#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P51513 uniprotkb:P18507 intact:EBI-726123|uniprotkb:Q6B004|uniprotkb:A8K0S4|uniprotkb:A8K4Q7|uniprotkb:D3DS82|uniprotkb:D3DS81|ensembl:ENSP00000438875 intact:EBI-9008430|uniprotkb:Q6GRL6|uniprotkb:Q6PCC3|uniprotkb:Q9UDB3|uniprotkb:F5HB82|uniprotkb:Q9UN15|ensembl:ENSP00000492125 psi-mi:nova1_human(display_long)|uniprotkb:Neuro-oncological ventral antigen 1(gene name synonym)|uniprotkb:Onconeural ventral antigen 1(gene name synonym)|uniprotkb:Paraneoplastic Ri antigen(gene name synonym)|uniprotkb:Ventral neuron-specific protein 1(gene name synonym)|uniprotkb:NOVA1(gene name)|psi-mi:NOVA1(display_short) psi-mi:gbrg2_human(display_long)|uniprotkb:GABRG2(gene name)|psi-mi:GABRG2(display_short)|uniprotkb:"GABA(A) receptor subunit gamma-2"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2016) pubmed:27733149|imex:IM-26644 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-20822269|imex:IM-26644-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002506.2|refseq:NP_006480.2|refseq:NP_006482.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|interpro:IPR036612|rcsb pdb:1DT4|rcsb pdb:2ANN|rcsb pdb:2ANR|interpro:IPR033086|ensembl:ENSG00000139910(gene)|ensembl:ENST00000539517(transcript) refseq:NP_000807.2|refseq:NP_944493.2|refseq:NP_944494.1|rcsb pdb:6HUP|rcsb pdb:6I53|rcsb pdb:6X3S|rcsb pdb:6X3T|rcsb pdb:6X3U|rcsb pdb:6X3V|rcsb pdb:6X3W|rcsb pdb:6X3X|rcsb pdb:6X3Z|rcsb pdb:6X40|reactome:R-HSA-1236394|reactome:R-HSA-977443|rcsb pdb:6HUO|ensembl:ENSG00000113327(gene)|ensembl:ENST00000639111(transcript)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008503"(benzodiazepine receptor activity)|go:"GO:0009791"(post-embryonic development)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030424"(axon)|go:"GO:0030534"(adult behavior)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR005437(Gamma-aminobutyric-acid A receptor, gamma subunit)|interpro:IPR005439(Gamma-aminobutyric-acid A receptor, gamma 2 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|rcsb pdb:6D6T|rcsb pdb:6D6U|rcsb pdb:6HUG|rcsb pdb:6HUJ|rcsb pdb:6HUK - - - figure legend:fig.2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2018/11/05 2019/02/20 rogid:VUUgZBV4Flpu41PyaSqyyoV9+709606 rogid:CxZyFzov1aoSaBHrcHW7Lsv54h09606 rigid:fz/vCH87Z6/dpTtFLb/giscsnrA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51513 uniprotkb:P18507 intact:EBI-726123|uniprotkb:Q6B004|uniprotkb:A8K0S4|uniprotkb:A8K4Q7|uniprotkb:D3DS82|uniprotkb:D3DS81|ensembl:ENSP00000438875 intact:EBI-9008430|uniprotkb:Q6GRL6|uniprotkb:Q6PCC3|uniprotkb:Q9UDB3|uniprotkb:F5HB82|uniprotkb:Q9UN15|ensembl:ENSP00000492125 psi-mi:nova1_human(display_long)|uniprotkb:Neuro-oncological ventral antigen 1(gene name synonym)|uniprotkb:Onconeural ventral antigen 1(gene name synonym)|uniprotkb:Paraneoplastic Ri antigen(gene name synonym)|uniprotkb:Ventral neuron-specific protein 1(gene name synonym)|uniprotkb:NOVA1(gene name)|psi-mi:NOVA1(display_short) psi-mi:gbrg2_human(display_long)|uniprotkb:GABRG2(gene name)|psi-mi:GABRG2(display_short)|uniprotkb:"GABA(A) receptor subunit gamma-2"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2016) pubmed:27733149|imex:IM-26644 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-20822273|imex:IM-26644-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002506.2|refseq:NP_006480.2|refseq:NP_006482.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|interpro:IPR036612|rcsb pdb:1DT4|rcsb pdb:2ANN|rcsb pdb:2ANR|interpro:IPR033086|ensembl:ENSG00000139910(gene)|ensembl:ENST00000539517(transcript) refseq:NP_000807.2|refseq:NP_944493.2|refseq:NP_944494.1|rcsb pdb:6HUP|rcsb pdb:6I53|rcsb pdb:6X3S|rcsb pdb:6X3T|rcsb pdb:6X3U|rcsb pdb:6X3V|rcsb pdb:6X3W|rcsb pdb:6X3X|rcsb pdb:6X3Z|rcsb pdb:6X40|reactome:R-HSA-1236394|reactome:R-HSA-977443|rcsb pdb:6HUO|ensembl:ENSG00000113327(gene)|ensembl:ENST00000639111(transcript)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008503"(benzodiazepine receptor activity)|go:"GO:0009791"(post-embryonic development)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030424"(axon)|go:"GO:0030534"(adult behavior)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR005437(Gamma-aminobutyric-acid A receptor, gamma subunit)|interpro:IPR005439(Gamma-aminobutyric-acid A receptor, gamma 2 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|rcsb pdb:6D6T|rcsb pdb:6D6U|rcsb pdb:6HUG|rcsb pdb:6HUJ|rcsb pdb:6HUK - - - figure legend:fig.2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2018/11/05 2019/02/20 rogid:VUUgZBV4Flpu41PyaSqyyoV9+709606 rogid:CxZyFzov1aoSaBHrcHW7Lsv54h09606 rigid:fz/vCH87Z6/dpTtFLb/giscsnrA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)