#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16110 uniprotkb:Q61362 intact:EBI-3508325 intact:EBI-8392424|uniprotkb:Q8BKL8|uniprotkb:Q4FJW9|intact:MINT-4090719|uniprotkb:Q99J84|uniprotkb:B0FEU7|uniprotkb:D3Z2P2|uniprotkb:Q3U291|ensembl:ENSMUSP00000080717 psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:ch3l1_mouse(display_long)|uniprotkb:Breast regression protein 39(gene name synonym)|uniprotkb:Chil1(gene name synonym)|uniprotkb:Chi3l1(gene name)|psi-mi:Chi3l1(display_short)|uniprotkb:Brp39(gene name synonym)|uniprotkb:Cartilage glycoprotein 39(gene name synonym)|uniprotkb:BRP39 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20260767|imex:IM-26395-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 refseq:NP_031721.2|refseq:XP_006529174.1|ensembl:ENSMUSG00000064246(gene)|ensembl:ENSMUST00000082060(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006032"(chitin catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008061"(chitin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0030324"(lung development)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR011583(Chitinase II)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028538|interpro:IPR029070|mint:Q61362|rcsb pdb:5XEP|reactome:R-MMU-6798695 - - comment:mint|function:May play an important role in the capacity of cells to respond to and cope with changes in their environment. May play a role in tissue remodeling and defense against pathogens figure legend:Figure 8 A/C|agonist:IL13-P20109|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-lung)|taxid:10090(Mus musculus) - 2018/03/22 2018/05/02 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rogid:vfTEjvey7dOkQXYuh+FeLLDMa3w10090 rigid:lQ8AB+ahm+PHJbx0nlniFalZnvE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P16110 uniprotkb:O88786 intact:EBI-3508325 intact:EBI-20260800|uniprotkb:A3F812|uniprotkb:Q3V2V5|ensembl:ENSMUSP00000033646|ensembl:ENSMUSP00000108446 psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:i13r2_mouse(display_long)|uniprotkb:Il13ra2(gene name)|psi-mi:Il13ra2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20260767|imex:IM-26395-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 refseq:NP_001292988.1|refseq:NP_032382.1|refseq:XP_006528770.1|refseq:XP_006528771.1|refseq:XP_017173884.1|ensembl:ENSMUSG00000031289(gene)|ensembl:ENSMUST00000033646(transcript)|ensembl:ENSMUST00000112827(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116 - - - figure legend:Figure 8 A/C|agonist:IL13-P20109|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-lung)|taxid:10090(Mus musculus) - 2018/03/22 2018/05/02 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rogid:ej6FDiQbxIRW5n9HtOfI5KBXEB410090 rigid:lQ8AB+ahm+PHJbx0nlniFalZnvE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88786 uniprotkb:P16110 intact:EBI-20260800|uniprotkb:A3F812|uniprotkb:Q3V2V5|ensembl:ENSMUSP00000033646|ensembl:ENSMUSP00000108446 intact:EBI-3508325 psi-mi:i13r2_mouse(display_long)|uniprotkb:Il13ra2(gene name)|psi-mi:Il13ra2(display_short) psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20260835|imex:IM-26395-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001292988.1|refseq:NP_032382.1|refseq:XP_006528770.1|refseq:XP_006528771.1|refseq:XP_017173884.1|ensembl:ENSMUSG00000031289(gene)|ensembl:ENSMUST00000033646(transcript)|ensembl:ENSMUST00000112827(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116 go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 - - - figure legend:Figure 8Ai|agonist:IL13-P20109|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-lung)|taxid:10090(Mus musculus) - 2018/03/22 2018/05/02 rogid:ej6FDiQbxIRW5n9HtOfI5KBXEB410090 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rigid:fDpQLmuhlLEY9egzn9EqIzPWVfQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q61362 uniprotkb:P16110 intact:EBI-8392424|uniprotkb:Q8BKL8|uniprotkb:Q4FJW9|intact:MINT-4090719|uniprotkb:Q99J84|uniprotkb:B0FEU7|uniprotkb:D3Z2P2|uniprotkb:Q3U291|ensembl:ENSMUSP00000080717 intact:EBI-3508325 psi-mi:ch3l1_mouse(display_long)|uniprotkb:Breast regression protein 39(gene name synonym)|uniprotkb:Chil1(gene name synonym)|uniprotkb:Chi3l1(gene name)|psi-mi:Chi3l1(display_short)|uniprotkb:Brp39(gene name synonym)|uniprotkb:Cartilage glycoprotein 39(gene name synonym)|uniprotkb:BRP39 protein(gene name synonym) psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20261231|imex:IM-26395-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031721.2|refseq:XP_006529174.1|ensembl:ENSMUSG00000064246(gene)|ensembl:ENSMUST00000082060(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006032"(chitin catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008061"(chitin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0030324"(lung development)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR011583(Chitinase II)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028538|interpro:IPR029070|mint:Q61362|rcsb pdb:5XEP|reactome:R-MMU-6798695 go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 - comment:mint|function:May play an important role in the capacity of cells to respond to and cope with changes in their environment. May play a role in tissue remodeling and defense against pathogens - figure legend:Figure 8C|agonist:IL13-P20109|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-lung)|taxid:10090(Mus musculus) - 2018/03/22 2018/05/02 rogid:vfTEjvey7dOkQXYuh+FeLLDMa3w10090 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rigid:pfdYIv2Z1Qw/xrkfelk+8Br32KQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36222 uniprotkb:P17931 intact:EBI-6917454|ensembl:ENSP00000255409|uniprotkb:B2R7B0|uniprotkb:P30923|uniprotkb:Q8IVA4|uniprotkb:Q96HI7 intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301 psi-mi:ch3l1_human(display_long)|uniprotkb:CHI3L1(gene name)|psi-mi:CHI3L1(display_short)|uniprotkb:39 kDa synovial protein(gene name synonym)|uniprotkb:Cartilage glycoprotein 39(gene name synonym)|uniprotkb:YKL-40(gene name synonym) psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20260956|imex:IM-26395-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000133048(gene)|ensembl:ENST00000255409(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006032"(chitin catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008061"(chitin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051216"(cartilage development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR011583(Chitinase II)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028538|interpro:IPR029070|rcsb pdb:1HJV|rcsb pdb:1HJW|rcsb pdb:1HJX|rcsb pdb:1LA7|rcsb pdb:1NWR|rcsb pdb:1NWS|rcsb pdb:1NWT|reactome:R-HSA-6798695|rcsb pdb:1NWU|refseq:NP_001267.2 refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N - - - figure legend:Figure 8B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2018/03/22 2018/05/02 rogid:zZfR9p8Rzm74r9jur2r1nUoBR4M9606 rogid:5FijxEN6irEGIg4AtAdn6DB03e49606 rigid:w2SLjHzSdRI6vIIbUwkqA20mVO4 false - myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P36222 uniprotkb:P17931 intact:EBI-6917454|ensembl:ENSP00000255409|uniprotkb:B2R7B0|uniprotkb:P30923|uniprotkb:Q8IVA4|uniprotkb:Q96HI7 intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301 psi-mi:ch3l1_human(display_long)|uniprotkb:CHI3L1(gene name)|psi-mi:CHI3L1(display_short)|uniprotkb:39 kDa synovial protein(gene name synonym)|uniprotkb:Cartilage glycoprotein 39(gene name synonym)|uniprotkb:YKL-40(gene name synonym) psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20261112|imex:IM-26395-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000133048(gene)|ensembl:ENST00000255409(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006032"(chitin catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008061"(chitin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051216"(cartilage development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR011583(Chitinase II)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028538|interpro:IPR029070|rcsb pdb:1HJV|rcsb pdb:1HJW|rcsb pdb:1HJX|rcsb pdb:1LA7|rcsb pdb:1NWR|rcsb pdb:1NWS|rcsb pdb:1NWT|reactome:R-HSA-6798695|rcsb pdb:1NWU|refseq:NP_001267.2 refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N - - - figure legend:Figure 8Bi|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2018/03/22 2018/05/02 rogid:zZfR9p8Rzm74r9jur2r1nUoBR4M9606 rogid:5FijxEN6irEGIg4AtAdn6DB03e49606 rigid:w2SLjHzSdRI6vIIbUwkqA20mVO4 false - myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q61362 uniprotkb:P16110 intact:EBI-8392424|uniprotkb:Q8BKL8|uniprotkb:Q4FJW9|intact:MINT-4090719|uniprotkb:Q99J84|uniprotkb:B0FEU7|uniprotkb:D3Z2P2|uniprotkb:Q3U291|ensembl:ENSMUSP00000080717 intact:EBI-3508325 psi-mi:ch3l1_mouse(display_long)|uniprotkb:Breast regression protein 39(gene name synonym)|uniprotkb:Chil1(gene name synonym)|uniprotkb:Chi3l1(gene name)|psi-mi:Chi3l1(display_short)|uniprotkb:Brp39(gene name synonym)|uniprotkb:Cartilage glycoprotein 39(gene name synonym)|uniprotkb:BRP39 protein(gene name synonym) psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-20262170|imex:IM-26395-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031721.2|refseq:XP_006529174.1|ensembl:ENSMUSG00000064246(gene)|ensembl:ENSMUST00000082060(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006032"(chitin catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008061"(chitin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0030324"(lung development)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR011583(Chitinase II)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028538|interpro:IPR029070|mint:Q61362|rcsb pdb:5XEP|reactome:R-MMU-6798695 go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus) comment:mint|function:May play an important role in the capacity of cells to respond to and cope with changes in their environment. May play a role in tissue remodeling and defense against pathogens - figure legend:Figure 8D|comment:Gal-3 and CHI3L1 were similarly expressed in the cytoplasm and to a lesser degree in the nuclei of the lung cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-lung)|taxid:10090(Mus musculus) - 2018/03/22 2018/05/02 rogid:vfTEjvey7dOkQXYuh+FeLLDMa3w10090 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rigid:pfdYIv2Z1Qw/xrkfelk+8Br32KQ false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q61362 uniprotkb:P16110 intact:EBI-8392424|uniprotkb:Q8BKL8|uniprotkb:Q4FJW9|intact:MINT-4090719|uniprotkb:Q99J84|uniprotkb:B0FEU7|uniprotkb:D3Z2P2|uniprotkb:Q3U291|ensembl:ENSMUSP00000080717 intact:EBI-3508325 psi-mi:ch3l1_mouse(display_long)|uniprotkb:Breast regression protein 39(gene name synonym)|uniprotkb:Chil1(gene name synonym)|uniprotkb:Chi3l1(gene name)|psi-mi:Chi3l1(display_short)|uniprotkb:Brp39(gene name synonym)|uniprotkb:Cartilage glycoprotein 39(gene name synonym)|uniprotkb:BRP39 protein(gene name synonym) psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-20263122|imex:IM-26395-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031721.2|refseq:XP_006529174.1|ensembl:ENSMUSG00000064246(gene)|ensembl:ENSMUST00000082060(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006032"(chitin catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008061"(chitin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0030324"(lung development)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR011583(Chitinase II)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028538|interpro:IPR029070|mint:Q61362|rcsb pdb:5XEP|reactome:R-MMU-6798695 go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus) comment:mint|function:May play an important role in the capacity of cells to respond to and cope with changes in their environment. May play a role in tissue remodeling and defense against pathogens - figure legend:Figure 8E|comment:Gal-3 and CHI3L1 were similarly expressed in the cytoplasm and to a lesser degree in the nuclei of the lung cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-pam)|taxid:10090(mouse pam) - 2018/03/22 2018/05/02 rogid:vfTEjvey7dOkQXYuh+FeLLDMa3w10090 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rigid:pfdYIv2Z1Qw/xrkfelk+8Br32KQ false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P36222-PRO_0000011965 uniprotkb:P17931 intact:EBI-15187802 intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301 psi-mi:p36222-pro_0000011965(display_long)|uniprotkb:39 kDa synovial protein(gene name synonym)|uniprotkb:Cartilage glycoprotein 39(gene name synonym)|uniprotkb:YKL-40(gene name synonym)|uniprotkb:CHI3L1(gene name)|psi-mi:CHI3L1(display_short) psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-20263252|imex:IM-26395-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6917454(chain-parent) refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N - chain-seq-start:22|chain-seq-end:383 - figure legend:figure 9A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/03/22 2018/05/02 rogid:eHqLnIQu7kfYBbTud2ix0agXLwQ9606 rogid:5FijxEN6irEGIg4AtAdn6DB03e49606 rigid:nxhlHEn1Q4I3Nv2SIpBgYLZlpqQ false his tag:c-c his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14627 uniprotkb:P17931 intact:EBI-4320063|uniprotkb:A8K7E2|uniprotkb:O00667|ensembl:ENSP00000243213|ensembl:ENSP00000361004 intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301 psi-mi:i13r2_human(display_long)|uniprotkb:IL13RA2(gene name)|psi-mi:IL13RA2(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:Interleukin-13-binding protein(gene name synonym) psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20263361|imex:IM-26395-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000631.1|ensembl:ENSG00000123496(gene)|ensembl:ENST00000243213(transcript)|ensembl:ENST00000371936(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:3LB6|reactome:R-HSA-6785807|dip:DIP-3340N refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N - - - figure legend:figure 9B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/03/22 2018/05/15 rogid:LItbTlLuFXGhjC4PVCIW9aeBRZk9606 rogid:5FijxEN6irEGIg4AtAdn6DB03e49606 rigid:c7wDx60wU1BxOFW36cYeGS0XKLE false fc-igg tag:c-c|sufficient binding region:27-343 his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14627 uniprotkb:P17931 intact:EBI-4320063|uniprotkb:A8K7E2|uniprotkb:O00667|ensembl:ENSP00000243213|ensembl:ENSP00000361004 intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301 psi-mi:i13r2_human(display_long)|uniprotkb:IL13RA2(gene name)|psi-mi:IL13RA2(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:Interleukin-13-binding protein(gene name synonym) psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20263459|imex:IM-26395-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000631.1|ensembl:ENSG00000123496(gene)|ensembl:ENST00000243213(transcript)|ensembl:ENST00000371936(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:3LB6|reactome:R-HSA-6785807|dip:DIP-3340N refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N - - - figure legend:figure 9C-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/03/22 2018/05/15 rogid:LItbTlLuFXGhjC4PVCIW9aeBRZk9606 rogid:5FijxEN6irEGIg4AtAdn6DB03e49606 rigid:dggT05FI//x3G75YrqT8so+zWH8 false fc-igg tag:c-c|sufficient binding region:27-343 his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14627 uniprotkb:Q86XT9 intact:EBI-4320063|uniprotkb:A8K7E2|uniprotkb:O00667|ensembl:ENSP00000243213|ensembl:ENSP00000361004 intact:EBI-20264080|uniprotkb:D5FK14|uniprotkb:Q8WVV8|ensembl:ENSP00000279396|ensembl:ENSP00000388485|ensembl:ENSP00000456960|ensembl:ENSP00000457492|ensembl:ENSP00000459813 psi-mi:i13r2_human(display_long)|uniprotkb:IL13RA2(gene name)|psi-mi:IL13RA2(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:Interleukin-13-binding protein(gene name synonym) psi-mi:tm219_human(display_long)|uniprotkb:TMEM219(gene name)|psi-mi:TMEM219(display_short)|uniprotkb:Transmembrane protein 219(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20263459|imex:IM-26395-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000631.1|ensembl:ENSG00000123496(gene)|ensembl:ENST00000243213(transcript)|ensembl:ENST00000371936(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:3LB6|reactome:R-HSA-6785807|dip:DIP-3340N refseq:NP_001077082.1|refseq:NP_919256.1|refseq:XP_005255180.1|ensembl:ENSG00000149932(gene)|ensembl:ENST00000279396(transcript)|ensembl:ENST00000414689(transcript)|ensembl:ENST00000561899(transcript)|ensembl:ENST00000566848(transcript)|ensembl:ENST00000570255(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR039493|interpro:IPR039587|reactome:R-HSA-6803211 - - - figure legend:figure 9C-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/03/22 2018/05/15 rogid:LItbTlLuFXGhjC4PVCIW9aeBRZk9606 rogid:JDeHxM/rrToXnR49YkzrDeu2ono9606 rigid:dggT05FI//x3G75YrqT8so+zWH8 false fc-igg tag:c-c|sufficient binding region:27-343 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14627 uniprotkb:Q86XT9 intact:EBI-4320063|uniprotkb:A8K7E2|uniprotkb:O00667|ensembl:ENSP00000243213|ensembl:ENSP00000361004 intact:EBI-20264080|uniprotkb:D5FK14|uniprotkb:Q8WVV8|ensembl:ENSP00000279396|ensembl:ENSP00000388485|ensembl:ENSP00000456960|ensembl:ENSP00000457492|ensembl:ENSP00000459813 psi-mi:i13r2_human(display_long)|uniprotkb:IL13RA2(gene name)|psi-mi:IL13RA2(display_short)|uniprotkb:IL13R(gene name synonym)|uniprotkb:Interleukin-13-binding protein(gene name synonym) psi-mi:tm219_human(display_long)|uniprotkb:TMEM219(gene name)|psi-mi:TMEM219(display_short)|uniprotkb:Transmembrane protein 219(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhou et al. (2018) pubmed:29427412|imex:IM-26395 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20264124|imex:IM-26395-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000631.1|ensembl:ENSG00000123496(gene)|ensembl:ENST00000243213(transcript)|ensembl:ENST00000371936(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043305"(negative regulation of mast cell degranulation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:3LB6|reactome:R-HSA-6785807|dip:DIP-3340N refseq:NP_001077082.1|refseq:NP_919256.1|refseq:XP_005255180.1|ensembl:ENSG00000149932(gene)|ensembl:ENST00000279396(transcript)|ensembl:ENST00000414689(transcript)|ensembl:ENST00000561899(transcript)|ensembl:ENST00000566848(transcript)|ensembl:ENST00000570255(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR039493|interpro:IPR039587|reactome:R-HSA-6803211 - - - figure legend:figure 9C-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/03/22 2018/05/15 rogid:LItbTlLuFXGhjC4PVCIW9aeBRZk9606 rogid:JDeHxM/rrToXnR49YkzrDeu2ono9606 rigid:lKrvMctbn4mqqiWcZltUB5YdTjM false fc-igg tag:c-c|sufficient binding region:27-343 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)