#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q04377	uniprotkb:P38111	intact:EBI-35652|uniprotkb:D6VTC1|ensemblfungi:YDR499W	intact:EBI-6668|uniprotkb:Q02580|uniprotkb:D6VQD2|ensemblfungi:YBR136W	psi-mi:lcd1_yeast(display_long)|uniprotkb:LCD1(gene name)|psi-mi:LCD1(display_short)|uniprotkb:Lethal, checkpoint-defective, DNA damage-sensitive protein 1(gene name synonym)|uniprotkb:DNA damage checkpoint protein 2(gene name synonym)|uniprotkb:YDR499W(locus name)|uniprotkb:DDC2(gene name synonym)|uniprotkb:PIE1(gene name synonym)	psi-mi:atr_yeast(display_long)|uniprotkb:Mitosis entry checkpoint protein 1(gene name synonym)|uniprotkb:ATR homolog(gene name synonym)|uniprotkb:MEC1(gene name)|psi-mi:MEC1(display_short)|uniprotkb:ESR1(gene name synonym)|uniprotkb:SAD3(gene name synonym)|uniprotkb:YBR136W(locus name)|uniprotkb:YBR1012(orf name)|uniprotkb:DNA-damage checkpoint kinase MEC1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Wang et al. (2017)	imex:IM-26773|pubmed:29191911	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-20596137|wwpdb:5X6O|emdb:EMD-6708|imex:IM-26773-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010787.3|sgd:S000002907|mint:Q04377|dip:DIP-2970N|ensemblfungi:YDR499W(gene)|ensemblfungi:YDR499W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0045184"(establishment of protein localization)|interpro:IPR018622|rcsb pdb:5OMD|rcsb pdb:5X6O|rcsb pdb:6Z2W|rcsb pdb:6Z2X|rcsb pdb:6Z3A	refseq:NP_009694.3|sgd:S000000340|dip:DIP-799N|mint:P38111|ensemblfungi:YBR136W(gene)|ensemblfungi:YBR136W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|rcsb pdb:5X6O|rcsb pdb:6Z2W|rcsb pdb:6Z2X|rcsb pdb:6Z3A	-	crc64:E981C1A38F3310BF	crc64:C06AEF9F0484A615	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/06/26	2018/06/27	rogid:qx0fM2HHwEI/GtbjRXu8kQrSp5w559292	rogid:BXSOV2x+FVvpAqOdHUGcYrTCN0A559292	rigid:QTC8BxVajulQ/dpgaph2wZf+dIY	false	-	flag tag:c-c	2	2	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q04377	uniprotkb:P38111	intact:EBI-35652|uniprotkb:D6VTC1|ensemblfungi:YDR499W	intact:EBI-6668|uniprotkb:Q02580|uniprotkb:D6VQD2|ensemblfungi:YBR136W	psi-mi:lcd1_yeast(display_long)|uniprotkb:LCD1(gene name)|psi-mi:LCD1(display_short)|uniprotkb:Lethal, checkpoint-defective, DNA damage-sensitive protein 1(gene name synonym)|uniprotkb:DNA damage checkpoint protein 2(gene name synonym)|uniprotkb:YDR499W(locus name)|uniprotkb:DDC2(gene name synonym)|uniprotkb:PIE1(gene name synonym)	psi-mi:atr_yeast(display_long)|uniprotkb:Mitosis entry checkpoint protein 1(gene name synonym)|uniprotkb:ATR homolog(gene name synonym)|uniprotkb:MEC1(gene name)|psi-mi:MEC1(display_short)|uniprotkb:ESR1(gene name synonym)|uniprotkb:SAD3(gene name synonym)|uniprotkb:YBR136W(locus name)|uniprotkb:YBR1012(orf name)|uniprotkb:DNA-damage checkpoint kinase MEC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2017)	imex:IM-26773|pubmed:29191911	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-20620894|imex:IM-26773-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010787.3|sgd:S000002907|mint:Q04377|dip:DIP-2970N|ensemblfungi:YDR499W(gene)|ensemblfungi:YDR499W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0045184"(establishment of protein localization)|interpro:IPR018622|rcsb pdb:5OMD|rcsb pdb:5X6O|rcsb pdb:6Z2W|rcsb pdb:6Z2X|rcsb pdb:6Z3A	refseq:NP_009694.3|sgd:S000000340|dip:DIP-799N|mint:P38111|ensemblfungi:YBR136W(gene)|ensemblfungi:YBR136W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|rcsb pdb:5X6O|rcsb pdb:6Z2W|rcsb pdb:6Z2X|rcsb pdb:6Z3A	-	crc64:E981C1A38F3310BF	crc64:C06AEF9F0484A615	figure legend:SUpp. Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/06/26	2018/07/10	rogid:qx0fM2HHwEI/GtbjRXu8kQrSp5w559292	rogid:BXSOV2x+FVvpAqOdHUGcYrTCN0A559292	rigid:QTC8BxVajulQ/dpgaph2wZf+dIY	false	-	flag tag:c-c	2	2	psi-mi:"MI:0815"(confirmation by molecular weight)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0815"(confirmation by molecular weight)|psi-mi:"MI:2287"(identification by structure determination)