#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P53141	uniprotkb:Q12280	intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40	intact:EBI-35351|uniprotkb:D6W3C9|ensemblfungi:YPL242C	psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym)	psi-mi:iqg1_yeast(display_long)|uniprotkb:IQG1(gene name)|psi-mi:IQG1(display_short)|uniprotkb:CYK1(gene name synonym)|uniprotkb:IQGAP-related protein 1(gene name synonym)|uniprotkb:Cytokinesis protein 1(gene name synonym)|uniprotkb:YPL242C(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Tian et al. (2014)	imex:IM-26401|pubmed:24895401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20557474|imex:IM-26401-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N	refseq:NP_015082.1|sgd:S000006163|mint:Q12280|dip:DIP-1144N|ensemblfungi:YPL242C(gene)|ensemblfungi:YPL242C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007165"(signal transduction)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120155"(MIH complex)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903479"(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036872|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013406	-	crc64:D7508123C101E4A6	-	figure legend:Fig. 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/05/03	2018/05/03	rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292	rogid:Xe3LSR8m2pfYpup/TbfpM+UZjzI559292	rigid:1Ed0sBJ+vAmJ2Ty6KukvFVFzVZo	false	nub:?-?	sufficient binding region:657-743|cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05080	uniprotkb:Q12280	intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W	intact:EBI-35351|uniprotkb:D6W3C9|ensemblfungi:YPL242C	psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym)	psi-mi:iqg1_yeast(display_long)|uniprotkb:IQG1(gene name)|psi-mi:IQG1(display_short)|uniprotkb:CYK1(gene name synonym)|uniprotkb:IQGAP-related protein 1(gene name synonym)|uniprotkb:Cytokinesis protein 1(gene name synonym)|uniprotkb:YPL242C(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Tian et al. (2014)	imex:IM-26401|pubmed:24895401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20558049|imex:IM-26401-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828	refseq:NP_015082.1|sgd:S000006163|mint:Q12280|dip:DIP-1144N|ensemblfungi:YPL242C(gene)|ensemblfungi:YPL242C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007165"(signal transduction)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120155"(MIH complex)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903479"(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036872|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013406	-	crc64:AE4A76C2F4043021	-	figure legend:Fig. 1A, 1B, 3A, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/05/03	2018/05/04	rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292	rogid:Xe3LSR8m2pfYpup/TbfpM+UZjzI559292	rigid:WFmsOorDSTdKecJIokGaKgKaDW0	false	nub:?-?|sufficient binding region:283-592	mutation disrupting interaction strength:667-667|sufficient binding region:657-743|cub:?-?|mutation disrupting interaction strength:695-695|mutation disrupting interaction strength:667-667,695-695|mutation with no effect:725-725	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53141	uniprotkb:Q12280	intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40	intact:EBI-35351|uniprotkb:D6W3C9|ensemblfungi:YPL242C	psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym)	psi-mi:iqg1_yeast(display_long)|uniprotkb:IQG1(gene name)|psi-mi:IQG1(display_short)|uniprotkb:CYK1(gene name synonym)|uniprotkb:IQGAP-related protein 1(gene name synonym)|uniprotkb:Cytokinesis protein 1(gene name synonym)|uniprotkb:YPL242C(locus name)	psi-mi:"MI:0096"(pull down)	Tian et al. (2014)	imex:IM-26401|pubmed:24895401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20558098|imex:IM-26401-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N	refseq:NP_015082.1|sgd:S000006163|mint:Q12280|dip:DIP-1144N|ensemblfungi:YPL242C(gene)|ensemblfungi:YPL242C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007165"(signal transduction)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120155"(MIH complex)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903479"(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036872|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013406	-	crc64:D7508123C101E4A6	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/03	2018/05/04	rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292	rogid:Xe3LSR8m2pfYpup/TbfpM+UZjzI559292	rigid:1Ed0sBJ+vAmJ2Ty6KukvFVFzVZo	false	glutathione s tranferase tag:?-?	tag:n-n|his tag:n-n|sufficient binding region:657-743	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P53141	uniprotkb:Q05080	intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40	intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W	psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym)	psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tian et al. (2014)	imex:IM-26401|pubmed:24895401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20558196|imex:IM-26401-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N	refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828	-	crc64:D7508123C101E4A6	crc64:AE4A76C2F4043021	figure legend:Fig. 2B, 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/03	2018/05/14	rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292	rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292	rigid:b2YpsOB1NoPNkyqOZzoAyUgeAdw	false	glutathione s tranferase tag:?-?	myc tag:?-?|sufficient binding region:283-592	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P53141	uniprotkb:Q12280	intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40	intact:EBI-35351|uniprotkb:D6W3C9|ensemblfungi:YPL242C	psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym)	psi-mi:iqg1_yeast(display_long)|uniprotkb:IQG1(gene name)|psi-mi:IQG1(display_short)|uniprotkb:CYK1(gene name synonym)|uniprotkb:IQGAP-related protein 1(gene name synonym)|uniprotkb:Cytokinesis protein 1(gene name synonym)|uniprotkb:YPL242C(locus name)	psi-mi:"MI:0096"(pull down)	Tian et al. (2014)	imex:IM-26401|pubmed:24895401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20558196|imex:IM-26401-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N	refseq:NP_015082.1|sgd:S000006163|mint:Q12280|dip:DIP-1144N|ensemblfungi:YPL242C(gene)|ensemblfungi:YPL242C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007165"(signal transduction)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120155"(MIH complex)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903479"(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036872|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013406	-	crc64:D7508123C101E4A6	-	figure legend:Fig. 2B, 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/03	2018/05/14	rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292	rogid:Xe3LSR8m2pfYpup/TbfpM+UZjzI559292	rigid:b2YpsOB1NoPNkyqOZzoAyUgeAdw	false	glutathione s tranferase tag:?-?	mutation disrupting interaction strength:667-667,695-695|mutation decreasing interaction strength:667-667|mutation disrupting interaction strength:695-695|his tag:n-n|tag:?-?|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P53141	uniprotkb:Q05080	intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40	intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W	psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym)	psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tian et al. (2014)	imex:IM-26401|pubmed:24895401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20558213|imex:IM-26401-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N	refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828	-	crc64:D7508123C101E4A6	crc64:AE4A76C2F4043021	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/03	2018/05/14	rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292	rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292	rigid:b2YpsOB1NoPNkyqOZzoAyUgeAdw	false	glutathione s tranferase tag:?-?	maltose binding protein tag:?-?|sufficient binding region:283-592	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P53141	uniprotkb:Q12280	intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40	intact:EBI-35351|uniprotkb:D6W3C9|ensemblfungi:YPL242C	psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym)	psi-mi:iqg1_yeast(display_long)|uniprotkb:IQG1(gene name)|psi-mi:IQG1(display_short)|uniprotkb:CYK1(gene name synonym)|uniprotkb:IQGAP-related protein 1(gene name synonym)|uniprotkb:Cytokinesis protein 1(gene name synonym)|uniprotkb:YPL242C(locus name)	psi-mi:"MI:0096"(pull down)	Tian et al. (2014)	imex:IM-26401|pubmed:24895401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20558213|imex:IM-26401-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N	refseq:NP_015082.1|sgd:S000006163|mint:Q12280|dip:DIP-1144N|ensemblfungi:YPL242C(gene)|ensemblfungi:YPL242C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007165"(signal transduction)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120155"(MIH complex)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903479"(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036872|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013406	-	crc64:D7508123C101E4A6	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/03	2018/05/14	rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292	rogid:Xe3LSR8m2pfYpup/TbfpM+UZjzI559292	rigid:b2YpsOB1NoPNkyqOZzoAyUgeAdw	false	glutathione s tranferase tag:?-?	tag:n-n|sufficient binding region:657-743|his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q05080	uniprotkb:Q12280	intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W	intact:EBI-35351|uniprotkb:D6W3C9|ensemblfungi:YPL242C	psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym)	psi-mi:iqg1_yeast(display_long)|uniprotkb:IQG1(gene name)|psi-mi:IQG1(display_short)|uniprotkb:CYK1(gene name synonym)|uniprotkb:IQGAP-related protein 1(gene name synonym)|uniprotkb:Cytokinesis protein 1(gene name synonym)|uniprotkb:YPL242C(locus name)	psi-mi:"MI:0416"(fluorescence microscopy)	Tian et al. (2014)	imex:IM-26401|pubmed:24895401	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20558366|imex:IM-26401-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828	refseq:NP_015082.1|sgd:S000006163|mint:Q12280|dip:DIP-1144N|ensemblfungi:YPL242C(gene)|ensemblfungi:YPL242C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007165"(signal transduction)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120155"(MIH complex)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903479"(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036872|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013406	go:"GO:0005886"(plasma membrane)	crc64:AE4A76C2F4043021	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/05/03	2018/05/04	rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292	rogid:Xe3LSR8m2pfYpup/TbfpM+UZjzI559292	rigid:WFmsOorDSTdKecJIokGaKgKaDW0	false	green fluorescent protein tag:?-?	tag:?-?|sufficient binding region:657-743|mcherry fluorescent protein tag:?-?|mutation disrupting interaction strength:667-667,695-695	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)