#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6ZN18	uniprotkb:O75530	intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3	intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834	psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short)	psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Kasinath et al. (2018)	pubmed:29348366|imex:IM-28398	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20621657|wwpdb:6C24|emdb:EMD-7335|emdb:EMD-7337|wwpdb:6C23|emdb:EMD-7334|imex:IM-28398-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N	refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421	-	-	-	figure legend:Fig 1, Fig S1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/07/11	2020/06/23	rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606	rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606	rigid:wKmNpXzFJKZOfCLS4A6IZ3oLy90	false	-	-	1	1	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:Q6ZN18	uniprotkb:Q15910	intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3	intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3	psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short)	psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short)	psi-mi:"MI:0410"(3D electron microscopy)	Kasinath et al. (2018)	pubmed:29348366|imex:IM-28398	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20621657|wwpdb:6C24|emdb:EMD-7335|emdb:EMD-7337|wwpdb:6C23|emdb:EMD-7334|imex:IM-28398-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N	refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N	-	-	-	figure legend:Fig 1, Fig S1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/07/11	2020/06/23	rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606	rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606	rigid:wKmNpXzFJKZOfCLS4A6IZ3oLy90	false	-	-	1	1	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:Q6ZN18	uniprotkb:Q92833	intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3	intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280	psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short)	psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Kasinath et al. (2018)	pubmed:29348366|imex:IM-28398	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20621657|wwpdb:6C24|emdb:EMD-7335|emdb:EMD-7337|wwpdb:6C23|emdb:EMD-7334|imex:IM-28398-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N	refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")	-	-	-	figure legend:Fig 1, Fig S1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/07/11	2020/06/23	rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606	rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606	rigid:wKmNpXzFJKZOfCLS4A6IZ3oLy90	false	-	binding-associated region:116-450	1	1	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q6ZN18	uniprotkb:Q92833	intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3	intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280	psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short)	psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Kasinath et al. (2018)	pubmed:29348366|imex:IM-28398	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20621657|wwpdb:6C24|emdb:EMD-7335|emdb:EMD-7337|wwpdb:6C23|emdb:EMD-7334|imex:IM-28398-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N	refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")	-	-	-	figure legend:Fig 1, Fig S1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/07/11	2020/06/23	rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606	rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606	rigid:wKmNpXzFJKZOfCLS4A6IZ3oLy90	false	-	binding-associated region:106-450	1	1	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:Q6ZN18	uniprotkb:Q09028	intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3	intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9	psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short)	psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Kasinath et al. (2018)	pubmed:29348366|imex:IM-28398	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20621657|wwpdb:6C24|emdb:EMD-7335|emdb:EMD-7337|wwpdb:6C23|emdb:EMD-7334|imex:IM-28398-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N	ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N	-	-	-	figure legend:Fig 1, Fig S1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/07/11	2020/06/23	rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606	rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606	rigid:wKmNpXzFJKZOfCLS4A6IZ3oLy90	false	-	-	1	1	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:Q6ZN18	uniprotkb:Q15022	intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3	intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578	psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short)	psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Kasinath et al. (2018)	pubmed:29348366|imex:IM-28398	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-20621657|wwpdb:6C24|emdb:EMD-7335|emdb:EMD-7337|wwpdb:6C23|emdb:EMD-7334|imex:IM-28398-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N	dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421	-	-	-	figure legend:Fig 1, Fig S1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/07/11	2020/06/23	rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606	rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606	rigid:wKmNpXzFJKZOfCLS4A6IZ3oLy90	false	-	-	1	1	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)