#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P67775-1	uniprotkb:Q9Y570	intact:EBI-16765970|ensembl:ENSP00000418447	intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867	psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16765968|imex:IM-26337-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent)	refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273	intact:EBI-16766012(see-also)	-	-	figure legend:Figure 4C, 5G|comment:clone A4, C5.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/02/06	2018/02/19	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	rigid:6cfPUzYZb8x1hRoDu3itdPsRy1E	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P67775-1	uniprotkb:P30153	intact:EBI-16765970|ensembl:ENSP00000418447	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16765968|imex:IM-26337-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-16766012(see-also)	-	-	figure legend:Figure 4C, 5G|comment:clone A4, C5.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/02/06	2018/02/19	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rigid:6cfPUzYZb8x1hRoDu3itdPsRy1E	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P67775-1	uniprotkb:O75663	intact:EBI-16765970|ensembl:ENSP00000418447	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16765968|imex:IM-26337-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G	intact:EBI-16766012(see-also)	-	-	figure legend:Figure 4C, 5G|comment:clone A4, C5.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/02/06	2018/02/19	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rigid:6cfPUzYZb8x1hRoDu3itdPsRy1E	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P67775-1	uniprotkb:P78318	intact:EBI-16765970|ensembl:ENSP00000418447	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16765968|imex:IM-26337-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1	intact:EBI-16766012(see-also)	-	-	figure legend:Figure 4C, 5G|comment:clone A4, C5.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/02/06	2018/02/19	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	rigid:6cfPUzYZb8x1hRoDu3itdPsRy1E	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P67775-2	uniprotkb:O75663	intact:EBI-16766021	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:p67775-2(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha2(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16765984|imex:IM-26337-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-712311(isoform-parent)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G	-	isoform-comment:Catalytically inactive, shows enhanced binding to IGBP1, and does not interact with the scaffolding subunit PPP2R1A.	-	figure legend:Figure 4C-2,  5G.|comment:clone 3.4|comment:The interaction of PP2Aca2 with the PR65/A subunit was completely abolished, as was an interaction with PME1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/02/06	2018/02/15	rogid:rUGzQKvUy5KdnN0jz3FHpwxrRnU9606	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rigid:+SYvd1Y3kbTuvFdDnPJnnwEp3aI	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P67775-2	uniprotkb:P78318	intact:EBI-16766021	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	psi-mi:p67775-2(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha2(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16765984|imex:IM-26337-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-712311(isoform-parent)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1	-	isoform-comment:Catalytically inactive, shows enhanced binding to IGBP1, and does not interact with the scaffolding subunit PPP2R1A.	-	figure legend:Figure 4C-2,  5G.|comment:clone 3.4|comment:The interaction of PP2Aca2 with the PR65/A subunit was completely abolished, as was an interaction with PME1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/02/06	2018/02/15	rogid:rUGzQKvUy5KdnN0jz3FHpwxrRnU9606	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	rigid:+SYvd1Y3kbTuvFdDnPJnnwEp3aI	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O75663	uniprotkb:P67775-1	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	intact:EBI-16765970|ensembl:ENSP00000418447	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16766043|imex:IM-26337-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent)	-	-	-	figure legend:Figure 5A|comment:PME-1, TIPRL, and LCMT-1 all bind to both PP2Aca isoforms.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2018/02/06	2018/02/15	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rigid:t4QCYvPsdEXTDWRZbBrSSD4xusk	false	his tag:n-n|his tag:c-c	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75663	uniprotkb:P67775-2	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	intact:EBI-16766021	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:p67775-2(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha2(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16766053|imex:IM-26337-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G	intact:EBI-712311(isoform-parent)	-	-	isoform-comment:Catalytically inactive, shows enhanced binding to IGBP1, and does not interact with the scaffolding subunit PPP2R1A.	figure legend:Figure 5Ai|comment:PME-1, TIPRL, and LCMT-1 all bind to both PP2Aca isoforms.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2018/02/06	2018/02/15	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rogid:rUGzQKvUy5KdnN0jz3FHpwxrRnU9606	rigid:8zI+uh8qEH2EhpipZ78NWVICVUM	false	his tag:n-n|his tag:c-c	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y570	uniprotkb:P67775-2	intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867	intact:EBI-16766021	psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:p67775-2(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha2(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16766063|imex:IM-26337-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273	intact:EBI-712311(isoform-parent)	-	-	isoform-comment:Catalytically inactive, shows enhanced binding to IGBP1, and does not interact with the scaffolding subunit PPP2R1A.	figure legend:Figure 5B|comment:PME-1, TIPRL, and LCMT-1 all bind to both PP2Aca isoforms.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2018/02/06	2018/02/15	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	rogid:rUGzQKvUy5KdnN0jz3FHpwxrRnU9606	rigid:Yrw7phcHtB+90HSVw941UMn7DZs	false	his tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y570	uniprotkb:P67775-1	intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867	intact:EBI-16765970|ensembl:ENSP00000418447	psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16766074|imex:IM-26337-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent)	-	-	-	figure legend:Figure 5B-2|comment:PME-1, TIPRL, and LCMT-1 all bind to both PP2Aca isoforms.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2018/02/06	2018/02/15	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rigid:kpIpEhLBmO4Lj8y36yohum6Egks	false	his tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UIC8	uniprotkb:P67775-2	intact:EBI-747632|uniprotkb:A6NL89|uniprotkb:Q53FC5|uniprotkb:Q96CI5|uniprotkb:Q9NTG4|uniprotkb:Q9Y378|uniprotkb:Q9H6I9|uniprotkb:A8K770|ensembl:ENSP00000382021	intact:EBI-16766021	psi-mi:lcmt1_human(display_long)|uniprotkb:Protein-leucine O-methyltransferase(gene name synonym)|uniprotkb:LCMT1(gene name)|psi-mi:LCMT1(display_short)|uniprotkb:LCMT(gene name synonym)|uniprotkb:[Phosphatase 2A protein]-leucine-carboxy methyltransferase 1(gene name synonym)|uniprotkb:CGI-68(orf name)	psi-mi:p67775-2(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha2(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16766082|imex:IM-26337-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027563.1|refseq:NP_057393.2|refseq:XP_011544166.1|ensembl:ENSG00000205629(gene)|ensembl:ENST00000399069(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003880"(protein C-terminal carboxyl O-methyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006479"(protein methylation)|go:"GO:0006481"(C-terminal protein methylation)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0018423"(protein C-terminal leucine carboxyl O-methyltransferase activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|interpro:IPR007213(Leucine carboxyl methyltransferase)|interpro:IPR016651(Leucine carboxyl methyltransferase, LCTM1 1)|interpro:IPR029063|rcsb pdb:3IEI|rcsb pdb:3O7W|rcsb pdb:3P71|reactome:R-HSA-69273	intact:EBI-712311(isoform-parent)	-	-	isoform-comment:Catalytically inactive, shows enhanced binding to IGBP1, and does not interact with the scaffolding subunit PPP2R1A.	figure legend:Figure 5C|comment:PME-1, TIPRL, and LCMT-1 all bind to both PP2Aca  isoforms.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2018/02/06	2018/02/15	rogid:YNCPaQQoOXhlXr9kDqjt9XYjD9w9606	rogid:rUGzQKvUy5KdnN0jz3FHpwxrRnU9606	rigid:4Ehg5Bpr69o0eoFL/CUgFv/37nI	false	his tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UIC8	uniprotkb:P67775-1	intact:EBI-747632|uniprotkb:A6NL89|uniprotkb:Q53FC5|uniprotkb:Q96CI5|uniprotkb:Q9NTG4|uniprotkb:Q9Y378|uniprotkb:Q9H6I9|uniprotkb:A8K770|ensembl:ENSP00000382021	intact:EBI-16765970|ensembl:ENSP00000418447	psi-mi:lcmt1_human(display_long)|uniprotkb:Protein-leucine O-methyltransferase(gene name synonym)|uniprotkb:LCMT1(gene name)|psi-mi:LCMT1(display_short)|uniprotkb:LCMT(gene name synonym)|uniprotkb:[Phosphatase 2A protein]-leucine-carboxy methyltransferase 1(gene name synonym)|uniprotkb:CGI-68(orf name)	psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16766092|imex:IM-26337-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027563.1|refseq:NP_057393.2|refseq:XP_011544166.1|ensembl:ENSG00000205629(gene)|ensembl:ENST00000399069(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003880"(protein C-terminal carboxyl O-methyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006479"(protein methylation)|go:"GO:0006481"(C-terminal protein methylation)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0018423"(protein C-terminal leucine carboxyl O-methyltransferase activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|interpro:IPR007213(Leucine carboxyl methyltransferase)|interpro:IPR016651(Leucine carboxyl methyltransferase, LCTM1 1)|interpro:IPR029063|rcsb pdb:3IEI|rcsb pdb:3O7W|rcsb pdb:3P71|reactome:R-HSA-69273	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent)	-	-	-	figure legend:Figure 5C-2|comment:PME-1, TIPRL, and LCMT-1 all bind to both PP2Aca  isoforms.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2018/02/06	2018/02/15	rogid:YNCPaQQoOXhlXr9kDqjt9XYjD9w9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rigid:3Z563IiOq+IY+Nmye4FZzVL7KrA	false	his tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P67775-1	uniprotkb:P78318	intact:EBI-16765970|ensembl:ENSP00000418447	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16768057|imex:IM-26337-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1	-	-	-	figure legend:Figure 5F|comment:TIPRL was detected in association with the PP2Ac·a4 complex; however, neither PME-1 nor LCMT-1 were detected.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/02/06	2018/02/19	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	rigid:vfmRaQ8uTQgPCg6B3OMteBW/HBY	false	glutathione s tranferase tag:n-n	his tag:c-c|his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P67775-1	uniprotkb:O75663	intact:EBI-16765970|ensembl:ENSP00000418447	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16768057|imex:IM-26337-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G	-	-	-	figure legend:Figure 5F|comment:TIPRL was detected in association with the PP2Ac·a4 complex; however, neither PME-1 nor LCMT-1 were detected.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/02/06	2018/02/19	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rigid:vfmRaQ8uTQgPCg6B3OMteBW/HBY	false	glutathione s tranferase tag:n-n	his tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P67775-2	uniprotkb:P78318	intact:EBI-16766021	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	psi-mi:p67775-2(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha2(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16768074|imex:IM-26337-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-712311(isoform-parent)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1	-	isoform-comment:Catalytically inactive, shows enhanced binding to IGBP1, and does not interact with the scaffolding subunit PPP2R1A.	-	figure legend:Figure 5E|comment:TIPRL was detected in association with the PP2Ac·a4 complex; however, neither PME-1 nor LCMT-1 were detected.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/02/06	2018/02/19	rogid:rUGzQKvUy5KdnN0jz3FHpwxrRnU9606	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	rigid:+SYvd1Y3kbTuvFdDnPJnnwEp3aI	false	glutathione s tranferase tag:n-n	his tag:c-c|his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P67775-2	uniprotkb:O75663	intact:EBI-16766021	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:p67775-2(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha2(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Migueleti et al. (2012)	pubmed:22167190|imex:IM-26337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16768074|imex:IM-26337-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-712311(isoform-parent)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G	-	isoform-comment:Catalytically inactive, shows enhanced binding to IGBP1, and does not interact with the scaffolding subunit PPP2R1A.	-	figure legend:Figure 5E|comment:TIPRL was detected in association with the PP2Ac·a4 complex; however, neither PME-1 nor LCMT-1 were detected.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/02/06	2018/02/19	rogid:rUGzQKvUy5KdnN0jz3FHpwxrRnU9606	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rigid:+SYvd1Y3kbTuvFdDnPJnnwEp3aI	false	glutathione s tranferase tag:n-n	his tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)