#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9CRB9 uniprotkb:Q91VN4 intact:EBI-299847|ensembl:ENSMUSP00000070149 intact:EBI-776230|uniprotkb:Q3UNQ1|uniprotkb:Q9D5I5|uniprotkb:Q9DAM8|ensembl:ENSMUSP00000032172 psi-mi:mic19_mouse(display_long)|uniprotkb:Chchd3(gene name)|psi-mi:Chchd3(display_short)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:Mic19(gene name synonym) psi-mi:mic25_mouse(display_long)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 6(gene name synonym)|uniprotkb:Mic25(gene name synonym)|uniprotkb:Chchd6(gene name)|psi-mi:Chchd6(display_short) psi-mi:"MI:0276"(blue native page) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16721597|imex:IM-26328-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000053768(gene)|ensembl:ENSMUST00000066379(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0019902"(phosphatase binding)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|mint:Q9CRB9|refseq:NP_079612.1 refseq:NP_001161208.1|refseq:NP_079627.3|ensembl:ENSMUSG00000030086(gene)|ensembl:ENSMUST00000032172(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|interpro:IPR042860|mint:Q91VN4 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2018/01/12 2018/01/12 rogid:rxWY2UHnmX3tUiI8/TrJxthCxc010090 rogid:Op64pUsaaQVJ4d+W9vkGMMkgI8810090 rigid:uCu8sBkQMHktNZ8ZaqApcmiJN6A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9CRB9 uniprotkb:Q8CAQ8 intact:EBI-299847|ensembl:ENSMUSP00000070149 intact:EBI-776087|uniprotkb:Q66JS4|uniprotkb:Q7TNE2|uniprotkb:Q8C7V1|uniprotkb:Q8CCI0|uniprotkb:Q8CDA8|uniprotkb:Q9D9F6|ensembl:ENSMUSP00000066181 psi-mi:mic19_mouse(display_long)|uniprotkb:Chchd3(gene name)|psi-mi:Chchd3(display_short)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:Mic19(gene name synonym) psi-mi:mic60_mouse(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:Immt(gene name)|psi-mi:Immt(display_short)|uniprotkb:Mic60(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym) psi-mi:"MI:0276"(blue native page) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16721597|imex:IM-26328-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000053768(gene)|ensembl:ENSMUST00000066379(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0019902"(phosphatase binding)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|mint:Q9CRB9|refseq:NP_079612.1 refseq:NP_083949.2|refseq:NP_001240617.1|refseq:NP_001240610.1|refseq:NP_001240616.1|dip:DIP-32050N|ensembl:ENSMUSG00000052337(gene)|ensembl:ENSMUST00000064062(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|mint:Q8CAQ8|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042407"(cristae formation)|go:"GO:0043209"(myelin sheath)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2018/01/12 2018/01/12 rogid:rxWY2UHnmX3tUiI8/TrJxthCxc010090 rogid:fW23bvuLqjLn5wIOu6ycDsh7O1k10090 rigid:uCu8sBkQMHktNZ8ZaqApcmiJN6A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9CRB9 uniprotkb:Q7TNL9 intact:EBI-299847|ensembl:ENSMUSP00000070149 intact:EBI-16721577|ensembl:ENSMUSP00000059575|ensembl:ENSMUSP00000151675 psi-mi:mic19_mouse(display_long)|uniprotkb:Chchd3(gene name)|psi-mi:Chchd3(display_short)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:Mic19(gene name synonym) psi-mi:q7tnl9_mouse(display_long)|uniprotkb:Chchd10(gene name)|psi-mi:Chchd10(display_short)|uniprotkb:Ndg2(gene name synonym) psi-mi:"MI:0276"(blue native page) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16721597|imex:IM-26328-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000053768(gene)|ensembl:ENSMUST00000066379(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0019902"(phosphatase binding)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|mint:Q9CRB9|refseq:NP_079612.1 refseq:NP_780538.2|refseq:XP_006513056.1|ensembl:ENSMUSG00000049422(gene)|ensembl:ENSMUST00000058906(transcript)|ensembl:ENSMUST00000219839(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061617"(MICOS complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903852"(positive regulation of cristae formation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway) - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2018/01/12 2018/01/12 rogid:rxWY2UHnmX3tUiI8/TrJxthCxc010090 rogid:L4OnAu/wgp/8/QXpBawS8WsHC8c10090 rigid:uCu8sBkQMHktNZ8ZaqApcmiJN6A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WYQ3 uniprotkb:Q9NX63 intact:EBI-16721660|uniprotkb:A8K0J5|ensembl:ENSP00000418428|ensembl:ENSP00000487006 intact:EBI-743375|ensembl:ENSP00000262570 psi-mi:chc10_human(display_long)|uniprotkb:Protein N27C7-4(gene name synonym)|uniprotkb:CHCHD10(gene name)|psi-mi:CHCHD10(display_short)|uniprotkb:C22orf16(gene name synonym) psi-mi:mic19_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:MINOS3(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:MIC19(gene name synonym) psi-mi:"MI:0276"(blue native page) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16721654|imex:IM-26328-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001288268.1|refseq:NP_998885.1|ensembl:ENSG00000250479(gene)|ensembl:ENSG00000273607(gene)|ensembl:ENST00000484558(transcript)|ensembl:ENST00000629095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061617"(MICOS complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903852"(positive regulation of cristae formation)|interpro:IPR010625(CHCH)|reactome:R-HSA-1268020 go:"GO:0008053"(mitochondrial fusion)|refseq:NP_060282.1|refseq:NP_001304106.1|ensembl:ENSG00000106554(gene)|ensembl:ENST00000262570(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|mint:Q9NX63|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0019902"(phosphatase binding) - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-fibroblast)|taxid:9606("Homo sapiens normal diploid fibroblasts (HDF0") - 2018/01/12 2018/01/12 rogid:35vFHwsiBLDq6++7HUVvEoveYaM9606 rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606 rigid:ohnHJUHcfB++JnzvI3Y7NDVXHmU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WYQ3 uniprotkb:Q9BRQ6 intact:EBI-16721660|uniprotkb:A8K0J5|ensembl:ENSP00000418428|ensembl:ENSP00000487006 intact:EBI-2557895|ensembl:ENSP00000290913|uniprotkb:D6R9U0|uniprotkb:D6RIB4|uniprotkb:H8Y0Y7 psi-mi:chc10_human(display_long)|uniprotkb:Protein N27C7-4(gene name synonym)|uniprotkb:CHCHD10(gene name)|psi-mi:CHCHD10(display_short)|uniprotkb:C22orf16(gene name synonym) psi-mi:mic25_human(display_long)|uniprotkb:CHCHD6(gene name)|psi-mi:CHCHD6(display_short)|uniprotkb:CHCM1(gene name synonym)|uniprotkb:Coiled-coil-helix cristae morphology protein 1(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 6(gene name synonym)|uniprotkb:MIC25(gene name synonym) psi-mi:"MI:0276"(blue native page) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16721654|imex:IM-26328-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001288268.1|refseq:NP_998885.1|ensembl:ENSG00000250479(gene)|ensembl:ENSG00000273607(gene)|ensembl:ENST00000484558(transcript)|ensembl:ENST00000629095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061617"(MICOS complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903852"(positive regulation of cristae formation)|interpro:IPR010625(CHCH)|reactome:R-HSA-1268020 refseq:NP_115719.1|refseq:NP_001307539.1|ensembl:ENSG00000159685(gene)|ensembl:ENST00000290913(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|go:"GO:0140275"(MIB complex)|interpro:IPR042860|mint:Q9BRQ6|reactome:R-HSA-8949613 - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-fibroblast)|taxid:9606("Homo sapiens normal diploid fibroblasts (HDF0") - 2018/01/12 2018/01/12 rogid:35vFHwsiBLDq6++7HUVvEoveYaM9606 rogid:6jrzreYX6MJWPfMKh2EKqiEca1s9606 rigid:ohnHJUHcfB++JnzvI3Y7NDVXHmU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WYQ3 uniprotkb:Q16891 intact:EBI-16721660|uniprotkb:A8K0J5|ensembl:ENSP00000418428|ensembl:ENSP00000487006 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 psi-mi:chc10_human(display_long)|uniprotkb:Protein N27C7-4(gene name synonym)|uniprotkb:CHCHD10(gene name)|psi-mi:CHCHD10(display_short)|uniprotkb:C22orf16(gene name synonym) psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:"MI:0276"(blue native page) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16721654|imex:IM-26328-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001288268.1|refseq:NP_998885.1|ensembl:ENSG00000250479(gene)|ensembl:ENSG00000273607(gene)|ensembl:ENST00000484558(transcript)|ensembl:ENST00000629095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061617"(MICOS complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903852"(positive regulation of cristae formation)|interpro:IPR010625(CHCH)|reactome:R-HSA-1268020 refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-fibroblast)|taxid:9606("Homo sapiens normal diploid fibroblasts (HDF0") - 2018/01/12 2018/01/12 rogid:35vFHwsiBLDq6++7HUVvEoveYaM9606 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 rigid:ohnHJUHcfB++JnzvI3Y7NDVXHmU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16891 uniprotkb:Q9NX63 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 intact:EBI-743375|ensembl:ENSP00000262570 psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:mic19_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:MINOS3(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:MIC19(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16724070|imex:IM-26328-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N go:"GO:0008053"(mitochondrial fusion)|refseq:NP_060282.1|refseq:NP_001304106.1|ensembl:ENSG00000106554(gene)|ensembl:ENST00000262570(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|mint:Q9NX63|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0019902"(phosphatase binding) - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-fibroblast)|taxid:9606("Homo sapiens normal diploid fibroblasts (HDF0") - 2018/01/12 2018/01/12 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606 rigid:64EMnIi7k0q5kr45xccTEWVW19E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16891 uniprotkb:Q8WYQ3 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 intact:EBI-16721660|uniprotkb:A8K0J5|ensembl:ENSP00000418428|ensembl:ENSP00000487006 psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:chc10_human(display_long)|uniprotkb:Protein N27C7-4(gene name synonym)|uniprotkb:CHCHD10(gene name)|psi-mi:CHCHD10(display_short)|uniprotkb:C22orf16(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16724070|imex:IM-26328-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N refseq:NP_001288268.1|refseq:NP_998885.1|ensembl:ENSG00000250479(gene)|ensembl:ENSG00000273607(gene)|ensembl:ENST00000484558(transcript)|ensembl:ENST00000629095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061617"(MICOS complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903852"(positive regulation of cristae formation)|interpro:IPR010625(CHCH)|reactome:R-HSA-1268020 - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-fibroblast)|taxid:9606("Homo sapiens normal diploid fibroblasts (HDF0") - 2018/01/12 2018/01/12 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 rogid:35vFHwsiBLDq6++7HUVvEoveYaM9606 rigid:64EMnIi7k0q5kr45xccTEWVW19E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WYQ3 uniprotkb:Q16891 intact:EBI-16721660|uniprotkb:A8K0J5|ensembl:ENSP00000418428|ensembl:ENSP00000487006 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 psi-mi:chc10_human(display_long)|uniprotkb:Protein N27C7-4(gene name synonym)|uniprotkb:CHCHD10(gene name)|psi-mi:CHCHD10(display_short)|uniprotkb:C22orf16(gene name synonym) psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16724094|imex:IM-26328-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001288268.1|refseq:NP_998885.1|ensembl:ENSG00000250479(gene)|ensembl:ENSG00000273607(gene)|ensembl:ENST00000484558(transcript)|ensembl:ENST00000629095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061617"(MICOS complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903852"(positive regulation of cristae formation)|interpro:IPR010625(CHCH)|reactome:R-HSA-1268020 refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/01/12 2018/01/12 rogid:35vFHwsiBLDq6++7HUVvEoveYaM9606 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 rigid:J1wnPhxxm5Qy6hSEL9ACnBh0Uak false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WYQ3 uniprotkb:Q16891 intact:EBI-16721660|uniprotkb:A8K0J5|ensembl:ENSP00000418428|ensembl:ENSP00000487006 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 psi-mi:chc10_human(display_long)|uniprotkb:Protein N27C7-4(gene name synonym)|uniprotkb:CHCHD10(gene name)|psi-mi:CHCHD10(display_short)|uniprotkb:C22orf16(gene name synonym) psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:"MI:0813"(proximity ligation assay) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-16724108|imex:IM-26328-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001288268.1|refseq:NP_998885.1|ensembl:ENSG00000250479(gene)|ensembl:ENSG00000273607(gene)|ensembl:ENST00000484558(transcript)|ensembl:ENST00000629095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061617"(MICOS complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903852"(positive regulation of cristae formation)|interpro:IPR010625(CHCH)|reactome:R-HSA-1268020 refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-fibroblast)|taxid:9606("Homo sapiens normal diploid fibroblasts (HDF0") - 2018/01/12 2018/01/12 rogid:35vFHwsiBLDq6++7HUVvEoveYaM9606 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 rigid:J1wnPhxxm5Qy6hSEL9ACnBh0Uak false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q8WYQ3 uniprotkb:Q9BRQ6 intact:EBI-16721660|uniprotkb:A8K0J5|ensembl:ENSP00000418428|ensembl:ENSP00000487006 intact:EBI-2557895|ensembl:ENSP00000290913|uniprotkb:D6R9U0|uniprotkb:D6RIB4|uniprotkb:H8Y0Y7 psi-mi:chc10_human(display_long)|uniprotkb:Protein N27C7-4(gene name synonym)|uniprotkb:CHCHD10(gene name)|psi-mi:CHCHD10(display_short)|uniprotkb:C22orf16(gene name synonym) psi-mi:mic25_human(display_long)|uniprotkb:CHCHD6(gene name)|psi-mi:CHCHD6(display_short)|uniprotkb:CHCM1(gene name synonym)|uniprotkb:Coiled-coil-helix cristae morphology protein 1(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 6(gene name synonym)|uniprotkb:MIC25(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Genin et al. (2016) imex:IM-26328|pubmed:26666268 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-16724119|imex:IM-26328-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001288268.1|refseq:NP_998885.1|ensembl:ENSG00000250479(gene)|ensembl:ENSG00000273607(gene)|ensembl:ENST00000484558(transcript)|ensembl:ENST00000629095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061617"(MICOS complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090144"(mitochondrial nucleoid organization)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903852"(positive regulation of cristae formation)|interpro:IPR010625(CHCH)|reactome:R-HSA-1268020 refseq:NP_115719.1|refseq:NP_001307539.1|ensembl:ENSG00000159685(gene)|ensembl:ENST00000290913(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|go:"GO:0140275"(MIB complex)|interpro:IPR042860|mint:Q9BRQ6|reactome:R-HSA-8949613 - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-fibroblast)|taxid:9606("Homo sapiens normal diploid fibroblasts (HDF0") - 2018/01/12 2018/01/12 rogid:35vFHwsiBLDq6++7HUVvEoveYaM9606 rogid:6jrzreYX6MJWPfMKh2EKqiEca1s9606 rigid:UF+rJ+K+ml0Fkc8EFWzvJgCoSbo false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)