#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q3KP66	uniprotkb:Q15438	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-997830|uniprotkb:Q9P123|uniprotkb:Q9P124|uniprotkb:A6NFW7|ensembl:ENSP00000354398|ensembl:ENSP00000389095|uniprotkb:B7Z1T4	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:cyh1_human(display_long)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:SEC7 homolog B2-1(gene name synonym)|uniprotkb:CYTH1(gene name)|psi-mi:CYTH1(display_short)|uniprotkb:D17S811E(gene name synonym)|uniprotkb:PSCD1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_004753.1|refseq:NP_059430.2|refseq:NP_001278947.1|refseq:NP_001278948.1|refseq:XP_011523779.1|ensembl:ENSG00000108669(gene)|ensembl:ENST00000361101(transcript)|ensembl:ENST00000446868(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|mint:Q15438|rcsb pdb:1BC9|rcsb pdb:4A4P|reactome:R-HSA-6811438	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:0LBGFE+FqugOIhROMnJaFcEGyks9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q15843	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-716247|uniprotkb:Q3SXN8|uniprotkb:Q6LES6|ensembl:ENSP00000250495|ensembl:ENSP00000496420	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:nedd8_human(display_long)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 8(gene name synonym)|uniprotkb:NEDD8(gene name)|psi-mi:NEDD8(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_006147.1|ensembl:ENSG00000129559(gene)|ensembl:ENSG00000285246(gene)|ensembl:ENST00000250495(transcript)|ensembl:ENST00000643069(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008104"(protein localization)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|mint:Q15843|rcsb pdb:1NDD|rcsb pdb:1R4M|rcsb pdb:1R4N|rcsb pdb:1XT9|rcsb pdb:2BKR|rcsb pdb:2KO3|rcsb pdb:2N7K|rcsb pdb:2NVU|rcsb pdb:3DBH|rcsb pdb:3DBL|rcsb pdb:3DBR|rcsb pdb:3DQV|rcsb pdb:3GZN|rcsb pdb:4F8C|rcsb pdb:4FBJ|rcsb pdb:4HCP|rcsb pdb:4P5O|rcsb pdb:6R7F|rcsb pdb:6R7I|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-2173789|reactome:R-HSA-5689603|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-917937|dip:DIP-29266N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:qB1KNoIOwa1ONfphWDWjJri9hwE9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q02878	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q92901	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-2514377|ensembl:ENSP00000268661	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:rl3l_human(display_long)|uniprotkb:RPL3L(gene name)|psi-mi:RPL3L(display_short)|uniprotkb:Large ribosomal subunit protein uL3-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	ensembl:ENSG00000140986(gene)|ensembl:ENST00000268661(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_005052.1|ensembl:ENSP00000268661	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:hG1wpRH7DNIbNB4zCONsF22W3zc9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P62280	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:O95271	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-1105254|uniprotkb:O95272|uniprotkb:Q4G0F2|intact:EBI-28985643|ensembl:ENSP00000311579	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:tnks1_human(display_long)|uniprotkb:TNKS(gene name)|psi-mi:TNKS(display_short)|uniprotkb:PARP5A(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:TIN1(gene name synonym)|uniprotkb:TINF1(gene name synonym)|uniprotkb:TNKS1(gene name synonym)|uniprotkb:Tankyrase I(gene name synonym)|uniprotkb:TNKS-1(gene name synonym)|uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 5A(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 5(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-1(gene name synonym)|uniprotkb:Tankyrase-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_003738.2|rcsb pdb:5JHQ|rcsb pdb:5JTI|rcsb pdb:5JU5|rcsb pdb:5KNI|rcsb pdb:6QXU|rcsb pdb:6URQ|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5545619|reactome:R-HSA-5689880|reactome:R-HSA-8948751|rcsb pdb:5GP7|ensembl:ENSP00000311579|ensembl:ENSG00000173273(gene)|ensembl:ENST00000310430(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051028"(mRNA transport)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904743"(negative regulation of telomeric DNA binding)|go:"GO:1904908"(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR028731|interpro:IPR036770|mint:O95271|rcsb pdb:2RF5|rcsb pdb:3UDD|rcsb pdb:3UH2|rcsb pdb:3UH4|rcsb pdb:4DVI|rcsb pdb:4I9I|go:"GO:0016055"(Wnt signaling pathway)|rcsb pdb:4K4F|rcsb pdb:4KRS|rcsb pdb:4LI6|rcsb pdb:4LI7|rcsb pdb:4LI8|rcsb pdb:4MSG|rcsb pdb:4MSK|rcsb pdb:4MT9|rcsb pdb:4N3R|rcsb pdb:4N4V|rcsb pdb:4OA7|rcsb pdb:4TOR|rcsb pdb:4TOS|rcsb pdb:4U6A|rcsb pdb:4UUH|rcsb pdb:4UW1|rcsb pdb:4K4E|rcsb pdb:4W5S|rcsb pdb:4W6E|rcsb pdb:5EBT|rcsb pdb:5ECE|rcsb pdb:5ETY|dip:DIP-36652N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:0WKEfg5OMAISQutoJb2w+hBfmOU9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P46779	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-366357|uniprotkb:Q6IAY0|uniprotkb:Q96FX1|uniprotkb:Q9BWQ0|uniprotkb:B2R4A6|uniprotkb:B4DEP9|uniprotkb:E9PB24|uniprotkb:C9JB50|uniprotkb:G5E9L2|ensembl:ENSP00000342787|ensembl:ENSP00000453319	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:rl28_human(display_long)|uniprotkb:RPL28(gene name)|psi-mi:RPL28(display_short)|uniprotkb:Large ribosomal subunit protein eL28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_001129608.1|refseq:NP_001129609.1|refseq:NP_000982.2|refseq:NP_001129606.1|refseq:NP_001129607.1|ensembl:ENSG00000108107(gene)|ensembl:ENST00000344063(transcript)|ensembl:ENST00000559463(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002672(Ribosomal protein L28e)|interpro:IPR029004|mint:P46779|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:I7Me1zjfxk98g6C2NoYOWlmrYVc9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P27635	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q07020	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-352694|intact:EBI-8456577|intact:MINT-8429255|uniprotkb:F8VWC5|uniprotkb:Q8WTZ6|ensembl:ENSP00000447001	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:rl18_human(display_long)|uniprotkb:RPL18(gene name)|psi-mi:RPL18(display_short)|uniprotkb:Large ribosomal subunit protein eL18(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_000970.1|ensembl:ENSG00000063177(gene)|ensembl:ENST00000549920(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000039(Ribosomal protein L18e)|interpro:IPR021131|interpro:IPR021132|interpro:IPR036227|mint:Q07020|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001257419.1	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:GgzBcLEQgBqbApFlaQIU2jktkAE9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P51116	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P62877	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-398523|uniprotkb:Q8N6Z8|uniprotkb:Q9D1S2|uniprotkb:Q9WUK9|uniprotkb:Q9Y254|uniprotkb:B2RDY1|ensembl:ENSP00000216225	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:rbx1_human(display_long)|uniprotkb:RBX1(gene name)|psi-mi:RBX1(display_short)|uniprotkb:RNF75(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins 1(gene name synonym)|uniprotkb:RING finger protein 75(gene name synonym)|uniprotkb:Protein ZYP(gene name synonym)|uniprotkb:RING-box protein 1(gene name synonym)|uniprotkb:E3 ubiquitin-protein transferase RBX1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_055063.1|dip:DIP-17014N|ensembl:ENSG00000100387(gene)|ensembl:ENST00000216225(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|mint:P62877|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:2HYE|rcsb pdb:2LGV|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:3RTR|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-110314|reactome:R-HSA-1170546|reactome:R-HSA-1234176|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2894862|reactome:R-HSA-4641258|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68949|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:pSaSNRZo+QudTPXOLUlksOj3smM9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q9NVI7	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:IZKJEVLLS/DFINgBgO5frizN1P49606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q06787	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-366305|ensembl:ENSP00000359506|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X mental retardation protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	ensembl:ENSG00000102081(gene)|ensembl:ENST00000370475(transcript)|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990812"(growth cone filopodium)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|dip:DIP-29509N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:+iN/J/MbxTcRwgDezYseEDwLep49606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P62753	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:beDuXCIqL99V9JlVfpzx7MdpH689606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q13616	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P62241	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-351811|uniprotkb:Q6IRL7|uniprotkb:P09058|ensembl:ENSP00000379888	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:rs8_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:Small ribosomal subunit protein eS8(gene name synonym)|uniprotkb:OK/SW-cl.83(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_001003.1|ensembl:ENSG00000142937(gene)|ensembl:ENST00000396651(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62241|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:6G5H|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975957|reactome:R-HSA-975956	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P51114	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000114416(gene)|ensembl:ENST00000357559(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|go:"GO:0014069"(postsynaptic density)|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|mint:P51114|dip:DIP-40789N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q5SW79	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q9Y297	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-307461|uniprotkb:Q9Y213|uniprotkb:B5MD49|uniprotkb:Q5W142|ensembl:ENSP00000359206|uniprotkb:Q5W141	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:fbw1a_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:BTRCP(gene name synonym)|uniprotkb:FBW1A(gene name synonym)|uniprotkb:FBXW1A(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)|uniprotkb:E3RSIkappaB(gene name synonym)|uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)|uniprotkb:Epididymis tissue protein Li 2a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_003930.1|refseq:NP_378663.1|ensembl:ENSG00000166167(gene)|ensembl:ENST00000370187(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|interpro:IPR021977|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR036047|interpro:IPR036322|mint:Q9Y297|rcsb pdb:1P22|rcsb pdb:2P64|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6TTU|reactome:R-HSA-1169091|reactome:R-HSA-1170546|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-195253|reactome:R-HSA-202424|go:"GO:0051726"(regulation of cell cycle)|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-3769402|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-983168|dip:DIP-31607N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:9/bXDY6YvJWvP6iMSgOPT9CNGAE9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q99418	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-448974|intact:EBI-1760516|uniprotkb:Q8IXY9|uniprotkb:Q92958|intact:EBI-1965579|uniprotkb:A8K8P0|ensembl:ENSP00000493357	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:cyh2_human(display_long)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 2(gene name synonym)|uniprotkb:ARF nucleotide-binding site opener(gene name synonym)|uniprotkb:ARF exchange factor(gene name synonym)|uniprotkb:CYTH2(gene name)|psi-mi:CYTH2(display_short)|uniprotkb:ARNO(gene name synonym)|uniprotkb:PSCD2L(gene name synonym)|uniprotkb:PSCD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_004219.3|refseq:NP_059431.1|dip:DIP-31598N|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|mint:Q99418|rcsb pdb:1PBV|rcsb pdb:1R8M|rcsb pdb:1R8Q|rcsb pdb:1R8S|rcsb pdb:1S9D|rcsb pdb:4JMI|rcsb pdb:4JMO|rcsb pdb:4JWL|rcsb pdb:4JXH|rcsb pdb:4L5M|rcsb pdb:4Z21|reactome:R-HSA-6811438|ensembl:ENSG00000105443(gene)|ensembl:ENST00000641098(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:wGF6f2/B1HkGHOB/juI9LS1N/ww9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q96ES7	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:O43739	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-741648|uniprotkb:A4D2N8|ensembl:ENSP00000379967	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:cyh3_human(display_long)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 3(gene name synonym)|uniprotkb:ARF nucleotide-binding site opener 3(gene name synonym)|uniprotkb:General receptor of phosphoinositides 1(gene name synonym)|uniprotkb:CYTH3(gene name)|psi-mi:CYTH3(display_short)|uniprotkb:ARNO3(gene name synonym)|uniprotkb:GRP1(gene name synonym)|uniprotkb:PSCD3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_004218.1|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|rcsb pdb:4KAX|rcsb pdb:6U3E|rcsb pdb:6U3G|reactome:R-HSA-6811438|ensembl:ENSG00000008256(gene)|ensembl:ENST00000396741(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|dip:DIP-60444N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:QLicgFt7zvL4QcS1DKGM0ioegoI9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P27797	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:P63208	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q3KP66	uniprotkb:Q9UKB1	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-355189|uniprotkb:Q9P2S8|uniprotkb:Q9P2S9|uniprotkb:Q9Y4C6|uniprotkb:B2RC98|ensembl:ENSP00000265094	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:fbw1b_human(display_long)|uniprotkb:KIAA0696(gene name synonym)|uniprotkb:FBXW11(gene name)|psi-mi:FBXW11(display_short)|uniprotkb:BTRCP2(gene name synonym)|uniprotkb:FBW1B(gene name synonym)|uniprotkb:FBXW1B(gene name synonym)|uniprotkb:F-box/WD repeat-containing protein 1B(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP2(gene name synonym)|uniprotkb:Homologous to Slimb protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20715953|imex:IM-26716-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_036432.2|refseq:NP_387448.2|refseq:NP_387449.2|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007097"(nuclear migration)|go:"GO:0007281"(germ cell development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0005635"(nuclear envelope)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0070840"(dynein complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|mint:Q9UKB1|rcsb pdb:6WNX|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0048511"(rhythmic process)|ensembl:ENSG00000072803(gene)|ensembl:ENST00000265094(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|dip:DIP-27593N	-	comment:mint	-	figure legend:Fig 1B, Table S1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:8wLc2Pt+mLfRsNwXOnjho+1A0u09606	rigid:bsXuamsefHY1pWcL89hVu8jXEBI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:Q15438	uniprotkb:Q3KP66	intact:EBI-997830|uniprotkb:Q9P123|uniprotkb:Q9P124|uniprotkb:A6NFW7|ensembl:ENSP00000354398|ensembl:ENSP00000389095|uniprotkb:B7Z1T4	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	psi-mi:cyh1_human(display_long)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:SEC7 homolog B2-1(gene name synonym)|uniprotkb:CYTH1(gene name)|psi-mi:CYTH1(display_short)|uniprotkb:D17S811E(gene name synonym)|uniprotkb:PSCD1(gene name synonym)	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20716016|imex:IM-26716-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004753.1|refseq:NP_059430.2|refseq:NP_001278947.1|refseq:NP_001278948.1|refseq:XP_011523779.1|ensembl:ENSG00000108669(gene)|ensembl:ENST00000361101(transcript)|ensembl:ENST00000446868(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|mint:Q15438|rcsb pdb:1BC9|rcsb pdb:4A4P|reactome:R-HSA-6811438	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	-	-	comment:mint	figure legend:Fig 1C|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:0LBGFE+FqugOIhROMnJaFcEGyks9606	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rigid:53m+w1XVl5ch8onlP7MnXNq+t5Q	false	flag tag:n-n|strep ii tag:n-n|sufficient binding region:1-68	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q3KP66	uniprotkb:Q99418	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-448974|intact:EBI-1760516|uniprotkb:Q8IXY9|uniprotkb:Q92958|intact:EBI-1965579|uniprotkb:A8K8P0|ensembl:ENSP00000493357	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:cyh2_human(display_long)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 2(gene name synonym)|uniprotkb:ARF nucleotide-binding site opener(gene name synonym)|uniprotkb:ARF exchange factor(gene name synonym)|uniprotkb:CYTH2(gene name)|psi-mi:CYTH2(display_short)|uniprotkb:ARNO(gene name synonym)|uniprotkb:PSCD2L(gene name synonym)|uniprotkb:PSCD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20716058|imex:IM-26716-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_004219.3|refseq:NP_059431.1|dip:DIP-31598N|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|mint:Q99418|rcsb pdb:1PBV|rcsb pdb:1R8M|rcsb pdb:1R8Q|rcsb pdb:1R8S|rcsb pdb:1S9D|rcsb pdb:4JMI|rcsb pdb:4JMO|rcsb pdb:4JWL|rcsb pdb:4JXH|rcsb pdb:4L5M|rcsb pdb:4Z21|reactome:R-HSA-6811438|ensembl:ENSG00000105443(gene)|ensembl:ENST00000641098(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)	-	comment:mint	-	figure legend:Fig S1E|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:wGF6f2/B1HkGHOB/juI9LS1N/ww9606	rigid:/nWJORo5+zsw7qXKfE9dZ/6LmwY	false	-	strep ii tag:n-n|flag tag:n-n|sufficient binding region:1-71	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15438	uniprotkb:Q3KP66	intact:EBI-997830|uniprotkb:Q9P123|uniprotkb:Q9P124|uniprotkb:A6NFW7|ensembl:ENSP00000354398|ensembl:ENSP00000389095|uniprotkb:B7Z1T4	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	psi-mi:cyh1_human(display_long)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:SEC7 homolog B2-1(gene name synonym)|uniprotkb:CYTH1(gene name)|psi-mi:CYTH1(display_short)|uniprotkb:D17S811E(gene name synonym)|uniprotkb:PSCD1(gene name synonym)	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20716070|imex:IM-26716-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004753.1|refseq:NP_059430.2|refseq:NP_001278947.1|refseq:NP_001278948.1|refseq:XP_011523779.1|ensembl:ENSG00000108669(gene)|ensembl:ENST00000361101(transcript)|ensembl:ENST00000446868(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|mint:Q15438|rcsb pdb:1BC9|rcsb pdb:4A4P|reactome:R-HSA-6811438	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	-	-	comment:mint	figure legend:Fig 1E|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:0LBGFE+FqugOIhROMnJaFcEGyks9606	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rigid:53m+w1XVl5ch8onlP7MnXNq+t5Q	false	ha tag:n-n	flag tag:n-n|strep ii tag:n-n|sufficient binding region:1-394	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q3KP66	uniprotkb:Q9Y297	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-307461|uniprotkb:Q9Y213|uniprotkb:B5MD49|uniprotkb:Q5W142|ensembl:ENSP00000359206|uniprotkb:Q5W141	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:fbw1a_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:BTRCP(gene name synonym)|uniprotkb:FBW1A(gene name synonym)|uniprotkb:FBXW1A(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)|uniprotkb:E3RSIkappaB(gene name synonym)|uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)|uniprotkb:Epididymis tissue protein Li 2a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20716118|imex:IM-26716-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_003930.1|refseq:NP_378663.1|ensembl:ENSG00000166167(gene)|ensembl:ENST00000370187(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|interpro:IPR021977|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR036047|interpro:IPR036322|mint:Q9Y297|rcsb pdb:1P22|rcsb pdb:2P64|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6TTU|reactome:R-HSA-1169091|reactome:R-HSA-1170546|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-195253|reactome:R-HSA-202424|go:"GO:0051726"(regulation of cell cycle)|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-3769402|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-983168|dip:DIP-31607N	-	comment:mint	-	figure legend:Fig 2C|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:9/bXDY6YvJWvP6iMSgOPT9CNGAE9606	rigid:mgrFCn+cxT1fWmS0ZhLAxP3lyIA	false	flag tag:n-n|strep ii tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q3KP66	uniprotkb:Q9UKB1	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	intact:EBI-355189|uniprotkb:Q9P2S8|uniprotkb:Q9P2S9|uniprotkb:Q9Y4C6|uniprotkb:B2RC98|ensembl:ENSP00000265094	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:fbw1b_human(display_long)|uniprotkb:KIAA0696(gene name synonym)|uniprotkb:FBXW11(gene name)|psi-mi:FBXW11(display_short)|uniprotkb:BTRCP2(gene name synonym)|uniprotkb:FBW1B(gene name synonym)|uniprotkb:FBXW1B(gene name synonym)|uniprotkb:F-box/WD repeat-containing protein 1B(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP2(gene name synonym)|uniprotkb:Homologous to Slimb protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20716128|imex:IM-26716-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	refseq:NP_036432.2|refseq:NP_387448.2|refseq:NP_387449.2|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007097"(nuclear migration)|go:"GO:0007281"(germ cell development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0005635"(nuclear envelope)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0070840"(dynein complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|mint:Q9UKB1|rcsb pdb:6WNX|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0048511"(rhythmic process)|ensembl:ENSG00000072803(gene)|ensembl:ENST00000265094(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|dip:DIP-27593N	-	comment:mint	-	figure legend:Fig 2D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rogid:8wLc2Pt+mLfRsNwXOnjho+1A0u09606	rigid:tyi2Oa845gOOnGdYxrZxukveGgs	false	strep ii tag:n-n|flag tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P62988	uniprotkb:Q15438-1	intact:EBI-8770560	intact:EBI-20716018|ensembl:ENSP00000354398|ensembl:ENSP00000389095	psi-mi:p62988(display_long)	psi-mi:q15438-1(display_long)|uniprotkb:CYTH1(gene name)|psi-mi:CYTH1(display_short)|uniprotkb:D17S811E(gene name synonym)|uniprotkb:PSCD1(gene name synonym)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:SEC7 homolog B2-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20716138|imex:IM-26716-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000108669(gene)|ensembl:ENST00000361101(transcript)|ensembl:ENST00000446868(transcript)|intact:EBI-997830(isoform-parent)	-	-	-	figure legend:Fig 2A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/03	-	rogid:0LBGFE+FqugOIhROMnJaFcEGyks9606	-	false	myc tag:n-n	flag tag:c-c|strep ii tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15438	uniprotkb:Q3KP66	intact:EBI-997830|uniprotkb:Q9P123|uniprotkb:Q9P124|uniprotkb:A6NFW7|ensembl:ENSP00000354398|ensembl:ENSP00000389095|uniprotkb:B7Z1T4	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	psi-mi:cyh1_human(display_long)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:SEC7 homolog B2-1(gene name synonym)|uniprotkb:CYTH1(gene name)|psi-mi:CYTH1(display_short)|uniprotkb:D17S811E(gene name synonym)|uniprotkb:PSCD1(gene name synonym)	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20716226|imex:IM-26716-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004753.1|refseq:NP_059430.2|refseq:NP_001278947.1|refseq:NP_001278948.1|refseq:XP_011523779.1|ensembl:ENSG00000108669(gene)|ensembl:ENST00000361101(transcript)|ensembl:ENST00000446868(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|mint:Q15438|rcsb pdb:1BC9|rcsb pdb:4A4P|reactome:R-HSA-6811438	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	-	-	comment:mint	figure legend:Fig 1E|comment:Increased expression of INAVA was sufficient to increase the levels of ubiquitinated cytohesin-1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/08/01	2018/08/30	rogid:0LBGFE+FqugOIhROMnJaFcEGyks9606	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rigid:53m+w1XVl5ch8onlP7MnXNq+t5Q	false	flag tag:n-n	strep ii tag:n-n|v5 tag:c-c|mutation increasing interaction:333-333	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15438	uniprotkb:Q3KP66	intact:EBI-997830|uniprotkb:Q9P123|uniprotkb:Q9P124|uniprotkb:A6NFW7|ensembl:ENSP00000354398|ensembl:ENSP00000389095|uniprotkb:B7Z1T4	intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311	psi-mi:cyh1_human(display_long)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:SEC7 homolog B2-1(gene name synonym)|uniprotkb:CYTH1(gene name)|psi-mi:CYTH1(display_short)|uniprotkb:D17S811E(gene name synonym)|uniprotkb:PSCD1(gene name synonym)	psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohanan et al. (2018)	imex:IM-26716|pubmed:29420262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20716045|imex:IM-26716-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004753.1|refseq:NP_059430.2|refseq:NP_001278947.1|refseq:NP_001278948.1|refseq:XP_011523779.1|ensembl:ENSG00000108669(gene)|ensembl:ENST00000361101(transcript)|ensembl:ENST00000446868(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|mint:Q15438|rcsb pdb:1BC9|rcsb pdb:4A4P|reactome:R-HSA-6811438	refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)	-	-	comment:mint	figure legend:Fig 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma)	-	2018/08/01	2018/08/03	rogid:0LBGFE+FqugOIhROMnJaFcEGyks9606	rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606	rigid:53m+w1XVl5ch8onlP7MnXNq+t5Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)