#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9ERD7	uniprotkb:O08747	intact:EBI-2255594|uniprotkb:Q3UF42|uniprotkb:Q5I036|ensembl:ENSMUSP00000071134	intact:EBI-21004500|ensembl:ENSMUSP00000101843|uniprotkb:Q8CD16	psi-mi:tbb3_mouse(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short)	psi-mi:unc5c_mouse(display_long)|uniprotkb:Protein unc-5 homolog 3(gene name synonym)|uniprotkb:Protein unc-5 homolog C(gene name synonym)|uniprotkb:Rostral cerebellar malformation protein(gene name synonym)|uniprotkb:Unc5c(gene name)|psi-mi:Unc5c(display_short)|uniprotkb:Rcm(gene name synonym)|uniprotkb:Unc5h3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Shao et al. (2017)	pubmed:28483977|imex:IM-26990	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21004440|imex:IM-26990-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075768.1|dip:DIP-48419N|ensembl:ENSMUSG00000062380(gene)|ensembl:ENSMUST00000071134(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9ERD7|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	ensembl:ENSMUSG00000059921(gene)|ensembl:ENSMUST00000106236(transcript)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005043"(netrin receptor activity involved in chemorepulsion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0009986"(cell surface)|go:"GO:0015631"(tubulin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:1990791"(dorsal root ganglion development)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036383|interpro:IPR037936|interpro:IPR042154|interpro:IPR036179|refseq:NP_033498.1	-	-	-	figure legend:Fig. 1B|antagonist:Netrin-1|sample process:"To determine whether endogenous TUBB3 interacted with UNC5C, we performed coimmunoprecipitation on the lysates of dissociated cerebellar neurons from postnatal day 4 (P4) mice"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2018/12/10	2018/12/10	rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810090	rogid:yFFjhOzp5A0VRUw8rdQnJxVT6Co10090	rigid:itqpOLrxO4Yh6ewVUZgW8JbOUb8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9ERD7	uniprotkb:O08747	intact:EBI-2255594|uniprotkb:Q3UF42|uniprotkb:Q5I036|ensembl:ENSMUSP00000071134	intact:EBI-21004500|ensembl:ENSMUSP00000101843|uniprotkb:Q8CD16	psi-mi:tbb3_mouse(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short)	psi-mi:unc5c_mouse(display_long)|uniprotkb:Protein unc-5 homolog 3(gene name synonym)|uniprotkb:Protein unc-5 homolog C(gene name synonym)|uniprotkb:Rostral cerebellar malformation protein(gene name synonym)|uniprotkb:Unc5c(gene name)|psi-mi:Unc5c(display_short)|uniprotkb:Rcm(gene name synonym)|uniprotkb:Unc5h3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Shao et al. (2017)	pubmed:28483977|imex:IM-26990	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21004542|imex:IM-26990-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075768.1|dip:DIP-48419N|ensembl:ENSMUSG00000062380(gene)|ensembl:ENSMUST00000071134(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9ERD7|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	ensembl:ENSMUSG00000059921(gene)|ensembl:ENSMUST00000106236(transcript)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005043"(netrin receptor activity involved in chemorepulsion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0009986"(cell surface)|go:"GO:0015631"(tubulin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:1990791"(dorsal root ganglion development)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036383|interpro:IPR037936|interpro:IPR042154|interpro:IPR036179|refseq:NP_033498.1	-	-	-	figure legend:Fig. 1B, 1D-F, 3A|antagonist:Netrin-1|comment:Pretreatment with Taxol or nocodazole abolished the ability of netrin-1 to reduce the TUBB3/UNC5C interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2018/12/10	2018/12/10	rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810090	rogid:yFFjhOzp5A0VRUw8rdQnJxVT6Co10090	rigid:itqpOLrxO4Yh6ewVUZgW8JbOUb8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13509	uniprotkb:O95185	intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854	intact:EBI-11343380|uniprotkb:Q8IUT0|ensembl:ENSP00000406022	psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:unc5c_human(display_long)|uniprotkb:UNC5C(gene name)|psi-mi:UNC5C(display_short)|uniprotkb:Protein unc-5 homolog 3(gene name synonym)|uniprotkb:Protein unc-5 homolog C(gene name synonym)|uniprotkb:UNC5H3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shao et al. (2017)	pubmed:28483977|imex:IM-26990	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21004554|imex:IM-26990-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N	refseq:NP_003719.3|dip:DIP-46276N|ensembl:ENSG00000182168(gene)|ensembl:ENST00000453304(transcript)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005043"(netrin receptor activity involved in chemorepulsion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0009986"(cell surface)|go:"GO:0015631"(tubulin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:1990791"(dorsal root ganglion development)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042154|reactome:R-HSA-418886	-	-	-	figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2018/12/10	2018/12/10	rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606	rogid:017DIujoFNwrZZnVrEGkOsUSVLU9606	rigid:yYd3EFQoe6hk1VvAnrUHqvOekeg	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13509	uniprotkb:O95185	intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854	intact:EBI-11343380|uniprotkb:Q8IUT0|ensembl:ENSP00000406022	psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:unc5c_human(display_long)|uniprotkb:UNC5C(gene name)|psi-mi:UNC5C(display_short)|uniprotkb:Protein unc-5 homolog 3(gene name synonym)|uniprotkb:Protein unc-5 homolog C(gene name synonym)|uniprotkb:UNC5H3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shao et al. (2017)	pubmed:28483977|imex:IM-26990	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21004569|imex:IM-26990-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N	refseq:NP_003719.3|dip:DIP-46276N|ensembl:ENSG00000182168(gene)|ensembl:ENST00000453304(transcript)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005043"(netrin receptor activity involved in chemorepulsion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0009986"(cell surface)|go:"GO:0015631"(tubulin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:1990791"(dorsal root ganglion development)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042154|reactome:R-HSA-418886	-	-	-	figure legend:Fig. 1G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/12/10	2018/12/10	rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606	rogid:017DIujoFNwrZZnVrEGkOsUSVLU9606	rigid:yYd3EFQoe6hk1VvAnrUHqvOekeg	false	his tag:n-n	glutathione s tranferase tag:?-?|sufficient binding region:381..381-931	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9ERD7	uniprotkb:O08747	intact:EBI-2255594|uniprotkb:Q3UF42|uniprotkb:Q5I036|ensembl:ENSMUSP00000071134	intact:EBI-21004500|ensembl:ENSMUSP00000101843|uniprotkb:Q8CD16	psi-mi:tbb3_mouse(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short)	psi-mi:unc5c_mouse(display_long)|uniprotkb:Protein unc-5 homolog 3(gene name synonym)|uniprotkb:Protein unc-5 homolog C(gene name synonym)|uniprotkb:Rostral cerebellar malformation protein(gene name synonym)|uniprotkb:Unc5c(gene name)|psi-mi:Unc5c(display_short)|uniprotkb:Rcm(gene name synonym)|uniprotkb:Unc5h3(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Shao et al. (2017)	pubmed:28483977|imex:IM-26990	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21004588|imex:IM-26990-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075768.1|dip:DIP-48419N|ensembl:ENSMUSG00000062380(gene)|ensembl:ENSMUST00000071134(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9ERD7|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	ensembl:ENSMUSG00000059921(gene)|ensembl:ENSMUST00000106236(transcript)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005043"(netrin receptor activity involved in chemorepulsion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0009986"(cell surface)|go:"GO:0015631"(tubulin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:1990791"(dorsal root ganglion development)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036383|interpro:IPR037936|interpro:IPR042154|interpro:IPR036179|refseq:NP_033498.1	go:"GO:0030426"(growth cone)	-	-	figure legend:Fig. 2|antagonist:Netrin-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2018/12/10	2018/12/10	rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810090	rogid:yFFjhOzp5A0VRUw8rdQnJxVT6Co10090	rigid:itqpOLrxO4Yh6ewVUZgW8JbOUb8	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)