#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9BR61	uniprotkb:Q9NYU2	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20719993|imex:IM-26405-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032	-	-	-	figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/05/15	2019/02/26	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606	rigid:l4qk1iF1Ngjy5nWmAfHJZvJUHao	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BR61	uniprotkb:Q13557	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-351018|intact:EBI-1642546|uniprotkb:Q52PK4|uniprotkb:Q59G21|uniprotkb:Q8N553|uniprotkb:Q9UGH6|uniprotkb:Q9UQE9|uniprotkb:A8MVS8|ensembl:ENSP00000339740|ensembl:ENSP00000507073	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:kcc2d_human(display_long)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)|uniprotkb:CAMKD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20719993|imex:IM-26405-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	refseq:NP_001212.2|refseq:NP_742112.1|refseq:NP_742113.1|refseq:NP_742125.1|refseq:NP_742126.1|refseq:NP_742127.1|refseq:NP_001308495.1|refseq:NP_001308502.1|refseq:NP_001308509.1|refseq:NP_001308518.1|ensembl:ENSG00000145349(gene)|ensembl:ENST00000342666(transcript)|ensembl:ENST00000683023(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031432"(titin binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901725"(regulation of histone deacetylase activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13557|rcsb pdb:2VN9|rcsb pdb:2W2C|rcsb pdb:2WEL|rcsb pdb:3GP2|rcsb pdb:5VLO|rcsb pdb:6AYW|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|interpro:IPR032710|refseq:XP_011530591.1|refseq:XP_011530593.1|dip:DIP-33129N	-	-	-	figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/05/15	2019/02/26	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI9606	rigid:l4qk1iF1Ngjy5nWmAfHJZvJUHao	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BR61	uniprotkb:P30419	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-5280164|uniprotkb:A8K7C1|uniprotkb:Q9UE09|ensembl:ENSP00000258960|ensembl:ENSP00000468424|ensembl:ENSP00000504192	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt1_human(display_long)|uniprotkb:NMT1(gene name)|psi-mi:NMT1(display_short)|uniprotkb:NMT(gene name synonym)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 1"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20719993|imex:IM-26405-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	refseq:NP_066565.1|ensembl:ENSG00000136448(gene)|ensembl:ENST00000258960(transcript)|ensembl:ENST00000592782(transcript)|ensembl:ENST00000676828(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019107"(myristoyltransferase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0042180"(cellular ketone metabolic process)|go:"GO:1900740"(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:1RXT|rcsb pdb:3IU1|rcsb pdb:3IU2|rcsb pdb:3IWE|rcsb pdb:3JTK|rcsb pdb:4C2Y|rcsb pdb:4C2Z|rcsb pdb:5MU6|rcsb pdb:5NPQ|rcsb pdb:5O6H|rcsb pdb:5O6J|rcsb pdb:5O9S|rcsb pdb:5O9T|rcsb pdb:5O9U|rcsb pdb:5O9V|rcsb pdb:5UUT|rcsb pdb:6EHJ|rcsb pdb:6F56|rcsb pdb:6FZ2|rcsb pdb:6FZ3|rcsb pdb:6FZ5|rcsb pdb:6PAV|rcsb pdb:6QRM|rcsb pdb:6SJZ|rcsb pdb:6SK2|rcsb pdb:6SK3|rcsb pdb:6SK8|rcsb pdb:6SKJ|reactome:R-HSA-162599|reactome:R-HSA-2514859|reactome:R-HSA-75108|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/05/15	2019/02/26	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:eVkADRJp/cg4xIAw0ymeUZ+Vwyk9606	rigid:l4qk1iF1Ngjy5nWmAfHJZvJUHao	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BR61	uniprotkb:O60551	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20719993|imex:IM-26405-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	-	-	-	figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/05/15	2019/02/26	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	rigid:l4qk1iF1Ngjy5nWmAfHJZvJUHao	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O60551	uniprotkb:Q9BR61	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:0728"(gal4 vp16 complementation)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21224552|imex:IM-26405-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Figure 1B, Suplementary fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/05/15	2019/02/27	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rigid:O32YYzEWUyv0wtvXl0vmVlyvIKI	false	necessary binding region:441-498	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:P30419	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-5280164|uniprotkb:A8K7C1|uniprotkb:Q9UE09|ensembl:ENSP00000258960|ensembl:ENSP00000468424|ensembl:ENSP00000504192	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt1_human(display_long)|uniprotkb:NMT1(gene name)|psi-mi:NMT1(display_short)|uniprotkb:NMT(gene name synonym)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 1"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 1(gene name synonym)	psi-mi:"MI:0728"(gal4 vp16 complementation)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21224564|imex:IM-26405-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	refseq:NP_066565.1|ensembl:ENSG00000136448(gene)|ensembl:ENST00000258960(transcript)|ensembl:ENST00000592782(transcript)|ensembl:ENST00000676828(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019107"(myristoyltransferase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0042180"(cellular ketone metabolic process)|go:"GO:1900740"(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:1RXT|rcsb pdb:3IU1|rcsb pdb:3IU2|rcsb pdb:3IWE|rcsb pdb:3JTK|rcsb pdb:4C2Y|rcsb pdb:4C2Z|rcsb pdb:5MU6|rcsb pdb:5NPQ|rcsb pdb:5O6H|rcsb pdb:5O6J|rcsb pdb:5O9S|rcsb pdb:5O9T|rcsb pdb:5O9U|rcsb pdb:5O9V|rcsb pdb:5UUT|rcsb pdb:6EHJ|rcsb pdb:6F56|rcsb pdb:6FZ2|rcsb pdb:6FZ3|rcsb pdb:6FZ5|rcsb pdb:6PAV|rcsb pdb:6QRM|rcsb pdb:6SJZ|rcsb pdb:6SK2|rcsb pdb:6SK3|rcsb pdb:6SK8|rcsb pdb:6SKJ|reactome:R-HSA-162599|reactome:R-HSA-2514859|reactome:R-HSA-75108|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Figure 1B-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/05/15	2019/02/27	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:eVkADRJp/cg4xIAw0ymeUZ+Vwyk9606	rigid:L0pSLfRCrfmsPWGGY+v55zxkUWw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:O60551	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21224596|imex:IM-26405-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	-	-	-	figure legend:Figure 2A, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/05/15	2019/02/27	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	rigid:O32YYzEWUyv0wtvXl0vmVlyvIKI	false	green fluorescent protein tag:n-n|necessary binding region:179-282(IPR020683)	ha tag:n-n|necessary binding region:441-498	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BR61	uniprotkb:O60551	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21224646|imex:IM-26405-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	-	-	-	figure legend:Figure 2B/D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/05/15	2019/02/27	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	rigid:O32YYzEWUyv0wtvXl0vmVlyvIKI	false	ha tag:n-n|necessary binding region:179-282(IPR020683)	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BR61	uniprotkb:O60551	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21224684|imex:IM-26405-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	-	-	-	figure legend:Figure 3A/B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/02/27	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	rigid:O32YYzEWUyv0wtvXl0vmVlyvIKI	false	his tag:?-?|necessary binding region:179-282(IPR020683)	his tag:?-?|sufficient binding region:98-498	1	1	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9BR61	uniprotkb:O60551	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225012|imex:IM-26405-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	-	-	-	figure legend:"Figure 3B (L.H.S.)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/02/27	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	rigid:O32YYzEWUyv0wtvXl0vmVlyvIKI	false	his tag:?-?|necessary binding region:179-282(IPR020683)	his tag:?-?|sufficient binding region:98-498	1	1	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
chebi:"CHEBI:15532"	uniprotkb:Q9BR61	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225038|imex:IM-26405-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	his tag:?-?|mutation increasing interaction rate:106-106|mutation disrupting interaction rate:114-114|mutation disrupting interaction rate:46-46,73-73,95-95,114-114	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:O60551	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225038|imex:IM-26405-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	his tag:?-?|mutation increasing interaction rate:106-106|mutation disrupting interaction rate:114-114|mutation disrupting interaction rate:46-46,73-73,95-95,114-114	his tag:?-?|sufficient binding region:98-498	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:P12931	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225038|imex:IM-26405-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	-	false	his tag:?-?|mutation increasing interaction rate:106-106|mutation disrupting interaction rate:114-114|mutation disrupting interaction rate:46-46,73-73,95-95,114-114	sufficient binding region:2-9	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	chebi:"CHEBI:15532"	intact:EBI-2008615	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225126|imex:IM-26405-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5i|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	uniprotkb:O60551	intact:EBI-2008615	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225126|imex:IM-26405-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5i|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	-	his tag:?-?|sufficient binding region:98-498	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	uniprotkb:P12931	intact:EBI-2008615	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225126|imex:IM-26405-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5i|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	-	false	-	sufficient binding region:2-9	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	uniprotkb:Q9BR61	intact:EBI-2008615	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225925|imex:IM-26405-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5i|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|comment:"In the presence of  the C-terminal deletion mutant of ACBD6, rather than  Wild type ACBD6, addition of C18:2-CoA resulted in a large decrease of activity."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	mutation with no effect:106-106|his tag:?-?|mutation disrupting interaction rate:114-114|mutation disrupting interaction rate:46-46,73-73,95-95,114-114	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15532"	uniprotkb:Q9BR61	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225925|imex:IM-26405-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5i|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|comment:"In the presence of  the C-terminal deletion mutant of ACBD6, rather than  Wild type ACBD6, addition of C18:2-CoA resulted in a large decrease of activity."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	mutation with no effect:106-106|his tag:?-?|mutation disrupting interaction rate:114-114|mutation disrupting interaction rate:46-46,73-73,95-95,114-114	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:O60551	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225925|imex:IM-26405-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5i|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|comment:"In the presence of  the C-terminal deletion mutant of ACBD6, rather than  Wild type ACBD6, addition of C18:2-CoA resulted in a large decrease of activity."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	mutation with no effect:106-106|his tag:?-?|mutation disrupting interaction rate:114-114|mutation disrupting interaction rate:46-46,73-73,95-95,114-114	his tag:?-?|sufficient binding region:98-498	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:P12931	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21225925|imex:IM-26405-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)|interpro:IPR020683	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5i|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|comment:"In the presence of  the C-terminal deletion mutant of ACBD6, rather than  Wild type ACBD6, addition of C18:2-CoA resulted in a large decrease of activity."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	-	false	mutation with no effect:106-106|his tag:?-?|mutation disrupting interaction rate:114-114|mutation disrupting interaction rate:46-46,73-73,95-95,114-114	sufficient binding region:2-9	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15532"	uniprotkb:O60551	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226568|imex:IM-26405-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5,  7A-1, Supplementary fig 1 C/D.|comment:Activity of purified ecNMT2 enzyme was measured by the detection of the release of CoA from C14-CoA in the presence of a synthetic peptide matching the amino terminal myristoylation sequence of c-Src protein.|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	-	his tag:?-?|sufficient binding region:98-498	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15532"	uniprotkb:P12931	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0214"(myristoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226568|imex:IM-26405-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N	go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 4/5,  7A-1, Supplementary fig 1 C/D.|comment:Activity of purified ecNMT2 enzyme was measured by the detection of the release of CoA from C14-CoA in the presence of a synthetic peptide matching the amino terminal myristoylation sequence of c-Src protein.|comment:"carried out in the presence of C14-CoA (myristoyl-CoA)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	-	false	-	sufficient binding region:2-9	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15532"	uniprotkb:Q9BR61	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226620|imex:IM-26405-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	go:"GO:0016746"(acyltransferase activity)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 7A/B|comment:Using the ACBD6 aas 1-178 construct the rate was reduced by ~50%.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	mutation decreasing interaction rate:114-114|his tag:?-?|mutation decreasing interaction rate:106-106	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:O60551	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226620|imex:IM-26405-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0016746"(acyltransferase activity)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 7A/B|comment:Using the ACBD6 aas 1-178 construct the rate was reduced by ~50%.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	mutation decreasing interaction rate:114-114|his tag:?-?|mutation decreasing interaction rate:106-106	his tag:?-?|sufficient binding region:98-498	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15525"	uniprotkb:Q9BR61	intact:EBI-2008688	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:palmitoyl-coa(display_short)|psi-mi:"CHEBI:15525"(display_long)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226620|imex:IM-26405-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	go:"GO:0016746"(acyltransferase activity)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 7A/B|comment:Using the ACBD6 aas 1-178 construct the rate was reduced by ~50%.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	mutation decreasing interaction rate:114-114|his tag:?-?|mutation decreasing interaction rate:106-106	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:P12931	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226620|imex:IM-26405-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N	go:"GO:0016746"(acyltransferase activity)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 7A/B|comment:Using the ACBD6 aas 1-178 construct the rate was reduced by ~50%.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	-	false	mutation decreasing interaction rate:114-114|his tag:?-?|mutation decreasing interaction rate:106-106	sufficient binding region:2-9	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	uniprotkb:Q9BR61	intact:EBI-2008615	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226751|imex:IM-26405-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C|comment:"The mutant Y114A  had no detectable effect on ecNMT2 activity, irrespective of the C18:2-CoA concentrations;however the mutant S106A limited use of C16-CoA by ecNMT2, even when a 10-fold excess of C18:2-CoA was added to the reaction."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	mutation with no effect:114-114|his tag:?-?|mutation decreasing interaction rate:106-106	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15532"	uniprotkb:Q9BR61	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226751|imex:IM-26405-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C|comment:"The mutant Y114A  had no detectable effect on ecNMT2 activity, irrespective of the C18:2-CoA concentrations;however the mutant S106A limited use of C16-CoA by ecNMT2, even when a 10-fold excess of C18:2-CoA was added to the reaction."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	mutation with no effect:114-114|his tag:?-?|mutation decreasing interaction rate:106-106	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:O60551	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226751|imex:IM-26405-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C|comment:"The mutant Y114A  had no detectable effect on ecNMT2 activity, irrespective of the C18:2-CoA concentrations;however the mutant S106A limited use of C16-CoA by ecNMT2, even when a 10-fold excess of C18:2-CoA was added to the reaction."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	mutation with no effect:114-114|his tag:?-?|mutation decreasing interaction rate:106-106	his tag:?-?|sufficient binding region:98-498	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15525"	uniprotkb:Q9BR61	intact:EBI-2008688	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:palmitoyl-coa(display_short)|psi-mi:"CHEBI:15525"(display_long)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226751|imex:IM-26405-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C|comment:"The mutant Y114A  had no detectable effect on ecNMT2 activity, irrespective of the C18:2-CoA concentrations;however the mutant S106A limited use of C16-CoA by ecNMT2, even when a 10-fold excess of C18:2-CoA was added to the reaction."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	mutation with no effect:114-114|his tag:?-?|mutation decreasing interaction rate:106-106	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR61	uniprotkb:P12931	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226751|imex:IM-26405-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C|comment:"The mutant Y114A  had no detectable effect on ecNMT2 activity, irrespective of the C18:2-CoA concentrations;however the mutant S106A limited use of C16-CoA by ecNMT2, even when a 10-fold excess of C18:2-CoA was added to the reaction."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	-	false	mutation with no effect:114-114|his tag:?-?|mutation decreasing interaction rate:106-106	sufficient binding region:2-9	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	chebi:"CHEBI:15532"	intact:EBI-2008615	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21402905|imex:IM-26405-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C|comment:"In the absence of ACBD6 the addition of C18:2-CoA ( linoleoyl-CoA)  did not appear to affect the rate of release of  CoA."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	uniprotkb:O60551	intact:EBI-2008615	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21402905|imex:IM-26405-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C|comment:"In the absence of ACBD6 the addition of C18:2-CoA ( linoleoyl-CoA)  did not appear to affect the rate of release of  CoA."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	-	his tag:?-?|sufficient binding region:98-498	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	chebi:"CHEBI:15525"	intact:EBI-2008615	intact:EBI-2008688	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:palmitoyl-coa(display_short)|psi-mi:"CHEBI:15525"(display_long)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21402905|imex:IM-26405-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C|comment:"In the absence of ACBD6 the addition of C18:2-CoA ( linoleoyl-CoA)  did not appear to affect the rate of release of  CoA."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	uniprotkb:P12931	intact:EBI-2008615	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21402905|imex:IM-26405-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C|comment:"In the absence of ACBD6 the addition of C18:2-CoA ( linoleoyl-CoA)  did not appear to affect the rate of release of  CoA."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	-	false	-	sufficient binding region:2-9	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15532"	uniprotkb:O60551	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21402934|imex:IM-26405-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0016746"(acyltransferase activity)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 7A/Bi|comment:Using the ACBD6 aas 1-178 construct the rate was reduced by ~50%.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	-	his tag:?-?|sufficient binding region:98-498	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15532"	chebi:"CHEBI:15525"	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-2008688	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:palmitoyl-coa(display_short)|psi-mi:"CHEBI:15525"(display_long)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21402934|imex:IM-26405-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	go:"GO:0016746"(acyltransferase activity)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 7A/Bi|comment:Using the ACBD6 aas 1-178 construct the rate was reduced by ~50%.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15532"	uniprotkb:P12931	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:1002"(myristoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0211"(lipid addition)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21402934|imex:IM-26405-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N	go:"GO:0016746"(acyltransferase activity)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)	-	-	figure legend:Figure 7A/Bi|comment:Using the ACBD6 aas 1-178 construct the rate was reduced by ~50%.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/05/24	-	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	-	false	-	sufficient binding region:2-9	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15530"	uniprotkb:Q9BR61	intact:EBI-2008615	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:linoleoyl-coa(display_short)|psi-mi:"CHEBI:15530"(display_long)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226398|imex:IM-26405-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Fig 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/03/01	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	sufficient binding region:1-178|his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15525"	uniprotkb:Q9BR61	intact:EBI-2008688	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:palmitoyl-coa(display_short)|psi-mi:"CHEBI:15525"(display_long)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226406|imex:IM-26405-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:"Fig 6A inset (6C?)"|comment:The text refers to a Figure 6C, which uses C16-CoA; however there is NO Figure 6C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/03/01	-	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	-	false	-	sufficient binding region:1-178|his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15525"	uniprotkb:O60551	intact:EBI-2008688	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:palmitoyl-coa(display_short)|psi-mi:"CHEBI:15525"(display_long)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226415|imex:IM-26405-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	-	-	-	figure legend:Fig 6B -1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/03/01	-	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	-	sufficient binding region:96-498|his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15532"	uniprotkb:O60551	intact:EBI-21226446|chebi:"CHEBI:52969"|chebi:"CHEBI:15218"|chebi:"CHEBI:14637"|chebi:"CHEBI:26898"|chebi:"CHEBI:9475"	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:myristoyl-coa(display_short)|psi-mi:"CHEBI:15532"(display_long)|intact:Myristoyl-CoA(synonym)|intact:"n-C14:0-CoA"(synonym)|intact:"n-C14:0-coenzyme A"(synonym)|intact:S-tetradecanoyl-coenzyme A(synonym)|intact:Tetradecanoyl-CoA(synonym)|intact:"3'-phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(tetradecanoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)"(iupac name)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226437|imex:IM-26405-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	-	-	-	figure legend:Fig 6B -2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/03/01	-	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	-	sufficient binding region:96-498|his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15525"	uniprotkb:O60551	intact:EBI-2008688	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	psi-mi:palmitoyl-coa(display_short)|psi-mi:"CHEBI:15525"(display_long)	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:"MI:1004"(palmitoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0216"(palmitoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226608|imex:IM-26405-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/03/01	-	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	-	false	-	his tag:?-?|sufficient binding region:98-498	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60551	uniprotkb:P12931	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:1004"(palmitoylase assay)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0216"(palmitoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21226608|imex:IM-26405-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N	go:"GO:0016746"(acyltransferase activity)	-	-	figure legend:Figure 7C-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/03/01	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	-	false	his tag:?-?|sufficient binding region:98-498	sufficient binding region:2-9	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60551	uniprotkb:Q9BR61	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567|ensembl:ENSP00000495710	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Soupene et al. (2016)	pubmed:26621918|imex:IM-26405	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21224634|imex:IM-26405-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	refseq:NP_115736.1|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR020683|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|go:"GO:0008289"(lipid binding)|ensembl:ENSG00000230124(gene)|ensembl:ENST00000367595(transcript)|ensembl:ENST00000642319(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:"Figure 2A-2 (Far right image)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/05/15	2019/02/27	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	rigid:O32YYzEWUyv0wtvXl0vmVlyvIKI	false	ha tag:n-n	green fluorescent protein tag:n-n|necessary binding region:179-282(IPR020683)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)