#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q15038 uniprotkb:Q0VD86 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620612|imex:IM-26469-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/10 2018/07/10 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:FZcRZTmOROhyi8Xwy6HSf9EhFOY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BY78 uniprotkb:Q0VD86 intact:EBI-2129375|uniprotkb:Q542Y8|intact:EBI-2339452|intact:EBI-28972797|ensembl:ENSP00000312439 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:rnf26_human(display_long)|uniprotkb:RNF26(gene name)|psi-mi:RNF26(display_short)|uniprotkb:RING finger protein 26(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620631|imex:IM-26469-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000312439|refseq:NP_114404.1|ensembl:ENSG00000173456(gene)|ensembl:ENST00000311413(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040089 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/10 2018/07/10 rogid:R0awMKLLQSLU9zjVe/ivOWeYjnE9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:YFqTtJZQ6YmMU1p2m8fBKUJsjS0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P63244 uniprotkb:Q0VD86 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620635|imex:IM-26469-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/10 2018/07/10 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:IYE0BXZiBszCfZ47uY+Uz7NMny4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y4E8 uniprotkb:Q0VD86 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620639|imex:IM-26469-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/10 2018/07/10 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:iq2A+pDnWtFQH/awX8cYsvSu9F8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T280 uniprotkb:Q0VD86 intact:EBI-2880213|ensembl:ENSP00000354812|uniprotkb:Q6PIJ1|uniprotkb:Q6PJV9|uniprotkb:Q6P469|uniprotkb:Q6PGP9|uniprotkb:Q0D2P6 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:ci114_human(display_long)|uniprotkb:SPOUT1(gene name)|psi-mi:SPOUT1(display_short)|uniprotkb:C9orf114(gene name synonym)|uniprotkb:Centromere protein 32(gene name synonym)|uniprotkb:Kinetochore-associated protein(gene name synonym)|uniprotkb:SPOUT domain-containing methyltransferase 1(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620643|imex:IM-26469-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198917(gene)|ensembl:ENST00000361256(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032259"(methylation)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0072686"(mitotic spindle)|interpro:IPR003750(Protein of unknown function DUF171)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:4RG1|refseq:NP_057474.2 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/10 2018/07/10 rogid:xsCr/8Iqdx4wJ6XweqC73CSia749606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:ypPmjrXJ/Zxcxc+hbRiENbvd5Yo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12899 uniprotkb:Q0VD86 intact:EBI-2341136|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2|ensembl:ENSP00000331131|ensembl:ENSP00000373102|ensembl:ENSP00000379806|ensembl:ENSP00000389203|ensembl:ENSP00000390258|ensembl:ENSP00000391879|ensembl:ENSP00000392805|ensembl:ENSP00000393011|ensembl:ENSP00000394371|ensembl:ENSP00000394421|ensembl:ENSP00000395491|ensembl:ENSP00000396188|ensembl:ENSP00000398545|ensembl:ENSP00000402395|ensembl:ENSP00000406707|ensembl:ENSP00000407294|ensembl:ENSP00000407876|ensembl:ENSP00000408233|ensembl:ENSP00000409182|ensembl:ENSP00000410446|ensembl:ENSP00000414248|ensembl:ENSP00000415328|ensembl:ENSP00000415755|ensembl:ENSP00000416737 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620647|imex:IM-26469-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249434.1|refseq:XP_005249435.1|dip:DIP-52853N|ensembl:ENSG00000137313(gene)|ensembl:ENSG00000226060(gene)|ensembl:ENSG00000228881(gene)|ensembl:ENSG00000230230(gene)|ensembl:ENSG00000231002(gene)|ensembl:ENSG00000231641(gene)|ensembl:ENSG00000234046(gene)|ensembl:ENSG00000234127(gene)|ensembl:ENST00000327357(transcript)|ensembl:ENST00000383607(transcript)|ensembl:ENST00000396558(transcript)|ensembl:ENST00000415923(transcript)|ensembl:ENST00000422349(transcript)|ensembl:ENST00000425523(transcript)|ensembl:ENST00000425831(transcript)|ensembl:ENST00000427535(transcript)|ensembl:ENST00000428486(transcript)|ensembl:ENST00000432326(transcript)|ensembl:ENST00000433314(transcript)|ensembl:ENST00000436219(transcript)|ensembl:ENST00000437089(transcript)|ensembl:ENST00000438384(transcript)|ensembl:ENST00000438908(transcript)|ensembl:ENST00000439094(transcript)|ensembl:ENST00000445259(transcript)|ensembl:ENST00000447711(transcript)|ensembl:ENST00000450392(transcript)|ensembl:ENST00000453195(transcript)|ensembl:ENST00000454678(transcript)|ensembl:ENST00000455000(transcript)|ensembl:ENST00000456093(transcript)|ensembl:ENST00000456770(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|mint:Q12899|reactome:R-HSA-877300 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/10 2018/07/10 rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:cWV3xaSodX/wDUVKlxK4l43rgDs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51148 uniprotkb:Q0VD86 intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689|ensembl:ENSP00000377440 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620651|imex:IM-26469-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004574.2|refseq:NP_958842.1|refseq:XP_011523392.1|refseq:XP_011523393.1|refseq:NP_001238968.1|ensembl:ENSG00000108774(gene)|ensembl:ENST00000346213(transcript)|ensembl:ENST00000393860(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/10 2018/07/10 rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:8b/IP7fhOsjKwuvfwkipftAAei8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WYH8 uniprotkb:Q0VD86 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620655|imex:IM-26469-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/10 2018/07/10 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:CtIqnaxmIbOZtxhXnC3LLlJWfho false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BTV6 uniprotkb:Q0VD86 intact:EBI-11059920|uniprotkb:Q96AB7|ensembl:ENSP00000277540 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:dph7_human(display_long)|uniprotkb:DPH7(gene name)|psi-mi:DPH7(display_short)|uniprotkb:C9orf112(gene name synonym)|uniprotkb:Diphthamide biosynthesis protein 7(gene name synonym)|uniprotkb:WD repeat-containing protein 85(gene name synonym)|uniprotkb:WDR85(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620659|imex:IM-26469-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620133.1|ensembl:ENSG00000148399(gene)|ensembl:ENST00000277540(transcript)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0061685"(diphthine methylesterase activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|reactome:R-HSA-5358493 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2018/07/10 2018/07/10 rogid:B8+9JcX8gFSuQi66pETASoWLFgg9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:Pu7g2PmP08lN6pBwG++sv2kV/yU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15038 uniprotkb:Q0VD86 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0096"(pull down) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620623|imex:IM-26469-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1A|comment:"Nine known genes interacted with GST-INCA1(Fig. 1A, Table 1), but not with GST alone, indicating the specific interactions with INCA1 in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/10 2018/10/08 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:FZcRZTmOROhyi8Xwy6HSf9EhFOY false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9BTV6 uniprotkb:Q0VD86 intact:EBI-11059920|uniprotkb:Q96AB7|ensembl:ENSP00000277540 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:dph7_human(display_long)|uniprotkb:DPH7(gene name)|psi-mi:DPH7(display_short)|uniprotkb:C9orf112(gene name synonym)|uniprotkb:Diphthamide biosynthesis protein 7(gene name synonym)|uniprotkb:WD repeat-containing protein 85(gene name synonym)|uniprotkb:WDR85(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0096"(pull down) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620671|imex:IM-26469-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620133.1|ensembl:ENSG00000148399(gene)|ensembl:ENST00000277540(transcript)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0061685"(diphthine methylesterase activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|reactome:R-HSA-5358493 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1A|comment:"Nine known genes interacted with GST-INCA1(Fig. 1A, Table 1), but not with GST alone, indicating the specific interactions with INCA1 in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/10 2018/10/08 rogid:B8+9JcX8gFSuQi66pETASoWLFgg9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:Pu7g2PmP08lN6pBwG++sv2kV/yU false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8WYH8 uniprotkb:Q0VD86 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0096"(pull down) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620681|imex:IM-26469-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1A|comment:"Nine known genes interacted with GST-INCA1(Fig. 1A, Table 1), but not with GST alone, indicating the specific interactions with INCA1 in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/10 2018/10/08 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:CtIqnaxmIbOZtxhXnC3LLlJWfho false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9BY78 uniprotkb:Q0VD86 intact:EBI-2129375|uniprotkb:Q542Y8|intact:EBI-2339452|intact:EBI-28972797|ensembl:ENSP00000312439 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:rnf26_human(display_long)|uniprotkb:RNF26(gene name)|psi-mi:RNF26(display_short)|uniprotkb:RING finger protein 26(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0096"(pull down) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620691|imex:IM-26469-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000312439|refseq:NP_114404.1|ensembl:ENSG00000173456(gene)|ensembl:ENST00000311413(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040089 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1A|comment:"Nine known genes interacted with GST-INCA1(Fig. 1A, Table 1), but not with GST alone, indicating the specific interactions with INCA1 in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/10 2018/10/08 rogid:R0awMKLLQSLU9zjVe/ivOWeYjnE9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:YFqTtJZQ6YmMU1p2m8fBKUJsjS0 false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P63244 uniprotkb:Q0VD86 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0096"(pull down) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620701|imex:IM-26469-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1A|comment:"Nine known genes interacted with GST-INCA1(Fig. 1A, Table 1), but not with GST alone, indicating the specific interactions with INCA1 in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/10 2018/10/08 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:IYE0BXZiBszCfZ47uY+Uz7NMny4 false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9Y4E8 uniprotkb:Q0VD86 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0096"(pull down) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620711|imex:IM-26469-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1A|comment:"Nine known genes interacted with GST-INCA1(Fig. 1A, Table 1), but not with GST alone, indicating the specific interactions with INCA1 in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/10 2018/10/08 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:iq2A+pDnWtFQH/awX8cYsvSu9F8 false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q5T280 uniprotkb:Q0VD86 intact:EBI-2880213|ensembl:ENSP00000354812|uniprotkb:Q6PIJ1|uniprotkb:Q6PJV9|uniprotkb:Q6P469|uniprotkb:Q6PGP9|uniprotkb:Q0D2P6 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:ci114_human(display_long)|uniprotkb:SPOUT1(gene name)|psi-mi:SPOUT1(display_short)|uniprotkb:C9orf114(gene name synonym)|uniprotkb:Centromere protein 32(gene name synonym)|uniprotkb:Kinetochore-associated protein(gene name synonym)|uniprotkb:SPOUT domain-containing methyltransferase 1(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0096"(pull down) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620731|imex:IM-26469-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198917(gene)|ensembl:ENST00000361256(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032259"(methylation)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0072686"(mitotic spindle)|interpro:IPR003750(Protein of unknown function DUF171)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:4RG1|refseq:NP_057474.2 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1A|comment:"Nine known genes interacted with GST-INCA1(Fig. 1A, Table 1), but not with GST alone, indicating the specific interactions with INCA1 in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/10 2018/10/08 rogid:xsCr/8Iqdx4wJ6XweqC73CSia749606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:ypPmjrXJ/Zxcxc+hbRiENbvd5Yo false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q12899 uniprotkb:Q0VD86 intact:EBI-2341136|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2|ensembl:ENSP00000331131|ensembl:ENSP00000373102|ensembl:ENSP00000379806|ensembl:ENSP00000389203|ensembl:ENSP00000390258|ensembl:ENSP00000391879|ensembl:ENSP00000392805|ensembl:ENSP00000393011|ensembl:ENSP00000394371|ensembl:ENSP00000394421|ensembl:ENSP00000395491|ensembl:ENSP00000396188|ensembl:ENSP00000398545|ensembl:ENSP00000402395|ensembl:ENSP00000406707|ensembl:ENSP00000407294|ensembl:ENSP00000407876|ensembl:ENSP00000408233|ensembl:ENSP00000409182|ensembl:ENSP00000410446|ensembl:ENSP00000414248|ensembl:ENSP00000415328|ensembl:ENSP00000415755|ensembl:ENSP00000416737 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0096"(pull down) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620741|imex:IM-26469-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249434.1|refseq:XP_005249435.1|dip:DIP-52853N|ensembl:ENSG00000137313(gene)|ensembl:ENSG00000226060(gene)|ensembl:ENSG00000228881(gene)|ensembl:ENSG00000230230(gene)|ensembl:ENSG00000231002(gene)|ensembl:ENSG00000231641(gene)|ensembl:ENSG00000234046(gene)|ensembl:ENSG00000234127(gene)|ensembl:ENST00000327357(transcript)|ensembl:ENST00000383607(transcript)|ensembl:ENST00000396558(transcript)|ensembl:ENST00000415923(transcript)|ensembl:ENST00000422349(transcript)|ensembl:ENST00000425523(transcript)|ensembl:ENST00000425831(transcript)|ensembl:ENST00000427535(transcript)|ensembl:ENST00000428486(transcript)|ensembl:ENST00000432326(transcript)|ensembl:ENST00000433314(transcript)|ensembl:ENST00000436219(transcript)|ensembl:ENST00000437089(transcript)|ensembl:ENST00000438384(transcript)|ensembl:ENST00000438908(transcript)|ensembl:ENST00000439094(transcript)|ensembl:ENST00000445259(transcript)|ensembl:ENST00000447711(transcript)|ensembl:ENST00000450392(transcript)|ensembl:ENST00000453195(transcript)|ensembl:ENST00000454678(transcript)|ensembl:ENST00000455000(transcript)|ensembl:ENST00000456093(transcript)|ensembl:ENST00000456770(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|mint:Q12899|reactome:R-HSA-877300 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1A|comment:"Nine known genes interacted with GST-INCA1(Fig. 1A, Table 1), but not with GST alone, indicating the specific interactions with INCA1 in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/10 2018/10/08 rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:cWV3xaSodX/wDUVKlxK4l43rgDs false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P51148 uniprotkb:Q0VD86 intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689|ensembl:ENSP00000377440 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0096"(pull down) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20620751|imex:IM-26469-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004574.2|refseq:NP_958842.1|refseq:XP_011523392.1|refseq:XP_011523393.1|refseq:NP_001238968.1|ensembl:ENSG00000108774(gene)|ensembl:ENST00000346213(transcript)|ensembl:ENST00000393860(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1A|comment:"Nine known genes interacted with GST-INCA1(Fig. 1A, Table 1), but not with GST alone, indicating the specific interactions with INCA1 in vitro."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/10 2018/10/08 rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:8b/IP7fhOsjKwuvfwkipftAAei8 false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8WYH8 uniprotkb:Q0VD86 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20621013|imex:IM-26469-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1B|caution:Curator referred to what was reported in the figure and not to what was reported in Figure Legend.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2018/07/10 2018/07/11 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:CtIqnaxmIbOZtxhXnC3LLlJWfho false - green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8WYH8 uniprotkb:Q0VD86 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2010) imex:IM-26469|pubmed:21750715 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20621019|imex:IM-26469-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1 - - - figure legend:Fig. 1C|caution:Curator referred to what was reported in the figure and not to what was reported in Figure Legend.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2018/07/10 2018/07/11 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rigid:CtIqnaxmIbOZtxhXnC3LLlJWfho false - green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)