4 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000388662|ensembl:ENSP00000396688|ensembl:ENSP00000372815 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_009224.2|refseq:NP_001002029.3|refseq:NP_001239133.1|ensembl:ENSG00000206340(gene)|ensembl:ENSG00000227746(gene)|ensembl:ENSG00000244731(gene)|ensembl:ENST00000383325(transcript)|ensembl:ENST00000421274(transcript)|ensembl:ENST00000428956(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|rcsb pdb:1HZF|rcsb pdb:4FXG|rcsb pdb:4FXK|rcsb pdb:4XAM|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P01859 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1044662|uniprotkb:A6NE66|ensembl:ENSP00000374987|ensembl:ENSP00000480351 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ighg2_human(display_long)|uniprotkb:IGHG2(gene name)|psi-mi:IGHG2(display_short)|uniprotkb:Ig gamma-2 chain C region(gene name synonym)|uniprotkb:Ig gamma-2 chain C region DOT(gene name synonym)|uniprotkb:Ig gamma-2 chain C region TIL(gene name synonym)|uniprotkb:Ig gamma-2 chain C region ZIE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|rcsb pdb:4L4J|ensembl:ENSG00000211893(gene)|ensembl:ENSG00000274497(gene)|ensembl:ENST00000390545(transcript)|ensembl:ENST00000621803(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2QSC|rcsb pdb:4HAF|rcsb pdb:4HAG - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:EZkOg27Ga0FblVGpeMMQzW0s/xo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P01594 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-15853604|ensembl:ENSP00000420020|ensembl:ENSP00000487732|uniprotkb:A0A087WZH9|uniprotkb:P01603 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:kv133_human(display_long)|uniprotkb:IGKV1-33(gene name)|psi-mi:IGKV1-33(display_short)|uniprotkb:Ig kappa chain V-I region AU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Ka(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000242076(gene)|ensembl:ENSG00000282811(gene)|ensembl:ENST00000473726(transcript)|ensembl:ENST00000632835(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B0W|rcsb pdb:1JV5|rcsb pdb:1QP1|rcsb pdb:2Q20|rcsb pdb:3CDC|rcsb pdb:3CDF|rcsb pdb:3CDY|rcsb pdb:4K07|rcsb pdb:7CZQ|rcsb pdb:7CZU|rcsb pdb:7CZV|reactome:R-HSA-166663|reactome:R-HSA-173623|go:"GO:0005615"(extracellular space)|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|dip:DIP-58572N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:+8FNYvbRPCc9GI9G4Tf+BdsBnd49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9Y2W1 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634|ensembl:ENSP00000433825 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005110.2|ensembl:ENSG00000054118(gene)|ensembl:ENST00000354618(transcript)|ensembl:ENST00000469141(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026667|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|refseq:NP_001308400.1|refseq:NP_001308402.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15366 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15365 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q14103 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P84103 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-372557|uniprotkb:P23152|uniprotkb:O08831|uniprotkb:B4E241|intact:EBI-11020748|uniprotkb:Q5R3K0|ensembl:ENSP00000362820|ensembl:ENSP00000482833 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:srsf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP20(gene name synonym)|uniprotkb:SRSF3(gene name)|psi-mi:SRSF3(display_short)|uniprotkb:SRP20(gene name synonym)|uniprotkb:SFRS3(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003008.1|ensembl:ENSG00000112081(gene)|ensembl:ENST00000373715(transcript)|ensembl:ENST00000620941(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0043274"(phospholipase binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P84103|rcsb pdb:2I2Y|rcsb pdb:2I38|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|dip:DIP-32961N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:BcfyCj2cNNTH1igANKpvh4IHDVU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62937 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-437708|uniprotkb:P05092|uniprotkb:Q3KQW3|uniprotkb:Q6IBU5|uniprotkb:Q96IX3|uniprotkb:Q9BRU4|uniprotkb:Q9BTY9|uniprotkb:Q9UC61|uniprotkb:Q567Q0|ensembl:ENSP00000419425|uniprotkb:A8K220 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ppia_human(display_long)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:PPIA(gene name)|psi-mi:PPIA(display_short)|uniprotkb:CYPA(gene name synonym)|uniprotkb:Rotamase A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_066953.1|interpro:IPR029000|mint:P62937|rcsb pdb:1AK4|rcsb pdb:1AWQ|rcsb pdb:1AWR|rcsb pdb:1AWS|rcsb pdb:1AWT|rcsb pdb:1AWU|rcsb pdb:1AWV|rcsb pdb:1BCK|rcsb pdb:1CWA|rcsb pdb:1CWB|rcsb pdb:1CWC|rcsb pdb:1CWF|rcsb pdb:1CWH|rcsb pdb:1CWI|rcsb pdb:1CWJ|rcsb pdb:1CWK|rcsb pdb:1CWL|rcsb pdb:1CWM|interpro:IPR024936|rcsb pdb:1CWO|rcsb pdb:1FGL|rcsb pdb:2N0T|rcsb pdb:2RMA|rcsb pdb:1M63|rcsb pdb:2RMB|rcsb pdb:2X25|rcsb pdb:2X2A|rcsb pdb:2X2C|rcsb pdb:2X2D|rcsb pdb:1M9C|rcsb pdb:1M9D|rcsb pdb:1M9E|rcsb pdb:2XGY|rcsb pdb:3CYH|rcsb pdb:3CYS|rcsb pdb:3K0M|rcsb pdb:3K0N|rcsb pdb:3K0O|rcsb pdb:3K0P|rcsb pdb:3K0Q|rcsb pdb:3K0R|rcsb pdb:3ODI|rcsb pdb:3ODL|rcsb pdb:1M9F|rcsb pdb:3RDD|rcsb pdb:1M9X|rcsb pdb:1M9Y|rcsb pdb:4CYH|rcsb pdb:4IPZ|rcsb pdb:4N1M|rcsb pdb:4N1N|rcsb pdb:1MF8|rcsb pdb:4N1O|rcsb pdb:4N1P|rcsb pdb:4N1Q|rcsb pdb:1MIK|rcsb pdb:1NMK|rcsb pdb:1OCA|rcsb pdb:1RMH|rcsb pdb:1VBS|rcsb pdb:1VBT|rcsb pdb:1W8L|rcsb pdb:1W8M|rcsb pdb:1W8V|rcsb pdb:1YND|rcsb pdb:1ZKF|rcsb pdb:2ALF|rcsb pdb:2CPL|rcsb pdb:2CYH|rcsb pdb:2MS4|rcsb pdb:2MZU|rcsb pdb:4N1R|rcsb pdb:4N1S|rcsb pdb:4YUG|rcsb pdb:4YUH|refseq:NP_001287910.1|reactome:R-HSA-210991|reactome:R-HSA-6798695|reactome:R-HSA-8950505|reactome:R-HSA-2025928|ensembl:ENSG00000196262(gene)|ensembl:ENST00000468812(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031982"(vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046790"(virion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|go:"GO:0005178"(integrin binding)|rcsb pdb:4YUI|rcsb pdb:4YUJ|rcsb pdb:4YUK|rcsb pdb:4YUL|rcsb pdb:4YUM|rcsb pdb:4YUN|rcsb pdb:4YUO|rcsb pdb:4YUP|rcsb pdb:5CYH|rcsb pdb:5F66|rcsb pdb:5FJB|rcsb pdb:5KUL|rcsb pdb:5KUN|rcsb pdb:5KUO|rcsb pdb:5KUQ|rcsb pdb:5KUR|rcsb pdb:5KUS|rcsb pdb:5KUU|rcsb pdb:5KUV|rcsb pdb:5KUW|rcsb pdb:5KUZ|rcsb pdb:5KV0|rcsb pdb:5KV1|rcsb pdb:5KV2|rcsb pdb:5KV3|rcsb pdb:5KV4|rcsb pdb:5KV5|rcsb pdb:5KV6|rcsb pdb:5KV7|rcsb pdb:5LUD|rcsb pdb:5NOQ|rcsb pdb:5NOR|rcsb pdb:5NOT|rcsb pdb:5NOU|rcsb pdb:5NOV|rcsb pdb:5NOW|rcsb pdb:5NOX|rcsb pdb:5NOY|rcsb pdb:5NOZ|rcsb pdb:5T9U|rcsb pdb:5T9W|rcsb pdb:5T9Z|rcsb pdb:5TA2|rcsb pdb:5TA4|rcsb pdb:5WC7|rcsb pdb:6BTA|rcsb pdb:6GJI|rcsb pdb:6GJJ|rcsb pdb:6GJL|rcsb pdb:6GJM|rcsb pdb:6GJN|rcsb pdb:6GJP|rcsb pdb:6GJR|rcsb pdb:6GJY|rcsb pdb:6GS6|rcsb pdb:6I42|rcsb pdb:6U5C|rcsb pdb:6U5D|rcsb pdb:6U5E|rcsb pdb:6U5G|rcsb pdb:6X3R|rcsb pdb:6X3Y|rcsb pdb:5NOS|rcsb pdb:6X4N|rcsb pdb:6X4O|rcsb pdb:6X4P|rcsb pdb:6X4Q|rcsb pdb:6Y9V|rcsb pdb:6Y9W|rcsb pdb:6Y9X|rcsb pdb:6Y9Y|rcsb pdb:6Y9Z|rcsb pdb:6ZDJ|rcsb pdb:7ABT|reactome:R-HSA-114608|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-173107|rcsb pdb:6X4M|reactome:R-HSA-175474|reactome:R-HSA-180689|dip:DIP-6080N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:dr4EVxcO+sqTPBqsQcydRn+rHoo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P01602 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2371313|uniprotkb:A0A075B6S8|intact:EBI-4286966|uniprotkb:P01596|uniprotkb:P01598|uniprotkb:P01604|ensembl:ENSP00000420436|ensembl:ENSP00000488639 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:kv105_human(display_long)|uniprotkb:IGKV1-5(gene name)|psi-mi:IGKV1-5(display_short)|uniprotkb:Ig kappa chain V-I region HK102(gene name synonym)|uniprotkb:Ig kappa chain V-I region CAR(gene name synonym)|uniprotkb:Ig kappa chain V-I region EU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Kue(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000243466(gene)|ensembl:ENSG00000282801(gene)|ensembl:ENST00000496168(transcript)|ensembl:ENST00000632205(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:WKovn0mvryvDbJqn6iNbiFvN+rw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9P0L0 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9BQG0 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q96PK6 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q8NBS9 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:bz5VVWMPFLTRKwph60UFASjsFN49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q75N03 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|intact:EBI-28973894|ensembl:ENSP00000401277|uniprotkb:B7ZM03 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENST00000222597|ensembl:ENSP00000222597|ensembl:ENSP00000401277|ensembl:ENSG00000105879(gene)|ensembl:ENST00000440859(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|refseq:NP_079090.2|refseq:NP_001271220.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q5D862 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2952722|ensembl:ENSP00000373370|uniprotkb:Q9H4U1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:fila2_human(display_long)|uniprotkb:FLG2(gene name)|psi-mi:FLG2(display_short)|uniprotkb:IFPS(gene name synonym)|uniprotkb:Intermediate filament-associated and psoriasis-susceptibility protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSP00000373370|ensembl:ENSG00000143520(gene)|ensembl:ENST00000388718(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003303(Filaggrin)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR034325|mint:Q5D862|reactome:R-HSA-6798695|go:"GO:0036457"(keratohyalin granule)|refseq:NP_001014364.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:b0VRX4uLQtUVeodRvtwEWgfmzZc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15393 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13813 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13263 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13148 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q12906 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q12905 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q01844 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q01130 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q01082 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P83731 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62851 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353054|ensembl:ENSP00000435096|ensembl:ENSP00000486392|uniprotkb:P25111|uniprotkb:B2R4M7 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs25_human(display_long)|uniprotkb:RPS25(gene name)|psi-mi:RPS25(display_short)|uniprotkb:Small ribosomal subunit protein eS25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000118181(gene)|ensembl:ENSG00000280831(gene)|ensembl:ENST00000527673(transcript)|ensembl:ENST00000628770(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004977(Ribosomal protein S25)|interpro:IPR036388|mint:P62851|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y0G|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:6ZXD|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|rcsb pdb:6ZXE|reactome:R-HSA-9010553|reactome:R-HSA-9633012|rcsb pdb:6ZXF|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|refseq:NP_001019.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62424 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62318 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-372789|uniprotkb:P43331|uniprotkb:B5BU13|uniprotkb:B4DJP7|ensembl:ENSP00000215829|intact:EBI-10981086 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:smd3_human(display_long)|uniprotkb:SNRPD3(gene name)|psi-mi:SNRPD3(display_short)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004166.1|refseq:NP_001265585.1|ensembl:ENSG00000100028(gene)|ensembl:ENST00000215829(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|mint:P62318|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|rcsb pdb:7ABG|rcsb pdb:3VRI|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:3PGW|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|dip:DIP-31216N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:WkrSZVfVmSQrJYfy7mwp48xjsVA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62263 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352783|ensembl:ENSP00000311028|ensembl:ENSP00000385425|uniprotkb:P06366|uniprotkb:Q5BJI0|uniprotkb:B2R5G5|uniprotkb:D3DQG5|ensembl:ENSP00000385958|ensembl:ENSP00000428509 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs14_human(display_long)|uniprotkb:RPS14(gene name)|psi-mi:RPS14(display_short)|uniprotkb:Small ribosomal subunit protein uS11(gene name synonym)|uniprotkb:PRO2640(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000164587(gene)|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001020242.1|refseq:NP_005608.1|refseq:NP_001020241.1|ensembl:ENST00000312037(transcript)|ensembl:ENST00000401695(transcript)|ensembl:ENST00000407193(transcript)|ensembl:ENST00000521466(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P62263|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ee3bJ5JYFaZXyCCRG9Wooopyz2o9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62241 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351811|uniprotkb:Q6IRL7|uniprotkb:P09058|ensembl:ENSP00000379888 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs8_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:Small ribosomal subunit protein eS8(gene name synonym)|uniprotkb:OK/SW-cl.83(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001003.1|ensembl:ENSG00000142937(gene)|ensembl:ENST00000396651(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62241|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:6G5H|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975957|reactome:R-HSA-975956 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P61604 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P61353 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P60842 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P53675 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358826|uniprotkb:Q14017|uniprotkb:Q15808|uniprotkb:Q15809|uniprotkb:B7Z7U5|ensembl:ENSP00000441158 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:clh2_human(display_long)|uniprotkb:CLTCL1(gene name)|psi-mi:CLTCL1(display_short)|uniprotkb:CLH22(gene name synonym)|uniprotkb:CLTCL(gene name synonym)|uniprotkb:CLTD(gene name synonym)|uniprotkb:Clathrin heavy chain on chromosome 22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001826.3|refseq:NP_009029.3|ensembl:ENSG00000070371(gene)|ensembl:ENST00000427926(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030135"(coated vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071439"(clathrin complex)|go:"GO:0097443"(sorting endosome)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-3928665|reactome:R-HSA-8856825|reactome:R-HSA-8856828 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:s+bmcNpUy0+PyN1d5eXCAvHBqus9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P45880 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354022|ensembl:ENSP00000361686|ensembl:ENSP00000443092|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000165637(gene)|ensembl:ENST00000332211(transcript)|ensembl:ENST00000543351(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|refseq:NP_001311017.1|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P45880|reactome:R-HSA-5689880|reactome:R-HSA-8949215 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:seQxCd19Z2HmpXcwb48osAuuafA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P42167 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-455283|uniprotkb:Q14861|ensembl:ENSP00000450627|uniprotkb:A2T926 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:lap2b_human(display_long)|uniprotkb:Thymopoietin-related peptide isoforms beta/gamma(gene name synonym)|uniprotkb:Thymopoietin, isoforms beta/gamma(gene name synonym)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001294904.1|refseq:NP_001027454.1|refseq:NP_001027455.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000556029(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:P42167|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|dip:DIP-43686N|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:S2mYrSugx0Ms4vhw/vYYH/SthOw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P35659 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P35268 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P31944 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P30048 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P27635 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P27348 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P26641 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P26368 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-742339|uniprotkb:Q96HC5|intact:EBI-946034|ensembl:ENSP00000307863 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:u2af2_human(display_long)|uniprotkb:U2AF2(gene name)|psi-mi:U2AF2(display_short)|uniprotkb:U2AF65(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0005634"(nucleus)|refseq:NP_001012496.1|refseq:NP_009210.1|ensembl:ENSG00000063244(gene)|ensembl:ENST00000308924(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|rcsb pdb:2HZC|rcsb pdb:2M0G|rcsb pdb:2U2F|rcsb pdb:2YH0|rcsb pdb:2YH1|rcsb pdb:3VAF|rcsb pdb:3VAG|rcsb pdb:3VAH|rcsb pdb:3VAI|rcsb pdb:3VAJ|rcsb pdb:3VAK|rcsb pdb:3VAL|rcsb pdb:3VAM|rcsb pdb:4FXW|rcsb pdb:4TU7|rcsb pdb:4TU8|rcsb pdb:4TU9|rcsb pdb:5EV1|rcsb pdb:5EV2|rcsb pdb:5EV3|rcsb pdb:5EV4|rcsb pdb:5W0G|rcsb pdb:5W0H|rcsb pdb:6TR0|rcsb pdb:6XLV|rcsb pdb:6XLW|rcsb pdb:6XLX|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:2G4B|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26368|rcsb pdb:1JMT|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:1U2F|go:"GO:0005654"(nucleoplasm)|dip:DIP-2154N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:HBYwOej94CoGGN7vPbk0AnbO61Q9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P26038 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-528768|ensembl:ENSP00000353408 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:moes_human(display_long)|uniprotkb:Membrane-organizing extension spike protein(gene name synonym)|uniprotkb:MSN(gene name)|psi-mi:MSN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002435.1|ensembl:ENSG00000147065(gene)|ensembl:ENST00000360270(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001931"(uropod)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005925"(focal adhesion)|go:"GO:0031982"(vesicle)|go:"GO:0042098"(T cell proliferation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070489"(T cell aggregation)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009986"(cell surface)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0072678"(T cell migration)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000401"(regulation of lymphocyte migration)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P26038|rcsb pdb:1E5W|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016323"(basolateral plasma membrane)|rcsb pdb:1EF1|rcsb pdb:1SGH|rcsb pdb:6TXQ|go:"GO:0016324"(apical plasma membrane)|rcsb pdb:6TXS|reactome:R-HSA-437239|reactome:R-HSA-8950505|reactome:R-HSA-9662360|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-9662361|go:"GO:0019901"(protein kinase binding)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0031143"(pseudopodium)|go:"GO:0031528"(microvillus membrane)|dip:DIP-33841N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:XYzuC8VtaVyNYyZ2G5wVbxyPPww9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P21796 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P18621 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P14678 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-372458|uniprotkb:Q15490|uniprotkb:Q9UIS5|uniprotkb:Q6IB35|ensembl:ENSP00000412566 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rsmb_human(display_long)|uniprotkb:Sm protein B/B'(gene name synonym)|uniprotkb:SNRPB(gene name)|psi-mi:SNRPB(display_short)|uniprotkb:COD(gene name synonym)|uniprotkb:SNRPB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003082.1|refseq:NP_937859.1|ensembl:ENSG00000125835(gene)|ensembl:ENST00000438552(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007420"(brain development)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:1990446"(U1 snRNP binding)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN)|mint:P14678|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|dip:DIP-31239N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:zm9vJCpHG8w5iKErbOphUDCXTPk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P13639 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P13010 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P10909 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1104674|uniprotkb:B3KSE6|uniprotkb:P11380|uniprotkb:P11381|uniprotkb:Q5HYC1|uniprotkb:Q7Z5B9|uniprotkb:B2R9Q1|uniprotkb:Q2TU75|ensembl:ENSP00000315130|ensembl:ENSP00000385419|ensembl:ENSP00000429620 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:clus_human(display_long)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:Sulfated glycoprotein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0006629"(lipid metabolic process)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017038"(protein import)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000120885(gene)|ensembl:ENST00000316403(transcript)|ensembl:ENST00000405140(transcript)|ensembl:ENST00000523500(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002434"(immune complex clearance)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042583"(chromaffin granule)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0099020"(perinuclear endoplasmic reticulum lumen)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902847"(regulation of neuronal signal transduction)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1905892"(negative regulation of cellular response to thapsigargin)|go:"GO:1905895"(negative regulation of cellular response to tunicamycin)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000753(Clusterin-like)|interpro:IPR016014(Clusterin, N-terminal)|interpro:IPR016015(Clusterin, C-terminal)|interpro:IPR016016(Clusterin)|interpro:IPR033986|mint:P10909|reactome:R-HSA-114608|reactome:R-HSA-166665|reactome:R-HSA-6803157|go:"GO:0060548"(negative regulation of cell death)|reactome:R-HSA-977606|refseq:NP_001822.3|dip:DIP-37546N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:qlCJp4zYTklC3YZNQvbLmZBiz4U9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P09874 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P07237 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P05388 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P05089 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P04843 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P02751 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P00747 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P00505 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-720214|uniprotkb:Q9BWA3|uniprotkb:Q53FL3|intact:EBI-1058557|ensembl:ENSP00000245206|uniprotkb:B4DJA6|uniprotkb:E7ERW2 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:aatm_human(display_long)|uniprotkb:Plasma membrane-associated fatty acid-binding protein(gene name synonym)|uniprotkb:Transaminase A(gene name synonym)|uniprotkb:Glutamate oxaloacetate transaminase 2(gene name synonym)|uniprotkb:Fatty acid-binding protein(gene name synonym)|uniprotkb:GOT2(gene name)|psi-mi:GOT2(display_short)|uniprotkb:Kynurenine aminotransferase 4(gene name synonym)|uniprotkb:Kynurenine aminotransferase IV(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase 4(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase IV(gene name synonym)|uniprotkb:KYAT4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001273149.1|refseq:NP_002071.2|ensembl:ENSG00000125166(gene)|ensembl:ENST00000245206(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0009986"(cell surface)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0016597"(amino acid binding)|go:"GO:0019470"(4-hydroxyproline catabolic process)|go:"GO:0019550"(glutamate catabolic process to aspartate)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030315"(T-tubule)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P00505|rcsb pdb:5AX8|reactome:R-HSA-1614558|reactome:R-HSA-389661|reactome:R-HSA-70263|reactome:R-HSA-8963693|reactome:R-HSA-8964539 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:O1J4G1Kh9QJP6udcrZYeIKiic/g9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P00338 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O76021 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O75643 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_054733.2|ensembl:ENSG00000144028(gene)|ensembl:ENST00000323853(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:XP_016859092.1|dip:DIP-31659N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O75494 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353655|uniprotkb:Q5JRI3|uniprotkb:Q5JRI4|uniprotkb:A6NFM6|uniprotkb:A6NI42|uniprotkb:A6NIU7|uniprotkb:Q5JRH9|uniprotkb:Q5JRI2|uniprotkb:O60572|uniprotkb:Q96G09|uniprotkb:Q96P17|uniprotkb:Q5JRI0|intact:EBI-11103259|ensembl:ENSP00000420195|uniprotkb:B4DJP9 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:srs10_human(display_long)|uniprotkb:FUSIP1(gene name synonym)|uniprotkb:TASR(gene name synonym)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:FUSIP2(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym)|uniprotkb:40 kDa SR-repressor protein(gene name synonym)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short)|uniprotkb:Splicing factor SRp38(gene name synonym)|uniprotkb:SFRS13A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001177936.1|refseq:NP_001177934.1|refseq:NP_001177935.1|refseq:NP_006616.1|refseq:NP_473357.1|ensembl:ENSG00000188529(gene)|ensembl:ENST00000492112(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:O75494|reactome:R-HSA-72163|refseq:NP_001177938.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:abrRZLYWl3wlG2rHzVZMgej5EWk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O00567 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q92841 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P67936 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P01611 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-20594998|uniprotkb:A0A0B4J2E7|ensembl:ENSP00000482464 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:kvd12_human(display_long)|uniprotkb:Ig kappa chain V-I region Wes(gene name synonym)|uniprotkb:IGKV1D-12(gene name)|psi-mi:IGKV1D-12(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000278857(gene)|ensembl:ENST00000377032(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-2029482 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:sQr21ZmnYRkb2zmao+n64uIoIHA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q8N1N4 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1056564|uniprotkb:Q7RTT2|uniprotkb:Q5HYM7|uniprotkb:A8K4D6|ensembl:ENSP00000306261 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c78_human(display_long)|uniprotkb:KRT78(gene name)|psi-mi:KRT78(display_short)|uniprotkb:K5B(gene name synonym)|uniprotkb:KB40(gene name synonym)|uniprotkb:Cytokeratin-78(gene name synonym)|uniprotkb:Type-II keratin Kb40(gene name synonym)|uniprotkb:Keratin-5b(gene name synonym)|uniprotkb:Keratin-78(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001287743.1|refseq:NP_775487.2|ensembl:ENSG00000170423(gene)|ensembl:ENST00000304620(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:7DFQlPKPQ4Bu1Q5+nxLQufA7ghU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q86YZ3 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1047017|uniprotkb:Q5U1F4|ensembl:ENSP00000357791|uniprotkb:Q5DT20 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:horn_human(display_long)|uniprotkb:HRNR(gene name)|psi-mi:HRNR(display_short)|uniprotkb:S100A18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001009931.1|ensembl:ENSG00000197915(gene)|ensembl:ENST00000368801(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031424"(keratinization)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0043163"(cell envelope organization)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR033201|interpro:IPR034325|mint:Q86YZ3|reactome:R-HSA-6798695|ensembl:ENSP00000357791 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:j5ATFM7OQGbf5j+CZpJ3bJoadnc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q16629 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-398885|uniprotkb:Q564D3|intact:EBI-11107979|uniprotkb:B4DLU6|uniprotkb:G5E9M3|ensembl:ENSP00000325905 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:srsf7_human(display_long)|uniprotkb:SRSF7(gene name)|psi-mi:SRSF7(display_short)|uniprotkb:Splicing factor 9G8(gene name synonym)|uniprotkb:SFRS7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001026854.1|refseq:NP_001182375.1|dip:DIP-31790N|ensembl:ENSG00000115875(gene)|ensembl:ENST00000313117(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|mint:Q16629|rcsb pdb:2HVZ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:12lFDvstcW/ySFKb4LR8KF9AylI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15370 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15084 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:411bo7TdfeCtMvUqyBb7bofi5To9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08865 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08758 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-296601|ensembl:ENSP00000296511|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|uniprotkb:D3DNW7 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000164111(gene)|ensembl:ENST00000296511(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|reactome:R-HSA-114608|refseq:NP_001145.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O14979 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-299727|ensembl:ENSP00000295470|ensembl:ENSP00000422040|ensembl:ENSP00000483254|uniprotkb:Q6SPF2|uniprotkb:Q7KZ74|uniprotkb:Q7KZ75|uniprotkb:Q96IM0|uniprotkb:Q96S43 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrdl_human(display_long)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000152795(gene)|ensembl:ENST00000295470(transcript)|ensembl:ENST00000502762(transcript)|ensembl:ENST00000621267(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|mint:O14979|go:"GO:0003723"(RNA binding)|reactome:R-HSA-8950505|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034046"("poly(G) binding")|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001193929.1|refseq:NP_112740.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:oOnEEar8AtKO5G6ldehucaRr4kM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q02413 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1045757|intact:EBI-28968615|ensembl:ENSP00000257192|uniprotkb:B7Z845 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:dsg1_human(display_long)|uniprotkb:CDHF4(gene name synonym)|uniprotkb:Desmosomal glycoprotein 1(gene name synonym)|uniprotkb:Pemphigus foliaceus antigen(gene name synonym)|uniprotkb:DSG1(gene name)|psi-mi:DSG1(display_short)|uniprotkb:Cadherin family member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSP00000257192|refseq:NP_001933.2|ensembl:ENSG00000134760(gene)|ensembl:ENST00000257192(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q02413|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:CiRFIJ9IWOol9bQpLJPxH8JArtE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9NR30 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13617 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13242 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2949710|ensembl:ENSP00000229390|uniprotkb:Q52LD1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:srsf9_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)|uniprotkb:SFRS9(gene name synonym)|uniprotkb:SRP30C(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRp30C(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0006397"(mRNA processing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR034503|interpro:IPR034995|interpro:IPR035979|mint:Q13242|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|ensembl:ENSG00000111786(gene)|ensembl:ENST00000229390(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_003760.1|dip:DIP-40741N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:9x6TWFk1zN1YodjXBiwi/MtNJe49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q07955 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q05682 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P81605 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P78395 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-348325|ensembl:ENSP00000381726|ensembl:ENSP00000381728|ensembl:ENSP00000384343|ensembl:ENSP00000385198|ensembl:ENSP00000445097|ensembl:ENSP00000445675|ensembl:ENSP00000484066|ensembl:ENSP00000486330|ensembl:ENSP00000486485|uniprotkb:O43481|uniprotkb:Q8IXN8|uniprotkb:B2R6Y7 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:prame_human(display_long)|uniprotkb:PRAME(gene name)|psi-mi:PRAME(display_short)|uniprotkb:MAPE(gene name synonym)|uniprotkb:Preferentially expressed antigen of melanoma(gene name synonym)|uniprotkb:OIP4(gene name synonym)|uniprotkb:Opa-interacting protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001278644.1|refseq:NP_001278645.1|refseq:NP_001278646.1|refseq:NP_001278648.1|ensembl:ENSG00000185686(gene)|ensembl:ENSG00000275013(gene)|interpro:IPR032675|interpro:IPR026271|ensembl:ENST00000398743(transcript)|ensembl:ENST00000402697(transcript)|ensembl:ENST00000405655(transcript)|ensembl:ENST00000539862(transcript)|ensembl:ENST00000543184(transcript)|ensembl:ENST00000617728(transcript)|ensembl:ENST00000626503(transcript)|ensembl:ENST00000628830(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|ensembl:ENST00000398741(transcript)|refseq:NP_006106.1|refseq:NP_996836.1|refseq:NP_996837.1|refseq:NP_996838.1|refseq:NP_996839.1|refseq:NP_001305056.1|refseq:NP_001305055.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:VdJSwUPADlQ09QZ6P/x7jEc3fRw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62081 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P61247 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352378|uniprotkb:P33443|uniprotkb:P49241|uniprotkb:B2R4D4|intact:EBI-3440915|uniprotkb:D3DP05|ensembl:ENSP00000346050 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs3a_human(display_long)|uniprotkb:RPS3A(gene name)|psi-mi:RPS3A(display_short)|uniprotkb:MFTL(gene name synonym)|uniprotkb:FTE1(gene name synonym)|uniprotkb:v-fos transformation effector protein(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000997.1|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:4V6X|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000145425(gene)|ensembl:ENST00000274065(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001593(Ribosomal protein S3Ae)|interpro:IPR018281|interpro:IPR027500|mint:P61247|rcsb pdb:4UG0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6OM7|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-29408N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:g1TMzz8OFWEuhrRCoecj7KW0qTQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P46781 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351206|uniprotkb:Q4QRK7|uniprotkb:Q9BVZ0|ensembl:ENSP00000302896|ensembl:ENSP00000375632|ensembl:ENSP00000375633|ensembl:ENSP00000478449|ensembl:ENSP00000479917|ensembl:ENSP00000480135|ensembl:ENSP00000480662|ensembl:ENSP00000481194|ensembl:ENSP00000481553|ensembl:ENSP00000481655|ensembl:ENSP00000481764|ensembl:ENSP00000481822|ensembl:ENSP00000482023|ensembl:ENSP00000482274|ensembl:ENSP00000482338|ensembl:ENSP00000482475|ensembl:ENSP00000483179|ensembl:ENSP00000484394|uniprotkb:A9C4C1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs9_human(display_long)|uniprotkb:RPS9(gene name)|psi-mi:RPS9(display_short)|uniprotkb:Small ribosomal subunit protein uS4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001004.2|refseq:NP_001308630.1|refseq:NP_001308631.1|refseq:NP_001308633.1|ensembl:ENSG00000170889(gene)|ensembl:ENSG00000274005(gene)|ensembl:ENSG00000274626(gene)|ensembl:ENSG00000274646(gene)|ensembl:ENSG00000274950(gene)|ensembl:ENSG00000275323(gene)|ensembl:ENSG00000277079(gene)|ensembl:ENSG00000277359(gene)|ensembl:ENSG00000278081(gene)|ensembl:ENSG00000278270(gene)|ensembl:ENST00000302907(transcript)|ensembl:ENST00000391752(transcript)|ensembl:ENST00000391753(transcript)|ensembl:ENST00000610826(transcript)|ensembl:ENST00000610953(transcript)|ensembl:ENST00000611921(transcript)|ensembl:ENST00000614737(transcript)|ensembl:ENST00000615346(transcript)|ensembl:ENST00000616082(transcript)|ensembl:ENST00000616536(transcript)|ensembl:ENST00000616839(transcript)|ensembl:ENST00000616877(transcript)|ensembl:ENST00000616928(transcript)|ensembl:ENST00000617291(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000618751(transcript)|go:"GO:0005829"(cytosol)|ensembl:ENST00000619229(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|ensembl:ENST00000620720(transcript)|ensembl:ENST00000620940(transcript)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|mint:P46781|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|go:"GO:0005634"(nucleus)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|go:"GO:0005654"(nucleoplasm)|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P39023 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P34897 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P26599 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-350540|ensembl:ENSP00000014112|intact:EBI-744534|uniprotkb:Q9BUQ0 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ptbp1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:PTB(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym)|uniprotkb:57 kDa RNA-binding protein PPTB-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002810.1|refseq:NP_114367.1|refseq:NP_114368.1|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0016020"(membrane)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034798|interpro:IPR035000|interpro:IPR035001|interpro:IPR035979|mint:P26599|rcsb pdb:1QM9|rcsb pdb:1SJQ|ensembl:ENSG00000011304(gene)|ensembl:ENST00000349038(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|rcsb pdb:2AD9|rcsb pdb:2ADB|rcsb pdb:2ADC|rcsb pdb:2EVZ|rcsb pdb:2N3O|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|rcsb pdb:1SJR - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:fkSnYJELgHxDP0oAQEjBmSX0HIs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P23284 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000933.1|ensembl:ENSG00000166794(gene)|ensembl:ENST00000300026(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|reactome:R-HSA-1650814 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P18124 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P11388 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-539628|uniprotkb:Q9HB26|uniprotkb:Q71UN1|uniprotkb:Q71UQ5|uniprotkb:Q9HB24|uniprotkb:Q9HB25|uniprotkb:Q9UP44|uniprotkb:Q9UQP9|uniprotkb:B2RTS1|intact:EBI-2556496|ensembl:ENSP00000411532 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:top2a_human(display_long)|uniprotkb:DNA topoisomerase II, alpha isozyme(gene name synonym)|uniprotkb:TOP2A(gene name)|psi-mi:TOP2A(display_short)|uniprotkb:TOP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001058.2|ensembl:ENSG00000131747(gene)|ensembl:ENST00000423485(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048511"(rhythmic process)|go:"GO:1905463"(negative regulation of DNA duplex unwinding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR012542(DTHCT)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|mint:P11388|rcsb pdb:1LWZ|rcsb pdb:1ZXM|rcsb pdb:4FM9|rcsb pdb:4R1F|rcsb pdb:5GWK|rcsb pdb:5NNE|rcsb pdb:6ZY5|rcsb pdb:6ZY6|rcsb pdb:6ZY7|rcsb pdb:6ZY8|reactome:R-HSA-1362277|reactome:R-HSA-4615885|rcsb pdb:1ZXN|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006266"(DNA ligation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0019899"(enzyme binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045870"(positive regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-33887N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:WFhFsTLF3XG/CVgT4+TBNCovXiM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08621 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1049228|uniprotkb:P78493|uniprotkb:P78494|uniprotkb:Q15364|uniprotkb:Q15686|uniprotkb:Q15687|uniprotkb:Q15689|uniprotkb:Q99377|uniprotkb:Q9UE45|uniprotkb:Q9UE46|uniprotkb:Q9UE47|uniprotkb:Q9UE48|uniprotkb:Q9UFQ6|intact:EBI-3190943|uniprotkb:B3KUA3|ensembl:ENSP00000472998 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ru17_human(display_long)|uniprotkb:SNRNP70(gene name)|psi-mi:SNRNP70(display_short)|uniprotkb:RPU1(gene name synonym)|uniprotkb:U1AP1(gene name synonym)|uniprotkb:RNPU1Z(gene name synonym)|uniprotkb:SNRP70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003080.2|refseq:NP_001287998.1|ensembl:ENSG00000104852(gene)|ensembl:ENST00000598441(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:1904715"(negative regulation of chaperone-mediated autophagy)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR022023|interpro:IPR034143|interpro:IPR035979|mint:P08621|rcsb pdb:2L5I|rcsb pdb:2L5J|rcsb pdb:3CW1|rcsb pdb:3PGW|rcsb pdb:4PJO|rcsb pdb:4PKD|rcsb pdb:6QX9|rcsb pdb:7B0Y|reactome:R-HSA-72163|dip:DIP-29406N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/P72B69q5f0TX4vTr4GuRrtgiRM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P07195 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P05387 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P04406 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P52597 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P0C0S5 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1199859|uniprotkb:P17317|uniprotkb:Q6I9U0|uniprotkb:B2RD56|ensembl:ENSP00000296417 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:h2az_human(display_long)|uniprotkb:H2AZ1(gene name)|psi-mi:H2AZ1(display_short)|uniprotkb:H2AFZ(gene name synonym)|uniprotkb:H2AZ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002097.1|ensembl:ENSG00000164032(gene)|ensembl:ENST00000296417(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S5|rcsb pdb:1F66|rcsb pdb:3WA9|rcsb pdb:4CAY|rcsb pdb:4NFT|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5CHL|rcsb pdb:5FUG|rcsb pdb:5Z30|rcsb pdb:6JOU|rcsb pdb:6KO2|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-38593N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:0FrzM1TXlduSQ0NNVl0C9uqCUGI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q6KB66 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-3046635|ensembl:ENSP00000378292|uniprotkb:Q7Z3Q0|uniprotkb:Q6P1A5 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c80_human(display_long)|uniprotkb:KRT80(gene name)|psi-mi:KRT80(display_short)|uniprotkb:KB20(gene name synonym)|uniprotkb:Cytokeratin-80(gene name synonym)|uniprotkb:Keratin-80(gene name synonym)|uniprotkb:Type-II keratin Kb20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000167767(gene)|ensembl:ENST00000394815(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|interpro:IPR003054(Type II keratin)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0005737"(cytoplasm)|refseq:NP_001074961.1|refseq:NP_872313.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:bFGJxzEmmWY5N3kaTviqyx5qSkY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P68431 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q13838 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q07021 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q01105 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62701 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P49411 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P42704 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P38159 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P35579 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P35232 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P30101 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P27797 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P23396 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P16403 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O95816 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P12236 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P05141 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q14CN4 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1221280|uniprotkb:Q8NA87|uniprotkb:Q8WWZ0|uniprotkb:Q8WWY9|intact:EBI-11031454|uniprotkb:B4DEI8|uniprotkb:H9KV51|ensembl:ENSP00000293745|ensembl:ENSP00000441160 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c72_human(display_long)|uniprotkb:KRT72(gene name)|psi-mi:KRT72(display_short)|uniprotkb:Keratin-72(gene name synonym)|uniprotkb:K6IRS2(gene name synonym)|uniprotkb:KB35(gene name synonym)|uniprotkb:KRT6(gene name synonym)|uniprotkb:KRT6IRS2(gene name synonym)|uniprotkb:Cytokeratin-72(gene name synonym)|uniprotkb:Type-II keratin Kb35(gene name synonym)|uniprotkb:Type II inner root sheath-specific keratin-K6irs2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001139697.1|refseq:NP_001139698.1|refseq:NP_542785.1|ensembl:ENSG00000170486(gene)|ensembl:ENST00000293745(transcript)|ensembl:ENST00000537672(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:h6CpYy35iQ46Uka3QpurYjoGWBI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O60506 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P17844 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P06753 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q06830 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P31689 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P20700 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15149 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q07020 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352694|intact:EBI-8456577|intact:MINT-8429255|uniprotkb:F8VWC5|uniprotkb:Q8WTZ6|ensembl:ENSP00000447001 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl18_human(display_long)|uniprotkb:RPL18(gene name)|psi-mi:RPL18(display_short)|uniprotkb:Large ribosomal subunit protein eL18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000970.1|ensembl:ENSG00000063177(gene)|ensembl:ENST00000549920(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000039(Ribosomal protein L18e)|interpro:IPR021131|interpro:IPR021132|interpro:IPR036227|mint:Q07020|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001257419.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:GgzBcLEQgBqbApFlaQIU2jktkAE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P52272 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-486809|uniprotkb:Q9Y492|uniprotkb:Q15584|uniprotkb:Q8WZ44|uniprotkb:Q96H56|uniprotkb:Q9BWL9|intact:EBI-28985795|ensembl:ENSP00000325376 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrpm_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005959.2|refseq:NP_112480.2|ensembl:ENSG00000099783(gene)|ensembl:ENST00000325495(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:P52272|rcsb pdb:2DGV|rcsb pdb:2DH9|rcsb pdb:2DO0|rcsb pdb:2OT8|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-29336N|ensembl:ENSP00000325376|ensembl:ENST00000348943|ensembl:ENSP00000325732 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:5FnCgrz0xltEkgw3yh70KP2jz5g9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P48643 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P14923 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P12956 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08195 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O75367 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2868511|uniprotkb:Q7Z5E3|uniprotkb:Q9UP96|uniprotkb:Q9H8P3|uniprotkb:Q503A8|uniprotkb:O75377|uniprotkb:Q96D41|ensembl:ENSP00000423563|ensembl:ENSP00000424971 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:h2ay_human(display_long)|uniprotkb:MACROH2A1(gene name)|psi-mi:MACROH2A1(display_short)|uniprotkb:H2AFY(gene name synonym)|uniprotkb:Histone H2A.y(gene name synonym)|uniprotkb:Medulloblastoma antigen MU-MB-50.205(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:XP_011542031.1|refseq:XP_011542032.1|refseq:NP_001035248.1|refseq:NP_004884.1|refseq:NP_613075.1|refseq:NP_613258.2|dip:DIP-44283N|ensembl:ENSG00000113648(gene)|ensembl:ENST00000510038(transcript)|ensembl:ENST00000511689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0007549"(dosage compensation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|interpro:IPR032454|interpro:IPR035796|interpro:IPR043472|mint:O75367|rcsb pdb:1U35|rcsb pdb:1ZR3|rcsb pdb:1ZR5|rcsb pdb:2F8N|rcsb pdb:2FXK|rcsb pdb:3HQH|rcsb pdb:3HSV|rcsb pdb:3IID|rcsb pdb:3IIF|rcsb pdb:3IVB|rcsb pdb:5IIT|rcsb pdb:5LNC|interpro:IPR002119(Histone H2A) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:0FCoM0/4mTtnc7cPDUleKuZ3HgM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q96KK5 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P31943 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P51991 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P35637 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q02878 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P55072 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P43243 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q05639 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P62805 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P27824 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P06576 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O43390 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P23246 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q99832 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P50991 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P10809 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P06748 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P68104 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P02768 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-714423|ensembl:ENSP00000295897|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:1E78|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051087"(chaperone binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7JWN|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-879518|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|rcsb pdb:6WUW|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:1E7A|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6HSC|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|refseq:NP_000468.1|dip:DIP-29902N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P0CG48 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-3390054|ensembl:ENSP00000344818|ensembl:ENSP00000441543|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5656121|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9613829|ensembl:ENSG00000150991(gene)|ensembl:ENST00000339647(transcript)|ensembl:ENST00000536769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:1ZO6|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|interpro:IPR000626(Ubiquitin)|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2MI8|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3PTF|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6EQI|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|refseq:NP_066289.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P07910 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P78527 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P68371 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08779 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356410|uniprotkb:P30654|uniprotkb:Q16402|uniprotkb:Q9UBG8|uniprotkb:A8K488|ensembl:ENSP00000301653 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k1c16_human(display_long)|uniprotkb:KRT16(gene name)|psi-mi:KRT16(display_short)|uniprotkb:KRT16A(gene name synonym)|uniprotkb:Keratin-16(gene name synonym)|uniprotkb:Cytokeratin-16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005548.2|ensembl:ENSG00000186832(gene)|ensembl:ENST00000301653(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007568"(aging)|go:"GO:0030216"(keratinocyte differentiation)|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031424"(keratinization)|go:"GO:0042633"(hair cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051546"(keratinocyte migration)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08779 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:NkPTLkWquNNlGYbrXaRkyRmKvmM9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08238 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P07900 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P09651 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q9BQE3 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P19013 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2371606|uniprotkb:Q6GTR8|uniprotkb:Q96LA7|uniprotkb:Q9BTL1|intact:EBI-22121113|uniprotkb:B4DRS2|uniprotkb:F8VS64|intact:EBI-22010019|intact:EBI-28973341|ensembl:ENSP00000448220 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c4_human(display_long)|uniprotkb:KRT4(gene name)|psi-mi:KRT4(display_short)|uniprotkb:CYK4(gene name synonym)|uniprotkb:Cytokeratin-4(gene name synonym)|uniprotkb:Keratin-4(gene name synonym)|uniprotkb:Type-II keratin Kb4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSP00000448220|refseq:NP_002263.3|ensembl:ENSG00000170477(gene)|ensembl:ENST00000551956(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009986"(cell surface)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P19013|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:WBLRjdlqvNYbC7R2ZSNON6QLcOU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q7Z794 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-3045529|intact:EBI-28984254|ensembl:ENSP00000342710|uniprotkb:Q7RTS8 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c1b_human(display_long)|uniprotkb:KRT77(gene name)|psi-mi:KRT77(display_short)|uniprotkb:KRT1B(gene name synonym)|uniprotkb:Cytokeratin-1B(gene name synonym)|uniprotkb:Keratin-77(gene name synonym)|uniprotkb:Type-II keratin Kb39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000189182(gene)|ensembl:ENST00000341809(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_778253.2|ensembl:ENSP00000342710 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:+gHbNvYkE7DhN5LqnFk9EY1/A409606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P07437 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P25705 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P49368 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P19338 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P01857 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356114|ensembl:ENSP00000374991|ensembl:ENSP00000488387 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000211896(gene)|ensembl:ENSG00000277633(gene)|ensembl:ENST00000390549(transcript)|ensembl:ENST00000631466(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:1I7Z|rcsb pdb:3WJL|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:3WKN|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|reactome:R-HSA-166663|rcsb pdb:4XNZ|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:1YK8rrTDnOYYKW5wHI48/rYlr5o9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:O60814 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P11021 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P38646 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P14625 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P78371 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P68032 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P22626 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P17987 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q00839 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P40227 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08729 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-297833|uniprotkb:Q92676|uniprotkb:Q9BUD8|uniprotkb:Q9Y3R7|ensembl:ENSP00000329243 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c7_human(display_long)|uniprotkb:KRT7(gene name)|psi-mi:KRT7(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:Cytokeratin-7(gene name synonym)|uniprotkb:Sarcolectin(gene name synonym)|uniprotkb:Keratin-7(gene name synonym)|uniprotkb:Type-II keratin Kb7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000135480(gene)|ensembl:ENST00000331817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P08729|rcsb pdb:4XIF|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_005547.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/JagfI/WbHqqQXLNgQRXSJEPQpo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15233 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08107 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 intact:EBI-11820565 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 - psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:1304"(molecule set) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N - - - comment:P0DMV8,P0DMV9 figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 - - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P61978 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P07355 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P15924 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|uniprotkb:D7RX09|ensembl:ENSP00000369129 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001305963.1|refseq:NP_001008844.1|refseq:NP_004406.2|go:"GO:0014704"(intercalated disc)|go:"GO:0005916"(fascia adherens)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-109N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q15007 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q08211 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P50990 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P02533 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-702178|uniprotkb:Q14715|uniprotkb:Q53XY3|uniprotkb:Q9BUE3|uniprotkb:Q9UBN2|uniprotkb:Q9UBN3|uniprotkb:Q9UCY4|ensembl:ENSP00000167586 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k1c14_human(display_long)|uniprotkb:Cytokeratin-14(gene name synonym)|uniprotkb:KRT14(gene name)|psi-mi:KRT14(display_short)|uniprotkb:Keratin-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000517.2|dip:DIP-33874N|ensembl:ENSG00000186847(gene)|ensembl:ENST00000167586(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0008544"(epidermis development)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042633"(hair cycle)|go:"GO:0045095"(keratin filament)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990254"(keratin filament binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P02533|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:IO1k6S8FB65jQr4GNwhKuxZ1ohg9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P05783 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P31327 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-536811|uniprotkb:O43774|uniprotkb:Q7Z5I5|uniprotkb:B7Z818|uniprotkb:Q53TL5|uniprotkb:J3KQL0|uniprotkb:Q59HF8|ensembl:ENSP00000233072|ensembl:ENSP00000500537|ensembl:ENSP00000501022|ensembl:ENSP00000501073 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:cpsm_human(display_long)|uniprotkb:Carbamoyl-phosphate synthetase I(gene name synonym)|uniprotkb:CPS1(gene name)|psi-mi:CPS1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001116105.1|refseq:NP_001116106.1|refseq:NP_001866.2|refseq:XP_011508943.1|refseq:XP_011508944.1|refseq:XP_011508945.1|refseq:XP_011508946.1|ensembl:ENSG00000021826(gene)|ensembl:ENST00000233072(transcript)|ensembl:ENST00000673510(transcript)|ensembl:ENST00000673630(transcript)|ensembl:ENST00000673711(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0004087"("carbamoyl-phosphate synthase (ammonia) activity")|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014075"(response to amine)|go:"GO:0016595"(glutamate binding)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0032094"(response to food)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043200"(response to amino acid)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046209"(nitric oxide metabolic process)|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0055081"(anion homeostasis)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070409"(carbamoyl phosphate biosynthetic process)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0072341"(modified amino acid binding)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036914|mint:P31327|rcsb pdb:2YVQ|rcsb pdb:4UTR|rcsb pdb:4UTV|rcsb pdb:4UTX|rcsb pdb:4UTZ|rcsb pdb:4UU7|rcsb pdb:4UU8|rcsb pdb:4UUA|rcsb pdb:4UUB|rcsb pdb:5DOT|rcsb pdb:5DOU|rcsb pdb:5OJO|rcsb pdb:6UEL|rcsb pdb:6W2J|reactome:R-HSA-70635 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:497s02igPCWuQcU4lVrMpl5SRig9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P02545 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P60709 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q69YN4 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P21333 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P08670 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P04259 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-740907|ensembl:ENSP00000252252|uniprotkb:P48669 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c6b_human(display_long)|uniprotkb:Cytokeratin-6B(gene name synonym)|uniprotkb:Keratin-6B(gene name synonym)|uniprotkb:KRT6B(gene name)|psi-mi:KRT6B(display_short)|uniprotkb:K6B(gene name synonym)|uniprotkb:KRTL1(gene name synonym)|uniprotkb:Type-II keratin Kb10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_005546.2|ensembl:ENSG00000185479(gene)|ensembl:ENST00000252252(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0007398"(ectoderm development)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P04259|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:lFuNGZdQm4pftz53qbflLTyyAaQ9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P11142 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P13647 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-702187|uniprotkb:Q6PI71|uniprotkb:Q6UBJ0|uniprotkb:Q8TA91|ensembl:ENSP00000252242 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c5_human(display_long)|uniprotkb:Cytokeratin-5(gene name synonym)|uniprotkb:58 kDa cytokeratin(gene name synonym)|uniprotkb:KRT5(gene name)|psi-mi:KRT5(display_short)|uniprotkb:Keratin-5(gene name synonym)|uniprotkb:Type-II keratin Kb5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000415.2|dip:DIP-39N|ensembl:ENSG00000186081(gene)|ensembl:ENST00000252242(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P13647|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:BdtVgSlWFYS/+zyXLNxvrcSWc4I9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P05787 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-297852|uniprotkb:Q14099|uniprotkb:Q14716|uniprotkb:Q14717|uniprotkb:Q53GJ0|uniprotkb:Q6DHW5|uniprotkb:Q6GMY0|uniprotkb:Q6P4C7|uniprotkb:Q96J60|ensembl:ENSP00000293308|ensembl:ENSP00000447402|ensembl:ENSP00000447566|uniprotkb:A8K4H3|uniprotkb:B0AZN5|uniprotkb:F8VXB4 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c8_human(display_long)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:KRT8(gene name)|psi-mi:KRT8(display_short)|uniprotkb:CYK8(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_001243222.1|ensembl:ENSG00000170421(gene)|ensembl:ENST00000293308(transcript)|ensembl:ENST00000546897(transcript)|ensembl:ENST00000552551(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0051707"(response to other organism)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P05787|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002264.1|dip:DIP-424N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:zyV8eOjx426ehjJYK4jsizORUws9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P35527 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-356382|uniprotkb:O00109|uniprotkb:Q0IJ47|uniprotkb:Q14665|ensembl:ENSP00000246662 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k1c9_human(display_long)|uniprotkb:KRT9(gene name)|psi-mi:KRT9(display_short)|uniprotkb:Keratin-9(gene name synonym)|uniprotkb:Cytokeratin-9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000217.2|ensembl:ENSG00000171403(gene)|ensembl:ENST00000246662(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0043588"(skin development)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P35527|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:m4EXfxbK2t1/EmI04YODKTJ02Zw9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P35908 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-1247312|uniprotkb:Q4VAQ2|ensembl:ENSP00000310861 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k22e_human(display_long)|uniprotkb:KRT2(gene name)|psi-mi:KRT2(display_short)|uniprotkb:KRT2A(gene name synonym)|uniprotkb:KRT2E(gene name synonym)|uniprotkb:Cytokeratin-2e(gene name synonym)|uniprotkb:Keratin-2e(gene name synonym)|uniprotkb:Type-II keratin Kb2(gene name synonym)|uniprotkb:Keratin-2 epidermis(gene name synonym)|uniprotkb:Epithelial keratin-2e(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_000414.2|ensembl:ENSG00000172867(gene)|ensembl:ENST00000309680(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003334"(keratinocyte development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|go:"GO:0032980"(keratinocyte activation)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045095"(keratin filament)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P35908|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0051546"(keratinocyte migration) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:T7LeB8nkZzNjUb8DWdkxbrl5f789606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:Q86U44 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P13645 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-465144|ensembl:ENSP00000269576|uniprotkb:Q14664|uniprotkb:Q8N175 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k1c10_human(display_long)|uniprotkb:KRT10(gene name)|psi-mi:KRT10(display_short)|uniprotkb:Cytokeratin-10(gene name synonym)|uniprotkb:KPP(gene name synonym)|uniprotkb:Keratin-10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000186395(gene)|ensembl:ENST00000269576(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P13645|rcsb pdb:3ASW|rcsb pdb:4F1Z|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6EC0|rcsb pdb:6UUI|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000412.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:z100yyq3b63P0ARy2lE2ELyJeik9606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE5 uniprotkb:P04264 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-298429|uniprotkb:Q14720|uniprotkb:Q6GSJ0|uniprotkb:B2RA01|uniprotkb:Q9H298|ensembl:ENSP00000252244|uniprotkb:P85925|uniprotkb:P86104 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:k2c1_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:KRTA(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Cytokeratin-1(gene name synonym)|uniprotkb:67 kDa cytokeratin(gene name synonym)|uniprotkb:Hair alpha protein(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595531|imex:IM-26525-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_006112.3|ensembl:ENSG00000167768(gene)|ensembl:ENST00000252244(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045095"(keratin filament)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR032449|interpro:IPR039008|mint:P04264|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6UUI|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2021/11/30 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:TeAC3i2hWTS2lgXT0i4agp9nv349606 - false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86U44 uniprotkb:Q13263 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595883|imex:IM-26525-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/26 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:fmvr0kieOjtKZm+hOPqPJa3GHC8 false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86U44 uniprotkb:Q5T200 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2679720|uniprotkb:Q7Z7J3|uniprotkb:Q5T1Z9|uniprotkb:O94936|uniprotkb:Q9H0L6|uniprotkb:Q8NDT6|uniprotkb:A2A323|ensembl:ENSP00000242848 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:zc3hd_human(display_long)|uniprotkb:KIAA0853(gene name synonym)|uniprotkb:ZC3H13(gene name)|psi-mi:ZC3H13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595883|imex:IM-26525-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_055885.3|refseq:XP_005266369.1|ensembl:ENSG00000123200(gene)|ensembl:ENST00000242848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|mint:Q5T200|refseq:NP_001070256.1|refseq:NP_001317493.1|refseq:NP_001317494.1|refseq:NP_001317495.1|refseq:NP_001317496.1 - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/26 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:uqLw8ZjXiweaBggvvS1ue4FvNf09606 rigid:fmvr0kieOjtKZm+hOPqPJa3GHC8 false ha tag:n-n|flag tag:n-n sufficient binding region:1107-1668|flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86U44 uniprotkb:Q75N03 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|intact:EBI-28973894|ensembl:ENSP00000401277|uniprotkb:B7ZM03 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595883|imex:IM-26525-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N ensembl:ENST00000222597|ensembl:ENSP00000222597|ensembl:ENSP00000401277|ensembl:ENSG00000105879(gene)|ensembl:ENST00000440859(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|refseq:NP_079090.2|refseq:NP_001271220.1 - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/26 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606 rigid:fmvr0kieOjtKZm+hOPqPJa3GHC8 false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86U44 uniprotkb:Q69YN4 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20595883|imex:IM-26525-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/26 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rigid:fmvr0kieOjtKZm+hOPqPJa3GHC8 false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HCE5 uniprotkb:Q13263 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596214|imex:IM-26525-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/27 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:tPb9VnaUMiSkN3t2F4N3CTpt0lI false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HCE5 uniprotkb:Q5T200 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2679720|uniprotkb:Q7Z7J3|uniprotkb:Q5T1Z9|uniprotkb:O94936|uniprotkb:Q9H0L6|uniprotkb:Q8NDT6|uniprotkb:A2A323|ensembl:ENSP00000242848 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:zc3hd_human(display_long)|uniprotkb:KIAA0853(gene name synonym)|uniprotkb:ZC3H13(gene name)|psi-mi:ZC3H13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596214|imex:IM-26525-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_055885.3|refseq:XP_005266369.1|ensembl:ENSG00000123200(gene)|ensembl:ENST00000242848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|mint:Q5T200|refseq:NP_001070256.1|refseq:NP_001317493.1|refseq:NP_001317494.1|refseq:NP_001317495.1|refseq:NP_001317496.1 - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/27 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:uqLw8ZjXiweaBggvvS1ue4FvNf09606 rigid:tPb9VnaUMiSkN3t2F4N3CTpt0lI false ha tag:n-n|flag tag:n-n sufficient binding region:1107-1668|flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HCE5 uniprotkb:Q75N03 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|intact:EBI-28973894|ensembl:ENSP00000401277|uniprotkb:B7ZM03 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596214|imex:IM-26525-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENST00000222597|ensembl:ENSP00000222597|ensembl:ENSP00000401277|ensembl:ENSG00000105879(gene)|ensembl:ENST00000440859(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|refseq:NP_079090.2|refseq:NP_001271220.1 - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/27 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606 rigid:tPb9VnaUMiSkN3t2F4N3CTpt0lI false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HCE5 uniprotkb:Q69YN4 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596214|imex:IM-26525-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/27 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rigid:tPb9VnaUMiSkN3t2F4N3CTpt0lI false ha tag:n-n|flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15007 uniprotkb:Q13263 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596230|imex:IM-26525-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/27 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:f2/U7WunG2Ed3PedkzaAGVqk3dI false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15007 uniprotkb:Q5T200 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2679720|uniprotkb:Q7Z7J3|uniprotkb:Q5T1Z9|uniprotkb:O94936|uniprotkb:Q9H0L6|uniprotkb:Q8NDT6|uniprotkb:A2A323|ensembl:ENSP00000242848 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:zc3hd_human(display_long)|uniprotkb:KIAA0853(gene name synonym)|uniprotkb:ZC3H13(gene name)|psi-mi:ZC3H13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596230|imex:IM-26525-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_055885.3|refseq:XP_005266369.1|ensembl:ENSG00000123200(gene)|ensembl:ENST00000242848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|mint:Q5T200|refseq:NP_001070256.1|refseq:NP_001317493.1|refseq:NP_001317494.1|refseq:NP_001317495.1|refseq:NP_001317496.1 - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/27 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:uqLw8ZjXiweaBggvvS1ue4FvNf09606 rigid:f2/U7WunG2Ed3PedkzaAGVqk3dI false flag tag:n-n|ha tag:n-n sufficient binding region:1107-1668|flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15007 uniprotkb:Q75N03 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|intact:EBI-28973894|ensembl:ENSP00000401277|uniprotkb:B7ZM03 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596230|imex:IM-26525-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 ensembl:ENST00000222597|ensembl:ENSP00000222597|ensembl:ENSP00000401277|ensembl:ENSG00000105879(gene)|ensembl:ENST00000440859(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|refseq:NP_079090.2|refseq:NP_001271220.1 - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/27 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606 rigid:f2/U7WunG2Ed3PedkzaAGVqk3dI false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15007 uniprotkb:Q69YN4 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596230|imex:IM-26525-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 - - - figure legend:Fig. 1B|comment:"HNRNPH (heterogeneous nuclear ribonucleoprotein H was also observed but could not be mapped to a single gene product. Its interaction with this complex was RNA-dependent."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/06/27 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rigid:f2/U7WunG2Ed3PedkzaAGVqk3dI false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q86U44 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596263|imex:IM-26525-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N - - - figure legend:Fig. 4B|comment:Binding is RNA-independent|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/17 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rigid:/MOjN8J6Sm7gDK86w0MTTbjtyY0 false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q15007 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596263|imex:IM-26525-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 - - - figure legend:Fig. 4B|comment:Binding is RNA-independent|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/17 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rigid:/MOjN8J6Sm7gDK86w0MTTbjtyY0 false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q5T200 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-2679720|uniprotkb:Q7Z7J3|uniprotkb:Q5T1Z9|uniprotkb:O94936|uniprotkb:Q9H0L6|uniprotkb:Q8NDT6|uniprotkb:A2A323|ensembl:ENSP00000242848 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:zc3hd_human(display_long)|uniprotkb:KIAA0853(gene name synonym)|uniprotkb:ZC3H13(gene name)|psi-mi:ZC3H13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596263|imex:IM-26525-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 refseq:NP_055885.3|refseq:XP_005266369.1|ensembl:ENSG00000123200(gene)|ensembl:ENST00000242848(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|mint:Q5T200|refseq:NP_001070256.1|refseq:NP_001317493.1|refseq:NP_001317494.1|refseq:NP_001317495.1|refseq:NP_001317496.1 - - - figure legend:Fig. 4B|comment:Binding is RNA-independent|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/17 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:uqLw8ZjXiweaBggvvS1ue4FvNf09606 rigid:/MOjN8J6Sm7gDK86w0MTTbjtyY0 false flag tag:n-n sufficient binding region:1107-1668|tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q75N03 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|intact:EBI-28973894|ensembl:ENSP00000401277|uniprotkb:B7ZM03 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596263|imex:IM-26525-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 ensembl:ENST00000222597|ensembl:ENSP00000222597|ensembl:ENSP00000401277|ensembl:ENSG00000105879(gene)|ensembl:ENST00000440859(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|refseq:NP_079090.2|refseq:NP_001271220.1 - - - figure legend:Fig. 4B|comment:Binding is RNA-independent|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/17 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606 rigid:/MOjN8J6Sm7gDK86w0MTTbjtyY0 false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q9HCE5 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596263|imex:IM-26525-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N - - - figure legend:Fig. 4B|comment:Binding is RNA-independent|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/17 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rigid:/MOjN8J6Sm7gDK86w0MTTbjtyY0 false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q86U44 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596319|imex:IM-26525-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N - - - figure legend:Fig. 4B|comment:Binding is RNA-independant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/18 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rigid:2Lzt0zFwrIFJtq1nMmpmgVwkwyE false flag tag:n-n|sufficient binding region:1-1130 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q13263 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596319|imex:IM-26525-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Fig. 4B|comment:Binding is RNA-independant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/18 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:2Lzt0zFwrIFJtq1nMmpmgVwkwyE false flag tag:n-n|sufficient binding region:1-1130 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q75N03 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|intact:EBI-28973894|ensembl:ENSP00000401277|uniprotkb:B7ZM03 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596319|imex:IM-26525-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 ensembl:ENST00000222597|ensembl:ENSP00000222597|ensembl:ENSP00000401277|ensembl:ENSG00000105879(gene)|ensembl:ENST00000440859(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|refseq:NP_079090.2|refseq:NP_001271220.1 - - - figure legend:Fig. 4B|comment:Binding is RNA-independant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/18 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606 rigid:2Lzt0zFwrIFJtq1nMmpmgVwkwyE false flag tag:n-n|sufficient binding region:1-1130 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q9HCE5 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20596319|imex:IM-26525-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N - - - figure legend:Fig. 4B|comment:Binding is RNA-independant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/18 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rigid:2Lzt0zFwrIFJtq1nMmpmgVwkwyE false flag tag:n-n|sufficient binding region:1-1130 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:O43809 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20626915|imex:IM-26525-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - - figure legend:Fig. 5A|comment:Binding is RNA-dependent|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/18 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:6hl8lIguoGIidmDJ2yEQFebTFMo false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q69YN4 uniprotkb:Q16630 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774 psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yue et al. (2017) pubmed:29507755|imex:IM-26525 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-20626915|imex:IM-26525-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 refseq:NP_008938.2|refseq:NP_001287876.1|ensembl:ENSG00000111605(gene)|ensembl:ENST00000435070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042382"(paraspeckles)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990448"(exon-exon junction complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|reactome:R-HSA-1839117|reactome:R-HSA-5655302|dip:DIP-34501N - - - figure legend:Fig. 5A|comment:Binding is RNA-dependent|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/06/26 2018/07/18 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606 rigid:6hl8lIguoGIidmDJ2yEQFebTFMo false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)