#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P30419	uniprotkb:P42574	intact:EBI-5280164|uniprotkb:A8K7C1|uniprotkb:Q9UE09|ensembl:ENSP00000258960|ensembl:ENSP00000468424|ensembl:ENSP00000504192	intact:EBI-524064|ensembl:ENSP00000311032|ensembl:ENSP00000428929|uniprotkb:Q96AN1|uniprotkb:Q96KP2|uniprotkb:A8K5M2|uniprotkb:D3DP53	psi-mi:nmt1_human(display_long)|uniprotkb:NMT1(gene name)|psi-mi:NMT1(display_short)|uniprotkb:NMT(gene name synonym)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 1"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 1(gene name synonym)	psi-mi:casp3_human(display_long)|uniprotkb:Apopain(gene name synonym)|uniprotkb:Cysteine protease CPP32(gene name synonym)|uniprotkb:Protein Yama(gene name synonym)|uniprotkb:SREBP cleavage activity 1(gene name synonym)|uniprotkb:CASP3(gene name)|psi-mi:CASP3(display_short)|uniprotkb:CPP32(gene name synonym)	psi-mi:"MI:0990"(cleavage assay)	Perinpanayagam et al. (2013)	pubmed:23150525|imex:IM-27162	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21278779|imex:IM-27162-1	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066565.1|ensembl:ENSG00000136448(gene)|ensembl:ENST00000258960(transcript)|ensembl:ENST00000592782(transcript)|ensembl:ENST00000676828(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019107"(myristoyltransferase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0042180"(cellular ketone metabolic process)|go:"GO:1900740"(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:1RXT|rcsb pdb:3IU1|rcsb pdb:3IU2|rcsb pdb:3IWE|rcsb pdb:3JTK|rcsb pdb:4C2Y|rcsb pdb:4C2Z|rcsb pdb:5MU6|rcsb pdb:5NPQ|rcsb pdb:5O6H|rcsb pdb:5O6J|rcsb pdb:5O9S|rcsb pdb:5O9T|rcsb pdb:5O9U|rcsb pdb:5O9V|rcsb pdb:5UUT|rcsb pdb:6EHJ|rcsb pdb:6F56|rcsb pdb:6FZ2|rcsb pdb:6FZ3|rcsb pdb:6FZ5|rcsb pdb:6PAV|rcsb pdb:6QRM|rcsb pdb:6SJZ|rcsb pdb:6SK2|rcsb pdb:6SK3|rcsb pdb:6SK8|rcsb pdb:6SKJ|reactome:R-HSA-162599|reactome:R-HSA-2514859|reactome:R-HSA-75108|go:"GO:0005737"(cytoplasm)	go:"GO:0009749"(response to glucose)|go:"GO:0001554"(luteolysis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002020"(protease binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000164305(gene)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|ensembl:ENST00000308394(transcript)|ensembl:ENST00000523916(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0008233"(peptidase activity)|go:"GO:0008627"(intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0016005"(phospholipase A2 activator activity)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016485"(protein processing)|go:"GO:0021766"(hippocampus development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035094"(response to nicotine)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061713"(anterior neural tube closure)|go:"GO:0071887"(leukocyte apoptotic process)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|rcsb pdb:1GFW|rcsb pdb:1I3O|rcsb pdb:1NME|rcsb pdb:1NMQ|rcsb pdb:1NMS|interpro:IPR015471(Caspase-7)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|mint:P42574|interpro:IPR002398(Peptidase C14, caspase precursor p45)|rcsb pdb:1CP3|rcsb pdb:4QUH|rcsb pdb:4QUI|rcsb pdb:4QUD|rcsb pdb:4QUJ|rcsb pdb:4QUL|rcsb pdb:5I9B|rcsb pdb:5I9T|rcsb pdb:5IAB|rcsb pdb:5IAE|rcsb pdb:5IAG|rcsb pdb:4QUE|rcsb pdb:5IAJ|rcsb pdb:4QUG|rcsb pdb:5IAK|rcsb pdb:5IAN|rcsb pdb:5IAR|rcsb pdb:5IAS|rcsb pdb:5IBC|rcsb pdb:5IBP|rcsb pdb:5IBR|rcsb pdb:5IC4|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111465|reactome:R-HSA-111469|reactome:R-HSA-140342|reactome:R-HSA-1474228|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-211736|reactome:R-HSA-264870|reactome:R-HSA-351906|reactome:R-HSA-418889|reactome:R-HSA-449836|reactome:R-HSA-5620971|reactome:R-HSA-111464|rcsb pdb:1QX3|rcsb pdb:1RE1|rcsb pdb:1RHJ|rcsb pdb:1RHK|rcsb pdb:1RHM|rcsb pdb:1RHQ|rcsb pdb:1RHR|rcsb pdb:1RHU|rcsb pdb:2C1E|rcsb pdb:2C2K|rcsb pdb:2C2M|rcsb pdb:2C2O|rcsb pdb:2CDR|rcsb pdb:2CJX|rcsb pdb:2CJY|rcsb pdb:2CNK|rcsb pdb:2CNL|rcsb pdb:2CNN|rcsb pdb:2CNO|rcsb pdb:2DKO|rcsb pdb:2H5I|rcsb pdb:2H5J|rcsb pdb:2H65|rcsb pdb:2J30|rcsb pdb:2J31|rcsb pdb:2J32|rcsb pdb:2J33|rcsb pdb:2XYG|rcsb pdb:2XYH|rcsb pdb:2XYP|rcsb pdb:2XZD|rcsb pdb:2XZT|rcsb pdb:2Y0B|rcsb pdb:3DEH|rcsb pdb:1PAU|rcsb pdb:3DEI|rcsb pdb:3DEJ|rcsb pdb:3DEK|rcsb pdb:3EDQ|rcsb pdb:3GJQ|rcsb pdb:3GJS|rcsb pdb:3GJT|rcsb pdb:3H0E|rcsb pdb:3ITN|rcsb pdb:3KJF|rcsb pdb:3PCX|rcsb pdb:3PD0|rcsb pdb:3PD1|rcsb pdb:4DCJ|rcsb pdb:4DCO|rcsb pdb:4DCP|rcsb pdb:4EHA|rcsb pdb:4EHD|rcsb pdb:4EHF|rcsb pdb:4EHH|rcsb pdb:4EHK|rcsb pdb:4EHL|rcsb pdb:4EHN|rcsb pdb:4JJE|rcsb pdb:4JQY|rcsb pdb:4JQZ|rcsb pdb:4JR0|rcsb pdb:4PRY|rcsb pdb:4PS0|rcsb pdb:4QTX|rcsb pdb:3GJR|rcsb pdb:4QTY|rcsb pdb:4QU0|rcsb pdb:4QU5|rcsb pdb:4QU8|rcsb pdb:4QU9|rcsb pdb:4QUA|rcsb pdb:4QUB|refseq:XP_011530603.1|refseq:NP_004337.2|refseq:NP_116786.1|dip:DIP-268N	-	-	-	figure legend:Figure 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/03/20	rogid:eVkADRJp/cg4xIAw0ymeUZ+Vwyk9606	rogid:o7/WP52saFha1/FD2z1rIgVLDfI9606	rigid:yjViwnYsQ/TJTRkCCgtyaQ6OmmQ	false	his tag:n-n|biological feature:72-73	his tag:n-n	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)
uniprotkb:P30419	uniprotkb:Q14790	intact:EBI-5280164|uniprotkb:A8K7C1|uniprotkb:Q9UE09|ensembl:ENSP00000258960|ensembl:ENSP00000468424|ensembl:ENSP00000504192	intact:EBI-78060|ensembl:ENSP00000412523|ensembl:ENSP00000501268|uniprotkb:Q14793|uniprotkb:Q14794|uniprotkb:Q14795|uniprotkb:Q14796|uniprotkb:Q15780|uniprotkb:Q15806|uniprotkb:Q53TT5|uniprotkb:Q8TDI1|uniprotkb:Q8TDI2|uniprotkb:Q8TDI3|uniprotkb:Q8TDI4|uniprotkb:Q8TDI5|uniprotkb:Q96T22|uniprotkb:Q9C0K4|uniprotkb:O14676|uniprotkb:Q14791|uniprotkb:Q14792|uniprotkb:Q9UQ81	psi-mi:nmt1_human(display_long)|uniprotkb:NMT1(gene name)|psi-mi:NMT1(display_short)|uniprotkb:NMT(gene name synonym)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 1"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 1(gene name synonym)	psi-mi:casp8_human(display_long)|uniprotkb:CASP8(gene name)|psi-mi:CASP8(display_short)|uniprotkb:MCH5(gene name synonym)|uniprotkb:ICE-like apoptotic protease 5(gene name synonym)|uniprotkb:MORT1-associated ced-3 homolog(gene name synonym)|uniprotkb:FADD-homologous ICE/ced-3-like protease(gene name synonym)|uniprotkb:FADD-like ICE(gene name synonym)|uniprotkb:Apoptotic cysteine protease(gene name synonym)|uniprotkb:Apoptotic protease Mch-5(gene name synonym)|uniprotkb:CAP4(gene name synonym)	psi-mi:"MI:0990"(cleavage assay)	Perinpanayagam et al. (2013)	pubmed:23150525|imex:IM-27162	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21278799|imex:IM-27162-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066565.1|ensembl:ENSG00000136448(gene)|ensembl:ENST00000258960(transcript)|ensembl:ENST00000592782(transcript)|ensembl:ENST00000676828(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019107"(myristoyltransferase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0042180"(cellular ketone metabolic process)|go:"GO:1900740"(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:1RXT|rcsb pdb:3IU1|rcsb pdb:3IU2|rcsb pdb:3IWE|rcsb pdb:3JTK|rcsb pdb:4C2Y|rcsb pdb:4C2Z|rcsb pdb:5MU6|rcsb pdb:5NPQ|rcsb pdb:5O6H|rcsb pdb:5O6J|rcsb pdb:5O9S|rcsb pdb:5O9T|rcsb pdb:5O9U|rcsb pdb:5O9V|rcsb pdb:5UUT|rcsb pdb:6EHJ|rcsb pdb:6F56|rcsb pdb:6FZ2|rcsb pdb:6FZ3|rcsb pdb:6FZ5|rcsb pdb:6PAV|rcsb pdb:6QRM|rcsb pdb:6SJZ|rcsb pdb:6SK2|rcsb pdb:6SK3|rcsb pdb:6SK8|rcsb pdb:6SKJ|reactome:R-HSA-162599|reactome:R-HSA-2514859|reactome:R-HSA-75108|go:"GO:0005737"(cytoplasm)	go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|ensembl:ENSG00000064012(gene)|ensembl:ENST00000432109(transcript)|ensembl:ENST00000673742(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0009409"(response to cold)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0070269"(pyroptosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097264"(self proteolysis)|go:"GO:0097342"(ripoptosome)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|reactome:R-HSA-264870|interpro:IPR001875(Death effector)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033170|mint:Q14790|rcsb pdb:1F9E|rcsb pdb:1I4E|rcsb pdb:1QDU|rcsb pdb:1QTN|rcsb pdb:2C2Z|rcsb pdb:2FUN|rcsb pdb:2K7Z|rcsb pdb:2Y1L|rcsb pdb:3H11|rcsb pdb:3KJN|rcsb pdb:3KJQ|rcsb pdb:4JJ7|rcsb pdb:4PRZ|rcsb pdb:4PS1|rcsb pdb:4ZBW|rcsb pdb:5H31|rcsb pdb:5H33|rcsb pdb:5JQE|rcsb pdb:5L08|rcsb pdb:6AGW|rcsb pdb:6PX9|reactome:R-HSA-111465|reactome:R-HSA-140534|reactome:R-HSA-168638|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5660668|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75108|reactome:R-HSA-75153|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9686347|reactome:R-HSA-9693928|refseq:NP_001073593.1|refseq:NP_001073594.1|refseq:NP_001219.2|refseq:NP_203519.1|refseq:NP_203520.1|refseq:NP_203522.1|refseq:XP_006712852.1|refseq:XP_006712853.1|refseq:XP_006712856.1|refseq:XP_005246944.1|refseq:XP_005246945.1|refseq:XP_005246946.1|refseq:XP_005246947.1|refseq:XP_005246948.1|refseq:XP_005246949.1|refseq:XP_005246943.1|dip:DIP-30915N	-	-	-	figure legend:Figure 4A-2|comment:The authors presume that  the nonspecific cleavage of His-NMT1 at D-38 by purified caspase-8 in vitro might be nonphysiological.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/03/20	rogid:eVkADRJp/cg4xIAw0ymeUZ+Vwyk9606	rogid:XKI9lMiIKZTtoY2lN/QIm1yTksY9606	rigid:D/JYzQXOlSRvomKaayHZzQDMPnQ	false	his tag:n-n|biological feature:38-39	his tag:n-n	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)
uniprotkb:O60551	uniprotkb:P42574	intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38	intact:EBI-524064|ensembl:ENSP00000311032|ensembl:ENSP00000428929|uniprotkb:Q96AN1|uniprotkb:Q96KP2|uniprotkb:A8K5M2|uniprotkb:D3DP53	psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym)	psi-mi:casp3_human(display_long)|uniprotkb:Apopain(gene name synonym)|uniprotkb:Cysteine protease CPP32(gene name synonym)|uniprotkb:Protein Yama(gene name synonym)|uniprotkb:SREBP cleavage activity 1(gene name synonym)|uniprotkb:CASP3(gene name)|psi-mi:CASP3(display_short)|uniprotkb:CPP32(gene name synonym)	psi-mi:"MI:0990"(cleavage assay)	Perinpanayagam et al. (2013)	pubmed:23150525|imex:IM-27162	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21278816|imex:IM-27162-5	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1	go:"GO:0009749"(response to glucose)|go:"GO:0001554"(luteolysis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002020"(protease binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000164305(gene)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|ensembl:ENST00000308394(transcript)|ensembl:ENST00000523916(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0008233"(peptidase activity)|go:"GO:0008627"(intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0016005"(phospholipase A2 activator activity)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016485"(protein processing)|go:"GO:0021766"(hippocampus development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035094"(response to nicotine)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061713"(anterior neural tube closure)|go:"GO:0071887"(leukocyte apoptotic process)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|rcsb pdb:1GFW|rcsb pdb:1I3O|rcsb pdb:1NME|rcsb pdb:1NMQ|rcsb pdb:1NMS|interpro:IPR015471(Caspase-7)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|mint:P42574|interpro:IPR002398(Peptidase C14, caspase precursor p45)|rcsb pdb:1CP3|rcsb pdb:4QUH|rcsb pdb:4QUI|rcsb pdb:4QUD|rcsb pdb:4QUJ|rcsb pdb:4QUL|rcsb pdb:5I9B|rcsb pdb:5I9T|rcsb pdb:5IAB|rcsb pdb:5IAE|rcsb pdb:5IAG|rcsb pdb:4QUE|rcsb pdb:5IAJ|rcsb pdb:4QUG|rcsb pdb:5IAK|rcsb pdb:5IAN|rcsb pdb:5IAR|rcsb pdb:5IAS|rcsb pdb:5IBC|rcsb pdb:5IBP|rcsb pdb:5IBR|rcsb pdb:5IC4|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111465|reactome:R-HSA-111469|reactome:R-HSA-140342|reactome:R-HSA-1474228|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-211736|reactome:R-HSA-264870|reactome:R-HSA-351906|reactome:R-HSA-418889|reactome:R-HSA-449836|reactome:R-HSA-5620971|reactome:R-HSA-111464|rcsb pdb:1QX3|rcsb pdb:1RE1|rcsb pdb:1RHJ|rcsb pdb:1RHK|rcsb pdb:1RHM|rcsb pdb:1RHQ|rcsb pdb:1RHR|rcsb pdb:1RHU|rcsb pdb:2C1E|rcsb pdb:2C2K|rcsb pdb:2C2M|rcsb pdb:2C2O|rcsb pdb:2CDR|rcsb pdb:2CJX|rcsb pdb:2CJY|rcsb pdb:2CNK|rcsb pdb:2CNL|rcsb pdb:2CNN|rcsb pdb:2CNO|rcsb pdb:2DKO|rcsb pdb:2H5I|rcsb pdb:2H5J|rcsb pdb:2H65|rcsb pdb:2J30|rcsb pdb:2J31|rcsb pdb:2J32|rcsb pdb:2J33|rcsb pdb:2XYG|rcsb pdb:2XYH|rcsb pdb:2XYP|rcsb pdb:2XZD|rcsb pdb:2XZT|rcsb pdb:2Y0B|rcsb pdb:3DEH|rcsb pdb:1PAU|rcsb pdb:3DEI|rcsb pdb:3DEJ|rcsb pdb:3DEK|rcsb pdb:3EDQ|rcsb pdb:3GJQ|rcsb pdb:3GJS|rcsb pdb:3GJT|rcsb pdb:3H0E|rcsb pdb:3ITN|rcsb pdb:3KJF|rcsb pdb:3PCX|rcsb pdb:3PD0|rcsb pdb:3PD1|rcsb pdb:4DCJ|rcsb pdb:4DCO|rcsb pdb:4DCP|rcsb pdb:4EHA|rcsb pdb:4EHD|rcsb pdb:4EHF|rcsb pdb:4EHH|rcsb pdb:4EHK|rcsb pdb:4EHL|rcsb pdb:4EHN|rcsb pdb:4JJE|rcsb pdb:4JQY|rcsb pdb:4JQZ|rcsb pdb:4JR0|rcsb pdb:4PRY|rcsb pdb:4PS0|rcsb pdb:4QTX|rcsb pdb:3GJR|rcsb pdb:4QTY|rcsb pdb:4QU0|rcsb pdb:4QU5|rcsb pdb:4QU8|rcsb pdb:4QU9|rcsb pdb:4QUA|rcsb pdb:4QUB|refseq:XP_011530603.1|refseq:NP_004337.2|refseq:NP_116786.1|dip:DIP-268N	-	-	-	figure legend:Figure 4A-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/15	2019/03/20	rogid:D0A45m14BXLRl69s94bURcQ2MhA9606	rogid:o7/WP52saFha1/FD2z1rIgVLDfI9606	rigid:BnKa55FJtjtLCkKFNnzeOgCFeqw	false	biological feature:67-68|his tag:n-n|biological feature:25-26	his tag:n-n	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)