#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75311 uniprotkb:O75311 intact:EBI-16357053|ensembl:ENSP00000274093|uniprotkb:D3DP44|uniprotkb:O75816|uniprotkb:Q5D0E3 intact:EBI-16357053|ensembl:ENSP00000274093|uniprotkb:D3DP44|uniprotkb:O75816|uniprotkb:Q5D0E3 psi-mi:glra3_human(display_long)|uniprotkb:GLRA3(gene name)|psi-mi:GLRA3(display_short) psi-mi:glra3_human(display_long)|uniprotkb:GLRA3(gene name)|psi-mi:GLRA3(display_short) psi-mi:"MI:0114"(x-ray crystallography) Huang et al. (2017) pubmed:27991902|imex:IM-27796 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21012624|wwpdb:5TIN|imex:IM-27796-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145451(gene)|ensembl:ENST00000274093(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016594"(glycine binding)|go:"GO:0016934"(extracellularly glycine-gated chloride channel activity)|go:"GO:0016935"(glycine-gated chloride channel complex)|go:"GO:0022852"(glycine-gated chloride ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043200"(response to amino acid)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060012"(synaptic transmission, glycinergic)|go:"GO:1902476"(chloride transmembrane transport)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR008127(Glycine receptor alpha)|interpro:IPR008130(Glycine receptor alpha3)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|rcsb pdb:5CFB|rcsb pdb:5TIN|rcsb pdb:5TIO|rcsb pdb:5VDH|rcsb pdb:5VDI|reactome:R-HSA-112314|dip:DIP-61773N|refseq:NP_001036008.1|refseq:NP_006520.2 ensembl:ENSG00000145451(gene)|ensembl:ENST00000274093(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016594"(glycine binding)|go:"GO:0016934"(extracellularly glycine-gated chloride channel activity)|go:"GO:0016935"(glycine-gated chloride channel complex)|go:"GO:0022852"(glycine-gated chloride ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043200"(response to amino acid)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060012"(synaptic transmission, glycinergic)|go:"GO:1902476"(chloride transmembrane transport)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR008127(Glycine receptor alpha)|interpro:IPR008130(Glycine receptor alpha3)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|rcsb pdb:5CFB|rcsb pdb:5TIN|rcsb pdb:5TIO|rcsb pdb:5VDH|rcsb pdb:5VDI|reactome:R-HSA-112314|dip:DIP-61773N|refseq:NP_001036008.1|refseq:NP_006520.2 - - - figure legend:Table 1, Supplementary Fig 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2018/12/20 2020/03/13 rogid:T3U/p+n3CYq1VVy9QeEILtg6CN49606 rogid:T3U/p+n3CYq1VVy9QeEILtg6CN49606 rigid:7ryQ3Yn8CiwOz3197s5vv+na6qw false mutation:71-71 mutation:71-71 5 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)