#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:E2JF22	uniprotkb:E2JF22	intact:EBI-9837938	intact:EBI-9837938	psi-mi:piez1_mouse(display_long)|uniprotkb:Piezo1(gene name)|psi-mi:Piezo1(display_short)|uniprotkb:Fam38a(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym)	psi-mi:piez1_mouse(display_long)|uniprotkb:Piezo1(gene name)|psi-mi:Piezo1(display_short)|uniprotkb:Fam38a(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Saotome et al. (2018)	pubmed:29261642|imex:IM-26869	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-21004662|imex:IM-26869-1|wwpdb:6BPZ|emdb:EMD-7128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59655N|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805|rcsb pdb:3JAC|rcsb pdb:4RAX|rcsb pdb:5Z10|rcsb pdb:6B3R|rcsb pdb:6BPZ|rcsb pdb:6LQI	dip:DIP-59655N|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805|rcsb pdb:3JAC|rcsb pdb:4RAX|rcsb pdb:5Z10|rcsb pdb:6B3R|rcsb pdb:6BPZ|rcsb pdb:6LQI	-	-	-	figure legend:Fig 1, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2018/12/11	2019/01/21	rogid:hdah8UO1NXUhBKy6tqyZOD22z+E10090	rogid:hdah8UO1NXUhBKy6tqyZOD22z+E10090	rigid:Fgbs1GhJsqm9h1Kxed9FkE2ZwwQ	false	binding-associated region:1137-2547	binding-associated region:1137-2547	3	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)