#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9ULU4 uniprotkb:Q16643 intact:EBI-765834|uniprotkb:Q13517|uniprotkb:Q4JJ94|uniprotkb:Q4JJ95|uniprotkb:Q5TH09|uniprotkb:Q6MZM1|uniprotkb:Q8WXC5|uniprotkb:Q9H1F3|uniprotkb:Q9H1F4|uniprotkb:Q9H1F5|uniprotkb:Q9H1L8|uniprotkb:Q9H1L9|uniprotkb:Q9H2G5|uniprotkb:Q9NYN3|uniprotkb:Q9UIX6|uniprotkb:Q2HXV7|uniprotkb:E1P5U5|uniprotkb:B7Z680|uniprotkb:Q2HXV2|uniprotkb:Q2HXV8|uniprotkb:Q2HXW0|uniprotkb:Q2HXW1|uniprotkb:Q2HXW2|uniprotkb:Q2HXV4|uniprotkb:Q2HXV9|uniprotkb:B3KVL2|uniprotkb:B7Z2A8|uniprotkb:B7Z3E0|uniprotkb:B7ZM62|uniprotkb:F5H0X3|uniprotkb:H7C0U2|uniprotkb:J3KPU3|uniprotkb:Q2HXV1|uniprotkb:Q2HXV3|uniprotkb:Q5TH11|ensembl:ENSP00000312237 intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|ensembl:ENSP00000308532|intact:EBI-4404710|uniprotkb:A8MV58 psi-mi:pkcb1_human(display_long)|uniprotkb:Rack7(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se14-3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 8(gene name synonym)|uniprotkb:ZMYND8(gene name)|psi-mi:ZMYND8(display_short)|uniprotkb:KIAA1125(gene name synonym)|uniprotkb:RACK7(gene name synonym)|uniprotkb:PRKCBP1(gene name synonym) psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yao et al. (2017) pubmed:28966017|imex:IM-26534 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-20764187|imex:IM-26534-1|wwpdb:5y1z - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036540.3|refseq:NP_898868.1|refseq:NP_898869.1|refseq:XP_011527053.1|refseq:NP_001268711.1|refseq:NP_001268706.1|refseq:NP_001268710.1|ensembl:ENST00000262975|ensembl:ENSP00000262975|ensembl:ENSP00000312237|ensembl:ENST00000352431|ensembl:ENSP00000335537|ensembl:ENST00000355972|ensembl:ENSP00000348246|ensembl:ENST00000360911|ensembl:ENSP00000354166|ensembl:ENST00000372023|ensembl:ENSP00000361093|ensembl:ENST00000396281|ensembl:ENSP00000379577|refseq:NP_001268702.1|refseq:NP_001268703.1|refseq:NP_001268704.1|refseq:NP_001268705.1|refseq:NP_001268707.1|refseq:NP_001268712.1|refseq:XP_005260417.1|refseq:XP_005260423.1|ensembl:ENST00000446994|ensembl:ENSP00000396725|ensembl:ENST00000458360|ensembl:ENSP00000392964|ensembl:ENST00000461685|ensembl:ENSP00000418210|ensembl:ENST00000471951|ensembl:ENSP00000420095|ensembl:ENST00000536340|ensembl:ENSP00000439800|ensembl:ENST00000540497|ensembl:ENSP00000443086|refseq:NP_001268713.1|refseq:XP_005260413.1|refseq:NP_001268700.1|refseq:NP_001268701.1|refseq:XP_006723825.1|refseq:XP_016883250.1|refseq:XP_016883256.1|refseq:XP_016883257.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR021931|interpro:IPR035505|interpro:IPR036427|interpro:IPR037967|interpro:IPR044075|mint:Q9ULU4|rcsb pdb:4COS|rcsb pdb:5B73|rcsb pdb:5MQ4|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5Y1Z|ensembl:ENSG00000101040(gene)|ensembl:ENST00000311275(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus) refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758(gene)|ensembl:ENST00000309007(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0042641"(actomyosin)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q16643|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|go:"GO:0032507"(maintenance of protein location in cell)|refseq:XP_016864629.1 - - - figure legend:Table 1|3d-resolution:2.68A|3d-r-factors:R working 0.178 R free 0.234|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/09/18 2018/09/19 rogid:z46jFcDnmKauE75GMeApPZmfdDM9606 rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606 rigid:DqyvdyTMfF0Yox2u4diHlor7GEA false sufficient binding region:83-406 sufficient binding region:1-135(IPR002108) 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULU4 uniprotkb:Q16643 intact:EBI-765834|uniprotkb:Q13517|uniprotkb:Q4JJ94|uniprotkb:Q4JJ95|uniprotkb:Q5TH09|uniprotkb:Q6MZM1|uniprotkb:Q8WXC5|uniprotkb:Q9H1F3|uniprotkb:Q9H1F4|uniprotkb:Q9H1F5|uniprotkb:Q9H1L8|uniprotkb:Q9H1L9|uniprotkb:Q9H2G5|uniprotkb:Q9NYN3|uniprotkb:Q9UIX6|uniprotkb:Q2HXV7|uniprotkb:E1P5U5|uniprotkb:B7Z680|uniprotkb:Q2HXV2|uniprotkb:Q2HXV8|uniprotkb:Q2HXW0|uniprotkb:Q2HXW1|uniprotkb:Q2HXW2|uniprotkb:Q2HXV4|uniprotkb:Q2HXV9|uniprotkb:B3KVL2|uniprotkb:B7Z2A8|uniprotkb:B7Z3E0|uniprotkb:B7ZM62|uniprotkb:F5H0X3|uniprotkb:H7C0U2|uniprotkb:J3KPU3|uniprotkb:Q2HXV1|uniprotkb:Q2HXV3|uniprotkb:Q5TH11|ensembl:ENSP00000312237 intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|ensembl:ENSP00000308532|intact:EBI-4404710|uniprotkb:A8MV58 psi-mi:pkcb1_human(display_long)|uniprotkb:Rack7(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se14-3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 8(gene name synonym)|uniprotkb:ZMYND8(gene name)|psi-mi:ZMYND8(display_short)|uniprotkb:KIAA1125(gene name synonym)|uniprotkb:RACK7(gene name synonym)|uniprotkb:PRKCBP1(gene name synonym) psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Yao et al. (2017) pubmed:28966017|imex:IM-26534 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-20764237|imex:IM-26534-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036540.3|refseq:NP_898868.1|refseq:NP_898869.1|refseq:XP_011527053.1|refseq:NP_001268711.1|refseq:NP_001268706.1|refseq:NP_001268710.1|ensembl:ENST00000262975|ensembl:ENSP00000262975|ensembl:ENSP00000312237|ensembl:ENST00000352431|ensembl:ENSP00000335537|ensembl:ENST00000355972|ensembl:ENSP00000348246|ensembl:ENST00000360911|ensembl:ENSP00000354166|ensembl:ENST00000372023|ensembl:ENSP00000361093|ensembl:ENST00000396281|ensembl:ENSP00000379577|refseq:NP_001268702.1|refseq:NP_001268703.1|refseq:NP_001268704.1|refseq:NP_001268705.1|refseq:NP_001268707.1|refseq:NP_001268712.1|refseq:XP_005260417.1|refseq:XP_005260423.1|ensembl:ENST00000446994|ensembl:ENSP00000396725|ensembl:ENST00000458360|ensembl:ENSP00000392964|ensembl:ENST00000461685|ensembl:ENSP00000418210|ensembl:ENST00000471951|ensembl:ENSP00000420095|ensembl:ENST00000536340|ensembl:ENSP00000439800|ensembl:ENST00000540497|ensembl:ENSP00000443086|refseq:NP_001268713.1|refseq:XP_005260413.1|refseq:NP_001268700.1|refseq:NP_001268701.1|refseq:XP_006723825.1|refseq:XP_016883250.1|refseq:XP_016883256.1|refseq:XP_016883257.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR021931|interpro:IPR035505|interpro:IPR036427|interpro:IPR037967|interpro:IPR044075|mint:Q9ULU4|rcsb pdb:4COS|rcsb pdb:5B73|rcsb pdb:5MQ4|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5Y1Z|ensembl:ENSG00000101040(gene)|ensembl:ENST00000311275(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus) refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758(gene)|ensembl:ENST00000309007(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0042641"(actomyosin)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q16643|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|go:"GO:0032507"(maintenance of protein location in cell)|refseq:XP_016864629.1 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/09/18 2018/09/19 rogid:z46jFcDnmKauE75GMeApPZmfdDM9606 rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606 rigid:DqyvdyTMfF0Yox2u4diHlor7GEA false sufficient binding region:83-406 sufficient binding region:1-135(IPR002108) 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULU4 uniprotkb:Q16643 intact:EBI-765834|uniprotkb:Q13517|uniprotkb:Q4JJ94|uniprotkb:Q4JJ95|uniprotkb:Q5TH09|uniprotkb:Q6MZM1|uniprotkb:Q8WXC5|uniprotkb:Q9H1F3|uniprotkb:Q9H1F4|uniprotkb:Q9H1F5|uniprotkb:Q9H1L8|uniprotkb:Q9H1L9|uniprotkb:Q9H2G5|uniprotkb:Q9NYN3|uniprotkb:Q9UIX6|uniprotkb:Q2HXV7|uniprotkb:E1P5U5|uniprotkb:B7Z680|uniprotkb:Q2HXV2|uniprotkb:Q2HXV8|uniprotkb:Q2HXW0|uniprotkb:Q2HXW1|uniprotkb:Q2HXW2|uniprotkb:Q2HXV4|uniprotkb:Q2HXV9|uniprotkb:B3KVL2|uniprotkb:B7Z2A8|uniprotkb:B7Z3E0|uniprotkb:B7ZM62|uniprotkb:F5H0X3|uniprotkb:H7C0U2|uniprotkb:J3KPU3|uniprotkb:Q2HXV1|uniprotkb:Q2HXV3|uniprotkb:Q5TH11|ensembl:ENSP00000312237 intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|ensembl:ENSP00000308532|intact:EBI-4404710|uniprotkb:A8MV58 psi-mi:pkcb1_human(display_long)|uniprotkb:Rack7(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se14-3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 8(gene name synonym)|uniprotkb:ZMYND8(gene name)|psi-mi:ZMYND8(display_short)|uniprotkb:KIAA1125(gene name synonym)|uniprotkb:RACK7(gene name synonym)|uniprotkb:PRKCBP1(gene name synonym) psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Yao et al. (2017) pubmed:28966017|imex:IM-26534 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-20764255|imex:IM-26534-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036540.3|refseq:NP_898868.1|refseq:NP_898869.1|refseq:XP_011527053.1|refseq:NP_001268711.1|refseq:NP_001268706.1|refseq:NP_001268710.1|ensembl:ENST00000262975|ensembl:ENSP00000262975|ensembl:ENSP00000312237|ensembl:ENST00000352431|ensembl:ENSP00000335537|ensembl:ENST00000355972|ensembl:ENSP00000348246|ensembl:ENST00000360911|ensembl:ENSP00000354166|ensembl:ENST00000372023|ensembl:ENSP00000361093|ensembl:ENST00000396281|ensembl:ENSP00000379577|refseq:NP_001268702.1|refseq:NP_001268703.1|refseq:NP_001268704.1|refseq:NP_001268705.1|refseq:NP_001268707.1|refseq:NP_001268712.1|refseq:XP_005260417.1|refseq:XP_005260423.1|ensembl:ENST00000446994|ensembl:ENSP00000396725|ensembl:ENST00000458360|ensembl:ENSP00000392964|ensembl:ENST00000461685|ensembl:ENSP00000418210|ensembl:ENST00000471951|ensembl:ENSP00000420095|ensembl:ENST00000536340|ensembl:ENSP00000439800|ensembl:ENST00000540497|ensembl:ENSP00000443086|refseq:NP_001268713.1|refseq:XP_005260413.1|refseq:NP_001268700.1|refseq:NP_001268701.1|refseq:XP_006723825.1|refseq:XP_016883250.1|refseq:XP_016883256.1|refseq:XP_016883257.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR021931|interpro:IPR035505|interpro:IPR036427|interpro:IPR037967|interpro:IPR044075|mint:Q9ULU4|rcsb pdb:4COS|rcsb pdb:5B73|rcsb pdb:5MQ4|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5Y1Z|ensembl:ENSG00000101040(gene)|ensembl:ENST00000311275(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus) refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758(gene)|ensembl:ENST00000309007(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0042641"(actomyosin)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q16643|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|go:"GO:0032507"(maintenance of protein location in cell)|refseq:XP_016864629.1 - - - figure legend:Fig. 1C, 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:4.3x10^-6(molar) 2018/09/18 2018/09/19 rogid:z46jFcDnmKauE75GMeApPZmfdDM9606 rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606 rigid:DqyvdyTMfF0Yox2u4diHlor7GEA false sufficient binding region:83-406 sufficient binding region:1-135(IPR002108) 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULU4 uniprotkb:Q16643 intact:EBI-765834|uniprotkb:Q13517|uniprotkb:Q4JJ94|uniprotkb:Q4JJ95|uniprotkb:Q5TH09|uniprotkb:Q6MZM1|uniprotkb:Q8WXC5|uniprotkb:Q9H1F3|uniprotkb:Q9H1F4|uniprotkb:Q9H1F5|uniprotkb:Q9H1L8|uniprotkb:Q9H1L9|uniprotkb:Q9H2G5|uniprotkb:Q9NYN3|uniprotkb:Q9UIX6|uniprotkb:Q2HXV7|uniprotkb:E1P5U5|uniprotkb:B7Z680|uniprotkb:Q2HXV2|uniprotkb:Q2HXV8|uniprotkb:Q2HXW0|uniprotkb:Q2HXW1|uniprotkb:Q2HXW2|uniprotkb:Q2HXV4|uniprotkb:Q2HXV9|uniprotkb:B3KVL2|uniprotkb:B7Z2A8|uniprotkb:B7Z3E0|uniprotkb:B7ZM62|uniprotkb:F5H0X3|uniprotkb:H7C0U2|uniprotkb:J3KPU3|uniprotkb:Q2HXV1|uniprotkb:Q2HXV3|uniprotkb:Q5TH11|ensembl:ENSP00000312237 intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|ensembl:ENSP00000308532|intact:EBI-4404710|uniprotkb:A8MV58 psi-mi:pkcb1_human(display_long)|uniprotkb:Rack7(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se14-3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 8(gene name synonym)|uniprotkb:ZMYND8(gene name)|psi-mi:ZMYND8(display_short)|uniprotkb:KIAA1125(gene name synonym)|uniprotkb:RACK7(gene name synonym)|uniprotkb:PRKCBP1(gene name synonym) psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Yao et al. (2017) pubmed:28966017|imex:IM-26534 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-20764272|imex:IM-26534-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036540.3|refseq:NP_898868.1|refseq:NP_898869.1|refseq:XP_011527053.1|refseq:NP_001268711.1|refseq:NP_001268706.1|refseq:NP_001268710.1|ensembl:ENST00000262975|ensembl:ENSP00000262975|ensembl:ENSP00000312237|ensembl:ENST00000352431|ensembl:ENSP00000335537|ensembl:ENST00000355972|ensembl:ENSP00000348246|ensembl:ENST00000360911|ensembl:ENSP00000354166|ensembl:ENST00000372023|ensembl:ENSP00000361093|ensembl:ENST00000396281|ensembl:ENSP00000379577|refseq:NP_001268702.1|refseq:NP_001268703.1|refseq:NP_001268704.1|refseq:NP_001268705.1|refseq:NP_001268707.1|refseq:NP_001268712.1|refseq:XP_005260417.1|refseq:XP_005260423.1|ensembl:ENST00000446994|ensembl:ENSP00000396725|ensembl:ENST00000458360|ensembl:ENSP00000392964|ensembl:ENST00000461685|ensembl:ENSP00000418210|ensembl:ENST00000471951|ensembl:ENSP00000420095|ensembl:ENST00000536340|ensembl:ENSP00000439800|ensembl:ENST00000540497|ensembl:ENSP00000443086|refseq:NP_001268713.1|refseq:XP_005260413.1|refseq:NP_001268700.1|refseq:NP_001268701.1|refseq:XP_006723825.1|refseq:XP_016883250.1|refseq:XP_016883256.1|refseq:XP_016883257.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR021931|interpro:IPR035505|interpro:IPR036427|interpro:IPR037967|interpro:IPR044075|mint:Q9ULU4|rcsb pdb:4COS|rcsb pdb:5B73|rcsb pdb:5MQ4|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5Y1Z|ensembl:ENSG00000101040(gene)|ensembl:ENST00000311275(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus) refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758(gene)|ensembl:ENST00000309007(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0042641"(actomyosin)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q16643|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|go:"GO:0032507"(maintenance of protein location in cell)|refseq:XP_016864629.1 go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 5A, 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2018/09/18 2018/09/19 rogid:z46jFcDnmKauE75GMeApPZmfdDM9606 rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606 rigid:DqyvdyTMfF0Yox2u4diHlor7GEA false myc tag:?-?|mutation disrupting interaction strength:311-311 ha tag:?-?(IPR002108)|mutation disrupting interaction strength:10-10 - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)