#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00747	uniprotkb:Q8N4S9	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938	intact:EBI-6875061|uniprotkb:A1BQX0|uniprotkb:A1BQX1|uniprotkb:A8KA97|uniprotkb:Q96NM9|ensembl:ENSP00000323264|ensembl:ENSP00000480044|ensembl:ENSP00000480068|ensembl:ENSP00000494616	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:mald2_human(display_long)|uniprotkb:MARVELD2(gene name)|psi-mi:MARVELD2(display_short)|uniprotkb:TRIC(gene name synonym)|uniprotkb:Tricellulin(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Sumitomo et al. (2016)	pubmed:26822058|imex:IM-26330	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16745369|imex:IM-26330-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205	refseq:NP_001033692.2|refseq:NP_001231663.1|refseq:XP_005248502.1|refseq:XP_005248503.1|refseq:XP_005248504.1|ensembl:ENSG00000152939(gene)|ensembl:ENSG00000274671(gene)|ensembl:ENST00000325631(transcript)|ensembl:ENST00000614617(transcript)|ensembl:ENST00000622835(transcript)|ensembl:ENST00000645446(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033010"(paranodal junction)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR031177|rcsb pdb:5N7H|rcsb pdb:5N7I|rcsb pdb:5N7K	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/17	2018/01/17	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:WBHGueJq4y54+epedLVPcMvhhOU9606	rigid:yn1kgwxfwvPvfEQbCb27CWnWynQ	false	-	his tag:?-?|sufficient binding region:216-254|mutation decreasing interaction strength:217-217|mutation decreasing interaction strength:252-252|mutation disrupting interaction strength:217-217,252-252	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N4S9	uniprotkb:Q48UF7	intact:EBI-6875061|uniprotkb:A1BQX0|uniprotkb:A1BQX1|uniprotkb:A8KA97|uniprotkb:Q96NM9|ensembl:ENSP00000323264|ensembl:ENSP00000480044|ensembl:ENSP00000480068|ensembl:ENSP00000494616	intact:EBI-16745417|ensemblbacteria:AAX71649	psi-mi:mald2_human(display_long)|uniprotkb:MARVELD2(gene name)|psi-mi:MARVELD2(display_short)|uniprotkb:TRIC(gene name synonym)|uniprotkb:Tricellulin(gene name synonym)	psi-mi:eno_strpm(display_long)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:M28_Spy0535(locus name)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Sumitomo et al. (2016)	pubmed:26822058|imex:IM-26330	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:319701("Streptococcus pyogenes serotype M28 (strain MGAS6180)")|taxid:319701("Streptococcus pyogenes serotype M28 (strain MGAS6180)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16745396|imex:IM-26330-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001033692.2|refseq:NP_001231663.1|refseq:XP_005248502.1|refseq:XP_005248503.1|refseq:XP_005248504.1|ensembl:ENSG00000152939(gene)|ensembl:ENSG00000274671(gene)|ensembl:ENST00000325631(transcript)|ensembl:ENST00000614617(transcript)|ensembl:ENST00000622835(transcript)|ensembl:ENST00000645446(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033010"(paranodal junction)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR031177|rcsb pdb:5N7H|rcsb pdb:5N7I|rcsb pdb:5N7K	ensemblbacteria:AAX71649(transcript)|ensemblbacteria:M28_Spy0535(gene)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|interpro:IPR000941(Enolase)|interpro:IPR036849|interpro:IPR029017|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|refseq:WP_002985288.1	-	-	-	figure legend:Figs. 3, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/17	2018/01/18	rogid:WBHGueJq4y54+epedLVPcMvhhOU9606	rogid:2jU4pZ3SLooiUOTV1qy972OkQMM319701	rigid:+9RzuB9K+4JYjyDwDIkkWPTI9Q8	false	his tag:?-?|sufficient binding region:216-254|mutation decreasing interaction strength:252-252|mutation disrupting interaction strength:217-217,252-252|mutation decreasing interaction strength:217-217	his tag:n-n	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q8N4S9	uniprotkb:P00747	intact:EBI-6875061|uniprotkb:A1BQX0|uniprotkb:A1BQX1|uniprotkb:A8KA97|uniprotkb:Q96NM9|ensembl:ENSP00000323264|ensembl:ENSP00000480044|ensembl:ENSP00000480068|ensembl:ENSP00000494616	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938	psi-mi:mald2_human(display_long)|uniprotkb:MARVELD2(gene name)|psi-mi:MARVELD2(display_short)|uniprotkb:TRIC(gene name synonym)|uniprotkb:Tricellulin(gene name synonym)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Sumitomo et al. (2016)	pubmed:26822058|imex:IM-26330	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16745396|imex:IM-26330-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001033692.2|refseq:NP_001231663.1|refseq:XP_005248502.1|refseq:XP_005248503.1|refseq:XP_005248504.1|ensembl:ENSG00000152939(gene)|ensembl:ENSG00000274671(gene)|ensembl:ENST00000325631(transcript)|ensembl:ENST00000614617(transcript)|ensembl:ENST00000622835(transcript)|ensembl:ENST00000645446(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033010"(paranodal junction)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR031177|rcsb pdb:5N7H|rcsb pdb:5N7I|rcsb pdb:5N7K	refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205	-	-	-	figure legend:Figs. 3, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/17	2018/01/18	rogid:WBHGueJq4y54+epedLVPcMvhhOU9606	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rigid:+9RzuB9K+4JYjyDwDIkkWPTI9Q8	false	his tag:?-?|sufficient binding region:216-254|mutation decreasing interaction strength:252-252|mutation disrupting interaction strength:217-217,252-252|mutation decreasing interaction strength:217-217	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q48UF7	uniprotkb:P00747	intact:EBI-16745417|ensemblbacteria:AAX71649	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938	psi-mi:eno_strpm(display_long)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:M28_Spy0535(locus name)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:"MI:0049"(filter binding)	Sumitomo et al. (2016)	pubmed:26822058|imex:IM-26330	taxid:319701("Streptococcus pyogenes serotype M28 (strain MGAS6180)")|taxid:319701("Streptococcus pyogenes serotype M28 (strain MGAS6180)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16745462|imex:IM-26330-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAX71649(transcript)|ensemblbacteria:M28_Spy0535(gene)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|interpro:IPR000941(Enolase)|interpro:IPR036849|interpro:IPR029017|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|refseq:WP_002985288.1	refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205	-	-	-	figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/17	2018/01/18	rogid:2jU4pZ3SLooiUOTV1qy972OkQMM319701	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rigid:HWKmiJl+WkrIyXiF2/6gWHRJWJA	false	his tag:n-n	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)