#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P51957-1	uniprotkb:Q3V6T2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2266839|uniprotkb:A1IGE7|uniprotkb:Q53SF1|uniprotkb:Q581G3|uniprotkb:Q5HYD0|uniprotkb:Q7Z339|uniprotkb:Q7Z3C5|uniprotkb:B7ZM78|uniprotkb:C9JG83|ensembl:ENSP00000410608|ensembl:ENSP00000495919	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:grdn_human(display_long)|uniprotkb:CCDC88A(gene name)|psi-mi:CCDC88A(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:GRDN(gene name synonym)|uniprotkb:KIAA1212(gene name synonym)|uniprotkb:Girders of actin filament(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 88A(gene name synonym)|uniprotkb:Akt phosphorylation enhancer(gene name synonym)|uniprotkb:Hook-related protein 1(gene name synonym)|uniprotkb:G alpha-interacting vesicle-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011531267.1|refseq:XP_011531268.1|refseq:XP_011531269.1|refseq:NP_001129069.1|refseq:NP_060554.3|refseq:NP_001241872.1|dip:DIP-50784N|ensembl:ENSG00000115355(gene)|ensembl:ENST00000436346(transcript)|ensembl:ENST00000642200(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030142"(COPI-coated Golgi to ER transport vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0061024"(membrane organization)|go:"GO:1903566"(positive regulation of protein localization to cilium)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR027717|interpro:IPR036872|interpro:IPR043936|rcsb pdb:6MHF|reactome:R-HSA-9696264|reactome:R-HSA-9696273|go:"GO:0072660"(maintenance of protein location in plasma membrane)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:6kUpfRsRH31AqsM5d3q6mybkgdw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O14514	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1995178|ensembl:ENSP00000313046|ensembl:ENSP00000430945	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:agrb1_human(display_long)|uniprotkb:ADGRB1(gene name)|psi-mi:ADGRB1(display_short)|uniprotkb:BAI1(gene name synonym)|uniprotkb:Brain-specific angiogenesis inhibitor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011515501.1|refseq:NP_001693.2|dip:DIP-40884N|ensembl:ENSG00000181790(gene)|ensembl:ENST00000323289(transcript)|ensembl:ENST00000517894(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045087"(innate immune response)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR008077(GPCR, family 2, brain-specific angiogenesis inhibitor)|interpro:IPR017981|interpro:IPR032471|interpro:IPR036383|interpro:IPR036445|interpro:IPR043838|mint:O14514	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:CM2mofUrH0mg1fj03UflXDeFyvs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q7Z3Z4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-528601|uniprotkb:Q68CZ4|uniprotkb:Q8N8G9|uniprotkb:Q8N9V8|uniprotkb:Q8NEH2|uniprotkb:B4DEG5|ensembl:ENSP00000299001	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:piwl4_human(display_long)|uniprotkb:PIWIL4(gene name)|psi-mi:PIWIL4(display_short)|uniprotkb:HIWI2(gene name synonym)|uniprotkb:PIWI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_689644.2|ensembl:ENST00000299001(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043186"(P granule)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071547"(piP-body)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7Z3Z4|reactome:R-HSA-5601884|ensembl:ENSG00000134627(gene)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wcvVa2Z0CqemBieD8X12ovmdfpc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8NHM5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q14676	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P16104	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8TB40	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-7131019|ensembl:ENSP00000414558|uniprotkb:Q9H9E0|intact:MINT-3044114|uniprotkb:B4DDH7	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:abhd4_human(display_long)|uniprotkb:ABHD4(gene name)|psi-mi:ABHD4(display_short)|uniprotkb:Alpha/beta-hydrolase 4(gene name synonym)|uniprotkb:Alpha/beta hydrolase domain-containing protein 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000100439(gene)|ensembl:ENST00000428304(transcript)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0036152"(phosphatidylethanolamine acyl-chain remodeling)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070292"(N-acylphosphatidylethanolamine metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|reactome:R-HSA-1482839|go:"GO:0005739"(mitochondrion)|refseq:NP_071343.2	-	-	comment:mint|comment:homomint|function:"Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine"	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:HPj5cWLUqWoHx67HS+XhF82GCGY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q03169	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-7954198|uniprotkb:Q86VI0|intact:MINT-7944790|ensembl:ENSP00000332326|ensembl:ENSP00000452634	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tnap2_human(display_long)|uniprotkb:TNFAIP2(gene name)|psi-mi:TNFAIP2(display_short)|uniprotkb:Primary response gene B94 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011535416.1|refseq:NP_006282.2|ensembl:ENSG00000185215(gene)|ensembl:ENST00000333007(transcript)|ensembl:ENST00000560869(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0005615"(extracellular space)|go:"GO:0006887"(exocytosis)|go:"GO:0030154"(cell differentiation)|go:"GO:0051601"(exocyst localization)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|mint:Q03169	-	-	comment:mint|comment:homomint	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:cyKWiHQn2RwDMMJYHyM2/LcDeP49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13402	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-7417855|uniprotkb:Q13321|uniprotkb:Q92822|intact:MINT-1895479|uniprotkb:Q14785|uniprotkb:Q92821|uniprotkb:F8VUN5|uniprotkb:P78427|uniprotkb:B9A011|ensembl:ENSP00000386331	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:myo7a_human(display_long)|uniprotkb:MYO7A(gene name)|psi-mi:MYO7A(display_short)|uniprotkb:USH1B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000251.3|refseq:NP_001120652.1|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042470"(melanosome)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|go:"GO:0034613"(cellular protein localization)|interpro:IPR038185|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000137474(gene)|ensembl:ENST00000409709(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|interpro:IPR041794|mint:Q13402|rcsb pdb:5MV9|reactome:R-HSA-2453902|reactome:R-HSA-9662360|reactome:R-HSA-9662361|interpro:IPR041793	-	-	comment:mint|function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa might play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it might maintain the rigidity of stereocilia during the dynamic movements of the bundle. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity|function:"Defects in MYO7A are the cause of Usher syndrome type 1B (USH1B) [MIM:276900]. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa and sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH1 is characterized by profound congenital sensorineural deafness, absent vestibular function and prepubertal onset of progressive retinitis pigmentosa leading to blindness"|function:"Defects in MYO7A are the cause of non-syndromic sensorineural deafness autosomal recessive type 2 (DFNB2) [MIM:600060]; also called neurosensory non-syndromic recessive deafness 2 (NSRD2). DFNB2 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information{EC15,EC16}"|function:"Defects in MYO7A are the cause of non-syndromic sensorineural deafness autosomal dominant type 11 (DFNA11) [MIM:601317]"	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:OwxpV+yOnwipkRuEY1IAUY3i2/w9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:A0AVK6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-7779316|ensembl:ENSP00000250024|ensembl:ENSP00000434199|ensembl:ENSP00000481103|uniprotkb:Q8N340|uniprotkb:Q5BKY4|intact:MINT-6541611|uniprotkb:Q9H5M0|uniprotkb:Q3C1U6|uniprotkb:Q2VPJ3|uniprotkb:A8K9H3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:e2f8_human(display_long)|uniprotkb:E2F8(gene name)|psi-mi:E2F8(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|mint:A0AVK6|rcsb pdb:4YO2|reactome:R-HSA-6804116|go:"GO:0070365"(hepatocyte differentiation)|ensembl:ENSG00000129173(gene)|ensembl:ENST00000250024(transcript)|ensembl:ENST00000527884(transcript)|ensembl:ENST00000620009(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|refseq:NP_001243301.1|refseq:NP_001243300.1|refseq:NP_078956.2	-	-	function:Inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Modulates the activity of other E2F proteins, such as E2F1, probably by competing or displacing activating E2Fs from promoter binding|comment:mint	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:8RCzz+HuzFPNJ4soR6lxKkq17BU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86XX4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-7967766|uniprotkb:Q8NAU7|intact:UNK-5504239|uniprotkb:Q86UZ4|uniprotkb:Q9H6N9|uniprotkb:Q8N3U9|uniprotkb:Q9P228|uniprotkb:Q96JW7|uniprotkb:A2RRR8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:fras1_human(display_long)|uniprotkb:Fraser syndrome 1 protein(gene name synonym)|uniprotkb:FRAS1(gene name)|psi-mi:FRAS1(display_short)|uniprotkb:KIAA1500(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR038081|interpro:IPR039005|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR006212(Furin-like repeat)|refseq:NP_001159605.1|refseq:NP_079350.5|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)	-	-	comment:mint|function:"Defects in FRAS1 are a cause of Fraser syndrome [MIM:219000]. It is a multisystem malformation usually comprising cryptophthalmos, cutaneous syndactyly, ear abnormalities, renal agenesis and congenital heart defects"	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:nJ/4j001Lihre1n+/qvt3K6k1rg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UMZ2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-7240490|uniprotkb:Q6ZT17|uniprotkb:B7ZKZ3|uniprotkb:Q17RI2|uniprotkb:Q5BKU5|intact:MINT-126209|uniprotkb:B7ZKZ2|intact:EBI-28973092|ensembl:ENSP00000480288|ensembl:ENSP00000483453|uniprotkb:A8MWU4	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:synrg_human(display_long)|uniprotkb:SYNG(gene name synonym)|uniprotkb:Gamma-synergin(gene name synonym)|uniprotkb:AP1GBP1(gene name synonym)|uniprotkb:AP1 subunit gamma-binding protein 1(gene name synonym)|uniprotkb:SYNRG(gene name)|psi-mi:SYNRG(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENST00000610513|ensembl:ENSP00000478707|ensembl:ENSP00000483453|ensembl:ENST00000613407|ensembl:ENSP00000483152|ensembl:ENST00000614941|ensembl:ENSP00000481151|ensembl:ENST00000616179|ensembl:ENSP00000482962|ensembl:ENST00000618176|ensembl:ENSP00000482597|ensembl:ENSP00000480288|ensembl:ENST00000619541|ensembl:ENSP00000477885|ensembl:ENST00000621136|ensembl:ENSP00000484529|ensembl:ENST00000622045|ensembl:ENSP00000483063|ensembl:ENST00000632841|ensembl:ENSP00000487672|ensembl:ENST00000633429|ensembl:ENSP00000488473|refseq:NP_001157016.1|refseq:NP_542117.3|refseq:NP_001157019.1|refseq:NP_009178.3|refseq:NP_001157017.1|ensembl:ENSG00000274047(gene)|ensembl:ENSG00000275066(gene)|ensembl:ENST00000612223(transcript)|ensembl:ENST00000618402(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR011992(EF-Hand type)|interpro:IPR039656|rcsb pdb:2MX7|refseq:XP_016879582.1|refseq:NP_001157018.1|refseq:NP_942583.1	-	-	comment:mint|function:"May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins"	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:nsmKdl2koDl/Xk/bUBXCOFxrml49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86T75	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-9641271|uniprotkb:Q5RGN0|uniprotkb:B7Z7R4|uniprotkb:B1AKG1|ensembl:ENSP00000477509|ensembl:ENSP00000484213|ensembl:ENSP00000507808	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nbpfb_human(display_long)|uniprotkb:NBPF11(gene name)|psi-mi:NBPF11(display_short)|uniprotkb:NBPF24(gene name synonym)|uniprotkb:Neuroblastoma breakpoint family member 24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001095133.3|refseq:NP_899228.4|dip:DIP-47328N|ensembl:ENSG00000263956(gene)|ensembl:ENST00000614015(transcript)|ensembl:ENST00000615281(transcript)|ensembl:ENST00000682118(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR010630(Protein of unknown function DUF1220)|mint:Q86T75	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:WdD1ZPPL02ZLm85MPbBMxZ3lTkM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13296	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-9058786|uniprotkb:Q86WH8|uniprotkb:A1A522|ensembl:ENSP00000227918	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sg2a2_human(display_long)|uniprotkb:SCGB2A2(gene name)|psi-mi:SCGB2A2(display_short)|uniprotkb:MGB1(gene name synonym)|uniprotkb:Mammaglobin-1(gene name synonym)|uniprotkb:Secretoglobin family 2A member 2(gene name synonym)|uniprotkb:UGB2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002402.1|ensembl:ENSG00000110484(gene)|ensembl:ENST00000227918(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0030521"(androgen receptor signaling pathway)|interpro:IPR016126(Secretoglobin)|interpro:IPR035960	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Br8yIoqqRyImivfEZgYKBpaQ3Cc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N6M5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11319658|uniprotkb:B4DY77|uniprotkb:Q9NZA7|uniprotkb:Q5RL81|uniprotkb:Q96RE6|uniprotkb:Q53T95|ensembl:ENSP00000252505	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:allc_human(display_long)|uniprotkb:ALLC(gene name)|psi-mi:ALLC(display_short)|uniprotkb:Allantoate amidinohydrolase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_060906.3|interpro:IPR015908(Allantoicase region)|ensembl:ENSG00000151360(gene)|ensembl:ENST00000252505(transcript)|go:"GO:0000256"(allantoin catabolic process)|go:"GO:0004037"(allantoicase activity)|interpro:IPR005164(Allantoicase)|interpro:IPR008979(Galactose-binding like)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:grL+pmf/GbO6q/vMVLgEa3T4QLg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BRS2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-7307838|intact:MINT-1630868|uniprotkb:Q96NV9|uniprotkb:B2RB28|uniprotkb:Q8NDC8|ensembl:ENSP00000369162	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:riok1_human(display_long)|uniprotkb:RIOK1(gene name)|psi-mi:RIOK1(display_short)|uniprotkb:RIO kinase 1(gene name synonym)|uniprotkb:RIO1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_113668.2|ensembl:ENSG00000124784(gene)|ensembl:ENST00000379834(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034708"(methyltransferase complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000687(RIO kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017407(Serine/threonine-protein kinase Rio1)|interpro:IPR018935|rcsb pdb:4OTP|rcsb pdb:6G5I|rcsb pdb:6V0N|rcsb pdb:6ZV6|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|reactome:R-HSA-6791226	-	-	comment:mint|comment:homomint	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:1Da5yQeq0zHVuRviiNdxy8/3TqI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q03468	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-295284|uniprotkb:Q5W0L9|uniprotkb:D3DX94|intact:EBI-11058424|uniprotkb:E7EV46|intact:EBI-28985869|ensembl:ENSP00000348089	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ercc6_human(display_long)|uniprotkb:ERCC6(gene name)|psi-mi:ERCC6(display_short)|uniprotkb:CSB(gene name synonym)|uniprotkb:ATP-dependent helicase ERCC6(gene name synonym)|uniprotkb:Cockayne syndrome protein CSB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001333369.1|refseq:NP_000115.1|ensembl:ENSP00000348089|dip:DIP-193N|ensembl:ENSG00000225830(gene)|ensembl:ENST00000355832(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000303"(response to superoxide)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043044"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070615"|go:"GO:0090734"(site of DNA damage)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|rcsb pdb:4CVO|reactome:R-HSA-427389|reactome:R-HSA-5250924|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-73762	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3UBZr8QjneuE87ikC9SfFXUfHlg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O00322	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-14031976|uniprotkb:Q3KNU5|uniprotkb:Q3KNU6|ensembl:ENSP00000222275|ensembl:ENSP00000483176	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:upk1a_human(display_long)|uniprotkb:UPK1A(gene name)|psi-mi:UPK1A(display_short)|uniprotkb:TSPAN21(gene name synonym)|uniprotkb:Uroplakin Ia(gene name synonym)|uniprotkb:Tetraspanin-21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001268372.1|refseq:NP_008931.1|ensembl:ENSG00000105668(gene)|ensembl:ENST00000222275(transcript)|ensembl:ENST00000617999(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034765	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/W9BzFoQXsagQQwLySUl280GnQk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9ULU8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-724083|uniprotkb:A6NF60|ensembl:ENSP00000373215|uniprotkb:Q13339|uniprotkb:Q6GQQ6|uniprotkb:Q8N2Z5|uniprotkb:Q8N3M7|uniprotkb:Q8NFR0|uniprotkb:Q96BC2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:caps1_human(display_long)|uniprotkb:Calcium-dependent activator protein for secretion 1(gene name synonym)|uniprotkb:CADPS(gene name)|psi-mi:CADPS(display_short)|uniprotkb:CAPS(gene name synonym)|uniprotkb:CAPS1(gene name synonym)|uniprotkb:KIAA1121(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003707.2|refseq:NP_899630.1|refseq:NP_899631.1|ensembl:ENST00000383710(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099012"(neuronal dense core vesicle membrane)|go:"GO:1990504"(dense core granule exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR033227|rcsb pdb:1WI1|ensembl:ENSG00000163618(gene)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:hQl0T9hJM7/iepE3eQvnwweZ+Pg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q02641	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-947514|uniprotkb:O15331|uniprotkb:Q02639|uniprotkb:Q02640|uniprotkb:Q9C085|uniprotkb:Q8N3X9|uniprotkb:Q9UD79|uniprotkb:A8K114|ensembl:ENSP00000377840	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cacb1_human(display_long)|uniprotkb:CACNB1(gene name)|psi-mi:CACNB1(display_short)|uniprotkb:CACNLB1(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000714.3|refseq:NP_954855.1|refseq:NP_954856.1|ensembl:ENSG00000067191(gene)|ensembl:ENST00000394303(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005443(Voltage-dependent calcium channel, L-type, beta-1 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|mint:Q02641|reactome:R-HSA-112308|reactome:R-HSA-419037|reactome:R-HSA-5576892|reactome:R-HSA-5576893	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:nP0QYe6Gr+aIneTmyLWfPuvMEfk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9C0F0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721363|ensembl:ENSP00000269197|uniprotkb:Q6ZMX6|uniprotkb:Q96MU3|uniprotkb:Q9UFC5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:asxl3_human(display_long)|uniprotkb:Additional sex combs-like protein 3(gene name synonym)|uniprotkb:ASXL3(gene name)|psi-mi:ASXL3(display_short)|uniprotkb:KIAA1713(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000269197|ensembl:ENSG00000141431(gene)|ensembl:ENST00000269197(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024818|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|refseq:NP_085135.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:6Z9gf4yZ5hSK9tEl5NFKLRvFBgs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q14CM0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-311279|uniprotkb:O15032|uniprotkb:A8K0X9|intact:EBI-28986006|ensembl:ENSP00000370057	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:frpd4_human(display_long)|uniprotkb:FRMPD4(gene name)|psi-mi:FRMPD4(display_short)|uniprotkb:KIAA0316(gene name synonym)|uniprotkb:PDZD10(gene name synonym)|uniprotkb:PDZK10(gene name synonym)|uniprotkb:PDZ domain-containing protein 10(gene name synonym)|uniprotkb:PSD-95-interacting regulator of spine morphogenesis(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_055543.2|go:"GO:0032991"(protein-containing complex)|go:"GO:0043197"(dendritic spine)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|interpro:IPR041779|mint:Q14CM0|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:7BYJ|ensembl:ENSG00000169933(gene)|ensembl:ENST00000380682(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005856"(cytoskeleton)|ensembl:ENSP00000370057	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:i30LCbRkJu6iYViBTLtHqGCFdXA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BQS2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-13629494|ensembl:ENSP00000363441|uniprotkb:A5D6W8|uniprotkb:Q5VY53|uniprotkb:Q5VY55|uniprotkb:Q7Z439|uniprotkb:Q7Z440	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:syt15_human(display_long)|uniprotkb:SYT15(gene name)|psi-mi:SYT15(display_short)|uniprotkb:Chr10Syt(gene name synonym)|uniprotkb:Synaptotagmin XV(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000204176(gene)|ensembl:ENST00000374321(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR030539|interpro:IPR035892|refseq:NP_114118.2|refseq:NP_852660.1|refseq:XP_006718074.1|refseq:XP_006718160.1|refseq:XP_016872240.1|refseq:XP_016872241.1|refseq:XP_016872510.1|refseq:XP_016872512.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:aq0GM21IYyIP1esQHjhs/l8rsz49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9C0K0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6597578|intact:EBI-28967428|ensembl:ENSP00000349723|uniprotkb:Q9H162	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:bc11b_human(display_long)|uniprotkb:BCL11B(gene name)|psi-mi:BCL11B(display_short)|uniprotkb:CTIP2(gene name synonym)|uniprotkb:RIT1(gene name synonym)|uniprotkb:B-cell CLL/lymphoma 11B(gene name synonym)|uniprotkb:COUP-TF-interacting protein 2(gene name synonym)|uniprotkb:Radiation-induced tumor suppressor gene 1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENST00000345514|ensembl:ENSP00000280435|ensembl:ENSP00000349723|ensembl:ENSG00000127152(gene)|ensembl:ENST00000357195(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043368"(positive T cell selection)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0071678"(olfactory bulb axon guidance)|go:"GO:0097535"(lymphoid lineage cell migration into thymus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9C0K0|refseq:NP_075049.1|refseq:NP_612808.1|refseq:NP_001269166.1|refseq:NP_001269167.1|dip:DIP-44025N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:qwv1arb47L+4NtLkdHByglThsqs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:B1APH4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721343|intact:EBI-28977502|uniprotkb:B1APH5|uniprotkb:B7Z7S5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:zn487_human(display_long)|uniprotkb:KRAB domain only protein 1(gene name synonym)|uniprotkb:ZNF487(gene name)|psi-mi:ZNF487(display_short)|uniprotkb:KRBO1(gene name synonym)|uniprotkb:ZNF487P(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:j9MAhZgV95EH0yh6P1uK7UUwcdU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N5H7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-745980|uniprotkb:Q5HYE5|uniprotkb:Q6UY42|uniprotkb:Q8N6X3|uniprotkb:Q9Y2X5|ensembl:ENSP00000317817|uniprotkb:Q5JU31|uniprotkb:A8K5S8|uniprotkb:E9PG48	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sh2d3_human(display_long)|uniprotkb:SH2D3C(gene name)|psi-mi:SH2D3C(display_short)|uniprotkb:NSP3(gene name synonym)|uniprotkb:Novel SH2-containing protein 3(gene name synonym)|uniprotkb:SH2 domain-containing Eph receptor-binding protein 1(gene name synonym)|uniprotkb:UNQ272/PRO309/PRO34088(orf name)|uniprotkb:Cas/HEF1-associated signal transducer(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001136004.1|refseq:NP_005480.2|refseq:NP_733745.1|refseq:XP_011516419.1|ensembl:ENST00000420366|ensembl:ENSP00000388536|ensembl:ENST00000429553|ensembl:ENSP00000394632|ensembl:ENST00000629203|ensembl:ENSP00000485866|ensembl:ENSP00000362374|ensembl:ENSP00000317817|ensembl:ENST00000373276|ensembl:ENSP00000362373|ensembl:ENST00000373277|ensembl:ENSG00000095370(gene)|ensembl:ENST00000314830(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030424"(axon)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|interpro:IPR000980(SH2 motif)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR023578|interpro:IPR036860|interpro:IPR036964|interpro:IPR044102|rcsb pdb:3T6G|refseq:NP_001136005.1|refseq:NP_001239263.1|refseq:NP_001136006.1|refseq:XP_005251696.1|refseq:XP_016869663.1|dip:DIP-59443N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Ko3fHifx+8U5Sx1N0EpBfm7HZQ49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NWU1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11127977|ensembl:ENSP00000280701	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:oxsm_human(display_long)|uniprotkb:OXSM(gene name)|psi-mi:OXSM(display_short)|uniprotkb:Beta-ketoacyl-ACP synthase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001138863.1|refseq:NP_060367.1|refseq:XP_006713279.1|ensembl:ENSG00000151093(gene)|ensembl:ENST00000280701(transcript)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0051790"(short-chain fatty acid biosynthetic process)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|interpro:IPR000794(Beta-ketoacyl synthase)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR016039(Thiolase-like)|interpro:IPR017568(3-oxoacyl-[acyl-carrier-protein] synthase 2)|interpro:IPR018201|interpro:IPR020841|rcsb pdb:2C9H|rcsb pdb:2IWY|rcsb pdb:2IWZ|refseq:XP_016862202.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:h3Moh2GMnOpmpFCBC2pu1fMW0sU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:A6NHL2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2954795|uniprotkb:Q9H6Z0|uniprotkb:Q4QQJ5|uniprotkb:B4DKL2|ensembl:ENSP00000369784	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tbal3_human(display_long)|uniprotkb:TUBAL3(gene name)|psi-mi:TUBAL3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001165335.1|refseq:NP_079079.1|ensembl:ENSG00000178462(gene)|ensembl:ENST00000380419(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Yr8HihP2hK6YdLc8Xa9edSOOrA09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IWA0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2515097|ensembl:ENSP00000314193|uniprotkb:Q9UIX2|uniprotkb:Q9H9U5|uniprotkb:Q96J10|uniprotkb:Q9H8U8|uniprotkb:Q9H9V8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:wdr75_human(display_long)|uniprotkb:WDR75(gene name)|psi-mi:WDR75(display_short)|uniprotkb:UTP17(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 17 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000115368(gene)|ensembl:ENST00000314761(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_115544.1|refseq:NP_001290025.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:qAYPzmryYALOzvea97t1q/NCsVs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P25940	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2464584|uniprotkb:Q9NZQ6|ensembl:ENSP00000264828	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:co5a3_human(display_long)|uniprotkb:COL5A3(gene name)|psi-mi:COL5A3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_056534.2|ensembl:ENSG00000080573(gene)|ensembl:ENST00000264828(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005588"(collagen type V trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043588"(skin development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:O7028FAYwDbZ9tZ7UlnPomBJrdA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86YS6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-4401730|uniprotkb:A8K4P9|uniprotkb:E9PBQ0|ensembl:ENSP00000319781|ensembl:ENSP00000376981|ensembl:ENSP00000376982|ensembl:ENSP00000376984|ensembl:ENSP00000376985	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rab43_human(display_long)|uniprotkb:RAB43(gene name)|psi-mi:RAB43(display_short)|uniprotkb:RAB41(gene name synonym)|uniprotkb:Ras-related protein Rab-41(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001191816.1|refseq:NP_001191812.1|refseq:NP_001191813.1|refseq:NP_001191814.1|refseq:NP_001191815.1|refseq:NP_940892.1|ensembl:ENSG00000172780(gene)|ensembl:ENST00000315150(transcript)|ensembl:ENST00000393304(transcript)|ensembl:ENST00000393305(transcript)|ensembl:ENST00000393307(transcript)|ensembl:ENST00000393308(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0019068"(virion assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035526"(retrograde transport, plasma membrane to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090382"(phagosome maturation)|go:"GO:1901998"(toxin transport)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2HUP|reactome:R-HSA-6811440|reactome:R-HSA-8873719	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Fnf/WvsSlD/a+UxyrO08zMSjpIo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q93084	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1046185|uniprotkb:O60900|uniprotkb:O60901|uniprotkb:O75501|uniprotkb:O75502|uniprotkb:Q16115|uniprotkb:Q8TEX5|uniprotkb:Q8TEX6|uniprotkb:D3DTJ8|uniprotkb:A8MZG0|uniprotkb:Q6JHX1|ensembl:ENSP00000380234	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:at2a3_human(display_long)|uniprotkb:Calcium pump 3(gene name synonym)|uniprotkb:ATP2A3(gene name)|psi-mi:ATP2A3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_777618.1|refseq:NP_005164.2|refseq:NP_777615.1|refseq:NP_777616.1|refseq:NP_777617.1|refseq:NP_777613.1|refseq:NP_777614.1|ensembl:ENSG00000074370(gene)|ensembl:ENST00000397041(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Nvh6pdcL5m05Wgu5rINDl8bhvDM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P52948	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P59510	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-3893375|uniprotkb:A6NNC9|uniprotkb:J3QT00	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ats20_human(display_long)|uniprotkb:ADAMTS20(gene name)|psi-mi:ADAMTS20(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	reactome:R-HSA-5083635|interpro:IPR036383|refseq:NP_079279.3|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR024079|interpro:IPR012314(Peptidase M12B, GON-ADAMTSs)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR013273(Peptidase M12B, ADAM-TS)|reactome:R-HSA-5173214|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045636"(positive regulation of melanocyte differentiation)|interpro:IPR041645	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:1kXdG5SoC5a7eDCCB9HOML40M4w9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IYM0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6269645|uniprotkb:B4DZ15|intact:EBI-28984319|ensembl:ENSP00000257894|uniprotkb:Q8TCP7|uniprotkb:Q9H0L3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:f186b_human(display_long)|uniprotkb:FAM186B(gene name)|psi-mi:FAM186B(display_short)|uniprotkb:C12orf25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000135436(gene)|ensembl:ENST00000257894(transcript)|go:"GO:0032991"(protein-containing complex)|refseq:XP_011537098.1|ensembl:ENSP00000257894|refseq:XP_006719688.1|refseq:NP_115506.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:MEuQQ4I444kV4y1Dsxi3B2xo+8E9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IZ96	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721283|ensembl:ENSP00000405729|intact:EBI-28985356|uniprotkb:Q2PPY5|uniprotkb:Q6PEV5|uniprotkb:Q8IU76|uniprotkb:Q8IU83|uniprotkb:Q8IU86|uniprotkb:Q8IU93|uniprotkb:Q8IZ87|uniprotkb:Q8IZ88|uniprotkb:Q8IZ89|uniprotkb:Q8IZ90|uniprotkb:Q8IZ91|uniprotkb:Q8IZ92|uniprotkb:Q8IZ93|uniprotkb:Q8IZ94|uniprotkb:Q8IZ95|uniprotkb:Q96JC2|uniprotkb:Q96JC3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cklf1_human(display_long)|uniprotkb:Chemokine-like factor superfamily member 1(gene name synonym)|uniprotkb:CMTM1(gene name)|psi-mi:CMTM1(display_short)|uniprotkb:CKLFSF1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENST00000332695|ensembl:ENSP00000331428|ensembl:ENST00000333001|ensembl:ENSP00000331494|ensembl:ENST00000336328|ensembl:ENSP00000337119|ensembl:ENST00000379500|ensembl:ENSP00000368814|ensembl:ENSP00000405729|ensembl:ENST00000528324|ensembl:ENSP00000432398|ensembl:ENST00000528484|ensembl:ENSP00000437079|ensembl:ENSP00000431303|ensembl:ENST00000531885|ensembl:ENSP00000432687|ensembl:ENST00000533078|ensembl:ENSP00000432387|ensembl:ENST00000533666|ensembl:ENSP00000435020|ensembl:ENST00000533915|ensembl:ENSP00000435755|ensembl:ENST00000529386|ensembl:ENSG00000089505(gene)|ensembl:ENST00000457188(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008253(Marvel)|refseq:NP_443725.3|refseq:NP_851785.2|refseq:NP_851786.1|refseq:NP_851787.1|refseq:NP_851788.1|refseq:NP_851789.1|refseq:NP_851800.1|refseq:NP_851813.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:yRl8CqhJza5ceChn0YnuyPbBFJc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86UQ4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11725023|uniprotkb:K9LC76|uniprotkb:K9LCX7|uniprotkb:K9LDK8|uniprotkb:K9LDY4|uniprotkb:Q6ZTT7|uniprotkb:Q86WI2|uniprotkb:Q8N248|uniprotkb:K9LC79	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:abcad_human(display_long)|uniprotkb:ABCA13(gene name)|psi-mi:ABCA13(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_689914.3|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR026082|interpro:IPR003439(ABC transporter-like)|interpro:IPR027417|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035627"(ceramide transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|reactome:R-HSA-6798695	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:v0J0W8WEJVj/EBFIYmzg27uQfcQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8WXQ8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721244|ensembl:ENSP00000376907|ensembl:ENSP00000417314|ensembl:ENSP00000418183|ensembl:ENSP00000419025|ensembl:ENSP00000420237|uniprotkb:G3V0G8|uniprotkb:Q6ZNI6|uniprotkb:Q86SE2|uniprotkb:Q86XM3|uniprotkb:Q8NA08	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cbpa5_human(display_long)|uniprotkb:CPA5(gene name)|psi-mi:CPA5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000158525(gene)|ensembl:ENST00000393213(transcript)|ensembl:ENST00000461828(transcript)|ensembl:ENST00000466363(transcript)|ensembl:ENST00000474905(transcript)|ensembl:ENST00000485477(transcript)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR003146(Proteinase inhibitor, carboxypeptidase propeptide)|interpro:IPR034248|interpro:IPR036990|refseq:NP_001120913.1|refseq:NP_001120914.1|refseq:NP_001305152.1|refseq:NP_525124.3|refseq:XP_005250767.1|refseq:XP_005250769.1|refseq:XP_011515000.1|refseq:XP_011515003.1|refseq:XP_011515004.1|refseq:XP_011515005.1|refseq:XP_011515006.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rXRnTWvgCHkq4o0ux6ZHem0YEyI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N4U5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11897462|ensembl:ENSP00000299045|uniprotkb:B2RA65|uniprotkb:G3V1Y9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:t11l2_human(display_long)|uniprotkb:TCP11L2(gene name)|psi-mi:TCP11L2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000166046(gene)|ensembl:ENST00000299045(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR008862(T-complex 11)|refseq:NP_001273191.1|refseq:NP_689985.1|refseq:XP_005268824.1|refseq:XP_005268825.1|refseq:XP_011536431.1|refseq:XP_011536432.1|refseq:XP_016874616.1|refseq:XP_016874617.1|refseq:XP_016874618.1|refseq:XP_016874619.1|refseq:XP_016874620.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:7KIshvYZzF+b9GICRK7W9MWX9d89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UNS1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2212315|intact:EBI-2561400|uniprotkb:B2ZAV0|uniprotkb:O94802|uniprotkb:Q86VM1|uniprotkb:Q8IWH3|ensembl:ENSP00000450607	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tim_human(display_long)|uniprotkb:TIMELESS(gene name)|psi-mi:TIMELESS(display_short)|uniprotkb:TIM(gene name synonym)|uniprotkb:TIM1(gene name synonym)|uniprotkb:TIMELESS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003911.2|refseq:NP_001317224.1|dip:DIP-47395N|ensembl:ENSG00000111602(gene)|ensembl:ENST00000553532(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009582"(detection of abiotic stimulus)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043111"(replication fork arrest)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:1904976"(cellular response to bleomycin)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR006906(Timeless protein)|interpro:IPR007725(Timeless C-terminal)|rcsb pdb:4XHT|rcsb pdb:4XHU|rcsb pdb:4XHW|rcsb pdb:5MQI|rcsb pdb:6T9Q|rcsb pdb:6TAZ|reactome:R-HSA-5693607	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:lFzdtUFz91sT6BcYbkFDEmPU3KU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5TCZ1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2483234|uniprotkb:O43302|uniprotkb:Q5TCZ2|uniprotkb:Q5TDQ8|uniprotkb:D3DR98|ensembl:ENSP00000358789	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:spd2a_human(display_long)|uniprotkb:Tyrosine kinase substrate with five SH3 domains(gene name synonym)|uniprotkb:SH3PXD2A(gene name)|psi-mi:SH3PXD2A(display_short)|uniprotkb:FISH(gene name synonym)|uniprotkb:KIAA0418(gene name synonym)|uniprotkb:SH3MD1(gene name synonym)|uniprotkb:SH3 multiple domains protein 1(gene name synonym)|uniprotkb:Five SH3 domain-containing protein(gene name synonym)|uniprotkb:Adapter protein TKS5(gene name synonym)|uniprotkb:TKS5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_055446.2|refseq:XP_005270351.1|ensembl:ENSG00000107957(gene)|ensembl:ENST00000369774(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030054"(cell junction)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042995"(cell projection)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072675"(osteoclast fusion)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR034917|interpro:IPR035449|interpro:IPR035450|interpro:IPR035452|interpro:IPR035453|interpro:IPR035454|interpro:IPR036028|interpro:IPR036871|interpro:IPR037961|rcsb pdb:2DNU|rcsb pdb:2EGA|rcsb pdb:2EGC|rcsb pdb:2EKH|mint:Q5TCZ1|reactome:R-HSA-8941237|reactome:R-HSA-9013148	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:XnTFFWWCeseePTNypWPnbkI+Y6I9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q7Z589	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6598631|ensembl:ENSP00000334130|ensembl:ENSP00000432327|uniprotkb:Q4G109|uniprotkb:Q8NBU6|uniprotkb:Q8TE50|uniprotkb:Q9H8I9|uniprotkb:Q9NRH0|uniprotkb:B7ZKU0|uniprotkb:B7ZKT8|uniprotkb:B7ZKU2|uniprotkb:Q17RM7	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:emsy_human(display_long)|uniprotkb:EMSY(gene name)|psi-mi:EMSY(display_short)|uniprotkb:C11orf30(gene name synonym)|uniprotkb:GL002(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001287871.1|refseq:NP_001287872.1|refseq:NP_001287873.1|ensembl:ENST00000334736(transcript)|ensembl:ENST00000529032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|interpro:IPR005491(ENT)|interpro:IPR033482|interpro:IPR036142|mint:Q7Z589|rcsb pdb:1UTU|ensembl:ENSG00000158636(gene)|rcsb pdb:1UZ3|rcsb pdb:2FMM|refseq:NP_064578.2|ensembl:ENSP00000433634|ensembl:ENST00000533988|ensembl:ENSP00000434665|ensembl:ENSP00000334130|ensembl:ENST00000524767|ensembl:ENSP00000433205|ensembl:ENST00000525038|ensembl:ENSP00000436968|ensembl:ENST00000525919|ensembl:ENSP00000432010|ensembl:ENSP00000432327|ensembl:ENST00000533248|dip:DIP-29099N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:AlagiKsle+RG5HUine4x/QddsJc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8NGA0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721223|ensembl:ENSP00000444134|uniprotkb:Q6IFJ5|uniprotkb:Q96RA1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:or7g1_human(display_long)|uniprotkb:Olfactory receptor 19-15(gene name synonym)|uniprotkb:Olfactory receptor OR19-8(gene name synonym)|uniprotkb:OR7G1(gene name)|psi-mi:OR7G1(display_short)|uniprotkb:OR7G1P(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000161807(gene)|ensembl:ENST00000541538(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004984"(olfactory receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000725(Olfactory receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-381753|refseq:NP_001005192.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:kr2bd0VFqX1rkoeP1CVy8FDoriU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9C000	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1220518|uniprotkb:Q9BZZ8|uniprotkb:Q9BZZ9|uniprotkb:Q9HAV8|uniprotkb:Q9UFT4|uniprotkb:Q9Y2E0|uniprotkb:E9PE50|uniprotkb:I6L9D9|uniprotkb:Q9H5Z7|uniprotkb:Q9H5Z8|ensembl:ENSP00000460475|ensembl:ENSP00000478516	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nlrp1_human(display_long)|uniprotkb:NLRP1(gene name)|psi-mi:NLRP1(display_short)|uniprotkb:CARD7(gene name synonym)|uniprotkb:DEFCAP(gene name synonym)|uniprotkb:KIAA0926(gene name synonym)|uniprotkb:NAC(gene name synonym)|uniprotkb:NALP1(gene name synonym)|uniprotkb:Death effector filament-forming ced-4-like apoptosis protein(gene name synonym)|uniprotkb:Nucleotide-binding domain and caspase recruitment domain(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001028225.1|refseq:NP_055737.1|refseq:NP_127497.1|refseq:NP_127499.1|refseq:NP_127500.1|dip:DIP-38407N|ensembl:ENSG00000091592(gene)|ensembl:ENST00000572272(transcript)|ensembl:ENST00000617618(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0006954"(inflammatory response)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070269"(pyroptosis)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0097264"(self proteolysis)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0140608"(cysteine-type endopeptidase activator activity)|go:"GO:1904784"(NLRP1 inflammasome complex assembly)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR004020(Pyrin)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|interpro:IPR027417|interpro:IPR032675|interpro:IPR033516|interpro:IPR041075|interpro:IPR041267|rcsb pdb:1PN5|rcsb pdb:3KAT|rcsb pdb:4IFP|rcsb pdb:4IM6|rcsb pdb:5Y3S|rcsb pdb:6K7V|rcsb pdb:6X6C|rcsb pdb:6XKK|reactome:R-HSA-844455	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tlXizUa/MP9AnLH5RpYPMcCB3UY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9C091	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721195|uniprotkb:A4QN17|uniprotkb:Q9H8F1|ensembl:ENSP00000412060|ensembl:ENSP00000464162	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:grb1l_human(display_long)|uniprotkb:Growth regulation by estrogen in breast cancer 1-like protein(gene name synonym)|uniprotkb:GREB1L(gene name)|psi-mi:GREB1L(display_short)|uniprotkb:C18orf6(gene name synonym)|uniprotkb:KIAA1772(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001136438.1|ensembl:ENSG00000141449(gene)|ensembl:ENST00000424526(transcript)|ensembl:ENST00000580732(transcript)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030539"(male genitalia development)|go:"GO:0060065"(uterus development)|go:"GO:0061205"(paramesonephric duct development)|go:"GO:0072177"(mesonephric duct development)|interpro:IPR024840|interpro:IPR028422	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:kaliF+A3EODqMvmBjmCySbtQXJ09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NRM1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11892601|uniprotkb:Q17RI5|uniprotkb:Q9H3D1|ensembl:ENSP00000379383	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:enam_human(display_long)|uniprotkb:ENAM(gene name)|psi-mi:ENAM(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_114095.2|refseq:XP_006714119.1|ensembl:ENSG00000132464(gene)|ensembl:ENST00000396073(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030345"(structural constituent of tooth enamel)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0036305"(ameloblast differentiation)|go:"GO:0070175"(positive regulation of enamel mineralization)|go:"GO:0097186"(amelogenesis)|interpro:IPR015673(Enamelin)|reactome:R-HSA-381426|reactome:R-HSA-8957275	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:til0BfEjGQ7KHVYfVpdZ5EP5Fw49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8NHW5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355416	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rla0l_human(display_long)|uniprotkb:RPLP0P6(gene name)|psi-mi:RPLP0P6(display_short)|uniprotkb:Large ribosomal subunit protein uL10-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR001790(Ribosomal protein L10)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR040637|interpro:IPR030670|interpro:IPR043141|interpro:IPR043164	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:mwr/+G18VKkJ2yrEjIMbz9m058o9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:A6NKL6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721181|ensembl:ENSP00000372982|ensembl:ENSP00000463375	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:t200c_human(display_long)|uniprotkb:Transmembrane protein TTMA(gene name synonym)|uniprotkb:Two transmembrane domain-containing family member A(gene name synonym)|uniprotkb:TMEM200C(gene name)|psi-mi:TMEM200C(display_short)|uniprotkb:TTMA(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000206432(gene)|ensembl:ENST00000383490(transcript)|ensembl:ENST00000581347(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018787|refseq:NP_001073678.1|refseq:XP_011524031.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:sa7Utd3cV+XhtMtMGhwRywqwa049606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P14543	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2828729|uniprotkb:Q86XD7|uniprotkb:Q5TAF3|uniprotkb:Q5TAF2|uniprotkb:Q14942|uniprotkb:Q59FL2|ensembl:ENSP00000264187	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nid1_human(display_long)|uniprotkb:NID1(gene name)|psi-mi:NID1(display_short)|uniprotkb:NID(gene name synonym)|uniprotkb:Entactin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002499.2|ensembl:ENSG00000116962(gene)|ensembl:ENST00000264187(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071711"(basement membrane organization)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036857|rcsb pdb:1NDX|reactome:R-HSA-1474228|reactome:R-HSA-3000157	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:xlqES3FTQirfYhb0lB7RfGpFQms9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q16880	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11337945|uniprotkb:O00196|uniprotkb:B3KXU7|ensembl:ENSP00000311648|ensembl:ENSP00000378019	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cgt_human(display_long)|uniprotkb:UGT8(gene name)|psi-mi:UGT8(display_short)|uniprotkb:CGT(gene name synonym)|uniprotkb:Ceramide UDP-galactosyltransferase(gene name synonym)|uniprotkb:Cerebroside synthase(gene name synonym)|uniprotkb:UDP-galactose-ceramide galactosyltransferase(gene name synonym)|uniprotkb:UGT4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001121646.1|refseq:NP_003351.2|refseq:NP_001309041.1|refseq:NP_001309042.1|refseq:NP_001309043.1|ensembl:ENSG00000174607(gene)|ensembl:ENST00000310836(transcript)|ensembl:ENST00000394511(transcript)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003851"(2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006682"(galactosylceramide biosynthetic process)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008489"("UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047263"(N-acylsphingosine galactosyltransferase activity)|go:"GO:0048812"(neuron projection morphogenesis)|interpro:IPR002213(UDP-glucuronosyl/UDP-glucosyltransferase)|interpro:IPR035595|mint:Q16880|reactome:R-HSA-1660662	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:y+KnxmigfB5YoTUKj1OVgAOougM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8NG08	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2857808|uniprotkb:Q4G0T2|uniprotkb:Q9H7L5|uniprotkb:A8K4C9|ensembl:ENSP00000247815|ensembl:ENSP00000443287	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:helb_human(display_long)|uniprotkb:HELB(gene name)|psi-mi:HELB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_387467.2|refseq:XP_005269291.1|ensembl:ENSG00000127311(gene)|ensembl:ENST00000247815(transcript)|ensembl:ENST00000545134(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR027044|interpro:IPR027417|interpro:IPR027785	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:raNaHGVcm41zMDqtYrqtYIDj1l49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q7Z407	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721154|ensembl:ENSP00000297405|uniprotkb:Q96PZ3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:csmd3_human(display_long)|uniprotkb:CUB and sushi multiple domains protein 3(gene name synonym)|uniprotkb:CSMD3(gene name)|psi-mi:CSMD3(display_short)|uniprotkb:KIAA1894(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000164796(gene)|ensembl:ENST00000297405(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050773"(regulation of dendrite development)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000859(CUB)|interpro:IPR035914|interpro:IPR035976|refseq:NP_443132.3|refseq:NP_937756.1|refseq:NP_937757.1|refseq:XP_016868498.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Fz4IiMCeNVLLDoNxee60Z3UGRpM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P50221	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q92696	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-9104196|uniprotkb:A8K5N2|uniprotkb:D3DS69|ensembl:ENSP00000216840|ensembl:ENSP00000382341|ensembl:ENSP00000494636|ensembl:ENSP00000496595	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pgta_human(display_long)|uniprotkb:RABGGTA(gene name)|psi-mi:RABGGTA(display_short)|uniprotkb:Geranylgeranyl transferase type II subunit alpha(gene name synonym)|uniprotkb:Rab geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:Rab geranylgeranyltransferase subunit alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004572.3|refseq:NP_878256.1|ensembl:ENSG00000100949(gene)|ensembl:ENSG00000285193(gene)|ensembl:ENST00000216840(transcript)|ensembl:ENST00000399409(transcript)|ensembl:ENST00000644383(transcript)|ensembl:ENST00000646658(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|interpro:IPR009087(Rab geranylgeranyltransferase, alpha subunit, insert)|interpro:IPR032675|interpro:IPR032955|interpro:IPR036254|reactome:R-HSA-6803205|reactome:R-HSA-8873719	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:oPWV+8Ppm2LhrEekspnRE/9YSK09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UKP5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721120|ensembl:ENSP00000370443|uniprotkb:Q59EX6|uniprotkb:Q5IR87|uniprotkb:Q5IR88|uniprotkb:Q5IR89|uniprotkb:Q68DL1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ats6_human(display_long)|uniprotkb:ADAMTS6(gene name)|psi-mi:ADAMTS6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000049192(gene)|ensembl:ENST00000381055(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0046872"(metal ion binding)|go:"GO:0060976"(coronary vasculature development)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR013273(Peptidase M12B, ADAM-TS)|interpro:IPR024079|interpro:IPR036383|interpro:IPR041645|reactome:R-HSA-5083635|reactome:R-HSA-5173214|refseq:NP_922932.2|refseq:XP_011541415.1|refseq:XP_011541416.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:PGSJuc2Wg+0+Ft0L5SN6398lwZA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75962	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-718519|uniprotkb:Q13458|uniprotkb:Q59EQ7|uniprotkb:Q6PJC9|uniprotkb:Q6ZN05|uniprotkb:Q8IWK8|uniprotkb:D3DTD1|ensembl:ENSP00000339299	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:trio_human(display_long)|uniprotkb:PTPRF-interacting protein(gene name synonym)|uniprotkb:TRIO(gene name)|psi-mi:TRIO(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_009049.2|refseq:XP_011512412.1|ensembl:ENSG00000038382(gene)|ensembl:ENST00000344204(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0042995"(cell projection)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036179|interpro:IPR036865|mint:O75962|rcsb pdb:1NTY|rcsb pdb:2NZ8|rcsb pdb:6D8Z|reactome:R-HSA-193648|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418885|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|interpro:IPR008271(Serine/threonine protein kinase, active site)|dip:DIP-37578N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:d01ioB7N6ccwAkeeoGpAa9GHZN89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75575	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2654687|uniprotkb:Q8IXL4|uniprotkb:Q3KRA3|uniprotkb:A8MW23|uniprotkb:B2R4H4|intact:EBI-2855843|uniprotkb:Q5HYF1|uniprotkb:B4E198|intact:EBI-28977752|ensembl:ENSP00000378736|uniprotkb:A8MUZ4	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rpc9_human(display_long)|uniprotkb:Calcitonin gene-related peptide-receptor component protein(gene name synonym)|uniprotkb:CRCP(gene name)|psi-mi:CRCP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001035738.1|ensembl:ENST00000338592|ensembl:ENSP00000340044|ensembl:ENSP00000378736|ensembl:ENST00000398684|ensembl:ENSP00000381674|ensembl:ENST00000431089|ensembl:ENSP00000388653|refseq:NP_001035737.1|refseq:NP_055293.1|refseq:NP_001135886.1|ensembl:ENSG00000241258(gene)|ensembl:ENST00000395326(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001635"(calcitonin gene-related peptide receptor activity)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|interpro:IPR038846|mint:O75575|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Xrb72g8eT2zV3NAFFyJXEBrloro9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O95714	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1058922|uniprotkb:Q86SV7|uniprotkb:Q86SV8|uniprotkb:Q86SV9|uniprotkb:Q86YY3|uniprotkb:Q86YY4|uniprotkb:Q86YY5|uniprotkb:Q86YY6|uniprotkb:Q86YY7|uniprotkb:Q86YY8|uniprotkb:Q86YY9|uniprotkb:Q86YZ0|uniprotkb:Q86YZ1|intact:EBI-1104961|intact:EBI-28977852|ensembl:ENSP00000261609	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:herc2_human(display_long)|uniprotkb:HERC2(gene name)|psi-mi:HERC2(display_short)|uniprotkb:HECT domain and RCC1-like domain-containing protein 2(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HERC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000261609|refseq:NP_004658.3|ensembl:ENSG00000128731(gene)|ensembl:ENST00000261609(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032183"(SUMO binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR000569(HECT)|interpro:IPR001199(Cytochrome b5)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR006624(Beta-propeller repeat TECPR)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR010606(Mib-herc2)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR021097|interpro:IPR035983|interpro:IPR036400|interpro:IPR037252|interpro:IPR037976|interpro:IPR041987|interpro:IPR043145|mint:O95714|rcsb pdb:2KEO|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:3KCI|rcsb pdb:4L1M|rcsb pdb:6WW4|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|reactome:R-HSA-983168|rcsb pdb:6WW3|dip:DIP-37632N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ejMTmb0F9pM7zfHbRscV1rIRgSw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5S007	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-5323863|ensembl:ENSP00000298910|uniprotkb:A6NJU2|uniprotkb:Q6ZS50|uniprotkb:Q8NCX9|intact:EBI-28978369	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lrrk2_human(display_long)|uniprotkb:LRRK2(gene name)|psi-mi:LRRK2(display_short)|uniprotkb:PARK8(gene name synonym)|uniprotkb:Dardarin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030276"(clathrin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|ensembl:ENSG00000188906(gene)|ensembl:ENST00000298910(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0015631"(tubulin binding)|go:"GO:0016234"(inclusion body)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0021756"(striatum development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034211"(GTP-dependent protein kinase activity)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036479"(peroxidase inhibitor activity)|go:"GO:0039706"(co-receptor binding)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0097487"(multivesicular body, internal vesicle)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099400"(caveola neck)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901727"(positive regulation of histone deacetylase activity)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0045121"(membrane raft)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0070997"(neuron death)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1903125"(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1903217"(negative regulation of protein processing involved in protein targeting to mitochondrion)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903980"(positive regulation of microglial cell activation)|go:"GO:1904713"(beta-catenin destruction complex binding)|go:"GO:1904887"(Wnt signalosome assembly)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020859|interpro:IPR025875|interpro:IPR027417|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR032171|interpro:IPR032675|interpro:IPR036322|interpro:IPR036770|mint:Q5S007|rcsb pdb:2ZEJ|rcsb pdb:3D6T|rcsb pdb:5MY9|rcsb pdb:5MYC|rcsb pdb:6DLO|rcsb pdb:6DLP|rcsb pdb:6OJE|rcsb pdb:6OJF|rcsb pdb:6VNO|rcsb pdb:6VP6|rcsb pdb:6VP7|rcsb pdb:6XAF|rcsb pdb:6XR4|rcsb pdb:7LHT|rcsb pdb:7LHW|rcsb pdb:7LI3|rcsb pdb:7LI4|reactome:R-HSA-8857538|ensembl:ENSP00000298910|refseq:NP_940980.3|dip:DIP-29684N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:5ZNs+6rMb4Ifz0nBk6RgYmaCFsM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P27816	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-715255|uniprotkb:Q59FT2|uniprotkb:Q68D74|uniprotkb:Q6ZUW9|uniprotkb:Q96NS9|uniprotkb:Q13082|uniprotkb:Q96A76|ensembl:ENSP00000353375|uniprotkb:Q86V26	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:map4_human(display_long)|uniprotkb:MAP4(gene name)|psi-mi:MAP4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001127836.1|refseq:NP_002366.2|ensembl:ENSG00000047849(gene)|ensembl:ENST00000360240(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27816|refseq:NP_112147.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rBf82W3kFCo+2UklK5WHO3MWjV09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96JN2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-947045|uniprotkb:A4D1K1|uniprotkb:Q6ZVK7|uniprotkb:Q9H8M3|uniprotkb:Q9UFE1|uniprotkb:A7MCY7|uniprotkb:A8MYA7|ensembl:ENSP00000297788	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cc136_human(display_long)|uniprotkb:NAG6(orf name)|uniprotkb:CCDC136(gene name)|psi-mi:CCDC136(display_short)|uniprotkb:KIAA1793(gene name synonym)|uniprotkb:Nasopharyngeal carcinoma-associated gene 6 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001188301.1|refseq:NP_073579.4|refseq:XP_016868022.1|ensembl:ENSG00000128596(gene)|ensembl:ENST00000297788(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016021"(integral component of membrane)|mint:Q96JN2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:TEC/bwvyX2dh9hhk8JmyVUWhSKo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N5M1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1166928|uniprotkb:A6NDE5|uniprotkb:A8K2J2|uniprotkb:Q6XYC7|ensembl:ENSP00000417190	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:atpf2_human(display_long)|uniprotkb:ATPAF2(gene name)|psi-mi:ATPAF2(display_short)|uniprotkb:ATP12(gene name synonym)|uniprotkb:LP3663(orf name)|uniprotkb:ATP12 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_663729.1|ensembl:ENSG00000171953(gene)|ensembl:ENST00000474627(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043461"(proton-transporting ATP synthase complex assembly)|interpro:IPR011419(ATP12 ATPase)|interpro:IPR023335|interpro:IPR042272	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ifcwz4YWJr0UVp2WbqJmiqrhI809606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86US8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-3232100|ensembl:ENSP00000263073|uniprotkb:O94837|uniprotkb:Q9UF60|uniprotkb:Q86VH6|uniprotkb:B7Z874	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:est1a_human(display_long)|uniprotkb:SMG6(gene name)|psi-mi:SMG6(display_short)|uniprotkb:C17orf31(gene name synonym)|uniprotkb:EST1A(gene name synonym)|uniprotkb:KIAA0732(gene name synonym)|uniprotkb:EST1-like protein A(gene name synonym)|uniprotkb:Ever shorter telomeres 1A(gene name synonym)|uniprotkb:Smg-6 homolog(gene name synonym)|uniprotkb:Telomerase subunit EST1A(gene name synonym)|uniprotkb:hSmg5/7a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENST00000263073(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|interpro:IPR029060|mint:Q86US8|rcsb pdb:2DOK|rcsb pdb:2HWW|rcsb pdb:2HWX|rcsb pdb:4UM2|reactome:R-HSA-975957|ensembl:ENSG00000070366(gene)|refseq:XP_011522071.1|refseq:XP_011522077.1|refseq:NP_060045.4|refseq:NP_001243756.1|refseq:NP_001243757.1|refseq:NP_001269255.1|refseq:XP_005256626.1|refseq:XP_005256628.1|refseq:XP_016879888.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:UoAA9ikMFv3EHZZozUAOkWWPrRM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86YC2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BS34	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-745276|intact:EBI-28980552|ensembl:ENSP00000355459	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:zn670_human(display_long)|uniprotkb:ZNF670(gene name)|psi-mi:ZNF670(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_149990.1|ensembl:ENSP00000355459|ensembl:ENSG00000277462(gene)|ensembl:ENST00000366503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q9BS34|reactome:R-HSA-212436	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rLN4zdWhS14BhRLxojEevuc2Knc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9ULQ0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IZH2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-372406|uniprotkb:Q4G0S3|uniprotkb:Q68D88|uniprotkb:Q6AI24|uniprotkb:Q6MZS8|uniprotkb:Q86WS7|uniprotkb:Q8N8U4|uniprotkb:Q9UF39|ensembl:ENSP00000264951	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:xrn1_human(display_long)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_061874.3|refseq:NP_001269786.1|refseq:NP_001269788.1|ensembl:ENSG00000114127(gene)|ensembl:ENST00000264951(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0033574"(response to testosterone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1905795"(cellular response to puromycin)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR016494(5'-3' exoribonuclease 1)|interpro:IPR027073|interpro:IPR040992|interpro:IPR041106|interpro:IPR041385|interpro:IPR041412|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|dip:DIP-31174N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Y5wskamFEhJ+vmrGjlw4nYHiWLg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y566	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-3442234|uniprotkb:B7WNY6|uniprotkb:Q9NYW9|uniprotkb:A8MXP5|ensembl:ENSP00000293441	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:shan1_human(display_long)|uniprotkb:SHANK1(gene name)|psi-mi:SHANK1(display_short)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011525316.1|refseq:XP_006723296.1|refseq:NP_057232.2|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|ensembl:ENSG00000161681(gene)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|ensembl:ENST00000293441(transcript)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9Y566|rcsb pdb:6CPI|rcsb pdb:6YWZ|rcsb pdb:6YX0|rcsb pdb:6YX1|rcsb pdb:6YX2|reactome:R-HSA-6794361|ensembl:ENSP00000293441|ensembl:ENST00000359082|ensembl:ENSP00000351984|dip:DIP-40834N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:XhX+mw+sujJRnA6RoKA1QeVywBY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IZ81	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2870624|uniprotkb:B2R712|uniprotkb:D3DNZ0|ensembl:ENSP00000326342	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:elmd2_human(display_long)|uniprotkb:ELMOD2(gene name)|psi-mi:ELMOD2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011530121.1|refseq:NP_714913.1|refseq:XP_005262943.1|ensembl:ENSG00000179387(gene)|ensembl:ENST00000323570(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR030724	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:iHZqyHuBsrKkkW4IcIiw3zg06pk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9ULL5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2803349|uniprotkb:E9PB06|uniprotkb:Q8N4J6|intact:EBI-28976287|ensembl:ENSP00000394510	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:prr12_human(display_long)|uniprotkb:KIAA1205(gene name synonym)|uniprotkb:PRR12(gene name)|psi-mi:PRR12(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000394510|refseq:NP_065770.1|ensembl:ENSG00000126464(gene)|ensembl:ENST00000418929(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043005"(neuron projection)|interpro:IPR025451	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wWq0/S4FG/9wrPyvqU9CyvIQSA09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96EM0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721107|ensembl:ENSP00000247194|uniprotkb:Q96LJ5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:t3hpd_human(display_long)|uniprotkb:Trans-L-3-hydroxyproline dehydratase(gene name synonym)|uniprotkb:L3HYPDH(gene name)|psi-mi:L3HYPDH(display_short)|uniprotkb:C14orf149(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000126790(gene)|ensembl:ENST00000247194(transcript)|go:"GO:0016836"(hydro-lyase activity)|go:"GO:0050346"(trans-L-3-hydroxyproline dehydratase activity)|interpro:IPR008794(Proline racemase)|refseq:NP_653182.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:XiP5PSB2POewYm2YscHXbciz3d49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y6E2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1051021|uniprotkb:Q3B779|uniprotkb:Q9H3F7|uniprotkb:A4D123|uniprotkb:Q96JW5|ensembl:ENSP00000258761|ensembl:ENSP00000397249	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:bzw2_human(display_long)|uniprotkb:BZW2(gene name)|psi-mi:BZW2(display_short)|uniprotkb:HSPC028(orf name)|uniprotkb:MSTP017(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001153239.1|refseq:NP_054757.1|ensembl:ENSG00000136261(gene)|ensembl:ENST00000258761(transcript)|ensembl:ENST00000433922(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|refseq:XP_006715769.1|refseq:XP_006715770.1|refseq:XP_006715771.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:+z22Ykb6e3IM9zk51m6tjuhiEcU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6V0I7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-948985|intact:EBI-28972157|uniprotkb:A8K5Z6|uniprotkb:Q3LIA6|uniprotkb:Q8TCK7|uniprotkb:Q9H5T6|uniprotkb:B5MDG4	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:fat4_human(display_long)|uniprotkb:CDHF14(gene name synonym)|uniprotkb:FATJ(gene name synonym)|uniprotkb:FAT tumor suppressor homolog 4(gene name synonym)|uniprotkb:Fat-like cadherin protein FAT-J(gene name synonym)|uniprotkb:Nbla00548(orf name)|uniprotkb:FAT4(gene name)|psi-mi:FAT4(display_short)|uniprotkb:Cadherin family member 14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001278214.1|refseq:NP_001278232.1|ensembl:ENST00000335110|ensembl:ENSP00000335169|ensembl:ENSG00000196159|interpro:IPR009030(Growth factor, receptor)|refseq:NP_078858.4|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|interpro:IPR001791(Laminin G)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0035329"(hippo signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:JEQAZjR7zgJIqxYmiN/iLmijNbE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NQW8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721082|ensembl:ENSP00000316605|uniprotkb:C9JA51|uniprotkb:Q9NRE9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cngb3_human(display_long)|uniprotkb:Cone photoreceptor cGMP-gated channel subunit beta(gene name synonym)|uniprotkb:Cyclic nucleotide-gated cation channel modulatory subunit(gene name synonym)|uniprotkb:Cyclic nucleotide-gated channel beta-3(gene name synonym)|uniprotkb:CNGB3(gene name)|psi-mi:CNGB3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000170289(gene)|ensembl:ENST00000320005(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005222"(intracellular cAMP-activated cation channel activity)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0006812"(cation transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0030553"(cGMP binding)|go:"GO:1902495"(transmembrane transporter complex)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR032943|refseq:NP_061971.3	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:kChst/Fe80sEw84cmA09CPrb1j89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13523	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y6X0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2548259|intact:EBI-28969274|ensembl:ENSP00000497406|ensembl:ENSP00000502995|ensembl:ENSP00000503094|ensembl:ENSP00000503656|ensembl:ENSP00000504398|uniprotkb:A6H8W5|uniprotkb:Q9UEF3|uniprotkb:Q6P6C3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:setbp_human(display_long)|uniprotkb:SETBP1(gene name)|psi-mi:SETBP1(display_short)|uniprotkb:KIAA0437(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000152217(gene)|ensembl:ENST00000649279(transcript)|ensembl:ENST00000677068(transcript)|ensembl:ENST00000677077(transcript)|ensembl:ENST00000677130(transcript)|ensembl:ENST00000678152(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR017956|ensembl:ENST00000426838|ensembl:ENSP00000390687|ensembl:ENSP00000497406|ensembl:ENSP00000504398|ensembl:ENSP00000503656|ensembl:ENSP00000503094|ensembl:ENSP00000502995|refseq:NP_001123582.1|refseq:NP_056374.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:bPLw8rppZYzLANH100jgHI5yfhI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O95639	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-725860|uniprotkb:Q86TF8|uniprotkb:Q9BTW6|uniprotkb:Q6FGE6|uniprotkb:D6W5S8|ensembl:ENSP00000292476	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cpsf4_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 30 kDa subunit(gene name synonym)|uniprotkb:NS1 effector domain-binding protein 1(gene name synonym)|uniprotkb:No arches homolog(gene name synonym)|uniprotkb:CPSF4(gene name)|psi-mi:CPSF4(display_short)|uniprotkb:CPSF30(gene name synonym)|uniprotkb:NAR(gene name synonym)|uniprotkb:NEB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001075028.1|refseq:NP_006684.1|refseq:NP_001305089.1|refseq:NP_001305090.1|refseq:NP_001305091.1|ensembl:ENSG00000160917(gene)|ensembl:ENST00000292476(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036855|interpro:IPR036875|interpro:IPR041686|mint:O95639|rcsb pdb:2D9N|rcsb pdb:2RHK|rcsb pdb:6DNH|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-168315|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-48675N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:CTNuFmbdKiPNvBJPEHoLi7WvoYM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5T5P2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-746898|uniprotkb:A5LHW9|uniprotkb:A6PVQ5|uniprotkb:A6PVQ6|uniprotkb:A6PVQ7|uniprotkb:Q5T5P3|uniprotkb:Q4KMG4|uniprotkb:Q5T7H3|uniprotkb:Q6MZZ6|uniprotkb:Q6ZUI4|uniprotkb:Q8WV45|uniprotkb:Q9NSR2|uniprotkb:Q9ULK3|ensembl:ENSP00000365637|uniprotkb:A6NLF3|uniprotkb:B9EGK4	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:skt_human(display_long)|uniprotkb:KIAA1217(gene name)|psi-mi:KIAA1217(display_short)|uniprotkb:SKT(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001091970.1|refseq:NP_001269696.1|refseq:NP_001269697.1|refseq:NP_001269698.1|refseq:NP_001269699.1|refseq:NP_062536.2|refseq:XP_016871918.1|ensembl:ENSG00000120549(gene)|ensembl:ENST00000376454(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR022782|interpro:IPR026725|refseq:XP_005252573.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3rlNZUWLC4c0hvktiGEo55Sj15Q9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P2P6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-718809|uniprotkb:Q9UF70|uniprotkb:Q68DG2|uniprotkb:Q6AI01|uniprotkb:Q6ZWK0|ensembl:ENSP00000290607	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:star9_human(display_long)|uniprotkb:START domain-containing protein 9(gene name synonym)|uniprotkb:STARD9(gene name)|psi-mi:STARD9(display_short)|uniprotkb:KIAA1300(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_065810.2|ensembl:ENSP00000290607|ensembl:ENSG00000159433(gene)|ensembl:ENST00000290607(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0051225"(spindle assembly)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR023393|interpro:IPR027417|interpro:IPR036961|interpro:IPR042990	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:N7cUxVyUPfN8YNsMYXpb66WI/Sg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q03001	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P227	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721052|ensembl:ENSP00000479208|ensembl:ENSP00000481862	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rhg23_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 23(gene name synonym)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000273780(gene)|ensembl:ENSG00000275832(gene)|ensembl:ENST00000610551(transcript)|ensembl:ENST00000622683(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000198(RhoGAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR041489|interpro:IPR041681|reactome:R-HSA-8980692|reactome:R-HSA-9013149|refseq:NP_001186346.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P43363	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11081653|intact:EBI-28989111|ensembl:ENSP00000244096|ensembl:ENSP00000359347	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:magaa_human(display_long)|uniprotkb:MAGEA10(gene name)|psi-mi:MAGEA10(display_short)|uniprotkb:Cancer/testis antigen 1.10(gene name synonym)|uniprotkb:MAGE-10 antigen(gene name synonym)|uniprotkb:MAGE10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001011543.2|refseq:NP_001238757.1|refseq:NP_066386.2|ensembl:ENSP00000244096|ensembl:ENSP00000359347|ensembl:ENSG00000124260(gene)|ensembl:ENST00000244096(transcript)|ensembl:ENST00000370323(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030102|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|go:"GO:0005829"(cytosol)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:fEf315RjnCl6VBc2u+IvPz7RK8c9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NYQ7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-308417|uniprotkb:O75092|ensembl:ENSP00000164024	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:celr3_human(display_long)|uniprotkb:CELSR3(gene name)|psi-mi:CELSR3(display_short)|uniprotkb:CDHF11(gene name synonym)|uniprotkb:EGFL1(gene name synonym)|uniprotkb:FMI1(gene name synonym)|uniprotkb:KIAA0812(gene name synonym)|uniprotkb:MEGF2(gene name synonym)|uniprotkb:Flamingo homolog 1(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 1(gene name synonym)|uniprotkb:Multiple epidermal growth factor-like domains protein 2(gene name synonym)|uniprotkb:Cadherin family member 11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001398.2|ensembl:ENSP00000164024|ensembl:ENSG00000008300(gene)|ensembl:ENST00000164024(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000203(GPS)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001791(Laminin G)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR017981|interpro:IPR017983|interpro:IPR020894|interpro:IPR032471|interpro:IPR036445	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:qei5dGZ3Ax997Bc6TQjwui1692s9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P49588	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-709710|uniprotkb:A6NF14|uniprotkb:Q53GV7|uniprotkb:Q96FA0|uniprotkb:B4DR45|ensembl:ENSP00000261772|ensembl:ENSP00000501924|ensembl:ENSP00000502247|ensembl:ENSP00000502797	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:syac_human(display_long)|uniprotkb:AARS1(gene name)|psi-mi:AARS1(display_short)|uniprotkb:AARS(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-42(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001596.2|ensembl:ENSG00000090861(gene)|ensembl:ENST00000261772(transcript)|ensembl:ENST00000674691(transcript)|ensembl:ENST00000674963(transcript)|ensembl:ENST00000675643(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0002196"("Ser-tRNA(Ala) hydrolase activity")|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016597"(amino acid binding)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140018"(regulation of cytoplasmic translational fidelity)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:P49588|rcsb pdb:4XEM|rcsb pdb:4XEO|rcsb pdb:5KNN|rcsb pdb:5T5S|rcsb pdb:5T76|rcsb pdb:5V59|reactome:R-HSA-379716	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:e9+gLroLXvK8li0wiPBGbZhQqP49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O60296	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2851680|uniprotkb:Q9C0K6|uniprotkb:Q8WVH7|uniprotkb:Q96NS2|uniprotkb:Q9C0K5|uniprotkb:E7EV21|ensembl:ENSP00000328875	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:trak2_human(display_long)|uniprotkb:TRAK2(gene name)|psi-mi:TRAK2(display_short)|uniprotkb:ALS2CR3(gene name synonym)|uniprotkb:KIAA0549(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011509992.1|ensembl:ENSP00000328875|ensembl:ENST00000430254|ensembl:ENSP00000409333|refseq:NP_055864.2|ensembl:ENSG00000115993(gene)|ensembl:ENST00000332624(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098972"(anterograde dendritic transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|reactome:R-HSA-9013419|reactome:R-HSA-9013425	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:aBkA/J62vwLCHbYqkaXOE4rbaZ89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96G03	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-4399372|uniprotkb:Q53FP5|uniprotkb:Q5QTR0|uniprotkb:Q9H0P9|uniprotkb:Q9NV22|uniprotkb:B4E0G8|ensembl:ENSP00000371393	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pgm2_human(display_long)|uniprotkb:PGM2(gene name)|psi-mi:PGM2(display_short)|uniprotkb:Glucose phosphomutase 2(gene name synonym)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:Phosphopentomutase(gene name synonym)|uniprotkb:MSTP006(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_060760.2|ensembl:ENSG00000169299(gene)|ensembl:ENST00000381967(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0008973"(phosphopentomutase activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0046386"(deoxyribose phosphate catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900|reactome:R-HSA-3322077|reactome:R-HSA-6798695|reactome:R-HSA-70221|reactome:R-HSA-70370|reactome:R-HSA-71336	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:N3OyLlxMboSlj1tiY+lCqBo6QKE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NWS1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721015|ensembl:ENSP00000332915|uniprotkb:B4E0Y0|uniprotkb:Q05C00|uniprotkb:Q499L8|uniprotkb:Q4FZA0|uniprotkb:Q4KMW7|uniprotkb:Q6NSC6|uniprotkb:Q6PJA1|uniprotkb:Q86W36	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pari_human(display_long)|uniprotkb:PARP-1 binding protein(gene name synonym)|uniprotkb:PARP1-binding protein(gene name synonym)|uniprotkb:PARPBP(gene name)|psi-mi:PARPBP(display_short)|uniprotkb:C12orf48(gene name synonym)|uniprotkb:PARI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000185480(gene)|ensembl:ENST00000327680(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR027417|interpro:IPR038932|mint:Q9NWS1|refseq:NP_001306917.1|refseq:NP_001306922.1|refseq:NP_001306923.1|refseq:NP_001306924.1|refseq:NP_001306925.1|refseq:NP_060385.3|refseq:XP_016875032.1|refseq:XP_016875033.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:xTVAb2XN75GQqL8tvj/3gTbRd2M9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P43007	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11343290|uniprotkb:D6W5F0|uniprotkb:B7Z3C0|intact:EBI-28986983|ensembl:ENSP00000234256	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:satt_human(display_long)|uniprotkb:SLC1A4(gene name)|psi-mi:SLC1A4(display_short)|uniprotkb:ASCT1(gene name synonym)|uniprotkb:Alanine/serine/cysteine/threonine transporter 1(gene name synonym)|uniprotkb:SATT(gene name synonym)|uniprotkb:Solute carrier family 1 member 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001180422.1|refseq:NP_003029.2|ensembl:ENSP00000234256|ensembl:ENST00000531327|ensembl:ENSP00000431942|ensembl:ENSG00000115902(gene)|ensembl:ENST00000234256(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005813"(centrosome)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009986"(cell surface)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015184"(L-cystine transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015195"(L-threonine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015808"(L-alanine transport)|go:"GO:0015811"(L-cystine transport)|go:"GO:0015824"(proline transport)|go:"GO:0015825"(L-serine transport)|go:"GO:0015826"(threonine transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034589"(hydroxyproline transport)|go:"GO:0034590"(L-hydroxyproline transmembrane transporter activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903812"(L-serine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|reactome:R-HSA-352230	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:clBTMRJ8pRPFo1aWCnDSaTOe30E9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q7Z4L5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2851301|uniprotkb:Q53T84|uniprotkb:Q6PIF5|uniprotkb:A8MUZ3|uniprotkb:Q8NCN3|uniprotkb:Q9HAK8|uniprotkb:Q96MA4|uniprotkb:Q6P4A1|uniprotkb:Q3LIE4|ensembl:ENSP00000243344|ensembl:ENSP00000506276|ensembl:ENSP00000506400	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tt21b_human(display_long)|uniprotkb:TTC21B(gene name)|psi-mi:TTC21B(display_short)|uniprotkb:KIAA1992(gene name synonym)|uniprotkb:Nbla10696(orf name)|uniprotkb:IFT139(gene name synonym)|uniprotkb:Intraflagellar transport 139 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_079029.3|ensembl:ENSG00000123607(gene)|ensembl:ENST00000243344(transcript)|ensembl:ENST00000680888(transcript)|ensembl:ENST00000681952(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021591"(ventricular system development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0030991"(intraciliary transport particle A)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|go:"GO:0097542"(ciliary tip)|go:"GO:1903999"(negative regulation of eating behavior)|go:"GO:1905799"(regulation of intraciliary retrograde transport)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040364|reactome:R-HSA-5610787|reactome:R-HSA-5620924	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:y1VB2y4oBho3fxf1gOl0LAz2u8o9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IWA4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1048197|uniprotkb:D3DNR6|uniprotkb:O60639|uniprotkb:Q9BZB5|uniprotkb:Q9NWQ2|uniprotkb:O15323|uniprotkb:B2RAR1|ensembl:ENSP00000263969|ensembl:ENSP00000420617|uniprotkb:A0A0C4DFN1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mfn1_human(display_long)|uniprotkb:Transmembrane GTPase MFN1(gene name synonym)|uniprotkb:Fzo homolog(gene name synonym)|uniprotkb:MFN1(gene name)|psi-mi:MFN1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_284941.2|ensembl:ENSG00000171109(gene)|ensembl:ENST00000263969(transcript)|ensembl:ENST00000471841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031306"(intrinsic component of mitochondrial outer membrane)|interpro:IPR027088|interpro:IPR027094|interpro:IPR027417|interpro:IPR030381|rcsb pdb:5GNR|rcsb pdb:5GNS|rcsb pdb:5GNT|rcsb pdb:5GNU|rcsb pdb:5GO4|rcsb pdb:5GOE|rcsb pdb:5GOF|rcsb pdb:5GOM|rcsb pdb:5YEW|reactome:R-HSA-5205685|reactome:R-HSA-9013419|reactome:R-HSA-983231|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0098799"(outer mitochondrial membrane protein complex)|go:"GO:1990613"(mitochondrial membrane fusion)|interpro:IPR006884(Fzo-like conserved region)|interpro:IPR022812|refseq:XP_005247653.2|dip:DIP-50289N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:JqGBpXDIjWiNwJCt2/DOzE7wFxM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6Q759	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6152750|ensembl:ENSP00000337804|uniprotkb:Q9NT21|uniprotkb:Q8NAZ1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:spg17_human(display_long)|uniprotkb:Projection protein PF6 homolog(gene name synonym)|uniprotkb:SPAG17(gene name)|psi-mi:SPAG17(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000155761(gene)|ensembl:ENST00000336338(transcript)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005874"(microtubule)|go:"GO:0031514"(motile cilium)|go:"GO:1904158"(axonemal central apparatus assembly)|go:"GO:1990716"(axonemal central apparatus)|interpro:IPR026173|refseq:NP_996879.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:MFSwSmkAnM2sDnTLd8fes2VcGt09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96RT8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2555061|uniprotkb:Q96PY8|uniprotkb:Q6IQ52|ensembl:ENSP00000480316|uniprotkb:E9PB12	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:gcp5_human(display_long)|uniprotkb:GCP5(gene name synonym)|uniprotkb:KIAA1899(gene name synonym)|uniprotkb:TUBGCP5(gene name)|psi-mi:TUBGCP5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001096080.1|refseq:NP_443135.3|ensembl:ENSG00000275835(gene)|ensembl:ENST00000615383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008017"(microtubule binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|rcsb pdb:6L81|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|ensembl:ENSP00000480316|ensembl:ENST00000620435|ensembl:ENSP00000481853	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ERVu5LLd+VS+yKJoEk2tjh7z+n89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BQN1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1220251|uniprotkb:Q14D67|uniprotkb:Q5JWN6|uniprotkb:Q8N276|ensembl:ENSP00000363529	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:fa83c_human(display_long)|uniprotkb:FAM83C(gene name)|psi-mi:FAM83C(display_short)|uniprotkb:C20orf128(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_848563.1|ensembl:ENSG00000125998(gene)|ensembl:ENST00000374408(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|interpro:IPR012461(Protein of unknown function DUF1669)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:llvrYXDd2cTnSULf+NC+VtmOdgQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O95180	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6381173|intact:EBI-28983714|ensembl:ENSP00000334198|uniprotkb:B5ME00|uniprotkb:F8WFD1|uniprotkb:O95802|uniprotkb:Q8WWI6|uniprotkb:Q96QI6|uniprotkb:Q96RZ9|uniprotkb:Q9NYY4|uniprotkb:Q9NYY5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cac1h_human(display_long)|uniprotkb:CACNA1H(gene name)|psi-mi:CACNA1H(display_short)|uniprotkb:Low-voltage-activated calcium channel alpha1 3.2 subunit(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000196557(gene)|ensembl:ENST00000348261(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008332"(low voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0032342"(aldosterone biosynthetic process)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0034651"(cortisol biosynthetic process)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098662"(inorganic cation transmembrane transport)|go:"GO:2000344"(positive regulation of acrosome reaction)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359|mint:O95180|reactome:R-HSA-419037|ensembl:ENSP00000334198|ensembl:ENST00000358590|ensembl:ENSP00000351401|ensembl:ENST00000565831|ensembl:ENSP00000455840|refseq:NP_001005407.1|refseq:NP_066921.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wDz13CscEv3Kv2CYIF8r5sq0Ygc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P16112	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-9076211|uniprotkb:Q13650|uniprotkb:Q9UCD3|uniprotkb:Q9UCP4|uniprotkb:Q9UCP5|uniprotkb:Q9UDE0|uniprotkb:B9EK55|uniprotkb:E7ENV9|uniprotkb:E7EX88|uniprotkb:H0YM81|ensembl:ENSP00000387356	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pgca_human(display_long)|uniprotkb:ACAN(gene name)|psi-mi:ACAN(display_short)|uniprotkb:AGC1(gene name synonym)|uniprotkb:CSPG1(gene name synonym)|uniprotkb:MSK16(gene name synonym)|uniprotkb:Cartilage-specific proteoglycan core protein(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan core protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001126.3|refseq:NP_037359.3|refseq:XP_011519616.1|ensembl:ENSG00000157766(gene)|ensembl:ENST00000439576(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006508"(proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000538(Link)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001304(C-type lectin)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033987|interpro:IPR035976|interpro:IPR036179|rcsb pdb:4MD4|reactome:R-HSA-1474228|reactome:R-HSA-2022854|reactome:R-HSA-2022857|reactome:R-HSA-3000178|reactome:R-HSA-3656225|reactome:R-HSA-3656243|reactome:R-HSA-3656244	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:LZ89ZDUWHqLtFYDp4dNgMtm6fd09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P1Y5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-727407|uniprotkb:Q8NDF1|ensembl:ENSP00000160298	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:camp3_human(display_long)|uniprotkb:CAMSAP3(gene name)|psi-mi:CAMSAP3(display_short)|uniprotkb:KIAA1543(gene name synonym)|uniprotkb:Protein Nezha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000160298|ensembl:ENSP00000416797|ensembl:ENST00000446248|refseq:NP_001073898.1|refseq:NP_065953.1|dip:DIP-52405N|ensembl:ENSG00000076826(gene)|ensembl:ENST00000160298(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003341"(cilium movement)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005915"(zonula adherens)|go:"GO:0005930"(axoneme)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030507"(spectrin binding)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031514"(motile cilium)|go:"GO:0033043"(regulation of organelle organization)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:G/MLMkIhEdjbAiwPu+xvqJFgvPg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96J84	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-3988456|ensembl:ENSP00000352138|uniprotkb:Q5W0F8|uniprotkb:Q5XKC6|uniprotkb:Q7Z696|uniprotkb:Q7Z7N8|uniprotkb:Q8TB15|uniprotkb:Q9H9N1|uniprotkb:Q9NVA5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:kirr1_human(display_long)|uniprotkb:KIRREL1(gene name)|psi-mi:KIRREL1(display_short)|uniprotkb:KIRREL(gene name synonym)|uniprotkb:Kin of irregular chiasm-like protein 1(gene name synonym)|uniprotkb:NEPH1(gene name synonym)|uniprotkb:Nephrin-like protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001273278.1|ensembl:ENSG00000183853(gene)|ensembl:ENST00000359209(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0017022"(myosin binding)|go:"GO:0031253"(cell projection membrane)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|refseq:NP_060710.3|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-373753|go:"GO:0098609"(cell-cell adhesion)|refseq:XP_005245362.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:AZjf1PpCzbkuNJngJUPYa7bWYAo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P253	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P28749	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UL01	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-3917126|uniprotkb:Q5R3K6|ensembl:ENSP00000332151|ensembl:ENSP00000404049|ensembl:ENSP00000494147	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dse_human(display_long)|uniprotkb:DSE(gene name)|psi-mi:DSE(display_short)|uniprotkb:SART2(gene name synonym)|uniprotkb:Chondroitin-glucuronate 5-epimerase(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001309872.1|refseq:NP_001309873.1|refseq:NP_001309866.1|refseq:NP_001309867.1|refseq:NP_001309868.1|refseq:NP_001309869.1|refseq:NP_001309870.1|refseq:NP_001074445.1|refseq:NP_037484.1|ensembl:ENSG00000111817(gene)|ensembl:ENST00000331677(transcript)|ensembl:ENST00000452085(transcript)|ensembl:ENST00000644252(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030204"(chondroitin sulfate metabolic process)|go:"GO:0030205"(dermatan sulfate metabolic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0030208"(dermatan sulfate biosynthetic process)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0047757"(chondroitin-glucuronate 5-epimerase activity)|interpro:IPR008929(Chondroitin AC/alginate lyase)|interpro:IPR032518|rcsb pdb:6HZN|reactome:R-HSA-2022923|go:"GO:0000139"(Golgi membrane)|refseq:XP_016866285.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:n8rB9FlcH89+dZZJUcz6bT7fngk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y5X9	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-372509|uniprotkb:Q6P9C8|uniprotkb:Q6UW82|uniprotkb:B0LPG6|ensembl:ENSP00000261292	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lipe_human(display_long)|uniprotkb:Phospholipase A1(gene name synonym)|uniprotkb:UNQ387/PRO719(orf name)|uniprotkb:Endothelial cell-derived lipase(gene name synonym)|uniprotkb:LIPG(gene name)|psi-mi:LIPG(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001294935.1|refseq:NP_006024.1|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008201"(heparin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010983"(positive regulation of high-density lipoprotein particle clearance)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016298"(lipase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0050746"(regulation of lipoprotein metabolic process)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0055091"(phospholipid homeostasis)|interpro:IPR000734(Lipase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR002330(Lipoprotein lipase)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|reactome:R-HSA-8964058|ensembl:ENSG00000101670(gene)|ensembl:ENST00000261292(transcript)|go:"GO:0004465"(lipoprotein lipase activity)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:99+JsUIVVhXjBxBSKMkpPcAHUBg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P39748	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-707816|ensembl:ENSP00000305480	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:fen1_human(display_long)|uniprotkb:Flap structure-specific endonuclease 1(gene name synonym)|uniprotkb:Maturation factor 1(gene name synonym)|uniprotkb:DNase IV(gene name synonym)|uniprotkb:FEN1(gene name)|psi-mi:FEN1(display_short)|uniprotkb:RAD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000168496(gene)|ensembl:ENST00000305885(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|refseq:NP_004102.1|dip:DIP-24216N|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007613"(memory)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0009650"(UV protection)|go:"GO:0016020"(membrane)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR023426|interpro:IPR029060|interpro:IPR036279|mint:P39748|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:3Q8K|rcsb pdb:3Q8L|rcsb pdb:3Q8M|rcsb pdb:3UVU|rcsb pdb:5E0V|rcsb pdb:5FV7|rcsb pdb:5K97|rcsb pdb:5KSE|rcsb pdb:5UM9|rcsb pdb:5ZOD|rcsb pdb:5ZOE|rcsb pdb:5ZOF|rcsb pdb:5ZOG|rcsb pdb:6TNZ|reactome:R-HSA-110362|reactome:R-HSA-162594|reactome:R-HSA-174437|reactome:R-HSA-5651801|reactome:R-HSA-5685939|reactome:R-HSA-69166	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:l9A+/Q39cGBPac0d8USNWE+17NM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O95972	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-12594867|ensembl:ENSP00000252677|uniprotkb:Q17RM6|uniprotkb:Q5JST1|uniprotkb:Q9UMS1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:bmp15_human(display_long)|uniprotkb:BMP15(gene name)|psi-mi:BMP15(display_short)|uniprotkb:GDF9B(gene name synonym)|uniprotkb:Growth/differentiation factor 9B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000130385(gene)|ensembl:ENST00000252677(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007292"(female gamete generation)|go:"GO:0008083"(growth factor activity)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060016"(granulosa cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070698"(type I activin receptor binding)|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR015923(Bone morphogenetic protein 15)|interpro:IPR017948|interpro:IPR029034|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_005439.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:La2Oyr6HZVnWtKX1d68mxA5Q0v09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9H7D0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q99704	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1384360|uniprotkb:O43204|uniprotkb:Q53TY2|uniprotkb:Q9UHG6|ensembl:ENSP00000233668	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dok1_human(display_long)|uniprotkb:Downstream of tyrosine kinase 1(gene name synonym)|uniprotkb:"p62(dok)"(gene name synonym)|uniprotkb:pp62(gene name synonym)|uniprotkb:DOK1(gene name)|psi-mi:DOK1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001184189.1|refseq:NP_001372.1|refseq:NP_001305797.1|ensembl:ENSG00000115325(gene)|ensembl:ENST00000233668(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0038145"(macrophage colony-stimulating factor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037751|mint:Q99704|rcsb pdb:2V76|reactome:R-HSA-8849469|reactome:R-HSA-8853659	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Pvjez+wIa3gWdY9ZYvWN6lmOM4o9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86UK0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-9541582|uniprotkb:Q53QE2|uniprotkb:Q53S55|uniprotkb:Q8IZW6|uniprotkb:Q96JT3|uniprotkb:Q9Y4M5|ensembl:ENSP00000272895	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:abcac_human(display_long)|uniprotkb:ABCA12(gene name)|psi-mi:ABCA12(display_short)|uniprotkb:ABC12(gene name synonym)|uniprotkb:ATP-binding cassette transporter 12(gene name synonym)|uniprotkb:ATP-binding cassette sub-family A member 12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_056472.2|refseq:NP_775099.2|ensembl:ENSG00000144452(gene)|ensembl:ENST00000272895(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003336"(corneocyte desquamation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031424"(keratinization)|go:"GO:0032379"(positive regulation of intracellular lipid transport)|go:"GO:0032940"(secretion by cell)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034040"(ATPase-coupled lipid transmembrane transporter activity)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0035627"(ceramide transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0048286"(lung alveolus development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097209"(epidermal lamellar body)|go:"GO:0097234"(epidermal lamellar body membrane)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR026082|interpro:IPR027417|interpro:IPR030371|reactome:R-HSA-1369062|reactome:R-HSA-5682294	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:HZsVBkhHniBgQCaQVvqwlOk18+89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P16234	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2861522|uniprotkb:Q96KZ7|uniprotkb:B2RE69|uniprotkb:Q9UD28|uniprotkb:E9PBH0|uniprotkb:Q6P4H5|ensembl:ENSP00000257290	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pgfra_human(display_long)|uniprotkb:PDGFRA(gene name)|psi-mi:PDGFRA(display_short)|uniprotkb:CD140 antigen-like family member A(gene name synonym)|uniprotkb:CD140a antigen(gene name synonym)|uniprotkb:Alpha-type platelet-derived growth factor receptor(gene name synonym)|uniprotkb:Alpha platelet-derived growth factor receptor(gene name synonym)|uniprotkb:Platelet-derived growth factor receptor 2(gene name synonym)|uniprotkb:RHEPDGFRA(gene name synonym)|uniprotkb:PDGFR2(gene name synonym)|uniprotkb:Platelet-derived growth factor alpha receptor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001334758.1|refseq:NP_006197.1|refseq:XP_005265800.1|dip:DIP-5736N|ensembl:ENSG00000134853(gene)|ensembl:ENST00000257290(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001775"(cell activation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005018"(platelet-derived growth factor alpha-receptor activity)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005929"(cilium)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030054"(cell junction)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0072277"(metanephric glomerular capillary formation)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000739"(regulation of mesenchymal stem cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027290|interpro:IPR036179|rcsb pdb:1GQ5|rcsb pdb:5GRN|rcsb pdb:5K5X|rcsb pdb:6A32|rcsb pdb:6JOI|rcsb pdb:6JOJ|rcsb pdb:6JOK|rcsb pdb:6JOL|rcsb pdb:7LBF|reactome:R-HSA-1257604|reactome:R-HSA-186763|go:"GO:0060021"(roof of mouth development)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035790"(platelet-derived growth factor receptor-alpha signaling pathway)|go:"GO:0038085"(vascular endothelial growth factor binding)|go:"GO:0038091"(positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|reactome:R-HSA-186797|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674396|reactome:R-HSA-9674401|reactome:R-HSA-9674403|reactome:R-HSA-9674404|reactome:R-HSA-9674428	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:MkKEhNlBrHysJ4mct8Rvqjy2f7U9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75443	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720983|ensembl:ENSP00000264037|ensembl:ENSP00000376543	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tecta_human(display_long)|uniprotkb:TECTA(gene name)|psi-mi:TECTA(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000109927(gene)|ensembl:ENST00000264037(transcript)|ensembl:ENST00000392793(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001507(Endoglin/CD105 antigen)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR017977|interpro:IPR025615|interpro:IPR033026|interpro:IPR036084|interpro:IPR042235|reactome:R-HSA-163125|refseq:NP_005413.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:46dgSE2BJd3p2rc+qpGVr9s01rw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96JM2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96DZ1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q92636	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2947053|ensembl:ENSP00000038176|uniprotkb:Q8IW26|uniprotkb:B4DFB0|uniprotkb:E9PCH0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:fan_human(display_long)|uniprotkb:NSMAF(gene name)|psi-mi:NSMAF(display_short)|uniprotkb:FAN(gene name synonym)|uniprotkb:Factor associated with neutral sphingomyelinase activation(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000035681(gene)|ensembl:ENST00000038176(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q92636|reactome:R-HSA-5626978|refseq:NP_001138244.1|refseq:NP_003571.2|dip:DIP-44106N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:bYfVp3IEco2A9GLNw1kAUC81f9Y9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NS87	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-712159|uniprotkb:Q17RV9|uniprotkb:Q69YL6|uniprotkb:Q96JX7|uniprotkb:Q9H280|ensembl:ENSP00000324020|ensembl:ENSP00000486004	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:kif15_human(display_long)|uniprotkb:Kinesin-like protein 2(gene name synonym)|uniprotkb:Kinesin-like protein 7(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-62(gene name synonym)|uniprotkb:KIF15(gene name)|psi-mi:KIF15(display_short)|uniprotkb:KLP2(gene name synonym)|uniprotkb:KNSL7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000163808(gene)|ensembl:ENSG00000280610(gene)|ensembl:ENST00000326047(transcript)|ensembl:ENST00000627272(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|interpro:IPR031794|interpro:IPR036961|rcsb pdb:4BN2|rcsb pdb:6ZPH|rcsb pdb:6ZPI|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_064627.1|dip:DIP-28133N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:uPKVS0fj2MgjccbxKn6Q5oJ7Fg09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q2M3T9	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720959|ensembl:ENSP00000223026|ensembl:ENSP00000417186|uniprotkb:D0VXG1|uniprotkb:Q9UL99|uniprotkb:Q9Y6T9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hyal4_human(display_long)|uniprotkb:Chondroitin sulfate endo-beta-N-acetylgalactosaminidase(gene name synonym)|uniprotkb:Chondroitin sulfate hydrolase(gene name synonym)|uniprotkb:Hyaluronoglucosaminidase-4(gene name synonym)|uniprotkb:HYAL4(gene name)|psi-mi:HYAL4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000106302(gene)|ensembl:ENST00000223026(transcript)|ensembl:ENST00000476325(transcript)|go:"GO:0004415"(hyalurononglucosaminidase activity)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006027"(glycosaminoglycan catabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030207"(chondroitin sulfate catabolic process)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018155|refseq:NP_036401.2|refseq:XP_011514292.1|refseq:XP_016867400.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:UZGa7hHEa1/Qo5YWtxTeTOwoywA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BZC7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-311024|uniprotkb:A6NED5|uniprotkb:Q5W9G5|uniprotkb:Q76MW7|uniprotkb:Q5SPY5|intact:EBI-3866765|uniprotkb:Q9HC28|ensembl:ENSP00000360666	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:abca2_human(display_long)|uniprotkb:ABCA2(gene name)|psi-mi:ABCA2(display_short)|uniprotkb:ABC2(gene name synonym)|uniprotkb:KIAA1062(gene name synonym)|uniprotkb:ATP-binding cassette transporter 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001597.2|refseq:NP_997698.1|ensembl:ENST00000341511|ensembl:ENSP00000344155|ensembl:ENSP00000360666|refseq:XP_006717059.1|ensembl:ENSG00000107331(gene)|ensembl:ENST00000371605(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001573"(ganglioside metabolic process)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006684"(sphingomyelin metabolic process)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010008"(endosome membrane)|go:"GO:0010872"(regulation of cholesterol esterification)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0032383"(regulation of intracellular cholesterol transport)|go:"GO:0032384"(negative regulation of intracellular cholesterol transport)|go:"GO:0032805"(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060049"(regulation of protein glycosylation)|go:"GO:0061135"(endopeptidase regulator activity)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071072"(negative regulation of phospholipid biosynthetic process)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:0099038"(ceramide floppase activity)|go:"GO:0099040"(ceramide translocation)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0150110"(negative regulation of cholesterol esterification)|go:"GO:1901873"(regulation of post-translational protein modification)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|go:"GO:1904375"(regulation of protein localization to cell periphery)|go:"GO:1905598"(negative regulation of low-density lipoprotein receptor activity)|go:"GO:1905601"(negative regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR026082|interpro:IPR027417|interpro:IPR030366|mint:Q9BZC7|reactome:R-HSA-1369062	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:0R9SMBvlpKcrbgL2J8Q5kaxy/O89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P219	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2807406|uniprotkb:Q86SX7|uniprotkb:Q7L1M2|uniprotkb:Q8IYG8|uniprotkb:Q69YK1|ensembl:ENSP00000374507	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:daple_human(display_long)|uniprotkb:CCDC88C(gene name)|psi-mi:CCDC88C(display_short)|uniprotkb:DAPLE(gene name synonym)|uniprotkb:KIAA1509(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 88C(gene name synonym)|uniprotkb:Dvl-associating protein with a high frequency of leucine residues(gene name synonym)|uniprotkb:Hook-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001073883.2|ensembl:ENSG00000015133(gene)|ensembl:ENST00000389857(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003383"(apical constriction)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031648"(protein destabilization)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR027719|interpro:IPR036872|interpro:IPR043936|reactome:R-HSA-5368598	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:YAtHk2OXKhOgcCerBWS0ObVTLks9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P51610	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9ULF5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2823223|uniprotkb:B4DGU0|uniprotkb:A8K5C6|uniprotkb:Q3MJA4|uniprotkb:Q6DKH6|uniprotkb:Q68CR5|uniprotkb:Q9Y3Z1|ensembl:ENSP00000352655|ensembl:ENSP00000386766	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:s39aa_human(display_long)|uniprotkb:SLC39A10(gene name)|psi-mi:SLC39A10(display_short)|uniprotkb:KIAA1265(gene name synonym)|uniprotkb:ZIP10(gene name synonym)|uniprotkb:Solute carrier family 39 member 10(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011509806.1|refseq:XP_011509807.1|refseq:XP_011509808.1|refseq:XP_005246746.2|refseq:NP_001120729.1|refseq:NP_065075.1|ensembl:ENSG00000196950(gene)|ensembl:ENST00000359634(transcript)|ensembl:ENST00000409086(transcript)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0071578"(zinc ion import across plasma membrane)|go:"GO:1903615"(positive regulation of protein tyrosine phosphatase activity)|interpro:IPR003689(Zinc/iron permease)|reactome:R-HSA-442380	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:j7A/tPe/lJCOscfBZhF1mSe99k09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NS40	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1759868|uniprotkb:Q53QU4|uniprotkb:Q53TB7|uniprotkb:Q53TP9|uniprotkb:Q8IV15|ensembl:ENSP00000331727	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:kcnh7_human(display_long)|uniprotkb:KCNH7(gene name)|psi-mi:KCNH7(display_short)|uniprotkb:ERG3(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.3(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_150375.2|refseq:NP_775185.1|ensembl:ENSG00000184611(gene)|ensembl:ENST00000332142(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:6Y7Q|reactome:R-HSA-1296072	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:MBB426up2VJgMW2Yyqvni1Mo8Fo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P29590	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86TB3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720934|ensembl:ENSP00000354991|uniprotkb:Q6ZUX0|uniprotkb:Q8NAT5|uniprotkb:Q96L95	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:alpk2_human(display_long)|uniprotkb:Heart alpha-protein kinase(gene name synonym)|uniprotkb:ALPK2(gene name)|psi-mi:ALPK2(display_short)|uniprotkb:HAK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000198796(gene)|ensembl:ENST00000361673(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003308"(negative regulation of Wnt signaling pathway involved in heart development)|go:"GO:0005524"(ATP binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905223"(epicardium morphogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR004166(MHCK/EF2 kinase)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_443179.3	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:0YQP/waaMUuwHYYZdux9ovn7nqc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NR81	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-10312733|uniprotkb:Q7Z4U2|uniprotkb:Q4QQQ0|uniprotkb:Q59F00|uniprotkb:Q4FZB6|uniprotkb:Q9H7T4|uniprotkb:Q6NUN3|uniprotkb:A8K5U7|uniprotkb:Q7Z5T2|uniprotkb:Q4QQI5|ensembl:ENSP00000296315	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:arhg3_human(display_long)|uniprotkb:ARHGEF3(gene name)|psi-mi:ARHGEF3(display_short)|uniprotkb:Exchange factor found in platelets and leukemic and neuronal tissues(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001122087.1|refseq:NP_001122088.1|refseq:NP_001276627.1|refseq:NP_062455.1|refseq:XP_005265243.1|refseq:XP_005265244.1|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR044129|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|ensembl:ENSG00000163947(gene)|ensembl:ENST00000296315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:AmxCH/AaD70usjkK+OTh5hoS1ck9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NVR5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-9392930|uniprotkb:Q86TR1|uniprotkb:Q969Z5|uniprotkb:Q86TY8|uniprotkb:C0JAP7|uniprotkb:B9WS54|ensembl:ENSP00000298292	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ktu_human(display_long)|uniprotkb:DNAAF2(gene name)|psi-mi:DNAAF2(display_short)|uniprotkb:C14orf104(gene name synonym)|uniprotkb:Dynein assembly factor 2, axonemal(gene name synonym)|uniprotkb:KTU(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001077377.1|refseq:NP_060609.2|dip:DIP-59041N|ensembl:ENSG00000165506(gene)|ensembl:ENST00000298292(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0036159"(inner dynein arm assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0061966"(establishment of left/right asymmetry)|go:"GO:0070286"(axonemal dynein complex assembly)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR012981(Nop17p)|interpro:IPR034727|interpro:IPR041442|mint:Q9NVR5	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:0ILCb1hggxCP1t8PFo2dClvPsRM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P51003	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-359376|uniprotkb:Q86SX4|uniprotkb:Q86TV0|uniprotkb:Q8IYF5|uniprotkb:Q9BVU2|ensembl:ENSP00000216277	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:papoa_human(display_long)|uniprotkb:PAPOLA(gene name)|psi-mi:PAPOLA(display_short)|uniprotkb:PAP(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_116021.2|refseq:NP_001238935.1|refseq:NP_001238936.1|ensembl:ENSG00000090060(gene)|ensembl:ENST00000216277(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0043631"(RNA polyadenylation)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR014492("Poly(A) polymerase")|interpro:IPR043519|mint:P51003|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001280556.1|refseq:NP_001280557.1|refseq:NP_001280561.1|dip:DIP-27610N|dip:DIP-40865N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rRMBZRE1yFjnO+pnz5g4k+u7hwo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q99551	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2690033|uniprotkb:Q9BVR7|uniprotkb:Q32NF8|uniprotkb:Q53H51|uniprotkb:A4D1E3|ensembl:ENSP00000248643	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mtef1_human(display_long)|uniprotkb:Mitochondrial transcription termination factor 1(gene name synonym)|uniprotkb:MTERF1(gene name)|psi-mi:MTERF1(display_short)|uniprotkb:MTERF(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_008911.1|refseq:NP_001288063.1|refseq:NP_001288064.1|refseq:XP_005250650.1|ensembl:ENSG00000127989(gene)|ensembl:ENST00000351870(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006393"(termination of mitochondrial transcription)|go:"GO:0032392"(DNA geometric change)|go:"GO:0042645"(mitochondrial nucleoid)|interpro:IPR003690(Mitochodrial transcription termination factor-related)|interpro:IPR038538|rcsb pdb:3MVA|rcsb pdb:3MVB|rcsb pdb:3N6S|rcsb pdb:3N7Q|rcsb pdb:5CKY|rcsb pdb:5CO0|rcsb pdb:5CRJ|rcsb pdb:5CRK|reactome:R-HSA-163316|reactome:R-HSA-2151201|refseq:XP_006716189.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:4GkQu9VaQT457D+8Nd/W6DCLlUc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5VZL5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q99650	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2804080|uniprotkb:Q96QJ6|uniprotkb:Q6P4E8|ensembl:ENSP00000274276	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:osmr_human(display_long)|uniprotkb:OSMRB(gene name synonym)|uniprotkb:Interleukin-31 receptor subunit beta(gene name synonym)|uniprotkb:OSMR(gene name)|psi-mi:OSMR(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001310433.1|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0043235"(receptor complex)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040817|reactome:R-HSA-6788467|ensembl:ENSG00000145623(gene)|ensembl:ENST00000274276(transcript)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005900"(oncostatin-M receptor complex)|refseq:NP_001161827.1|refseq:NP_003990.1|refseq:NP_001310434.1|refseq:NP_001310435.1|refseq:NP_001310436.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:9mJAsXVJf+fRZtw21BPg0eDUHZY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N2M4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-12015604|ensembl:ENSP00000280734|uniprotkb:Q96AJ0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tm86a_human(display_long)|uniprotkb:TMEM86A(gene name)|psi-mi:TMEM86A(display_short)|uniprotkb:Transmembrane protein 86A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000151117(gene)|ensembl:ENST00000280734(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0047408"(alkenylglycerophosphocholine hydrolase activity)|go:"GO:0047409"(alkenylglycerophosphoethanolamine hydrolase activity)|interpro:IPR012506(YhhN-like)|refseq:NP_699178.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Fu8c5EllsIP76Ux61/oFGR47eDA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8TBA6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11278147|uniprotkb:O95287|uniprotkb:Q03962|uniprotkb:Q2TS49|uniprotkb:Q9UQQ7|uniprotkb:C9JRU1|ensembl:ENSP00000163416	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:goga5_human(display_long)|uniprotkb:GOLGA5(gene name)|psi-mi:GOLGA5(display_short)|uniprotkb:Cell proliferation-inducing gene 31 protein(gene name synonym)|uniprotkb:Golgin-84(gene name synonym)|uniprotkb:Protein Ret-II(gene name synonym)|uniprotkb:RET-fused gene 5 protein(gene name synonym)|uniprotkb:RETII(gene name synonym)|uniprotkb:RFG5(gene name synonym)|uniprotkb:PIG31(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005104.3|refseq:XP_011535722.1|ensembl:ENSG00000066455(gene)|ensembl:ENST00000163416(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048193"(Golgi vesicle transport)|interpro:IPR019177|reactome:R-HSA-6811438|go:"GO:0031267"(small GTPase binding)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:PtiO2qhE4u4CFxYqL+bqph4lmT09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y6E0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96AY4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-310646|uniprotkb:O95928|uniprotkb:O95929|uniprotkb:Q9NTE4|uniprotkb:Q9UG31|uniprotkb:Q9UGG5|uniprotkb:Q9UPV8|uniprotkb:Q9Y3S5|uniprotkb:Q5W189|ensembl:ENSP00000381003|uniprotkb:K7ZRV2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ttc28_human(display_long)|uniprotkb:TTC28(gene name)|psi-mi:TTC28(display_short)|uniprotkb:KIAA1043(gene name synonym)|uniprotkb:TPR repeat-containing big gene cloned at Keio(gene name synonym)|uniprotkb:TPRBK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001138890.1|ensembl:ENSG00000100154(gene)|ensembl:ENST00000397906(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0051301"(cell division)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024983|ensembl:ENSP00000381003	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:40Pgac+IuZJIi1b1br1E23v0glI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y5P4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-739994|uniprotkb:Q96Q85|uniprotkb:Q96Q88|uniprotkb:Q9H2S7|uniprotkb:Q9H2S8|uniprotkb:Q53YV1|uniprotkb:Q53YV2|uniprotkb:A8K7S2|uniprotkb:B3KUB7|ensembl:ENSP00000261415|ensembl:ENSP00000494110|ensembl:ENSP00000495760	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cert_human(display_long)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001123577.1|refseq:NP_005704.1|refseq:NP_112729.1|refseq:XP_016864408.1|rcsb pdb:2E3P|rcsb pdb:2E3Q|rcsb pdb:2E3R|rcsb pdb:2E3S|rcsb pdb:2RSG|rcsb pdb:2Z9Y|rcsb pdb:2Z9Z|rcsb pdb:3H3Q|rcsb pdb:3H3R|rcsb pdb:3H3S|rcsb pdb:3H3T|rcsb pdb:4HHV|rcsb pdb:5JJD|rcsb pdb:5ZYG|rcsb pdb:5ZYH|rcsb pdb:5ZYI|rcsb pdb:5ZYJ|rcsb pdb:5ZYK|rcsb pdb:5ZYL|rcsb pdb:5ZYM|rcsb pdb:6IEZ|rcsb pdb:6IF0|rcsb pdb:6J0O|rcsb pdb:6J81|reactome:R-HSA-1660661|ensembl:ENSG00000113163(gene)|ensembl:ENST00000261415(transcript)|ensembl:ENST00000643780(transcript)|ensembl:ENST00000644072(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006955"(immune response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0035627"(ceramide transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0097001"(ceramide binding)|go:"GO:0120009"(intermembrane lipid transfer)|go:"GO:0120012"(intermembrane sphingolipid transfer)|go:"GO:0120017"(ceramide transfer activity)|go:"GO:1902387"(ceramide 1-phosphate binding)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002913(Lipid-binding START)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023393|interpro:IPR041952|mint:Q9Y5P4|rcsb pdb:2E3M|rcsb pdb:2E3N|rcsb pdb:2E3O|refseq:XP_006714576.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:AohUpOJQHInz8f5bKv9/Xb5K+/Y9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86VS3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2462188|uniprotkb:C9JPR6|uniprotkb:Q4G0S6|uniprotkb:Q8NEH9|uniprotkb:Q9BWX2|uniprotkb:Q9H9Y1|uniprotkb:Q9UF88|uniprotkb:A8K8W3|uniprotkb:D6RJ88|ensembl:ENSP00000336861	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:iqch_human(display_long)|uniprotkb:IQCH(gene name)|psi-mi:IQCH(display_short)|uniprotkb:Testis development protein NYD-SP5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001271276.1|refseq:NP_001271277.1|refseq:NP_001271278.1|refseq:NP_001026885.1|refseq:NP_001309404.1|refseq:NP_073621.2|ensembl:ENSG00000103599(gene)|ensembl:ENST00000335894(transcript)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR038752	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:TBkqED1baDpk7VUp+3l7l3JkRKQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6PID6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2555404|uniprotkb:O95105|uniprotkb:B2R6G0|ensembl:ENSP00000338533	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ttc33_human(display_long)|uniprotkb:Osmosis-responsive factor(gene name synonym)|uniprotkb:TTC33(gene name)|psi-mi:TTC33(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_036514.1|refseq:XP_011512305.1|ensembl:ENSG00000113638(gene)|ensembl:ENST00000337702(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q6PID6	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:E83noPN1tHU7Ow6YNDDE+vuJkHo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UJU5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-475674|uniprotkb:Q9BYM2|uniprotkb:Q9UDD1|ensembl:ENSP00000360157	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:foxd3_human(display_long)|uniprotkb:HFH2(gene name synonym)|uniprotkb:HNF3/FH transcription factor genesis(gene name synonym)|uniprotkb:FOXD3(gene name)|psi-mi:FOXD3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_036315.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENST00000371116(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-2892247|ensembl:ENSG00000187140(gene)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:zKNoMjX9lFqo0HzMbrSc7W5a0Eg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NXZ2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-10316543|uniprotkb:B4E0C8|uniprotkb:Q6NXR1|ensembl:ENSP00000359361	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ddx43_human(display_long)|uniprotkb:DDX43(gene name)|psi-mi:DDX43(display_short)|uniprotkb:Cancer/testis antigen 13(gene name synonym)|uniprotkb:DEAD box protein 43(gene name synonym)|uniprotkb:DEAD box protein HAGE(gene name synonym)|uniprotkb:HAGE(gene name synonym)|uniprotkb:Helical antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_061135.2|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR036612|ensembl:ENSG00000080007(gene)|ensembl:ENST00000370336(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:66lEHz7ugWNP7M3l2sl1CQTajGs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UJ68	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-19157918|uniprotkb:E9PAS8|uniprotkb:Q52TC4|uniprotkb:Q549N4|uniprotkb:Q66MI7|ensembl:ENSP00000313921|ensembl:ENSP00000493848	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:msra_human(display_long)|uniprotkb:MSRA(gene name)|psi-mi:MSRA(display_short)|uniprotkb:"Peptide-methionine (S)-S-oxide reductase"(gene name synonym)|uniprotkb:Protein-methionine-S-oxide reductase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001129142.1|refseq:NP_001129143.1|refseq:NP_001186658.1|refseq:NP_036463.1|refseq:XP_016868938.1|refseq:XP_016868939.1|ensembl:ENSG00000175806(gene)|ensembl:ENSG00000285250(gene)|ensembl:ENST00000317173(transcript)|ensembl:ENST00000645318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008113"("peptide-methionine (S)-S-oxide reductase activity")|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030091"(protein repair)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036456"("L-methionine-(S)-S-oxide reductase activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR002569(Methionine sulphoxide reductase A)|interpro:IPR036509|reactome:R-HSA-5676934	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:CZgERaM8QiHFfVnCK9PTjXZelFE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O43781	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2602828|uniprotkb:Q7Z752|uniprotkb:Q9HBY6|uniprotkb:Q9HBY7|uniprotkb:D3DT79|ensembl:ENSP00000356076	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dyrk3_human(display_long)|uniprotkb:Regulatory erythroid kinase(gene name synonym)|uniprotkb:DYRK3(gene name)|psi-mi:DYRK3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001004023.1|refseq:NP_003573.2|ensembl:ENSG00000143479(gene)|ensembl:ENST00000367109(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0051301"(cell division)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1903008"(organelle disassembly)|go:"GO:1903432"(regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042521|rcsb pdb:5Y86|refseq:XP_005273372.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:cW2GsEMjkZZIcq3e2YDKGkEYHkg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86SJ6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2970170|uniprotkb:Q8IXV4|uniprotkb:A2RUI1|uniprotkb:Q6Y9L9|ensembl:ENSP00000311859	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dsg4_human(display_long)|uniprotkb:DSG4(gene name)|psi-mi:DSG4(display_short)|uniprotkb:CDHF13(gene name synonym)|uniprotkb:Cadherin family member 13(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001127925.1|refseq:NP_817123.1|ensembl:ENSG00000175065(gene)|ensembl:ENST00000308128(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030057"(desmosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:YA7S6Ip67Rxn8YMb92nThB5nNsc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q08289	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2874501|ensembl:ENSP00000320025|uniprotkb:Q5QJ99|uniprotkb:Q5QJA0|uniprotkb:Q6TME1|uniprotkb:Q6TME3|uniprotkb:A6PVM5|uniprotkb:Q5VVH0|uniprotkb:Q9HD32|uniprotkb:O00304|uniprotkb:Q96NZ5|uniprotkb:Q96NZ4|uniprotkb:Q5VVG9|uniprotkb:Q5VWV6|uniprotkb:Q9BWU2|uniprotkb:Q9Y341|uniprotkb:Q8WX81|uniprotkb:A6PVM8|uniprotkb:Q96NZ3|uniprotkb:Q9Y340|uniprotkb:A6PVM7|uniprotkb:Q6TME2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cacb2_human(display_long)|uniprotkb:CACNB2(gene name)|psi-mi:CACNB2(display_short)|uniprotkb:CACNLB2(gene name synonym)|uniprotkb:MYSB(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)|uniprotkb:Lambert-Eaton myasthenic syndrome antigen B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000165995(gene)|ensembl:ENST00000324631(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0007601"(visual perception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0005262"(calcium channel activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0098793"(presynapse)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|go:"GO:0007528"(neuromuscular junction development)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005444(Voltage-dependent calcium channel, L-type, beta-2 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035605|interpro:IPR036028|reactome:R-HSA-112308|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|reactome:R-HSA-5576892|reactome:R-HSA-5576893|reactome:R-HSA-9662360|refseq:XP_011517961.1|refseq:NP_963884.2|refseq:NP_963864.1|refseq:NP_963865.2|refseq:NP_963887.2|refseq:NP_963890.2|refseq:NP_963891.1|refseq:NP_963866.2|refseq:NP_001316989.1|refseq:NP_000715.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:62aD9Wbg0RTCIwNCGexJvVgKkGE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q92823	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-296950|ensembl:ENSP00000368314|uniprotkb:O15051|uniprotkb:O15179|uniprotkb:Q9UHI3|uniprotkb:Q9UHI4|uniprotkb:A4D0S3|uniprotkb:E9PDA4|uniprotkb:Q14BM2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nrcam_human(display_long)|uniprotkb:NRCAM(gene name)|psi-mi:NRCAM(display_short)|uniprotkb:KIAA0343(gene name synonym)|uniprotkb:NgCAM-related cell adhesion molecule(gene name synonym)|uniprotkb:Neuronal surface protein Bravo(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000091129(gene)|ensembl:ENST00000379028(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001764"(neuron migration)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0043005"(neuron projection)|go:"GO:0043194"(axon initial segment)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|rcsb pdb:1UEN|rcsb pdb:1UEY|reactome:R-HSA-445095|reactome:R-HSA-447038|reactome:R-HSA-447043|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|refseq:NP_001032209.1|refseq:NP_001180511.1|refseq:NP_001180512.1|refseq:NP_001180513.1|refseq:NP_005001.3|refseq:XP_006716066.1|refseq:XP_005250430.1|refseq:XP_016867746.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:5R0by2rhqdhNVUKuigwoClm9gZI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O15042	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-310697|uniprotkb:A0PJ60|uniprotkb:Q0D2M1|uniprotkb:Q2NKQ7|uniprotkb:Q9BR70|intact:EBI-2555384|ensembl:ENSP00000418563	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sr140_human(display_long)|uniprotkb:KIAA0332(gene name synonym)|uniprotkb:U2SURP(gene name)|psi-mi:U2SURP(display_short)|uniprotkb:140 kDa Ser/Arg-rich domain protein(gene name synonym)|uniprotkb:SR140(gene name synonym)|uniprotkb:U2-associated protein SR140(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001073884.1|refseq:NP_001307148.1|refseq:NP_001307149.1|refseq:NP_001307151.1|ensembl:ENSG00000163714(gene)|ensembl:ENST00000473835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR035009|interpro:IPR035967|interpro:IPR035979|reactome:R-HSA-72163|refseq:XP_016861527.1|refseq:XP_016861528.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:STKTFD8Cu0GQMj+HSpn3qgIEw4c9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62258	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P24534	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P60709	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O15409	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-983612|uniprotkb:A0AUV6|uniprotkb:A4D0U8|uniprotkb:Q6ZND1|uniprotkb:Q75MJ3|uniprotkb:Q8IZE0|uniprotkb:Q8N0W2|uniprotkb:Q8N6B7|uniprotkb:Q8N6B8|uniprotkb:Q8NFQ1|uniprotkb:Q8NFQ2|uniprotkb:Q8NFQ3|uniprotkb:Q8NFQ4|uniprotkb:Q8TD74|ensembl:ENSP00000265436|ensembl:ENSP00000377132|uniprotkb:A6NNW4|uniprotkb:B4DLD9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:foxp2_human(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000128573(gene)|ensembl:ENST00000350908(transcript)|ensembl:ENST00000393494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021757"(caudate nucleus development)|go:"GO:0021758"(putamen development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0098582"(innate vocalization behavior)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|mint:O15409|rcsb pdb:2A07|rcsb pdb:2AS5|go:"GO:0046872"(metal ion binding)|refseq:NP_001166237.1|refseq:NP_001166238.1|refseq:NP_055306.1|refseq:NP_683696.2|refseq:NP_683697.2|refseq:NP_683698.2|dip:DIP-29004N|refseq:XP_016868290.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:XRN9auLs2qtK6W3mjHJHAQPbO9s9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q99611	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-3937791|uniprotkb:Q9BUQ2|ensembl:ENSP00000418669	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sps2_human(display_long)|uniprotkb:SEPHS2(gene name)|psi-mi:SEPHS2(display_short)|uniprotkb:SPS2(gene name synonym)|uniprotkb:Selenium donor protein 2(gene name synonym)|uniprotkb:Selenophosphate synthase 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000179918(gene)|ensembl:ENST00000478753(transcript)|go:"GO:0001887"(selenium compound metabolic process)|go:"GO:0004756"(selenide, water dikinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016259"(selenocysteine metabolic process)|go:"GO:0016260"(selenocysteine biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR004536(Selenide water dikinase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR036921|interpro:IPR036676|reactome:R-HSA-2408557|refseq:NP_036380.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:uM3glMd/P5n9oOndt5RKj2yFHUk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IX04	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2339926|uniprotkb:Q96FF5|uniprotkb:Q6P2F0|uniprotkb:Q9NUX7|uniprotkb:B2RB69|uniprotkb:F5H6L6|uniprotkb:B4DL43|uniprotkb:H7BYD6|ensembl:ENSP00000379500	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:uevld_human(display_long)|uniprotkb:UEVLD(gene name)|psi-mi:UEVLD(display_short)|uniprotkb:UEV3(gene name synonym)|uniprotkb:EV and lactate/malate dehydrogenase domain-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001035787.1|refseq:NP_060784.3|refseq:NP_001284700.1|refseq:NP_001248312.1|refseq:NP_001248314.1|refseq:NP_001248311.1|refseq:NP_001248315.1|ensembl:ENSG00000151116(gene)|ensembl:ENST00000396197(transcript)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022383|interpro:IPR036291|rcsb pdb:2I6T|rcsb pdb:3DL2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ZoLQ2ktG7JpK/ocZ+iC65EG5vrc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O76082	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-9846338|uniprotkb:Q6ZQZ8|uniprotkb:Q96EH6|uniprotkb:A2Q0V1|uniprotkb:B2R844|uniprotkb:D3DQ87|ensembl:ENSP00000245407	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:s22a5_human(display_long)|uniprotkb:SLC22A5(gene name)|psi-mi:SLC22A5(display_short)|uniprotkb:OCTN2(gene name synonym)|uniprotkb:High-affinity sodium-dependent carnitine cotransporter(gene name synonym)|uniprotkb:Organic cation/carnitine transporter 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001295051.1|refseq:NP_003051.1|ensembl:ENSG00000197375(gene)|ensembl:ENST00000245407(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009609"(response to symbiotic bacterium)|go:"GO:0015226"(carnitine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015651"(quaternary ammonium group transmembrane transporter activity)|go:"GO:0015697"(quaternary ammonium group transport)|go:"GO:0015879"(carnitine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0060731"(positive regulation of intestinal epithelial structure maintenance)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070715"(sodium-dependent organic cation transport)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1902270"("(R)-carnitine transmembrane transport")|go:"GO:1902603"(carnitine transmembrane transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR004749(Organic cation transport protein)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-HSA-200425|reactome:R-HSA-549127|reactome:R-HSA-5619053|go:"GO:1901235"("(R)-carnitine transmembrane transporter activity")	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:NyUJfbxblUhBIlQftKxtkS8w49k9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P16144	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86YA3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-10962579|ensembl:ENSP00000390505|ensembl:ENSP00000424737|uniprotkb:Q9NUJ4|uniprotkb:B3KQX2|uniprotkb:B4DSN6|uniprotkb:Q6ZU11|uniprotkb:Q9NSW3|uniprotkb:B4DYU8|uniprotkb:G5EA02|uniprotkb:E9PDE1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:zgrf1_human(display_long)|uniprotkb:ZGRF1(gene name)|psi-mi:ZGRF1(display_short)|uniprotkb:C4orf21(gene name synonym)|uniprotkb:GRF-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_060862.3|refseq:XP_005263172.1|ensembl:ENSG00000138658(gene)|ensembl:ENST00000445203(transcript)|ensembl:ENST00000505019(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0071932"(replication fork reversal)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|interpro:IPR018838	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:GARXrh3lxvJfjwWqhYokzoL9dLo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96LM5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-12020542|ensembl:ENSP00000412215|uniprotkb:A8MPU3|uniprotkb:C9J0T8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cd045_human(display_long)|uniprotkb:C4orf45(gene name)|psi-mi:C4orf45(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000164123(gene)|ensembl:ENST00000434826(transcript)|interpro:IPR027814|refseq:NP_689756.2|refseq:XP_016863297.1|refseq:XP_016863298.1|refseq:XP_016863299.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:WmfbS/Dr5JKuK7cP2B8WYN/4h9o9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NS68	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-530381|uniprotkb:Q9BXZ9|uniprotkb:Q9BY00|uniprotkb:Q9NZV2|uniprotkb:B1AM40|uniprotkb:B1AM41|ensembl:ENSP00000371693|uniprotkb:B4E2I6|uniprotkb:A8KA09|uniprotkb:A8KA26	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tnr19_human(display_long)|uniprotkb:Toxicity and JNK inducer(gene name synonym)|uniprotkb:TRADE(gene name synonym)|uniprotkb:UNQ1888/PRO4333(orf name)|uniprotkb:TNFRSF19(gene name)|psi-mi:TNFRSF19(display_short)|uniprotkb:TAJ(gene name synonym)|uniprotkb:TROY(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001191387.1|refseq:NP_001191388.1|refseq:NP_061117.2|refseq:NP_683760.1|ensembl:ENSG00000127863(gene)|ensembl:ENST00000382258(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022342|interpro:IPR034047|mint:Q9NS68|refseq:XP_011533448.1|refseq:XP_005266502.1|refseq:XP_016876140.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:PgTGM9Ovs/NlXZM+4R5i/WSpgwI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13367	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1642811|uniprotkb:O14808|uniprotkb:Q52LY8|uniprotkb:A4Z4T7|uniprotkb:B7ZKR7|uniprotkb:B7ZKS0|intact:EBI-28985906|ensembl:ENSP00000499235	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ap3b2_human(display_long)|uniprotkb:AP3B2(gene name)|psi-mi:AP3B2(display_short)|uniprotkb:Adaptor protein complex AP-3 subunit beta-2(gene name synonym)|uniprotkb:Beta-3B-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-2 large chain(gene name synonym)|uniprotkb:Neuron-specific vesicle coat protein beta-NAP(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001265440.1|refseq:NP_001265441.1|refseq:NP_004635.2|refseq:NP_001335370.1|ensembl:ENST00000535348|ensembl:ENSP00000438721|ensembl:ENST00000535359|ensembl:ENSP00000440984|ensembl:ENSP00000499235|ensembl:ENSG00000103723(gene)|ensembl:ENST00000668990(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|mint:Q13367	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:UpuB/FVFDHPUjAf40y3SxOL9xzA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9H7R5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2876745|ensembl:ENSP00000379702|ensembl:ENSP00000498600|uniprotkb:A8K5T8|intact:EBI-18279043	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:zn665_human(display_long)|uniprotkb:ZNF665(gene name)|psi-mi:ZNF665(display_short)|uniprotkb:ZFP160L(gene name synonym)|uniprotkb:Zinc finger protein 160-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000197497(gene)|ensembl:ENST00000396424(transcript)|ensembl:ENST00000650736(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:XP_005259323.1|refseq:NP_079009.3	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:9/DgjrbkoV2+bFmuLkmFc+msvfM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P04114	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75027	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1236950|uniprotkb:O75345|uniprotkb:Q5VWY7|uniprotkb:Q5VWY8|uniprotkb:Q9BRE1|uniprotkb:Q9UND1|uniprotkb:Q9UP01|uniprotkb:G3XAC4|ensembl:ENSP00000362492	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:abcb7_human(display_long)|uniprotkb:ABCB7(gene name)|psi-mi:ABCB7(display_short)|uniprotkb:ABC7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001258626.1|ensembl:ENSG00000131269(gene)|ensembl:ENST00000373394(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:O75027|reactome:R-HSA-1369007|reactome:R-HSA-2564830|refseq:NP_004290.2|refseq:NP_001258625.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:nsOzSS/enZTkOfd1nRlk8Wv4KRM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5VUJ5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6870855|intact:EBI-28973493|uniprotkb:A6NGH4	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:agap7_human(display_long)|uniprotkb:AGAP7P(gene name)|psi-mi:AGAP7P(display_short)|uniprotkb:AGAP7(gene name synonym)|uniprotkb:Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7 pseudogene(gene name synonym)|uniprotkb:CTGLF4(gene name synonym)|uniprotkb:Centaurin-gamma-like family member 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	mint:Q5VUJ5|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038508|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037278	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:DQH6ZZBczIlxcThYPThO0fnjjW49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96P64	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6871911|ensembl:ENSP00000392513	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:agap4_human(display_long)|uniprotkb:CTGLF1(gene name synonym)|uniprotkb:Centaurin-gamma-like family member 1(gene name synonym)|uniprotkb:MRIP2(gene name synonym)|uniprotkb:AGAP4(gene name)|psi-mi:AGAP4(display_short)|uniprotkb:AGAP8(gene name synonym)|uniprotkb:CTGLF5(gene name synonym)|uniprotkb:Centaurin-gamma-like family member 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001263272.2|ensembl:ENSG00000188234(gene)|ensembl:ENST00000448048(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|refseq:NP_597703.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:H77ItdCXMmkd7GmQ6BaB8kFeRC09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:A6NIR3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6871122|ensembl:ENSP00000363207|uniprotkb:A8MSN5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:agap5_human(display_long)|uniprotkb:CTGLF2(gene name synonym)|uniprotkb:Centaurin-gamma-like family member 2(gene name synonym)|uniprotkb:AGAP5(gene name)|psi-mi:AGAP5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000172650(gene)|ensembl:ENST00000374094(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|refseq:NP_001137472.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:txHWG8xrwrCsT2HhEVFfhsb+WWg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8TF27	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-15105905|uniprotkb:B9EIP7|uniprotkb:D3DWE4	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:aga11_human(display_long)|uniprotkb:AGAP11(gene name)|psi-mi:AGAP11(display_short)|uniprotkb:KIAA1975(gene name synonym)|uniprotkb:Centaurin-gamma-like protein KIAA1975(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_597704.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR038508|interpro:IPR036770|interpro:IPR037278	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:OsIFImgR4cPNj3QLxNUe2p4LC3Q9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5H9L4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6658013|intact:EBI-28978343|uniprotkb:Q9BXU5|uniprotkb:Q9H5R0|uniprotkb:Q86XI4|uniprotkb:Q5H9L6|ensembl:ENSP00000361998	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:taf7l_human(display_long)|uniprotkb:TAF7L(gene name)|psi-mi:TAF7L(display_short)|uniprotkb:Cancer/testis antigen 40(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit Q(gene name synonym)|uniprotkb:TAF2Q(gene name synonym)|uniprotkb:TATA box-binding protein-associated factor 50 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 50 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENST00000324762|ensembl:ENSP00000320283|ensembl:ENST00000356784|ensembl:ENSP00000349235|ensembl:ENSP00000361998|refseq:NP_001161946.1|refseq:NP_079161.3|ensembl:ENSG00000102387(gene)|ensembl:ENST00000372907(transcript)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ZTwtkrGGSZCteSMyVcKIyurpCZ09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6WQI6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720925|ensembl:ENSP00000386143	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hepn1_human(display_long)|uniprotkb:HEPN1(gene name)|psi-mi:HEPN1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000221932(gene)|ensembl:ENST00000408930(transcript)|go:"GO:0005737"(cytoplasm)|refseq:NP_001032647.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:UXrbBevtb2U/8NYWOTCWJUHMQmo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q2LD37	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2683809|uniprotkb:Q9UPP3|uniprotkb:Q8WVD8|uniprotkb:Q9NTI4|uniprotkb:Q9P2H6|uniprotkb:Q4W598|uniprotkb:Q86XA5|uniprotkb:Q5CZA9|uniprotkb:Q9H742|uniprotkb:Q9NTC3|uniprotkb:Q6ZS70|uniprotkb:Q9NT48|uniprotkb:Q6ZV75|ensembl:ENSP00000264501|ensembl:ENSP00000373390	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:k1109_human(display_long)|uniprotkb:FSA(gene name synonym)|uniprotkb:KIAA1371(gene name synonym)|uniprotkb:Fragile site-associated protein(gene name synonym)|uniprotkb:KIAA1109(gene name)|psi-mi:KIAA1109(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_056127.2|refseq:XP_005263344.1|ensembl:ENSG00000138688(gene)|ensembl:ENST00000264501(transcript)|ensembl:ENST00000388738(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0006909"(phagocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0032456"(endocytic recycling)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|interpro:IPR018863|interpro:IPR033616|mint:Q2LD37|refseq:XP_006714407.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:JPb6Yq3X0tdaCFapYIt14WacfpI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96QE4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720906|ensembl:ENSP00000340519|ensembl:ENSP00000378202|uniprotkb:Q17RC9|uniprotkb:Q5YKG6	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lr37b_human(display_long)|uniprotkb:C66 SLIT-like testicular protein(gene name synonym)|uniprotkb:LRRC37B(gene name)|psi-mi:LRRC37B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000185158(gene)|ensembl:ENST00000341671(transcript)|ensembl:ENST00000394713(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR015753(Proline-rich Peptides)|interpro:IPR029423|interpro:IPR032675|interpro:IPR032754|refseq:NP_443120.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tKCdW0ZEhtndUKBQnVlTsXbSiNE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9H477	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-10982959|ensembl:ENSP00000306817|uniprotkb:B4DV96|uniprotkb:A9UK04	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rbsk_human(display_long)|uniprotkb:RBKS(gene name)|psi-mi:RBKS(display_short)|uniprotkb:RBSK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001274509.1|refseq:NP_071411.1|ensembl:ENSG00000171174(gene)|ensembl:ENST00000302188(transcript)|go:"GO:0004747"(ribokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019303"(D-ribose catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002139(Ribokinase)|interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR011877(Ribokinase, bacterial)|interpro:IPR029056|rcsb pdb:2FV7|rcsb pdb:5BYC|rcsb pdb:5BYD|rcsb pdb:5BYE|rcsb pdb:5BYF|rcsb pdb:5C3Y|rcsb pdb:5C3Z|rcsb pdb:5C40|rcsb pdb:5C41|rcsb pdb:6WJZ|rcsb pdb:6WK0|reactome:R-HSA-71336	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:fqb9EruxU8dUiFcZu5dAuq9NO1s9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9ULV4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351384|uniprotkb:Q9NSK5|uniprotkb:B3KU12|ensembl:ENSP00000261401|ensembl:ENSP00000438341|intact:EBI-4404698|uniprotkb:A7MAP0|uniprotkb:A7MAP1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cor1c_human(display_long)|uniprotkb:CORO1C(gene name)|psi-mi:CORO1C(display_short)|uniprotkb:CRNN4(gene name synonym)|uniprotkb:Coronin-3(gene name synonym)|uniprotkb:hCRNN4(gene name synonym)|uniprotkb:CRN2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001263400.1|refseq:NP_055140.1|ensembl:ENSG00000110880(gene)|ensembl:ENST00000261401(transcript)|ensembl:ENST00000541050(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0090148"(membrane fission)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0016197"(endosomal transport)|go:"GO:0097750"(endosome membrane tubulation)|go:"GO:0140285"(endosome fission)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027333|interpro:IPR036322|mint:Q9ULV4|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|refseq:NP_001098707.1|refseq:XP_016874610.1|refseq:XP_016874611.1|refseq:XP_016874612.1|dip:DIP-33138N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Em/LQxjBk9n4tobk5ksyDfFSyeU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5TAG4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11157279|ensembl:ENSP00000478609|ensembl:ENSP00000484391|uniprotkb:O95877|uniprotkb:A0A087WUF1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nbpfc_human(display_long)|uniprotkb:NBPF12(gene name)|psi-mi:NBPF12(display_short)|uniprotkb:COAS1(gene name synonym)|uniprotkb:Chromosome 1 amplified sequence 1(gene name synonym)|uniprotkb:KIAA1245(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000268043(gene)|ensembl:ENST00000617844(transcript)|ensembl:ENST00000617931(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR010630(Protein of unknown function DUF1220)|refseq:NP_001265070.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:KM3xMz8JRIJPqNKt424LyWeAf1o9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N660	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2863570|uniprotkb:A8MPT6|uniprotkb:Q3BBV9|uniprotkb:Q5SXJ2|uniprotkb:Q8IX77|intact:EBI-8476726|intact:MINT-8417699|intact:EBI-28968964|ensembl:ENSP00000462600|ensembl:ENSP00000463178|ensembl:ENSP00000481835	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nbpff_human(display_long)|uniprotkb:NBPF15(gene name)|psi-mi:NBPF15(display_short)|uniprotkb:NBPF16(gene name synonym)|uniprotkb:Neuroblastoma breakpoint family member 16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000481835|ensembl:ENSP00000462600|ensembl:ENSP00000463178|refseq:XP_016856566.1|refseq:NP_001164226.1|refseq:NP_775909.2|ensembl:ENSG00000266338(gene)|ensembl:ENST00000488031(transcript)|ensembl:ENST00000577412(transcript)|ensembl:ENST00000581897(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR010630(Protein of unknown function DUF1220)|mint:Q8N660	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:guAWZ1op9NzRflXheR0SsSzinoM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6P3W6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720897|intact:EBI-28968808|uniprotkb:Q5RHC0|uniprotkb:Q9NWN6	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nbpfa_human(display_long)|uniprotkb:NBPF10(gene name)|psi-mi:NBPF10(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR010630(Protein of unknown function DUF1220)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:q7bIlU/b2TD0O3MQXFlbIQRNolk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5TI25	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2692300|uniprotkb:Q8IX76|uniprotkb:Q5TI23|uniprotkb:Q9UJI9|intact:EBI-28968745	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nbpfe_human(display_long)|uniprotkb:NBPF14(gene name)|psi-mi:NBPF14(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR010630(Protein of unknown function DUF1220)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:gViWHnYZ+M4QRIgKApjNJohfp0g9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q3BBV2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2863585|intact:EBI-28968706	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nbpf8_human(display_long)|uniprotkb:NBPF8(gene name)|psi-mi:NBPF8(display_short)|uniprotkb:NBPF8P(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR010630(Protein of unknown function DUF1220)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:MNZ5h3PahJhkjpbb8el5/n+HVDE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q3BBV0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2804530|uniprotkb:Q9C0H0|uniprotkb:Q8N4E8|uniprotkb:S4R3K2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nbpf1_human(display_long)|uniprotkb:KIAA1693(gene name synonym)|uniprotkb:NBPF1(gene name)|psi-mi:NBPF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0005737"(cytoplasm)|refseq:NP_060410.2|interpro:IPR010630(Protein of unknown function DUF1220)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:df9dRNH9FlktRbcB4eZJiICNysA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N2A0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720891	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cx062_human(display_long)|uniprotkb:LINC00269(gene name)|psi-mi:LINC00269(display_short)|uniprotkb:CXorf62(gene name synonym)|uniprotkb:NCRNA00269(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	-	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ogRQtI+vXsD+nnaJ3MwvUuXtbaU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O43237	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-715294|uniprotkb:Q8TAT3|uniprotkb:A8K6V1|uniprotkb:B4DZP4|ensembl:ENSP00000258198	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dc1l2_human(display_long)|uniprotkb:Dynein light intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:LIC53/55(gene name synonym)|uniprotkb:DYNC1LI2(gene name)|psi-mi:DYNC1LI2(display_short)|uniprotkb:LIC2(gene name synonym)|uniprotkb:DNCLI2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006132.1|refseq:NP_001273086.1|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0051642"(centrosome localization)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|rcsb pdb:6F1T|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|ensembl:ENSG00000135720(gene)|ensembl:ENST00000258198(transcript)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:WUEd3zgPhcKEe10gtoJ+okX8Zps9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UJP4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-8837113|uniprotkb:Q8N4I6|uniprotkb:Q5SY28|uniprotkb:O75057|uniprotkb:Q5SY26|uniprotkb:Q8NF10|uniprotkb:B3KQP2|ensembl:ENSP00000366886	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:klh21_human(display_long)|uniprotkb:KIAA0469(gene name synonym)|uniprotkb:KLHL21(gene name)|psi-mi:KLHL21(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_055666.2|ensembl:ENSG00000162413(gene)|ensembl:ENST00000377658(transcript)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035853"(chromosome passenger complex localization to spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030577|reactome:R-HSA-8951664|reactome:R-HSA-983168	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:u/kx6rw2ps3q3SG+CaqBs3PbOUg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96BY7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2963262|intact:EBI-28979063|ensembl:ENSP00000353010|uniprotkb:Q6ZRE7|uniprotkb:Q96DQ3|uniprotkb:Q9NW80	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:atg2b_human(display_long)|uniprotkb:ATG2B(gene name)|psi-mi:ATG2B(display_short)|uniprotkb:C14orf103(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000066739(gene)|ensembl:ENST00000359933(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|refseq:NP_060506.5|ensembl:ENSP00000353010	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ysf0LJUYoHIKH1vzrhMLgMSPbaM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9HCL3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6381556|ensembl:ENSP00000270001|uniprotkb:A7MD23	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:zfp14_human(display_long)|uniprotkb:ZFP14(gene name)|psi-mi:ZFP14(display_short)|uniprotkb:KIAA1559(gene name synonym)|uniprotkb:ZNF531(gene name synonym)|uniprotkb:Zinc finger protein 531(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000142065(gene)|ensembl:ENST00000270001(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:XP_016882527.1|refseq:NP_065968.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:165uD0mbxJ8N3zgdNrwr3t9Hoxc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q53H47	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-717125|uniprotkb:Q13579|uniprotkb:Q1G668|uniprotkb:Q96F41|uniprotkb:B4DY74|uniprotkb:E7EN68|ensembl:ENSP00000373354	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:setmr_human(display_long)|uniprotkb:SET domain and mariner transposase fusion protein(gene name synonym)|uniprotkb:SETMAR(gene name)|psi-mi:SETMAR(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006506.3|refseq:NP_001230652.1|refseq:NP_001307606.1|refseq:NP_001307607.1|refseq:NP_001263254.1|ensembl:ENSG00000170364(gene)|ensembl:ENST00000358065(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0015074"(DNA integration)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001251"(negative regulation of chromosome organization)|interpro:IPR001214(SET)|interpro:IPR001888(Transposase, type 1)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR036388|interpro:IPR036397|interpro:IPR041426|mint:Q53H47|rcsb pdb:3BO5|rcsb pdb:3F2K|rcsb pdb:3K9J|rcsb pdb:3K9K|go:"GO:0051568"(histone H3-K4 methylation)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:CPDzaHp2gTWPpT90wYydeWbZHRo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P20929	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1049657|uniprotkb:Q15346|uniprotkb:Q53QQ2|uniprotkb:Q53TG8|uniprotkb:F8WCL5|uniprotkb:F8WCP0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nebu_human(display_long)|uniprotkb:NEB(gene name)|psi-mi:NEB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004534.2|interpro:IPR013998(Nebulin)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|rcsb pdb:1ARK|rcsb pdb:1NEB|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)|mint:P20929|interpro:IPR035629|interpro:IPR036028	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:NAMJkXzw1dn4H3amtIbB7xFiYg89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P06858	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-715909|uniprotkb:Q16282|uniprotkb:Q16283|uniprotkb:Q96FC4|uniprotkb:B2R5T9|ensembl:ENSP00000497642	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lipl_human(display_long)|uniprotkb:LPL(gene name)|psi-mi:LPL(display_short)|uniprotkb:LIPD(gene name synonym)|uniprotkb:Phospholipase A1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000228.1|ensembl:ENSG00000175445(gene)|ensembl:ENST00000650287(transcript)|go:"GO:0004465"(lipoprotein lipase activity)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008201"(heparin binding)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009409"(response to cold)|go:"GO:0009749"(response to glucose)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016298"(lipase activity)|go:"GO:0017129"(triglyceride binding)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000734(Lipase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR002330(Lipoprotein lipase)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|mint:P06858|rcsb pdb:6E7K|rcsb pdb:6OAU|rcsb pdb:6OAZ|rcsb pdb:6OB0|rcsb pdb:6WN4|reactome:R-HSA-381340|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:PM82k8/f6nyAUhaTSvIUvjVkbYU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q16760	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-719333|uniprotkb:Q14158|uniprotkb:Q6PK55|uniprotkb:Q8NG53|ensembl:ENSP00000264057|ensembl:ENSP00000487220	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dgkd_human(display_long)|uniprotkb:Diglyceride kinase delta(gene name synonym)|uniprotkb:130 kDa diacylglycerol kinase(gene name synonym)|uniprotkb:DGKD(gene name)|psi-mi:DGKD(display_short)|uniprotkb:KIAA0145(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003639.2|refseq:NP_690618.2|ensembl:ENSG00000077044(gene)|ensembl:ENSG00000280873(gene)|ensembl:ENST00000264057(transcript)|ensembl:ENST00000628356(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010033"(response to organic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090038"(negative regulation of protein kinase C signaling)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037606|interpro:IPR037607|mint:Q16760|rcsb pdb:1R79|rcsb pdb:3BQ7|reactome:R-HSA-114508|dip:DIP-29646N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rMLPKsHWpeF6qbY0eBQcCeFyMo09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P17275	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O60244	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O95996	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O00327	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1794206|uniprotkb:O00313|uniprotkb:O00314|uniprotkb:O00315|uniprotkb:O00316|uniprotkb:O00317|uniprotkb:Q99631|uniprotkb:Q99649|uniprotkb:Q8IUT4|uniprotkb:D3DQW6|uniprotkb:A8K645|uniprotkb:B7WPG7|uniprotkb:B5ME11|uniprotkb:Q4G136|uniprotkb:A2I2N6|intact:EBI-28970920|ensembl:ENSP00000384517|ensembl:ENSP00000385581|ensembl:ENSP00000433571	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:bmal1_human(display_long)|uniprotkb:ARNTL(gene name)|psi-mi:ARNTL(display_short)|uniprotkb:BMAL1(gene name synonym)|uniprotkb:MOP3(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Member of PAS protein 3(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP3(gene name synonym)|uniprotkb:bHLH-PAS protein JAP3(gene name synonym)|uniprotkb:BHLHE5(gene name synonym)|uniprotkb:PASD3(gene name synonym)|uniprotkb:PAS domain-containing protein 3(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENST00000389707|ensembl:ENSP00000374357|ensembl:ENST00000401424|ensembl:ENSP00000385915|ensembl:ENSP00000384517|ensembl:ENST00000403482|ensembl:ENSP00000385897|ensembl:ENSP00000385581|ensembl:ENSP00000433571|refseq:XP_011518414.1|refseq:XP_011518415.1|refseq:NP_001025443.1|refseq:NP_001025444.1|refseq:NP_001169.3|refseq:XP_016873232.1|refseq:NP_001284648.1|refseq:NP_001284651.1|refseq:NP_001284653.1|refseq:XP_016873231.1|refseq:XP_016873235.1|refseq:XP_016873236.1|refseq:XP_016873237.1|dip:DIP-46008N|ensembl:ENSG00000133794(gene)|ensembl:ENST00000403290(transcript)|ensembl:ENST00000403510(transcript)|ensembl:ENST00000529388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4H10|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:UJwUJQAcLUT6aEBNSUZOF6YyvMA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75808	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6149008|uniprotkb:Q9BUW0|uniprotkb:B1B1M4|uniprotkb:Q8WTY9|uniprotkb:Q2KHS2|ensembl:ENSP00000219611	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:can15_human(display_long)|uniprotkb:CAPN15(gene name)|psi-mi:CAPN15(display_short)|uniprotkb:SOLH(gene name synonym)|uniprotkb:Small optic lobes homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005623.1|ensembl:ENSG00000103326(gene)|ensembl:ENST00000219611(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006508"(proteolysis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR022684|interpro:IPR036443|interpro:IPR038765|reactome:R-HSA-1474228	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:GbitF0RjGDdGa0p1IrmWmLfpjfI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9ULT8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-310559|uniprotkb:Q6P445|uniprotkb:Q86VJ1|uniprotkb:Q96F34|uniprotkb:Q9UFZ7|uniprotkb:D3DS86|ensembl:ENSP00000382269|ensembl:ENSP00000450697	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hecd1_human(display_long)|uniprotkb:HECTD1(gene name)|psi-mi:HECTD1(display_short)|uniprotkb:KIAA1131(gene name synonym)|uniprotkb:HECT domain-containing protein 1(gene name synonym)|uniprotkb:E3 ligase for inhibin receptor(gene name synonym)|uniprotkb:EULIR(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HECTD1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000092148(gene)|ensembl:ENST00000399332(transcript)|ensembl:ENST00000553700(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR000569(HECT)|interpro:IPR002110(Ankyrin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010606(Mib-herc2)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020683|interpro:IPR035983|interpro:IPR036770|interpro:IPR037252|interpro:IPR041200|mint:Q9ULT8|rcsb pdb:2DK3|rcsb pdb:3DKM|reactome:R-HSA-983168|rcsb pdb:2LC3|refseq:XP_005267559.2|ensembl:ENSP00000382269|ensembl:ENSP00000450697|refseq:NP_056197.3|dip:DIP-31669N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/l60ZSm+P4Vlc8B79wS7+T1Zvzk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IYJ1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720868|ensembl:ENSP00000373343|uniprotkb:A1L430|uniprotkb:A6NDX6|uniprotkb:A8MSP8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cpne9_human(display_long)|uniprotkb:Copine IX(gene name synonym)|uniprotkb:CPNE9(gene name)|psi-mi:CPNE9(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000144550(gene)|ensembl:ENST00000383832(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|interpro:IPR035892|interpro:IPR036465|interpro:IPR037768|refseq:NP_001295317.1|refseq:NP_705899.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:akYS3HkEq0mr0SAl7wEdu1LxCLo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P42766	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q16832	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1381484|uniprotkb:Q7Z730|ensembl:ENSP00000356898|ensembl:ENSP00000356899|ensembl:ENSP00000400309	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ddr2_human(display_long)|uniprotkb:Discoidin domain-containing receptor tyrosine kinase 2(gene name synonym)|uniprotkb:DDR2(gene name)|psi-mi:DDR2(display_short)|uniprotkb:NTRKR3(gene name synonym)|uniprotkb:TKT(gene name synonym)|uniprotkb:TYRO10(gene name synonym)|uniprotkb:Receptor protein-tyrosine kinase TKT(gene name synonym)|uniprotkb:Tyrosine-protein kinase TYRO10(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase, receptor-related 3(gene name synonym)|uniprotkb:CD167 antigen-like family member B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_006711407.1|refseq:NP_001014796.1|refseq:NP_006173.2|refseq:XP_011507889.1|refseq:XP_011507888.1|dip:DIP-39699N|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR034299|mint:Q16832|rcsb pdb:2WUH|rcsb pdb:2Z4F|rcsb pdb:6FER|rcsb pdb:7AZB|reactome:R-HSA-3000171|ensembl:ENSG00000162733(gene)|ensembl:ENST00000367921(transcript)|ensembl:ENST00000367922(transcript)|ensembl:ENST00000446985(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003416"(endochondral bone growth)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0043235"(receptor complex)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:aWup/fmqKPNU6Zg5aMeU8wKGUPU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8NH70	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720848|ensembl:ENSP00000325128|uniprotkb:Q6IFL3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:o4a16_human(display_long)|uniprotkb:Olfactory receptor OR11-117(gene name synonym)|uniprotkb:OR4A16(gene name)|psi-mi:OR4A16(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000181961(gene)|ensembl:ENST00000314721(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004984"(olfactory receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000725(Olfactory receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-381753|refseq:NP_001005274.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:l51mVTMTUaOJEqJT0Wo+LtQa4+s9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86YZ3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1047017|uniprotkb:Q5U1F4|ensembl:ENSP00000357791|uniprotkb:Q5DT20	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:horn_human(display_long)|uniprotkb:HRNR(gene name)|psi-mi:HRNR(display_short)|uniprotkb:S100A18(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001009931.1|ensembl:ENSG00000197915(gene)|ensembl:ENST00000368801(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031424"(keratinization)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0043163"(cell envelope organization)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR033201|interpro:IPR034325|mint:Q86YZ3|reactome:R-HSA-6798695|ensembl:ENSP00000357791	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:j5ATFM7OQGbf5j+CZpJ3bJoadnc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P34931	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y546	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720831|ensembl:ENSP00000318185|ensembl:ENSP00000360421|uniprotkb:D3DQ46|uniprotkb:Q8N2Q8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lrc42_human(display_long)|uniprotkb:LRRC42(gene name)|psi-mi:LRRC42(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000116212(gene)|ensembl:ENST00000319223(transcript)|ensembl:ENST00000371370(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR039631|refseq:NP_001243338.1|refseq:NP_443172.1|refseq:XP_006710390.1|refseq:XP_006710391.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:mg4TW1YX3ztCDNbt0SH/GUGn/+09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P45983	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-286483|uniprotkb:Q15709|uniprotkb:Q15712|uniprotkb:Q15713|uniprotkb:B7ZLV4|uniprotkb:B5BTZ5|uniprotkb:Q308M2|uniprotkb:D3DX88|uniprotkb:D3DX92|ensembl:ENSP00000363304	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mk08_human(display_long)|uniprotkb:MAPK8(gene name)|psi-mi:MAPK8(display_short)|uniprotkb:JNK1(gene name synonym)|uniprotkb:PRKM8(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 1(gene name synonym)|uniprotkb:JNK-46(gene name synonym)|uniprotkb:SAPK1(gene name synonym)|uniprotkb:Stress-activated protein kinase 1c(gene name synonym)|uniprotkb:SAPK1C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_620634.1|refseq:NP_620637.1|refseq:NP_001310231.1|refseq:NP_001310250.1|refseq:NP_001310251.1|refseq:NP_001310252.1|refseq:NP_001310253.1|refseq:NP_001310254.1|refseq:NP_001310255.1|refseq:NP_001310256.1|refseq:NP_001310257.1|refseq:NP_001310258.1|refseq:NP_001310259.1|refseq:NP_001310260.1|refseq:NP_001265476.1|refseq:NP_001265477.1|dip:DIP-249N|ensembl:ENSG00000107643(gene)|ensembl:ENST00000374189(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009411"(response to UV)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031343"(positive regulation of cell killing)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048511"(rhythmic process)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090045"(positive regulation of deacetylase activity)|go:"GO:0090398"(cellular senescence)|go:"GO:0097441"(basal dendrite)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900740"(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|go:"GO:1902595"(regulation of DNA replication origin binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|mint:P45983|rcsb pdb:1UKH|rcsb pdb:1UKI|rcsb pdb:2G01|rcsb pdb:2GMX|rcsb pdb:2H96|rcsb pdb:2NO3|rcsb pdb:2XRW|rcsb pdb:2XS0|rcsb pdb:3ELJ|rcsb pdb:3O17|rcsb pdb:3O2M|rcsb pdb:3PZE|rcsb pdb:3V3V|rcsb pdb:3VUD|rcsb pdb:3VUG|rcsb pdb:3VUH|rcsb pdb:3VUI|rcsb pdb:3VUK|rcsb pdb:3VUL|rcsb pdb:3VUM|rcsb pdb:4AWI|rcsb pdb:4E73|rcsb pdb:4G1W|rcsb pdb:4HYS|rcsb pdb:4HYU|rcsb pdb:4IZY|rcsb pdb:4L7F|rcsb pdb:4QTD|rcsb pdb:4UX9|rcsb pdb:4YR8|rcsb pdb:5LW1|rcsb pdb:6F5E|rcsb pdb:6ZR5|reactome:R-HSA-111446|reactome:R-HSA-139910|reactome:R-HSA-193648|reactome:R-HSA-205043|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-376172|reactome:R-HSA-450321|reactome:R-HSA-450341|reactome:R-HSA-5693565|reactome:R-HSA-9007892|reactome:R-HSA-9673324	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:8FsGgIJWzsgWymaBqL5+0eQ/7qM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NZJ5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-766076|uniprotkb:A0AVH2|uniprotkb:A0AVH1|uniprotkb:B2RCU9|uniprotkb:Q53QY0|uniprotkb:Q53SB1|uniprotkb:O95846|ensembl:ENSP00000307235	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:e2ak3_human(display_long)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)|uniprotkb:EIF2AK3(gene name)|psi-mi:EIF2AK3(display_short)|uniprotkb:PEK(gene name synonym)|uniprotkb:PERK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004827.4|rcsb pdb:4YZS|rcsb pdb:5SV7|rcsb pdb:7MF0|reactome:R-HSA-381042|rcsb pdb:4X7O|ensembl:ENSG00000172071(gene)|ensembl:ENST00000303236(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070417"(cellular response to cold)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9NZJ5|rcsb pdb:4G31|rcsb pdb:4G34|rcsb pdb:4M7I|rcsb pdb:4X7H|rcsb pdb:4X7J|rcsb pdb:4X7K|rcsb pdb:4X7L|rcsb pdb:4X7N|go:"GO:0051879"(Hsp90 protein binding)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:sjPIYQzmbvq1fvSgn0HR781yf9w9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P12036	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P2B4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UG01	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2815009|uniprotkb:Q9UFJ9|uniprotkb:Q96HW4|uniprotkb:Q86X44|uniprotkb:Q9ULP1|uniprotkb:B2RNU5|uniprotkb:A5PKZ0|intact:EBI-28975847|ensembl:ENSP00000260570	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:if172_human(display_long)|uniprotkb:IFT172(gene name)|psi-mi:IFT172(display_short)|uniprotkb:KIAA1179(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000260570|ensembl:ENST00000359466|ensembl:ENSP00000352443|ensembl:ENST00000674701|ensembl:ENSP00000502275|refseq:NP_056477.1|ensembl:ENSG00000138002(gene)|ensembl:ENST00000260570(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008544"(epidermis development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060348"(bone development)|go:"GO:0061525"(hindgut development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097542"(ciliary tip)|go:"GO:0097598"(sperm cytoplasmic droplet)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036322|reactome:R-HSA-5610787|reactome:R-HSA-5620924	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:qPsplxtaPXhG90gLPi6qmmMIsy89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UPW5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-947297|uniprotkb:Q63HM7|uniprotkb:Q658P5|uniprotkb:Q6P9D6|uniprotkb:Q9H8U6|uniprotkb:Q9H9W8|uniprotkb:Q9NVK1|intact:EBI-2692992|intact:EBI-1104488|uniprotkb:Q5VV80|uniprotkb:B4DIT6|uniprotkb:B4DRZ8|ensembl:ENSP00000349592	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cbpc1_human(display_long)|uniprotkb:AGTPBP1(gene name)|psi-mi:AGTPBP1(display_short)|uniprotkb:CCP1(gene name synonym)|uniprotkb:KIAA1035(gene name synonym)|uniprotkb:NNA1(gene name synonym)|uniprotkb:ATP/GTP-binding protein 1(gene name synonym)|uniprotkb:Nervous system nuclear protein induced by axotomy protein 1 homolog(gene name synonym)|uniprotkb:Protein deglutamylase CCP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_056054.2|refseq:NP_001273644.1|refseq:NP_001273646.1|refseq:XP_005251905.1|refseq:NP_001317630.1|refseq:XP_016870033.1|refseq:XP_016870035.1|ensembl:ENSG00000135049(gene)|go:"GO:0042133"(neurotransmitter metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098958"(retrograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033852|interpro:IPR040626|reactome:R-HSA-8955332|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015631"(tubulin binding)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0035608"(protein deglutamylation)|go:"GO:0035609"(C-terminal protein deglutamylation)|go:"GO:0035610"(protein side chain deglutamylation)|ensembl:ENST00000357081(transcript)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:kzq5xb9lQGQbLjWitxmeKnf1zkg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P20309	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2687785|uniprotkb:Q0VAJ8|uniprotkb:Q9HB60|uniprotkb:Q4QRI3|uniprotkb:Q5VXY2|ensembl:ENSP00000255380|ensembl:ENSP00000482377|ensembl:ENSP00000502013|ensembl:ENSP00000502349|ensembl:ENSP00000502667	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:acm3_human(display_long)|uniprotkb:CHRM3(gene name)|psi-mi:CHRM3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011542343.1|refseq:XP_011542345.1|refseq:XP_011542346.1|refseq:XP_011542348.1|refseq:XP_011542349.1|refseq:NP_000731.1|refseq:NP_001334645.1|refseq:XP_005273089.1|ensembl:ENSG00000133019(gene)|ensembl:ENST00000255380(transcript)|ensembl:ENST00000615928(transcript)|ensembl:ENST00000675184(transcript)|ensembl:ENST00000676433(transcript)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|ensembl:ENST00000676153(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046541"(saliva secretion)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000995(Muscarinic acetylcholine receptor)|interpro:IPR001183(Muscarinic acetylcholine receptor M3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P20309|rcsb pdb:2CSA|reactome:R-HSA-390648|reactome:R-HSA-399997|reactome:R-HSA-416476|refseq:XP_016855641.1|refseq:XP_016855642.1|refseq:XP_016855643.1|refseq:XP_016855644.1|refseq:XP_016855645.1|refseq:XP_016855646.1|refseq:XP_016855647.1|refseq:XP_016855648.1|refseq:XP_016855649.1|refseq:XP_016855650.1|refseq:XP_016855651.1|refseq:XP_016855652.1|dip:DIP-44291N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/arNBsrkXe4KcqIqBw4BEwYZHt49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NXL6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2814634|uniprotkb:Q17RR4|ensembl:ENSP00000264852	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sidt1_human(display_long)|uniprotkb:SIDT1(gene name)|psi-mi:SIDT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001295279.1|refseq:NP_060169.2|ensembl:ENSG00000072858(gene)|ensembl:ENST00000264852(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050658"(RNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|interpro:IPR025958	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tfyz+6DnpnSh7/D7Pg5Dagd723c9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8WYP5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-396018|uniprotkb:Q7Z4E3|uniprotkb:Q8IZA4|uniprotkb:Q96EH9|uniprotkb:Q9Y4Q6|uniprotkb:A6NGM0|uniprotkb:A8MSG9|uniprotkb:A8MZ86|ensembl:ENSP00000497061	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:elys_human(display_long)|uniprotkb:Protein MEL-28(gene name synonym)|uniprotkb:Putative AT-hook-containing transcription factor 1(gene name synonym)|uniprotkb:AHCTF1(gene name)|psi-mi:AHCTF1(display_short)|uniprotkb:Embryonic large molecule derived from yolk sac(gene name synonym)|uniprotkb:ELYS(gene name synonym)|uniprotkb:TMBS62(gene name synonym)|uniprotkb:MSTP108(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_056261.4|refseq:XP_006711821.1|refseq:NP_001310271.1|ensembl:ENSG00000153207(gene)|ensembl:ENST00000648844(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR025151|interpro:IPR032040|mint:Q8WYP5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ydOhjwcpt7Vl1X/urbAgH7EQrtE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O14715	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2560912|intact:EBI-28976328|ensembl:ENSP00000306637|uniprotkb:Q5CZA8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rgpd8_human(display_long)|uniprotkb:RGPD8(gene name)|psi-mi:RGPD8(display_short)|uniprotkb:RANBP2ALPHA(gene name synonym)|uniprotkb:RANBP2L1(gene name synonym)|uniprotkb:RANBP2L3(gene name synonym)|uniprotkb:Ran-binding protein 2-like 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000169629(gene)|ensembl:ENST00000302558(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR000237(GRIP)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR032023|mint:O14715|ensembl:ENSP00000306637|refseq:NP_001157935.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3f8A0lODSljzgqCoEQCUDHEkecE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:A6NKT7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11127981|uniprotkb:B8ZZM4|intact:EBI-28976315|ensembl:ENSP00000386588	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rgpd3_human(display_long)|uniprotkb:RGPD3(gene name)|psi-mi:RGPD3(display_short)|uniprotkb:RGP3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000386588|refseq:NP_001137485.1|ensembl:ENSG00000153165(gene)|ensembl:ENST00000409886(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR000237(GRIP)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR032023	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:P0hLvmzQh4uGFIh4qXxkf47rgzQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q99666	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2511609|intact:EBI-28976430|ensembl:ENSP00000016946|ensembl:ENSP00000330842|uniprotkb:Q53QN2|uniprotkb:Q53T03|uniprotkb:Q59GM7|intact:EBI-2691891|intact:EBI-2555607|uniprotkb:Q9H0B2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rgpd5_human(display_long)|uniprotkb:RGP5(gene name synonym)|uniprotkb:RGPD7(gene name synonym)|uniprotkb:RANBP2L2(gene name synonym)|uniprotkb:RGP6(gene name synonym)|uniprotkb:Ran-binding protein 2-like 1/2(gene name synonym)|uniprotkb:Sperm membrane protein BS-63(gene name synonym)|uniprotkb:RGPD5(gene name)|psi-mi:RGPD5(display_short)|uniprotkb:RGP7(gene name synonym)|uniprotkb:RGPD6(gene name)|psi-mi:RGPD6(display_short)|uniprotkb:RANBP2L1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000015568(gene)|ensembl:ENSG00000183054(gene)|ensembl:ENST00000016946(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|ensembl:ENST00000329516(transcript)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR000237(GRIP)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR032023|refseq:NP_001032955.1|refseq:NP_001116835.1|refseq:NP_005045.2|refseq:NP_115636.1|ensembl:ENSP00000016946|ensembl:ENST00000272454|ensembl:ENSP00000272454|ensembl:ENSP00000330842|ensembl:ENST00000330331|ensembl:ENSP00000330023|ensembl:ENST00000393283|ensembl:ENSP00000376962	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3VCS4B+diYoEK+/iXK6YN6Xp+2A9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y5F6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720806|intact:EBI-28979662|ensembl:ENSP00000252087|uniprotkb:Q9Y5C2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pcdgm_human(display_long)|uniprotkb:PCDHGC5(gene name)|psi-mi:PCDHGC5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000252087|ensembl:ENST00000610789|ensembl:ENSP00000482569|ensembl:ENSG00000240764(gene)|ensembl:ENST00000252087(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0050808"(synapse organization)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR031904|interpro:IPR032455|refseq:NP_061752.1|refseq:NP_115783.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:CgxiE3YSuHfcK9k5XV9j1WG59ps9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q99878	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q16777	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P0C0S8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P20671	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P0C0S5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1199859|uniprotkb:P17317|uniprotkb:Q6I9U0|uniprotkb:B2RD56|ensembl:ENSP00000296417	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2az_human(display_long)|uniprotkb:H2AZ1(gene name)|psi-mi:H2AZ1(display_short)|uniprotkb:H2AFZ(gene name synonym)|uniprotkb:H2AZ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002097.1|ensembl:ENSG00000164032(gene)|ensembl:ENST00000296417(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S5|rcsb pdb:1F66|rcsb pdb:3WA9|rcsb pdb:4CAY|rcsb pdb:4NFT|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5CHL|rcsb pdb:5FUG|rcsb pdb:5Z30|rcsb pdb:6JOU|rcsb pdb:6KO2|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-38593N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:0FrzM1TXlduSQ0NNVl0C9uqCUGI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IUE6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1642157|ensembl:ENSP00000332790	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a2b_human(display_long)|uniprotkb:H2AC21(gene name)|psi-mi:H2AC21(display_short)|uniprotkb:H2A-clustered histone 21(gene name synonym)|uniprotkb:HIST2H2AB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_778235.1|ensembl:ENSG00000184270(gene)|ensembl:ENST00000331128(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q8IUE6|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:1F8W3E3hVpwLzJsW/37w8XshfOE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6FI13	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q93077	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:m00IdooZksbNGKHSsaVvGFVpcko9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BTM1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96KK5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6147668|ensembl:ENSP00000366679	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96QV6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6286100|ensembl:ENSP00000297012	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a1a_human(display_long)|uniprotkb:H2AC1(gene name)|psi-mi:H2AC1(display_short)|uniprotkb:H2A-clustered histone 1(gene name synonym)|uniprotkb:H2AFR(gene name synonym)|uniprotkb:HIST1H2AA(gene name synonym)|uniprotkb:Histone H2A/r(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000164508(gene)|ensembl:ENST00000297012(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q96QV6|rcsb pdb:5GSU|rcsb pdb:5GT0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|dip:DIP-43896N|refseq:NP_734466.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:PPdnPXHZdBxhBy1m8ct38zK0CRc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q7L7L0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P04908	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:4Qno1mMYZB6FdNoojrzulWLVq849606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q71UI9	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2954755|ensembl:ENSP00000308405|uniprotkb:A8MQC5|uniprotkb:Q6PK98|uniprotkb:Q59GV8|uniprotkb:A6NN01|uniprotkb:A6NKY0|uniprotkb:A6NFA8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:h2av_human(display_long)|uniprotkb:H2AZ2(gene name)|psi-mi:H2AZ2(display_short)|uniprotkb:H2A.F/Z(gene name synonym)|uniprotkb:H2A.Z variant histone 2(gene name synonym)|uniprotkb:H2AFV(gene name synonym)|uniprotkb:H2AV(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR007125(Histone core)|interpro:IPR002119(Histone H2A)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:3WAA|rcsb pdb:6M4D|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-9018519|ensembl:ENSG00000105968(gene)|ensembl:ENST00000308153(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|refseq:NP_036544.1|refseq:NP_619541.1|refseq:NP_958844.1|refseq:NP_958924.1|refseq:NP_958925.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:HWEdsnxjwV2Z0BAbsziMwaE/gXE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N3V7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352936|intact:EBI-28982054|ensembl:ENSP00000377789|ensembl:ENSP00000428378|uniprotkb:O15271|uniprotkb:Q9UPX1|uniprotkb:A5PKZ8|uniprotkb:D3DQG8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:synpo_human(display_long)|uniprotkb:SYNPO(gene name)|psi-mi:SYNPO(display_short)|uniprotkb:KIAA1029(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000171992(gene)|ensembl:ENST00000394243(transcript)|ensembl:ENST00000522122(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0097444"(spine apparatus)|go:"GO:1905355"(spine apparatus assembly)|interpro:IPR028753|mint:Q8N3V7|go:"GO:0098886"(modification of dendritic spine)|refseq:NP_001103444.1|refseq:NP_001159680.1|refseq:NP_001159681.1|refseq:NP_009217.3|ensembl:ENST00000307662|ensembl:ENSP00000302139|ensembl:ENSP00000377789|ensembl:ENST00000519664|ensembl:ENSP00000429268|ensembl:ENSP00000428378|refseq:XP_011535854.1|refseq:XP_005268427.1|refseq:XP_005268428.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rCCRVthnF+JTqcwh9lD+GFoWIpo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q12887	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720773|ensembl:ENSP00000261643|ensembl:ENSP00000499396|uniprotkb:B2R6U5|uniprotkb:B4DJ50|uniprotkb:O15334|uniprotkb:Q969F7	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cox10_human(display_long)|uniprotkb:Heme O synthase(gene name synonym)|uniprotkb:COX10(gene name)|psi-mi:COX10(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000006695(gene)|ensembl:ENST00000261643(transcript)|ensembl:ENST00000664217(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0004311"(farnesyltranstransferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006784"(heme A biosynthetic process)|go:"GO:0008495"(protoheme IX farnesyltransferase activity)|go:"GO:0008535"(respiratory chain complex IV assembly)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045333"(cellular respiration)|go:"GO:0048034"(heme O biosynthetic process)|go:"GO:0070069"(cytochrome complex)|interpro:IPR000537(UbiA prenyltransferase)|interpro:IPR006369(Protohaem IX farnesyltransferase)|interpro:IPR016315(Protohaem IX farnesyltransferase, mitochondria)|interpro:IPR030470|reactome:R-HSA-189451|refseq:NP_001294.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wko3rh23hNf/3NBbug7ZRHumvF49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5TDP6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-8860038|uniprotkb:A1L421|uniprotkb:Q0PVN9|uniprotkb:Q0PVP0|uniprotkb:Q9NYJ0|ensembl:ENSP00000359691	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lgsn_human(display_long)|uniprotkb:LGSN(gene name)|psi-mi:LGSN(display_short)|uniprotkb:GLULD1(gene name synonym)|uniprotkb:LGS(gene name synonym)|uniprotkb:Glutamate-ammonia ligase domain-containing protein 1(gene name synonym)|uniprotkb:Lens glutamine synthase-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001137412.1|refseq:NP_057655.2|ensembl:ENSG00000146166(gene)|ensembl:ENST00000370657(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR036651|go:"GO:0006807"(nitrogen compound metabolic process)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ud2SjelS/zHmzVF2DLJ6eWeTvTo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6J272	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-12811067|ensembl:ENSP00000344729|uniprotkb:A6NND9|uniprotkb:Q8N830	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:f166a_human(display_long)|uniprotkb:FAM166A(gene name)|psi-mi:FAM166A(display_short)|uniprotkb:HSD46(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000188163(gene)|go:"GO:0005634"(nucleus)|ensembl:ENST00000344774(transcript)|go:"GO:0036064"(ciliary basal body)|interpro:IPR018902|refseq:NP_001001710.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:AbqaYiW7pI++ciHMdcgK/KX3tjk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8NDF8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2803971|uniprotkb:Q9NW67|uniprotkb:Q9Y6C0|uniprotkb:B4DV38	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:papd5_human(display_long)|uniprotkb:"Non-canonical poly(A) RNA polymerase PAPD5"(gene name synonym)|uniprotkb:TUT3(gene name synonym)|uniprotkb:Terminal guanylyltransferase(gene name synonym)|uniprotkb:TENT4B(gene name)|psi-mi:TENT4B(display_short)|uniprotkb:GLD4(gene name synonym)|uniprotkb:PAP-associated domain-containing protein 5(gene name synonym)|uniprotkb:PAPD5(gene name synonym)|uniprotkb:TRF4-2(gene name synonym)|uniprotkb:Terminal uridylyltransferase 3(gene name synonym)|uniprotkb:Topoisomerase-related function protein 4-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001035375.2|refseq:NP_001035374.2|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0043630"(ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070568"(guanylyltransferase activity)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR040136|interpro:IPR043519|dip:DIP-59183N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Dy+EsRClygf3oq2i8AdtST3ENS49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O60347	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-11603271|uniprotkb:Q9UG83|uniprotkb:Q8WX26|uniprotkb:Q8WX59|uniprotkb:Q5VYA6|ensembl:ENSP00000225235	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tbc12_human(display_long)|uniprotkb:TBC1D12(gene name)|psi-mi:TBC1D12(display_short)|uniprotkb:KIAA0608(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_056003.1|ensembl:ENSG00000108239(gene)|ensembl:ENST00000225235(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:j+46WQm01OVcNT1wwfzUK7Jl7OE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P2K3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-743428|uniprotkb:B3KYA2|uniprotkb:B4DYY7|uniprotkb:Q5VT47|uniprotkb:Q7L9I5|uniprotkb:Q8N5U3|uniprotkb:Q9NV83|ensembl:ENSP00000355972	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rcor3_human(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	rcsb pdb:4CZZ|refseq:NP_001129695.1|refseq:NP_001129696.2|refseq:NP_001129697.1|refseq:NP_060724.1|ensembl:ENSG00000117625(gene)|ensembl:ENST00000367005(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9P2K3	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:hzuKCK7o/85XbN65z8Ua+XNaSJc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O94889	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2510096|uniprotkb:Q7Z3E8|uniprotkb:Q8N125|uniprotkb:A8K612|ensembl:ENSP00000232766	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:klh18_human(display_long)|uniprotkb:KLHL18(gene name)|psi-mi:KLHL18(display_short)|uniprotkb:KIAA0795(gene name synonym)|uniprotkb:OK/SW-cl.74(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_079286.2|ensembl:ENSG00000114648(gene)|ensembl:ENST00000232766(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030603	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:mSO8Uw0maleiD2Ri6RuERO1OpiQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IYU2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-308277|uniprotkb:A8K6U5|uniprotkb:B3KY89|uniprotkb:B4DFM6|uniprotkb:B4DTQ4|uniprotkb:B7Z9X6|uniprotkb:E9PGP0|uniprotkb:Q5VU99|uniprotkb:Q5VUA0|uniprotkb:Q8ND12|uniprotkb:Q9P2M6|ensembl:ENSP00000262903	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hace1_human(display_long)|uniprotkb:KIAA1320(gene name synonym)|uniprotkb:HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1(gene name synonym)|uniprotkb:HACE1(gene name)|psi-mi:HACE1(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HACE1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_065822.2|ensembl:ENSG00000085382(gene)|ensembl:ENST00000262903(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061025"(membrane fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000569(HECT)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR035983|interpro:IPR036770|reactome:R-HSA-983168|refseq:NP_001308009.1|refseq:NP_001308012.1|refseq:NP_001308013.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:zr6DnEjPI0FB03Xsq5eHOJSIcos9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P23515	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720752|ensembl:ENSP00000247271|uniprotkb:E1P659	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:omgp_human(display_long)|uniprotkb:OMG(gene name)|psi-mi:OMG(display_short)|uniprotkb:OMGP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000126861(gene)|ensembl:ENST00000247271(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:P23515|reactome:R-HSA-193634|refseq:NP_002535.3	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tTKo2vTV2DB2ocBMyTnhwef0w+k9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8IXK0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:7si/KU2tHoxviuCr70ncQERDWmY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6UWM9	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720732|ensembl:ENSP00000251566|ensembl:ENSP00000479283|uniprotkb:Q9H6S4	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ud2a3_human(display_long)|uniprotkb:UGT2A3(gene name)|psi-mi:UGT2A3(display_short)|uniprotkb:UNQ2559/PRO6239(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000135220(gene)|ensembl:ENSG00000278216(gene)|ensembl:ENST00000251566(transcript)|ensembl:ENST00000611042(transcript)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0052695"(cellular glucuronidation)|interpro:IPR002213(UDP-glucuronosyl/UDP-glucosyltransferase)|interpro:IPR035595|reactome:R-HSA-156588|refseq:NP_079019.3	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:EDgVvOZhpxsha8hNRL94CRrYNnw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5TA45	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N6C5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-310549|uniprotkb:Q9NTC8|uniprotkb:O15070|uniprotkb:B5MEG2|ensembl:ENSP00000355010|ensembl:ENSP00000498789|uniprotkb:H9KV64	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:igsf1_human(display_long)|uniprotkb:KIAA0364(gene name synonym)|uniprotkb:IGSF1(gene name)|psi-mi:IGSF1(display_short)|uniprotkb:IGDC1(gene name synonym)|uniprotkb:PGSF2(gene name synonym)|uniprotkb:Inhibin-binding protein(gene name synonym)|uniprotkb:Immunoglobulin-like domain-containing protein 1(gene name synonym)|uniprotkb:Pituitary gland-specific factor 2(gene name synonym)|uniprotkb:p120(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001164433.1|refseq:NP_001164434.1|refseq:NP_001546.2|refseq:NP_991402.1|ensembl:ENSG00000147255(gene)|ensembl:ENST00000361420(transcript)|ensembl:ENST00000651556(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0034711"(inhibin binding)|go:"GO:0038102"(activin receptor antagonist activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_001164432.1|refseq:XP_011529632.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:b/PJhWljyz87N8jQ0pNq92Xoxys9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NY65	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356246|ensembl:ENSP00000333326|uniprotkb:B3KPW9|uniprotkb:Q2M3N4|uniprotkb:B2RCX2|uniprotkb:B4DWG3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tba8_human(display_long)|uniprotkb:TUBA8(gene name)|psi-mi:TUBA8(display_short)|uniprotkb:TUBAL2(gene name synonym)|uniprotkb:Alpha-tubulin 8(gene name synonym)|uniprotkb:Tubulin alpha chain-like 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001180343.1|refseq:NP_061816.1|ensembl:ENSG00000183785(gene)|ensembl:ENST00000330423(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|dip:DIP-40751N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:OGRoBAwLchNlK3LtAWkbSbCcxPQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BQ39	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BYX7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-359088|uniprotkb:Q562N5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:actbm_human(display_long)|uniprotkb:FKSG30(orf name)|uniprotkb:POTEKP(gene name)|psi-mi:POTEKP(display_short)|uniprotkb:Kappa-actin(gene name synonym)|uniprotkb:ACTBL3(gene name synonym)|uniprotkb:POTE ankyrin domain family member K(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-HSA-114608|interpro:IPR043129	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Dk63VPZkjnYTXA8YS4jPCXzqs409606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:A5A3E0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6150673|uniprotkb:A6NC34|ensembl:ENSP00000386786	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:potef_human(display_long)|uniprotkb:POTEF(gene name)|psi-mi:POTEF(display_short)|uniprotkb:A26C1B(gene name synonym)|uniprotkb:ANKRD26-like family C member 1B(gene name synonym)|uniprotkb:Chimeric POTE-actin protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001093241.1|ensembl:ENSG00000196604(gene)|ensembl:ENST00000409914(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0005938"(cell cortex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR020902|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:alL+OQ/juWHafyF1GwIiLOPZZso9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6S8J3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-4289913|uniprotkb:Q6S8J4|uniprotkb:Q6S8J8|uniprotkb:Q6S8J5|ensembl:ENSP00000439189|ensembl:ENSP00000507284	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:potee_human(display_long)|uniprotkb:POTEE(gene name)|psi-mi:POTEE(display_short)|uniprotkb:A26C1A(gene name synonym)|uniprotkb:POTE2(gene name synonym)|uniprotkb:ANKRD26-like family C member 1A(gene name synonym)|uniprotkb:Prostate, ovary, testis-expressed protein on chromosome 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000188219(gene)|ensembl:ENST00000356920(transcript)|ensembl:ENST00000683005(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129|reactome:R-HSA-9035034|interpro:IPR020902|refseq:NP_001077007.1|refseq:XP_016859650.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:LMuv4bmAG2/uPyH5LR9q+ickvWI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P68032	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P63261	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P68133	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSP00000355645|uniprotkb:Q5T8M9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000143632(gene)|ensembl:ENST00000366684(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043531"(ADP binding)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|reactome:R-HSA-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001091.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62736	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q562R1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1773495|uniprotkb:Q562R2|uniprotkb:Q562S9|uniprotkb:Q562X8|uniprotkb:B2RPJ1|ensembl:ENSP00000416706	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:actbl_human(display_long)|uniprotkb:ACTBL2(gene name)|psi-mi:ACTBL2(display_short)|uniprotkb:Kappa-actin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001017992.1|ensembl:ENSG00000169067(gene)|ensembl:ENST00000423391(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007409"(axonogenesis)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q562R1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:GTzKP5YRJGH8ocAJW0WEsdQFEdc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P54652	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y2T7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-6598484|ensembl:ENSP00000007699|ensembl:ENSP00000499890|uniprotkb:D3DTP1|uniprotkb:Q8N4P0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ybox2_human(display_long)|uniprotkb:YBX2(gene name)|psi-mi:YBX2(display_short)|uniprotkb:CSDA3(gene name synonym)|uniprotkb:MSY2(gene name synonym)|uniprotkb:Contrin(gene name synonym)|uniprotkb:DNA-binding protein C(gene name synonym)|uniprotkb:Germ cell-specific Y-box-binding protein(gene name synonym)|uniprotkb:MSY2 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000006047(gene)|ensembl:ENSG00000288504(gene)|ensembl:ENST00000007699(transcript)|ensembl:ENST00000672150(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009386"(translational attenuation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0048599"(oocyte development)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|go:"GO:0005634"(nucleus)|refseq:NP_057066.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:8PPtBZIo6esYZJiYj0XZ8ydpH089606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75787	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2512037|ensembl:ENSP00000490083|uniprotkb:B7Z9I3|uniprotkb:Q8NG15|uniprotkb:Q8NBP3|uniprotkb:Q5QTQ7|uniprotkb:Q9UG89|uniprotkb:Q96FV6|uniprotkb:Q9H2P8|uniprotkb:Q96LB5|uniprotkb:Q6T7F5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:renr_human(display_long)|uniprotkb:ATP6AP2(gene name)|psi-mi:ATP6AP2(display_short)|uniprotkb:ATP6IP2(gene name synonym)|uniprotkb:CAPER(gene name synonym)|uniprotkb:ELDF10(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal accessory protein 2"(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal-interacting protein 2"(gene name synonym)|uniprotkb:Vacuolar ATP synthase membrane sector-associated protein M8-9(gene name synonym)|uniprotkb:N14F(gene name synonym)|uniprotkb:Embryonic liver differentiation factor 10(gene name synonym)|uniprotkb:HT028(orf name)|uniprotkb:MSTP009(orf name)|uniprotkb:PSEC0072(orf name)|uniprotkb:ER-localized type I transmembrane adapter(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000182220(gene)|ensembl:ENST00000636580(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0021626"(central nervous system maturation)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048069"(eye pigmentation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR012493(Renin receptor-like)|mint:O75787|rcsb pdb:3LBS|rcsb pdb:3LC8|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:NP_005756.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:v4lEPX23LdYqPi8dQX4MZG+tQZg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P17066	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P0L2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-968587|uniprotkb:Q2HIY1|uniprotkb:Q5VTF9|uniprotkb:Q5VTG0|uniprotkb:Q96SW9|uniprotkb:Q9P251|uniprotkb:D3DTB0|uniprotkb:D3DTB1|ensembl:ENSP00000355884	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mark1_human(display_long)|uniprotkb:MARK1(gene name)|psi-mi:MARK1(display_short)|uniprotkb:KIAA1477(gene name synonym)|uniprotkb:MARK(gene name synonym)|uniprotkb:MAP/microtubule affinity-regulating kinase 1(gene name synonym)|uniprotkb:PAR1 homolog c(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001273057.1|refseq:NP_061120.3|ensembl:ENSP00000355884|ensembl:ENST00000366918|ensembl:ENSP00000355885|dip:DIP-39777N|ensembl:ENSG00000116141(gene)|ensembl:ENST00000366917(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001764"(neuron migration)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033627|mint:Q9P0L2|rcsb pdb:2HAK|rcsb pdb:3OSE|rcsb pdb:6C9D	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/ydFAiGjuUcmwDHO4tEPSSMlVjY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O43182	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720685|intact:EBI-28977626|ensembl:ENSP00000338967|uniprotkb:B2RWQ0|uniprotkb:O43437|uniprotkb:Q9P1B3|uniprotkb:Q9UK81|uniprotkb:Q9UK82	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rhg06_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 6(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RhoGAPX-1(gene name synonym)|uniprotkb:ARHGAP6(gene name)|psi-mi:ARHGAP6(display_short)|uniprotkb:RHOGAP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENST00000303025|ensembl:ENSP00000302312|ensembl:ENSP00000338967|ensembl:ENST00000380718|ensembl:ENSP00000370094|ensembl:ENST00000380736|ensembl:ENSP00000370112|ensembl:ENST00000495242|ensembl:ENSP00000435767|ensembl:ENSG00000047648(gene)|ensembl:ENST00000337414(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR030772|interpro:IPR037863|interpro:IPR041852|reactome:R-HSA-8980692|reactome:R-HSA-9013423|refseq:NP_001274171.1|refseq:NP_006116.2|refseq:NP_038267.1|refseq:NP_038286.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:vkyq8e0fxup//XXOYIWi+ZlBLww9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8NBR6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720660|uniprotkb:B2RTT8|uniprotkb:Q9ULQ6|ensembl:ENSP00000452885	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:miny2_human(display_long)|uniprotkb:Deubiquitinating enzyme MINDY-2(gene name synonym)|uniprotkb:Protein FAM63B(gene name synonym)|uniprotkb:MINDY2(gene name)|psi-mi:MINDY2(display_short)|uniprotkb:FAM63B(gene name synonym)|uniprotkb:KIAA1164(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001035540.1|refseq:NP_001035543.1|ensembl:ENSG00000128923(gene)|ensembl:ENST00000559228(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016807"(cysteine-type carboxypeptidase activity)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071795"(K11-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071796"(K6-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR007518(Protein of unknown function DUF544)|interpro:IPR033979|rcsb pdb:6Z7V|rcsb pdb:6Z49	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:iehKVkXQrscQNpPccqTT/SU7o4A9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5W0Q7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2513899|ensembl:ENSP00000255304|uniprotkb:Q8IYE8|uniprotkb:Q6AI45|uniprotkb:Q14109|uniprotkb:Q8IY30	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:uspl1_human(display_long)|uniprotkb:Ubiquitin-specific peptidase-like protein 1(gene name synonym)|uniprotkb:USPL1(gene name)|psi-mi:USPL1(display_short)|uniprotkb:C13orf22(gene name synonym)|uniprotkb:D13S106(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000132952(gene)|ensembl:ENST00000255304(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009301"(snRNA transcription)|go:"GO:0015030"(Cajal body)|go:"GO:0016926"(protein desumoylation)|go:"GO:0030576"(Cajal body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR028889|interpro:IPR028890|interpro:IPR029388|interpro:IPR033505|interpro:IPR038765|refseq:NP_005791.3|refseq:NP_001308461.1|refseq:NP_001308462.1|refseq:NP_001308463.1|refseq:XP_005266270.1|dip:DIP-47278N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:k1f34cDGMScg/+VAP4YpR62Hrto9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P68366	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|ensembl:ENSP00000248437|uniprotkb:B3KNQ6|intact:EBI-11134566	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005991.1|ensembl:ENSG00000127824(gene)|ensembl:ENST00000248437(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001265481.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13509	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9HCM4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NRY4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6PEY2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2551023|ensembl:ENSP00000318197	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tba3e_human(display_long)|uniprotkb:Alpha-tubulin 3E(gene name synonym)|uniprotkb:TUBA3E(gene name)|psi-mi:TUBA3E(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000152086(gene)|ensembl:ENST00000312988(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|refseq:NP_997195.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:d1yeG615JSUxENnNbx2g6cUVWkI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13748	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355068|uniprotkb:A6NJQ0|uniprotkb:Q5W099|uniprotkb:Q6PEY3|uniprotkb:Q96F18|uniprotkb:P0DPH8|uniprotkb:P0DPH7	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tba3c_human(display_long)|uniprotkb:TUBA3C(gene name)|psi-mi:TUBA3C(display_short)|uniprotkb:TUBA3D(gene name)|psi-mi:TUBA3D(display_short)|uniprotkb:TUBA2(gene name synonym)|uniprotkb:Alpha-tubulin 3C/D(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0005200"(structural constituent of cytoskeleton)|ensembl:ENSG00000075886|ensembl:ENSG00000198033|ensembl:ENSP00000326042|ensembl:ENSP00000382982|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005525"(GTP binding)|go:"GO:0003924"(GTPase activity)|refseq:NP_005992.1|refseq:NP_525125.2|interpro:IPR002452(Alpha tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|ensembl:ENSP00000482878|ensembl:ENST00000618094|reactome:R-HSA-6807878|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-983189|go:"GO:0007017"(microtubule-based process)|go:"GO:0005634"(nucleus)|ensembl:ENST00000321253|ensembl:ENST00000400113|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-8852276|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR023123|mint:Q13748|dip:DIP-34513N|reactome:R-HSA-3371497|reactome:R-HSA-8955332|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0036064"(ciliary basal body)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:mE1Hcdc9AAMMxfxzKB6TfM6RrHE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q00889	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720632|ensembl:ENSP00000292125|uniprotkb:O75244|uniprotkb:Q15224|uniprotkb:Q15235|uniprotkb:Q549K1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:psg6_human(display_long)|uniprotkb:Pregnancy-specific beta-1-glycoprotein 10(gene name synonym)|uniprotkb:Pregnancy-specific beta-1-glycoprotein 12(gene name synonym)|uniprotkb:PSG6(gene name)|psi-mi:PSG6(display_short)|uniprotkb:CGM3(gene name synonym)|uniprotkb:PSG10(gene name synonym)|uniprotkb:PSG12(gene name synonym)|uniprotkb:PSGGB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000170848(gene)|ensembl:ENST00000292125(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007565"(female pregnancy)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-202733|refseq:NP_001027020.1|refseq:NP_002773.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:nd7ijZhYj/SBB8K5BfDtM1uKxsg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O60733	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-12089905|ensembl:ENSP00000333142|ensembl:ENSP00000499555|ensembl:ENSP00000499665|ensembl:ENSP00000499712|uniprotkb:A8K597|uniprotkb:B0QYE8|uniprotkb:O75645|uniprotkb:Q8N452|uniprotkb:Q9UG29|uniprotkb:Q9UIT0|uniprotkb:Q9Y671	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:plpl9_human(display_long)|uniprotkb:PLA2G6(gene name)|psi-mi:PLA2G6(display_short)|uniprotkb:Group VI phospholipase A2(gene name synonym)|uniprotkb:Intracellular membrane-associated calcium-independent phospholipase A2 beta(gene name synonym)|uniprotkb:PLPLA9(gene name synonym)|uniprotkb:Patatin-like phospholipase domain-containing protein 9(gene name synonym)|uniprotkb:2-lysophosphatidylcholine acylhydrolase(gene name synonym)|uniprotkb:Palmitoyl-CoA hydrolase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000184381(gene)|ensembl:ENST00000332509(transcript)|ensembl:ENST00000660610(transcript)|ensembl:ENST00000663895(transcript)|ensembl:ENST00000667521(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007613"(memory)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901339"(regulation of store-operated calcium channel activity)|go:"GO:2000304"(positive regulation of ceramide biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482839|reactome:R-HSA-2029485|reactome:R-HSA-6811436|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042311"(vasodilation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046338"(phosphatidylethanolamine catabolic process)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046473"(phosphatidic acid metabolic process)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090238"(positive regulation of arachidonic acid secretion)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|refseq:NP_001004426.1|refseq:NP_001186491.1|refseq:NP_003551.2|refseq:XP_005261821.1|refseq:XP_005261822.1|refseq:XP_005261823.1|refseq:XP_006724395.1|refseq:XP_016884470.1|refseq:XP_016884471.1|refseq:XP_016884477.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3kvF2S7ye5ubo/5f3O0Oa+tuDCI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O15111	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-81249|uniprotkb:O14666|uniprotkb:Q13132|uniprotkb:Q5W0I4|uniprotkb:Q92467|ensembl:ENSP00000359424|intact:EBI-28970970	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ikka_human(display_long)|uniprotkb:CHUK(gene name)|psi-mi:CHUK(display_short)|uniprotkb:IKKA(gene name synonym)|uniprotkb:TCF16(gene name synonym)|uniprotkb:I-kappa-B kinase 1(gene name synonym)|uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)|uniprotkb:Transcription factor 16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001269.3|ensembl:ENSP00000359424|ensembl:ENSG00000213341(gene)|ensembl:ENST00000370397(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0010034"(response to acetate)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022007|interpro:IPR041185|mint:O15111|rcsb pdb:3BRT|rcsb pdb:5EBZ|rcsb pdb:5TQW|rcsb pdb:5TQX|rcsb pdb:5TQY|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-198323|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5674400|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|dip:DIP-27526N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:FVB/gXjSBTB9hdq9pycQogxesms9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P12111	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2465936|ensembl:ENSP00000295550|uniprotkb:Q53QF4|uniprotkb:Q53QF6|uniprotkb:Q16501|uniprotkb:B4E3U5|uniprotkb:E9PGQ9|uniprotkb:A8MT30|uniprotkb:B7ZMJ7|uniprotkb:E9PFQ6	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:co6a3_human(display_long)|uniprotkb:COL6A3(gene name)|psi-mi:COL6A3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042383"(sarcolemma)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|go:"GO:0005615"(extracellular space)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR020901|interpro:IPR036116|interpro:IPR036465|interpro:IPR036880|interpro:IPR041900|rcsb pdb:1KNT|rcsb pdb:1KTH|rcsb pdb:1KUN|rcsb pdb:2KNT|rcsb pdb:6SNK|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8948216|mint:P12111|ensembl:ENSG00000163359(gene)|ensembl:ENST00000295550(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005589"(collagen type VI trimer)|refseq:NP_476506.3|refseq:NP_004360.2|refseq:NP_476508.2|refseq:NP_476505.3|refseq:NP_476507.3|refseq:XP_016858792.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:7xGWLmEvMdbEeoy4MT+iheiQkB09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BZU1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1054307	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:q9bzu1_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR001377(Ribosomal protein S6e)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:MTKuQ8iOJh8xtb1MoNvzzjByZk09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P58505	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2115873|uniprotkb:B3KPI1|uniprotkb:Q8N7N9|ensembl:ENSP00000291691	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cu058_human(display_long)|uniprotkb:C21orf58(gene name)|psi-mi:C21orf58(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001273391.1|refseq:NP_001273392.1|refseq:XP_011527921.1|refseq:XP_011527922.1|refseq:XP_011527927.1|refseq:NP_478060.2|refseq:XP_006724081.1|refseq:XP_016883881.1|refseq:XP_016883882.1|refseq:XP_016883880.1|refseq:XP_005261205.1|refseq:NP_001273405.1|refseq:NP_001273406.1|refseq:XP_011527928.1|refseq:XP_011527929.1|refseq:XP_016883878.1|refseq:XP_016883879.1|refseq:XP_016883877.1|ensembl:ENSG00000160298(gene)|ensembl:ENST00000291691(transcript)|interpro:IPR027904|interpro:IPR038915	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:PTicXeyOaqNkehIeGEpgZw+9Yfw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P202	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-310886|uniprotkb:A5PKU1|uniprotkb:A5PKZ9|uniprotkb:Q5TAV0|uniprotkb:Q5TAU9|uniprotkb:Q96MZ9|uniprotkb:Q9H9F4|uniprotkb:Q9UFZ3|uniprotkb:Q5TAV1|uniprotkb:Q5TAV2|ensembl:ENSP00000354623|uniprotkb:A0A0C4DFT9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:whrn_human(display_long)|uniprotkb:WHRN(gene name)|psi-mi:WHRN(display_short)|uniprotkb:Autosomal recessive deafness type 31 protein(gene name synonym)|uniprotkb:DFNB31(gene name synonym)|uniprotkb:KIAA1526(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001077354.2|refseq:NP_001166896.1|refseq:NP_056219.3|refseq:NP_001333819.1|ensembl:ENSG00000095397(gene)|ensembl:ENST00000362057(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002141"(stereocilia ankle link)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0030426"(growth cone)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:1990227"(paranodal junction maintenance)|go:"GO:1990696"(USH2 complex)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR033028|interpro:IPR036034|rcsb pdb:1UEZ|rcsb pdb:1UF1|rcsb pdb:1UFX|rcsb pdb:6KZ1|reactome:R-HSA-9662360|reactome:R-HSA-9662361	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:s7fXeKbtwBH+5tR2J0wo4EgAWL89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P28331	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q6DCA4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720628	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:q6dca4_human(display_long)|uniprotkb:LOC554248(gene name)|psi-mi:LOC554248(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	-	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:9qpXuOB1Jdn9Pyuvf4Oj8TdQAXE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q00610	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UM54	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-350606|uniprotkb:Q5TEM5|uniprotkb:Q5TEM6|uniprotkb:Q5TEM7|uniprotkb:Q9BZZ7|uniprotkb:Q9UEG2|uniprotkb:A6H8V4|uniprotkb:E1P540	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:myo6_human(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0051046"(regulation of secretion)|refseq:NP_004990.3|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2N0Z|rcsb pdb:2N10|rcsb pdb:2N11|go:"GO:0060001"(minus-end directed microfilament motor activity)|rcsb pdb:2N12|rcsb pdb:2N13|rcsb pdb:6E5N|rcsb pdb:6J56|reactome:R-HSA-190873|reactome:R-HSA-399719|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|refseq:NP_001287828.1|mint:Q9UM54|dip:DIP-33123N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:LYtnU7aRzVE/LDFhZgcK5IvahC09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75643	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_054733.2|ensembl:ENSG00000144028(gene)|ensembl:ENST00000323853(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:XP_016859092.1|dip:DIP-31659N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q86W24	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720603|ensembl:ENSP00000299481|uniprotkb:Q7RTR6	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nal14_human(display_long)|uniprotkb:Nucleotide-binding oligomerization domain protein 5(gene name synonym)|uniprotkb:NLRP14(gene name)|psi-mi:NLRP14(display_short)|uniprotkb:NALP14(gene name synonym)|uniprotkb:NOD5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000158077(gene)|ensembl:ENST00000299481(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR004020(Pyrin)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q86W24|rcsb pdb:4N1J|rcsb pdb:4N1K|rcsb pdb:4N1L|refseq:NP_789792.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:MDZ9wNlt6dVpOaHhuIjjwwsiG+g9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P13639	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O43707	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|ensembl:ENSP00000252699|ensembl:ENSP00000489220|uniprotkb:A4K467	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004915.2|ensembl:ENSG00000130402(gene)|ensembl:ENSG00000282844(gene)|ensembl:ENST00000252699(transcript)|ensembl:ENST00000634960(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|dip:DIP-33179N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P33992	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-359410|ensembl:ENSP00000216122|uniprotkb:O60785|uniprotkb:Q14578|uniprotkb:Q9BTJ4|uniprotkb:Q9BWL8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mcm5_human(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:CDC46 homolog(gene name synonym)|uniprotkb:P1-CDC46(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000100297(gene)|ensembl:ENST00000216122(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33992|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_006730.2|reactome:R-HSA-69052|reactome:R-HSA-68962|dip:DIP-27578N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:WjJ4lSpADQFtwT0WnumbRHl/lPw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q08380	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P46087	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356811|uniprotkb:A1A4Z3|uniprotkb:Q0P5S5|uniprotkb:Q58F30|uniprotkb:B3KPD6|uniprotkb:Q05BA7|uniprotkb:Q3KQS4|ensembl:ENSP00000313272|ensembl:ENSP00000444437	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nop2_human(display_long)|uniprotkb:NOP2(gene name)|psi-mi:NOP2(display_short)|uniprotkb:NSUN1(gene name synonym)|uniprotkb:Proliferating-cell nucleolar antigen p120(gene name synonym)|uniprotkb:Proliferation-associated nucleolar protein p120(gene name synonym)|uniprotkb:NOL1(gene name synonym)|uniprotkb:Nucleolar protein 2 homolog(gene name synonym)|uniprotkb:Nucleolar protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001028886.1|refseq:NP_006161.2|refseq:NP_001245237.1|refseq:NP_001245238.1|refseq:NP_001245239.1|refseq:XP_005253748.1|ensembl:ENSG00000111641(gene)|ensembl:ENST00000322166(transcript)|ensembl:ENST00000537442(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR011023(Nop2p)|interpro:IPR012586(P120R)|interpro:IPR018314|interpro:IPR023267|interpro:IPR023273|interpro:IPR029063|interpro:IPR031341|mint:P46087|reactome:R-HSA-6790901|reactome:R-HSA-8869496	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:CvYaCDv8N8OvS0lPFy8jFEFaOTA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9ULX6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O60825	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-764425|uniprotkb:O60824|uniprotkb:Q5VVQ4|uniprotkb:Q9H3P1|uniprotkb:Q5VVQ3|ensembl:ENSP00000356047	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:f262_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase heart-type isozyme(gene name synonym)|uniprotkb:PFKFB2(gene name)|psi-mi:PFKFB2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001018063.1|refseq:NP_006203.2|ensembl:ENSG00000123836(gene)|ensembl:ENST00000367080(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0033133"(positive regulation of glucokinase activity)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|mint:O60825|rcsb pdb:5HTK|reactome:R-HSA-9634600	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:VAIXM3xzM91KrxL92RdTLkqVcaM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P17858	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-487243|uniprotkb:Q96A64|uniprotkb:Q96IH4|uniprotkb:Q9BR91|ensembl:ENSP00000269848	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pfkal_human(display_long)|uniprotkb:PFKL(gene name)|psi-mi:PFKL(display_short)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001002021.2|refseq:NP_002617.3|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P17858|reactome:R-HSA-6798695|reactome:R-HSA-70171|ensembl:ENSG00000141959(gene)|ensembl:ENST00000349048(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:lP9/V5WcCl5rLpy4QEZnWkLCCcQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q5SSJ5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2880687|ensembl:ENSP00000312625|ensembl:ENSP00000403039|uniprotkb:Q5SWC6|uniprotkb:Q6PIM9|uniprotkb:B3KMZ8|uniprotkb:A8K5D7|uniprotkb:Q8NDF0|uniprotkb:Q05BI0|uniprotkb:B4E210|uniprotkb:A6NI71|uniprotkb:Q9UHY0|uniprotkb:Q5SSJ6	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hp1b3_human(display_long)|uniprotkb:HP1BP3(gene name)|psi-mi:HP1BP3(display_short)|uniprotkb:Protein HP1-BP74(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000127483(gene)|ensembl:ENST00000312239(transcript)|ensembl:ENST00000438032(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|mint:Q5SSJ5|rcsb pdb:2RQP|go:"GO:0005694"(chromosome)|refseq:XP_016856882.1|refseq:XP_016856883.1|refseq:XP_011539834.1|refseq:XP_011539835.1|refseq:XP_011539836.1|refseq:NP_057371.2|refseq:XP_005245932.1|refseq:XP_005245933.1|refseq:XP_005245934.1|refseq:XP_005245935.1|refseq:XP_005245936.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:kLFithZZv+Qn9YLElEnX81awKDw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P08670	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O43242	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NZI8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q15428	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2462271|uniprotkb:O75245|uniprotkb:B2RBU1|uniprotkb:D6W605|intact:EBI-28985293|ensembl:ENSP00000221494	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sf3a2_human(display_long)|uniprotkb:SF3A2(gene name)|psi-mi:SF3A2(display_short)|uniprotkb:SAP62(gene name synonym)|uniprotkb:Spliceosome-associated protein 62(gene name synonym)|uniprotkb:SF3a66(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_009096.2|ensembl:ENSP00000221494|dip:DIP-42521N|ensembl:ENSG00000104897(gene)|ensembl:ENST00000221494(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR031781|interpro:IPR036236|mint:Q15428|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ME4xzpqT37HjPl/xy683FS1Vns89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O14929	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P07237	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P30101	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8NEE8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-14404749|ensembl:ENSP00000362386|uniprotkb:B4DYG4|uniprotkb:B5ME24|uniprotkb:Q5JU66|uniprotkb:Q96M72	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ttc16_human(display_long)|uniprotkb:TTC16(gene name)|psi-mi:TTC16(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR019734|ensembl:ENSG00000167094(gene)|ensembl:ENST00000373289(transcript)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_001303966.1|refseq:NP_659402.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:pUbXwmKSvtpZiQ/LWeQNe6i0s6I9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O00425	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q00325	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325	-	-	crc64:78714C85931B22D5	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P41091	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1054228|uniprotkb:B5BTZ4|intact:EBI-11602611|uniprotkb:A0A024RBY4|uniprotkb:A8K2Y2|uniprotkb:B2R5N2|uniprotkb:Q53HK3|ensembl:ENSP00000253039	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:if2g_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit gamma X(gene name synonym)|uniprotkb:EIF2S3(gene name)|psi-mi:EIF2S3(display_short)|uniprotkb:EIF2G(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001406.1|ensembl:ENSG00000130741(gene)|ensembl:ENST00000253039(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR044127|interpro:IPR044128|rcsb pdb:6FEC|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|interpro:IPR027417	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:6uBTiGTvEKMfS0NqkKGIaSR61j89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P17050	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720565|ensembl:ENSP00000379680|ensembl:ENSP00000384603|ensembl:ENSP00000385283	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nagab_human(display_long)|uniprotkb:Alpha-galactosidase B(gene name synonym)|uniprotkb:NAGA(gene name)|psi-mi:NAGA(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0070062"(extracellular exosome)|interpro:IPR000111(Glycoside hydrolase, clan GH-D)|interpro:IPR002241(Glycoside hydrolase, family 27)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR035373|rcsb pdb:3H53|rcsb pdb:3H54|rcsb pdb:3H55|rcsb pdb:3IGU|rcsb pdb:4DO4|rcsb pdb:4DO5|rcsb pdb:4DO6|ensembl:ENSG00000198951(gene)|ensembl:ENST00000396398(transcript)|ensembl:ENST00000402937(transcript)|ensembl:ENST00000403363(transcript)|go:"GO:0004557"(alpha-galactosidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0008456"(alpha-N-acetylgalactosaminidase activity)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0016139"(glycoside catabolic process)|go:"GO:0019377"(glycolipid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046477"(glycosylceramide catabolic process)|refseq:NP_000253.1|refseq:XP_005261672.1|refseq:XP_005261673.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:zO65W1bBcy1649o5f2nVvrVkYCk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P22695	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q01518	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N	-	-	crc64:7789D1FAC0D1AB7B	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P61962	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P02679	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1034422|uniprotkb:P04469|uniprotkb:P04470|uniprotkb:Q96A14|uniprotkb:Q96KJ3|uniprotkb:A8K057|uniprotkb:Q53Y18|uniprotkb:Q9UC62|uniprotkb:Q9UC63|uniprotkb:Q9UCF3|ensembl:ENSP00000336829	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:fibg_human(display_long)|uniprotkb:FGG(gene name)|psi-mi:FGG(display_short)|uniprotkb:PRO2061(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000500.2|refseq:NP_068656.2|ensembl:ENSG00000171557(gene)|ensembl:ENST00000336098(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0009306"(protein secretion)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0036345"(platelet maturation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR037581|mint:P02679|rcsb pdb:1DUG|rcsb pdb:1FIB|rcsb pdb:1FIC|rcsb pdb:1FID|rcsb pdb:1FZA|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2FIB|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2HWL|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2VDO|rcsb pdb:2VDP|rcsb pdb:2VDQ|rcsb pdb:2VDR|rcsb pdb:2VR3|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Y7L|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:2Q9I|rcsb pdb:3FIB|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4B60|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29644N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:QKWesyU4/fduceFtu5zq31oGhYI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P55209	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UKZ4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20720508|ensembl:ENSP00000360171|uniprotkb:B2RTR5|uniprotkb:Q5JZ17	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ten1_human(display_long)|uniprotkb:Protein Odd Oz/ten-m homolog 1(gene name synonym)|uniprotkb:Tenascin-M1(gene name synonym)|uniprotkb:Teneurin transmembrane protein 1(gene name synonym)|uniprotkb:TENM1(gene name)|psi-mi:TENM1(display_short)|uniprotkb:ODZ1(gene name synonym)|uniprotkb:TNM1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000360171|ensembl:ENST00000422452|ensembl:ENSP00000403954|ensembl:ENSG00000009694(gene)|ensembl:ENST00000371130(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006955"(immune response)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048666"(neuron development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR006530(YD repeat)|interpro:IPR009471(Teneurin intracellular, N-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR028916|refseq:NP_001156750.1|refseq:NP_001156751.1|refseq:NP_055068.2|refseq:XP_011529532.1|refseq:XP_016884703.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:x27qgHHCjC0sbvbyYrXElwk3S+s9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q3ZCQ8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P05141	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13561	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-715074|uniprotkb:Q86YN2|uniprotkb:Q9BW17|uniprotkb:B2RBK5|ensembl:ENSP00000447824	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dctn2_human(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:DCTN2(gene name)|psi-mi:DCTN2(display_short)|uniprotkb:DCTN50(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006391.1|refseq:NP_001248341.1|refseq:NP_001248342.1|dip:DIP-37545N|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|ensembl:ENSG00000175203(gene)|ensembl:ENST00000548249(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q13561|reactome:R-HSA-2132295	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:JrL5jUtArek+zqmCkPKomnjuSf09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13151	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P52907	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P25786	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P25787	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P09972	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2952751|ensembl:ENSP00000226253|ensembl:ENSP00000378731|uniprotkb:Q6P0L5|uniprotkb:Q3SYL3|uniprotkb:Q6FH94|uniprotkb:B2R5R3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:aldoc_human(display_long)|uniprotkb:ALDOC(gene name)|psi-mi:ALDOC(display_short)|uniprotkb:ALDC(gene name synonym)|uniprotkb:Brain-type aldolase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P09972|rcsb pdb:1XFB|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000109107(gene)|ensembl:ENST00000226253(transcript)|ensembl:ENST00000395321(transcript)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:NP_005156.1|refseq:XP_011522858.1|refseq:XP_005258006.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:0ZRiaxKG2+jvyJw6MHu1cWGFEhk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y224	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1104547|ensembl:ENSP00000261700	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P02765	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1223374|uniprotkb:O14961|uniprotkb:O14962|uniprotkb:Q9P152|uniprotkb:A8K9N6|uniprotkb:B2R7G1|ensembl:ENSP00000393887	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:fetua_human(display_long)|uniprotkb:AHSG(gene name)|psi-mi:AHSG(display_short)|uniprotkb:FETUA(gene name synonym)|uniprotkb:PRO2743(orf name)|uniprotkb:Ba-alpha-2-glycoprotein(gene name synonym)|uniprotkb:Alpha-2-Z-globulin(gene name synonym)|uniprotkb:Fetuin-A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001613.2|ensembl:ENSG00000145192(gene)|ensembl:ENST00000411641(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006907"(pinocytosis)|go:"GO:0006953"(acute-phase response)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001363(Proteinase inhibitor I25C, fetuin, conserved site)|interpro:IPR025760|mint:P02765|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-6798695|reactome:R-HSA-8957275	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:2SoUaMokkmtdRNazI9k95s9E9H49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P49207	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1051893|uniprotkb:Q6FG66|uniprotkb:Q9BUZ2|ensembl:ENSP00000378160|ensembl:ENSP00000378162|ensembl:ENSP00000378163|ensembl:ENSP00000423316|ensembl:ENSP00000423983	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl34_human(display_long)|uniprotkb:RPL34(gene name)|psi-mi:RPL34(display_short)|uniprotkb:Large ribosomal subunit protein eL34(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000986.2|refseq:NP_296374.1|refseq:NP_001306161.1|refseq:NP_001306163.1|refseq:NP_001306164.1|refseq:NP_001306165.1|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:6Y6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR008195(Ribosomal protein L34e)|interpro:IPR018065|mint:P49207|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|ensembl:ENSG00000109475(gene)|ensembl:ENST00000394665(transcript)|ensembl:ENST00000394667(transcript)|ensembl:ENST00000394668(transcript)|ensembl:ENST00000502534(transcript)|ensembl:ENST00000506397(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:NSGnIE6uSimeraPQ7ZZ+xRugABg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NQ92	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1642558|uniprotkb:E1P656|uniprotkb:A6NP14|uniprotkb:Q96EF5|uniprotkb:Q96P75|ensembl:ENSP00000304327	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:coprs_human(display_long)|uniprotkb:COPRS(gene name)|psi-mi:COPRS(display_short)|uniprotkb:C17orf79(gene name synonym)|uniprotkb:COPR5(gene name synonym)|uniprotkb:Cooperator of PRMT5(gene name synonym)|uniprotkb:Protein TTP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_060875.2|ensembl:ENSG00000172301(gene)|ensembl:ENST00000302362(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0042393"(histone binding)|go:"GO:0043985"(histone H4-R3 methylation)|interpro:IPR029289|mint:Q9NQ92|reactome:R-HSA-3214858	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:qO6jrJ2Zx0gVwqXbB+1EtiYvb589606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62318	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-372789|uniprotkb:P43331|uniprotkb:B5BU13|uniprotkb:B4DJP7|ensembl:ENSP00000215829|intact:EBI-10981086	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:smd3_human(display_long)|uniprotkb:SNRPD3(gene name)|psi-mi:SNRPD3(display_short)|uniprotkb:snRNP core protein D3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004166.1|refseq:NP_001265585.1|ensembl:ENSG00000100028(gene)|ensembl:ENST00000215829(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|mint:P62318|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|rcsb pdb:7ABG|rcsb pdb:3VRI|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:3PGW|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|dip:DIP-31216N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:WkrSZVfVmSQrJYfy7mwp48xjsVA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P51991	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q16540	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1046141|uniprotkb:A8MT29|uniprotkb:Q96Q71|ensembl:ENSP00000370930|ensembl:ENSP00000380466|ensembl:ENSP00000500123|ensembl:ENSP00000500896	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rm23_human(display_long)|uniprotkb:L23 mitochondrial-related protein(gene name synonym)|uniprotkb:Ribosomal protein L23-like(gene name synonym)|uniprotkb:L23MRP(gene name synonym)|uniprotkb:RPL23L(gene name synonym)|uniprotkb:MRPL23(gene name)|psi-mi:MRPL23(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL23m(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_066957.3|ensembl:ENSG00000214026(gene)|ensembl:ENSG00000288141(gene)|ensembl:ENST00000381519(transcript)|ensembl:ENST00000397298(transcript)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|ensembl:ENST00000672185(transcript)|ensembl:ENST00000672523(transcript)|go:"GO:0001650"(fibrillar center)|rcsb pdb:7ODS|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|mint:Q16540|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:7ODT|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF0	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:1TSlowXDlWVOW2PS1vv8Lu/e1vU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62277	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351850|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|uniprotkb:Q498Y0|uniprotkb:B2R549|ensembl:ENSP00000435777	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs13_human(display_long)|uniprotkb:RPS13(gene name)|psi-mi:RPS13(display_short)|uniprotkb:Small ribosomal subunit protein uS15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001008.1|ensembl:ENSG00000110700(gene)|ensembl:ENST00000525634(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62277|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6OM7|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62263	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352783|ensembl:ENSP00000311028|ensembl:ENSP00000385425|uniprotkb:P06366|uniprotkb:Q5BJI0|uniprotkb:B2R5G5|uniprotkb:D3DQG5|ensembl:ENSP00000385958|ensembl:ENSP00000428509	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs14_human(display_long)|uniprotkb:RPS14(gene name)|psi-mi:RPS14(display_short)|uniprotkb:Small ribosomal subunit protein uS11(gene name synonym)|uniprotkb:PRO2640(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000164587(gene)|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001020242.1|refseq:NP_005608.1|refseq:NP_001020241.1|ensembl:ENST00000312037(transcript)|ensembl:ENST00000401695(transcript)|ensembl:ENST00000407193(transcript)|ensembl:ENST00000521466(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P62263|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ee3bJ5JYFaZXyCCRG9Wooopyz2o9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P63220	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-714051|uniprotkb:P35265|ensembl:ENSP00000345957	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs21_human(display_long)|uniprotkb:RPS21(gene name)|psi-mi:RPS21(display_short)|uniprotkb:Small ribosomal subunit protein eS21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000171858(gene)|ensembl:ENST00000343986(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000461"("endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001015.1|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR001931(Ribosomal protein S21e)|interpro:IPR018279|interpro:IPR038579|mint:P63220|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6ZMO|rcsb pdb:6G5H|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:7K5I|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3gi91+fAL7ogzcoJlVEaN4D+87A9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P07996	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2530274|uniprotkb:A8K6H4|uniprotkb:B9EGH6|uniprotkb:Q15667|ensembl:ENSP00000260356|uniprotkb:B4E3J7|uniprotkb:Q59E99	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tsp1_human(display_long)|uniprotkb:THBS1(gene name)|psi-mi:THBS1(display_short)|uniprotkb:TSP(gene name synonym)|uniprotkb:TSP1(gene name synonym)|uniprotkb:Glycoprotein G(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000137801(gene)|ensembl:ENST00000260356(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002581"(negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0002605"(negative regulation of dendritic cell antigen processing and presentation)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007155"(cell adhesion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030141"(secretory granule)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032570"(response to progesterone)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0008201"(heparin binding)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0033574"(response to testosterone)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070052"(collagen V binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR028499|interpro:IPR028974|interpro:IPR036383|mint:P07996|rcsb pdb:1LSL|rcsb pdb:1UX6|rcsb pdb:1Z78|rcsb pdb:1ZA4|rcsb pdb:2ERF|rcsb pdb:2ES3|rcsb pdb:2OUH|rcsb pdb:2OUJ|rcsb pdb:3R6B|rcsb pdb:5FOE|reactome:R-HSA-114608|reactome:R-HSA-186797|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-5083635|reactome:R-HSA-5173214|reactome:R-HSA-8936459|refseq:NP_003237.2|dip:DIP-1037N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wqgWk4yWvhfEjrD+H6BdJrJgVgg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P04350	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BVA1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_821080.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|ensembl:ENST00000259818(transcript)|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-5663220|ensembl:ENSG00000137285(gene)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:sluQMryNuOvp6xlV558+agiRwvE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q71U36	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BWJ5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2555428|uniprotkb:Q7RTV1|uniprotkb:B2R568|ensembl:ENSP00000356541	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sf3b5_human(display_long)|uniprotkb:SF3B10(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 10 kDa subunit(gene name synonym)|uniprotkb:SF3B5(gene name)|psi-mi:SF3B5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_112577.1|ensembl:ENSG00000169976(gene)|ensembl:ENST00000367569(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR009846(Splicing factor 3B subunit 5/RDS3 complex subunit 10)|interpro:IPR017089(Splicing factor 3B, subunit 5)|mint:Q9BWJ5|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5Z57	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wuQBsSytGhSg64IQSmEJXe+26zQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P05114	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q30KQ2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-14061677	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:db130_human(display_long)|uniprotkb:DEFB130(gene name)|psi-mi:DEFB130(display_short)|uniprotkb:DEFB30(gene name synonym)|uniprotkb:DEFB130L(gene name)|psi-mi:DEFB130L(display_short)|uniprotkb:Beta-defensin 30(gene name synonym)|uniprotkb:Defensin, beta 130(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001032893.1|refseq:NP_001182186.1|ensembl:ENST00000400079|ensembl:ENSP00000382951|ensembl:ENSG00000232948|reactome:R-HSA-1461957|reactome:R-HSA-1461973|go:"GO:0005576"(extracellular region)|go:"GO:0042742"(defense response to bacterium)|interpro:IPR001855(Beta defensin)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:bjNXAFgqCmVmpCT8Ft4QlBeIsoE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P51965	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13885	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q12931	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q16769	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2856807|uniprotkb:Q3KRG6|uniprotkb:Q16770|uniprotkb:Q53TR4|ensembl:ENSP00000344829	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:qpct_human(display_long)|uniprotkb:QPCT(gene name)|psi-mi:QPCT(display_short)|uniprotkb:Glutaminyl cyclase(gene name synonym)|uniprotkb:Glutaminyl-tRNA cyclotransferase(gene name synonym)|uniprotkb:Glutamyl cyclase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_036545.1|ensembl:ENSG00000115828(gene)|ensembl:ENST00000338415(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016603"(glutaminyl-peptide cyclotransferase activity)|go:"GO:0017186"(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase)|go:"GO:0035580"(specific granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR007484(Peptidase M28)|interpro:IPR037457|interpro:IPR040234|mint:Q16769|rcsb pdb:1MOI|rcsb pdb:2AFM|rcsb pdb:2AFO|rcsb pdb:2AFS|rcsb pdb:2AFU|rcsb pdb:2AFW|rcsb pdb:2AFX|rcsb pdb:2AFZ|rcsb pdb:2ZED|rcsb pdb:2ZEE|rcsb pdb:2ZEF|rcsb pdb:2ZEG|rcsb pdb:2ZEH|rcsb pdb:2ZEL|rcsb pdb:2ZEM|rcsb pdb:2ZEN|rcsb pdb:2ZEO|rcsb pdb:2ZEP|rcsb pdb:3PBB|rcsb pdb:3PBE|rcsb pdb:3SI0|rcsb pdb:4YU9|rcsb pdb:4YWY|rcsb pdb:6YI1|rcsb pdb:6YJY|rcsb pdb:7COZ|rcsb pdb:7CP0|reactome:R-HSA-6798695|rcsb pdb:6GBX	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:P77dag9F4CgK4eLQHdFlYbz4Kxg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q15029	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-357897|uniprotkb:Q9BUR0|uniprotkb:D3DX58|uniprotkb:B4DK30|ensembl:ENSP00000392094|ensembl:ENSP00000467805|uniprotkb:B4DMC0|uniprotkb:K7EJ81	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:u5s1_human(display_long)|uniprotkb:EFTUD2(gene name)|psi-mi:EFTUD2(display_short)|uniprotkb:KIAA0031(gene name synonym)|uniprotkb:SNRP116(gene name synonym)|uniprotkb:U5 snRNP-specific protein, 116 kDa(gene name synonym)|uniprotkb:Elongation factor Tu GTP-binding domain-containing protein 2(gene name synonym)|uniprotkb:SNU114 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001136077.1|refseq:NP_004238.3|refseq:NP_001245282.1|go:"GO:0042220"(response to cocaine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR041095|interpro:IPR044121|mint:Q15029|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|go:"GO:0035690"|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000108883(gene)|ensembl:ENST00000426333(transcript)|ensembl:ENST00000591382(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030623"(U5 snRNA binding)|refseq:NP_001245283.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/dBQ7TFnGr31AYrb5e215eQ4vfc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P33991	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-374938|uniprotkb:Q8NEH1|uniprotkb:Q99658|ensembl:ENSP00000262105|ensembl:ENSP00000496964	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mcm4_human(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:CDC21(gene name synonym)|uniprotkb:CDC21 homolog(gene name synonym)|uniprotkb:P1-CDC21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005905.2|refseq:NP_877423.1|ensembl:ENSG00000104738(gene)|ensembl:ENST00000262105(transcript)|ensembl:ENST00000649973(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33991|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31729N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:emFkamsHmwBPzoJnPcaL4SaqAlU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P43243	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UJS0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:A6NHR9	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O96019	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O60884	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q14684	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P04843	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P50991	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P68104	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q15365	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75828	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-714504|ensembl:ENSP00000290354|uniprotkb:Q6FHP2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cbr3_human(display_long)|uniprotkb:NADPH-dependent carbonyl reductase 3(gene name synonym)|uniprotkb:CBR3(gene name)|psi-mi:CBR3(display_short)|uniprotkb:Short chain dehydrogenase/reductase family 21C member 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000159231(gene)|ensembl:ENST00000290354(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042376"(phylloquinone catabolic process)|go:"GO:0050890"(cognition)|go:"GO:0070402"(NADPH binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2HRB|reactome:R-HSA-211945|refseq:NP_001227.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:31QYceUdGN2HanRmiei1aR9f8MI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P36542	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62979	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y265	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P08865	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62910	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-438408|ensembl:ENSP00000380156|ensembl:ENSP00000380158|ensembl:ENSP00000388674|ensembl:ENSP00000416429|uniprotkb:P02433|uniprotkb:B2R4Q3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl32_human(display_long)|uniprotkb:RPL32(gene name)|psi-mi:RPL32(display_short)|uniprotkb:Large ribosomal subunit protein eL32(gene name synonym)|uniprotkb:PP9932(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000144713(gene)|ensembl:ENST00000396953(transcript)|ensembl:ENST00000396957(transcript)|ensembl:ENST00000429711(transcript)|ensembl:ENST00000435983(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR001515(Ribosomal protein L32e)|interpro:IPR018263|interpro:IPR036351|mint:P62910|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000985.1|refseq:NP_001007074.1|refseq:NP_001007075.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:8Yhph2ETzWYd07yJcq1cVqsSRjo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q12905	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P35268	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P49458	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-350743|uniprotkb:Q6NVX0|uniprotkb:Q8WTW0|ensembl:ENSP00000305230|uniprotkb:A8K0N0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:srp09_human(display_long)|uniprotkb:SRP9(gene name)|psi-mi:SRP9(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	rcsb pdb:4UYJ|refseq:NP_001123912.1|refseq:NP_003124.1|ensembl:ENSG00000143742(gene)|ensembl:ENST00000304786(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|mint:P49458|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-6151N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Y33fEeeXnma9oF7Fzs6zEGQjVBU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UNE7	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P50402	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P61247	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352378|uniprotkb:P33443|uniprotkb:P49241|uniprotkb:B2R4D4|intact:EBI-3440915|uniprotkb:D3DP05|ensembl:ENSP00000346050	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs3a_human(display_long)|uniprotkb:RPS3A(gene name)|psi-mi:RPS3A(display_short)|uniprotkb:MFTL(gene name synonym)|uniprotkb:FTE1(gene name synonym)|uniprotkb:v-fos transformation effector protein(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000997.1|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:4V6X|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000145425(gene)|ensembl:ENST00000274065(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001593(Ribosomal protein S3Ae)|interpro:IPR018281|interpro:IPR027500|mint:P61247|rcsb pdb:4UG0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6OM7|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-29408N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:g1TMzz8OFWEuhrRCoecj7KW0qTQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62266	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353072|ensembl:ENSP00000296674|ensembl:ENSP00000498621|uniprotkb:P39028|uniprotkb:Q6IB08	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs23_human(display_long)|uniprotkb:RPS23(gene name)|psi-mi:RPS23(display_short)|uniprotkb:Small ribosomal subunit protein uS12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000186468(gene)|ensembl:ENST00000296674(transcript)|ensembl:ENST00000651545(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR005680(Ribosomal protein S23, eukaryotic/archaeal)|interpro:IPR006032(Ribosomal protein S12/S23)|rcsb pdb:5T2C|rcsb pdb:5VYC|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|mint:P62266|rcsb pdb:6G4W|rcsb pdb:4CXG|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:4CXH|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:4UG0|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|refseq:NP_001016.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:MWZPvSL/G45ocaxA5AXKCkDQxNU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P83731	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P61353	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q16891	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P09874	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13263	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P12956	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P06576	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O95831	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O43390	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13310	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O43852	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y230	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P42677	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62847	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354515|uniprotkb:P16632|uniprotkb:Q7Z3D1|uniprotkb:Q5T0P7|uniprotkb:Q5T0P8|uniprotkb:E7EPK6|ensembl:ENSP00000478869	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs24_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short)|uniprotkb:Small ribosomal subunit protein eS24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001135757.1|refseq:NP_001017.1|refseq:NP_001135755.1|refseq:NP_148982.1|ensembl:ENSG00000138326(gene)|ensembl:ENST00000613865(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|mint:P62847|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6XA1|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:M/qkRxabHx9PFaOM7EwKDOOwu7Q9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P16989	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P54105	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-724693|uniprotkb:Q0VDK6|uniprotkb:Q9NRD2|uniprotkb:Q9NRD3|uniprotkb:B2RCS9|ensembl:ENSP00000433919|ensembl:ENSP00000434311	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:icln_human(display_long)|uniprotkb:Chloride conductance regulatory protein ICln(gene name synonym)|uniprotkb:Chloride channel, nucleotide sensitive 1A(gene name synonym)|uniprotkb:Chloride ion current inducer protein(gene name synonym)|uniprotkb:Reticulocyte pICln(gene name synonym)|uniprotkb:CLNS1A(gene name)|psi-mi:CLNS1A(display_short)|uniprotkb:ICLN(gene name synonym)|uniprotkb:CLCI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001284.1|refseq:NP_001298128.1|refseq:NP_001298129.1|refseq:NP_001298130.1|refseq:NP_001298131.1|ensembl:ENSG00000074201(gene)|ensembl:ENST00000525428(transcript)|ensembl:ENST00000528364(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|interpro:IPR003521(Nucleotide-sensitive chloride conductance regulator)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039924|mint:P54105|rcsb pdb:6V0O|reactome:R-HSA-191859|dip:DIP-44185N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:dGx9UwPj9VBp1CiPTRCXnT3IYt89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P09651	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q15942	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13813	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BQG0	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q68CZ1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-5235485|uniprotkb:A0PJ88|uniprotkb:Q9Y2K8|ensembl:ENSP00000493946	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ftm_human(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001121369.1|refseq:NP_056087.2|ensembl:ENSG00000103494(gene)|ensembl:ENST00000647211(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0060039"(pericardium development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|rcsb pdb:2YRB|reactome:R-HSA-5610787|reactome:R-HSA-5620912	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:A1URXcmr5UTNl+5Vov572mFBpdI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9P2R3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:237ungtRc80jqTOKBUnFX9qDUGw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BUJ2	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:IahA7SVR1NmvldrWKQlAwApinQE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q12906	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P98175	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|uniprotkb:A0A0A0MR66|ensembl:ENSP00000366829	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_005667.2|refseq:NP_690595.1|refseq:NP_001191397.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033095|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|ensembl:ENSG00000182872(gene)|ensembl:ENST00000377604(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q14498	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051(gene)|ensembl:ENST00000253363(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|dip:DIP-32928N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P11387	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9Y3F4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-727414|uniprotkb:Q9UQC8|uniprotkb:Q9NTK0|uniprotkb:Q5TZT4|intact:EBI-6190807|uniprotkb:B4DNJ6|uniprotkb:B2R5S5|ensembl:ENSP00000392270	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:strap_human(display_long)|uniprotkb:UNR-interacting protein(gene name synonym)|uniprotkb:WD-40 repeat protein PT-WD(gene name synonym)|uniprotkb:MAP activator with WD repeats(gene name synonym)|uniprotkb:STRAP(gene name)|psi-mi:STRAP(display_short)|uniprotkb:MAWD(gene name synonym)|uniprotkb:UNRIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_009109.3|ensembl:ENSG00000023734(gene)|ensembl:ENST00000419869(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:Q9Y3F4|reactome:R-HSA-2173788	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:/IqZt6BHPxD3S/THUZry4+QUvCE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q14103	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P42167	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-455283|uniprotkb:Q14861|ensembl:ENSP00000450627|uniprotkb:A2T926	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lap2b_human(display_long)|uniprotkb:Thymopoietin-related peptide isoforms beta/gamma(gene name synonym)|uniprotkb:Thymopoietin, isoforms beta/gamma(gene name synonym)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001294904.1|refseq:NP_001027454.1|refseq:NP_001027455.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000556029(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:P42167|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|dip:DIP-43686N|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:S2mYrSugx0Ms4vhw/vYYH/SthOw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P49411	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BWF3	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2856454|uniprotkb:B3KUN0|uniprotkb:Q8WU85|uniprotkb:Q6P1P2|uniprotkb:O02916|uniprotkb:Q4VC48|uniprotkb:B4E1U0|uniprotkb:E7EQS3|ensembl:ENSP00000309166|ensembl:ENSP00000386561|ensembl:ENSP00000386894	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rbm4_human(display_long)|uniprotkb:RBM4(gene name)|psi-mi:RBM4(display_short)|uniprotkb:RBM4A(gene name synonym)|uniprotkb:Lark homolog(gene name synonym)|uniprotkb:RNA-binding motif protein 4(gene name synonym)|uniprotkb:RNA-binding motif protein 4a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001185772.1|refseq:NP_002887.2|refseq:NP_001185773.1|dip:DIP-44199N|ensembl:ENSG00000173933(gene)|ensembl:ENST00000310092(transcript)|ensembl:ENST00000408993(transcript)|ensembl:ENST00000409406(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002190"(cap-independent translational initiation)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:0097167"(circadian regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979|mint:Q9BWF3|rcsb pdb:2DNQ|reactome:R-HSA-400253|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:hbW6dv/AEWQz3mWvA2/9n8h/bbA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P14866	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q15233	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O14818	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P27635	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P24534	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P46782	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551|ensembl:ENSP00000470114|ensembl:ENSP00000472985	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:Small ribosomal subunit protein uS7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001000.2|rcsb pdb:6OLZ|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Z6M|rcsb pdb:6XA1|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6Y0G|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:5FLX|rcsb pdb:6OLG|rcsb pdb:6OLI|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|ensembl:ENSG00000083845(gene)|ensembl:ENST00000196551(transcript)|ensembl:ENST00000596046(transcript)|ensembl:ENST00000601521(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5AJ0|reactome:R-HSA-72702	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62249	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352480|uniprotkb:P17008|uniprotkb:B2RDD5|ensembl:ENSP00000251453	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs16_human(display_long)|uniprotkb:RPS16(gene name)|psi-mi:RPS16(display_short)|uniprotkb:Small ribosomal subunit protein uS9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001011.1|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000105193(gene)|ensembl:ENST00000251453(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62249|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|dip:DIP-33200N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:OrKriR6HsATLaO+drdUa2w3Gpd09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P63244	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96HS1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-713608|uniprotkb:Q96JB0|intact:EBI-2555528|ensembl:ENSP00000438465|uniprotkb:C9IZY7|uniprotkb:A9LN06	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pgam5_human(display_long)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001164014.1|refseq:NP_612642.2|ensembl:ENSG00000247077(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q96HS1|rcsb pdb:3MXO|rcsb pdb:3O0T|rcsb pdb:5MUF|rcsb pdb:6CNI|rcsb pdb:6CNL|reactome:R-HSA-8934903|ensembl:ENST00000498926(transcript)|dip:DIP-50735N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9GZV4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-748028|ensembl:ENSP00000295822|uniprotkb:B2R4V5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:if5a2_human(display_long)|uniprotkb:Eukaryotic initiation factor 5A isoform 2(gene name synonym)|uniprotkb:EIF5A2(gene name)|psi-mi:EIF5A2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0010509"(polyamine homeostasis)|ensembl:ENSG00000163577(gene)|go:"GO:0015031"(protein transport)|go:"GO:0043022"(ribosome binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENST00000295822(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0051028"(mRNA transport)|refseq:NP_065123.1|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|reactome:R-HSA-204626	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:cm95o/2pG+p6gBFemWzLNcMWgt89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62913	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354380|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q8TDH2|uniprotkb:Q9Y674|ensembl:ENSP00000496250	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl11_human(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000966.2|refseq:NP_001186731.1|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62913|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XXB|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y6X	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q06830	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62750	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P60866	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353105|uniprotkb:P17075|uniprotkb:Q5M8S9|uniprotkb:B2R4F4|uniprotkb:B4DW28|ensembl:ENSP00000009589|ensembl:ENSP00000427788|ensembl:ENSP00000503327|ensembl:ENSP00000504123|ensembl:ENSP00000504154|ensembl:ENSP00000504670	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs20_human(display_long)|uniprotkb:RPS20(gene name)|psi-mi:RPS20(display_short)|uniprotkb:Small ribosomal subunit protein uS10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001014.1|refseq:NP_001139699.1|dip:DIP-31245N|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|ensembl:ENSG00000008988(gene)|ensembl:ENST00000009589(transcript)|ensembl:ENST00000521262(transcript)|ensembl:ENST00000676461(transcript)|ensembl:ENST00000676918(transcript)|ensembl:ENST00000678039(transcript)|ensembl:ENST00000678683(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60866|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:6xNxX+eP59AOm0KraCysRHUqMFw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q04837	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BRJ6	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-751612|ensembl:ENSP00000350011|ensembl:ENSP00000380286|ensembl:ENSP00000380288	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cg050_human(display_long)|uniprotkb:FP15621(orf name)|uniprotkb:C7orf50(gene name)|psi-mi:C7orf50(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001127867.1|refseq:NP_001127868.1|refseq:NP_115726.1|refseq:NP_001305181.1|ensembl:ENSG00000146540(gene)|ensembl:ENST00000357429(transcript)|ensembl:ENST00000397098(transcript)|ensembl:ENST00000397100(transcript)|interpro:IPR019327|mint:Q9BRJ6|go:"GO:0003723"(RNA binding)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:POftCOri0Nj8YUd5Kc3nNMDb41A9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P25398	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62304	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8N4Q1	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2562213|uniprotkb:A8K3Z9|uniprotkb:Q96AI2|uniprotkb:Q96MY6|ensembl:ENSP00000380122	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mia40_human(display_long)|uniprotkb:MIA40(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 4(gene name synonym)|uniprotkb:CHCHD4(gene name)|psi-mi:CHCHD4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001091972.1|refseq:NP_653237.1|ensembl:ENSG00000163528(gene)|ensembl:ENST00000396914(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051084"('de novo' posttranslational protein folding)|interpro:IPR010625(CHCH)|interpro:IPR039289|mint:Q8N4Q1|rcsb pdb:2K3J|rcsb pdb:2L0Y|reactome:R-HSA-1268020|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|dip:DIP-48483N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ACH8CTQRjTwq7nz6toGTrn3VHlE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P30050	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:TNPEtl60cILofaPzUznvZiw6D7E9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q99714	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62269	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75533	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-876542|ensembl:ENSP00000335321|uniprotkb:E9PCH3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sf3b1_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0034693"(U11/U12 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015016(Splicing factor 3B subunit 1)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|mint:O75533|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:2PEH|rcsb pdb:3LQV|rcsb pdb:4OZ1|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6N3E|refseq:NP_036565.2|dip:DIP-29411N|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-5250924|reactome:R-HSA-72163|reactome:R-HSA-72165	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P27708	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q16875	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-764464|uniprotkb:Q5VX18|uniprotkb:O43622|uniprotkb:O75902|intact:EBI-2834088|uniprotkb:Q5VX19|uniprotkb:B7Z955|uniprotkb:Q5VX15|ensembl:ENSP00000369100	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:f263_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme(gene name synonym)|uniprotkb:iPFK-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-56(gene name synonym)|uniprotkb:PFKFB3(gene name)|psi-mi:PFKFB3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004557.1|refseq:NP_001269559.1|refseq:NP_001300992.1|dip:DIP-33964N|ensembl:ENSG00000170525(gene)|ensembl:ENST00000379775(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0007420"(brain development)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:2AXN|rcsb pdb:2DWO|rcsb pdb:2DWP|rcsb pdb:2I1V|rcsb pdb:3QPU|rcsb pdb:3QPV|rcsb pdb:3QPW|rcsb pdb:4D4J|rcsb pdb:4D4K|rcsb pdb:4D4L|rcsb pdb:4D4M|rcsb pdb:4MA4|rcsb pdb:5AJV|rcsb pdb:5AJW|rcsb pdb:5AJX|rcsb pdb:5AJY|rcsb pdb:5AJZ|rcsb pdb:5AK0|rcsb pdb:6ETJ|rcsb pdb:6HVH|rcsb pdb:6HVI|rcsb pdb:6HVJ|rcsb pdb:6IBX|rcsb pdb:6IBY|rcsb pdb:6IBZ|rcsb pdb:6IC0|reactome:R-HSA-9634600|interpro:IPR013079(6-phosphofructo-2-kinase)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:BPxZYy35rU3GFHZ0+i9FpfTQh9s9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q08211	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9HDC5	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O15042	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-310697|uniprotkb:A0PJ60|uniprotkb:Q0D2M1|uniprotkb:Q2NKQ7|uniprotkb:Q9BR70|intact:EBI-2555384|ensembl:ENSP00000418563	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sr140_human(display_long)|uniprotkb:KIAA0332(gene name synonym)|uniprotkb:U2SURP(gene name)|psi-mi:U2SURP(display_short)|uniprotkb:140 kDa Ser/Arg-rich domain protein(gene name synonym)|uniprotkb:SR140(gene name synonym)|uniprotkb:U2-associated protein SR140(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001073884.1|refseq:NP_001307148.1|refseq:NP_001307149.1|refseq:NP_001307151.1|ensembl:ENSG00000163714(gene)|ensembl:ENST00000473835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR035009|interpro:IPR035967|interpro:IPR035979|reactome:R-HSA-72163|refseq:XP_016861527.1|refseq:XP_016861528.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:STKTFD8Cu0GQMj+HSpn3qgIEw4c9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P23246	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q8NC51	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P05455	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NYF8	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-437804|ensembl:ENSP00000435210|uniprotkb:Q86WY0|uniprotkb:Q14673|uniprotkb:Q86WU6|uniprotkb:B7ZM58|uniprotkb:A2RU75|uniprotkb:E1P586	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:bclf1_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 1(gene name synonym)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short)|uniprotkb:BTF(gene name synonym)|uniprotkb:KIAA0164(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000029363(gene)|ensembl:ENST00000531224(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR026668|interpro:IPR029199|mint:Q9NYF8|refseq:NP_001070908.1|refseq:NP_001070909.1|refseq:NP_055554.1|refseq:NP_001287967.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:v6qbjyjKVCv0B/olkjQfTPKWqBw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q92841	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62917	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O60506	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P25705	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P46777	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UMS4	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-395746|ensembl:ENSP00000227524	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:prp19_human(display_long)|uniprotkb:PRPF19(gene name)|psi-mi:PRPF19(display_short)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:NMP200(gene name synonym)|uniprotkb:PRP19(gene name synonym)|uniprotkb:SNEV(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000110107(gene)|ensembl:ENST00000227524(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_055317.1|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q9UMS4|rcsb pdb:4LG8|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|dip:DIP-32978N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:5TseaFcCOVVWjJeMF/H7k29nd3c9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P25205	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q02978	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|ensembl:ENSP00000225665|uniprotkb:F5GY65	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_003553.2|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|mint:Q02978|reactome:R-HSA-70263|ensembl:ENSG00000108528(gene)|ensembl:ENST00000225665(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015367"("oxoglutarate:malate antiporter activity")|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96E39	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2211204|ensembl:ENSP00000318415|ensembl:ENSP00000446099|ensembl:ENSP00000498248	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rmxl1_human(display_long)|uniprotkb:RBMXL1(gene name)|psi-mi:RBMXL1(display_short)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G-like 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001156008.1|refseq:NP_062556.2|ensembl:ENSG00000213516(gene)|ensembl:ENST00000321792(transcript)|ensembl:ENST00000399794(transcript)|ensembl:ENST00000652648(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:J2BrUHGcladV+yTecfJVfljlFz89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q96I25	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O95816	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q99848	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P22626	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P14618	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P39023	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P18077	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62701	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62851	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-353054|ensembl:ENSP00000435096|ensembl:ENSP00000486392|uniprotkb:P25111|uniprotkb:B2R4M7	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs25_human(display_long)|uniprotkb:RPS25(gene name)|psi-mi:RPS25(display_short)|uniprotkb:Small ribosomal subunit protein eS25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000118181(gene)|ensembl:ENSG00000280831(gene)|ensembl:ENST00000527673(transcript)|ensembl:ENST00000628770(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004977(Ribosomal protein S25)|interpro:IPR036388|mint:P62851|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y0G|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:6ZXD|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|rcsb pdb:6ZXE|reactome:R-HSA-9010553|reactome:R-HSA-9633012|rcsb pdb:6ZXF|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|refseq:NP_001019.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P15880	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P23396	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9UQ35	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1050142|uniprotkb:A6NKB9|uniprotkb:Q9UHA8|uniprotkb:Q9UQ36|uniprotkb:Q9UQ37|uniprotkb:Q9UQ38|uniprotkb:Q9UQ40|uniprotkb:O15038|uniprotkb:O94803|uniprotkb:Q6NSL3|uniprotkb:Q6PIM3|uniprotkb:Q6PK40|uniprotkb:Q8IW17|uniprotkb:Q96GY7|uniprotkb:Q9P0G1|uniprotkb:D3DU97|ensembl:ENSP00000301740	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:srrm2_human(display_long)|uniprotkb:Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa(gene name synonym)|uniprotkb:Splicing coactivator subunit SRm300(gene name synonym)|uniprotkb:300 kDa nuclear matrix antigen(gene name synonym)|uniprotkb:SRRM2(gene name)|psi-mi:SRRM2(display_short)|uniprotkb:KIAA0324(gene name synonym)|uniprotkb:SRL300(gene name synonym)|uniprotkb:SRM300(gene name synonym)|uniprotkb:HSPC075(orf name)|uniprotkb:Tax-responsive enhancer element-binding protein 803(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_057417.3|ensembl:ENSG00000167978(gene)|ensembl:ENST00000301740(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945|mint:Q9UQ35|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7DVQ|reactome:R-HSA-72163	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:3yyPAOaCzKSCEg5guJSbq0MWrHI9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P27824	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q15393	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62258	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O43143	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q13435	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-749111|uniprotkb:A8K485|uniprotkb:B4DT19|uniprotkb:Q7Z627|uniprotkb:Q969K1|uniprotkb:Q96CM6|uniprotkb:Q9BWD2|intact:EBI-1052093|intact:EBI-2688256|uniprotkb:Q7L4T5|ensembl:ENSP00000318861	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sf3b2_human(display_long)|uniprotkb:SF3B2(gene name)|psi-mi:SF3B2(display_short)|uniprotkb:SAP145(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 145 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 145(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006833.2|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006568(PSP, proline-rich)|ensembl:ENSG00000087365(gene)|ensembl:ENST00000322535(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR007180(Protein of unknown function DUF382)|rcsb pdb:2DO5|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|mint:Q13435|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Y9uCV2x4J5kqyxeO8iXjojkXocA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P12004	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P07910	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P12236	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P52272	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-486809|uniprotkb:Q9Y492|uniprotkb:Q15584|uniprotkb:Q8WZ44|uniprotkb:Q96H56|uniprotkb:Q9BWL9|intact:EBI-28985795|ensembl:ENSP00000325376	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpm_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005959.2|refseq:NP_112480.2|ensembl:ENSG00000099783(gene)|ensembl:ENST00000325495(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:P52272|rcsb pdb:2DGV|rcsb pdb:2DH9|rcsb pdb:2DO0|rcsb pdb:2OT8|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-29336N|ensembl:ENSP00000325376|ensembl:ENST00000348943|ensembl:ENSP00000325732	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:5FnCgrz0xltEkgw3yh70KP2jz5g9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P46778	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-350634|uniprotkb:Q16699|ensembl:ENSP00000346027|ensembl:ENSP00000351021|ensembl:ENSP00000370569|ensembl:ENSP00000370574	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl21_human(display_long)|uniprotkb:RPL21(gene name)|psi-mi:RPL21(display_short)|uniprotkb:Large ribosomal subunit protein eL21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	rcsb pdb:6LU8|refseq:NP_000973.2|ensembl:ENSG00000122026(gene)|ensembl:ENST00000272274(transcript)|ensembl:ENST00000311549(transcript)|ensembl:ENST00000319826(transcript)|ensembl:ENST00000326092(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001147(Ribosomal protein L21e)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018259|interpro:IPR036948|mint:P46778|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6OLE|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:UCth+WL9Oj1Y9I5m4i/9X0a5WHk9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9NR30	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O14654	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P52597	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P46781	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351206|uniprotkb:Q4QRK7|uniprotkb:Q9BVZ0|ensembl:ENSP00000302896|ensembl:ENSP00000375632|ensembl:ENSP00000375633|ensembl:ENSP00000478449|ensembl:ENSP00000479917|ensembl:ENSP00000480135|ensembl:ENSP00000480662|ensembl:ENSP00000481194|ensembl:ENSP00000481553|ensembl:ENSP00000481655|ensembl:ENSP00000481764|ensembl:ENSP00000481822|ensembl:ENSP00000482023|ensembl:ENSP00000482274|ensembl:ENSP00000482338|ensembl:ENSP00000482475|ensembl:ENSP00000483179|ensembl:ENSP00000484394|uniprotkb:A9C4C1	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs9_human(display_long)|uniprotkb:RPS9(gene name)|psi-mi:RPS9(display_short)|uniprotkb:Small ribosomal subunit protein uS4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001004.2|refseq:NP_001308630.1|refseq:NP_001308631.1|refseq:NP_001308633.1|ensembl:ENSG00000170889(gene)|ensembl:ENSG00000274005(gene)|ensembl:ENSG00000274626(gene)|ensembl:ENSG00000274646(gene)|ensembl:ENSG00000274950(gene)|ensembl:ENSG00000275323(gene)|ensembl:ENSG00000277079(gene)|ensembl:ENSG00000277359(gene)|ensembl:ENSG00000278081(gene)|ensembl:ENSG00000278270(gene)|ensembl:ENST00000302907(transcript)|ensembl:ENST00000391752(transcript)|ensembl:ENST00000391753(transcript)|ensembl:ENST00000610826(transcript)|ensembl:ENST00000610953(transcript)|ensembl:ENST00000611921(transcript)|ensembl:ENST00000614737(transcript)|ensembl:ENST00000615346(transcript)|ensembl:ENST00000616082(transcript)|ensembl:ENST00000616536(transcript)|ensembl:ENST00000616839(transcript)|ensembl:ENST00000616877(transcript)|ensembl:ENST00000616928(transcript)|ensembl:ENST00000617291(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000618751(transcript)|go:"GO:0005829"(cytosol)|ensembl:ENST00000619229(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|ensembl:ENST00000620720(transcript)|ensembl:ENST00000620940(transcript)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|mint:P46781|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|go:"GO:0005634"(nucleus)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|go:"GO:0005654"(nucleoplasm)|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P46776	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-350581|uniprotkb:B2R4B3|ensembl:ENSP00000346015	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl27a_human(display_long)|uniprotkb:RPL27A(gene name)|psi-mi:RPL27A(display_short)|uniprotkb:Large ribosomal subunit protein uL15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000981.1|ensembl:ENSG00000166441(gene)|ensembl:ENST00000314138(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001196(Ribosomal protein L15)|interpro:IPR021131|interpro:IPR027386|interpro:IPR030878|interpro:IPR036227|mint:P46776|rcsb pdb:4BXF|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6IP6|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6OM7|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:6IP5|dip:DIP-33121N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tUezMQBw+SWmLYq8M0pkLCF8vO89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P31943	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P18124	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P46821	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62714	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P62906	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P68371	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P61313	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P38646	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P08238	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:O75688	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1047039|uniprotkb:Q9HAY8|uniprotkb:Q461Q2|uniprotkb:Q658R4|ensembl:ENSP00000282412|uniprotkb:Q96ER6|uniprotkb:Q4J6C1|uniprotkb:Q4J6C2	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ppm1b_human(display_long)|uniprotkb:Protein phosphatase 2C isoform beta(gene name synonym)|uniprotkb:PPM1B(gene name)|psi-mi:PPM1B(display_short)|uniprotkb:PP2CB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001028729.1|refseq:NP_002697.1|refseq:NP_808907.1|refseq:NP_808908.1|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR012911(Protein serine/threonine phosphatase 2C, C-terminal)|interpro:IPR036457|interpro:IPR036580|mint:O75688|rcsb pdb:2P8E|reactome:R-HSA-1169408|ensembl:ENSG00000138032(gene)|ensembl:ENST00000282412(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0016020"(membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:cwwfGSSTv9pR/XNLa9UxQ/6hpD89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P07900	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P68363	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P63267	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q99848	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:P05451	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-20721755|uniprotkb:P11379|uniprotkb:Q4ZG28|ensembl:ENSP00000233735	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:reg1a_human(display_long)|uniprotkb:Islet cells regeneration factor(gene name synonym)|uniprotkb:Islet of Langerhans regenerating protein(gene name synonym)|uniprotkb:Pancreatic stone protein(gene name synonym)|uniprotkb:Pancreatic thread protein(gene name synonym)|uniprotkb:Regenerating islet-derived protein 1-alpha(gene name synonym)|uniprotkb:Regenerating protein I alpha(gene name synonym)|uniprotkb:REG1A(gene name)|psi-mi:REG1A(display_short)|uniprotkb:PSPS(gene name synonym)|uniprotkb:PSPS1(gene name synonym)|uniprotkb:REG(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_002900.2|ensembl:ENSG00000115386(gene)|ensembl:ENST00000233735(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007494"(midgut development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030426"(growth cone)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044278"(cell wall disruption in another organism)|go:"GO:0045178"(basal part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904692"(positive regulation of type B pancreatic cell proliferation)|go:"GO:1904699"(positive regulation of acinar cell proliferation)|go:"GO:1990785"(response to water-immersion restraint stress)|go:"GO:1990798"(pancreas regeneration)|go:"GO:1990864"(response to growth hormone-releasing hormone)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:1990878"(cellular response to gastrin)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|rcsb pdb:1LIT|rcsb pdb:1QDD|go:"GO:1903492"(response to acetylsalicylate)	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:0h2zhfJkqxiV6X3K/+Jtioo549I9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-1	uniprotkb:Q9BV47	intact:EBI-20829359|ensembl:ENSP00000233027	intact:EBI-2924519|uniprotkb:Q9BTW0|uniprotkb:D3DSV8|ensembl:ENSP00000256261|ensembl:ENSP00000429176	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dus26_human(display_long)|uniprotkb:DUSP26(gene name)|psi-mi:DUSP26(display_short)|uniprotkb:DUSP24(gene name synonym)|uniprotkb:LDP4(gene name synonym)|uniprotkb:MKP8(gene name synonym)|uniprotkb:NATA1(gene name synonym)|uniprotkb:SKRP3(gene name synonym)|uniprotkb:Low-molecular-mass dual-specificity phosphatase 4(gene name synonym)|uniprotkb:Mitogen-activated protein kinase phosphatase 8(gene name synonym)|uniprotkb:Novel amplified gene in thyroid anaplastic cancer(gene name synonym)|uniprotkb:Dual specificity phosphatase SKRP3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20721387|imex:IM-26491-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	refseq:NP_001292044.1|refseq:NP_001292045.1|refseq:NP_076930.1|ensembl:ENSG00000133878(gene)|ensembl:ENST00000256261(transcript)|ensembl:ENST00000523956(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0004647"|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1902310"(positive regulation of peptidyl-serine dephosphorylation)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020405|interpro:IPR020422|interpro:IPR029021|mint:Q9BV47|rcsb pdb:2E0T|rcsb pdb:4B04|rcsb pdb:4HRF|rcsb pdb:5GTJ	-	-	-	figure legend:st1 f1d|comment:The proteins corresponding to the uniprot IDs Q5SRD3, Q3BBW0, A8MT82, Q6ZNL0, A6NDJ8, provided by authors in supplementary figures 1, were not included because they are obsolete.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2020/12/11	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rogid:6pId8Ttfvp3g5qFNGtjgsvpjl1g9606	rigid:9ClQLf0x6ZzjXYYFPWynPuvmDJA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9NR64	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-6426228|ensembl:ENSP00000367075|uniprotkb:Q9P238|uniprotkb:Q9NR65|uniprotkb:Q9H4X4|uniprotkb:Q5VZ64|uniprotkb:A8K5X0	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:klhl1_human(display_long)|uniprotkb:KLHL1(gene name)|psi-mi:KLHL1(display_short)|uniprotkb:KIAA1490(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0043025"(neuronal cell body)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|go:"GO:0030425"(dendrite)|ensembl:ENSG00000150361(gene)|ensembl:ENST00000377844(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007628"(adult walking behavior)|go:"GO:0016358"(dendrite development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_001273654.1|refseq:NP_065917.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Gp9F8Tdw0CwwDBqqhxae+RIDNfc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9BRS2	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-7307838|intact:MINT-1630868|uniprotkb:Q96NV9|uniprotkb:B2RB28|uniprotkb:Q8NDC8|ensembl:ENSP00000369162	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:riok1_human(display_long)|uniprotkb:RIOK1(gene name)|psi-mi:RIOK1(display_short)|uniprotkb:RIO kinase 1(gene name synonym)|uniprotkb:RIO1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_113668.2|ensembl:ENSG00000124784(gene)|ensembl:ENST00000379834(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034708"(methyltransferase complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000687(RIO kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017407(Serine/threonine-protein kinase Rio1)|interpro:IPR018935|rcsb pdb:4OTP|rcsb pdb:6G5I|rcsb pdb:6V0N|rcsb pdb:6ZV6|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|reactome:R-HSA-6791226	-	isoform-comment:No experimental confirmation available.	comment:mint|comment:homomint	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:1Da5yQeq0zHVuRviiNdxy8/3TqI9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P78527	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P35579	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q10570	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q01804	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1054396|uniprotkb:Q147U2|uniprotkb:Q1ZYK1|uniprotkb:Q6PG39|uniprotkb:Q96MQ5|uniprotkb:Q9NT94|uniprotkb:Q9UPV6|uniprotkb:B4DYS4|ensembl:ENSP00000395487	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:otud4_human(display_long)|uniprotkb:HIN-1(gene name synonym)|uniprotkb:HIV-1-induced protein HIN-1(gene name synonym)|uniprotkb:OTUD4(gene name)|psi-mi:OTUD4(display_short)|uniprotkb:KIAA1046(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:XP_005263136.1|refseq:NP_001096123.1|refseq:NP_059963.1|ensembl:ENSG00000164164(gene)|ensembl:ENST00000447906(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1903093"(regulation of protein K48-linked deubiquitination)|go:"GO:2000660"(negative regulation of interleukin-1-mediated signaling pathway)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR038765	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:humMGfho0HKWE4zhO7+G00gIJfc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9UHB6	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-351479|uniprotkb:Q2TAN7|uniprotkb:Q9BVF2|uniprotkb:Q9H8J1|uniprotkb:Q9HBN5|uniprotkb:Q9NX96|uniprotkb:Q9NXC3|uniprotkb:Q9NXU6|uniprotkb:Q9P0H8|uniprotkb:Q9UHB5|uniprotkb:B2RB09|ensembl:ENSP00000340184|uniprotkb:Q59FE8	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lima1_human(display_long)|uniprotkb:PP624(orf name)|uniprotkb:LIMA1(gene name)|psi-mi:LIMA1(display_short)|uniprotkb:SREBP3(gene name synonym)|uniprotkb:Epithelial protein lost in neoplasm(gene name synonym)|uniprotkb:EPLIN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001107018.1|refseq:NP_001107019.1|refseq:NP_057441.1|refseq:XP_011536757.1|ensembl:ENSG00000050405(gene)|ensembl:ENST00000341247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031526"(brush border membrane)|go:"GO:0031529"(ruffle organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028740|mint:Q9UHB6|rcsb pdb:2D8Y|refseq:NP_001230704.1|refseq:XP_016874919.1|dip:DIP-29633N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:sHqhe21LVzLJXgDMH6IcWukKNHE9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q14974	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q99459	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:ZNRraJHn//46wKLSx7xtZju/lr09606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O60568	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-741582|uniprotkb:Q540C3|ensembl:ENSP00000223127|uniprotkb:B2R6W6	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:plod3_human(display_long)|uniprotkb:PLOD3(gene name)|psi-mi:PLOD3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000106397(gene)|ensembl:ENST00000223127(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005506"(iron ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0008104"(protein localization)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0021915"(neural tube development)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033823"(procollagen glucosyltransferase activity)|go:"GO:0042311"(vasodilation)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O60568|rcsb pdb:6FXK|rcsb pdb:6FXM|rcsb pdb:6FXR|rcsb pdb:6FXT|rcsb pdb:6FXX|rcsb pdb:6FXY|rcsb pdb:6TE3|rcsb pdb:6TEC|refseq:NP_001075.1|rcsb pdb:6TES|rcsb pdb:6TEU|rcsb pdb:6TEX|rcsb pdb:6TEZ|reactome:R-HSA-1650814|rcsb pdb:6WFV	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:dvfk+ko7squrB6c4AayW+fR8EnE9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q8N163	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9Y6U3	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-350454|uniprotkb:Q8NBZ6|uniprotkb:Q8WU97|uniprotkb:Q96JC7|uniprotkb:Q96PY2|ensembl:ENSP00000297029|uniprotkb:A8K2U8	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:adsv_human(display_long)|uniprotkb:SCIN(gene name)|psi-mi:SCIN(display_short)|uniprotkb:Scinderin(gene name synonym)|uniprotkb:KIAA1905(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001106177.1|refseq:NP_149119.1|ensembl:ENSG00000006747(gene)|ensembl:ENST00000297029(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030054"(cell junction)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030012|interpro:IPR036180|rcsb pdb:3FG6|rcsb pdb:5A1K|rcsb pdb:5A1M	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:cWwjpWEbTWVkRADzNSjIFPt6d+g9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q96SB4	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-539478|uniprotkb:Q12890|uniprotkb:Q5R364|uniprotkb:Q5R365|uniprotkb:Q8IY12|uniprotkb:B4DS61|ensembl:ENSP00000362931	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:srpk1_human(display_long)|uniprotkb:Serine/arginine-rich protein-specific kinase 1(gene name synonym)|uniprotkb:SFRS protein kinase 1(gene name synonym)|uniprotkb:SRPK1(gene name)|psi-mi:SRPK1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_003128.3|ensembl:ENSG00000096063(gene)|ensembl:ENST00000373825(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q96SB4|rcsb pdb:1WAK|rcsb pdb:1WBP|rcsb pdb:3BEG|rcsb pdb:4WUA|rcsb pdb:5MXX|rcsb pdb:5MY8|rcsb pdb:5NNG|rcsb pdb:5XV7|rcsb pdb:6FAD|rcsb pdb:7DD1|dip:DIP-33888N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:e335v+Im7IjFP1CdFzPefvU8iQo9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O00567	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q16630	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_008938.2|refseq:NP_001287876.1|ensembl:ENSG00000111605(gene)|ensembl:ENST00000435070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042382"(paraspeckles)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990448"(exon-exon junction complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|reactome:R-HSA-1839117|reactome:R-HSA-5655302|dip:DIP-34501N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P48643	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O00391	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-3920904|uniprotkb:Q8TDL6|uniprotkb:Q8WVP4|uniprotkb:Q5T2X0|uniprotkb:Q59G29|ensembl:ENSP00000356574	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:qsox1_human(display_long)|uniprotkb:QSOX1(gene name)|psi-mi:QSOX1(display_short)|uniprotkb:QSCN6(gene name synonym)|uniprotkb:Quiescin Q6(gene name synonym)|uniprotkb:UNQ2520/PRO6013(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001004128.1|refseq:NP_002817.2|ensembl:ENSG00000116260(gene)|ensembl:ENST00000367602(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006457"(protein folding)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071949"(FAD binding)|go:"GO:0085029"(extracellular matrix assembly)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017905|interpro:IPR036249|interpro:IPR036774|interpro:IPR039798|interpro:IPR040986|interpro:IPR041269|interpro:IPR042568|mint:O00391|rcsb pdb:3LLI|rcsb pdb:3LLK|rcsb pdb:3Q6O|rcsb pdb:4IJ3|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-6798695|reactome:R-HSA-8957275	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:F7LxFmHYOzyu51/r0FQHYzQeUbU9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O43318	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0008349"(MAP kinase kinase kinase kinase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|ensembl:ENSG00000135341(gene)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|ensembl:ENST00000369329(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017421(Mitogen-activated protein kinase kinase kinase 7)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27523N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q92945	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_003676.2|ensembl:ENSG00000088247(gene)|ensembl:ENST00000398148(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:hlybJllTqSgPgtwwz3kc12zDYh49606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P03956	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-3918662|ensembl:ENSP00000322788|uniprotkb:P08156	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mmp1_human(display_long)|uniprotkb:MMP1(gene name)|psi-mi:MMP1(display_short)|uniprotkb:CLG(gene name synonym)|uniprotkb:Fibroblast collagenase(gene name synonym)|uniprotkb:Matrix metalloproteinase-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_002412.1|ensembl:ENSG00000196611(gene)|ensembl:ENST00000315274(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0071492"(cellular response to UV-A)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|rcsb pdb:1AYK|rcsb pdb:1CGE|rcsb pdb:1CGF|rcsb pdb:1CGL|rcsb pdb:1SU3|rcsb pdb:2AYK|rcsb pdb:2CLT|rcsb pdb:2J0T|rcsb pdb:2TCL|rcsb pdb:3AYK|rcsb pdb:3SHI|rcsb pdb:4AUO|rcsb pdb:4AYK|rcsb pdb:966C|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-210991|reactome:R-HSA-381426|reactome:R-HSA-6785807|rcsb pdb:1HFC|dip:DIP-529N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:fjVMrgboHG7G0fDa/a2PNa47fHM9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P52209	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-372761|uniprotkb:Q9BWD8|intact:EBI-11020895|uniprotkb:A8K2Y9|ensembl:ENSP00000270776|uniprotkb:B4DQJ8	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:6pgd_human(display_long)|uniprotkb:PGD(gene name)|psi-mi:PGD(display_short)|uniprotkb:PGDH(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001291380.1|refseq:NP_001291381.1|refseq:NP_002622.2|ensembl:ENSG00000142657(gene)|ensembl:ENST00000270776(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|mint:P52209|rcsb pdb:2JKV|rcsb pdb:4GWG|rcsb pdb:4GWK|rcsb pdb:5UQ9|reactome:R-HSA-71336|interpro:IPR036291	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:SgbOgCLmdWm3QnN6fQfkHG6iunw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q15366	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q15717	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P06733	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P29692	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-358607|uniprotkb:Q969J1|uniprotkb:D3DWK3|intact:EBI-748782|uniprotkb:Q96I38|ensembl:ENSP00000317399|ensembl:ENSP00000378551|ensembl:ENSP00000388261|ensembl:ENSP00000433412|ensembl:ENSP00000433611|ensembl:ENSP00000434448|ensembl:ENSP00000434872|ensembl:ENSP00000436542|ensembl:ENSP00000436933|ensembl:ENSP00000478340|ensembl:ENSP00000479653|ensembl:ENSP00000483527|ensembl:ENSP00000487680|intact:EBI-11048966|uniprotkb:Q4VBZ6|uniprotkb:B4DDU4|uniprotkb:E9PBQ9	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ef1d_human(display_long)|uniprotkb:EEF1D(gene name)|psi-mi:EEF1D(display_short)|uniprotkb:EF1D(gene name synonym)|uniprotkb:Antigen NY-CO-4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001123528.1|refseq:NP_001123527.1|refseq:NP_001123529.1|refseq:NP_001951.2|refseq:XP_011515207.1|refseq:XP_011515208.1|ensembl:ENST00000419152(transcript)|ensembl:ENST00000529272(transcript)|ensembl:ENST00000530191(transcript)|ensembl:ENST00000530445(transcript)|ensembl:ENST00000531218(transcript)|ensembl:ENST00000533494(transcript)|ensembl:ENST00000534380(transcript)|ensembl:ENST00000614575(transcript)|ensembl:ENST00000615067(transcript)|ensembl:ENST00000615698(transcript)|ensembl:ENST00000632587(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0009299"(mRNA transcription)|go:"GO:0010941"(regulation of cell death)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|mint:P29692|rcsb pdb:2MVM|rcsb pdb:2MVN|rcsb pdb:2N51|rcsb pdb:5JPO|reactome:R-HSA-156842|ensembl:ENSG00000104529(gene)|ensembl:ENSG00000273594(gene)|ensembl:ENST00000317198(transcript)|ensembl:ENST00000395119(transcript)|refseq:NP_001304672.1|refseq:NP_001182132.1|refseq:NP_001276879.1|refseq:XP_006716585.1|refseq:XP_006716586.1|refseq:XP_006716587.1|refseq:XP_006716588.1|refseq:XP_005250880.1|refseq:NP_001317575.1|refseq:XP_016868659.1|refseq:NP_001123525.2|refseq:NP_115754.3	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:9Mzpfofeg2W/GQ/JfjFxcCFJnKg9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P36873	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-356283|ensembl:ENSP00000335084	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P61163	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-774234|uniprotkb:P42024|uniprotkb:B2R6B0|ensembl:ENSP00000358921	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:actz_human(display_long)|uniprotkb:Centrosome-associated actin homolog(gene name synonym)|uniprotkb:Actin-RPV(gene name synonym)|uniprotkb:ARP1(gene name synonym)|uniprotkb:ACTR1A(gene name)|psi-mi:ACTR1A(display_short)|uniprotkb:CTRN1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_005727.1|ensembl:ENSG00000138107(gene)|ensembl:ENST00000369905(transcript)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P61163|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:aJHKOSj1qmZ7Pk8aZAyWWd8DEdw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q8WWY3	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1567797|uniprotkb:Q8N7F9|uniprotkb:Q9H271|uniprotkb:Q9Y439|uniprotkb:Q17RB4|intact:EBI-10177194|uniprotkb:F1T0A5|uniprotkb:E7ESA8|uniprotkb:F1T0A4|ensembl:ENSP00000324122|ensembl:ENSP00000483929	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:prp31_human(display_long)|uniprotkb:Pre-mRNA-processing factor 31(gene name synonym)|uniprotkb:U4/U6 snRNP 61 kDa protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-99(gene name synonym)|uniprotkb:PRPF31(gene name)|psi-mi:PRPF31(display_short)|uniprotkb:PRP31(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:XP_006723200.1|refseq:NP_056444.3|ensembl:ENSG00000105618(gene)|ensembl:ENSG00000275885(gene)|ensembl:ENST00000321030(transcript)|ensembl:ENST00000613693(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005690"(U4atac snRNP)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR012976(NOSIC)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070990"(snRNP binding)|interpro:IPR019175|interpro:IPR027105|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071166"(ribonucleoprotein complex localization)|interpro:IPR036070|interpro:IPR042239|mint:Q8WWY3|rcsb pdb:2OZB|rcsb pdb:3JCR|rcsb pdb:3SIU|rcsb pdb:3SIV|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:NsXY3tY7Y2EEK8rxoisqlfpzuf89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q8N954	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-2555378|uniprotkb:B7Z2G4|uniprotkb:A8K0D9|uniprotkb:B8ZZ44|ensembl:ENSP00000386772|uniprotkb:A0A0A0MSF9	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:gpt11_human(display_long)|uniprotkb:GPATCH11(gene name)|psi-mi:GPATCH11(display_short)|uniprotkb:CCDC75(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 75(gene name synonym)|uniprotkb:CENP-Y(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000152133(gene)|ensembl:ENST00000409774(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003676"(nucleic acid binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR025239|interpro:IPR039249|mint:Q8N954|refseq:NP_001309178.1|refseq:NP_001265434.1|refseq:NP_777591.3|refseq:XP_016859237.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:SGJyGylFtt7YkAqS1DRW5y3Yo089606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q07955	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P25789	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-359310|uniprotkb:Q8TBD1|uniprotkb:Q53XP2|ensembl:ENSP00000044462|ensembl:ENSP00000453887|uniprotkb:D3DW86|uniprotkb:Q567Q5	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:psa4_human(display_long)|uniprotkb:PSMA4(gene name)|psi-mi:PSMA4(display_short)|uniprotkb:PSC9(gene name synonym)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:HC9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001096137.1|refseq:NP_002780.1|rcsb pdb:6XMJ|reactome:R-HSA-2467813|reactome:R-HSA-2871837|rcsb pdb:7AWE|reactome:R-HSA-349425|reactome:R-HSA-1169091|reactome:R-HSA-350562|reactome:R-HSA-1234176|reactome:R-HSA-382556|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-450408|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5358346|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000041357(gene)|ensembl:ENST00000044462(transcript)|ensembl:ENST00000559082(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:P25789|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|refseq:NP_001096138.1|refseq:NP_001317605.1|dip:DIP-29365N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:u+wKxvIa9JKb4Zu9K+tnY3d26tw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P05451	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-20721755|uniprotkb:P11379|uniprotkb:Q4ZG28|ensembl:ENSP00000233735	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:reg1a_human(display_long)|uniprotkb:Islet cells regeneration factor(gene name synonym)|uniprotkb:Islet of Langerhans regenerating protein(gene name synonym)|uniprotkb:Pancreatic stone protein(gene name synonym)|uniprotkb:Pancreatic thread protein(gene name synonym)|uniprotkb:Regenerating islet-derived protein 1-alpha(gene name synonym)|uniprotkb:Regenerating protein I alpha(gene name synonym)|uniprotkb:REG1A(gene name)|psi-mi:REG1A(display_short)|uniprotkb:PSPS(gene name synonym)|uniprotkb:PSPS1(gene name synonym)|uniprotkb:REG(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_002900.2|ensembl:ENSG00000115386(gene)|ensembl:ENST00000233735(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007494"(midgut development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030426"(growth cone)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044278"(cell wall disruption in another organism)|go:"GO:0045178"(basal part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904692"(positive regulation of type B pancreatic cell proliferation)|go:"GO:1904699"(positive regulation of acinar cell proliferation)|go:"GO:1990785"(response to water-immersion restraint stress)|go:"GO:1990798"(pancreas regeneration)|go:"GO:1990864"(response to growth hormone-releasing hormone)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:1990878"(cellular response to gastrin)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|rcsb pdb:1LIT|rcsb pdb:1QDD|go:"GO:1903492"(response to acetylsalicylate)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:0h2zhfJkqxiV6X3K/+Jtioo549I9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q09028	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P19105	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-354418|uniprotkb:Q53X45|ensembl:ENSP00000217652|ensembl:ENSP00000441231|ensembl:ENSP00000462171|ensembl:ENSP00000463614	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ml12a_human(display_long)|uniprotkb:MYL12A(gene name)|psi-mi:MYL12A(display_short)|uniprotkb:RLC(gene name synonym)|uniprotkb:MLCB(gene name synonym)|uniprotkb:Myosin regulatory light chain 2, nonsarcomeric(gene name synonym)|uniprotkb:Myosin RLC(gene name synonym)|uniprotkb:MLC-2B(gene name synonym)|uniprotkb:MRLC3(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC3(gene name synonym)|uniprotkb:Epididymis secretory protein Li 24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_006462.1|refseq:NP_001289976.1|refseq:NP_001289977.1|refseq:NP_001289978.1|ensembl:ENSG00000101608(gene)|ensembl:ENST00000217652(transcript)|ensembl:ENST00000536605(transcript)|ensembl:ENST00000578611(transcript)|ensembl:ENST00000579226(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:P19105|reactome:R-HSA-3928664|reactome:R-HSA-445355	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Q1Uv36YgdA5rMmMOyX5+3rKKho09606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P63104	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q01130	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P60660	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P83881	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1054835|uniprotkb:P09896|uniprotkb:P10661|uniprotkb:Q5J9I6|uniprotkb:Q08ES5|ensembl:ENSP00000446503	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl36a_human(display_long)|uniprotkb:60S ribosomal protein L44(gene name synonym)|uniprotkb:Cell migration-inducing gene 6 protein(gene name synonym)|uniprotkb:RPL36A(gene name)|psi-mi:RPL36A(display_short)|uniprotkb:MIG6(orf name)|uniprotkb:RPL44(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 15 protein(gene name synonym)|uniprotkb:GIG15(orf name)|uniprotkb:Large ribosomal subunit protein eL42(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_066357.2|ensembl:ENSG00000241343(gene)|ensembl:ENST00000553110(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P83881|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:OrRyOEVJZbSdttK93KL/DS5YxJ89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P05386	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62316	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P18859	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-2606700|ensembl:ENSP00000284971|ensembl:ENSP00000382959|ensembl:ENSP00000382962|ensembl:ENSP00000382965|ensembl:ENSP00000382966|uniprotkb:J3KQ83	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:atp5j_human(display_long)|uniprotkb:ATP5PF(gene name)|psi-mi:ATP5PF(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5J(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001003696.1|refseq:NP_001003697.1|refseq:NP_001003701.1|refseq:NP_001003703.1|refseq:NP_001676.2|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P18859|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000154723(gene)|ensembl:ENST00000284971(transcript)|ensembl:ENST00000400087(transcript)|ensembl:ENST00000400090(transcript)|ensembl:ENST00000400093(transcript)|ensembl:ENST00000400094(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|refseq:NP_001307195.1|refseq:NP_001307196.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:0swdCmCT2TBep9+xToVV0Ntl2ZA9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62314	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q15427	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O94905	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9GZS3	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P61981	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P31946	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q6NVV1	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-2880684	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:r13p3_human(display_long)|uniprotkb:RPL13AP3(gene name)|psi-mi:RPL13AP3(display_short)|uniprotkb:60S ribosomal protein L13a pseudogene 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR036899	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:XmYWkWYmWbCrPqmISrFtJ/k+cnI9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P63267	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P16989	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P54105	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-724693|uniprotkb:Q0VDK6|uniprotkb:Q9NRD2|uniprotkb:Q9NRD3|uniprotkb:B2RCS9|ensembl:ENSP00000433919|ensembl:ENSP00000434311	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:icln_human(display_long)|uniprotkb:Chloride conductance regulatory protein ICln(gene name synonym)|uniprotkb:Chloride channel, nucleotide sensitive 1A(gene name synonym)|uniprotkb:Chloride ion current inducer protein(gene name synonym)|uniprotkb:Reticulocyte pICln(gene name synonym)|uniprotkb:CLNS1A(gene name)|psi-mi:CLNS1A(display_short)|uniprotkb:ICLN(gene name synonym)|uniprotkb:CLCI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001284.1|refseq:NP_001298128.1|refseq:NP_001298129.1|refseq:NP_001298130.1|refseq:NP_001298131.1|ensembl:ENSG00000074201(gene)|ensembl:ENST00000525428(transcript)|ensembl:ENST00000528364(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|interpro:IPR003521(Nucleotide-sensitive chloride conductance regulator)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039924|mint:P54105|rcsb pdb:6V0O|reactome:R-HSA-191859|dip:DIP-44185N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:dGx9UwPj9VBp1CiPTRCXnT3IYt89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P09651	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q15942	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q13813	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9BQG0	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q68CZ1	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-5235485|uniprotkb:A0PJ88|uniprotkb:Q9Y2K8|ensembl:ENSP00000493946	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ftm_human(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001121369.1|refseq:NP_056087.2|ensembl:ENSG00000103494(gene)|ensembl:ENST00000647211(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0060039"(pericardium development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|rcsb pdb:2YRB|reactome:R-HSA-5610787|reactome:R-HSA-5620912	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:A1URXcmr5UTNl+5Vov572mFBpdI9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9P2R3	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:237ungtRc80jqTOKBUnFX9qDUGw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9BUJ2	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:IahA7SVR1NmvldrWKQlAwApinQE9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q12906	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P98175	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|uniprotkb:A0A0A0MR66|ensembl:ENSP00000366829	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_005667.2|refseq:NP_690595.1|refseq:NP_001191397.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033095|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|ensembl:ENSG00000182872(gene)|ensembl:ENST00000377604(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q14498	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051(gene)|ensembl:ENST00000253363(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|dip:DIP-32928N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P11387	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9Y3F4	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-727414|uniprotkb:Q9UQC8|uniprotkb:Q9NTK0|uniprotkb:Q5TZT4|intact:EBI-6190807|uniprotkb:B4DNJ6|uniprotkb:B2R5S5|ensembl:ENSP00000392270	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:strap_human(display_long)|uniprotkb:UNR-interacting protein(gene name synonym)|uniprotkb:WD-40 repeat protein PT-WD(gene name synonym)|uniprotkb:MAP activator with WD repeats(gene name synonym)|uniprotkb:STRAP(gene name)|psi-mi:STRAP(display_short)|uniprotkb:MAWD(gene name synonym)|uniprotkb:UNRIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_009109.3|ensembl:ENSG00000023734(gene)|ensembl:ENST00000419869(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:Q9Y3F4|reactome:R-HSA-2173788	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:/IqZt6BHPxD3S/THUZry4+QUvCE9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q14103	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P42167	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-455283|uniprotkb:Q14861|ensembl:ENSP00000450627|uniprotkb:A2T926	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:lap2b_human(display_long)|uniprotkb:Thymopoietin-related peptide isoforms beta/gamma(gene name synonym)|uniprotkb:Thymopoietin, isoforms beta/gamma(gene name synonym)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001294904.1|refseq:NP_001027454.1|refseq:NP_001027455.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000556029(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:P42167|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|dip:DIP-43686N|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:S2mYrSugx0Ms4vhw/vYYH/SthOw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P49411	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9BWF3	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-2856454|uniprotkb:B3KUN0|uniprotkb:Q8WU85|uniprotkb:Q6P1P2|uniprotkb:O02916|uniprotkb:Q4VC48|uniprotkb:B4E1U0|uniprotkb:E7EQS3|ensembl:ENSP00000309166|ensembl:ENSP00000386561|ensembl:ENSP00000386894	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rbm4_human(display_long)|uniprotkb:RBM4(gene name)|psi-mi:RBM4(display_short)|uniprotkb:RBM4A(gene name synonym)|uniprotkb:Lark homolog(gene name synonym)|uniprotkb:RNA-binding motif protein 4(gene name synonym)|uniprotkb:RNA-binding motif protein 4a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001185772.1|refseq:NP_002887.2|refseq:NP_001185773.1|dip:DIP-44199N|ensembl:ENSG00000173933(gene)|ensembl:ENST00000310092(transcript)|ensembl:ENST00000408993(transcript)|ensembl:ENST00000409406(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002190"(cap-independent translational initiation)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:0097167"(circadian regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979|mint:Q9BWF3|rcsb pdb:2DNQ|reactome:R-HSA-400253|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:hbW6dv/AEWQz3mWvA2/9n8h/bbA9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P14866	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q15233	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O14818	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P27635	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P24534	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P46782	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551|ensembl:ENSP00000470114|ensembl:ENSP00000472985	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:Small ribosomal subunit protein uS7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001000.2|rcsb pdb:6OLZ|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Z6M|rcsb pdb:6XA1|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6Y0G|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:5FLX|rcsb pdb:6OLG|rcsb pdb:6OLI|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|ensembl:ENSG00000083845(gene)|ensembl:ENST00000196551(transcript)|ensembl:ENST00000596046(transcript)|ensembl:ENST00000601521(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5AJ0|reactome:R-HSA-72702	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62249	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-352480|uniprotkb:P17008|uniprotkb:B2RDD5|ensembl:ENSP00000251453	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs16_human(display_long)|uniprotkb:RPS16(gene name)|psi-mi:RPS16(display_short)|uniprotkb:Small ribosomal subunit protein uS9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001011.1|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000105193(gene)|ensembl:ENST00000251453(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62249|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|dip:DIP-33200N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:OrKriR6HsATLaO+drdUa2w3Gpd09606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P63244	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q96HS1	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-713608|uniprotkb:Q96JB0|intact:EBI-2555528|ensembl:ENSP00000438465|uniprotkb:C9IZY7|uniprotkb:A9LN06	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pgam5_human(display_long)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001164014.1|refseq:NP_612642.2|ensembl:ENSG00000247077(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q96HS1|rcsb pdb:3MXO|rcsb pdb:3O0T|rcsb pdb:5MUF|rcsb pdb:6CNI|rcsb pdb:6CNL|reactome:R-HSA-8934903|ensembl:ENST00000498926(transcript)|dip:DIP-50735N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9GZV4	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-748028|ensembl:ENSP00000295822|uniprotkb:B2R4V5	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:if5a2_human(display_long)|uniprotkb:Eukaryotic initiation factor 5A isoform 2(gene name synonym)|uniprotkb:EIF5A2(gene name)|psi-mi:EIF5A2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0010509"(polyamine homeostasis)|ensembl:ENSG00000163577(gene)|go:"GO:0015031"(protein transport)|go:"GO:0043022"(ribosome binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENST00000295822(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0051028"(mRNA transport)|refseq:NP_065123.1|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|reactome:R-HSA-204626	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:cm95o/2pG+p6gBFemWzLNcMWgt89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62913	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-354380|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q8TDH2|uniprotkb:Q9Y674|ensembl:ENSP00000496250	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl11_human(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_000966.2|refseq:NP_001186731.1|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62913|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XXB|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y6X	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q06830	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62750	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P60866	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-353105|uniprotkb:P17075|uniprotkb:Q5M8S9|uniprotkb:B2R4F4|uniprotkb:B4DW28|ensembl:ENSP00000009589|ensembl:ENSP00000427788|ensembl:ENSP00000503327|ensembl:ENSP00000504123|ensembl:ENSP00000504154|ensembl:ENSP00000504670	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs20_human(display_long)|uniprotkb:RPS20(gene name)|psi-mi:RPS20(display_short)|uniprotkb:Small ribosomal subunit protein uS10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001014.1|refseq:NP_001139699.1|dip:DIP-31245N|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|ensembl:ENSG00000008988(gene)|ensembl:ENST00000009589(transcript)|ensembl:ENST00000521262(transcript)|ensembl:ENST00000676461(transcript)|ensembl:ENST00000676918(transcript)|ensembl:ENST00000678039(transcript)|ensembl:ENST00000678683(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60866|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:6xNxX+eP59AOm0KraCysRHUqMFw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q04837	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9BRJ6	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-751612|ensembl:ENSP00000350011|ensembl:ENSP00000380286|ensembl:ENSP00000380288	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:cg050_human(display_long)|uniprotkb:FP15621(orf name)|uniprotkb:C7orf50(gene name)|psi-mi:C7orf50(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001127867.1|refseq:NP_001127868.1|refseq:NP_115726.1|refseq:NP_001305181.1|ensembl:ENSG00000146540(gene)|ensembl:ENST00000357429(transcript)|ensembl:ENST00000397098(transcript)|ensembl:ENST00000397100(transcript)|interpro:IPR019327|mint:Q9BRJ6|go:"GO:0003723"(RNA binding)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:POftCOri0Nj8YUd5Kc3nNMDb41A9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P25398	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62304	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q8N4Q1	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-2562213|uniprotkb:A8K3Z9|uniprotkb:Q96AI2|uniprotkb:Q96MY6|ensembl:ENSP00000380122	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mia40_human(display_long)|uniprotkb:MIA40(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 4(gene name synonym)|uniprotkb:CHCHD4(gene name)|psi-mi:CHCHD4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001091972.1|refseq:NP_653237.1|ensembl:ENSG00000163528(gene)|ensembl:ENST00000396914(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051084"('de novo' posttranslational protein folding)|interpro:IPR010625(CHCH)|interpro:IPR039289|mint:Q8N4Q1|rcsb pdb:2K3J|rcsb pdb:2L0Y|reactome:R-HSA-1268020|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|dip:DIP-48483N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:ACH8CTQRjTwq7nz6toGTrn3VHlE9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P30050	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:TNPEtl60cILofaPzUznvZiw6D7E9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q99714	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62269	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O75533	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-876542|ensembl:ENSP00000335321|uniprotkb:E9PCH3	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sf3b1_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0034693"(U11/U12 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015016(Splicing factor 3B subunit 1)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|mint:O75533|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:2PEH|rcsb pdb:3LQV|rcsb pdb:4OZ1|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6N3E|refseq:NP_036565.2|dip:DIP-29411N|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-5250924|reactome:R-HSA-72163|reactome:R-HSA-72165	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P27708	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q16875	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-764464|uniprotkb:Q5VX18|uniprotkb:O43622|uniprotkb:O75902|intact:EBI-2834088|uniprotkb:Q5VX19|uniprotkb:B7Z955|uniprotkb:Q5VX15|ensembl:ENSP00000369100	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:f263_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme(gene name synonym)|uniprotkb:iPFK-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-56(gene name synonym)|uniprotkb:PFKFB3(gene name)|psi-mi:PFKFB3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_004557.1|refseq:NP_001269559.1|refseq:NP_001300992.1|dip:DIP-33964N|ensembl:ENSG00000170525(gene)|ensembl:ENST00000379775(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0007420"(brain development)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:2AXN|rcsb pdb:2DWO|rcsb pdb:2DWP|rcsb pdb:2I1V|rcsb pdb:3QPU|rcsb pdb:3QPV|rcsb pdb:3QPW|rcsb pdb:4D4J|rcsb pdb:4D4K|rcsb pdb:4D4L|rcsb pdb:4D4M|rcsb pdb:4MA4|rcsb pdb:5AJV|rcsb pdb:5AJW|rcsb pdb:5AJX|rcsb pdb:5AJY|rcsb pdb:5AJZ|rcsb pdb:5AK0|rcsb pdb:6ETJ|rcsb pdb:6HVH|rcsb pdb:6HVI|rcsb pdb:6HVJ|rcsb pdb:6IBX|rcsb pdb:6IBY|rcsb pdb:6IBZ|rcsb pdb:6IC0|reactome:R-HSA-9634600|interpro:IPR013079(6-phosphofructo-2-kinase)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:BPxZYy35rU3GFHZ0+i9FpfTQh9s9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q08211	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9HDC5	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O15042	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-310697|uniprotkb:A0PJ60|uniprotkb:Q0D2M1|uniprotkb:Q2NKQ7|uniprotkb:Q9BR70|intact:EBI-2555384|ensembl:ENSP00000418563	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sr140_human(display_long)|uniprotkb:KIAA0332(gene name synonym)|uniprotkb:U2SURP(gene name)|psi-mi:U2SURP(display_short)|uniprotkb:140 kDa Ser/Arg-rich domain protein(gene name synonym)|uniprotkb:SR140(gene name synonym)|uniprotkb:U2-associated protein SR140(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001073884.1|refseq:NP_001307148.1|refseq:NP_001307149.1|refseq:NP_001307151.1|ensembl:ENSG00000163714(gene)|ensembl:ENST00000473835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR035009|interpro:IPR035967|interpro:IPR035979|reactome:R-HSA-72163|refseq:XP_016861527.1|refseq:XP_016861528.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:STKTFD8Cu0GQMj+HSpn3qgIEw4c9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P23246	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q8NC51	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P05455	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9NYF8	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-437804|ensembl:ENSP00000435210|uniprotkb:Q86WY0|uniprotkb:Q14673|uniprotkb:Q86WU6|uniprotkb:B7ZM58|uniprotkb:A2RU75|uniprotkb:E1P586	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:bclf1_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 1(gene name synonym)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short)|uniprotkb:BTF(gene name synonym)|uniprotkb:KIAA0164(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000029363(gene)|ensembl:ENST00000531224(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR026668|interpro:IPR029199|mint:Q9NYF8|refseq:NP_001070908.1|refseq:NP_001070909.1|refseq:NP_055554.1|refseq:NP_001287967.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:v6qbjyjKVCv0B/olkjQfTPKWqBw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q92841	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62917	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O60506	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P25705	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P46777	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9UMS4	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-395746|ensembl:ENSP00000227524	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:prp19_human(display_long)|uniprotkb:PRPF19(gene name)|psi-mi:PRPF19(display_short)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:NMP200(gene name synonym)|uniprotkb:PRP19(gene name synonym)|uniprotkb:SNEV(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000110107(gene)|ensembl:ENST00000227524(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_055317.1|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q9UMS4|rcsb pdb:4LG8|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|dip:DIP-32978N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:5TseaFcCOVVWjJeMF/H7k29nd3c9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P25205	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q02978	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|ensembl:ENSP00000225665|uniprotkb:F5GY65	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_003553.2|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|mint:Q02978|reactome:R-HSA-70263|ensembl:ENSG00000108528(gene)|ensembl:ENST00000225665(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015367"("oxoglutarate:malate antiporter activity")|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q96E39	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-2211204|ensembl:ENSP00000318415|ensembl:ENSP00000446099|ensembl:ENSP00000498248	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rmxl1_human(display_long)|uniprotkb:RBMXL1(gene name)|psi-mi:RBMXL1(display_short)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G-like 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001156008.1|refseq:NP_062556.2|ensembl:ENSG00000213516(gene)|ensembl:ENST00000321792(transcript)|ensembl:ENST00000399794(transcript)|ensembl:ENST00000652648(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:J2BrUHGcladV+yTecfJVfljlFz89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q96I25	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O95816	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q99848	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P22626	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P14618	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P39023	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P18077	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62701	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62851	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-353054|ensembl:ENSP00000435096|ensembl:ENSP00000486392|uniprotkb:P25111|uniprotkb:B2R4M7	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs25_human(display_long)|uniprotkb:RPS25(gene name)|psi-mi:RPS25(display_short)|uniprotkb:Small ribosomal subunit protein eS25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000118181(gene)|ensembl:ENSG00000280831(gene)|ensembl:ENST00000527673(transcript)|ensembl:ENST00000628770(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004977(Ribosomal protein S25)|interpro:IPR036388|mint:P62851|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y0G|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:6ZXD|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|rcsb pdb:6ZXE|reactome:R-HSA-9010553|reactome:R-HSA-9633012|rcsb pdb:6ZXF|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|refseq:NP_001019.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P15880	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P23396	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9UQ35	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1050142|uniprotkb:A6NKB9|uniprotkb:Q9UHA8|uniprotkb:Q9UQ36|uniprotkb:Q9UQ37|uniprotkb:Q9UQ38|uniprotkb:Q9UQ40|uniprotkb:O15038|uniprotkb:O94803|uniprotkb:Q6NSL3|uniprotkb:Q6PIM3|uniprotkb:Q6PK40|uniprotkb:Q8IW17|uniprotkb:Q96GY7|uniprotkb:Q9P0G1|uniprotkb:D3DU97|ensembl:ENSP00000301740	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:srrm2_human(display_long)|uniprotkb:Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa(gene name synonym)|uniprotkb:Splicing coactivator subunit SRm300(gene name synonym)|uniprotkb:300 kDa nuclear matrix antigen(gene name synonym)|uniprotkb:SRRM2(gene name)|psi-mi:SRRM2(display_short)|uniprotkb:KIAA0324(gene name synonym)|uniprotkb:SRL300(gene name synonym)|uniprotkb:SRM300(gene name synonym)|uniprotkb:HSPC075(orf name)|uniprotkb:Tax-responsive enhancer element-binding protein 803(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_057417.3|ensembl:ENSG00000167978(gene)|ensembl:ENST00000301740(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945|mint:Q9UQ35|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7DVQ|reactome:R-HSA-72163	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:3yyPAOaCzKSCEg5guJSbq0MWrHI9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P27824	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q15393	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62258	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O43143	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q13435	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-749111|uniprotkb:A8K485|uniprotkb:B4DT19|uniprotkb:Q7Z627|uniprotkb:Q969K1|uniprotkb:Q96CM6|uniprotkb:Q9BWD2|intact:EBI-1052093|intact:EBI-2688256|uniprotkb:Q7L4T5|ensembl:ENSP00000318861	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:sf3b2_human(display_long)|uniprotkb:SF3B2(gene name)|psi-mi:SF3B2(display_short)|uniprotkb:SAP145(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 145 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 145(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_006833.2|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006568(PSP, proline-rich)|ensembl:ENSG00000087365(gene)|ensembl:ENST00000322535(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR007180(Protein of unknown function DUF382)|rcsb pdb:2DO5|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|mint:Q13435|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Y9uCV2x4J5kqyxeO8iXjojkXocA9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P12004	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P07910	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P12236	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P52272	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-486809|uniprotkb:Q9Y492|uniprotkb:Q15584|uniprotkb:Q8WZ44|uniprotkb:Q96H56|uniprotkb:Q9BWL9|intact:EBI-28985795|ensembl:ENSP00000325376	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpm_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_005959.2|refseq:NP_112480.2|ensembl:ENSG00000099783(gene)|ensembl:ENST00000325495(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:P52272|rcsb pdb:2DGV|rcsb pdb:2DH9|rcsb pdb:2DO0|rcsb pdb:2OT8|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-29336N|ensembl:ENSP00000325376|ensembl:ENST00000348943|ensembl:ENSP00000325732	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:5FnCgrz0xltEkgw3yh70KP2jz5g9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P46778	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-350634|uniprotkb:Q16699|ensembl:ENSP00000346027|ensembl:ENSP00000351021|ensembl:ENSP00000370569|ensembl:ENSP00000370574	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl21_human(display_long)|uniprotkb:RPL21(gene name)|psi-mi:RPL21(display_short)|uniprotkb:Large ribosomal subunit protein eL21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	rcsb pdb:6LU8|refseq:NP_000973.2|ensembl:ENSG00000122026(gene)|ensembl:ENST00000272274(transcript)|ensembl:ENST00000311549(transcript)|ensembl:ENST00000319826(transcript)|ensembl:ENST00000326092(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001147(Ribosomal protein L21e)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018259|interpro:IPR036948|mint:P46778|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6OLE|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:UCth+WL9Oj1Y9I5m4i/9X0a5WHk9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:Q9NR30	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O14654	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P52597	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P46781	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-351206|uniprotkb:Q4QRK7|uniprotkb:Q9BVZ0|ensembl:ENSP00000302896|ensembl:ENSP00000375632|ensembl:ENSP00000375633|ensembl:ENSP00000478449|ensembl:ENSP00000479917|ensembl:ENSP00000480135|ensembl:ENSP00000480662|ensembl:ENSP00000481194|ensembl:ENSP00000481553|ensembl:ENSP00000481655|ensembl:ENSP00000481764|ensembl:ENSP00000481822|ensembl:ENSP00000482023|ensembl:ENSP00000482274|ensembl:ENSP00000482338|ensembl:ENSP00000482475|ensembl:ENSP00000483179|ensembl:ENSP00000484394|uniprotkb:A9C4C1	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rs9_human(display_long)|uniprotkb:RPS9(gene name)|psi-mi:RPS9(display_short)|uniprotkb:Small ribosomal subunit protein uS4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001004.2|refseq:NP_001308630.1|refseq:NP_001308631.1|refseq:NP_001308633.1|ensembl:ENSG00000170889(gene)|ensembl:ENSG00000274005(gene)|ensembl:ENSG00000274626(gene)|ensembl:ENSG00000274646(gene)|ensembl:ENSG00000274950(gene)|ensembl:ENSG00000275323(gene)|ensembl:ENSG00000277079(gene)|ensembl:ENSG00000277359(gene)|ensembl:ENSG00000278081(gene)|ensembl:ENSG00000278270(gene)|ensembl:ENST00000302907(transcript)|ensembl:ENST00000391752(transcript)|ensembl:ENST00000391753(transcript)|ensembl:ENST00000610826(transcript)|ensembl:ENST00000610953(transcript)|ensembl:ENST00000611921(transcript)|ensembl:ENST00000614737(transcript)|ensembl:ENST00000615346(transcript)|ensembl:ENST00000616082(transcript)|ensembl:ENST00000616536(transcript)|ensembl:ENST00000616839(transcript)|ensembl:ENST00000616877(transcript)|ensembl:ENST00000616928(transcript)|ensembl:ENST00000617291(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000618751(transcript)|go:"GO:0005829"(cytosol)|ensembl:ENST00000619229(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|ensembl:ENST00000620720(transcript)|ensembl:ENST00000620940(transcript)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|mint:P46781|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|go:"GO:0005634"(nucleus)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|go:"GO:0005654"(nucleoplasm)|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P60709	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P46776	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-350581|uniprotkb:B2R4B3|ensembl:ENSP00000346015	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl27a_human(display_long)|uniprotkb:RPL27A(gene name)|psi-mi:RPL27A(display_short)|uniprotkb:Large ribosomal subunit protein uL15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_000981.1|ensembl:ENSG00000166441(gene)|ensembl:ENST00000314138(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001196(Ribosomal protein L15)|interpro:IPR021131|interpro:IPR027386|interpro:IPR030878|interpro:IPR036227|mint:P46776|rcsb pdb:4BXF|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6IP6|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6OM7|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:6IP5|dip:DIP-33121N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:tUezMQBw+SWmLYq8M0pkLCF8vO89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P31943	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P18124	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P46821	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62714	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P68371	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P61313	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P38646	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P08238	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:O75688	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-1047039|uniprotkb:Q9HAY8|uniprotkb:Q461Q2|uniprotkb:Q658R4|ensembl:ENSP00000282412|uniprotkb:Q96ER6|uniprotkb:Q4J6C1|uniprotkb:Q4J6C2	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:ppm1b_human(display_long)|uniprotkb:Protein phosphatase 2C isoform beta(gene name synonym)|uniprotkb:PPM1B(gene name)|psi-mi:PPM1B(display_short)|uniprotkb:PP2CB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_001028729.1|refseq:NP_002697.1|refseq:NP_808907.1|refseq:NP_808908.1|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR012911(Protein serine/threonine phosphatase 2C, C-terminal)|interpro:IPR036457|interpro:IPR036580|mint:O75688|rcsb pdb:2P8E|reactome:R-HSA-1169408|ensembl:ENSG00000138032(gene)|ensembl:ENST00000282412(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0016020"(membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:cwwfGSSTv9pR/XNLa9UxQ/6hpD89606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P07900	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P68363	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P51957	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-8798332|ensembl:ENSP00000233027|uniprotkb:Q6P576|uniprotkb:A5YM70|uniprotkb:B7Z200|uniprotkb:B2R633	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:nek4_human(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:STK2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0097014"(ciliary plasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0030145"(manganese ion binding)|refseq:NP_001335342.1|refseq:NP_001180462.1|refseq:NP_003148.2	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P51957-2	uniprotkb:P62906	intact:EBI-20899477|ensembl:ENSP00000373227	intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722397|imex:IM-26491-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553	-	isoform-comment:No experimental confirmation available.	-	figure legend:st1 f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606	rigid:TkV+wwfdbmmozdv70zu+9aZFtpo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62258	uniprotkb:P51957-2	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	intact:EBI-20899477|ensembl:ENSP00000373227	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722568|imex:IM-26491-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:f5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rigid:g0FamWuPk4swMOawpTs5kNQZ4vo	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62258	uniprotkb:P51957-1	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	intact:EBI-20829359|ensembl:ENSP00000233027	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722568|imex:IM-26491-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	-	-	-	figure legend:f5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rigid:g0FamWuPk4swMOawpTs5kNQZ4vo	false	-	mutation disrupting interaction:35-36|flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12956	uniprotkb:P51957-2	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	intact:EBI-20899477|ensembl:ENSP00000373227	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722580|imex:IM-26491-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:f5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rigid:aIHUFXXe+YdslNYgf+b+FKZAvfM	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12956	uniprotkb:P51957-1	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	intact:EBI-20829359|ensembl:ENSP00000233027	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722580|imex:IM-26491-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	-	-	-	figure legend:f5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rigid:aIHUFXXe+YdslNYgf+b+FKZAvfM	false	-	mutation disrupting interaction:35-36|flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q07955	uniprotkb:P51957-2	intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962	intact:EBI-20899477|ensembl:ENSP00000373227	psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym)	psi-mi:p51957-2(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722592|imex:IM-26491-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A	intact:EBI-8798332(isoform-parent)|ensembl:ENSG00000114904(gene)|ensembl:ENST00000383721(transcript)|uniprotkb:P51957-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:f5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606	rogid:JllsdFWG8j/f/qGWGaKS/M2vADk9606	rigid:DLQaWa1xx2E7DSGQ8jPNmplsGQo	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q07955	uniprotkb:P51957-1	intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962	intact:EBI-20829359|ensembl:ENSP00000233027	psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym)	psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722592|imex:IM-26491-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent)	-	-	-	figure legend:f5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2018/07/23	2018/11/19	rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rigid:DLQaWa1xx2E7DSGQ8jPNmplsGQo	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12004	uniprotkb:P51957	intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458	intact:EBI-8798332|ensembl:ENSP00000233027|uniprotkb:Q6P576|uniprotkb:A5YM70|uniprotkb:B7Z200|uniprotkb:B2R633	psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:nek4_human(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:STK2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Basei et al. (2014)	imex:IM-26491|pubmed:25798074	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-20722611|imex:IM-26491-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N	ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0097014"(ciliary plasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0030145"(manganese ion binding)|refseq:NP_001335342.1|refseq:NP_001180462.1|refseq:NP_003148.2	go:"GO:0016605"(PML body)	-	-	comment:UV exposition-dependent|figure legend:f5b f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2018/07/23	2018/08/22	rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606	rogid:365hov+IcvvftTCyDltKgrlhdjM9606	rigid:871IGC4ps3iH3RBhmyvUTjHeyWc	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)