#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-20623174 uniprotkb:Q53F19 - intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623194|imex:IM-26480-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig. 2D|comment:a similar interaction was detected with Human THP-1 lysates.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/17 - rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-20623174 uniprotkb:O60573 - intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623194|imex:IM-26480-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - - - figure legend:Fig. 2D|comment:a similar interaction was detected with Human THP-1 lysates.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/17 - rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-20623174 uniprotkb:Q8BZR9 - intact:EBI-11519402|uniprotkb:Q3TNF4|uniprotkb:Q3TQ96|uniprotkb:Q4G0C3|uniprotkb:Q8BMB1|uniprotkb:Q9CRM6|uniprotkb:Q9CS93|uniprotkb:Q9D0G9|uniprotkb:Q9DBT0|ensembl:ENSMUSP00000021135 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ncbp3_mouse(display_long)|uniprotkb:Ncbp3(gene name)|psi-mi:Ncbp3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623205|imex:IM-26480-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_080094.3|ensembl:ENSMUSG00000020783(gene)|ensembl:ENSMUST00000021135(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig. 2D|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/17 - rogid:E6dFFHdJMCG4pyGbRgLg8gvyxr410090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-20623174 uniprotkb:Q8BMB3 - intact:EBI-398682|uniprotkb:O88503|uniprotkb:Q3UCK2|ensembl:ENSMUSP00000108859 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:if4e2_mouse(display_long)|uniprotkb:Eif4e2(gene name)|psi-mi:Eif4e2(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:Eif4el3(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623205|imex:IM-26480-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_001034259.1|refseq:NP_075803.2|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:Q8BMB3|reactome:R-MMU-1169408|ensembl:ENSMUSG00000026254(gene)|ensembl:ENSMUST00000113233(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body) - - - figure legend:Fig. 2D|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/17 - rogid:SgOe+7l/cbYBuu1+sJqsitN0gSM10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-20623174 uniprotkb:Q53F19 - intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623215|imex:IM-26480-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig. 3D, 3H|comment:"To study whether NCBP3 has the ability to directly bind capped RNA, we generated recombinant NCBP3 in Escherichia coli. Both, the full-length protein and an N-terminal cleavage fragment of NCBP3 precipitated with RNA in a cap-dependent manner (Fig. 3d)."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/17 - rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - false biotin tag:?-?|uncategorized protein modification:?-? his tag:n-n|mutation with no effect:134-134|mutation disrupting interaction strength:155-158 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:50210" uniprotkb:Q53F19 intact:EBI-1788056 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 psi-mi:7-methyl-gtp(display_short)|psi-mi:"CHEBI:50210"(display_long) psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626803|imex:IM-26480-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig. 2E|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:50210" uniprotkb:Q09161 intact:EBI-1788056 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:7-methyl-gtp(display_short)|psi-mi:"CHEBI:50210"(display_long) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626803|imex:IM-26480-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - - figure legend:Fig. 2E|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 - false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:50210" uniprotkb:Q53F19 intact:EBI-1788056 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 psi-mi:7-methyl-gtp(display_short)|psi-mi:"CHEBI:50210"(display_long) psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626810|imex:IM-26480-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig. 3E|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - false - maltose binding protein tag:n-n|his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:50210" uniprotkb:Q53F19 intact:EBI-1788056 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 psi-mi:7-methyl-gtp(display_short)|psi-mi:"CHEBI:50210"(display_long) psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626839|imex:IM-26480-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0496"(bait) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig. 4E|comment:"Consistent with the presence of two CBCs, NCBP1 could be recovered from m7GTP beads in the absence of either NCBP2 or NCBP3 (Fig. 4e). However, in the absence of NCBP2 and -3, NCBP1 binding to m7GTP beads was markedly impaired, indicating that in mammalian cells NCBP1 requires either NCBP2 or NCBP3 for cap-RNA association."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:50210" uniprotkb:P52298 intact:EBI-1788056 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 psi-mi:7-methyl-gtp(display_short)|psi-mi:"CHEBI:50210"(display_long) psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626839|imex:IM-26480-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0496"(bait) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N - - - figure legend:Fig. 4E|comment:"Consistent with the presence of two CBCs, NCBP1 could be recovered from m7GTP beads in the absence of either NCBP2 or NCBP3 (Fig. 4e). However, in the absence of NCBP2 and -3, NCBP1 binding to m7GTP beads was markedly impaired, indicating that in mammalian cells NCBP1 requires either NCBP2 or NCBP3 for cap-RNA association."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 - false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:50210" uniprotkb:O60573 intact:EBI-1788056 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:7-methyl-gtp(display_short)|psi-mi:"CHEBI:50210"(display_long) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626839|imex:IM-26480-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - - - figure legend:Fig. 4E|comment:"Consistent with the presence of two CBCs, NCBP1 could be recovered from m7GTP beads in the absence of either NCBP2 or NCBP3 (Fig. 4e). However, in the absence of NCBP2 and -3, NCBP1 binding to m7GTP beads was markedly impaired, indicating that in mammalian cells NCBP1 requires either NCBP2 or NCBP3 for cap-RNA association."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 - false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:50210" uniprotkb:Q09161 intact:EBI-1788056 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:7-methyl-gtp(display_short)|psi-mi:"CHEBI:50210"(display_long) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626839|imex:IM-26480-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - - figure legend:Fig. 4E|comment:"Consistent with the presence of two CBCs, NCBP1 could be recovered from m7GTP beads in the absence of either NCBP2 or NCBP3 (Fig. 4e). However, in the absence of NCBP2 and -3, NCBP1 binding to m7GTP beads was markedly impaired, indicating that in mammalian cells NCBP1 requires either NCBP2 or NCBP3 for cap-RNA association."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 - false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53F19 intact:EBI-20623174 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 - psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:"MI:1247"(microscale thermophoresis) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-20623235|imex:IM-26480-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 genbank identifier:JQ316196(see-also) - - - figure legend:Fig. 3g|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:15.8x10^-6 ~0.84(molar) 2018/07/17 2018/07/17 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - - false his tag:n-n|sufficient binding region:1-282 biotin tag:?-?|uncategorized protein modification:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53F19 uniprotkb:P56270 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1809742|uniprotkb:A8QJL9|uniprotkb:Q15703|uniprotkb:Q99443|uniprotkb:H3BQD6|uniprotkb:G5E927|uniprotkb:Q8NFN7|uniprotkb:C6G496|ensembl:ENSP00000313362 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:maz_human(display_long)|uniprotkb:Transcription factor Zif87(gene name synonym)|uniprotkb:Zinc finger protein 801(gene name synonym)|uniprotkb:MAZ(gene name)|psi-mi:MAZ(display_short)|uniprotkb:Purine-binding transcription factor(gene name synonym)|uniprotkb:Pur-1(gene name synonym)|uniprotkb:ZF87(gene name synonym)|uniprotkb:ZNF801(gene name synonym)|uniprotkb:Serum amyloid A-activating factor-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_002374.2|refseq:NP_001036004.1|refseq:NP_001263205.1|refseq:NP_001263204.1|ensembl:ENSG00000103495(gene)|ensembl:ENST00000322945(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P56270 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:zuCDXhF2wr8gmTyjBNse9kVUqSw9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q14011 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-538850|uniprotkb:B4E2X2|intact:EBI-10980353|uniprotkb:B3KT17|ensembl:ENSP00000322887|ensembl:ENSP00000465779|ensembl:ENSP00000466110|ensembl:ENSP00000466207|ensembl:ENSP00000468788 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:cirbp_human(display_long)|uniprotkb:Glycine-rich RNA-binding protein CIRP(gene name synonym)|uniprotkb:A18 hnRNP(gene name synonym)|uniprotkb:CIRBP(gene name)|psi-mi:CIRBP(display_short)|uniprotkb:A18HNRNP(gene name synonym)|uniprotkb:CIRP(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001271.1|refseq:XP_006722700.1|refseq:NP_001287744.1|refseq:NP_001287758.1|ensembl:ENSG00000099622(gene)|ensembl:ENST00000320936(transcript)|ensembl:ENST00000585630(transcript)|ensembl:ENST00000586472(transcript)|ensembl:ENST00000588030(transcript)|ensembl:ENST00000588090(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009409"(response to cold)|go:"GO:0009411"(response to UV)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030371"(translation repressor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034278|interpro:IPR035979|mint:Q14011|rcsb pdb:1X5S|rcsb pdb:5TBX - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:nm6/8k5Pw1AnoXsSw9cazJkL49U9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q8N0Z6 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-9526213|uniprotkb:A8MQ18|uniprotkb:Q96HF9|ensembl:ENSP00000258821 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ttc5_human(display_long)|uniprotkb:TTC5(gene name)|psi-mi:TTC5(display_short)|uniprotkb:Stress-responsive activator of p300(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_612385.2|ensembl:ENSG00000136319(gene)|ensembl:ENST00000258821(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032076|interpro:IPR038645|mint:Q8N0Z6|rcsb pdb:2XVS|rcsb pdb:6T59|reactome:R-HSA-6804760 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:rX19ztJC6lUHDMJuKotMBXMGrcU9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q8N8U2 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-8467076|uniprotkb:Q7Z5I8|intact:MINT-8417653|ensembl:ENSP00000476295 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:cdyl2_human(display_long)|uniprotkb:CDYL2(gene name)|psi-mi:CDYL2(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_689555.2|rcsb pdb:5JJZ|rcsb pdb:6V2D|rcsb pdb:6V2H|rcsb pdb:6V3N|rcsb pdb:6V8W|ensembl:ENSG00000166446(gene)|ensembl:ENST00000570137(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0035064"(methylated histone binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR029045|mint:Q8N8U2|rcsb pdb:2MJ8|rcsb pdb:4HAE - - comment:mint|comment:homomint figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:2rIDC41LBqQGKkDghE8VAChJorM9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P35052 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-8307554|ensembl:ENSP00000264039|intact:UNK-5376584|uniprotkb:Q53QM4|intact:UNK-5431308|uniprotkb:B3KTD1 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:gpc1_human(display_long)|uniprotkb:GPC1(gene name)|psi-mi:GPC1(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000063660(gene)|ensembl:ENST00000264039(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0016477"(cell migration)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032288"(myelin assembly)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043236"(laminin binding)|go:"GO:0045121"(membrane raft)|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-376176|reactome:R-HSA-4420332|reactome:R-HSA-975634|go:"GO:0045202"(synapse)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1905475"(regulation of protein localization to membrane)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR001863(Glypican)|interpro:IPR015502(Glypican1)|interpro:IPR019803|mint:P35052|rcsb pdb:4ACR|rcsb pdb:4AD7|rcsb pdb:4BWE|rcsb pdb:4YWT|reactome:R-HSA-1971475|reactome:R-HSA-2022928|refseq:NP_002072.2 - - function:Cell surface proteoglycan that bears heparan sulfate|comment:mint figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:ycuKz8cHA1TlfV2XkBz+onEEwyw9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O95373 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9UH99 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q8NEM0 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1565483|uniprotkb:Q66GU1|uniprotkb:Q9H9C7|uniprotkb:A0A075B6F8|uniprotkb:B4DWW2|uniprotkb:E9PH63|uniprotkb:E9PGU5|ensembl:ENSP00000342924|ensembl:ENSP00000493874 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:mcph1_human(display_long)|uniprotkb:MCPH1(gene name)|psi-mi:MCPH1(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001166045.1|refseq:NP_001166046.1|refseq:NP_078872.2|refseq:NP_001308971.1|refseq:NP_001308972.1|refseq:NP_001308974.1|dip:DIP-39802N|ensembl:ENSG00000147316(gene)|ensembl:ENSG00000285262(gene)|ensembl:ENST00000344683(transcript)|ensembl:ENST00000647051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060348"(bone development)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR001357(BRCT)|interpro:IPR022047|interpro:IPR029504|interpro:IPR036420|mint:Q8NEM0|rcsb pdb:2WT8|rcsb pdb:3KTF|rcsb pdb:3PA6|rcsb pdb:3SHT|rcsb pdb:3SHV|rcsb pdb:3SZM|rcsb pdb:3T1N|rcsb pdb:3U3Z|rcsb pdb:7C5D|reactome:R-HSA-2299718 - - crc64:D17961B94EC240A3 figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:EL5tbrvv9UfYCOmG+7yweFO2zH49606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q32M45 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-20623289|uniprotkb:Q8NAJ0|uniprotkb:Q8NB39|uniprotkb:Q8NB53|ensembl:ENSP00000376703|ensembl:ENSP00000469449|ensembl:ENSP00000470039|ensembl:ENSP00000471431 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ano4_human(display_long)|uniprotkb:Transmembrane protein 16D(gene name synonym)|uniprotkb:ANO4(gene name)|psi-mi:ANO4(display_short)|uniprotkb:TMEM16D(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001273544.1|refseq:NP_001273545.1|refseq:NP_849148.2|refseq:XP_011536216.1|refseq:XP_016874297.1|refseq:XP_016874298.1|refseq:XP_016874299.1|ensembl:ENSG00000151572(gene)|ensembl:ENSG00000262139(gene)|ensembl:ENST00000392977(transcript)|ensembl:ENST00000570509(transcript)|ensembl:ENST00000573650(transcript)|ensembl:ENST00000575847(transcript)|go:"GO:0005229"(intracellular calcium activated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061589"(calcium activated phosphatidylserine scrambling)|go:"GO:0061590"(calcium activated phosphatidylcholine scrambling)|go:"GO:0061591"(calcium activated galactosylceramide scrambling)|go:"GO:1902476"(chloride transmembrane transport)|interpro:IPR007632(Protein of unknown function DUF590)|interpro:IPR031293|interpro:IPR032394|reactome:R-HSA-2672351 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:BhAR3vDT1JYk+wtCHoUCi1e4Ue09606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q6L8Q7 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2515865|ensembl:ENSP00000309142|uniprotkb:Q8IYU3|uniprotkb:Q8NDU2|uniprotkb:Q8TE78|uniprotkb:B4DTU8 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:pde12_human(display_long)|uniprotkb:PDE12(gene name)|psi-mi:PDE12(display_short)|uniprotkb:Mitochondrial deadenylase(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENST00000311180(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000958"(mitochondrial mRNA catabolic process)|go:"GO:0004527"(exonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0034611"(oligoribonucleotidase activity)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|ensembl:ENSG00000174840(gene)|interpro:IPR036691|mint:Q6L8Q7|rcsb pdb:4Z0V|rcsb pdb:4Z2B|rcsb pdb:4ZKF|reactome:R-HSA-8983711|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|refseq:NP_808881.3 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:P2ALFhSP4Qnqnd08vmkOcVoXe/I9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q6PJT7 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-740660|uniprotkb:B4DXU8|uniprotkb:B4DZW7|ensembl:ENSP00000251038|uniprotkb:A8MY46|uniprotkb:Q6MZU4|uniprotkb:Q6PJ32|uniprotkb:Q6PUI6|uniprotkb:Q6PUI8|uniprotkb:Q86TQ5|uniprotkb:Q86TW0|uniprotkb:Q86TW1|uniprotkb:Q8NCZ3|uniprotkb:Q8TDE2|uniprotkb:Q9HAC9|uniprotkb:Q9Y5A0|uniprotkb:Q8NCT6|intact:EBI-2857849|uniprotkb:B4E2H4|uniprotkb:G3V5R4 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:zc3he_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-37(gene name synonym)|uniprotkb:ZC3H14(gene name)|psi-mi:ZC3H14(display_short)|uniprotkb:Mammalian suppressor of tau pathology-2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001153575.1|refseq:NP_001153576.1|refseq:NP_079100.2|refseq:NP_997543.1|refseq:NP_997544.1|refseq:NP_997545.2|ensembl:ENSG00000100722(gene)|ensembl:ENST00000251038(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR040366|refseq:XP_005268125.1|refseq:NP_001313236.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:X2bh/uBtNVh/Wy30Sk+M3ijrZoM9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q02224 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P31150 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-946999|uniprotkb:P50394|uniprotkb:Q7Z2G6|uniprotkb:Q7Z2G9|uniprotkb:Q7Z2H5|uniprotkb:Q7Z2I6|uniprotkb:Q6FG50|ensembl:ENSP00000394071 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:gdia_human(display_long)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:OPHN2(gene name synonym)|uniprotkb:RABGDIA(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 1(gene name synonym)|uniprotkb:Oligophrenin-2(gene name synonym)|uniprotkb:Protein XAP-4(gene name synonym)|uniprotkb:GDIL(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001484.1|ensembl:ENSG00000203879(gene)|ensembl:ENST00000447750(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0051592"(response to calcium ion)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P31150|reactome:R-HSA-8876198 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:bE8RgEdzf7V/T+hWdGJkM9WM0yI9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q5DJT8 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-11064777|uniprotkb:Q5JRH3|ensembl:ENSP00000474632|ensembl:ENSP00000483619 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ct452_human(display_long)|uniprotkb:CT45A2(gene name)|psi-mi:CT45A2(display_short)|uniprotkb:CT45-2(gene name synonym)|uniprotkb:Cancer/testis antigen 45-2(gene name synonym)|uniprotkb:Cancer/testis antigen 45A2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001278464.1|refseq:NP_001278469.1|refseq:NP_689795.4|refseq:XP_006724846.1|refseq:XP_006724859.1|refseq:XP_006724862.1|refseq:XP_011529543.1|refseq:XP_011529691.1|refseq:NP_001308200.1|ensembl:ENSG00000271449(gene)|ensembl:ENST00000605791(transcript)|ensembl:ENST00000612907(transcript)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR029307 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:oJ5qFXTBCXlZW4PS1HrSyrS8iaQ9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9UER7 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P48668 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2564105|uniprotkb:A1L4L5|uniprotkb:P48666|uniprotkb:Q2TAZ9|uniprotkb:Q7RTN9|ensembl:ENSP00000252250 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:k2c6c_human(display_long)|uniprotkb:Type-II keratin Kb12(gene name synonym)|uniprotkb:KRT6C(gene name)|psi-mi:KRT6C(display_short)|uniprotkb:KRT6E(gene name synonym)|uniprotkb:Cytokeratin-6C(gene name synonym)|uniprotkb:Keratin-6C(gene name synonym)|uniprotkb:Cytokeratin-6E(gene name synonym)|uniprotkb:Keratin K6h(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_775109.2|ensembl:ENSG00000170465(gene)|ensembl:ENST00000252250(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:/fw0ybueYYwWQbVao1bTQkgmQ789606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O75940 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1052641|uniprotkb:Q5T3K6|uniprotkb:D3DRB1|uniprotkb:B2RA27|ensembl:ENSP00000358605|ensembl:ENSP00000358616 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:spf30_human(display_long)|uniprotkb:SMN-related protein(gene name synonym)|uniprotkb:30 kDa splicing factor SMNrp(gene name synonym)|uniprotkb:Survival motor neuron domain-containing protein 1(gene name synonym)|uniprotkb:SMNDC1(gene name)|psi-mi:SMNDC1(display_short)|uniprotkb:SMNR(gene name synonym)|uniprotkb:SPF30(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_005862.1|ensembl:ENSG00000119953(gene)|ensembl:ENST00000369592(transcript)|ensembl:ENST00000369603(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:O75940|go:"GO:0006915"(apoptotic process)|rcsb pdb:4A4F|rcsb pdb:4A4H|reactome:R-HSA-72163 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:hrp2pNu/wpfPdN/3qdDSwqz1t6Q9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:J3QSV6 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-20623278|ensembl:ENSP00000347897 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:j3qsv6_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000171490(gene)|ensembl:ENST00000355674(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:Y9Ddf0AKzakeZ5SF/lAIcBPoxmo9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O95619 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-399269|uniprotkb:Q9NQD0|ensembl:ENSP00000247843 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:yets4_human(display_long)|uniprotkb:YEATS4(gene name)|psi-mi:YEATS4(display_short)|uniprotkb:Glioma-amplified sequence 41(gene name synonym)|uniprotkb:NuMA-binding protein 1(gene name synonym)|uniprotkb:GAS41(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_006521.1|refseq:NP_001287879.1|ensembl:ENSG00000127337(gene)|ensembl:ENST00000247843(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0140030"(modification-dependent protein binding)|interpro:IPR005033(YEATS)|interpro:IPR038704|rcsb pdb:5R68|rcsb pdb:5R69|rcsb pdb:5VNA|rcsb pdb:5VNB|rcsb pdb:5XTZ|rcsb pdb:5Y8V|reactome:R-HSA-3214847|reactome:R-HSA-8866907 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:JCwzX52Km5sXp5bi9PZvOW4HYjM9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q7L590 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-374912|uniprotkb:Q3MIR3|uniprotkb:Q7LD55|uniprotkb:Q96GX4|uniprotkb:Q96NB6|uniprotkb:Q9H0D7|uniprotkb:Q9H3P9|uniprotkb:Q9P177|uniprotkb:A8K9I6|uniprotkb:B7ZKZ8|ensembl:ENSP00000418268 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:mcm10_human(display_long)|uniprotkb:MCM10(gene name)|psi-mi:MCM10(display_short)|uniprotkb:PRO2249(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019899"(enzyme binding)|ensembl:ENSG00000065328(gene)|ensembl:ENST00000484800(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|interpro:IPR015411(Mcm10 replication factor)|interpro:IPR040184|mint:Q7L590|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|reactome:R-HSA-176187|go:"GO:0006270"(DNA replication initiation)|reactome:R-HSA-68962|refseq:XP_011517840.1|refseq:NP_060988.3|refseq:NP_877428.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:dh8NvxigVGynDZaLYKGrvBu5XQ09606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q96GX9 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q6IEG0 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2876632|uniprotkb:Q5THM2|uniprotkb:Q96MK1|uniprotkb:Q5THM1|uniprotkb:Q14C91|uniprotkb:Q5T339|uniprotkb:A8K8P4|ensembl:ENSP00000339834 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:snr48_human(display_long)|uniprotkb:SNRNP48(gene name)|psi-mi:SNRNP48(display_short)|uniprotkb:C6orf151(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_689764.3|ensembl:ENSG00000168566(gene)|ensembl:ENST00000342415(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR022776|interpro:IPR032845|interpro:IPR036236|rcsb pdb:2VY4|rcsb pdb:2VY5|reactome:R-HSA-72165 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:xKzG44rRn2jI0igYZDuk2eP7+Eg9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9BY42 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1045669|uniprotkb:Q9BYL7|uniprotkb:Q9HCV9|uniprotkb:Q9NX29|uniprotkb:Q9NZZ8|uniprotkb:Q9P002|uniprotkb:Q9UHW3|uniprotkb:E1P5Z9|ensembl:ENSP00000349906 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:rtf2_human(display_long)|uniprotkb:RTF2(gene name)|psi-mi:RTF2(display_short)|uniprotkb:C20orf43(gene name synonym)|uniprotkb:RTFDC1(gene name synonym)|uniprotkb:Replication termination factor 2 domain-containing protein 1(gene name synonym)|uniprotkb:AD-007(orf name)|uniprotkb:CDA05(orf name)|uniprotkb:HSPC164(orf name)|uniprotkb:HSPC169(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001269964.1|refseq:NP_001269965.1|refseq:NP_001269966.1|refseq:NP_057491.2|ensembl:ENSG00000022277(gene)|go:"GO:0003677"(DNA binding)|ensembl:ENST00000357348(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0071171"(site-specific DNA replication termination at RTS1 barrier)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1902979"(mitotic DNA replication termination)|interpro:IPR006735(Protein of unknown function DUF602)|interpro:IPR027799 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:eh/6sc/MIM9QOLgd0NfZaezJ7ek9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P61326 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-299134|ensembl:ENSP00000360525|uniprotkb:O35169|uniprotkb:P50606|uniprotkb:Q5SW69|uniprotkb:B2R5A2|uniprotkb:B1ARP8 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:mgn_human(display_long)|uniprotkb:MAGOH(gene name)|psi-mi:MAGOH(display_short)|uniprotkb:MAGOHA(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000162385(gene)|ensembl:ENST00000371470(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61326|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_002361.1|dip:DIP-33069N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:QwhNt2LtYudXCggVAqBsZm/hWAA9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q96IZ7 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-712189|uniprotkb:A8K2R9|uniprotkb:Q96QK2|uniprotkb:Q9NZE5|intact:EBI-2557608|ensembl:ENSP00000295930|ensembl:ENSP00000420150|ensembl:ENSP00000481697 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:rsrc1_human(display_long)|uniprotkb:RSRC1(gene name)|psi-mi:RSRC1(display_short)|uniprotkb:BM-011(orf name)|uniprotkb:SRRP53(gene name synonym)|uniprotkb:Arginine/serine-rich coiled-coil protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_057709.2|refseq:NP_001258763.1|refseq:NP_001258767.1|ensembl:ENSG00000174891(gene)|ensembl:ENST00000295930(transcript)|ensembl:ENST00000480820(transcript)|ensembl:ENST00000611884(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046677"(response to antibiotic)|interpro:IPR034604|mint:Q96IZ7 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:B7EPA0m7YFHe27lcDT3UiXf/hMk9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q8TF76 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1237328|uniprotkb:Q5U5K3|uniprotkb:Q96MN1|uniprotkb:Q9BXS7|ensembl:ENSP00000325290 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:hasp_human(display_long)|uniprotkb:HASPIN(gene name)|psi-mi:HASPIN(display_short)|uniprotkb:GSG2(gene name synonym)|uniprotkb:Germ cell-specific gene 2 protein(gene name synonym)|uniprotkb:H-haspin(gene name synonym)|uniprotkb:Haploid germ cell-specific nuclear protein kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_114171.2|dip:DIP-38174N|ensembl:ENSG00000177602(gene)|ensembl:ENST00000325418(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|interpro:IPR024604|rcsb pdb:2VUW|rcsb pdb:2WB8|rcsb pdb:3DLZ|rcsb pdb:3E7V|rcsb pdb:3F2N|rcsb pdb:3FMD|rcsb pdb:3IQ7|rcsb pdb:4OUC|rcsb pdb:4QTC|rcsb pdb:5HTB|rcsb pdb:5HTC|rcsb pdb:6G34|rcsb pdb:6G35|rcsb pdb:6G36|rcsb pdb:6G37|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|rcsb pdb:6G38|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0072354"("histone kinase activity (H3-T3 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000751"(histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:6G39|rcsb pdb:6G3A|rcsb pdb:6Z56|rcsb pdb:6Z57|rcsb pdb:6Z58|rcsb pdb:6Z59|rcsb pdb:6Z5A|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6Z5B|rcsb pdb:6Z5C|rcsb pdb:6Z5D|rcsb pdb:6Z5E|rcsb pdb:7AVQ - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:oEsn4Mdj1ffEam0s7mvekInDHO49606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O00148 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P49756 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q10589 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P31431 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-3913237|uniprotkb:Q16833|uniprotkb:O00773|uniprotkb:Q53FN9|uniprotkb:Q6FGN3|ensembl:ENSP00000361818 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:sdc4_human(display_long)|uniprotkb:SDC4(gene name)|psi-mi:SDC4(display_short)|uniprotkb:Amphiglycan(gene name synonym)|uniprotkb:Ryudocan core protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_002990.2|ensembl:ENSG00000124145(gene)|ensembl:ENST00000372733(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016477"(cell migration)|go:"GO:0042060"(wound healing)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|rcsb pdb:1EJP|rcsb pdb:1EJQ|rcsb pdb:1OBY|rcsb pdb:1YBO|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3000170|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634|dip:DIP-29945N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:ggGFQ0PE+rGXSk3dHtQCgHwSjjk9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P34741 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1172957|uniprotkb:Q9H6V1|uniprotkb:B3KQA3|ensembl:ENSP00000307046|uniprotkb:Q6PIS6 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:sdc2_human(display_long)|uniprotkb:SDC2(gene name)|psi-mi:SDC2(display_short)|uniprotkb:HSPG1(gene name synonym)|uniprotkb:Fibroglycan(gene name synonym)|uniprotkb:Heparan sulfate proteoglycan core protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_002989.2|reactome:R-HSA-975634|reactome:R-HSA-8957275|ensembl:ENSG00000169439(gene)|ensembl:ENST00000302190(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031201|mint:P34741|rcsb pdb:6ITH|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3000170|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-381426|reactome:R-HSA-3928662|reactome:R-HSA-4420332|dip:DIP-29943N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:dUYGfiWzMHbYLZdV/ibV6RmeYUA9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P83916 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P63104 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O75400 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-473291|uniprotkb:O43856|uniprotkb:O75404|uniprotkb:Q8TBQ1|uniprotkb:Q9H782|uniprotkb:Q9NWU9|uniprotkb:Q9P0Q2|uniprotkb:Q9Y5A8 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:pr40a_human(display_long)|uniprotkb:Formin-binding protein 3(gene name synonym)|uniprotkb:Formin-binding protein 11(gene name synonym)|uniprotkb:Huntingtin-interacting protein A(gene name synonym)|uniprotkb:Huntingtin yeast partner A(gene name synonym)|uniprotkb:Fas ligand-associated factor 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-6(gene name synonym)|uniprotkb:HSPC225(orf name)|uniprotkb:PRPF40A(gene name)|psi-mi:PRPF40A(display_short)|uniprotkb:FLAF1(gene name synonym)|uniprotkb:HYPA(gene name synonym)|uniprotkb:FBP11(gene name synonym)|uniprotkb:FNBP3(gene name synonym)|uniprotkb:HIP10(gene name synonym)|uniprotkb:Huntingtin-interacting protein 10(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005685"(U1 snRNP)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0051301"(cell division)|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:1UZC|rcsb pdb:1YWI|rcsb pdb:1YWJ|rcsb pdb:1ZR7|rcsb pdb:2CQN|rcsb pdb:2DYF|rcsb pdb:2KZG|rcsb pdb:2L5F|rcsb pdb:2L9V|rcsb pdb:2LKS|reactome:R-HSA-72163|refseq:NP_060362.3|interpro:IPR002713(FF)|interpro:IPR001202(WW/Rsp5/WWP)|mint:O75400|interpro:IPR036020|interpro:IPR036517|interpro:IPR039726 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:XgnBshjHK5u08HROtUS9Zr2Ot809606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q8TDD1 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:VzxEkRaOIND08jGJk3yyoztesjo9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P09603 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2872294|ensembl:ENSP00000327513|ensembl:ENSP00000358817|uniprotkb:Q14806|uniprotkb:Q5VVF4|uniprotkb:Q14086|uniprotkb:A8K6J5|uniprotkb:Q13130|uniprotkb:Q9UQR8|uniprotkb:Q5VVF3 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:csf1_human(display_long)|uniprotkb:CSF1(gene name)|psi-mi:CSF1(display_short)|uniprotkb:Lanimostim(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000184371(gene)|ensembl:ENST00000329608(transcript)|ensembl:ENST00000369802(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002158"(osteoclast proliferation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0005125"(cytokine activity)|go:"GO:0005157"(macrophage colony-stimulating factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010743"(regulation of macrophage derived foam cell differentiation)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032946"(positive regulation of mononuclear cell proliferation)|go:"GO:0038145"(macrophage colony-stimulating factor signaling pathway)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042117"(monocyte activation)|go:"GO:0042488"(positive regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060611"(mammary gland fat development)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902228"(positive regulation of macrophage colony-stimulating factor signaling pathway)|go:"GO:1904141"(positive regulation of microglial cell migration)|go:"GO:1905523"(positive regulation of macrophage migration)|interpro:IPR008001(Macrophage colony stimulating factor-1)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HMC|rcsb pdb:3UEZ|rcsb pdb:3UF2|rcsb pdb:4ADF|rcsb pdb:4FA8|rcsb pdb:4WRL|rcsb pdb:4WRM|rcsb pdb:5LXF|reactome:R-HSA-381426|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-8957275|go:"GO:1990682"(CSF1-CSF1R complex)|refseq:NP_000748.3|refseq:NP_757349.1|refseq:NP_757351.1|refseq:NP_757350.1|dip:DIP-41860N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:YSg7hoJM9d3lvDoswhhVkvt0D8I9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q86WX3 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-4479407|uniprotkb:B0QY96|uniprotkb:Q5JZA1|ensembl:ENSP00000333948 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:aros_human(display_long)|uniprotkb:RPS19BP1(gene name)|psi-mi:RPS19BP1(display_short)|uniprotkb:AROS(gene name synonym)|uniprotkb:40S ribosomal protein S19-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_919307.1|ensembl:ENSG00000187051(gene)|ensembl:ENST00000334678(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0019899"(enzyme binding)|interpro:IPR023262|mint:Q86WX3|reactome:R-HSA-3371453 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:A2pEtlH5IGyyVVhqX9EvlHE8XTM9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q00403 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-389564|uniprotkb:A8K1A7|uniprotkb:Q5JS30|ensembl:ENSP00000359531 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:tf2b_human(display_long)|uniprotkb:GTF2B(gene name)|psi-mi:GTF2B(display_short)|uniprotkb:TF2B(gene name synonym)|uniprotkb:TFIIB(gene name synonym)|uniprotkb:General transcription factor TFIIB(gene name synonym)|uniprotkb:S300-II(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001505.1|ensembl:ENSG00000137947(gene)|ensembl:ENST00000370500(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005694"(chromosome)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019083"(viral transcription)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000812(Transcription factor TFIIB related)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR013150(Transcription factor TFIIB, cyclin-related)|interpro:IPR013763(Cyclin-related)|interpro:IPR023486|interpro:IPR036915|mint:Q00403|rcsb pdb:1C9B|rcsb pdb:1DL6|rcsb pdb:1RLY|rcsb pdb:1RO4|rcsb pdb:1TFB|rcsb pdb:1VOL|rcsb pdb:2PHG|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5WH1|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|dip:DIP-1077N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:mVGHi0jBibSFHpBrVTGHnRm4gXw9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q13352 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-712105|ensembl:ENSP00000271002|uniprotkb:Q13353|uniprotkb:Q5RJ42|uniprotkb:Q5RJ44|uniprotkb:Q5RJ45|uniprotkb:Q7KYX2|uniprotkb:Q96CD5|uniprotkb:Q9UKB6|uniprotkb:B2R7D8 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:cenpr_human(display_long)|uniprotkb:Nuclear receptor-interacting factor 3(gene name synonym)|uniprotkb:Integrin beta-3-binding protein(gene name synonym)|uniprotkb:Beta-3-endonexin(gene name synonym)|uniprotkb:ITGB3BP(gene name)|psi-mi:ITGB3BP(display_short)|uniprotkb:NRIF3(gene name synonym)|uniprotkb:CENPR(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000142856(gene)|ensembl:ENST00000271002(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0051301"(cell division)|interpro:IPR009601(Nuclear receptor co-activator NRIF3)|mint:Q13352|reactome:R-HSA-141444|reactome:R-HSA-205043|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:NP_001334077.1|refseq:NP_001193668.1|refseq:NP_055103.3 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:7GYfMmMv0+wKjQkvxDDcTn8Qx2Y9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q13011 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-711968|ensembl:ENSP00000221418|ensembl:ENSP00000489530|uniprotkb:Q8WVX0|uniprotkb:Q96EZ9|uniprotkb:A8K745 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ech1_human(display_long)|uniprotkb:ECH1(gene name)|psi-mi:ECH1(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000104823(gene)|ensembl:ENSG00000282853(gene)|ensembl:ENST00000221418(transcript)|ensembl:ENST00000634245(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016020"(membrane)|go:"GO:0051750"("delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:Q13011|rcsb pdb:2VRE|reactome:R-HSA-9033241|refseq:NP_001389.2 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:gh0bwdUu9tkSTHWuySCaTXIQGzI9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9BRP8 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9BSM1 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q6SPF0 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-8833536|uniprotkb:Q96IM4|uniprotkb:Q6PIS7|uniprotkb:Q6P0R3 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:samd1_human(display_long)|uniprotkb:SAMD1(gene name)|psi-mi:SAMD1(display_short)|uniprotkb:Atherin(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 mint:Q6SPF0|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_612361.1|go:"GO:0005737"(cytoplasm)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:6LUI|rcsb pdb:6LUJ|rcsb pdb:6LUK|go:"GO:0003682"(chromatin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:Cav/ZfHiZJ1xCBI6jAYrzv+CmZ49606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O60684 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q16630 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_008938.2|refseq:NP_001287876.1|ensembl:ENSG00000111605(gene)|ensembl:ENST00000435070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042382"(paraspeckles)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990448"(exon-exon junction complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|reactome:R-HSA-1839117|reactome:R-HSA-5655302|dip:DIP-34501N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P55198 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-740216|uniprotkb:Q9UF49|intact:EBI-945884|intact:EBI-28966978|ensembl:ENSP00000477969|ensembl:ENSP00000479910|uniprotkb:Q59F28|uniprotkb:Q9H5F6|uniprotkb:Q96IU3 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:af17_human(display_long)|uniprotkb:MLLT6(gene name)|psi-mi:MLLT6(display_short)|uniprotkb:AF17(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 17 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSP00000477969|ensembl:ENSP00000479910|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0035812"(renal sodium excretion)|go:"GO:0036359"(renal potassium excretion)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:2001161"(negative regulation of histone H3-K79 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|ensembl:ENSG00000275023(gene)|ensembl:ENSG00000275851(gene)|ensembl:ENST00000618876(transcript)|ensembl:ENST00000621332(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0031491"(nucleosome binding)|refseq:NP_005928.2 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:VcJKH3p3r1+7OGgwYfeR5plOfz49606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P78563 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2967304|uniprotkb:C3TTQ1|ensembl:ENSP00000353920|ensembl:ENSP00000414600|ensembl:ENSP00000435381|uniprotkb:A6NFK8|uniprotkb:Q8NFD1|uniprotkb:A6NJ84|uniprotkb:Q4AE79|uniprotkb:O00691|uniprotkb:O00465|uniprotkb:O00692|uniprotkb:O00395|uniprotkb:P78555|uniprotkb:Q4AE77|uniprotkb:Q8NFA1|uniprotkb:C9JUP4|uniprotkb:G5E9B4|uniprotkb:Q6P0M9|uniprotkb:C3TTQ2 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:red1_human(display_long)|uniprotkb:ADARB1(gene name)|psi-mi:ADARB1(display_short)|uniprotkb:ADAR2(gene name synonym)|uniprotkb:DRADA2(gene name synonym)|uniprotkb:RED1(gene name synonym)|uniprotkb:RNA-editing deaminase 1(gene name synonym)|uniprotkb:RNA-editing enzyme 1(gene name synonym)|uniprotkb:dsRNA adenosine deaminase(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000197381(gene)|ensembl:ENST00000360697(transcript)|ensembl:ENST00000437626(transcript)|ensembl:ENST00000496664(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0021610"(facial nerve morphogenesis)|go:"GO:0021618"(hypoglossal nerve morphogenesis)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060384"(innervation)|go:"GO:0060415"(muscle tissue morphogenesis)|go:"GO:0061744"(motor behavior)|go:"GO:0097049"(motor neuron apoptotic process)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR044458|interpro:IPR044459|rcsb pdb:1ZY7|rcsb pdb:5ED1|rcsb pdb:5ED2|rcsb pdb:5HP2|rcsb pdb:5HP3|rcsb pdb:6D06|rcsb pdb:6VFF|rcsb pdb:7KFN|reactome:R-HSA-75102|reactome:R-HSA-77042|go:"GO:0045202"(synapse)|refseq:NP_001153702.1|refseq:NP_001103.1|refseq:NP_056648.1|refseq:NP_056649.1|refseq:XP_016883736.1|refseq:XP_016883737.1|refseq:XP_016883738.1|refseq:XP_016883739.1|refseq:XP_016883740.1|refseq:XP_016883743.1|refseq:XP_016883744.1|refseq:NP_001333616.1|refseq:NP_001333617.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:+Fg4bnHevwawu/xIZlP/I1Mcr3I9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O00422 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1044156|uniprotkb:Q2TTR4|uniprotkb:Q6IAW9|uniprotkb:Q8N606|uniprotkb:Q9UF14|ensembl:ENSP00000475925|uniprotkb:B2R494|uniprotkb:X6RAL5 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:sap18_human(display_long)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 38 protein(gene name synonym)|uniprotkb:2HOR0202(gene name synonym)|uniprotkb:SAP18(gene name)|psi-mi:SAP18(display_short)|uniprotkb:GIG38(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000150459(gene)|ensembl:ENST00000607003(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O00422|rcsb pdb:2HDE|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|refseq:NP_005861.2|dip:DIP-33590N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:eJoksFCc7vBoAjJEpnXJvc/yg+Q9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9ULL5 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2803349|uniprotkb:E9PB06|uniprotkb:Q8N4J6|intact:EBI-28976287|ensembl:ENSP00000394510 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:prr12_human(display_long)|uniprotkb:KIAA1205(gene name synonym)|uniprotkb:PRR12(gene name)|psi-mi:PRR12(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSP00000394510|refseq:NP_065770.1|ensembl:ENSG00000126464(gene)|ensembl:ENST00000418929(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043005"(neuron projection)|interpro:IPR025451 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:wWq0/S4FG/9wrPyvqU9CyvIQSA09606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P52298 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q09161 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9BXP5 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|ensembl:ENSP00000480421|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENST00000611405(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|reactome:R-HSA-6807505|reactome:R-HSA-72163|ensembl:ENSG00000087087(gene)|refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q96PV6 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|intact:EBI-28984630|ensembl:ENSP00000318374|ensembl:ENSP00000478337|ensembl:ENSP00000478975|ensembl:ENSP00000480663|uniprotkb:A0A087WTE7 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_443157.1|ensembl:ENSG00000167615(gene)|ensembl:ENSG00000274305(gene)|ensembl:ENSG00000276458(gene)|ensembl:ENSG00000276681(gene)|ensembl:ENST00000326764(transcript)|ensembl:ENST00000617180(transcript)|ensembl:ENST00000621306(transcript)|ensembl:ENST00000622672(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|mint:Q96PV6|ensembl:ENSP00000318374|ensembl:ENST00000610314|ensembl:ENSP00000484494|ensembl:ENST00000611866|ensembl:ENSP00000479293|ensembl:ENST00000616932|ensembl:ENSP00000477813|ensembl:ENSP00000480663|ensembl:ENST00000617420|ensembl:ENSP00000481040|ensembl:ENSP00000478337|ensembl:ENSP00000478975|refseq:XP_011524717.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:kwgKuV5NW0hITukndsYeyQHTdd09606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9UHI6 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9UKV3 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-396258|uniprotkb:O75158|uniprotkb:Q9UG91|uniprotkb:Q9UKV1|uniprotkb:Q9UKV2|uniprotkb:D3DS45|uniprotkb:B2RTT4|ensembl:ENSP00000262710 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:acinu_human(display_long)|uniprotkb:ACIN1(gene name)|psi-mi:ACIN1(display_short)|uniprotkb:ACINUS(gene name synonym)|uniprotkb:KIAA0670(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001158286.1|refseq:NP_001158287.1|refseq:NP_001158288.1|refseq:NP_001158289.1|refseq:NP_055792.1|refseq:XP_005267475.1|ensembl:ENSG00000100813(gene)|ensembl:ENST00000262710(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034257|interpro:IPR035979|interpro:IPR036361|mint:Q9UKV3|rcsb pdb:6G6S|reactome:R-HSA-111465|interpro:IPR032552|dip:DIP-32963N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:dzHCIefdTYTGEk+qXNwlK2Phybw9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q86U42 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q13155 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P34897 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9UKS6 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-77926|ensembl:ENSP00000298838|ensembl:ENSP00000440945|uniprotkb:A6NH84|uniprotkb:Q9H331|uniprotkb:Q9NWV9 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:pacn3_human(display_long)|uniprotkb:PACSIN3(gene name)|psi-mi:PACSIN3(display_short)|uniprotkb:SH3 domain-containing protein 6511(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028523|interpro:IPR031160|interpro:IPR036028|mint:Q9UKS6|reactome:R-HSA-8856828|ensembl:ENSG00000165912(gene)|ensembl:ENST00000298838(transcript)|ensembl:ENST00000539589(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_001171903.1|refseq:NP_001171904.1|refseq:NP_057307.2 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:kxgltMI3NBu8k0ihTG8Nce63cQE9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O14950 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P53582 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1051435|uniprotkb:B4E2E6|ensembl:ENSP00000296411 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:map11_human(display_long)|uniprotkb:Peptidase M 1(gene name synonym)|uniprotkb:METAP1(gene name)|psi-mi:METAP1(display_short)|uniprotkb:KIAA0094(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_055958.2|ensembl:ENSG00000164024(gene)|ensembl:ENST00000296411(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0031365"(N-terminal protein amino acid modification)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|go:"GO:0070527"(platelet aggregation)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|interpro:IPR031615|interpro:IPR036005|rcsb pdb:2B3H|rcsb pdb:2B3K|rcsb pdb:2B3L|rcsb pdb:2G6P|rcsb pdb:2GZ5|rcsb pdb:2NQ6|rcsb pdb:2NQ7|rcsb pdb:4FLI|rcsb pdb:4FLJ|rcsb pdb:4FLK|rcsb pdb:4FLL|rcsb pdb:4HXX|rcsb pdb:4IKR|rcsb pdb:4IKS|rcsb pdb:4IKT|rcsb pdb:4IKU|rcsb pdb:4IU6|rcsb pdb:4U1B|rcsb pdb:4U69|rcsb pdb:4U6C|rcsb pdb:4U6E|rcsb pdb:4U6J|rcsb pdb:4U6W|rcsb pdb:4U6Z|rcsb pdb:4U70|rcsb pdb:4U71|rcsb pdb:4U73|rcsb pdb:4U75|rcsb pdb:4U76|rcsb pdb:5YKP|rcsb pdb:5YR4|rcsb pdb:5YR5|rcsb pdb:5YR6|rcsb pdb:5YR7|rcsb pdb:6LZB|rcsb pdb:6LZC|reactome:R-HSA-2514859 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:rjlwnLqFUpQLlzyigVWlNAQ9XUw9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P20700 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P68400 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q5JVF3 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1051701|uniprotkb:A6NK09|uniprotkb:Q3ZCX1|uniprotkb:Q5TC57|uniprotkb:Q5TC58|uniprotkb:Q9H7K1|uniprotkb:Q9HBZ7|uniprotkb:Q9NUK6|uniprotkb:Q9NVY1|uniprotkb:Q9NW44|uniprotkb:Q9NWH3|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:pcid2_human(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short)|uniprotkb:HT004(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001120674.1|refseq:NP_001120675.1|refseq:NP_060856.2|refseq:NP_001245142.1|refseq:NP_001307584.1|refseq:NP_001307585.1|refseq:NP_001307586.1|refseq:NP_001307589.1|ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|rcsb pdb:3T5X|refseq:XP_016876153.1|dip:DIP-50497N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P19784 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O00629 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:/cng/xZ42E2juzHNOpuQTP+amx89606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P68036 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q96A72 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-746778|ensembl:ENSP00000319240 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:mgn2_human(display_long)|uniprotkb:MAGOH2(gene name synonym)|uniprotkb:MAGOHB(gene name)|psi-mi:MAGOHB(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0043025"(neuronal cell body)|refseq:NP_060518.1|refseq:NP_001306914.1|ensembl:ENSG00000111196(gene)|ensembl:ENST00000320756(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008380"(RNA splicing)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|go:"GO:0051028"(mRNA transport) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:yZXZX4T3KYVVSCTJFNbLx3qmDWU9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9Y5S9 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-447231|uniprotkb:Q6FHD1|uniprotkb:Q6IQ40|uniprotkb:Q9GZX8|uniprotkb:Q9NZI4|uniprotkb:B3KQI9|intact:EBI-28979675|ensembl:ENSP00000463058|ensembl:ENSP00000488265 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:rbm8a_human(display_long)|uniprotkb:HSPC114(orf name)|uniprotkb:MDS014(orf name)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym)|uniprotkb:RNA-binding protein Y14(gene name synonym)|uniprotkb:Binder of OVCA1-1(gene name synonym)|uniprotkb:RBM8A(gene name)|psi-mi:RBM8A(display_short)|uniprotkb:RBM8(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_005096.1|ensembl:ENST00000369307|ensembl:ENSP00000358313|ensembl:ENSP00000463058|ensembl:ENSP00000488265|dip:DIP-33070N|ensembl:ENSG00000265241(gene)|ensembl:ENST00000583313(transcript)|ensembl:ENST00000632555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9Y5S9|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb09606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P15692 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1026643|uniprotkb:O60720|uniprotkb:O75875|uniprotkb:Q074Z4|uniprotkb:Q16889|uniprotkb:Q5UB46|uniprotkb:Q6P0P5|uniprotkb:Q96KJ0|uniprotkb:Q96L82|uniprotkb:Q96NW5|uniprotkb:Q9H1W8|uniprotkb:Q9H1W9|uniprotkb:Q9UH58|uniprotkb:Q9UL23|uniprotkb:B5BU86|ensembl:ENSP00000430479|uniprotkb:H0Y2S8|uniprotkb:H0Y407|uniprotkb:H0Y414|uniprotkb:H0Y462|uniprotkb:H0Y8N2|uniprotkb:H3BLW7 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:vegfa_human(display_long)|uniprotkb:Vascular permeability factor(gene name synonym)|uniprotkb:VEGFA(gene name)|psi-mi:VEGFA(display_short)|uniprotkb:VEGF(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001020537.2|refseq:NP_001020538.2|refseq:NP_001020539.2|refseq:NP_001020540.2|refseq:NP_001020541.2|refseq:NP_001028928.1|refseq:NP_001165093.1|refseq:NP_001165094.1|refseq:NP_001165095.1|refseq:NP_001165096.1|refseq:NP_001165097.1|refseq:NP_001165098.1|refseq:NP_001165099.1|refseq:NP_001165100.1|refseq:NP_001165101.1|refseq:NP_001191313.1|refseq:NP_001191314.1|refseq:NP_003367.4|refseq:NP_001303939.1|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060754"(positive regulation of mast cell chemotaxis)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061042"(vascular wound healing)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000112715(gene)|ensembl:ENST00000523873(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007498"(mesoderm development)|go:"GO:0007595"(lactation)|go:"GO:0008083"(growth factor activity)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002575"(basophil chemotaxis)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0010749"(regulation of nitric oxide mediated signal transduction)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035148"(tube formation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036303"(lymph vessel morphogenesis)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0038091"(positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway)|go:"GO:0038190"(VEGF-activated neuropilin signaling pathway)|go:"GO:0038191"(neuropilin binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0031012"(extracellular matrix)|go:"GO:1903572"(positive regulation of protein kinase D signaling)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905278"(positive regulation of epithelial tube formation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000072("Platelet-derived growth factor (PDGF)")|interpro:IPR023581|interpro:IPR027928|interpro:IPR029034|interpro:IPR036841|mint:P15692|rcsb pdb:1BJ1|go:"GO:1903392"(negative regulation of adherens junction organization)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:0090259"(regulation of retinal ganglion cell axon guidance)|go:"GO:0097475"(motor neuron migration)|go:"GO:0097533"(cellular stress response to acid chemical)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1901727"(positive regulation of histone deacetylase activity)|go:"GO:1902336"(positive regulation of retinal ganglion cell axon guidance)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903141"(negative regulation of establishment of endothelial barrier)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|rcsb pdb:1FLT|rcsb pdb:1KAT|rcsb pdb:1KMX|rcsb pdb:1MJV|rcsb pdb:1MKG|rcsb pdb:1MKK|rcsb pdb:1QTY|rcsb pdb:1TZH|rcsb pdb:1TZI|rcsb pdb:1VGH|rcsb pdb:1VPF|rcsb pdb:1VPP|rcsb pdb:2FJG|rcsb pdb:2FJH|rcsb pdb:2QR0|rcsb pdb:2VGH|rcsb pdb:2VPF|rcsb pdb:3BDY|rcsb pdb:3P9W|rcsb pdb:3QTK|rcsb pdb:3S1B|rcsb pdb:3S1K|rcsb pdb:3V2A|rcsb pdb:4DEQ|rcsb pdb:4GLN|rcsb pdb:4GLS|rcsb pdb:4KZN|rcsb pdb:4QAF|rcsb pdb:4WPB|rcsb pdb:4ZFF|rcsb pdb:5DN2|rcsb pdb:5FV1|rcsb pdb:5FV2|rcsb pdb:5HHC|rcsb pdb:5HHD|rcsb pdb:5O4E|rcsb pdb:1CZ8|rcsb pdb:5T89|rcsb pdb:6BFT|rcsb pdb:6D3O|rcsb pdb:6T9D|rcsb pdb:6V7K|rcsb pdb:6Z13|rcsb pdb:6Z3F|rcsb pdb:6ZBR|rcsb pdb:6ZCD|rcsb pdb:6ZFL|rcsb pdb:7LL9|reactome:R-HSA-114608|reactome:R-HSA-1234158|reactome:R-HSA-194138|reactome:R-HSA-194313|reactome:R-HSA-195399|reactome:R-HSA-4420097|reactome:R-HSA-5218921|reactome:R-HSA-6785807|reactome:R-HSA-8866910|reactome:R-HSA-9679191|rcsb pdb:7LL8|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043117"(positive regulation of vascular permeability)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043183"(vascular endothelial growth factor receptor 1 binding)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0042462"(eye photoreceptor cell development)|refseq:NP_001273973.1|dip:DIP-5740N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:O5iw4Qx7W34QAg3oFkltpRxDYwA9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P35637 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q00688 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1044081|uniprotkb:Q14317|ensembl:ENSP00000216330|ensembl:ENSP00000379374|uniprotkb:B2R4Q9 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:fkbp3_human(display_long)|uniprotkb:FKBP3(gene name)|psi-mi:FKBP3(display_short)|uniprotkb:FKBP25(gene name synonym)|uniprotkb:FK506-binding protein 3(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP25(gene name synonym)|uniprotkb:Rapamycin-selective 25 kDa immunophilin(gene name synonym)|uniprotkb:25 kDa FK506-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_002004.1|ensembl:ENSG00000100442(gene)|ensembl:ENST00000216330(transcript)|ensembl:ENST00000396062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR041200|interpro:IPR043368|mint:Q00688|rcsb pdb:1PBK|rcsb pdb:2KFV|rcsb pdb:2MPH|rcsb pdb:5D75|rcsb pdb:5GPG|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:xU5FDlTZzy8veAtOaoLtQMeBsr09606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P98179 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2949699|ensembl:ENSP00000365946|ensembl:ENSP00000365950 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:rbm3_human(display_long)|uniprotkb:RBM3(gene name)|psi-mi:RBM3(display_short)|uniprotkb:RNPL(gene name synonym)|uniprotkb:RNA-binding motif protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0030425"(dendrite)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034278|interpro:IPR035979|mint:P98179|go:"GO:0006417"(regulation of translation)|ensembl:ENSG00000102317(gene)|ensembl:ENST00000376755(transcript)|ensembl:ENST00000376759(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_006734.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:+KPnDlgXy+KGVDjTilKMXb5dJGs9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9P289 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:O00505 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q96K17 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-6137496|uniprotkb:D3DQ32|uniprotkb:B3KNJ1|uniprotkb:G3V1C6|ensembl:ENSP00000360664 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:bt3l4_human(display_long)|uniprotkb:BTF3L4(gene name)|psi-mi:BTF3L4(display_short)|uniprotkb:Basic transcription factor 3-like 4(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_689478.1|refseq:NP_001230696.1|refseq:NP_001129969.1|ensembl:ENSG00000134717(gene)|ensembl:ENST00000313334(transcript)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:UL7VE0uKz9mYvpFq8E2FLKrBmOA9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q9H307 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-681904|uniprotkb:Q9UQR9|uniprotkb:O60899|uniprotkb:Q53EM7|uniprotkb:Q6P5X4|uniprotkb:Q7KYL1|uniprotkb:Q99738|uniprotkb:Q9UHZ9|uniprotkb:B4DZX8|ensembl:ENSP00000216832 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:pinin_human(display_long)|uniprotkb:140 kDa nuclear and cell adhesion-related phosphoprotein(gene name synonym)|uniprotkb:Domain-rich serine protein(gene name synonym)|uniprotkb:Melanoma metastasis clone A protein(gene name synonym)|uniprotkb:Desmosome-associated protein(gene name synonym)|uniprotkb:SR-like protein(gene name synonym)|uniprotkb:Nuclear protein SDK3(gene name synonym)|uniprotkb:PNN(gene name)|psi-mi:PNN(display_short)|uniprotkb:DRS(gene name synonym)|uniprotkb:MEMA(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_002678.2|dip:DIP-32950N|ensembl:ENSG00000100941(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR006787(Pinin/SDK)|interpro:IPR039853|mint:Q9H307|ensembl:ENST00000216832(transcript) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:1pAhD0z8tks+HkWaYWkdMmSjk3s9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q96J01 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2510823|ensembl:ENSP00000265097|uniprotkb:Q6NZ53 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:thoc3_human(display_long)|uniprotkb:THOC3(gene name)|psi-mi:THOC3(display_short)|uniprotkb:TEX1 homolog(gene name synonym)|uniprotkb:hTREX45(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000051596(gene)|ensembl:ENST00000265097(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|interpro:IPR040132|mint:Q96J01|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_115737.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:ENG6Gf3Q6WsTn5qkASarueRR+qc9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q8NI27 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1755078|intact:EBI-2802903|uniprotkb:A6NM50|uniprotkb:Q9H8I6|uniprotkb:Q5JZ12|uniprotkb:Q6IN92|ensembl:ENSP00000245838|ensembl:ENSP00000347959 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:thoc2_human(display_long)|uniprotkb:hTREX120(gene name synonym)|uniprotkb:THOC2(gene name)|psi-mi:THOC2(display_short)|uniprotkb:CXorf3(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001075019.1|ensembl:ENSG00000125676(gene)|ensembl:ENST00000245838(transcript)|ensembl:ENST00000355725(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048666"(neuron development)|go:"GO:0048699"(generation of neurons)|interpro:IPR021418|interpro:IPR021726|interpro:IPR032302|interpro:IPR040007|mint:Q8NI27|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:GJCI/aEu/upu9s/gMVJvt56PXP89606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q13769 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-5280316|uniprotkb:O60839|uniprotkb:Q9UPZ5|ensembl:ENSP00000380969|ensembl:ENSP00000380970|ensembl:ENSP00000380971|ensembl:ENSP00000420306 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:thoc5_human(display_long)|uniprotkb:THOC5(gene name)|psi-mi:THOC5(display_short)|uniprotkb:C22orf19(gene name synonym)|uniprotkb:KIAA0983(gene name synonym)|uniprotkb:Functional spliceosome-associated protein 79(gene name synonym)|uniprotkb:NF2/meningioma region protein pK1.3(gene name synonym)|uniprotkb:Placental protein 39.2(gene name synonym)|uniprotkb:hTREX90(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001002877.1|refseq:NP_001002878.1|refseq:NP_001002879.1|refseq:NP_003669.4|ensembl:ENSG00000100296(gene)|ensembl:ENST00000397871(transcript)|ensembl:ENST00000397872(transcript)|ensembl:ENST00000397873(transcript)|ensembl:ENST00000490103(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR019163|mint:Q13769|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:JoeUa2WhtV/dR2HSjUEBAHDZZtw9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q13838 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q86W42 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-2880668|ensembl:ENSP00000326531|uniprotkb:Q8NBR1|uniprotkb:B2RA85|uniprotkb:Q9BTV9 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:thoc6_human(display_long)|uniprotkb:THOC6(gene name)|psi-mi:THOC6(display_short)|uniprotkb:WDR58(gene name synonym)|uniprotkb:Functional spliceosome-associated protein 35(gene name synonym)|uniprotkb:WD repeat-containing protein 58(gene name synonym)|uniprotkb:PSEC0006(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000131652(gene)|ensembl:ENST00000326266(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR042626|mint:Q86W42|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_001135822.1|refseq:NP_077315.2|refseq:NP_001334632.1|refseq:NP_001334633.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:mmpU10uiZc1+MK8ntLeD+GCVIOM9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q96FV9 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1765605|uniprotkb:Q15219|uniprotkb:B2RBP6|uniprotkb:Q64I72|uniprotkb:Q64I73|intact:EBI-28984554|ensembl:ENSP00000261600 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:thoc1_human(display_long)|uniprotkb:hTREX84(gene name synonym)|uniprotkb:THOC1(gene name)|psi-mi:THOC1(display_short)|uniprotkb:HPR1(gene name synonym)|uniprotkb:Nuclear matrix protein p84(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_005122.2|ensembl:ENSP00000261600|ensembl:ENSG00000079134(gene)|ensembl:ENST00000261600(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048297"(negative regulation of isotype switching to IgA isotypes)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR021861|mint:Q96FV9|rcsb pdb:1WXP|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:D+lk5iFzcmd1bQRa2cx/nUyq4sI9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P38919 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-299104|ensembl:ENSP00000497641|ensembl:ENSP00000497661|uniprotkb:Q15033|uniprotkb:Q96A18|uniprotkb:Q6IBQ2 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:if4a3_human(display_long)|uniprotkb:KIAA0111(gene name synonym)|uniprotkb:EIF4A3(gene name)|psi-mi:EIF4A3(display_short)|uniprotkb:DDX48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)|uniprotkb:Eukaryotic initiation factor 4A-like NUK-34(gene name synonym)|uniprotkb:Nuclear matrix protein 265(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008306"(associative learning)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072715"(cellular response to selenite ion)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P38919|rcsb pdb:2HXY|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:7A5P|reactome:R-HSA-1169408|reactome:R-HSA-159236|reactome:R-HSA-429947|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENST00000647795(transcript)|ensembl:ENST00000649764(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|ensembl:ENSG00000141543(gene)|refseq:NP_055555.1|dip:DIP-33218N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:8e6e4HlM1GsYqqgXyJ9XgzxLzls9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:Q6I9Y2 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-716286|uniprotkb:Q6P1L3|uniprotkb:Q8WUF2|uniprotkb:Q9H5H0|ensembl:ENSP00000295899 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:thoc7_human(display_long)|uniprotkb:Functional spliceosome-associated protein 24(gene name synonym)|uniprotkb:hTREX30(gene name synonym)|uniprotkb:NIF3L1BP1(gene name synonym)|uniprotkb:Ngg1-interacting factor 3-like protein 1-binding protein 1(gene name synonym)|uniprotkb:THOC7(gene name)|psi-mi:THOC7(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001272333.1|refseq:NP_079351.2|ensembl:ENSG00000163634(gene)|ensembl:ENST00000295899(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR008501(Protein of unknown function DUF783)|mint:Q6I9Y2|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:15M7nouxNuzlKZPawajrahz0LAY9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P51148 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689|ensembl:ENSP00000377440 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_004574.2|refseq:NP_958842.1|refseq:XP_011523392.1|refseq:XP_011523393.1|refseq:NP_001238968.1|ensembl:ENSG00000108774(gene)|ensembl:ENST00000346213(transcript)|ensembl:ENST00000393860(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53F19 uniprotkb:P50395 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623276|imex:IM-26480-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:Tl+JpUwPOk4Q1lkU+mmjJMh8XBk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9UH99 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P04003 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-978348|ensembl:ENSP00000356037|uniprotkb:Q5VVQ8 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:c4bpa_human(display_long)|uniprotkb:Proline-rich protein(gene name synonym)|uniprotkb:C4BPA(gene name)|psi-mi:C4BPA(display_short)|uniprotkb:C4BP(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSG00000123838(gene)|ensembl:ENST00000367070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009609"(response to symbiotic bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045959"(negative regulation of complement activation, classical pathway)|go:"GO:0072562"(blood microparticle)|go:"GO:1903027"(regulation of opsonization)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR040514|rcsb pdb:2A55|rcsb pdb:4B0F|rcsb pdb:5HYP|rcsb pdb:5HYT|rcsb pdb:5HYU|rcsb pdb:5HZP|rcsb pdb:5I0Q|reactome:R-HSA-977606|refseq:NP_000706.1|refseq:XP_005273308.1|refseq:XP_005273309.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:S0F99wuDTalS4UCuYGWbiCgWlO09606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q8N0X7 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-2643803|uniprotkb:Q9H1T3|uniprotkb:Q9H1T2|uniprotkb:O60349|uniprotkb:Q86Y67|ensembl:ENSP00000347314|ensembl:ENSP00000406061|ensembl:ENSP00000414147|ensembl:ENSP00000473599|ensembl:ENSP00000497209 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:spart_human(display_long)|uniprotkb:SPART(gene name)|psi-mi:SPART(display_short)|uniprotkb:KIAA0610(gene name synonym)|uniprotkb:SPG20(gene name synonym)|uniprotkb:Spastic paraplegia 20 protein(gene name synonym)|uniprotkb:TAHCCP1(gene name synonym)|uniprotkb:Trans-activated by hepatitis C virus core protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001135766.1|refseq:NP_001135767.1|refseq:NP_001135768.1|refseq:NP_055902.1|refseq:XP_011533314.1|refseq:XP_005266370.1|refseq:XP_005266371.1|refseq:XP_005266372.1|ensembl:ENSG00000133104(gene)|ensembl:ENST00000355182(transcript)|ensembl:ENST00000438666(transcript)|ensembl:ENST00000451493(transcript)|ensembl:ENST00000494062(transcript)|ensembl:ENST00000650221(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009838"(abscission)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0048698"(negative regulation of collateral sprouting in absence of injury)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051301"(cell division)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060612"(adipose tissue development)|interpro:IPR007330(MIT)|interpro:IPR009686(Senescence-associated)|interpro:IPR036181|rcsb pdb:2DL1|rcsb pdb:4U7I|go:"GO:0030514"(negative regulation of BMP signaling pathway)|refseq:XP_005266374.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:Km2bYRg7JLYy7voEgYVdAHZhzE09606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:K7ELV2 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-20623426|ensembl:ENSP00000466234 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:k7elv2_human(display_long)|uniprotkb:SEH1L(gene name)|psi-mi:SEH1L(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSG00000085415(gene)|ensembl:ENST00000587761(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0015031"(protein transport)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037597 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:r1BEnabXSY5UMmviBPcVCVl5QFg9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P14735 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-2556886|uniprotkb:Q5T5N2|uniprotkb:D3DR35|ensembl:ENSP00000265986|uniprotkb:B2R721|uniprotkb:B7ZAU2 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ide_human(display_long)|uniprotkb:IDE(gene name)|psi-mi:IDE(display_short)|uniprotkb:Insulin protease(gene name synonym)|uniprotkb:Insulysin(gene name synonym)|uniprotkb:Abeta-degrading protease(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_004960.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010815"(bradykinin catabolic process)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031626"(beta-endorphin binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000119912(gene)|ensembl:ENST00000265986(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0043559"(insulin binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1901143"(insulin catabolic process)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR032632|mint:P14735|rcsb pdb:2G47|rcsb pdb:2G48|rcsb pdb:2G49|rcsb pdb:2G54|rcsb pdb:2G56|rcsb pdb:2JBU|rcsb pdb:2JG4|rcsb pdb:2WBY|rcsb pdb:2WC0|rcsb pdb:2WK3|rcsb pdb:2YPU|rcsb pdb:3CWW|rcsb pdb:3E4A|rcsb pdb:3E4Z|rcsb pdb:3E50|rcsb pdb:3H44|rcsb pdb:3N56|rcsb pdb:3N57|rcsb pdb:3OFI|rcsb pdb:3QZ2|rcsb pdb:4DTT|rcsb pdb:4DWK|rcsb pdb:4GS8|rcsb pdb:4GSC|rcsb pdb:4GSF|rcsb pdb:4IFH|rcsb pdb:4IOF|rcsb pdb:4LTE|rcsb pdb:4M1C|rcsb pdb:4NXO|rcsb pdb:4PES|rcsb pdb:4PF7|rcsb pdb:4PF9|rcsb pdb:4PFC|rcsb pdb:4QIA|rcsb pdb:4RAL|rcsb pdb:4RE9|rcsb pdb:5CJO|rcsb pdb:3HGZ|rcsb pdb:5UOE|rcsb pdb:5WOB|rcsb pdb:6B3Q|rcsb pdb:6B70|rcsb pdb:6B7Y|rcsb pdb:6BF6|rcsb pdb:6BF7|rcsb pdb:6BF8|rcsb pdb:6BF9|rcsb pdb:6BFC|rcsb pdb:6BYZ|rcsb pdb:6EDS|rcsb pdb:6MQ3|reactome:R-HSA-5689880|reactome:R-HSA-9033241|rcsb pdb:6B7Z|refseq:NP_001159418.1|dip:DIP-55771N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:dwngN3kUOExC5qapSgF01YhBNAM9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q5VV67 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-1045850|uniprotkb:Q5VV66|uniprotkb:Q6P3U5|uniprotkb:Q6P3W1|uniprotkb:Q76N31|uniprotkb:Q9BUJ3|uniprotkb:Q9BZE5|uniprotkb:Q9Y4E0|intact:EBI-28968769|ensembl:ENSP00000278070 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:pprc1_human(display_long)|uniprotkb:PGC-1-related coactivator(gene name synonym)|uniprotkb:PPRC1(gene name)|psi-mi:PPRC1(display_short)|uniprotkb:KIAA0595(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSP00000278070|refseq:NP_055877.3|ensembl:ENSG00000148840(gene)|ensembl:ENST00000278070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034597|interpro:IPR034605|interpro:IPR034834|interpro:IPR035979|reactome:R-HSA-2151201|refseq:NP_001275656.1|refseq:NP_001275657.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:CzoJyQC7ZylKapYmIL3Ik5IxhBk9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P31150 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-946999|uniprotkb:P50394|uniprotkb:Q7Z2G6|uniprotkb:Q7Z2G9|uniprotkb:Q7Z2H5|uniprotkb:Q7Z2I6|uniprotkb:Q6FG50|ensembl:ENSP00000394071 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:gdia_human(display_long)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:OPHN2(gene name synonym)|uniprotkb:RABGDIA(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 1(gene name synonym)|uniprotkb:Oligophrenin-2(gene name synonym)|uniprotkb:Protein XAP-4(gene name synonym)|uniprotkb:GDIL(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001484.1|ensembl:ENSG00000203879(gene)|ensembl:ENST00000447750(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0051592"(response to calcium ion)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P31150|reactome:R-HSA-8876198 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:bE8RgEdzf7V/T+hWdGJkM9WM0yI9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q5DJT8 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-11064777|uniprotkb:Q5JRH3|ensembl:ENSP00000474632|ensembl:ENSP00000483619 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ct452_human(display_long)|uniprotkb:CT45A2(gene name)|psi-mi:CT45A2(display_short)|uniprotkb:CT45-2(gene name synonym)|uniprotkb:Cancer/testis antigen 45-2(gene name synonym)|uniprotkb:Cancer/testis antigen 45A2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001278464.1|refseq:NP_001278469.1|refseq:NP_689795.4|refseq:XP_006724846.1|refseq:XP_006724859.1|refseq:XP_006724862.1|refseq:XP_011529543.1|refseq:XP_011529691.1|refseq:NP_001308200.1|ensembl:ENSG00000271449(gene)|ensembl:ENST00000605791(transcript)|ensembl:ENST00000612907(transcript)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR029307 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:oJ5qFXTBCXlZW4PS1HrSyrS8iaQ9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P52294 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P09603 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-2872294|ensembl:ENSP00000327513|ensembl:ENSP00000358817|uniprotkb:Q14806|uniprotkb:Q5VVF4|uniprotkb:Q14086|uniprotkb:A8K6J5|uniprotkb:Q13130|uniprotkb:Q9UQR8|uniprotkb:Q5VVF3 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:csf1_human(display_long)|uniprotkb:CSF1(gene name)|psi-mi:CSF1(display_short)|uniprotkb:Lanimostim(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSG00000184371(gene)|ensembl:ENST00000329608(transcript)|ensembl:ENST00000369802(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002158"(osteoclast proliferation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0005125"(cytokine activity)|go:"GO:0005157"(macrophage colony-stimulating factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010743"(regulation of macrophage derived foam cell differentiation)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032946"(positive regulation of mononuclear cell proliferation)|go:"GO:0038145"(macrophage colony-stimulating factor signaling pathway)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042117"(monocyte activation)|go:"GO:0042488"(positive regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060611"(mammary gland fat development)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902228"(positive regulation of macrophage colony-stimulating factor signaling pathway)|go:"GO:1904141"(positive regulation of microglial cell migration)|go:"GO:1905523"(positive regulation of macrophage migration)|interpro:IPR008001(Macrophage colony stimulating factor-1)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HMC|rcsb pdb:3UEZ|rcsb pdb:3UF2|rcsb pdb:4ADF|rcsb pdb:4FA8|rcsb pdb:4WRL|rcsb pdb:4WRM|rcsb pdb:5LXF|reactome:R-HSA-381426|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-8957275|go:"GO:1990682"(CSF1-CSF1R complex)|refseq:NP_000748.3|refseq:NP_757349.1|refseq:NP_757351.1|refseq:NP_757350.1|dip:DIP-41860N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:YSg7hoJM9d3lvDoswhhVkvt0D8I9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P53007 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_005975.1|ensembl:ENSG00000100075(gene)|ensembl:ENST00000215882(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006843"(mitochondrial citrate transmembrane transport)|go:"GO:0015137"(citrate transmembrane transporter activity)|go:"GO:0015142"(tricarboxylic acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071913"(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:P53007|reactome:R-HSA-70263|reactome:R-HSA-75105 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9NWV8 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-745725|uniprotkb:Q6FIA0|uniprotkb:Q9P018|uniprotkb:A8MQT0|uniprotkb:B4DRY9|uniprotkb:B4DVR1|ensembl:ENSP00000352408|ensembl:ENSP00000470920|ensembl:ENSP00000471605 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:baba1_human(display_long)|uniprotkb:BABAM1(gene name)|psi-mi:BABAM1(display_short)|uniprotkb:HSPC142(orf name)|uniprotkb:C19orf62(gene name synonym)|uniprotkb:NBA1(gene name synonym)|uniprotkb:Mediator of RAP80 interactions and targeting subunit of 40 kDa(gene name synonym)|uniprotkb:New component of the BRCA1-A complex(gene name synonym)|uniprotkb:MERIT40(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001028721.1|refseq:NP_054892.2|ensembl:ENSG00000105393(gene)|ensembl:ENST00000359435(transcript)|ensembl:ENST00000598188(transcript)|ensembl:ENST00000601043(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051301"(cell division)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|interpro:IPR026126|interpro:IPR036465|mint:Q9NWV8|rcsb pdb:6H3C|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:NP_001275685.1|refseq:NP_001275686.1 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:o71OvjzuL/7w4247ap7fm6i3pXU9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q8N5P1 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-5280267|uniprotkb:Q9BZ75|ensembl:ENSP00000272570|ensembl:ENSP00000386488 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:zc3h8_human(display_long)|uniprotkb:ZC3H8(gene name)|psi-mi:ZC3H8(display_short)|uniprotkb:ZC3HDC8(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_115883.2|go:"GO:0035363"(histone locus body)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|mint:Q8N5P1|reactome:R-HSA-6807505|ensembl:ENSG00000144161(gene)|ensembl:ENST00000272570(transcript)|ensembl:ENST00000409573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0033085"(negative regulation of T cell differentiation in thymus)|go:"GO:0035327" - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:ltW8I583M/LV8XKPzLRvojXc+AA9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9ULL5 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-2803349|uniprotkb:E9PB06|uniprotkb:Q8N4J6|intact:EBI-28976287|ensembl:ENSP00000394510 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:prr12_human(display_long)|uniprotkb:KIAA1205(gene name synonym)|uniprotkb:PRR12(gene name)|psi-mi:PRR12(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSP00000394510|refseq:NP_065770.1|ensembl:ENSG00000126464(gene)|ensembl:ENST00000418929(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043005"(neuron projection)|interpro:IPR025451 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:wWq0/S4FG/9wrPyvqU9CyvIQSA09606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:O94762 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-395321|ensembl:ENSP00000317636|uniprotkb:Q9P1W7|uniprotkb:Q9UNC8|uniprotkb:Q9H0B1|uniprotkb:Q6P4G0 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:recq5_human(display_long)|uniprotkb:RECQ5(gene name synonym)|uniprotkb:RECQL5(gene name)|psi-mi:RECQL5(display_short)|uniprotkb:RecQ protein-like 5(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 5(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSG00000108469(gene)|ensembl:ENST00000317905(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0051301"(cell division)|go:"GO:0051304"(chromosome separation)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010716(RecQ helicase-like 5)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032284|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_001003715.1|refseq:NP_001003716.1|refseq:NP_004250.4|mint:O94762|rcsb pdb:4BK0|rcsb pdb:5LB3|rcsb pdb:5LB5|rcsb pdb:5LB8|rcsb pdb:5LBA|refseq:XP_016880832.1|refseq:XP_016880833.1|dip:DIP-32964N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:lOMr1rIrRi78aQO2pQod/1V3Ku49606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P39880 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-719064|uniprotkb:Q75LE5|uniprotkb:Q75MT2|uniprotkb:Q75MT3|uniprotkb:Q86UJ7|uniprotkb:Q6NYH4|uniprotkb:Q9UEV5|uniprotkb:B3KV79|uniprotkb:J3KQV9|intact:EBI-28989061|ensembl:ENSP00000292535|ensembl:ENSP00000450125 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:cux1_human(display_long)|uniprotkb:CUTL1(gene name synonym)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:CUX1(gene name)|psi-mi:CUX1(display_short)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:CDP/Cux p200(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001189472.1|refseq:NP_853530.2|refseq:NP_001189474.1|ensembl:ENSP00000292535|ensembl:ENST00000360264|ensembl:ENSP00000353401|ensembl:ENST00000425244|ensembl:ENSP00000409745|ensembl:ENSP00000450125|ensembl:ENST00000549414|ensembl:ENSP00000446630|ensembl:ENST00000550008|ensembl:ENSP00000447373|ensembl:ENST00000556210|ensembl:ENSP00000451558|refseq:NP_001189473.1|refseq:NP_852477.1|ensembl:ENSG00000257923(gene)|ensembl:ENST00000292535(transcript)|ensembl:ENST00000546411(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR017970|mint:P39880|reactome:R-HSA-1839117|reactome:R-HSA-5655302|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:nzlzLWJ1xI4b6kEPnLVBKwbtwLs9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q8IXH7 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9H3P2 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-5461341|uniprotkb:A2A2T1|uniprotkb:O95392|ensembl:ENSP00000372335 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:nelfa_human(display_long)|uniprotkb:NELFA(gene name)|psi-mi:NELFA(display_short)|uniprotkb:WHSC2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 2 protein(gene name synonym)|uniprotkb:P/OKcl.15(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_005654.3|dip:DIP-48478N|ensembl:ENSP00000372335|reactome:R-HSA-75955|ensembl:ENSG00000185049(gene)|ensembl:ENST00000382882(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR037517|mint:Q9H3P2|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|go:"GO:0051571"(positive regulation of histone H3-K4 methylation) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:5p43n+2CBfrTYOtRcnBf13uqM0o9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q6NZY4 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-1263058|uniprotkb:Q7L2P6|uniprotkb:Q8N2K5|uniprotkb:Q96SK7|uniprotkb:Q9NSS2|uniprotkb:Q9NSS3|ensembl:ENSP00000488055|ensembl:ENSP00000500728 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:zchc8_human(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_060082.2|ensembl:ENSG00000033030(gene)|ensembl:ENST00000633063(transcript)|ensembl:ENST00000672018(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034470"(ncRNA processing)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR006568(PSP, proline-rich)|mint:Q6NZY4|rcsb pdb:5LXR|rcsb pdb:5LXY|rcsb pdb:6C90 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:dtjoaLAUgEGavPmqaJLPnLPHLP49606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q8WX92 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-347721|uniprotkb:Q96EW5|uniprotkb:Q9H9R4|uniprotkb:Q9ULN8|uniprotkb:Q9Y3W0|uniprotkb:A2BFA3|uniprotkb:A0A0X1KG71 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:nelfb_human(display_long)|uniprotkb:NELFB(gene name)|psi-mi:NELFB(display_short)|uniprotkb:COBRA1(gene name synonym)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:KIAA1182(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_056271.3|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-9603505|reactome:R-HSA-167290|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR010405(Cofactor of BRCA1)|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|mint:Q8WX92|dip:DIP-32670N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:riNpwaKKh9L9WBarWlYQrmWgrXY9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9Y580 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-746903|uniprotkb:Q9NUT4|uniprotkb:B2R6K8|ensembl:ENSP00000439918 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:rbm7_human(display_long)|uniprotkb:RNA-binding motif protein 7(gene name synonym)|uniprotkb:RBM7(gene name)|psi-mi:RBM7(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001272974.1|refseq:NP_001272975.1|refseq:NP_001272976.1|refseq:NP_001272977.1|refseq:NP_057174.1|ensembl:ENSG00000076053(gene)|ensembl:ENST00000540163(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034500|interpro:IPR035979|mint:Q9Y580|rcsb pdb:2M8H|rcsb pdb:5IQQ|rcsb pdb:5LXR|rcsb pdb:5LXY|dip:DIP-48833N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:d39RjBQTHAVQlOsmrxMX0NCR8CU9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q86VM9 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-1045965|uniprotkb:Q96DG4|uniprotkb:Q96MP7|ensembl:ENSP00000301011 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:zch18_human(display_long)|uniprotkb:NHN1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym)|uniprotkb:ZC3H18(gene name)|psi-mi:ZC3H18(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001281269.1|ensembl:ENST00000301011(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0050779"(RNA destabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|mint:Q86VM9|ensembl:ENSG00000158545(gene)|ensembl:ENSP00000301011|refseq:NP_653205.3 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:H9lST8OLyCpyi5AWYqFYskL0ezI9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9H814 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-5667190|uniprotkb:Q9H8W1|ensembl:ENSP00000297540 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:phax_human(display_long)|uniprotkb:RNA U small nuclear RNA export adapter protein(gene name synonym)|uniprotkb:RNUXA(gene name synonym)|uniprotkb:PHAX(gene name)|psi-mi:PHAX(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_115553.2|rcsb pdb:2XC7|reactome:R-HSA-191859|reactome:R-HSA-6807505|ensembl:ENSG00000164902(gene)|ensembl:ENST00000297540(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0015031"(protein transport)|go:"GO:0015643"(toxic substance binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043489"(RNA stabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019385|interpro:IPR038092|interpro:IPR039047|mint:Q9H814 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:5cyoxIMxtl/gBViCRP3lTsoH/RU9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P18615 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q09161 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9BXP5 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|ensembl:ENSP00000480421|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENST00000611405(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|reactome:R-HSA-6807505|reactome:R-HSA-72163|ensembl:ENSG00000087087(gene)|refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9UHI6 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process) - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q8NC51 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:O75822 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-366647|uniprotkb:Q9BUD2|uniprotkb:Q9H8Q2|uniprotkb:Q9UI65|ensembl:ENSP00000261868|uniprotkb:B4DUI3|uniprotkb:F5H425 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:eif3j_human(display_long)|uniprotkb:EIF3J(gene name)|psi-mi:EIF3J(display_short)|uniprotkb:PRO0391(orf name)|uniprotkb:EIF3S1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 1(gene name synonym)|uniprotkb:eIF-3-alpha(gene name synonym)|uniprotkb:eIF3 p35(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001271264.1|refseq:NP_001271265.1|refseq:NP_003749.2|ensembl:ENSG00000104131(gene)|ensembl:ENST00000261868(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|mint:O75822|rcsb pdb:2KRB|rcsb pdb:3BPJ|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31117N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:dJ+uqlLn3RH30Rw3COnJ+/nkk+I9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9P289 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:O00505 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P51148 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689|ensembl:ENSP00000377440 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_004574.2|refseq:NP_958842.1|refseq:XP_011523392.1|refseq:XP_011523393.1|refseq:NP_001238968.1|ensembl:ENSG00000108774(gene)|ensembl:ENST00000346213(transcript)|ensembl:ENST00000393860(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P50395 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P61927 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-2105843|uniprotkb:P02403|uniprotkb:Q6IBB4|uniprotkb:Q99883|uniprotkb:B2R4H2|ensembl:ENSP00000274242 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:rl37_human(display_long)|uniprotkb:Large ribosomal subunit protein eL37(gene name synonym)|uniprotkb:RPL37(gene name)|psi-mi:RPL37(display_short)|uniprotkb:G1.16(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623424|imex:IM-26480-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_000988.1|ensembl:ENSG00000145592(gene)|ensembl:ENST00000274242(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001569(Ribosomal protein L37e)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR018267|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Fig. 4a, Data S4, Fig S7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2019/02/20 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:0WNZ8lgxYeW91kmXUr2VQG1ULZw9606 rigid:XQxCxfs8xWYApWjuvGpSJGH1Us4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:O00505 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623690|imex:IM-26480-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:JRZVbziywuid7VZn43WPeX/HHgk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52298 uniprotkb:Q13769 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-5280316|uniprotkb:O60839|uniprotkb:Q9UPZ5|ensembl:ENSP00000380969|ensembl:ENSP00000380970|ensembl:ENSP00000380971|ensembl:ENSP00000420306 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:thoc5_human(display_long)|uniprotkb:THOC5(gene name)|psi-mi:THOC5(display_short)|uniprotkb:C22orf19(gene name synonym)|uniprotkb:KIAA0983(gene name synonym)|uniprotkb:Functional spliceosome-associated protein 79(gene name synonym)|uniprotkb:NF2/meningioma region protein pK1.3(gene name synonym)|uniprotkb:Placental protein 39.2(gene name synonym)|uniprotkb:hTREX90(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623690|imex:IM-26480-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001002877.1|refseq:NP_001002878.1|refseq:NP_001002879.1|refseq:NP_003669.4|ensembl:ENSG00000100296(gene)|ensembl:ENST00000397871(transcript)|ensembl:ENST00000397872(transcript)|ensembl:ENST00000397873(transcript)|ensembl:ENST00000490103(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR019163|mint:Q13769|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:JoeUa2WhtV/dR2HSjUEBAHDZZtw9606 rigid:JRZVbziywuid7VZn43WPeX/HHgk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52298 uniprotkb:Q9H814 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-5667190|uniprotkb:Q9H8W1|ensembl:ENSP00000297540 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:phax_human(display_long)|uniprotkb:RNA U small nuclear RNA export adapter protein(gene name synonym)|uniprotkb:RNUXA(gene name synonym)|uniprotkb:PHAX(gene name)|psi-mi:PHAX(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623690|imex:IM-26480-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_115553.2|rcsb pdb:2XC7|reactome:R-HSA-191859|reactome:R-HSA-6807505|ensembl:ENSG00000164902(gene)|ensembl:ENST00000297540(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0015031"(protein transport)|go:"GO:0015643"(toxic substance binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043489"(RNA stabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019385|interpro:IPR038092|interpro:IPR039047|mint:Q9H814 - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:5cyoxIMxtl/gBViCRP3lTsoH/RU9606 rigid:JRZVbziywuid7VZn43WPeX/HHgk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52298 uniprotkb:Q09161 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623690|imex:IM-26480-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 rigid:JRZVbziywuid7VZn43WPeX/HHgk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52298 uniprotkb:Q9BXP5 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|ensembl:ENSP00000480421|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623690|imex:IM-26480-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENST00000611405(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|reactome:R-HSA-6807505|reactome:R-HSA-72163|ensembl:ENSG00000087087(gene)|refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4 - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606 rigid:JRZVbziywuid7VZn43WPeX/HHgk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52298 uniprotkb:P38919 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-299104|ensembl:ENSP00000497641|ensembl:ENSP00000497661|uniprotkb:Q15033|uniprotkb:Q96A18|uniprotkb:Q6IBQ2 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:if4a3_human(display_long)|uniprotkb:KIAA0111(gene name synonym)|uniprotkb:EIF4A3(gene name)|psi-mi:EIF4A3(display_short)|uniprotkb:DDX48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)|uniprotkb:Eukaryotic initiation factor 4A-like NUK-34(gene name synonym)|uniprotkb:Nuclear matrix protein 265(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623690|imex:IM-26480-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008306"(associative learning)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072715"(cellular response to selenite ion)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P38919|rcsb pdb:2HXY|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:7A5P|reactome:R-HSA-1169408|reactome:R-HSA-159236|reactome:R-HSA-429947|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENST00000647795(transcript)|ensembl:ENST00000649764(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|ensembl:ENSG00000141543(gene)|refseq:NP_055555.1|dip:DIP-33218N - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:8e6e4HlM1GsYqqgXyJ9XgzxLzls9606 rigid:JRZVbziywuid7VZn43WPeX/HHgk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53F19 uniprotkb:O00505 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623729|imex:IM-26480-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:xwVoZ+8Aae8/phi366au1ViCcNg false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53F19 uniprotkb:Q13769 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-5280316|uniprotkb:O60839|uniprotkb:Q9UPZ5|ensembl:ENSP00000380969|ensembl:ENSP00000380970|ensembl:ENSP00000380971|ensembl:ENSP00000420306 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:thoc5_human(display_long)|uniprotkb:THOC5(gene name)|psi-mi:THOC5(display_short)|uniprotkb:C22orf19(gene name synonym)|uniprotkb:KIAA0983(gene name synonym)|uniprotkb:Functional spliceosome-associated protein 79(gene name synonym)|uniprotkb:NF2/meningioma region protein pK1.3(gene name synonym)|uniprotkb:Placental protein 39.2(gene name synonym)|uniprotkb:hTREX90(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623729|imex:IM-26480-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_001002877.1|refseq:NP_001002878.1|refseq:NP_001002879.1|refseq:NP_003669.4|ensembl:ENSG00000100296(gene)|ensembl:ENST00000397871(transcript)|ensembl:ENST00000397872(transcript)|ensembl:ENST00000397873(transcript)|ensembl:ENST00000490103(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR019163|mint:Q13769|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:JoeUa2WhtV/dR2HSjUEBAHDZZtw9606 rigid:xwVoZ+8Aae8/phi366au1ViCcNg false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53F19 uniprotkb:Q9H814 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-5667190|uniprotkb:Q9H8W1|ensembl:ENSP00000297540 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:phax_human(display_long)|uniprotkb:RNA U small nuclear RNA export adapter protein(gene name synonym)|uniprotkb:RNUXA(gene name synonym)|uniprotkb:PHAX(gene name)|psi-mi:PHAX(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623729|imex:IM-26480-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 refseq:NP_115553.2|rcsb pdb:2XC7|reactome:R-HSA-191859|reactome:R-HSA-6807505|ensembl:ENSG00000164902(gene)|ensembl:ENST00000297540(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0015031"(protein transport)|go:"GO:0015643"(toxic substance binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043489"(RNA stabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019385|interpro:IPR038092|interpro:IPR039047|mint:Q9H814 - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:5cyoxIMxtl/gBViCRP3lTsoH/RU9606 rigid:xwVoZ+8Aae8/phi366au1ViCcNg false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53F19 uniprotkb:P38919 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-299104|ensembl:ENSP00000497641|ensembl:ENSP00000497661|uniprotkb:Q15033|uniprotkb:Q96A18|uniprotkb:Q6IBQ2 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:if4a3_human(display_long)|uniprotkb:KIAA0111(gene name synonym)|uniprotkb:EIF4A3(gene name)|psi-mi:EIF4A3(display_short)|uniprotkb:DDX48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)|uniprotkb:Eukaryotic initiation factor 4A-like NUK-34(gene name synonym)|uniprotkb:Nuclear matrix protein 265(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623729|imex:IM-26480-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008306"(associative learning)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072715"(cellular response to selenite ion)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P38919|rcsb pdb:2HXY|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:7A5P|reactome:R-HSA-1169408|reactome:R-HSA-159236|reactome:R-HSA-429947|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENST00000647795(transcript)|ensembl:ENST00000649764(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|ensembl:ENSG00000141543(gene)|refseq:NP_055555.1|dip:DIP-33218N - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:8e6e4HlM1GsYqqgXyJ9XgzxLzls9606 rigid:xwVoZ+8Aae8/phi366au1ViCcNg false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53F19 uniprotkb:Q09161 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623729|imex:IM-26480-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 rigid:xwVoZ+8Aae8/phi366au1ViCcNg false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53F19 uniprotkb:Q9BXP5 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|ensembl:ENSP00000480421|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623729|imex:IM-26480-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 ensembl:ENST00000611405(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|reactome:R-HSA-6807505|reactome:R-HSA-72163|ensembl:ENSG00000087087(gene)|refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4 - - - figure legend:Fig. 4c|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606 rigid:xwVoZ+8Aae8/phi366au1ViCcNg false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q09161 uniprotkb:Q53F19 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623751|imex:IM-26480-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig.4 D|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2018/07/17 2018/07/18 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 rigid:xpN5OMGOGHZSXdT1PF0GDp7vrjE false tag:?-? his tag:n-n|maltose binding protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53F19 intact:EBI-13949587 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 ensembl:ENST00000621592 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:myc_mrna_transcript001_human(display_short)|psi-mi:EBI-13949587(display_long) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20623784|imex:IM-26480-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 pubmed:19029303(see-also) - - comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs." figure legend:Fig. 5c|comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - - false green fluorescent protein tag:?-? - - - psi-mi:"MI:1196"(quantitative reverse transcription pcr) psi-mi:"MI:1196"(quantitative reverse transcription pcr) uniprotkb:P52298 intact:EBI-13949587 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 ensembl:ENST00000621592 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:myc_mrna_transcript001_human(display_short)|psi-mi:EBI-13949587(display_long) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20625221|imex:IM-26480-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N pubmed:19029303(see-also) - - comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs." figure legend:Fig. 5c|comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 - - false green fluorescent protein tag:?-? - - - psi-mi:"MI:1196"(quantitative reverse transcription pcr) psi-mi:"MI:1196"(quantitative reverse transcription pcr) uniprotkb:Q53F19 intact:EBI-20626648 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 ensembl:ENST00000395123 psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:slc43a3_mrna_transcript202_human(display_short)|psi-mi:EBI-20626648(display_long) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626624|imex:IM-26480-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs." figure legend:Fig. 5c|comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - - false green fluorescent protein tag:?-? - - - psi-mi:"MI:1196"(quantitative reverse transcription pcr) psi-mi:"MI:1196"(quantitative reverse transcription pcr) uniprotkb:P52298 intact:EBI-20626648 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 ensembl:ENST00000395123 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:slc43a3_mrna_transcript202_human(display_short)|psi-mi:EBI-20626648(display_long) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626657|imex:IM-26480-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N - - - comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs." figure legend:Fig. 5c|comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 - - false green fluorescent protein tag:?-? - - - psi-mi:"MI:1196"(quantitative reverse transcription pcr) psi-mi:"MI:1196"(quantitative reverse transcription pcr) uniprotkb:P52298 intact:EBI-20626679 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 ensembl:ENST00000383925 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:rnu1-1_snrna_transcript201_human(display_short)|psi-mi:EBI-20626679(display_long) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626708|imex:IM-26480-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0607"(small nuclear rna) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N - - - comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs." figure legend:Fig. 5c|comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 - - false green fluorescent protein tag:?-? - - - psi-mi:"MI:1196"(quantitative reverse transcription pcr) psi-mi:"MI:1196"(quantitative reverse transcription pcr) uniprotkb:P52298 intact:EBI-20626717 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 ensembl:ENST00000363925 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:rnu4-1_snrna_transcript201_human(display_short)|psi-mi:EBI-20626717(display_long) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626732|imex:IM-26480-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0607"(small nuclear rna) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N - - - comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs." figure legend:Fig. 5c|comment:"We validated the differences in binding to mRNA and snRNA using qRT–PCR (Fig. 5c). NCBP2 bound mRNAs (MYC, SLC43A3) and snRNAs (U1, U4), whereas NCBP3 selectively bound mRNAs (MYC, SLC43A3) but did not enrich for snRNAs."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2018/07/17 2018/07/18 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 - - false green fluorescent protein tag:?-? - - - psi-mi:"MI:1196"(quantitative reverse transcription pcr) psi-mi:"MI:1196"(quantitative reverse transcription pcr) chebi:"CHEBI:50210" uniprotkb:Q53F19 intact:EBI-1788056 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 psi-mi:7-methyl-gtp(display_short)|psi-mi:"CHEBI:50210"(display_long) psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-20626827|imex:IM-26480-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig. 3F|comment:"A highly purified N-terminal fragment (position 1–282 amino acids) consisting of the core RRM was sufficient for selective binding (Fig. 3f)."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - false - mutation disrupting interaction strength:155-158|sufficient binding region:1-282|maltose binding protein tag:n-n|his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) intact:EBI-20623174 uniprotkb:Q9BXP5 - intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|ensembl:ENSP00000480421|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENST00000611405(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|reactome:R-HSA-6807505|reactome:R-HSA-72163|ensembl:ENSG00000087087(gene)|refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:B1ANR0 - intact:EBI-9977484|ensembl:ENSP00000361953 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:b1anr0_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:hCG_2031827(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSG00000090621(gene)|ensembl:ENST00000372862(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:lStIyupVoR9Mly5sLWTobmGAZUk9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:P11940 - intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:P18615 - intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q8IXH7 - intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q8WX92 - intact:EBI-347721|uniprotkb:Q96EW5|uniprotkb:Q9H9R4|uniprotkb:Q9ULN8|uniprotkb:Q9Y3W0|uniprotkb:A2BFA3|uniprotkb:A0A0X1KG71 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:nelfb_human(display_long)|uniprotkb:NELFB(gene name)|psi-mi:NELFB(display_short)|uniprotkb:COBRA1(gene name synonym)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:KIAA1182(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_056271.3|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-9603505|reactome:R-HSA-167290|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR010405(Cofactor of BRCA1)|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|mint:Q8WX92|dip:DIP-32670N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:riNpwaKKh9L9WBarWlYQrmWgrXY9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:P52298 - intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q09161 - intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:O00629 - intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:/cng/xZ42E2juzHNOpuQTP+amx89606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:O00505 - intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:P52292 - intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:O14879 - intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876|ensembl:ENSP00000360883|ensembl:ENSP00000505987 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_001026853.1|refseq:NP_001540.2|ensembl:ENSG00000119917(gene)|ensembl:ENST00000371811(transcript)|ensembl:ENST00000371818(transcript)|ensembl:ENST00000679781(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|dip:DIP-37890N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:P09913 - intact:EBI-3507167|uniprotkb:Q5T767|ensembl:ENSP00000360891|ensembl:ENSP00000490935|ensembl:ENSP00000505033|ensembl:ENSP00000506255 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ifit2_human(display_long)|uniprotkb:IFIT2(gene name)|psi-mi:IFIT2(display_short)|uniprotkb:G10P2(gene name synonym)|uniprotkb:IFI54(gene name synonym)|uniprotkb:ISG-54 K(gene name synonym)|uniprotkb:Interferon-induced 54 kDa protein(gene name synonym)|uniprotkb:CIG-42(gene name synonym)|uniprotkb:ISG54(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_001538.4|ensembl:ENSG00000119922(gene)|ensembl:ENST00000371826(transcript)|ensembl:ENST00000638108(transcript)|ensembl:ENST00000680809(transcript)|ensembl:ENST00000680954(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009615"(response to virus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024124|rcsb pdb:4G1T|reactome:R-HSA-909733|dip:DIP-48848N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:uF6j55sUpUNfNPuLW2cq2vw9XHI9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:P09914 - intact:EBI-745117|uniprotkb:Q96QM5|intact:EBI-11024988|uniprotkb:B3KS50|uniprotkb:D3DR31|ensembl:ENSP00000360869|uniprotkb:Q5T7J1 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ifit1_human(display_long)|uniprotkb:Interferon-induced 56 kDa protein(gene name synonym)|uniprotkb:IFIT1(gene name)|psi-mi:IFIT1(display_short)|uniprotkb:G10P1(gene name synonym)|uniprotkb:IFI56(gene name synonym)|uniprotkb:IFNAI1(gene name synonym)|uniprotkb:ISG56(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_001539.3|refseq:NP_001257857.1|refseq:NP_001257858.1|refseq:NP_001257859.1|ensembl:ENSG00000185745(gene)|ensembl:ENST00000371804(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0019060"(intracellular transport of viral protein in host cell)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043657"(host cell)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0071357"(cellular response to type I interferon)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024121|mint:P09914|rcsb pdb:4HOU|rcsb pdb:5UDI|rcsb pdb:5UDJ|rcsb pdb:5UDK|rcsb pdb:5UDL|rcsb pdb:5W5H|rcsb pdb:5W5I|rcsb pdb:6C6K|reactome:R-HSA-1169408|reactome:R-HSA-909733|dip:DIP-37898N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:ANeil+D2pneKAoDFS4Vy97BHu8A9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q8TEQ6 - intact:EBI-443630|ensembl:ENSP00000285873|uniprotkb:Q14CV0|uniprotkb:Q8WWV4|uniprotkb:Q969W4|uniprotkb:Q9H9K3|uniprotkb:Q9UFI5 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:gemi5_human(display_long)|uniprotkb:GEMIN5(gene name)|psi-mi:GEMIN5(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSG00000082516(gene)|ensembl:ENST00000285873(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0032797"(SMN complex)|go:"GO:0034718"(SMN-Gemin2 complex)|interpro:IPR036322|mint:Q8TEQ6|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5GXH|rcsb pdb:5GXI|rcsb pdb:5H1J|rcsb pdb:5H1K|go:"GO:0043022"(ribosome binding)|rcsb pdb:5H1L|rcsb pdb:5H1M|rcsb pdb:5H3S|rcsb pdb:5H3T|rcsb pdb:5H3U|rcsb pdb:5TEE|rcsb pdb:5TEF|rcsb pdb:5THA|rcsb pdb:6RNQ|rcsb pdb:6RNS|reactome:R-HSA-191859|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|refseq:NP_056280.2|refseq:NP_001239085.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:9D6k6KGv+klNdYzgQClnthCYJuo9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q8N1G2 - intact:EBI-2691086|uniprotkb:Q96FJ9|uniprotkb:Q14670|uniprotkb:A8K949|ensembl:ENSP00000362550 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:cmtr1_human(display_long)|uniprotkb:CMTR1(gene name)|psi-mi:CMTR1(display_short)|uniprotkb:Cap methyltransferase 1(gene name synonym)|uniprotkb:Cap1 2'O-ribose methyltransferase 1(gene name synonym)|uniprotkb:FTSJD2(gene name synonym)|uniprotkb:FtsJ methyltransferase domain-containing protein 2(gene name synonym)|uniprotkb:Interferon-stimulated gene 95 kDa protein(gene name synonym)|uniprotkb:KIAA0082(gene name synonym)|uniprotkb:MTR1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_055865.1|ensembl:ENSG00000137200(gene)|ensembl:ENST00000373451(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0080009"(mRNA methylation)|go:"GO:0097309"(cap1 mRNA methylation)|interpro:IPR000467(D111/G-patch)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR025816|interpro:IPR029063|interpro:IPR030376|mint:Q8N1G2|rcsb pdb:4N48|rcsb pdb:4N49|rcsb pdb:4N4A - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:mMoDk5J/tBCaxISq1Oju9BY0RVA9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q8IYT2 - intact:EBI-20626944|ensembl:ENSP00000337512|ensembl:ENSP00000411148|uniprotkb:B2RCD5|uniprotkb:D3DWS1|uniprotkb:Q8NE77|uniprotkb:Q8NFR5|uniprotkb:Q9H8Z4|uniprotkb:Q9NUS3|uniprotkb:Q9NXF5 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:cmtr2_human(display_long)|uniprotkb:Cap methyltransferase 2(gene name synonym)|uniprotkb:Cap2 2'O-ribose methyltransferase 2(gene name synonym)|uniprotkb:FtsJ methyltransferase domain-containing protein 1(gene name synonym)|uniprotkb:Protein adrift homolog(gene name synonym)|uniprotkb:CMTR2(gene name)|psi-mi:CMTR2(display_short)|uniprotkb:AFT(gene name synonym)|uniprotkb:FTSJD1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSG00000180917(gene)|ensembl:ENST00000338099(transcript)|ensembl:ENST00000434935(transcript)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0097309"(cap1 mRNA methylation)|go:"GO:0097310"(cap2 mRNA methylation)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR025807|interpro:IPR029063|refseq:NP_001093112.1|refseq:NP_001311303.1|refseq:NP_001311306.1|refseq:NP_001311307.1|refseq:NP_001311308.1|refseq:NP_060818.4|refseq:XP_011521530.1|refseq:XP_011521531.1|refseq:XP_016878933.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:X588PDTbibwjTLXcJBITsi8zTTY9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q04637 - intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q9NRA8 - intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:4A9mF81S/ePAraruTNYgovUdkT49606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q53F19 - intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:P06730 - intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:O43143 - intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20626924|imex:IM-26480-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:Proteins identified by LC-MS/MS from lysates of THP-1 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q9Z1Z2 - intact:EBI-8320895|uniprotkb:Q8BP89|intact:MINT-1870065|uniprotkb:Q8C6F6|ensembl:ENSMUSP00000068267 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:strap_mouse(display_long)|uniprotkb:Strap(gene name)|psi-mi:Strap(display_short)|uniprotkb:Unrip(gene name synonym)|uniprotkb:UNR-interacting protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_035629.2|ensembl:ENSMUSG00000030224(gene)|ensembl:ENSMUST00000064910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0022618"(ribonucleoprotein complex assembly)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:Q9Z1Z2|reactome:R-MMU-2173788 - - function:The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex|comment:mint figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:9MyPF8yI+ysf0lmDMYE+FNicL9g10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:P62315 - intact:EBI-7229109|uniprotkb:Q3UYM0|uniprotkb:P13641|intact:MINT-124808|ensembl:ENSMUSP00000002551 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:smd1_mouse(display_long)|uniprotkb:Snrpd1(gene name)|psi-mi:Snrpd1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_033252.1|ensembl:ENSMUSG00000002477(gene)|ensembl:ENSMUST00000002551(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034102|mint:P62315|reactome:R-MMU-191859|reactome:R-MMU-72163|reactome:R-MMU-72165 - - function:May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA|comment:mint figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:bfXwsV+IOjDPCoOJOoMQgECyiII10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q9CQ49 - intact:EBI-8586642|ensembl:ENSMUSP00000023460|uniprotkb:Q3UI86|intact:MINT-4613350|uniprotkb:Q0VF93 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ncbp2_mouse(display_long)|uniprotkb:Ncbp2(gene name)|psi-mi:Ncbp2(display_short)|uniprotkb:Cbp20(gene name synonym)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR027157|interpro:IPR034148|interpro:IPR035979|reactome:R-MMU-111367|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-674695|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72187|reactome:R-MMU-72203|reactome:R-MMU-73856|reactome:R-MMU-77588|reactome:R-MMU-77595|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0034518"(RNA cap binding complex)|ensembl:ENSMUSG00000022774(gene)|ensembl:ENSMUST00000023460(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|refseq:NP_080830.1 - - comment:mint|function:Involved in mediating U snRNA export from the nucleus. Binds to 5' capped mRNA figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:AM46TpEPMDC2Ix3BtphOehTwju410090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q64282 - intact:EBI-8407973|intact:MINT-4124109|uniprotkb:Q99L77|ensembl:ENSMUSP00000099888 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ifit1_mouse(display_long)|uniprotkb:Ifit1(gene name)|psi-mi:Ifit1(display_short)|uniprotkb:Garg16(gene name synonym)|uniprotkb:Glucocorticoid-attenuated response gene 16 protein(gene name synonym)|uniprotkb:Ifi56(gene name synonym)|uniprotkb:Interferon-induced 56 kDa protein(gene name synonym)|uniprotkb:Isg56(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_032357.2|ensembl:ENSMUSG00000034459(gene)|ensembl:ENSMUST00000102824(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0009617"(response to bacterium)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q64282 - - comment:mint figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:JkhvoGmwqpo/NNj0zpx5vScjgro10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q91WK2 - intact:EBI-7466721|intact:MINT-4098428|ensembl:ENSMUSP00000022925 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:eif3h_mouse(display_long)|uniprotkb:Eif3h(gene name)|psi-mi:Eif3h(display_short)|uniprotkb:Eif3s3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_542366.1|ensembl:ENSMUSG00000022312(gene)|ensembl:ENSMUST00000022925(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:Q91WK2|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 - - comment:mint|function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. Associates with the p170 subunit of EIF3 figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:mKyE784VSiEMqBaCyG2Vt9FhynM10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q3UKJ6 - intact:EBI-8572937|intact:MINT-8174140 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q3ukj6_mouse(display_long)|uniprotkb:Dhx15(gene name)|psi-mi:Dhx15(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR007502(Helicase-associated region)|interpro:IPR027417|refseq:NP_031865.2|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR044756 - - comment:mint figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:3ypGFohz40OvVMkbdam/EUAw9hc10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q99MR6 - intact:EBI-6908591|ensembl:ENSMUSP00000043123|uniprotkb:Q3UD04|uniprotkb:Q5D042|uniprotkb:Q8VEE6|uniprotkb:Q99MR4|uniprotkb:Q99MR5|uniprotkb:Q99MR7 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:srrt_mouse(display_long)|uniprotkb:Srrt(gene name)|psi-mi:Srrt(display_short)|uniprotkb:Ars2(gene name synonym)|uniprotkb:Asr2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:XP_006504692.1|ensembl:ENSMUSG00000037364(gene)|ensembl:ENSMUST00000040873(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q99MR6|reactome:R-MMU-6807505|reactome:R-MMU-72163|refseq:NP_001103379.1|refseq:NP_001103380.1|refseq:NP_113582.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:bN5sDa7ldVbikff0n+wySOIeGrE10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q497K3 - intact:EBI-20627624 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q497k3_mouse(display_long)|uniprotkb:Snrpf(gene name)|psi-mi:Snrpf(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_081522.1|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034100|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q14AF6 - intact:EBI-20627606 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q14af6_mouse(display_long)|uniprotkb:SNRPD2(gene name synonym)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:Snrpd2(gene name)|psi-mi:Snrpd2(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_081219.1|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:P27048 - intact:EBI-309845|uniprotkb:Q3UJT1|ensembl:ENSMUSP00000099488 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:rsmb_mouse(display_long)|uniprotkb:Snrpb(gene name)|psi-mi:Snrpb(display_short)|uniprotkb:Sm protein B(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_033251.1|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007420"(brain development)|go:"GO:0034709"(methylosome)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:1990446"(U1 snRNP binding)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN)|mint:P27048|reactome:R-MMU-111367|reactome:R-MMU-191859|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-73856|reactome:R-MMU-77588|ensembl:ENSMUSG00000027404(gene)|ensembl:ENSMUST00000103199(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:HdsrtiDvbyp7PS28aVRTvH0SecY10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q62376 - intact:EBI-6665659|ensembl:ENSMUSP00000074160|uniprotkb:Q3UIW4 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ru17_mouse(display_long)|uniprotkb:Snrp70(gene name synonym)|uniprotkb:Snrnp70(gene name)|psi-mi:Snrnp70(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR022023|interpro:IPR034143|interpro:IPR035979|mint:Q62376|reactome:R-MMU-72163|ensembl:ENSMUST00000074575(transcript)|ensembl:ENSMUSG00000063511(gene)|refseq:XP_006540795.1|refseq:NP_033250.3 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:UaERmiQE+jdLT8Z9NzNWTCBE7dQ10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q549F9 - intact:EBI-20627589 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q549f9_mouse(display_long)|uniprotkb:Smn1(gene name)|psi-mi:Smn1(display_short)|uniprotkb:Smn(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_035550.1|interpro:IPR010304(Survival motor neuron)|interpro:IPR002999(Tudor)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:cTFjZc/daUP5J6lWPrCVM5ZsGeU10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q561N5 - intact:EBI-20627573 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q561n5_mouse(display_long)|uniprotkb:Rps18(gene name)|psi-mi:Rps18(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_035426.1|interpro:IPR027437|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:yOHgKM/BuvgGdqp1OEVPeuiABg810090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q0VGU2 - intact:EBI-20627563 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q0vgu2_mouse(display_long)|uniprotkb:Ptma(gene name)|psi-mi:Ptma(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) interpro:IPR004931(Prothymosin/parathymosin)|refseq:NP_032998.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:U3aCwQANGkMzCFFMOGYx4L4V3LI10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q3UIA1 - intact:EBI-20627540 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q3uia1_mouse(display_long)|uniprotkb:Nelfe(gene name)|psi-mi:Nelfe(display_short)|uniprotkb:Rdbp(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|refseq:NP_001039328.1|refseq:NP_001039329.1|refseq:NP_613046.2|interpro:IPR033102|interpro:IPR034637|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR000504(RNA recognition motif, RNP-1) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:o5TFn7rnSSztj/Uc0nLTZUgF+7410090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q922L6 - intact:EBI-20627520|ensembl:ENSMUSP00000104703|uniprotkb:Q9QXD0|uniprotkb:A2AQ05|uniprotkb:Q9QXC8|uniprotkb:Q9QXC9 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:nelfd_mouse(display_long)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:Nelfcd(gene name)|psi-mi:Nelfcd(display_short)|uniprotkb:Nelfd(gene name synonym)|uniprotkb:Th1(gene name synonym)|uniprotkb:Th1l(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSMUST00000109075(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-75955|ensembl:ENSMUSG00000016253(gene)|refseq:NP_065605.2 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:yqgQ6U6jo6gca4abr6D0VRnZ0m410090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q8C4Y3 - intact:EBI-20627504|uniprotkb:A0A0X1KG62|uniprotkb:Q69ZP4|uniprotkb:Q99J41|uniprotkb:Q9JJA5 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:nelfb_mouse(display_long)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:MNCb-5210(orf name)|uniprotkb:Nelfb(gene name)|psi-mi:Nelfb(display_short)|uniprotkb:Cobra1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-75955|refseq:NP_067368.3|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|refseq:NP_001297086.1|interpro:IPR010405(Cofactor of BRCA1) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:24mGjegYXUrbouPfqAdD0SKA9ZU10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q3UYV9 - intact:EBI-16747696|ensembl:ENSMUSP00000030014|uniprotkb:B1AWH4|uniprotkb:Q3TEM1|uniprotkb:Q7TNE8 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ncbp1_mouse(display_long)|uniprotkb:Ncbp1(gene name)|psi-mi:Ncbp1(display_short)|uniprotkb:Cbp80(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-674695|ensembl:ENSMUSG00000028330(gene)|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|ensembl:ENSMUST00000030014(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|reactome:R-MMU-72163|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|reactome:R-MMU-72165|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|reactome:R-MMU-72187|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|rcsb pdb:3UKZ|rcsb pdb:3UL0|reactome:R-MMU-111367|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-72203|reactome:R-MMU-73856|reactome:R-MMU-77588|reactome:R-MMU-77595|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_001028373.2 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:RdI2wWDaGaAlkGgU1c0ZDb49DFs10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q64345 - intact:EBI-644819|uniprotkb:Q99L62|ensembl:ENSMUSP00000099889 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ifit3_mouse(display_long)|uniprotkb:Glucocorticoid-attenuated response gene 49 protein(gene name synonym)|uniprotkb:IRG2(gene name synonym)|uniprotkb:Ifit3(gene name)|psi-mi:Ifit3(display_short)|uniprotkb:Garg49(gene name synonym)|uniprotkb:Ifi49(gene name synonym)|uniprotkb:Isg49(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_034631.1|ensembl:ENSMUSG00000074896(gene)|ensembl:ENSMUST00000102825(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0009617"(response to bacterium)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:OjoF7slFjr0nHUw1i2WS1a2i70810090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q6GTM0 - intact:EBI-20627484|ensembl:ENSMUSP00000099890 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q6gtm0_mouse(display_long)|uniprotkb:Ifit2(gene name)|psi-mi:Ifit2(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSMUSG00000045932(gene)|ensembl:ENSMUST00000102826(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009615"(response to virus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024124|refseq:NP_032358.1|refseq:XP_006526768.1|refseq:XP_006526769.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:mBpJ3ajpfpATeCfWso4qxJ0a8qs10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:B1AVP5 - intact:EBI-20627473|ensembl:ENSMUSP00000093971 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:b1avp5_mouse(display_long)|uniprotkb:Gemin8(gene name)|psi-mi:Gemin8(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSMUSG00000040621(gene)|ensembl:ENSMUST00000096252(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0032797"(SMN complex)|interpro:IPR034754|refseq:NP_001297653.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:MPuG5yqgCuQKdYCoMFxR32wnybA10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q9CX53 - intact:EBI-309855|uniprotkb:Q3TIW7|uniprotkb:Q9CQI0|uniprotkb:Q9CXC5|ensembl:ENSMUSP00000063554 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:gemi6_mouse(display_long)|uniprotkb:Gemin6(gene name)|psi-mi:Gemin6(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_080329.1|ensembl:ENSMUSG00000055760(gene)|ensembl:ENSMUST00000069486(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|reactome:R-MMU-191859|refseq:XP_011244883.1|refseq:XP_011244884.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:b5Gl6NEvbqFO8lWM8O5c6j0SybE10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q8BX17 - intact:EBI-2550292|uniprotkb:Q3UPH2|ensembl:ENSMUSP00000036603 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:gemi5_mouse(display_long)|uniprotkb:Gemin5(gene name)|psi-mi:Gemin5(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSMUSG00000037275(gene)|ensembl:ENSMUST00000035604(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0016604"(nuclear body)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0032797"(SMN complex)|go:"GO:0034718"(SMN-Gemin2 complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|reactome:R-MMU-191859|refseq:NP_001160141.1|refseq:NP_001160142.1|refseq:NP_001160143.1|refseq:NP_766146.2 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:a2dQ9yhjRVYev2Iml4Zgj8PQi6s10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q6P6L6 - intact:EBI-20627451|ensembl:ENSMUSP00000099558 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q6p6l6_mouse(display_long)|uniprotkb:Gemin4(gene name)|psi-mi:Gemin4(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSMUSG00000049396(gene)|ensembl:ENSMUST00000102500(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR033265|reactome:R-MMU-191859|refseq:NP_796341.2 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:kK2cOIAJeGYT8WtGCXPJdG+Vk2o10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q9CQQ4 - intact:EBI-9989405|uniprotkb:Q9DAD7|ensembl:ENSMUSP00000021379 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:gemi2_mouse(display_long)|uniprotkb:Gemin2(gene name)|psi-mi:Gemin2(display_short)|uniprotkb:Sip1(gene name synonym)|uniprotkb:Component of gems 2(gene name synonym)|uniprotkb:Survival of motor neuron protein-interacting protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_079932.2|ensembl:ENSMUSG00000060121(gene)|ensembl:ENSMUST00000021379(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR017364(Survival of motor neuron protein interacting, gemin2)|interpro:IPR035426|reactome:R-MMU-191859 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:O/XmjNomuDGT/9w6+0dyHVuvaEM10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q9DBC3 - intact:EBI-20627423|ensembl:ENSMUSP00000024816|uniprotkb:Q8C7V0|uniprotkb:Q6A0D5|uniprotkb:Q3U3G5|uniprotkb:Q3U7Y9 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:cmtr1_mouse(display_long)|uniprotkb:Cap methyltransferase 1(gene name synonym)|uniprotkb:Cap1 2'O-ribose methyltransferase 1(gene name synonym)|uniprotkb:FtsJ methyltransferase domain-containing protein 2(gene name synonym)|uniprotkb:Cmtr1(gene name)|psi-mi:Cmtr1(display_short)|uniprotkb:Ftsjd2(gene name synonym)|uniprotkb:Kiaa0082(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSMUSG00000024019(gene)|ensembl:ENSMUST00000024816(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0080009"(mRNA methylation)|go:"GO:0097309"(cap1 mRNA methylation)|interpro:IPR000467(D111/G-patch)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR025816|interpro:IPR029063|interpro:IPR030376|refseq:NP_083067.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:ZHhPGG2u+shSMCCxpct7Cbu/6Lw10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q80XI3 - intact:EBI-11664146|uniprotkb:Q6GQV5|uniprotkb:Q80Y69|uniprotkb:Q8BJ68|uniprotkb:Q8BQF3|uniprotkb:Q8C6Q3|uniprotkb:Q8CIH0 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:if4g3_mouse(display_long)|uniprotkb:Eif4g3(gene name)|psi-mi:Eif4g3(display_short)|uniprotkb:eIF-4-gamma II(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) interpro:IPR037585|refseq:NP_766291.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|reactome:R-MMU-1169408|go:"GO:0000339"(RNA cap binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060903"(positive regulation of meiosis I) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:rZHNyp9tf03rooxy3bm2VgmUpBI10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:E9PVC6 - intact:EBI-20627407|ensembl:ENSMUSP00000111117 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:e9pvc6_mouse(display_long)|uniprotkb:Eif4g1(gene name)|psi-mi:Eif4g1(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSMUSG00000045983(gene)|ensembl:ENSMUST00000115457(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:kPbSKgVLiE2nZfSAiXoQh9WLISg10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q9EST3 - intact:EBI-20627369|ensembl:ENSMUSP00000105676|ensembl:ENSMUSP00000136768|uniprotkb:Q8CFW0|uniprotkb:Q9CSS3 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:4et_mouse(display_long)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)|uniprotkb:Eif4enif1(gene name)|psi-mi:Eif4enif1(display_short)|uniprotkb:Clast4(gene name synonym)|uniprotkb:CD40 ligand-activated specific transcript 4(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) ensembl:ENSMUSG00000020454(gene)|ensembl:ENSMUST00000110049(transcript)|ensembl:ENSMUST00000179770(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|refseq:NP_001160019.1|refseq:NP_001160020.1|refseq:NP_001160021.1|refseq:NP_076232.2|refseq:XP_006514904.1|refseq:XP_006514905.1|refseq:XP_006514906.1|refseq:XP_006514907.1|refseq:XP_017170295.1 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:1IGtA72eTlrdZmqQBEroJ3a2JXo10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q60876 - intact:EBI-398674|uniprotkb:Q3TDS8|uniprotkb:Q9CZ40|ensembl:ENSMUSP00000033880 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:4ebp1_mouse(display_long)|uniprotkb:Eif4ebp1(gene name)|psi-mi:Eif4ebp1(display_short)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_031944.3|dip:DIP-32577N|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|interpro:IPR037582|reactome:R-MMU-166208|reactome:R-MMU-72662|ensembl:ENSMUSG00000031490(gene)|ensembl:ENSMUST00000033880(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0030324"(lung development)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071456"(cellular response to hypoxia) - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:EYSRK9c019DQ14TAyF1cvmdVll410090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q3TK95 - intact:EBI-20627345 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:q3tk95_mouse(display_long)|uniprotkb:Eif4e(gene name)|psi-mi:Eif4e(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0000932"(P-body)|refseq:NP_001300909.1|refseq:NP_031943.3|interpro:IPR023398|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:DnMmfgiMq6RHbSuRPwy/TaoeySU10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q8BZR9 - intact:EBI-11519402|uniprotkb:Q3TNF4|uniprotkb:Q3TQ96|uniprotkb:Q4G0C3|uniprotkb:Q8BMB1|uniprotkb:Q9CRM6|uniprotkb:Q9CS93|uniprotkb:Q9D0G9|uniprotkb:Q9DBT0|ensembl:ENSMUSP00000021135 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ncbp3_mouse(display_long)|uniprotkb:Ncbp3(gene name)|psi-mi:Ncbp3(display_short) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_080094.3|ensembl:ENSMUSG00000020783(gene)|ensembl:ENSMUST00000021135(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:E6dFFHdJMCG4pyGbRgLg8gvyxr410090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-20623174 uniprotkb:Q9JJY4 - intact:EBI-944496|uniprotkb:Q059Z6|uniprotkb:Q9JIK4|ensembl:ENSMUSP00000088176 psi-mi:cvhsa-oligo(display_short)|psi-mi:EBI-20623174(display_long) psi-mi:ddx20_mouse(display_long)|uniprotkb:Ddx20(gene name)|psi-mi:Ddx20(display_short)|uniprotkb:Dp103(gene name synonym)|uniprotkb:Gemin3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym)|uniprotkb:Regulator of steroidogenic factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gebhardt et al. (2015) pubmed:26382858|imex:IM-26480 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-20627001|imex:IM-26480-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) genbank identifier:JQ316196(see-also) refseq:NP_059093.3|refseq:XP_006501764.1|ensembl:ENSMUSG00000027905(gene)|ensembl:ENSMUST00000090680(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9JJY4|reactome:R-MMU-191859 - - - figure legend:Fig. 2A, Data S1, Fig. S1|comment:a similar interaction was detected with Human THP-1 lysates.|comment:Proteins identified by LC-MS/MS from lysates of RAW264.7 macrophages after affinity purification with synthetic RNA baits bearing a 5’cap|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/17 2018/07/18 - rogid:qoEKTrnCV+OBWfbeNBdVTUHAArU10090 - false biotin tag:?-?|uncategorized protein modification:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)