#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NZV6	uniprotkb:P05067-PRO_0000000092	intact:EBI-12330065|ensembl:ENSP00000355084|uniprotkb:Q96RX6|uniprotkb:Q9BTV2|uniprotkb:Q9P0B1	intact:EBI-821758	psi-mi:msrb1_human(display_long)|uniprotkb:MSRB1(gene name)|psi-mi:MSRB1(display_short)|uniprotkb:SEPX1(gene name synonym)|uniprotkb:Selenoprotein X(gene name synonym)|uniprotkb:HSPC270(orf name)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:1016"(fluorescence recovery after photobleaching)	Wang et al. (2017)	imex:IM-26882|pubmed:28579431	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20976309|imex:IM-26882-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198736(gene)|ensembl:ENST00000361871(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0033745"("L-methionine-(R)-S-oxide reductase activity")|go:"GO:0045087"(innate immune response)|go:"GO:0070191"(methionine-R-sulfoxide reductase activity)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|rcsb pdb:3MAO|reactome:R-HSA-5676934|refseq:NP_057416.1	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:Fig 1|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/11/23	2018/11/23	rogid:DR4z/+yUfitTjUy4b722w3qyTk89606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:jyT7UPv7K9OvGDbalyyCo3eQQEY	false	yellow fluorescent protein tag:?-?	cyan fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9NZV6	uniprotkb:P05067-PRO_0000000092	intact:EBI-12330065|ensembl:ENSP00000355084|uniprotkb:Q96RX6|uniprotkb:Q9BTV2|uniprotkb:Q9P0B1	intact:EBI-821758	psi-mi:msrb1_human(display_long)|uniprotkb:MSRB1(gene name)|psi-mi:MSRB1(display_short)|uniprotkb:SEPX1(gene name synonym)|uniprotkb:Selenoprotein X(gene name synonym)|uniprotkb:HSPC270(orf name)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2017)	imex:IM-26882|pubmed:28579431	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20976345|imex:IM-26882-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198736(gene)|ensembl:ENST00000361871(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0033745"("L-methionine-(R)-S-oxide reductase activity")|go:"GO:0045087"(innate immune response)|go:"GO:0070191"(methionine-R-sulfoxide reductase activity)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|rcsb pdb:3MAO|reactome:R-HSA-5676934|refseq:NP_057416.1	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:Fig 2|comment:Interaction confirmed by anti-bait western|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/11/23	2018/11/23	rogid:DR4z/+yUfitTjUy4b722w3qyTk89606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:jyT7UPv7K9OvGDbalyyCo3eQQEY	false	myc tag:?-?	cyan fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NZV6	uniprotkb:P05067-PRO_0000000092	intact:EBI-12330065|ensembl:ENSP00000355084|uniprotkb:Q96RX6|uniprotkb:Q9BTV2|uniprotkb:Q9P0B1	intact:EBI-821758	psi-mi:msrb1_human(display_long)|uniprotkb:MSRB1(gene name)|psi-mi:MSRB1(display_short)|uniprotkb:SEPX1(gene name synonym)|uniprotkb:Selenoprotein X(gene name synonym)|uniprotkb:HSPC270(orf name)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2017)	imex:IM-26882|pubmed:28579431	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20976356|imex:IM-26882-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198736(gene)|ensembl:ENST00000361871(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0033745"("L-methionine-(R)-S-oxide reductase activity")|go:"GO:0045087"(innate immune response)|go:"GO:0070191"(methionine-R-sulfoxide reductase activity)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|rcsb pdb:3MAO|reactome:R-HSA-5676934|refseq:NP_057416.1	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:Fig 2|comment:Interaction confirmed by anti-bait western|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/11/23	2018/11/23	rogid:DR4z/+yUfitTjUy4b722w3qyTk89606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:jyT7UPv7K9OvGDbalyyCo3eQQEY	false	myc tag:?-?	cyan fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NZV6	uniprotkb:P05067-PRO_0000000092	intact:EBI-12330065|ensembl:ENSP00000355084|uniprotkb:Q96RX6|uniprotkb:Q9BTV2|uniprotkb:Q9P0B1	intact:EBI-821758	psi-mi:msrb1_human(display_long)|uniprotkb:MSRB1(gene name)|psi-mi:MSRB1(display_short)|uniprotkb:SEPX1(gene name synonym)|uniprotkb:Selenoprotein X(gene name synonym)|uniprotkb:HSPC270(orf name)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2017)	imex:IM-26882|pubmed:28579431	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20976373|imex:IM-26882-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198736(gene)|ensembl:ENST00000361871(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0033745"("L-methionine-(R)-S-oxide reductase activity")|go:"GO:0045087"(innate immune response)|go:"GO:0070191"(methionine-R-sulfoxide reductase activity)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|rcsb pdb:3MAO|reactome:R-HSA-5676934|refseq:NP_057416.1	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:Fig 3|comment:Interaction confirmed by anti-bait western|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/11/23	2019/02/27	rogid:DR4z/+yUfitTjUy4b722w3qyTk89606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:jyT7UPv7K9OvGDbalyyCo3eQQEY	false	myc tag:?-?	cyan fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)