#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-20738417|imex:IM-26520-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:f1f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/09/03	2018/09/11	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	glutathione s tranferase tag:?-?|binding-associated region:1225-1325	his tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20738440|imex:IM-26520-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-m07e)|taxid:9606(Homo sapiens hematopoietic cells)	-	2018/09/03	2018/09/11	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20738444|imex:IM-26520-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-m07e)|taxid:9606(Homo sapiens hematopoietic cells)	-	2018/09/03	2018/09/11	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20738471|imex:IM-26520-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:f2c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/09/03	2018/09/11	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	green fluorescent protein tag:n-n|necessary binding region:1322-1325	his tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20738711|imex:IM-26520-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:f2f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/09/03	2018/09/12	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	-	glycosylphosphatidylinositolated residue:?-?|necessary binding region:83-160	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0471"(MINT)	intact:EBI-20738726|imex:IM-26520-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:f2g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-m07e)|taxid:9606(Homo sapiens hematopoietic cells)	-	2018/09/03	2018/09/12	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	-	-	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-20738739|imex:IM-26520-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:sf1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:607.0x10^-9(molar)	2018/09/03	2018/09/12	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	binding-associated region:1319-1325|fluorescein label:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0471"(MINT)	intact:EBI-20739994|imex:IM-26520-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/09/03	2018/09/13	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	necessary binding region:1322-1325	-	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:1016"(fluorescence recovery after photobleaching)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20740008|imex:IM-26520-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:sf3b sf3c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/09/03	2018/09/13	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	green fluorescent protein tag:n-n|necessary binding region:1322-1325	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O15439	uniprotkb:Q00013	intact:EBI-4319622|uniprotkb:A9Z1Z7|uniprotkb:Q8IZN6|uniprotkb:Q8NEW8|uniprotkb:Q9Y6J2|uniprotkb:B7Z3Q7|uniprotkb:Q8IVZ4|ensembl:ENSP00000494609	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:mrp4_human(display_long)|uniprotkb:ABCC4(gene name)|psi-mi:ABCC4(display_short)|uniprotkb:MRP4(gene name synonym)|uniprotkb:MRP/cMOAT-related ABC transporter(gene name synonym)|uniprotkb:Multi-specific organic anion transporter B(gene name synonym)|uniprotkb:MOATB(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 4(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Pitre et al. (2017)	imex:IM-26520|pubmed:29146910	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-20740024|imex:IM-26520-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001098985.1|refseq:NP_005836.2|refseq:NP_001288758.1|refseq:NP_001288759.1|ensembl:ENSG00000125257(gene)|ensembl:ENST00000645237(transcript)|go:"GO:0001409"(guanine nucleotide transmembrane transporter activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015132"(prostaglandin transmembrane transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015432"(ABC-type bile acid transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015662"(P-type ion transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015732"(prostaglandin transport)|go:"GO:0015747"(urate transport)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0070730"(cAMP transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016404"("15-hydroxyprostaglandin dehydrogenase (NAD+) activity")|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0032310"(prostaglandin secretion)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030240|go:"GO:0034634"(glutathione transmembrane transporter activity)|interpro:IPR036640|mint:O15439|reactome:R-HSA-114608|reactome:R-HSA-382556	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	-	-	-	figure legend:f5a f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:511.0x10^-9(mol)	2018/09/03	2018/09/13	rogid:nFpsw6VYoGppeEna6rQFhMRxSVM9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:zbNXarFgkgP91GNFkUSznI/KdIg	false	necessary binding region:1301-1325|biotin tag:c-c	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)