#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:16761"	chebi:"CHEBI:133748"	intact:EBI-1188073	intact:EBI-16824799	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:citrate anion(display_short)|psi-mi:"CHEBI:133748"(display_long)|intact:citrate(synonym)|intact:citrate anions(synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824784|wwpdb:5gre|imex:IM-26354-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:Table 1|3d-resolution:2.65A|3d-r-factors:Rworking 0.195 Rfree 0.241|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	-	-	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	uniprotkb:P50213	intact:EBI-1188073	intact:EBI-355999|uniprotkb:D3DW83|uniprotkb:Q9H3X0|ensembl:ENSP00000299518	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:idh3a_human(display_long)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824784|wwpdb:5gre|imex:IM-26354-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005521.1|interpro:IPR024084|ensembl:ENSG00000166411(gene)|ensembl:ENST00000299518(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|mint:P50213|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-71403	-	-	-	figure legend:Table 1|3d-resolution:2.65A|3d-r-factors:Rworking 0.195 Rfree 0.241|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	rogid:JvAUAMJ0DcgnIfvy/vlfRyXYzhE9606	-	false	-	sufficient binding region:28-366	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	uniprotkb:P51553	intact:EBI-1188073	intact:EBI-1210876|uniprotkb:Q9BUU5|uniprotkb:E9PDD5|ensembl:ENSP00000217901	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:idh3g_human(display_long)|uniprotkb:IDH3G(gene name)|psi-mi:IDH3G(display_short)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824784|wwpdb:5gre|imex:IM-26354-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004126.1|refseq:NP_777358.1|ensembl:ENSG00000067829(gene)|ensembl:ENST00000217901(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P51553|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-1268020|reactome:R-HSA-71403	-	-	-	figure legend:Table 1|3d-resolution:2.65A|3d-r-factors:Rworking 0.195 Rfree 0.241|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	rogid:CQ3xfzDzQreBvU2mRPSg5xUfjKY9606	-	false	-	sufficient binding region:40-393	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	chebi:"CHEBI:18420"	intact:EBI-1188073	intact:EBI-967760	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:"magnesium(2+)"(display_short)|psi-mi:"CHEBI:18420"(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824784|wwpdb:5gre|imex:IM-26354-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:Table 1|3d-resolution:2.65A|3d-r-factors:Rworking 0.195 Rfree 0.241|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	-	-	false	-	-	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	uniprotkb:P50213	intact:EBI-1188073	intact:EBI-355999|uniprotkb:D3DW83|uniprotkb:Q9H3X0|ensembl:ENSP00000299518	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:idh3a_human(display_long)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824806|wwpdb:5grl|imex:IM-26354-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005521.1|interpro:IPR024084|ensembl:ENSG00000166411(gene)|ensembl:ENST00000299518(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|mint:P50213|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-71403	-	-	-	figure legend:Table 1|3d-resolution:2.79A|3d-r-factors:Rworking 0.226 Rfree 0.274|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	rogid:JvAUAMJ0DcgnIfvy/vlfRyXYzhE9606	-	false	-	sufficient binding region:28-366	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	uniprotkb:P51553	intact:EBI-1188073	intact:EBI-1210876|uniprotkb:Q9BUU5|uniprotkb:E9PDD5|ensembl:ENSP00000217901	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:idh3g_human(display_long)|uniprotkb:IDH3G(gene name)|psi-mi:IDH3G(display_short)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824806|wwpdb:5grl|imex:IM-26354-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004126.1|refseq:NP_777358.1|ensembl:ENSG00000067829(gene)|ensembl:ENST00000217901(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P51553|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-1268020|reactome:R-HSA-71403	-	-	-	figure legend:Table 1|3d-resolution:2.79A|3d-r-factors:Rworking 0.226 Rfree 0.274|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	rogid:CQ3xfzDzQreBvU2mRPSg5xUfjKY9606	-	false	-	sufficient binding region:40-393	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	chebi:"CHEBI:36453"	intact:EBI-1188073	intact:EBI-16824819	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:"isocitrate(2-)"(display_short)|psi-mi:"CHEBI:36453"(display_long)|intact:hydrogen isocitrate(synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824806|wwpdb:5grl|imex:IM-26354-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:Table 1|3d-resolution:2.79A|3d-r-factors:Rworking 0.226 Rfree 0.274|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	-	-	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	chebi:"CHEBI:18420"	intact:EBI-1188073	intact:EBI-967760	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:"magnesium(2+)"(display_short)|psi-mi:"CHEBI:18420"(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824806|wwpdb:5grl|imex:IM-26354-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:Table 1|3d-resolution:2.79A|3d-r-factors:Rworking 0.226 Rfree 0.274|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	-	-	false	-	-	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	chebi:"CHEBI:133748"	intact:EBI-1188073	intact:EBI-16824799	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:citrate anion(display_short)|psi-mi:"CHEBI:133748"(display_long)|intact:citrate(synonym)|intact:citrate anions(synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824830|wwpdb:5grf|imex:IM-26354-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:Table 1|3d-resolution:2.5A|3d-r-factors:Rworking 0.207 Rfree 0.248|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	-	-	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	uniprotkb:P50213	intact:EBI-1188073	intact:EBI-355999|uniprotkb:D3DW83|uniprotkb:Q9H3X0|ensembl:ENSP00000299518	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:idh3a_human(display_long)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824830|wwpdb:5grf|imex:IM-26354-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005521.1|interpro:IPR024084|ensembl:ENSG00000166411(gene)|ensembl:ENST00000299518(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|mint:P50213|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-71403	-	-	-	figure legend:Table 1|3d-resolution:2.5A|3d-r-factors:Rworking 0.207 Rfree 0.248|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	rogid:JvAUAMJ0DcgnIfvy/vlfRyXYzhE9606	-	false	-	sufficient binding region:28-366	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	uniprotkb:P51553	intact:EBI-1188073	intact:EBI-1210876|uniprotkb:Q9BUU5|uniprotkb:E9PDD5|ensembl:ENSP00000217901	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:idh3g_human(display_long)|uniprotkb:IDH3G(gene name)|psi-mi:IDH3G(display_short)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824830|wwpdb:5grf|imex:IM-26354-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004126.1|refseq:NP_777358.1|ensembl:ENSG00000067829(gene)|ensembl:ENST00000217901(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P51553|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-1268020|reactome:R-HSA-71403	-	-	-	figure legend:Table 1|3d-resolution:2.5A|3d-r-factors:Rworking 0.207 Rfree 0.248|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	rogid:CQ3xfzDzQreBvU2mRPSg5xUfjKY9606	-	false	-	sufficient binding region:40-393|mutation:190-190	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	chebi:"CHEBI:18420"	intact:EBI-1188073	intact:EBI-967760	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:"magnesium(2+)"(display_short)|psi-mi:"CHEBI:18420"(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824830|wwpdb:5grf|imex:IM-26354-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:Table 1|3d-resolution:2.5A|3d-r-factors:Rworking 0.207 Rfree 0.248|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	-	-	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:133748"	uniprotkb:P50213	intact:EBI-16824799	intact:EBI-355999|uniprotkb:D3DW83|uniprotkb:Q9H3X0|ensembl:ENSP00000299518	psi-mi:citrate anion(display_short)|psi-mi:"CHEBI:133748"(display_long)|intact:citrate(synonym)|intact:citrate anions(synonym)	psi-mi:idh3a_human(display_long)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824846|wwpdb:5gri|imex:IM-26354-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005521.1|interpro:IPR024084|ensembl:ENSG00000166411(gene)|ensembl:ENST00000299518(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|mint:P50213|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-71403	-	-	-	figure legend:Table 1|3d-resolution:2.31A|3d-r-factors:Rworking 0.241 Rfree 0.271|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	rogid:JvAUAMJ0DcgnIfvy/vlfRyXYzhE9606	-	false	-	sufficient binding region:28-366	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:133748"	uniprotkb:P51553	intact:EBI-16824799	intact:EBI-1210876|uniprotkb:Q9BUU5|uniprotkb:E9PDD5|ensembl:ENSP00000217901	psi-mi:citrate anion(display_short)|psi-mi:"CHEBI:133748"(display_long)|intact:citrate(synonym)|intact:citrate anions(synonym)	psi-mi:idh3g_human(display_long)|uniprotkb:IDH3G(gene name)|psi-mi:IDH3G(display_short)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824846|wwpdb:5gri|imex:IM-26354-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004126.1|refseq:NP_777358.1|ensembl:ENSG00000067829(gene)|ensembl:ENST00000217901(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P51553|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-1268020|reactome:R-HSA-71403	-	-	-	figure legend:Table 1|3d-resolution:2.31A|3d-r-factors:Rworking 0.241 Rfree 0.271|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	rogid:CQ3xfzDzQreBvU2mRPSg5xUfjKY9606	-	false	-	sufficient binding region:40-393	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:133748"	chebi:"CHEBI:18420"	intact:EBI-16824799	intact:EBI-967760	psi-mi:citrate anion(display_short)|psi-mi:"CHEBI:133748"(display_long)|intact:citrate(synonym)|intact:citrate anions(synonym)	psi-mi:"magnesium(2+)"(display_short)|psi-mi:"CHEBI:18420"(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824846|wwpdb:5gri|imex:IM-26354-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:Table 1|3d-resolution:2.31A|3d-r-factors:Rworking 0.241 Rfree 0.271|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2018/03/02	-	-	-	false	-	-	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51553	uniprotkb:P50213	intact:EBI-1210876|uniprotkb:Q9BUU5|uniprotkb:E9PDD5|ensembl:ENSP00000217901	intact:EBI-355999|uniprotkb:D3DW83|uniprotkb:Q9H3X0|ensembl:ENSP00000299518	psi-mi:idh3g_human(display_long)|uniprotkb:IDH3G(gene name)|psi-mi:IDH3G(display_short)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)	psi-mi:idh3a_human(display_long)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ma et al. (2017)	pubmed:28098230|imex:IM-26354	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16824859|wwpdb:5grh|imex:IM-26354-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004126.1|refseq:NP_777358.1|ensembl:ENSG00000067829(gene)|ensembl:ENST00000217901(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P51553|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-1268020|reactome:R-HSA-71403	refseq:NP_005521.1|interpro:IPR024084|ensembl:ENSG00000166411(gene)|ensembl:ENST00000299518(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|mint:P50213|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-71403	-	-	-	figure legend:Table 1|3d-resolution:2.8A|3d-r-factors:Rworking 0.224 Rfree 0.259|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/31	2020/06/30	rogid:CQ3xfzDzQreBvU2mRPSg5xUfjKY9606	rogid:JvAUAMJ0DcgnIfvy/vlfRyXYzhE9606	rigid:1DiDoBm10edJILP2wIvY6JgGB6Q	false	sufficient binding region:40-393	sufficient binding region:28-366	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)