#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P63142 uniprotkb:P62483 intact:EBI-631446|uniprotkb:P15386|uniprotkb:Q02010|ensembl:ENSRNOP00000042653|ensembl:ENSRNOP00000075841|ensembl:ENSRNOP00000075852 intact:EBI-771110|uniprotkb:Q60942|uniprotkb:Q64284|uniprotkb:P97381|ensembl:ENSRNOP00000015840 psi-mi:kcna2_rat(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv1.2(gene name synonym)|uniprotkb:RBK2(gene name synonym)|uniprotkb:RCK5(gene name synonym)|uniprotkb:RAK(gene name synonym)|uniprotkb:Kcna2(gene name)|psi-mi:Kcna2(display_short) psi-mi:kcab2_rat(display_long)|uniprotkb:"K(+) channel subunit beta-2"(gene name synonym)|uniprotkb:Kv-beta-2(gene name synonym)|uniprotkb:Kcnab2(gene name)|psi-mi:Kcnab2(display_short)|uniprotkb:Ckbeta2(gene name synonym)|uniprotkb:Kcnb3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Vacher et al. (2011) pubmed:21357749|imex:IM-26847 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20827206|imex:IM-26847-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2950|refseq:NP_037102.1|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:1DSX|rcsb pdb:1QDV|rcsb pdb:1QDW|rcsb pdb:2A79|rcsb pdb:2R9R|rcsb pdb:3LNM|rcsb pdb:3LUT|rcsb pdb:4JTA|rcsb pdb:4JTC|rcsb pdb:4JTD|rcsb pdb:5WIE|rcsb pdb:6EBK|rcsb pdb:6EBL|rcsb pdb:6EBM|interpro:IPR005821(Ion transport)|reactome:R-RNO-1296072|ensembl:ENSRNOG00000018285(gene)|ensembl:ENSRNOT00000050149(transcript)|ensembl:ENSRNOT00000092365(transcript)|ensembl:ENSRNOT00000092450(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019894"(kinesin binding)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004049(Potassium channel, voltage dependent, Kv1.2)|go:"GO:0014059"(regulation of dopamine secretion)|refseq:XP_008759593.1|refseq:XP_006233194.1|refseq:XP_006233195.1|refseq:XP_006233196.1|refseq:XP_006233197.1 rgd:61828|refseq:NP_059000.1|ensembl:ENSRNOG00000011550(gene)|ensembl:ENSRNOT00000015840(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034705"(potassium channel complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0050905"(neuromuscular process)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0098900"(regulation of action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1990031"(pinceau fiber)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR005399(Potassium channel, voltage-dependent, beta subunit, KCNAB-related)|interpro:IPR005401(Potassium channel, voltage-dependent, beta subunit, KCNAB2)|interpro:IPR005983(Potassium channel, voltage-dependent, beta subunit, KCNAB)|interpro:IPR023210|interpro:IPR036812|rcsb pdb:1EXB|rcsb pdb:1QRQ|rcsb pdb:2A79|rcsb pdb:2R9R|rcsb pdb:3EAU|rcsb pdb:3EB3|rcsb pdb:3EB4|rcsb pdb:3LNM|rcsb pdb:3LUT|rcsb pdb:4JTA|rcsb pdb:4JTC|rcsb pdb:4JTD|rcsb pdb:5WIE|rcsb pdb:6CI1|rcsb pdb:6EBK|rcsb pdb:6EBL|reactome:R-RNO-1296072|reactome:R-RNO-6798695 - - - figure legend:Table 1. Fig.1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2018/11/09 2018/11/09 rogid:AimFojHr+yjzzdtmfxUCRBTvJyc10116 rogid:ZWu/Ez0ginUniSAUbIGXgod3iqg10116 rigid:r1h7VMQiLaDIJ10gdple+lj9b/s false - O-phospho-L-serine:9-9|O-phospho-L-serine:20-20|O-phospho-L-serine:31-31|O-phospho-L-serine:112-112 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63141 uniprotkb:P62482 intact:EBI-644033|uniprotkb:P15386|uniprotkb:Q02010|uniprotkb:Q8C8W4|uniprotkb:B2RS05|ensembl:ENSMUSP00000041702|ensembl:ENSMUSP00000142873|ensembl:ENSMUSP00000143798 intact:EBI-771096|uniprotkb:P97381|uniprotkb:Q60942|uniprotkb:Q64284|ensembl:ENSMUSP00000101273|ensembl:ENSMUSP00000125058 psi-mi:kcna2_mouse(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv1.2(gene name synonym)|uniprotkb:Kcna2(gene name)|psi-mi:Kcna2(display_short)|uniprotkb:MK2(gene name synonym) psi-mi:kcab2_mouse(display_long)|uniprotkb:"K(+) channel subunit beta-2"(gene name synonym)|uniprotkb:Kv-beta-2(gene name synonym)|uniprotkb:Neuroimmune protein F5(gene name synonym)|uniprotkb:Kcnab2(gene name)|psi-mi:Kcnab2(display_short)|uniprotkb:Ckbeta2(gene name synonym)|uniprotkb:I2rf5(gene name synonym)|uniprotkb:Kcnb3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Vacher et al. (2011) pubmed:21357749|imex:IM-26847 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20827231|imex:IM-26847-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032443.3|ensembl:ENSMUSG00000040724(gene)|ensembl:ENSMUST00000038695(transcript)|ensembl:ENSMUST00000196403(transcript)|ensembl:ENSMUST00000197470(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019894"(kinesin binding)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004049(Potassium channel, voltage dependent, Kv1.2)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:5WIE|reactome:R-MMU-1296072|refseq:XP_006501113.1|refseq:XP_006501114.1|refseq:XP_006501111.1|refseq:XP_006501112.1|refseq:XP_006501115.1|refseq:XP_006501116.1|refseq:XP_006501117.1|refseq:XP_006501118.1|dip:DIP-32239N refseq:NP_034728.2|refseq:XP_017175485.1|refseq:NP_001239585.1|ensembl:ENSMUSG00000028931(gene)|ensembl:ENSMUST00000105648(transcript)|ensembl:ENSMUST00000160884(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034705"(potassium channel complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0050905"(neuromuscular process)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0098900"(regulation of action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1990031"(pinceau fiber)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR005399(Potassium channel, voltage-dependent, beta subunit, KCNAB-related)|interpro:IPR005401(Potassium channel, voltage-dependent, beta subunit, KCNAB2)|interpro:IPR005983(Potassium channel, voltage-dependent, beta subunit, KCNAB)|interpro:IPR023210|interpro:IPR036812|mint:P62482|reactome:R-MMU-1296072|reactome:R-MMU-6798695 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2018/11/09 2018/11/09 rogid:AimFojHr+yjzzdtmfxUCRBTvJyc10090 rogid:ZWu/Ez0ginUniSAUbIGXgod3iqg10090 rigid:7rD3wCrMz4JXb8+VxdMamPUJZHo false - O-phospho-L-serine:20-20|O-phospho-L-serine:112-112 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16389 uniprotkb:Q13303 intact:EBI-10210559|uniprotkb:A0A024R0D3|uniprotkb:A8K1Z6|uniprotkb:Q86XG6|ensembl:ENSP00000314520|ensembl:ENSP00000487785|ensembl:ENSP00000491613|ensembl:ENSP00000491977|ensembl:ENSP00000502642|ensembl:ENSP00000433109 intact:EBI-948729|ensembl:ENSP00000164247|ensembl:ENSP00000367332|ensembl:ENSP00000367337|ensembl:ENSP00000400285|ensembl:ENSP00000499496|uniprotkb:Q6ZNE4|uniprotkb:A0AVM9|uniprotkb:O43659|uniprotkb:Q5TG82|uniprotkb:Q5TG83|uniprotkb:Q99411|uniprotkb:A8K1A4|uniprotkb:B0AZR7|uniprotkb:Q2YD85 psi-mi:kcna2_human(display_long)|uniprotkb:KCNA2(gene name)|psi-mi:KCNA2(display_short)|uniprotkb:NGK1(gene name synonym)|uniprotkb:"Voltage-gated K(+) channel HuKIV"(gene name synonym)|uniprotkb:Voltage-gated potassium channel HBK5(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv1.2(gene name synonym) psi-mi:kcab2_human(display_long)|uniprotkb:"K(+) channel subunit beta-2"(gene name synonym)|uniprotkb:Kv-beta-2(gene name synonym)|uniprotkb:KCNAB2(gene name)|psi-mi:KCNAB2(display_short)|uniprotkb:KCNA2B(gene name synonym)|uniprotkb:KCNK2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Vacher et al. (2011) pubmed:21357749|imex:IM-26847 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20827245|imex:IM-26847-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016856702.1|refseq:NP_001191198.1|refseq:NP_004965.1|refseq:XP_011539698.1|refseq:XP_011539699.1|refseq:XP_011539700.1|refseq:XP_011539701.1|refseq:XP_011539702.1|ensembl:ENSG00000177301(gene)|ensembl:ENST00000316361(transcript)|ensembl:ENST00000485317(transcript)|ensembl:ENST00000633222(transcript)|ensembl:ENST00000638532(transcript)|ensembl:ENST00000638616(transcript)|ensembl:ENST00000675391(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019894"(kinesin binding)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004049(Potassium channel, voltage dependent, Kv1.2)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|reactome:R-HSA-1296072 ensembl:ENSG00000069424(gene)|ensembl:ENST00000164247(transcript)|ensembl:ENST00000378092(transcript)|ensembl:ENST00000378097(transcript)|ensembl:ENST00000428161(transcript)|ensembl:ENST00000671676(transcript)|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0098900"(regulation of action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1990031"(pinceau fiber)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR005399(Potassium channel, voltage-dependent, beta subunit, KCNAB-related)|interpro:IPR005401(Potassium channel, voltage-dependent, beta subunit, KCNAB2)|interpro:IPR005983(Potassium channel, voltage-dependent, beta subunit, KCNAB)|interpro:IPR023210|interpro:IPR036812|rcsb pdb:1ZSX|rcsb pdb:7EJ1|rcsb pdb:7EJ2|reactome:R-HSA-1296072|reactome:R-HSA-6798695|refseq:NP_001186789.1|refseq:NP_001186790.1|refseq:NP_001186791.1|refseq:NP_003627.1|refseq:NP_742128.1|refseq:XP_011540623.1|refseq:XP_011540624.1|refseq:XP_005263571.1|refseq:NP_001186792.1 - - - figure legend:Table 1. Fig.1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-brain-hippocampus)|taxid:9606(Homo sapiens hippocampus) - 2018/11/09 2018/11/09 rogid:X6Ya/QiaX/5xnYuwP2gLBAuwUhM9606 rogid:xH22lEz6vYy0yIz7gNUS91SkeMs9606 rigid:kEXopYxt1brupwOSXgdC5reTnDo false - O-phospho-L-serine:31-31|O-phospho-L-serine:112-112 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)