#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A0A6I8RQZ3 uniprotkb:A0A6I8RQZ3 intact:EBI-25339071|ensembl:ENSXETP00000087439 intact:EBI-25339071|ensembl:ENSXETP00000087439 psi-mi:a0a6i8rqz3_xentr(display_long)|uniprotkb:trpv4(gene name)|psi-mi:trpv4(display_short) psi-mi:a0a6i8rqz3_xentr(display_long)|uniprotkb:trpv4(gene name)|psi-mi:trpv4(display_short) psi-mi:"MI:0410"(3D electron microscopy) Deng et al. (2018) pubmed:29483651|imex:IM-26824 taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)") taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21005553|imex:IM-26824-1|wwpdb:6BBJ|emdb:EMD-7075 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSXETG00000018609(gene)|go:"GO:0005216"(ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0098703"(calcium ion import across plasma membrane)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR008348(Vanilloid receptor 2)|interpro:IPR020683|interpro:IPR024862|interpro:IPR036770|ensembl:ENSXETT00000086064(transcript)|uniprotkb:A0A5G3JN24(uniprot-removed-ac)|refseq:XP_002932129.1 ensembl:ENSXETG00000018609(gene)|go:"GO:0005216"(ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0098703"(calcium ion import across plasma membrane)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR008348(Vanilloid receptor 2)|interpro:IPR020683|interpro:IPR024862|interpro:IPR036770|ensembl:ENSXETT00000086064(transcript)|uniprotkb:A0A5G3JN24(uniprot-removed-ac)|refseq:XP_002932129.1 - - - figure legend:Fig 1, 2, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/12/11 2020/01/08 rogid:XMgolOCfVGpW7uGOTIAmqAIaK1c8364 rogid:XMgolOCfVGpW7uGOTIAmqAIaK1c8364 rigid:Zp7aSvIRzP6oxydWz1UmLa4TmvE false binding-associated region:133-797|mutation:647-647 binding-associated region:133-797|mutation:647-647 4 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:A0A6I8RQZ3 uniprotkb:A0A6I8RQZ3 intact:EBI-25339071|ensembl:ENSXETP00000087439 intact:EBI-25339071|ensembl:ENSXETP00000087439 psi-mi:a0a6i8rqz3_xentr(display_long)|uniprotkb:trpv4(gene name)|psi-mi:trpv4(display_short) psi-mi:a0a6i8rqz3_xentr(display_long)|uniprotkb:trpv4(gene name)|psi-mi:trpv4(display_short) psi-mi:"MI:0114"(x-ray crystallography) Deng et al. (2018) pubmed:29483651|imex:IM-26824 taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)") taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21005615|imex:IM-26824-3|wwpdb:6C8F|wwpdb:6C8G|wwpdb:6C8H - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSXETG00000018609(gene)|go:"GO:0005216"(ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0098703"(calcium ion import across plasma membrane)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR008348(Vanilloid receptor 2)|interpro:IPR020683|interpro:IPR024862|interpro:IPR036770|ensembl:ENSXETT00000086064(transcript)|uniprotkb:A0A5G3JN24(uniprot-removed-ac)|refseq:XP_002932129.1 ensembl:ENSXETG00000018609(gene)|go:"GO:0005216"(ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0098703"(calcium ion import across plasma membrane)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR008348(Vanilloid receptor 2)|interpro:IPR020683|interpro:IPR024862|interpro:IPR036770|ensembl:ENSXETT00000086064(transcript)|uniprotkb:A0A5G3JN24(uniprot-removed-ac)|refseq:XP_002932129.1 - - - figure legend:Fig 1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/12/11 2020/01/08 rogid:XMgolOCfVGpW7uGOTIAmqAIaK1c8364 rogid:XMgolOCfVGpW7uGOTIAmqAIaK1c8364 rigid:Zp7aSvIRzP6oxydWz1UmLa4TmvE false binding-associated region:133-797|mutation:647-647 binding-associated region:133-797|mutation:647-647 4 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)