#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O08970 uniprotkb:P49452 intact:EBI-11795132|ensembl:ENSMUSP00000006123 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:tuft1_mouse(display_long)|uniprotkb:Tuft1(gene name)|psi-mi:Tuft1(display_short) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20738935|imex:IM-26823-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035786.1|ensembl:ENSMUSG00000005968(gene)|ensembl:ENSMUST00000006123(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR024846 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:umD2fg4uWQZyAWPmZr6ej7NAYRY10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:zQ5YLpbIpWErPydwK7uUiM7ZnYU false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BMP6 uniprotkb:P49452 intact:EBI-20739084|uniprotkb:O35371 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:gcp60_mouse(display_long)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym)|uniprotkb:Acbd3(gene name)|psi-mi:Acbd3(display_short)|uniprotkb:Gcp60(gene name synonym)|uniprotkb:Pap7(gene name synonym) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739120|imex:IM-26823-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-432722|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|refseq:NP_573488.2|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR035984|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR009038(GOLD)|interpro:IPR036598 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:VuUKgMaj73hD4hIf2lNHvHEFa3g10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:bkA6CeFBLi5HWN6lyjaI4vJaeLU false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8CHK4 uniprotkb:P49452 intact:EBI-1169948|uniprotkb:Q8CGZ3|uniprotkb:Q8CGZ4|uniprotkb:Q8VIH0|uniprotkb:A1L394|ensembl:ENSMUSP00000109271 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:kat5_mouse(display_long)|uniprotkb:Kat5(gene name)|psi-mi:Kat5(display_short)|uniprotkb:Htatip(gene name synonym)|uniprotkb:Tip60(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739126|imex:IM-26823-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186176.1|refseq:NP_001186177.1|refseq:NP_848752.1|ensembl:ENSMUST00000113641(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|ensembl:ENSMUSG00000024926(gene)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|mint:Q8CHK4|reactome:R-MMU-2559586|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693548|reactome:R-MMU-5693565|reactome:R-MMU-5693568|reactome:R-MMU-5693571|reactome:R-MMU-5693579|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-6804756|reactome:R-MMU-69473|reactome:R-MMU-9018519 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:HmCuP1tKkN1mA5x6VY8LlnwSfwY10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:VNyvvwUEx9FW44DLh3p3scsYKgs false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q60974 uniprotkb:P49452 intact:EBI-349004|uniprotkb:Q60812 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:ncor1_mouse(display_long)|uniprotkb:Ncor1(gene name)|psi-mi:Ncor1(display_short)|uniprotkb:Rxrip13(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein 13(gene name synonym) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739132|imex:IM-26823-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0002361"(CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021794"(thalamus development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051225"(spindle assembly)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:0046329"(negative regulation of JNK cascade)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|go:"GO:0046965"(retinoid X receptor binding)|reactome:R-MMU-383280|reactome:R-MMU-9029569|reactome:R-MMU-9623433|reactome:R-MMU-9707564|reactome:R-MMU-400206|mint:Q60974|dip:DIP-32548N ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:5IfmxD5K9s0dYCZ6AOMwaBDElFs10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:2974X5Ejwv0m7KQxaN+ejCBwG3A false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZQ12 uniprotkb:P49452 intact:EBI-20738977|ensembl:ENSMUSP00000105522|uniprotkb:A2ANB8|uniprotkb:Q6NXH6 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:ninl_mouse(display_long)|uniprotkb:Ninl(gene name)|psi-mi:Ninl(display_short)|uniprotkb:Kiaa0980(gene name synonym)|uniprotkb:Nlp(gene name synonym) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739138|imex:IM-26823-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000068115(gene)|ensembl:ENSMUST00000109896(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_997087.2 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:MblHu+lZetPkyA1aQBxfJ7OUPeA10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:GCfJjhpdpSeEzMWbheWhk3AbWZk false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14AW5 uniprotkb:P49452 intact:EBI-20739004|uniprotkb:Q8BS48|uniprotkb:Q9D5S9 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:nsun7_mouse(display_long)|uniprotkb:NOL1/NOP2/Sun domain family member 7(gene name synonym)|uniprotkb:Nsun7(gene name)|psi-mi:Nsun7(display_short) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739144|imex:IM-26823-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0032259"(methylation)|refseq:NP_001289762.1|refseq:NP_001289763.1|refseq:NP_081878.1|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR029063|interpro:IPR042620 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:iJR2zdSwCVj/wNlr/Xx0o8xWuzw10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:8wSZTaLKW/oxtm78SOpEpOk05/c false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BFX2 uniprotkb:P49452 intact:EBI-20738946|ensembl:ENSMUSP00000067049|ensembl:ENSMUSP00000156983 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:q8bfx2_mouse(display_long)|uniprotkb:Zfp438(gene name)|psi-mi:Zfp438(display_short) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739150|imex:IM-26823-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000050945(gene)|ensembl:ENSMUST00000063989(transcript)|ensembl:ENSMUST00000234241(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_848837.3|refseq:XP_006525968.1|refseq:XP_011245218.1 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:CbljVfLs1VFXtU8dX6MYywfp/vo10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:3Nz6tcTB/f+YSnQgPaCd7vuXMJI false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3V0M8 uniprotkb:P49452 intact:EBI-20738965 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:q3v0m8_mouse(display_long)|uniprotkb:BC051142(gene name)|psi-mi:BC051142(display_short)|uniprotkb:Tesb(gene name synonym)|uniprotkb:RP23-24A13.2-002(orf name) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739156|imex:IM-26823-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|refseq:XP_006524637.1|interpro:IPR038754 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:T5dwYoln/U9oz1Fzx3fEOrPeOEk10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:ujMKjXhAJYiFjeN+5lPQ0T0So58 false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5F2C3 uniprotkb:P49452 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739162|imex:IM-26823-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:BaO558zfFUKFJc3OuXluCHfkQfw false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80U72 uniprotkb:P49452 intact:EBI-1766028|uniprotkb:Q6P5H7|uniprotkb:Q7TPH8|uniprotkb:Q80VB1|uniprotkb:Q8CI48|uniprotkb:Q8VII1|uniprotkb:Q922S3|ensembl:ENSMUSP00000068056 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:scrib_mouse(display_long)|uniprotkb:Scrib(gene name)|psi-mi:Scrib(display_short)|uniprotkb:Kiaa0147(gene name synonym)|uniprotkb:Lap4(gene name synonym)|uniprotkb:Scrib1(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739168|imex:IM-26823-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_598850.1|refseq:XP_017171844.1|refseq:NP_001297471.1|refseq:NP_001297472.1|dip:DIP-40660N|ensembl:ENSMUSG00000022568(gene)|ensembl:ENSMUST00000063747(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008104"(protein localization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042060"(wound healing)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q80U72|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9696264|reactome:R-MMU-9696270 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:WF4b5QAjIGIgq6tnexNZtDhI7gk10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:i0sIMPUq6VWQKhQCT2Stt1w5cXg false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q60670 uniprotkb:P49452 intact:EBI-20739038|ensembl:ENSMUSP00000024839|uniprotkb:Q3UR46 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:sik1_mouse(display_long)|uniprotkb:HRT-20(gene name synonym)|uniprotkb:Myocardial SNF1-like kinase(gene name synonym)|uniprotkb:Salt-inducible kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNF1-like kinase 1(gene name synonym)|uniprotkb:Sik1(gene name)|psi-mi:Sik1(display_short)|uniprotkb:Msk(gene name synonym)|uniprotkb:Sik(gene name synonym)|uniprotkb:Snf1lk(gene name synonym) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739174|imex:IM-26823-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010830"(regulation of myotube differentiation)|go:"GO:0010868"(negative regulation of triglyceride biosynthetic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043276"(anoikis)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048511"(rhythmic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017090(Serine/threonine-protein kinase, SNF1-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034672|ensembl:ENSMUSG00000024042(gene)|ensembl:ENSMUST00000024839(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_034961.2 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:lZXyF/tuTwoU6evZCgoU6OUwNDM10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:tOwRBBwVGXL/50ZxvitIXWTcciU false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9D5A0 uniprotkb:P49452 intact:EBI-20739022|ensembl:ENSMUSP00000058522|uniprotkb:Q9D5X8 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:spesp_mouse(display_long)|uniprotkb:Spesp1(gene name)|psi-mi:Spesp1(display_short) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739180|imex:IM-26823-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000046846(gene)|ensembl:ENSMUST00000056949(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0007340"(acrosome reaction)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0009566"(fertilization)|go:"GO:0035036"(sperm-egg recognition)|interpro:IPR026743|refseq:NP_079997.1 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:1I8/CirGq5i2t9vEbuH2wCTlRks10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:dBvCxrfBj0H95JfpkY4IhL41hWI false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VCZ3 uniprotkb:P49452 intact:EBI-2366286|ensembl:ENSMUSP00000097701|ensembl:ENSMUSP00000156168 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:thap7_mouse(display_long)|uniprotkb:Thap7(gene name)|psi-mi:Thap7(display_short) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739186|imex:IM-26823-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081185.1|refseq:XP_006522574.1|ensembl:ENSMUSG00000022760(gene)|ensembl:ENSMUST00000100125(transcript)|ensembl:ENSMUST00000231548(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0106153"(phosphorylated histone binding)|go:"GO:0140296"(general transcription initiation factor binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026519 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:kmhoZr6XbQ1rbtg5ezGn/nH6WMM10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:7xc/VLDeeJPFIO1UJHb+CXGqFIk false - binding-associated region:692-906 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9QZL9 uniprotkb:Q5F2C3 intact:EBI-20739234|ensembl:ENSMUSP00000033057|uniprotkb:Q9EQT4|uniprotkb:Q9ERW0|uniprotkb:Q9ERW1 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:dkkl1_mouse(display_long)|uniprotkb:Protein soggy-1(gene name synonym)|uniprotkb:Dkkl1(gene name)|psi-mi:Dkkl1(display_short)|uniprotkb:Sgy1(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739318|imex:IM-26823-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030792(gene)|ensembl:ENSMUST00000033057(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005615"(extracellular space)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0039706"(co-receptor binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000225"(negative regulation of testosterone biosynthetic process)|interpro:IPR039863|refseq:NP_056604.2 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:y4uD2U6kF6c6LukkvGlxKw2VLo410090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:Pdh8GRR/0pmMrbgbzsbL7xz4YG8 false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6K1E7 uniprotkb:Q5F2C3 intact:EBI-3890502|uniprotkb:B9WZ58|uniprotkb:Q8C5T9|ensembl:ENSMUSP00000051800 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:ggnb1_mouse(display_long)|uniprotkb:Ggnbp1(gene name)|psi-mi:Ggnbp1(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739338|imex:IM-26823-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081820.2|ensembl:ENSMUSG00000048731(gene)|ensembl:ENSMUST00000053683(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|interpro:IPR026670|interpro:IPR028135 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:rvBBsQ2nMB3Z5bFAe9J0SViK1C410090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:k1M7XFgIGd5uy9F16I+nkVbLlI0 false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5F2C3 uniprotkb:Q8CHK4 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-1169948|uniprotkb:Q8CGZ3|uniprotkb:Q8CGZ4|uniprotkb:Q8VIH0|uniprotkb:A1L394|ensembl:ENSMUSP00000109271 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:kat5_mouse(display_long)|uniprotkb:Kat5(gene name)|psi-mi:Kat5(display_short)|uniprotkb:Htatip(gene name synonym)|uniprotkb:Tip60(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739344|imex:IM-26823-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_001186176.1|refseq:NP_001186177.1|refseq:NP_848752.1|ensembl:ENSMUST00000113641(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|ensembl:ENSMUSG00000024926(gene)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|mint:Q8CHK4|reactome:R-MMU-2559586|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693548|reactome:R-MMU-5693565|reactome:R-MMU-5693568|reactome:R-MMU-5693571|reactome:R-MMU-5693579|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-6804756|reactome:R-MMU-69473|reactome:R-MMU-9018519 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:HmCuP1tKkN1mA5x6VY8LlnwSfwY10090 rigid:ligiY2S2KNTRC1JEC64RzxWJlA4 false binding-associated region:272-434 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UL01 uniprotkb:Q5F2C3 intact:EBI-20739260|ensembl:ENSMUSP00000051408 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:morn2_mouse(display_long)|uniprotkb:MORN motif protein in testis(gene name synonym)|uniprotkb:Morn2(gene name)|psi-mi:Morn2(display_short)|uniprotkb:Mopt(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739350|imex:IM-26823-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045257(gene)|ensembl:ENSMUST00000061703(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|interpro:IPR003409(MORN motif)|refseq:NP_919245.1|refseq:XP_006524520.1|refseq:XP_011244809.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:MI09b8KjNN3HedwkVPUeUROFtis10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:0SA4PFSIddo+uruJDamN+6BiGk4 false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07832 uniprotkb:Q5F2C3 intact:EBI-2552999|ensembl:ENSMUSP00000033154 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:plk1_mouse(display_long)|uniprotkb:Plk(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:Plk1(gene name)|psi-mi:Plk1(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739356|imex:IM-26823-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030867(gene)|ensembl:ENSMUST00000033154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|interpro:IPR033702|interpro:IPR036947|rcsb pdb:5DMS|rcsb pdb:5DMV|rcsb pdb:5DNJ|rcsb pdb:5X3S|reactome:R-MMU-141444|reactome:R-MMU-156711|reactome:R-MMU-162658|reactome:R-MMU-174178|reactome:R-MMU-176412|reactome:R-MMU-176417|reactome:R-MMU-2299718|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2980767|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-68881|reactome:R-MMU-68884|reactome:R-MMU-69273|reactome:R-MMU-8852276|reactome:R-MMU-8854518|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|go:"GO:0000070"(mitotic sister chromatid segregation)|reactome:R-MMU-9648025|refseq:NP_035251.3|dip:DIP-56722N ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:YqF9DFVZSOmxF6QvN/X+kabo0lQ10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:cBIODWkk12Rgh1CO7i+m6iKOmmc false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5FWB9 uniprotkb:Q5F2C3 intact:EBI-20739252 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:q5fwb9_mouse(display_long)|uniprotkb:Selenov(gene name)|psi-mi:Selenov(display_short)|uniprotkb:BC089491(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739362|imex:IM-26823-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0010269"(response to selenium ion)|refseq:NP_778198.2|interpro:IPR011893(SelT/selW/selH selenoprotein)|interpro:IPR036249 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:59YMXsfrXIhpHpj2RQ4xAB0EN9Q10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:Ci9j2t1kPDZVGityZcXv4zgKmM8 false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9CQD0 uniprotkb:Q5F2C3 intact:EBI-20739212|ensembl:ENSMUSP00000041794|ensembl:ENSMUSP00000112791 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:q9cqd0_mouse(display_long)|uniprotkb:Rpl39l(gene name)|psi-mi:Rpl39l(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739368|imex:IM-26823-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039209(gene)|ensembl:ENSMUST00000044103(transcript)|ensembl:ENSMUST00000121292(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_080870.1|refseq:XP_006522569.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:V8xlQ+1WkeBH+B+06GRCaoTZCqE10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:cD62tIIfObdcrl/2V73x/OhTmMU false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CG49 uniprotkb:Q5F2C3 intact:EBI-6907378|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62991|uniprotkb:Q29120|ensembl:ENSMUSP00000019649|uniprotkb:Q9ET23|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:ubb_mouse(display_long)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739374|imex:IM-26823-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000019505(gene)|ensembl:ENSMUST00000019649(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060612"(adipose tissue development)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG49|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1253288|reactome:R-MMU-1295596|reactome:R-MMU-1358803|reactome:R-MMU-168638|reactome:R-MMU-174048|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-179409|reactome:R-MMU-182971|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-201681|reactome:R-MMU-202424|reactome:R-MMU-205043|reactome:R-MMU-209543|reactome:R-MMU-209560|reactome:R-MMU-2122948|reactome:R-MMU-2173788|reactome:R-MMU-2173791|reactome:R-MMU-2173795|reactome:R-MMU-2173796|reactome:R-MMU-2467813|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2565942|reactome:R-MMU-2672351|reactome:R-MMU-2871837|reactome:R-MMU-3134975|reactome:R-MMU-349425|reactome:R-MMU-3769402|reactome:R-MMU-382556|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-4641263|reactome:R-MMU-532668|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5675221|reactome:R-MMU-5675482|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-5685942|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689877|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-69017|reactome:R-MMU-69231|reactome:R-MMU-69481|reactome:R-MMU-69541|reactome:R-MMU-5689901|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-5693565|reactome:R-MMU-8849469|reactome:R-MMU-8852276|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696397|reactome:R-MMU-8854050|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8863795|reactome:R-MMU-8866652|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-8866654|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6783310|reactome:R-MMU-6804756|reactome:R-MMU-8939902|reactome:R-MMU-6804757|reactome:R-MMU-6804760|reactome:R-MMU-8941858|reactome:R-MMU-8948747|reactome:R-MMU-6807004|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-901032|reactome:R-MMU-9010553|reactome:R-MMU-9013507|reactome:R-MMU-9020702|reactome:R-MMU-9033241|reactome:R-MMU-912631|reactome:R-MMU-917729|reactome:R-MMU-917937|reactome:R-MMU-936440|reactome:R-MMU-936964|reactome:R-MMU-937039|reactome:R-MMU-937041|reactome:R-MMU-937042|reactome:R-MMU-937072|reactome:R-MMU-9645460|reactome:R-MMU-9646399|reactome:R-MMU-9648002|reactome:R-MMU-9664873|reactome:R-MMU-9705462|reactome:R-MMU-9706369|reactome:R-MMU-9708530|reactome:R-MMU-975144|reactome:R-MMU-975163|reactome:R-MMU-983168|refseq:NP_001300913.1|refseq:NP_035794.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:Rx+/zmzxbnmSyVdMSIgp6JvjLzs10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:I8MRViaYkPCWhtGIKTIjM6SAK+E false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9CQ84 uniprotkb:Q5F2C3 intact:EBI-20739276|ensembl:ENSMUSP00000100577|uniprotkb:Q5RL34 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:ubl4b_mouse(display_long)|uniprotkb:Ubl4b(gene name)|psi-mi:Ubl4b(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739380|imex:IM-26823-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000055891(gene)|ensembl:ENSMUST00000052853(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR000626(Ubiquitin)|interpro:IPR019956|interpro:IPR029071|interpro:IPR041421|interpro:IPR043317|refseq:NP_080537.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:zSDI+z780spxEHu4wAIrW/12an010090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:CkiKx17UUbN67kmfwMOnaiGEWk0 false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9D5I4 uniprotkb:Q5F2C3 intact:EBI-20739766|ensembl:ENSMUSP00000030248|ensembl:ENSMUSP00000112019|ensembl:ENSMUSP00000128228|uniprotkb:Q80ZP4|uniprotkb:Q9CVR8 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:dylt5_mouse(display_long)|uniprotkb:Dynlt5(gene name)|psi-mi:Dynlt5(display_short)|uniprotkb:Tctex1 domain-containing protein 1(gene name synonym)|uniprotkb:Tctex1d1(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739386|imex:IM-26823-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028523(gene)|ensembl:ENSMUST00000030248(transcript)|ensembl:ENSMUST00000116317(transcript)|ensembl:ENSMUST00000169211(transcript)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|reactome:R-MMU-5620924|refseq:NP_001157239.1|refseq:NP_080376.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:si7tqv+Pxc3AI31lH4JxlyZVoZc10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:b7jotOwlOKxlaT9NBz2v+qIjiGs false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49452 uniprotkb:Q5F2C3 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739560|imex:IM-26823-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:BaO558zfFUKFJc3OuXluCHfkQfw false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9QYI7 uniprotkb:Q5F2C3 intact:EBI-20739481|ensembl:ENSMUSP00000056592 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:dnjb8_mouse(display_long)|uniprotkb:mDj6(gene name synonym)|uniprotkb:Dnajb8(gene name)|psi-mi:Dnajb8(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739566|imex:IM-26823-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048206(gene)|ensembl:ENSMUST00000061866(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0090084"(negative regulation of inclusion body assembly)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|refseq:NP_064348.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:wqXSoGKzAI85FrGPFIWtAf6lUSM10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:MpQxxvrCfcD0Ehn+94E+nkk3CLo false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48024 uniprotkb:Q5F2C3 intact:EBI-8373107|uniprotkb:Q9WUD5|intact:MINT-4136107|ensembl:ENSMUSP00000041538 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:eif1_mouse(display_long)|uniprotkb:Eif1(gene name)|psi-mi:Eif1(display_short)|uniprotkb:Sui1(gene name synonym)|uniprotkb:Sui1-rs1(gene name synonym)|uniprotkb:Protein translation factor SUI1 homolog(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739572|imex:IM-26823-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035638.1|ensembl:ENSMUSG00000035530(gene)|ensembl:ENSMUST00000049385(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005874(Eukaryotic translation initiation factor SUI1)|interpro:IPR036877|mint:P48024 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - comment:mint|function:Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:nEEUMdnq/ms+jbMU74R7f+sF+LY10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:OEzf1CDelHHVcgPsYPzy9V8Okw8 false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DAN6 uniprotkb:Q5F2C3 intact:EBI-20739519|ensembl:ENSMUSP00000023129|ensembl:ENSMUSP00000114244|ensembl:ENSMUSP00000116366|ensembl:ENSMUSP00000119234|ensembl:ENSMUSP00000122193 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:gtsf1_mouse(display_long)|uniprotkb:Protein FAM112B(gene name synonym)|uniprotkb:Gtsf1(gene name)|psi-mi:Gtsf1(display_short)|uniprotkb:Cue110(gene name synonym)|uniprotkb:Fam112b(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739578|imex:IM-26823-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022487(gene)|ensembl:ENSMUST00000023129(transcript)|ensembl:ENSMUST00000136480(transcript)|ensembl:ENSMUST00000141364(transcript)|ensembl:ENSMUST00000146675(transcript)|ensembl:ENSMUST00000153930(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR007917(Protein of unknown function UPF0224)|interpro:IPR022776|interpro:IPR036236|rcsb pdb:6X46|refseq:NP_083073.1|refseq:XP_006521554.1|refseq:XP_011244051.1|refseq:XP_011244052.1|refseq:XP_011244053.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:1GcQwXhcM9q5M9aIdHfcXNRU+yE10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:aAaZRiHNpy1lODvWR3Cc+R8Z+jY false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9QY80 uniprotkb:Q5F2C3 intact:EBI-20739418|uniprotkb:Q9D6P7 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:hacd1_mouse(display_long)|uniprotkb:3-hydroxyacyl-CoA dehydratase 1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like member A(gene name synonym)|uniprotkb:Hacd1(gene name)|psi-mi:Hacd1(display_short)|uniprotkb:Ptpla(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739584|imex:IM-26823-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-75876|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014902"(myotube differentiation)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0034622"|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0046848"(hydroxyapatite binding)|go:"GO:0071529"(cementum mineralization)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|refseq:NP_038963.3|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:k/zHH9JUW96W4NSmCGU0i0YQ2Y010090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:onVWSSEiDwTAe7EGQp9NayKYJUk false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7TQE6 uniprotkb:Q5F2C3 intact:EBI-20739499|ensembl:ENSMUSP00000030628 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:macoi_mouse(display_long)|uniprotkb:Brain-specific adapter protein C61(gene name synonym)|uniprotkb:Macoilin-1(gene name synonym)|uniprotkb:Transmembrane protein 57(gene name synonym)|uniprotkb:Maco1(gene name)|psi-mi:Maco1(display_short)|uniprotkb:Tmem57(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739590|imex:IM-26823-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028826(gene)|ensembl:ENSMUST00000030628(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030424"(axon)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|interpro:IPR019130|reactome:R-MMU-8980692|reactome:R-MMU-9013106|refseq:NP_079658.2 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:0Ht76oGZsn36QRPu36qGFCMuAWY10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:eVhIm5L+d1DdlijwZG+iDd5DsCc false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9D3X9 uniprotkb:Q5F2C3 intact:EBI-20739388|ensembl:ENSMUSP00000034066|ensembl:ENSMUSP00000124330|ensembl:ENSMUSP00000125139|uniprotkb:Q80TV6|uniprotkb:Q8BJA9 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:mfa3l_mouse(display_long)|uniprotkb:Mfap3l(gene name)|psi-mi:Mfap3l(display_short)|uniprotkb:Kiaa0626(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739596|imex:IM-26823-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031647(gene)|ensembl:ENSMUST00000034066(transcript)|ensembl:ENSMUST00000160719(transcript)|ensembl:ENSMUST00000161702(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR039696|refseq:NP_001171352.1|refseq:NP_001171353.1|refseq:NP_001280698.1|refseq:NP_082032.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:zCsZ7AFYFDQwPwPfmoI67Iqu8iA10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:x047tXMuCPmh5lU7GHcgb67qV3Y false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P97393 uniprotkb:Q5F2C3 intact:EBI-645877|uniprotkb:E9Q0L8 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:rhg05_mouse(display_long)|uniprotkb:Rho-type GTPase-activating protein 5(gene name synonym)|uniprotkb:p190-B(gene name synonym)|uniprotkb:Arhgap5(gene name)|psi-mi:Arhgap5(display_short)|uniprotkb:Rhogap5(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739602|imex:IM-26823-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR032835|interpro:IPR027417|interpro:IPR039006|interpro:IPR039007|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030879"(mammary gland development)|go:"GO:0042169"(SH2 domain binding)|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273|interpro:IPR036517|mint:P97393 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:UZnXFwmIleOpeOC7GjMIOXOz2yg10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:XfMDjUdmRQbAXhTio7/ivMUyntg false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O88983 uniprotkb:Q5F2C3 intact:EBI-20739445|ensembl:ENSMUSP00000021285 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:stx8_mouse(display_long)|uniprotkb:Syntaxin-like protein 3I35(gene name synonym)|uniprotkb:Stx8(gene name)|psi-mi:Stx8(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739608|imex:IM-26823-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020903(gene)|ensembl:ENSMUST00000021285(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|refseq:NP_061238.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:Wq9sFb34i41bq6wQQLAzyY7iQjM10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:AEpbamkfc61uEwsBAuXgNW3n3rE false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P56818 uniprotkb:Q5F2C3 intact:EBI-11176383|uniprotkb:Q544D0|ensembl:ENSMUSP00000034591 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:bace1_mouse(display_long)|uniprotkb:Bace1(gene name)|psi-mi:Bace1(display_short)|uniprotkb:Bace(gene name synonym)|uniprotkb:Aspartyl protease 2(gene name synonym)|uniprotkb:Beta-site amyloid precursor protein cleaving enzyme 1(gene name synonym)|uniprotkb:Memapsin-2(gene name synonym)|uniprotkb:Membrane-associated aspartic protease 2(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739814|imex:IM-26823-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001139419.1|refseq:NP_035922.4|interpro:IPR033121|interpro:IPR033874|ensembl:ENSMUSG00000032086(gene)|ensembl:ENSMUST00000034591(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008233"(peptidase activity)|go:"GO:0009314"(response to radiation)|go:"GO:0009986"(cell surface)|go:"GO:0010288"(response to lead ion)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0055037"(recycling endosome)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR009119(Peptidase A1, beta-site APP cleaving enzyme, BACE)|interpro:IPR009120(Peptidase A1, beta-site APP cleaving enzyme 1, BACE 1)|interpro:IPR021109 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:QO/EXL+6QmtewuGnGQPrdHwGoyE10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:Sad6yrxu688SHMckG/0BI/QH5DE false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z2H5 uniprotkb:Q5F2C3 intact:EBI-774482|uniprotkb:Q3U3L1|uniprotkb:Q3UHP7|uniprotkb:Q80U34|uniprotkb:Q8K204 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:e41l1_mouse(display_long)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Epb41l1(gene name)|psi-mi:Epb41l1(display_short)|uniprotkb:Epb4(gene name synonym)|uniprotkb:Epb4.1l1(gene name synonym)|uniprotkb:Kiaa0338(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739820|imex:IM-26823-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278049.1|refseq:NP_001278051.1|refseq:NP_001278052.1|refseq:NP_001006665.1|refseq:NP_038538.1|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR019749|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR007477(SAB)|interpro:IPR029071|interpro:IPR035963|mint:Q9Z2H5|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0097060"(synaptic membrane)|reactome:R-MMU-399719|reactome:R-MMU-6794361 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:Lu31NnWhI356njHUtKbBlaO6nWE10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:nZiejFROGJmLWIksujh2Wt1o1kg false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WV92 uniprotkb:Q5F2C3 intact:EBI-911885|uniprotkb:Q69ZT8|ensembl:ENSMUSP00000079098|uniprotkb:Q9R102 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:e41l3_mouse(display_long)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Epb41l3(gene name)|psi-mi:Epb41l3(display_short)|uniprotkb:Dal1(gene name synonym)|uniprotkb:Epb4.1l3(gene name synonym)|uniprotkb:Kiaa0987(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739826|imex:IM-26823-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024044(gene)|ensembl:ENSMUST00000080208(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9WV92|reactome:R-MMU-6794361|refseq:NP_038841.1|refseq:XP_011244586.1|refseq:XP_011244591.1|refseq:XP_017172724.1|refseq:XP_017172725.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:51gkxiswTUqQbAUqjGoPthWD7jM10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:FseWkQaAL72PkWv8b+v35+AwK4M false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DCD6 uniprotkb:Q5F2C3 intact:EBI-10107623|uniprotkb:B1AR49|uniprotkb:Q9QUI7|ensembl:ENSMUSP00000018711 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:gbrap_mouse(display_long)|uniprotkb:Gabarap(gene name)|psi-mi:Gabarap(display_short)|uniprotkb:"GABA(A) receptor-associated protein"(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739832|imex:IM-26823-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062723.1|ensembl:ENSMUSG00000018567(gene)|ensembl:ENSMUST00000018711(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:5YIR|rcsb pdb:6A9X|reactome:R-MMU-1632852|reactome:R-MMU-8854214 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:PRC57VUrKgXozj1jnvgz7MQERK010090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:i+VbkwjuPDk0puDkTYPxHWjMLpw false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80XI3 uniprotkb:Q5F2C3 intact:EBI-11664146|uniprotkb:Q6GQV5|uniprotkb:Q80Y69|uniprotkb:Q8BJ68|uniprotkb:Q8BQF3|uniprotkb:Q8C6Q3|uniprotkb:Q8CIH0 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:if4g3_mouse(display_long)|uniprotkb:Eif4g3(gene name)|psi-mi:Eif4g3(display_short)|uniprotkb:eIF-4-gamma II(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739838|imex:IM-26823-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR037585|refseq:NP_766291.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|reactome:R-MMU-1169408|go:"GO:0000339"(RNA cap binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060903"(positive regulation of meiosis I) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:rZHNyp9tf03rooxy3bm2VgmUpBI10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:CGCYgRTskghGJ7Zba+Vz5j5pPxI false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80V86 uniprotkb:Q5F2C3 intact:EBI-20739743|ensembl:ENSMUSP00000038418|ensembl:ENSMUSP00000103955|uniprotkb:A2API4|uniprotkb:Q3TEM3|uniprotkb:Q3TNW0|uniprotkb:Q6PFD3|uniprotkb:Q810I3|uniprotkb:Q8BQJ8|uniprotkb:Q8BT91 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:int8_mouse(display_long)|uniprotkb:Ints8(gene name)|psi-mi:Ints8(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739844|imex:IM-26823-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040738(gene)|ensembl:ENSMUST00000044616(transcript)|ensembl:ENSMUST00000108319(transcript)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR038751|reactome:R-MMU-6807505|refseq:NP_001153067.1|refseq:NP_835213.3 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:8OWPjffm2AnqGsRdLq/myVQo2pE10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:t5Eharo7J9ori+L63mBaykHdXzA false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5F2C3 uniprotkb:Q14AW5 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-20739004|uniprotkb:Q8BS48|uniprotkb:Q9D5S9 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:nsun7_mouse(display_long)|uniprotkb:NOL1/NOP2/Sun domain family member 7(gene name synonym)|uniprotkb:Nsun7(gene name)|psi-mi:Nsun7(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739850|imex:IM-26823-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 go:"GO:0003723"(RNA binding)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0032259"(methylation)|refseq:NP_001289762.1|refseq:NP_001289763.1|refseq:NP_081878.1|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR029063|interpro:IPR042620 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:iJR2zdSwCVj/wNlr/Xx0o8xWuzw10090 rigid:RGaG+gK/QkgiUFfBZJ6qlQDLTB4 false binding-associated region:272-434 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DAG9 uniprotkb:Q5F2C3 intact:EBI-20739720|ensembl:ENSMUSP00000022459|uniprotkb:Q6PG81 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:phf7_mouse(display_long)|uniprotkb:Testis development protein NYD-SP6(gene name synonym)|uniprotkb:Phf7(gene name)|psi-mi:Phf7(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739856|imex:IM-26823-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021902(gene)|ensembl:ENSMUST00000022459(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR042012|interpro:IPR042013|rcsb pdb:1WEQ|refseq:NP_082225.1|refseq:XP_006519646.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:e9TYrCLJuORdc0GNgPiWH8LZLQY10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:N7KVXWmyGlFkjcHX3UJA6Zt+BcI false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8CF37 uniprotkb:Q5F2C3 intact:EBI-20739714 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:q8cf37_mouse(display_long)|uniprotkb:Smkr-ps(gene name)|psi-mi:Smkr-ps(display_short)|uniprotkb:1700023L04Rik(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739862|imex:IM-26823-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR037760 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:a0HtyUyXJkibvG7CKJHHw67WYrk10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:FeahPx6qeZQdbudALGqOG8mqYUc false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:D3YU81 uniprotkb:Q5F2C3 intact:EBI-20739784|ensembl:ENSMUSP00000121212 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:rfx8_mouse(display_long)|uniprotkb:Regulatory factor X 8(gene name synonym)|uniprotkb:Rfx8(gene name)|psi-mi:Rfx8(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739868|imex:IM-26823-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000057173(gene)|ensembl:ENSMUST00000151913(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|refseq:NP_001139132.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:HK9OmLrTjrETI9a+4EQt26r6j5M10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:mja1qLBUAnKBDCWCdwanvioiBSY false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ESG2 uniprotkb:Q5F2C3 intact:EBI-7153495|ensembl:ENSMUSP00000023530|uniprotkb:Q3TVG5|intact:MINT-112356 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:rop1_mouse(display_long)|uniprotkb:Ropn1(gene name)|psi-mi:Ropn1(display_short)|uniprotkb:Rhophilin-associated protein 1(gene name synonym)|uniprotkb:Rhophilin-associated 'oppo' protein(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739874|imex:IM-26823-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006522761.1|ensembl:ENSMUST00000023530(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0048240"(sperm capacitation)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097598"(sperm cytoplasmic droplet)|ensembl:ENSMUSG00000022832(gene)|refseq:NP_109669.1 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - comment:mint - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:a076CGb+HyS8tMFlJqshPvRBCe410090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:/0FKDVInVJhBGzByGtEC4z9Ftz4 false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9JJ80 uniprotkb:Q5F2C3 intact:EBI-8338126|uniprotkb:Q9CQ34|intact:MINT-4089446|uniprotkb:Q8R3K6|uniprotkb:Q9CSY9|uniprotkb:Q9CYR9|ensembl:ENSMUSP00000138581 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:rpf2_mouse(display_long)|uniprotkb:MNCb-4285(orf name)|uniprotkb:Rpf2(gene name)|psi-mi:Rpf2(display_short)|uniprotkb:Bxdc1(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF2 homolog(gene name synonym)|uniprotkb:Brix domain-containing protein 1(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739880|imex:IM-26823-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036021.1|refseq:NP_075812.3|ensembl:ENSMUSG00000038510(gene)|ensembl:ENSMUST00000183309(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007109(Brix)|interpro:IPR039770|mint:Q9JJ80 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - comment:mint - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:xZYCKNJa303YzXu/iMN/993ir6k10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:QY2iPp3FYnw1AkOkXfYIx9IgLhY false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P62309 uniprotkb:Q5F2C3 intact:EBI-8341016|uniprotkb:Q52KC7|uniprotkb:Q15357|intact:MINT-4133513|ensembl:ENSMUSP00000086987 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:ruxg_mouse(display_long)|uniprotkb:Snrpg(gene name)|psi-mi:Snrpg(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739886|imex:IM-26823-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080782.1|ensembl:ENSMUSG00000057278(gene)|ensembl:ENSMUST00000089558(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043186"(P granule)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|mint:P62309|reactome:R-MMU-111367|reactome:R-MMU-191859|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-73856|reactome:R-MMU-77588 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - function:Associated with snRNP U1, U2, U4/U6 and U5|comment:mint - figure legend:Extended Data Fig 7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/12 rogid:bwbnMaq7QstuUpgUyJtFqzF5J/I10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:PHrjDS5NmA4ctlJdjbI3cBPNX/E false - binding-associated region:272-434 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49452 uniprotkb:Q5F2C3 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739199|imex:IM-26823-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/12 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:BaO558zfFUKFJc3OuXluCHfkQfw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q07832 uniprotkb:Q5F2C3 intact:EBI-2552999|ensembl:ENSMUSP00000033154 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:plk1_mouse(display_long)|uniprotkb:Plk(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:Plk1(gene name)|psi-mi:Plk1(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739949|imex:IM-26823-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030867(gene)|ensembl:ENSMUST00000033154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|interpro:IPR033702|interpro:IPR036947|rcsb pdb:5DMS|rcsb pdb:5DMV|rcsb pdb:5DNJ|rcsb pdb:5X3S|reactome:R-MMU-141444|reactome:R-MMU-156711|reactome:R-MMU-162658|reactome:R-MMU-174178|reactome:R-MMU-176412|reactome:R-MMU-176417|reactome:R-MMU-2299718|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2980767|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-68881|reactome:R-MMU-68884|reactome:R-MMU-69273|reactome:R-MMU-8852276|reactome:R-MMU-8854518|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|go:"GO:0000070"(mitotic sister chromatid segregation)|reactome:R-MMU-9648025|refseq:NP_035251.3|dip:DIP-56722N ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Fig 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:YqF9DFVZSOmxF6QvN/X+kabo0lQ10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:cBIODWkk12Rgh1CO7i+m6iKOmmc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q07832 uniprotkb:Q5F2C3 intact:EBI-2552999|ensembl:ENSMUSP00000033154 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:plk1_mouse(display_long)|uniprotkb:Plk(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:Plk1(gene name)|psi-mi:Plk1(display_short) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739960|imex:IM-26823-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030867(gene)|ensembl:ENSMUST00000033154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|interpro:IPR033702|interpro:IPR036947|rcsb pdb:5DMS|rcsb pdb:5DMV|rcsb pdb:5DNJ|rcsb pdb:5X3S|reactome:R-MMU-141444|reactome:R-MMU-156711|reactome:R-MMU-162658|reactome:R-MMU-174178|reactome:R-MMU-176412|reactome:R-MMU-176417|reactome:R-MMU-2299718|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2980767|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-68881|reactome:R-MMU-68884|reactome:R-MMU-69273|reactome:R-MMU-8852276|reactome:R-MMU-8854518|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|go:"GO:0000070"(mitotic sister chromatid segregation)|reactome:R-MMU-9648025|refseq:NP_035251.3|dip:DIP-56722N ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/11/08 rogid:YqF9DFVZSOmxF6QvN/X+kabo0lQ10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:cBIODWkk12Rgh1CO7i+m6iKOmmc false - necessary binding region:385-434 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49452 uniprotkb:Q5F2C3 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739968|imex:IM-26823-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 - - - figure legend:Extended Data Fig 1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/13 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rigid:BaO558zfFUKFJc3OuXluCHfkQfw false binding-associated region:692-906 sufficient binding region:385-434 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A0A087WXM9 uniprotkb:Q03188 intact:EBI-20740139|ensembl:ENSP00000488568|uniprotkb:A0A0A8IBZ9 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:meikn_human(display_long)|uniprotkb:MEIKIN(gene name)|psi-mi:MEIKIN(display_short) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20740137|imex:IM-26823-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000239642(gene)|ensembl:ENST00000442687(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_001290551.1 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Extended Data Fig 9b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/13 rogid:08XXYJbAP7EqlafZmjn7UAGQD9M9606 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:C80rEKZq0+fi2Inh1kqnTcwYNlw false binding-associated region:259-373 sufficient binding region:730-943 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53350 uniprotkb:A0A087WXM9 intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093 intact:EBI-20740139|ensembl:ENSP00000488568|uniprotkb:A0A0A8IBZ9 psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym) psi-mi:meikn_human(display_long)|uniprotkb:MEIKIN(gene name)|psi-mi:MEIKIN(display_short) psi-mi:"MI:0018"(two hybrid) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20740163|imex:IM-26823-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N ensembl:ENSG00000239642(gene)|ensembl:ENST00000442687(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_001290551.1 - - - figure legend:Extended Data Fig 9b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/09/12 2018/09/13 rogid:fBOK366hV6mDprx9IWhz43gPcJE9606 rogid:08XXYJbAP7EqlafZmjn7UAGQD9M9606 rigid:BAxzKCqhG9Ywa5RbFh3/XHKcU1U false - binding-associated region:259-373 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50528 uniprotkb:Q9UTI4 intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep" intact:EBI-1564258|ensemblfungi:"SPAC15E1.07c.1:pep" psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name) psi-mi:moa1_schpo(display_long)|uniprotkb:moa1(gene name)|psi-mi:moa1(display_short)|uniprotkb:mug159(gene name synonym)|uniprotkb:SPAC15E1.07c(orf name)|uniprotkb:Meiotically up-regulated gene 159 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-20739983|imex:IM-26823-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025 refseq:NP_594308.1|ensemblfungi:SPAC15E1.07c(gene)|ensemblfungi:SPAC15E1.07c.1(transcript)|go:"GO:0000939"(inner kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0034090"(maintenance of meiotic sister chromatid cohesion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:1990813"(meiotic centromeric cohesion protection) - crc64:F11CD0EF9B913917 - figure legend:Fig 3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2018/09/12 2018/09/13 rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812 rogid:FvI/R9krbz3gSd72l+p6auK3WmE284812 rigid:Y+wCTEwzR2/mnurLLsUhLKNz1a8 false ha tag:n-n green fluorescent protein tag:c-c|v5 tag:?-? - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5F2C3 uniprotkb:Q8CGP6 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-8573727|ensembl:ENSMUSP00000089336|intact:MINT-4606203 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:h2a1h_mouse(display_long)|uniprotkb:H2ac12(gene name)|psi-mi:H2ac12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:Hist1h2ah(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000069302(gene)|ensembl:ENSMUST00000091742(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:2F8N|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5689901|reactome:R-MMU-606279|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|refseq:NP_783590.1 - - function:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling|comment:mint figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:pmWHTfvVU6PVP8ZlETv+BnTpug810090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q8BTI8 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-8328602|uniprotkb:E9QNB0|uniprotkb:Q3TBY5|uniprotkb:Q569P9|uniprotkb:Q80U37|intact:MINT-4112373|uniprotkb:Q8K383|ensembl:ENSMUSP00000139842 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:srrm2_mouse(display_long)|uniprotkb:Srrm2(gene name)|psi-mi:Srrm2(display_short)|uniprotkb:Kiaa0324(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_780438.2|refseq:XP_006525139.1|refseq:XP_006525140.1|ensembl:ENSMUSG00000039218(gene)|ensembl:ENSMUST00000190686(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945|mint:Q8BTI8|reactome:R-MMU-72163 - - function:Part of pre- and post-splicing multiprotein mRNP complexes. May be involved in pre-mRNA processing events. Binds to RNA|comment:mint figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:PTLJsCjqGftaxq5deG19BhEASWo10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q99MV1 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-8573364|ensembl:ENSMUSP00000077785|ensembl:ENSMUSP00000107231|ensembl:ENSMUSP00000107233|ensembl:ENSMUSP00000112786|uniprotkb:Q6F3G0|intact:MINT-8174270|uniprotkb:Q8K1G3|uniprotkb:Q8CDN7|uniprotkb:A2VDG6 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:tdrd1_mouse(display_long)|uniprotkb:Tdrd1(gene name)|psi-mi:Tdrd1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000025081(gene)|ensembl:ENSMUST00000078723(transcript)|ensembl:ENSMUST00000111604(transcript)|ensembl:ENSMUST00000111606(transcript)|ensembl:ENSMUST00000121249(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071546"(pi-body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR002999(Tudor)|interpro:IPR035437|rcsb pdb:4B9W|rcsb pdb:4B9X|refseq:NP_001002240.1|refseq:NP_001002238.1|refseq:NP_001002241.1|refseq:NP_113564.2|dip:DIP-48523N - - comment:mint figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:1fDrrjwmVOLzQe7uBXI/z6Fl8/410090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q91W39 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-8329509|uniprotkb:A2A5L2|intact:MINT-4103204|ensembl:ENSMUSP00000046388 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:ncoa5_mouse(display_long)|uniprotkb:Ncoa5(gene name)|psi-mi:Ncoa5(display_short)|uniprotkb:Coactivator independent of AF-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_659141.1|ensembl:ENSMUSG00000039804(gene)|ensembl:ENSMUST00000040381(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q91W39 - - comment:mint|function:"Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC/c-myc in response to 17-beta-estradiol (E2)" figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:wPwJKZRExN0LsGR8FyKm74oUm2g10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q61584 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-8350418|uniprotkb:Q9WUA8|intact:MINT-257148|uniprotkb:Q9R1E3|uniprotkb:Q8VCU4|uniprotkb:Q9R1E4|uniprotkb:Q9R1E2|uniprotkb:Q9WUA9|uniprotkb:Q9R1E5|uniprotkb:Q9WUA7|ensembl:ENSMUSP00000001620 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:fxr1_mouse(display_long)|uniprotkb:Fxr1(gene name)|psi-mi:Fxr1(display_short)|uniprotkb:Fxr1h(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_032079.1|refseq:NP_001106659.1|refseq:NP_001106660.1|refseq:XP_006535463.1|refseq:XP_006535464.1|refseq:XP_006535465.1|ensembl:ENSMUSG00000027680(gene)|ensembl:ENSMUST00000001620(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0007517"(muscle organ development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:Q61584|go:"GO:0005829"(cytosol) - - comment:mint|function:RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:llAsLdKtqlUDX3mK8DOwdYvnfw810090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q9JJZ2 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-8319860|uniprotkb:Q9CV57|uniprotkb:D4P911|intact:MINT-4137042|ensembl:ENSMUSP00000032233 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:tba8_mouse(display_long)|uniprotkb:Tuba8(gene name)|psi-mi:Tuba8(display_short)|uniprotkb:Alpha-tubulin 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_059075.1|ensembl:ENSMUSG00000030137(gene)|ensembl:ENSMUST00000032233(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9JJZ2|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5617833|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 - - comment:mint|function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:kSKDdPgABEPswCY1QpWaiYQjtlw10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:P62996 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-8320461|uniprotkb:O15449|uniprotkb:Q64283|intact:MINT-4138402|uniprotkb:Q15815|ensembl:ENSMUSP00000124846 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:tra2b_mouse(display_long)|uniprotkb:Silg41(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym)|uniprotkb:Silica-induced gene 41 protein(gene name synonym)|uniprotkb:Tra2b(gene name)|psi-mi:Tra2b(display_short)|uniprotkb:Sfrs10(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_033212.1|refseq:NP_001317483.1|refseq:NP_001317484.1|ensembl:ENSMUSG00000022858(gene)|ensembl:ENSMUST00000161286(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P62996|reactome:R-MMU-72163|reactome:R-MMU-9013418|reactome:R-MMU-9013422 - - comment:mint|function:Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:P38647 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q9CXY6 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-2312782|uniprotkb:Q3U083|uniprotkb:Q5RKG0|uniprotkb:Q8CCY9|uniprotkb:Q99KS3|ensembl:ENSMUSP00000001042 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:ilf2_mouse(display_long)|uniprotkb:Ilf2(gene name)|psi-mi:Ilf2(display_short)|uniprotkb:Nf45(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_080650.1|ensembl:ENSMUSG00000001016(gene)|ensembl:ENSMUST00000001042(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q9CXY6|rcsb pdb:4AT7|rcsb pdb:4AT8|rcsb pdb:4AT9|rcsb pdb:4ATB|reactome:R-MMU-6798695 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:P00342 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-6272871|ensembl:ENSMUSP00000014545 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:ldhc_mouse(display_long)|uniprotkb:Ldhc(gene name)|psi-mi:Ldhc(display_short)|uniprotkb:Ldh-3(gene name synonym)|uniprotkb:Ldh3(gene name synonym)|uniprotkb:LDH testis subunit(gene name synonym)|uniprotkb:LDH-X(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000030851(gene)|ensembl:ENSMUST00000014545(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019516"(lactate oxidation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:2LDX|refseq:XP_006540742.1|refseq:XP_006540743.1|refseq:XP_006540744.1|refseq:NP_038608.1 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:HhzPEL2pg1Z7UOkVbImxuKcJNE410090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q99KP6 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-6260977|uniprotkb:Q4ADG5|ensembl:ENSMUSP00000025642|uniprotkb:Q8BKZ5|uniprotkb:Q3TP64|uniprotkb:Q8BVQ4 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:prp19_mouse(display_long)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Prp19(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:Snev(gene name synonym)|uniprotkb:Prpf19(gene name)|psi-mi:Prpf19(display_short)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000024735(gene)|ensembl:ENSMUST00000025642(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q99KP6|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-72163|interpro:IPR019775|refseq:NP_001240772.1|refseq:NP_001240773.1|refseq:NP_598890.1 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:y9TwQBT+caDGqphA61AR5ysoqRg10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q9R0I7 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-644694|uniprotkb:E9QKY3|uniprotkb:Q7TMM4|ensembl:ENSMUSP00000098763 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:ylpm1_mouse(display_long)|uniprotkb:Nuclear protein ZAP3(gene name synonym)|uniprotkb:Ylpm1(gene name)|psi-mi:Ylpm1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:Zap3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 go:"GO:0032204"(regulation of telomere maintenance)|interpro:IPR026314|ensembl:ENSMUSG00000021244(gene)|ensembl:ENSMUST00000101202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|interpro:IPR027417|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|mint:Q9R0I7|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck) - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:+1aQLNgVl385Mxmx32eA6x9ccDg10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q07832 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-2552999|ensembl:ENSMUSP00000033154 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:plk1_mouse(display_long)|uniprotkb:Plk(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:Plk1(gene name)|psi-mi:Plk1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000030867(gene)|ensembl:ENSMUST00000033154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|interpro:IPR033702|interpro:IPR036947|rcsb pdb:5DMS|rcsb pdb:5DMV|rcsb pdb:5DNJ|rcsb pdb:5X3S|reactome:R-MMU-141444|reactome:R-MMU-156711|reactome:R-MMU-162658|reactome:R-MMU-174178|reactome:R-MMU-176412|reactome:R-MMU-176417|reactome:R-MMU-2299718|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2980767|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-68881|reactome:R-MMU-68884|reactome:R-MMU-69273|reactome:R-MMU-8852276|reactome:R-MMU-8854518|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|go:"GO:0000070"(mitotic sister chromatid segregation)|reactome:R-MMU-9648025|refseq:NP_035251.3|dip:DIP-56722N - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:YqF9DFVZSOmxF6QvN/X+kabo0lQ10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q8C2Q3 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-5692318|uniprotkb:Q3TJB6|uniprotkb:Q91Z21|uniprotkb:Q9DBI6|ensembl:ENSMUSP00000006625 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:rbm14_mouse(display_long)|uniprotkb:Rbm14(gene name)|psi-mi:Rbm14(display_short)|uniprotkb:RNA-binding motif protein 14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_063922.2|dip:DIP-58946N|ensembl:ENSMUSG00000006456(gene)|ensembl:ENSMUST00000006625(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0098534"(centriole assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|interpro:IPR035979|mint:Q8C2Q3|reactome:R-MMU-8941326 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:0jBdPL/CBCwYLIf2A76qx0yJ9RY10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q99PV0 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-2551815|ensembl:ENSMUSP00000018449|ensembl:ENSMUSP00000099568|uniprotkb:A5D6Q4|uniprotkb:Q7TQK2|uniprotkb:Q8BRZ5|uniprotkb:Q8K001|uniprotkb:Q5ND30|uniprotkb:Q5ND31 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:prp8_mouse(display_long)|uniprotkb:Prp8(gene name synonym)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:Prpf8(gene name)|psi-mi:Prpf8(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000020850(gene)|ensembl:ENSMUST00000018449(transcript)|ensembl:ENSMUST00000102510(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q99PV0|reactome:R-MMU-72163|reactome:R-MMU-72165|interpro:IPR037518|refseq:NP_619600.2 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:vHccw48piO1PjsNcxDszzscPO8010090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:O35737 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-299747|ensembl:ENSMUSP00000070503|ensembl:ENSMUSP00000104770 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:hnrh1_mouse(display_long)|uniprotkb:Hnrnph1(gene name)|psi-mi:Hnrnph1(display_short)|uniprotkb:Hnrph(gene name synonym)|uniprotkb:Hnrph1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000007850(gene)|ensembl:ENSMUST00000069304(transcript)|ensembl:ENSMUST00000109142(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:O35737|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:NP_067485.1|refseq:XP_017170179.1|refseq:XP_017170180.1 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:nBSCiXDDfkwqslFAXPXlDzC+5e410090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:O70133 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-2657677|uniprotkb:O35931|uniprotkb:O54703|uniprotkb:Q5FWY1|uniprotkb:Q6R5F7|uniprotkb:Q9CSA2 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:dhx9_mouse(display_long)|uniprotkb:Dhx9(gene name)|psi-mi:Dhx9(display_short)|uniprotkb:Ddx9(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_031868.2|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005844"(polysome)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904973"(positive regulation of viral translation)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|rcsb pdb:1UIL|rcsb pdb:1WHQ|rcsb pdb:2RS6|rcsb pdb:2RS7|reactome:R-MMU-1810476|reactome:R-MMU-3134963|reactome:R-MMU-72163|interpro:IPR027417|mint:O70133|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:8NHxvbw0StglewhGm3e7Pi/8oOg10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q6P4T2 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-6878408|ensembl:ENSMUSP00000099509|uniprotkb:Q69ZZ3 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:u520_mouse(display_long)|uniprotkb:Snrnp200(gene name)|psi-mi:Snrnp200(display_short)|uniprotkb:Kiaa0788(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000003660(gene)|ensembl:ENSMUST00000103220(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:Q6P4T2|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_796188.2 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:P0APWhAjy05E6VYhOWEmHdw2QHw10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q9Z2X1 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-4283704|uniprotkb:Q5FWK2|uniprotkb:Q8BVU8|uniprotkb:Q8K2U9|uniprotkb:Q8R0E7|ensembl:ENSMUSP00000045048|ensembl:ENSMUSP00000126817|ensembl:ENSMUSP00000130023|ensembl:ENSMUSP00000136700|ensembl:ENSMUSP00000137632 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:hnrpf_mouse(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_001159899.1|refseq:NP_001159900.1|refseq:NP_001159901.1|refseq:NP_001159902.1|refseq:NP_001159903.1|refseq:NP_001159904.1|refseq:NP_598595.1|refseq:XP_006506892.1|ensembl:ENSMUSG00000042079(gene)|ensembl:ENSMUST00000035493(transcript)|ensembl:ENSMUST00000163168(transcript)|ensembl:ENSMUST00000167182(transcript)|ensembl:ENSMUST00000180020(transcript)|ensembl:ENSMUST00000180341(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|rcsb pdb:2DB1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|mint:Q9Z2X1 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q91VC3 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-2552399|ensembl:ENSMUSP00000026667|uniprotkb:Q3UD29|uniprotkb:Q3TEZ8|uniprotkb:B2RY38|uniprotkb:Q8BVY3 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:if4a3_mouse(display_long)|uniprotkb:Eif4a3(gene name)|psi-mi:Eif4a3(display_short)|uniprotkb:Ddx48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 reactome:R-MMU-975957|ensembl:ENSMUSG00000025580(gene)|ensembl:ENSMUST00000026667(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|refseq:NP_619610.1|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q91VC3|reactome:R-MMU-1169408|reactome:R-MMU-159236|reactome:R-MMU-429947|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:6jjMHbLWWbe2j3Qv+g8b/PbY7Ps10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q9CQL1 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-12514027|uniprotkb:Q78Y23 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:mgn2_mouse(display_long)|uniprotkb:Magohb(gene name)|psi-mi:Magohb(display_short)|uniprotkb:Magoh-rs1(gene name synonym)|uniprotkb:Magoh2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-975957|refseq:NP_079840.2|interpro:IPR004023(Mago nashi protein)|refseq:NP_001314789.1|interpro:IPR036605 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:jFLiWOV3BtMx29gvl2hWe3aZxpY10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:P49452 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-1186252|ensembl:ENSMUSP00000031170|uniprotkb:B9EK81 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:cenpc_mouse(display_long)|uniprotkb:Cenpc(gene name)|psi-mi:Cenpc(display_short)|uniprotkb:Cenpc1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000029253(gene)|ensembl:ENSMUST00000031170(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_031709.2|refseq:NP_001332831.1|refseq:NP_001332832.1|refseq:NP_001332833.1|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:P49452|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-606279|reactome:R-MMU-68877|reactome:R-MMU-9648025 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:SMUVTxffzXpm/8r8dS4FhFj7fBU10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q8K310 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-1216295|ensembl:ENSMUSP00000125761|ensembl:ENSMUSP00000158074|ensembl:ENSMUSP00000158537 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:matr3_mouse(display_long)|uniprotkb:Matr3(gene name)|psi-mi:Matr3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_034901.2|rcsb pdb:1X4F|rcsb pdb:1X4D|ensembl:ENSMUSG00000037236(gene)|ensembl:ENSMUST00000166793(transcript)|ensembl:ENSMUST00000235199(transcript)|ensembl:ENSMUST00000237744(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:Q8K310 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:AwtFbI+oRfha+mn/v3yzG6bNXYg10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:P99024 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q9D0E1 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-773789|uniprotkb:Q6P1B2|uniprotkb:Q99JQ0|ensembl:ENSMUSP00000120115 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:hnrpm_mouse(display_long)|uniprotkb:Hnrpm(gene name synonym)|uniprotkb:Hnrnpm(gene name)|psi-mi:Hnrnpm(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 refseq:NP_001103383.1|refseq:NP_084080.1|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904591"(positive regulation of protein import)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:Q9D0E1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000059208(gene)|ensembl:ENSMUST00000148178(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0048306"(calcium-dependent protein binding) - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:VpoWJwPx1uDzAsBxM3/TfiCMGok10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q5F2C3 uniprotkb:Q569Z6 intact:EBI-20739301|ensembl:ENSMUSP00000091745|uniprotkb:Q3KNB2 intact:EBI-2536252|ensembl:ENSMUSP00000079722 psi-mi:meikn_mouse(display_long)|uniprotkb:Meikin(gene name)|psi-mi:Meikin(display_short) psi-mi:tr150_mouse(display_long)|uniprotkb:Thrap3(gene name)|psi-mi:Thrap3(display_short)|uniprotkb:Trap150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:25533956|imex:IM-26823 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-20739920|imex:IM-26823-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020332(gene)|ensembl:ENSMUST00000094193(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0010789"(meiotic sister chromatid cohesion involved in meiosis I)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR034545|refseq:NP_083381.1 ensembl:ENSMUSG00000043962(gene)|ensembl:ENSMUST00000080919(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR026667|interpro:IPR029199|go:"GO:0008380"(RNA splicing)|refseq:XP_011238805.1|refseq:NP_666265.3|refseq:XP_006503104.1 - - - figure legend:Extended Data Fig 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2018/09/12 2018/09/13 rogid:Po9YjvU9RGbwpYxJyPaWqAgM++s10090 rogid:Cb0vHuEX3Ew27z2gvfC/36tdeYE10090 rigid:ug76aSrPK5Y0jsPaZHfr0EU+2LM false - - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology)